Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

SNED1 TRPM4 OIT3 NOTCH2NLB MBL2 NID1 ADAMTS13 LRP1B FBN3 NOTCH1 NOTCH2 NOTCH3

3.89e-067496412GO:0005509
GeneOntologyMolecularFunctionstructural constituent of skin epidermis

KRT81 KRT83 KRT86 KRT73

1.08e-0543644GO:0030280
GeneOntologyMolecularFunctionNotch binding

SNED1 NOTCH2NLB NOTCH1

8.69e-0527643GO:0005112
GeneOntologyMolecularFunctionstructural molecule activity

MUC17 KRTAP3-3 KRT81 KRT83 KRT86 LAMA2 NID1 SSPOP KRTAP27-1 FBN3 KRT73

1.12e-048916411GO:0005198
GeneOntologyMolecularFunctionextracellular matrix structural constituent

MUC17 LAMA2 NID1 SSPOP FBN3

3.41e-04188645GO:0005201
GeneOntologyBiologicalProcesscellular response to tumor cell

NOTCH1 NOTCH2

2.93e-053652GO:0071228
GeneOntologyBiologicalProcessintermediate filament organization

KRT81 KRT83 KRT86 KRT73

9.23e-0575654GO:0045109
GeneOntologyBiologicalProcessfollicular B cell differentiation

IRF8 MUC19

9.72e-055652GO:0002316
GeneOntologyBiologicalProcessglomerulus development

NID1 NOTCH1 NOTCH2 NOTCH3

1.02e-0477654GO:0032835
GeneOntologyBiologicalProcessglomerulus vasculature development

NOTCH1 NOTCH2 NOTCH3

1.14e-0430653GO:0072012
GeneOntologyBiologicalProcesskidney vasculature development

NOTCH1 NOTCH2 NOTCH3

1.26e-0431653GO:0061440
GeneOntologyBiologicalProcessrenal system vasculature development

NOTCH1 NOTCH2 NOTCH3

1.26e-0431653GO:0061437
GeneOntologyBiologicalProcessglomerulus vasculature morphogenesis

NOTCH2 NOTCH3

1.45e-046652GO:0072103
GeneOntologyBiologicalProcessglomerular capillary formation

NOTCH2 NOTCH3

1.45e-046652GO:0072104
GeneOntologyBiologicalProcesskeratinization

KRT81 KRT83 KRT86 KRT73

1.64e-0487654GO:0031424
GeneOntologyBiologicalProcessrenal system vasculature morphogenesis

NOTCH2 NOTCH3

2.03e-047652GO:0061438
GeneOntologyBiologicalProcesskidney vasculature morphogenesis

NOTCH2 NOTCH3

2.03e-047652GO:0061439
GeneOntologyBiologicalProcessmature B cell differentiation involved in immune response

IRF8 MUC19 NOTCH2

2.33e-0438653GO:0002313
GeneOntologyBiologicalProcessintermediate filament cytoskeleton organization

KRT81 KRT83 KRT86 KRT73

2.70e-0499654GO:0045104
GeneOntologyBiologicalProcessepidermal cell differentiation

KRT81 KRT83 KRT86 USH2A NOTCH1 KRT73

2.70e-04284656GO:0009913
GeneOntologyBiologicalProcessintermediate filament-based process

KRT81 KRT83 KRT86 KRT73

2.81e-04100654GO:0045103
GeneOntologyBiologicalProcesskeratinocyte differentiation

KRT81 KRT83 KRT86 NOTCH1 KRT73

3.24e-04189655GO:0030216
GeneOntologyBiologicalProcessatrioventricular node development

NOTCH1 NOTCH2

3.47e-049652GO:0003162
GeneOntologyBiologicalProcesspositive regulation of muscle cell differentiation

LAMA2 NID1 NOTCH1 NOTCH2

3.51e-04106654GO:0051149
GeneOntologyBiologicalProcessmature B cell differentiation

IRF8 MUC19 NOTCH2

4.39e-0447653GO:0002335
GeneOntologyBiologicalProcessNotch signaling pathway

NOTCH2NLB PRAG1 NOTCH1 NOTCH2 NOTCH3

5.25e-04210655GO:0007219
GeneOntologyBiologicalProcessglomerulus morphogenesis

NOTCH2 NOTCH3

5.28e-0411652GO:0072102
GeneOntologyBiologicalProcessnegative regulation of calcium ion-dependent exocytosis

CBARP NOTCH1

5.28e-0411652GO:0045955
GeneOntologyBiologicalProcessregulation of basement membrane organization

LAMA2 NID1

5.28e-0411652GO:0110011
GeneOntologyBiologicalProcessRas protein signal transduction

RIT1 RALGPS1 NOTCH1 NOTCH2

7.15e-04128654GO:0007265
GeneOntologyBiologicalProcesspositive regulation of integrin-mediated signaling pathway

LAMA2 NID1

8.68e-0414652GO:2001046
GeneOntologyBiologicalProcessleft/right axis specification

NOTCH1 NOTCH2

8.68e-0414652GO:0070986
GeneOntologyCellularComponentkeratin filament

KRTAP3-3 KRT81 KRT83 KRT86 KRTAP27-1 KRT73

5.15e-0797646GO:0045095
GeneOntologyCellularComponentintermediate filament

KRTAP3-3 KRT81 KRT83 KRT86 KRTAP27-1 KRT73

6.80e-05227646GO:0005882
GeneOntologyCellularComponentintermediate filament cytoskeleton

KRTAP3-3 KRT81 KRT83 KRT86 KRTAP27-1 KRT73

1.52e-04263646GO:0045111
GeneOntologyCellularComponentextracellular matrix

SNED1 FCGBP MUC17 LAMA2 NID1 ADAMTS13 USH2A SSPOP FBN3

1.65e-04656649GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

SNED1 FCGBP MUC17 LAMA2 NID1 ADAMTS13 USH2A SSPOP FBN3

1.69e-04658649GO:0030312
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

LAMA2 NID1

1.22e-0317642GO:0098637
HumanPhenoPerifollicular hyperkeratosis

KRT81 KRT83 KRT86

1.48e-074183HP:0007468
HumanPhenoAbnormal perifollicular morphology

KRT81 KRT83 KRT86

7.36e-076183HP:0031285
HumanPhenoAbnormality of hair texture

RIT1 KRT81 KRT83 KRT86 GNS NOTCH2 NOTCH3

3.33e-05290187HP:0010719
HumanPhenoCoarse hair

RIT1 GNS NOTCH2 NOTCH3

4.11e-0558184HP:0002208
HumanPhenoLocalized skin lesion

RIT1 TRPM4 KRT81 KRT83 KRT86 AIRE PHOX2B NOTCH1 NOTCH2 NOTCH3 CAPN15

4.54e-058971811HP:0011355
HumanPhenoPatchy alopecia

KRT81 KRT83 KRT86

9.16e-0526183HP:0002232
HumanPhenoSchizophrenia

KRT81 KRT83 KRT86 USH2A

1.20e-0476184HP:0100753
HumanPhenoAbnormality of hair growth rate

KRT81 KRT83 KRT86

1.28e-0429183HP:0011363
HumanPhenoSlow-growing hair

KRT81 KRT83 KRT86

1.28e-0429183HP:0002217
HumanPhenoFollicular hyperkeratosis

KRT81 KRT83 KRT86

1.42e-0430183HP:0007502
HumanPhenoAbnormality of hair growth

KRT81 KRT83 KRT86

1.42e-0430183HP:0040170
HumanPhenoNail dystrophy

KRT81 KRT83 KRT86 AIRE NOTCH1

1.57e-04156185HP:0008404
HumanPhenoAbnormal hair pattern

RIT1 KRT81 KRT83 KRT86 ZNF407 GNS NOTCH2 NOTCH3 CAPN15

1.92e-04676189HP:0010720
HumanPhenoNail dysplasia

KRT81 KRT83 KRT86 AIRE NOTCH1 NOTCH2

2.00e-04264186HP:0002164
HumanPhenoKeratosis pilaris

KRT81 KRT83 KRT86

2.67e-0437183HP:0032152
HumanPhenoAbnormal hair quantity

RIT1 KRT81 KRT83 KRT86 AIRE ZNF407 GNS NOTCH1 NOTCH2 CAPN15

2.79e-048881810HP:0011362
HumanPhenoAcquired abnormal hair pattern

KRT81 KRT83 KRT86

4.48e-0444183HP:0011360
DomainEGF_1

SNED1 HGFAC OIT3 MUC17 LAMA2 NID1 USH2A LRP1B SSPOP FBN3 NOTCH1 NOTCH2 NOTCH3

1.93e-122556213PS00022
DomainEGF

SNED1 HGFAC FCGBP OIT3 MUC17 LAMA2 NID1 LRP1B FBN3 NOTCH1 NOTCH2 NOTCH3

1.47e-112356212SM00181
DomainEGF-like_dom

SNED1 HGFAC FCGBP OIT3 MUC17 LAMA2 NID1 LRP1B FBN3 NOTCH1 NOTCH2 NOTCH3

2.90e-112496212IPR000742
DomainEGF_2

SNED1 HGFAC OIT3 MUC17 LAMA2 NID1 LRP1B SSPOP FBN3 NOTCH1 NOTCH2 NOTCH3

5.97e-112656212PS01186
DomainEGF_3

SNED1 HGFAC OIT3 MUC17 NID1 LRP1B SSPOP FBN3 NOTCH1 NOTCH2 NOTCH3

2.86e-102356211PS50026
DomainEGF_Ca-bd_CS

SNED1 OIT3 NID1 LRP1B FBN3 NOTCH1 NOTCH2 NOTCH3

1.06e-0997628IPR018097
DomainEGF_CA

SNED1 OIT3 NID1 LRP1B FBN3 NOTCH1 NOTCH2 NOTCH3

1.25e-0999628PS01187
DomainASX_HYDROXYL

SNED1 OIT3 NID1 LRP1B FBN3 NOTCH1 NOTCH2 NOTCH3

1.35e-09100628PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

SNED1 OIT3 NID1 LRP1B FBN3 NOTCH1 NOTCH2 NOTCH3

2.16e-09106628IPR000152
DomainEGF_CA

SNED1 OIT3 NID1 LRP1B FBN3 NOTCH1 NOTCH2 NOTCH3

6.62e-09122628SM00179
DomainEGF-like_Ca-bd_dom

SNED1 OIT3 NID1 LRP1B FBN3 NOTCH1 NOTCH2 NOTCH3

7.53e-09124628IPR001881
DomainEGF

SNED1 HGFAC NID1 LRP1B FBN3 NOTCH1 NOTCH2 NOTCH3

8.54e-09126628PF00008
DomainEGF-like_CS

SNED1 HGFAC MUC17 LAMA2 NID1 LRP1B FBN3 NOTCH1 NOTCH2 NOTCH3

1.36e-082616210IPR013032
DomainhEGF

SNED1 FBN3 NOTCH1 NOTCH2 NOTCH3

3.17e-0828625PF12661
DomainDUF3454

NOTCH1 NOTCH2 NOTCH3

3.48e-083623PF11936
DomainDUF3454_notch

NOTCH1 NOTCH2 NOTCH3

3.48e-083623IPR024600
DomainDUF3454

NOTCH1 NOTCH2 NOTCH3

3.48e-083623SM01334
DomainGrowth_fac_rcpt_

KRT83 NID1 HTRA4 LRP1B FBN3 NOTCH1 NOTCH2 NOTCH3

4.56e-08156628IPR009030
DomainNotch

NOTCH1 NOTCH2 NOTCH3

1.39e-074623IPR008297
DomainNODP

NOTCH1 NOTCH2 NOTCH3

1.39e-074623PF07684
DomainNotch_NODP_dom

NOTCH1 NOTCH2 NOTCH3

1.39e-074623IPR011656
DomainNotch_NOD_dom

NOTCH1 NOTCH2 NOTCH3

1.39e-074623IPR010660
DomainNOD

NOTCH1 NOTCH2 NOTCH3

1.39e-074623PF06816
DomainNOD

NOTCH1 NOTCH2 NOTCH3

1.39e-074623SM01338
DomainNODP

NOTCH1 NOTCH2 NOTCH3

1.39e-074623SM01339
DomainLNR

NOTCH1 NOTCH2 NOTCH3

3.47e-075623PS50258
DomainEGF_CA

NID1 LRP1B FBN3 NOTCH1 NOTCH2 NOTCH3

3.99e-0786626PF07645
DomainKeratin_2_head

KRT81 KRT83 KRT86 KRT73

1.11e-0624624IPR032444
DomainKeratin_2_head

KRT81 KRT83 KRT86 KRT73

1.11e-0624624PF16208
DomainNotch_dom

NOTCH1 NOTCH2 NOTCH3

1.21e-067623IPR000800
DomainNotch

NOTCH1 NOTCH2 NOTCH3

1.21e-067623PF00066
DomainNL

NOTCH1 NOTCH2 NOTCH3

1.21e-067623SM00004
DomainKeratin_II

KRT81 KRT83 KRT86 KRT73

1.56e-0626624IPR003054
DomainTIL

FCGBP MUC19 SSPOP

7.50e-0612623PF01826
DomainC8

FCGBP MUC19 SSPOP

7.50e-0612623PF08742
DomainLDLR_class-A_CS

LRP3 TMPRSS7 LRP1B SSPOP

9.20e-0640624IPR023415
DomainUnchr_dom_Cys-rich

FCGBP MUC19 SSPOP

9.73e-0613623IPR014853
DomainC8

FCGBP MUC19 SSPOP

9.73e-0613623SM00832
DomainTIL_dom

FCGBP MUC19 SSPOP

1.24e-0514623IPR002919
DomainLdl_recept_a

LRP3 TMPRSS7 LRP1B SSPOP

1.48e-0545624PF00057
Domain-

LRP3 TMPRSS7 LRP1B SSPOP

1.62e-05466244.10.400.10
DomainVWD

FCGBP MUC19 SSPOP

1.89e-0516623SM00216
DomainVWF_type-D

FCGBP MUC19 SSPOP

1.89e-0516623IPR001846
DomainVWFD

FCGBP MUC19 SSPOP

1.89e-0516623PS51233
DomainVWD

FCGBP MUC19 SSPOP

1.89e-0516623PF00094
DomainLDLRA_1

LRP3 TMPRSS7 LRP1B SSPOP

1.92e-0548624PS01209
DomainLDLRA_2

LRP3 TMPRSS7 LRP1B SSPOP

2.09e-0549624PS50068
DomainLDrepeatLR_classA_rpt

LRP3 TMPRSS7 LRP1B SSPOP

2.09e-0549624IPR002172
DomainLDLa

LRP3 TMPRSS7 LRP1B SSPOP

2.09e-0549624SM00192
DomainVWC_out

FCGBP MUC19 SSPOP

3.25e-0519623SM00215
DomainIntermediate_filament_CS

KRT81 KRT83 KRT86 KRT73

5.66e-0563624IPR018039
DomaincEGF

NID1 LRP1B FBN3

8.58e-0526623IPR026823
DomaincEGF

NID1 LRP1B FBN3

8.58e-0526623PF12662
DomainFilament

KRT81 KRT83 KRT86 KRT73

9.06e-0571624SM01391
DomainIF

KRT81 KRT83 KRT86 KRT73

9.56e-0572624PS00226
DomainFilament

KRT81 KRT83 KRT86 KRT73

1.01e-0473624PF00038
DomainNIDO_dom

SNED1 NID1

1.08e-045622IPR003886
DomainNIDO

SNED1 NID1

1.08e-045622SM00539
DomainNIDO

SNED1 NID1

1.08e-045622PF06119
DomainNIDO

SNED1 NID1

1.08e-045622PS51220
DomainIF

KRT81 KRT83 KRT86 KRT73

1.18e-0476624IPR001664
DomainVWC

FCGBP MUC19 SSPOP

2.71e-0438623SM00214
Domain-

TRIM56 NID1 LRP1B

2.92e-04396232.120.10.30
DomainVWF_dom

FCGBP MUC19 SSPOP

3.65e-0442623IPR001007
Domain6-blade_b-propeller_TolB-like

TRIM56 NID1 LRP1B

4.78e-0446623IPR011042
DomainFol_N

SNED1 FCGBP

5.85e-0411622IPR003645
DomainFOLN

SNED1 FCGBP

5.85e-0411622SM00274
DomainCUB

LRP3 ADAMTS13 TMPRSS7

7.25e-0453623PS01180
DomainCUB_dom

LRP3 ADAMTS13 TMPRSS7

8.97e-0457623IPR000859
DomainLdl_recept_b

NID1 LRP1B

9.62e-0414622PF00058
DomainLDLRB

NID1 LRP1B

9.62e-0414622PS51120
DomainEGF_extracell

LRP1B NOTCH1 NOTCH3

1.04e-0360623IPR013111
DomainEGF_2

LRP1B NOTCH1 NOTCH3

1.04e-0360623PF07974
Domain-

MUC17 TMPRSS7

1.11e-03156223.30.70.960
DomainLY

NID1 LRP1B

1.11e-0315622SM00135
DomainLDLR_classB_rpt

NID1 LRP1B

1.11e-0315622IPR000033
DomainLaminin_N

LAMA2 USH2A

1.26e-0316622IPR008211
DomainLAMININ_NTER

LAMA2 USH2A

1.26e-0316622PS51117
DomainLaminin_N

LAMA2 USH2A

1.26e-0316622PF00055
DomainLamNT

LAMA2 USH2A

1.26e-0316622SM00136
DomainCTCK_1

MUC19 SSPOP

1.60e-0318622PS01185
DomainAnkyrin_rpt

TRPM4 INHBC NOTCH1 NOTCH2 NOTCH3

1.76e-03262625IPR002110
DomainSEA

MUC17 TMPRSS7

2.40e-0322622PF01390
DomainSEA

MUC17 TMPRSS7

2.62e-0323622PS50024
DomainSEA_dom

MUC17 TMPRSS7

2.62e-0323622IPR000082
DomainCys_knot_C

MUC19 SSPOP

3.10e-0325622IPR006207
DomainCTCK_2

MUC19 SSPOP

3.10e-0325622PS01225
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC17 ADAMTS13 SSPOP NOTCH1 NOTCH2 NOTCH3

2.46e-0868386M27303
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH1 NOTCH2 NOTCH3

1.80e-075383M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH1 NOTCH2 NOTCH3

3.59e-076383M27068
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC17 ADAMTS13 SSPOP NOTCH1 NOTCH2 NOTCH3

2.07e-06143386M27275
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH1 NOTCH2 NOTCH3

2.94e-0611383M47865
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH1 NOTCH2 NOTCH3

3.91e-0612383M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH1 NOTCH2 NOTCH3

3.91e-0612383M47533
PathwayREACTOME_DISEASES_OF_METABOLISM

MUC17 ADAMTS13 SSPOP GNS NOTCH1 NOTCH2 NOTCH3

4.00e-06250387M27554
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH2 NOTCH3

5.07e-0613383M47423
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH1 NOTCH2 NOTCH3

5.07e-0613383M47534
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH2 NOTCH3

1.43e-0518383M614
PathwayPID_NOTCH_PATHWAY

SSPOP NOTCH1 NOTCH2 NOTCH3

1.84e-0559384M17
PathwayREACTOME_KERATINIZATION

KRTAP3-3 KRT81 KRT83 KRT86 KRTAP27-1 KRT73

2.27e-05217386M27640
PathwayKEGG_DORSO_VENTRAL_AXIS_FORMATION

NOTCH1 NOTCH2 NOTCH3

3.52e-0524383M11190
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

NOTCH1 NOTCH2 NOTCH3

5.05e-0527383M39545
PathwayREACTOME_KERATINIZATION

KRTAP3-3 KRT81 KRT83 KRT86 KRT73

5.30e-05153385MM15343
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH2 NOTCH3

5.65e-0528383M6177
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH3

7.04e-055382MM14733
PathwayREACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

KRT81 KRT83 KRT86 KRT73

8.51e-0587384MM15351
PathwayWP_OSX_AND_MIRNAS_IN_TOOTH_DEVELOPMENT

NOTCH1 NOTCH2 NOTCH3

1.02e-0434383M39390
PathwayWP_NEURAL_CREST_DIFFERENTIATION

PHOX2B NOTCH1 NOTCH2 NOTCH3

1.30e-0497384MM15926
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH3

1.47e-047382MM14734
PathwayWP_NEURAL_CREST_DIFFERENTIATION

PHOX2B NOTCH1 NOTCH2 NOTCH3

1.52e-04101384M39448
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC17 MUC19 ADAMTS13 SSPOP

2.04e-04109384MM15164
PathwayWP_NOTCH_SIGNALING_WP268

NOTCH1 NOTCH2 NOTCH3

2.37e-0445383M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH2 NOTCH3

2.53e-0446383MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH2 NOTCH3

2.70e-0447383M7946
PathwayREACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

KRT81 KRT83 KRT86 KRT73

3.88e-04129384M27649
PathwayBIOCARTA_HES_PATHWAY

NOTCH1 NOTCH2

4.59e-0412382MM1562
PathwayBIOCARTA_HES_PATHWAY

NOTCH1 NOTCH2

4.59e-0412382M22042
PathwayWP_NOTCH_SIGNALING_WP61

NOTCH1 NOTCH2 NOTCH3

5.84e-0461383M39540
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH1 NOTCH2

1.30e-0320382M27881
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH2 NOTCH3

1.38e-0382383MM15922
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC17 MUC19

1.44e-0321382MM15706
PathwayWP_HAIR_FOLLICLE_DEVELOPMENT_CYTODIFFERENTIATION_STAGE_3_OF_3

KRTAP3-3 NOTCH1 NOTCH2

1.64e-0387383M39465
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH3

1.73e-0323382MM14954
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH1 NOTCH3

2.04e-0325382M27880
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

EFNA2 KRTAP3-3 KRT81 KRT83 KRT86 KRT73

2.07e-03502386MM14537
PathwayREACTOME_LAMININ_INTERACTIONS

LAMA2 NID1

2.93e-0330382M27216
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC17 ADAMTS13 SSPOP

3.28e-03111383M27416
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

NOTCH1 NOTCH2 NOTCH3

3.90e-03118383M39852
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH2 NOTCH3

3.99e-03119383M607
PathwayWP_NEOVASCULARIZATION_PROCESSES

NOTCH1 NOTCH3

4.44e-0337382M39506
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS13 SSPOP

4.92e-0339382M27417
PathwayREACTOME_SIGNALING_BY_NOTCH

NOTCH1 NOTCH3

4.92e-0339382MM14604
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS13 SSPOP

4.92e-0339382MM15165
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

NID1 FBN3 CAPN15

6.27e-03140383M587
PathwayPID_PS1_PATHWAY

SSPOP NOTCH1

6.80e-0346382M70
Pubmed

Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate.

NOTCH1 NOTCH2 NOTCH3

6.83e-0936737615640
Pubmed

The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium.

NOTCH1 NOTCH2 NOTCH3

6.83e-0936737918097
Pubmed

Complementary and combinatorial patterns of Notch gene family expression during early mouse development.

NOTCH1 NOTCH2 NOTCH3

6.83e-0936738645602
Pubmed

Expression of Notch1 to -4 and their ligands in renal cell carcinoma: a tissue microarray study.

NOTCH1 NOTCH2 NOTCH3

6.83e-09367321471519
Pubmed

Structure and site of expression of a murine type II hair keratin.

KRT81 KRT83 KRT86

6.83e-0936731372089
Pubmed

Effect of notch1,2,3 genes silicing on NF-κB signaling pathway of macrophages in patients with atherosclerosis.

NOTCH1 NOTCH2 NOTCH3

6.83e-09367327697639
Pubmed

Transient expression of mouse hair keratins in transfected HeLa cells: interactions between "hard" and "soft" keratins.

KRT81 KRT83 KRT86

6.83e-0936731712823
Pubmed

Overlapping but distinct roles for NOTCH receptors in human cardiovascular disease.

NOTCH1 NOTCH2 NOTCH3

6.83e-09367329767458
Pubmed

The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation.

NOTCH1 NOTCH2 NOTCH3

6.83e-0936737698746
Pubmed

Novel KRT83 and KRT86 mutations associated with monilethrix.

KRT81 KRT83 KRT86

6.83e-09367325557232
Pubmed

Comprehensive analysis of keratin gene clusters in humans and rodents.

KRT81 KRT83 KRT86 KRT73

2.25e-081667415085952
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467328061457
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467324145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467320069356
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467319404845
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467328669409
Pubmed

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467310551863
Pubmed

Evolutionary analysis of vertebrate Notch genes.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467311466531
Pubmed

Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467324151014
Pubmed

Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467311401408
Pubmed

Novel MIR143-NOTCH fusions in benign and malignant glomus tumors.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467323999936
Pubmed

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467310194420
Pubmed

NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467318156632
Pubmed

Functional conservation of mouse Notch receptor family members.

NOTCH1 NOTCH2 NOTCH3

2.73e-0846738898100
Pubmed

Notch signalling is linked to epidermal cell differentiation level in basal cell carcinoma, psoriasis and wound healing.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467311978185
Pubmed

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467311459941
Pubmed

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467318184405
Pubmed

Keratins of the human hair follicle.

KRT81 KRT83 KRT86

2.73e-08467315797458
Pubmed

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467315917835
Pubmed

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467323444212
Pubmed

Deregulated expression of Notch receptors in human hepatocellular carcinoma.

NOTCH1 NOTCH2 NOTCH3

2.73e-08467317920003
Pubmed

PERP regulates enamel formation via effects on cell-cell adhesion and gene expression.

KRT81 KRT83 KRT86 LAMA2

4.77e-081967421285247
Pubmed

Notch signaling in bulge stem cells is not required for selection of hair follicle fate.

NOTCH1 NOTCH2 NOTCH3

6.81e-08567319211676
Pubmed

A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons.

NOTCH1 NOTCH2 NOTCH3

6.81e-08567327040987
Pubmed

Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.

NOTCH1 NOTCH2 NOTCH3

6.81e-08567321124806
Pubmed

Functional diversity of notch family genes in fetal lung development.

NOTCH1 NOTCH2 NOTCH3

6.81e-08567315064243
Pubmed

A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.

NOTCH1 NOTCH2 NOTCH3

6.81e-08567321562564
Pubmed

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

NOTCH1 NOTCH2 NOTCH3

6.81e-08567323675950
Pubmed

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

NOTCH1 NOTCH2 NOTCH3

6.81e-08567311101851
Pubmed

Notch expression in developing olfactory neuroepithelium.

NOTCH1 NOTCH2 NOTCH3

6.81e-08567315076712
Pubmed

Chimeric analysis of Notch2 function: a role for Notch2 in the development of the roof plate of the mouse brain.

NOTCH1 NOTCH2 NOTCH3

6.81e-08567312242712
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

NOTCH1 NOTCH2 NOTCH3

6.81e-08567315882997
Pubmed

RBP-L, a transcription factor related to RBP-Jkappa.

NOTCH1 NOTCH2 NOTCH3

1.36e-0766739111338
Pubmed

Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.

NOTCH1 NOTCH2 NOTCH3

1.36e-07667320870902
Pubmed

The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis.

NOTCH1 NOTCH2 NOTCH3

1.36e-07667326062937
Pubmed

ALDH maintains the stemness of lung adenoma stem cells by suppressing the Notch/CDK2/CCNE pathway.

NOTCH1 NOTCH2 NOTCH3

1.36e-07667324671051
Pubmed

Characterization of Notch receptor expression in the developing mammalian heart and liver.

NOTCH1 NOTCH2 NOTCH3

1.36e-07667312244553
Pubmed

Profiling immunohistochemical expression of NOTCH1-3, JAGGED1, cMET, and phospho-MAPK in 100 carcinomas of unknown primary.

NOTCH1 NOTCH2 NOTCH3

1.36e-07667322526456
Pubmed

Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal.

NOTCH1 NOTCH2 NOTCH3

1.36e-07667319503073
Pubmed

Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment.

NOTCH1 NOTCH2 NOTCH3

1.36e-07667319573812
Pubmed

Expression of Deltex1 during mouse embryogenesis: comparison with Notch1, 2 and 3 expression.

NOTCH1 NOTCH2 NOTCH3

1.36e-07667311731257
Pubmed

Aberrant expression of Notch signaling molecules in patients with immune thrombocytopenic purpura.

NOTCH1 NOTCH2 NOTCH3

1.36e-07667319603167
Pubmed

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.

NOTCH1 NOTCH2 NOTCH3

1.36e-07667318299578
Pubmed

Mouse Serrate-1 (Jagged-1): expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4.

NOTCH1 NOTCH2 NOTCH3

1.36e-0766739108364
Pubmed

Delta-notch signaling in odontogenesis: correlation with cytodifferentiation and evidence for feedback regulation.

NOTCH1 NOTCH2 NOTCH3

1.36e-0766739882480
Pubmed

Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.

NOTCH1 NOTCH2 NOTCH3

1.36e-07667315019995
Pubmed

Notch controls the magnitude of T helper cell responses by promoting cellular longevity.

NOTCH1 NOTCH2 NOTCH3

1.36e-07667322615412
Pubmed

Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.

NOTCH1 NOTCH2 NOTCH3

1.36e-07667321991352
Pubmed

Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family.

NOTCH1 NOTCH2 NOTCH3

1.36e-07667327460529
Pubmed

Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development.

AIRE NOTCH1 NOTCH2 NOTCH3

1.82e-072667432467237
Pubmed

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development.

NOTCH1 NOTCH2 NOTCH3

2.38e-07767310383933
Pubmed

Human ligands of the Notch receptor.

NOTCH1 NOTCH2 NOTCH3

2.38e-07767310079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

NOTCH1 NOTCH2 NOTCH3

2.38e-07767312846471
Pubmed

Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis.

NOTCH1 NOTCH2 NOTCH3

2.38e-07767311518718
Pubmed

Differentiation of CD11c+ CX3CR1+ cells in the small intestine requires Notch signaling.

NOTCH1 NOTCH2 NOTCH3

2.38e-07767324711412
Pubmed

Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis.

NOTCH1 NOTCH2 NOTCH3

2.38e-07767316169548
Pubmed

Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.

NOTCH1 NOTCH2 NOTCH3

3.80e-07867322156581
Pubmed

P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis.

NOTCH1 NOTCH2 NOTCH3

3.80e-07867322652674
Pubmed

Notch1 and Jagged1 expression by the developing pulmonary vasculature.

NOTCH1 NOTCH2 NOTCH3

3.80e-07867312242716
Pubmed

Expression of Hairy/Enhancer of Split genes, Hes1 and Hes5, during murine nephron morphogenesis.

NOTCH1 NOTCH2 NOTCH3

3.80e-07867315465493
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

NOTCH1 NOTCH2 NOTCH3

3.80e-0786739858718
Pubmed

Notch/Delta expression in the developing mouse lung.

NOTCH1 NOTCH2 NOTCH3

3.80e-07867311044610
Pubmed

ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation.

NID1 NOTCH1 NOTCH2 NOTCH3

3.80e-073167422274697
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

NOTCH1 NOTCH2 NOTCH3

5.69e-07967311118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

NOTCH1 NOTCH2 NOTCH3

5.69e-07967316245338
Pubmed

Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

NOTCH1 NOTCH2 NOTCH3

5.69e-07967312370315
Pubmed

Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor.

NOTCH1 NOTCH2 NOTCH3

5.69e-07967317573339
Pubmed

Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity.

NOTCH1 NOTCH2 NOTCH3

5.69e-07967318507503
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

NOTCH1 NOTCH2 NOTCH3

8.12e-071067323665443
Pubmed

Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer.

NOTCH1 NOTCH2 NOTCH3

8.12e-071067328489825
Pubmed

gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis.

NOTCH1 NOTCH2 NOTCH3

8.12e-071067315525534
Pubmed

Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle.

NOTCH1 NOTCH2 NOTCH3

8.12e-071067324015274
Pubmed

Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.

NOTCH1 NOTCH2 NOTCH3

8.12e-071067333915108
Pubmed

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.

NOTCH1 NOTCH2 NOTCH3

1.12e-061167316607638
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

NOTCH1 NOTCH2 NOTCH3

1.12e-061167315499562
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

NOTCH1 NOTCH2 NOTCH3

1.12e-061167310878608
Pubmed

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.

NOTCH1 NOTCH2 NOTCH3

1.12e-06116739187150
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

NOTCH1 NOTCH2 NOTCH3

1.12e-061167312866128
Pubmed

Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium.

NOTCH1 NOTCH2 NOTCH3

1.48e-061267310952889
Pubmed

Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain.

KRT81 KRT83 KRT86

1.48e-061267310692104
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

NOTCH1 NOTCH2 NOTCH3

1.48e-061267315465494
Pubmed

Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development.

NOTCH1 NOTCH2 NOTCH3

1.48e-061267332147304
Pubmed

Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression.

NOTCH1 NOTCH2 NOTCH3

1.48e-061267314732396
Pubmed

A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.

NOTCH1 NOTCH2 NOTCH3

1.93e-061367332929274
Pubmed

Notch signaling coordinates the patterning of striatal compartments.

NOTCH1 NOTCH2 NOTCH3

1.93e-061367316120638
Pubmed

Jagged1 is Essential for Radial Glial Maintenance in the Cortical Proliferative Zone.

NOTCH1 NOTCH2 NOTCH3

1.93e-061367331202705
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

NOTCH1 NOTCH2 NOTCH3

1.93e-061367311578869
Pubmed

Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.

NOTCH1 NOTCH2 NOTCH3

1.93e-061367320558824
Pubmed

Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells.

NOTCH1 NOTCH2 NOTCH3

1.93e-061367323132245
Pubmed

Cell-fate transition and determination analysis of mouse male germ cells throughout development.

NOTCH1 NOTCH2 NOTCH3

2.45e-061467334824237
InteractionNTN5 interactions

LRP1B NOTCH1 NOTCH2 NOTCH3

8.79e-0724634int:NTN5
InteractionEGFL7 interactions

KLRG2 LRP3 NOTCH1 NOTCH2 NOTCH3

4.22e-0677635int:EGFL7
InteractionKRT25 interactions

KRT81 KRT83 KRT86 KRT73

4.22e-0635634int:KRT25
InteractionIGSF5 interactions

NOTCH1 NOTCH2 NOTCH3

1.03e-0514633int:IGSF5
InteractionZNF407 interactions

RNF4 ZNF407 NOTCH2

1.03e-0514633int:ZNF407
InteractionHOXA1 interactions

OIT3 RNF4 KRTAP3-3 KRT81 KRT83 BAHD1 NOTCH1 NOTCH3

1.46e-05356638int:HOXA1
InteractionMOCS3 interactions

RIT1 ZNF252P-AS1 EFNA2 OIT3

1.52e-0548634int:MOCS3
InteractionMAML2 interactions

NOTCH1 NOTCH2 NOTCH3

1.92e-0517633int:MAML2
InteractionJAG2 interactions

EFNA2 OIT3 NOTCH1 NOTCH2 NOTCH3

2.42e-05110635int:JAG2
InteractionMAML3 interactions

NOTCH1 NOTCH2 NOTCH3

3.20e-0520633int:MAML3
InteractionCASR interactions

NOTCH1 NOTCH2 NOTCH3

4.30e-0522633int:CASR
InteractionZNF275 interactions

RNF4 BAHD1 NOTCH2

4.93e-0523633int:ZNF275
InteractionZNF696 interactions

OIT3 RNF4 LRP3 NOTCH2

6.08e-0568634int:ZNF696
InteractionKRT36 interactions

KRT81 KRT83 KRT86 KRT73

8.47e-0574634int:KRT36
InteractionIGFL3 interactions

LRP1B NOTCH1 NOTCH2 NOTCH3

8.92e-0575634int:IGFL3
InteractionZNF707 interactions

RNF4 NOTCH1 NOTCH2 NOTCH3

1.09e-0479634int:ZNF707
CytobandEnsembl 112 genes in cytogenetic band chr12q13

INHBC KRT81 KRT83 KRT86 KRT73 AMIGO2

3.67e-05423676chr12q13
Cytoband12q13

KRT81 KRT83 KRT86

1.58e-047167312q13
CytobandEnsembl 112 genes in cytogenetic band chr19q13

TRPM4 FCGBP IRF2BP1 SIGLEC14 LRP3 SIGLEC5 IGFLR1

1.75e-031192677chr19q13
GeneFamilyKeratins, type II

KRT81 KRT83 KRT86 KRT73

4.68e-0727434609
GeneFamilyLow density lipoprotein receptors

LRP3 LRP1B

4.24e-0413432634
GeneFamilyCD molecules|Mucins

MUC17 MUC19

1.13e-0321432648
GeneFamilyCD molecules|C2-set domain containing|Sialic acid binding Ig like lectins

SIGLEC14 SIGLEC5

2.01e-0328432745
CoexpressionNABA_MATRISOME

SNED1 HGFAC OIT3 MUC17 INHBC MBL2 MUC19 LAMA2 NID1 CST7 ADAMTS13 HTRA4 USH2A SSPOP FBN3

2.32e-0810266515M5889
CoexpressionNABA_ECM_GLYCOPROTEINS

SNED1 OIT3 LAMA2 NID1 USH2A SSPOP FBN3

5.67e-07196657M3008
CoexpressionNABA_MATRISOME

SNED1 HGFAC OIT3 MUC17 INHBC MBL2 MUC19 LAMA2 NID1 CST7 ADAMTS13 HTRA4 SSPOP

9.56e-0710086513MM17056
CoexpressionNABA_CORE_MATRISOME

SNED1 OIT3 LAMA2 NID1 USH2A SSPOP FBN3

5.37e-06275657M5884
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

NOTCH1 NOTCH2 NOTCH3

7.97e-0616653MM1296
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

NOTCH1 NOTCH2 NOTCH3

7.97e-0616653M2207
CoexpressionHALLMARK_NOTCH_SIGNALING

NOTCH1 NOTCH2 NOTCH3

6.86e-0532653M5903
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-ILC_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

KRT81 KRT83 KRT86 SSPOP CAPN15 PDZD2

3.85e-07187676f31d865ce2a21bdf64dbe29ee3e4505ab482604a
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Duct|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FCGBP KRT81 KRT83 LRP3 ITPRID1 FBN3

4.92e-07195676fdbb4abc0c79a6aeace71bfa5a5c5576ca39d758
ToppCellSigmoid-(0)_NK_cell|Sigmoid / shred on region, Cell_type, and subtype

KRT81 KRT86 IRF8 C10orf95 CST7 ADAMTS13

5.54e-071996765be944da7a6c5f6076ed508a64f77d90836becd7
ToppCellSigmoid-NK_cell-NK|Sigmoid / Region, Cell class and subclass

KRT81 KRT86 IRF8 C10orf95 CST7 ADAMTS13

5.54e-071996765aa943ef7a1764ce4e95a7163aaabe2ee89eb870
ToppCellSigmoid-NK_cell|Sigmoid / Region, Cell class and subclass

KRT81 KRT86 IRF8 C10orf95 CST7 ADAMTS13

5.54e-07199676653965a8bb09abcab7d275b01d361b7b4e3fdd58
ToppCellSigmoid-(0)_NK_cell-(00)_NK|Sigmoid / shred on region, Cell_type, and subtype

KRT81 KRT86 IRF8 C10orf95 CST7 ADAMTS13

5.54e-07199676689e8675d2d40cfb1bd200767a35dcc6664214d9
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FCGBP KRT81 KRT86 MUC19

3.82e-0670674986c7a1002a4ffd3a246495bedde2997ffdc2c9d
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FCGBP KRT81 KRT86 MUC19

3.82e-0670674c0330216305491d7d57cdbea0ae3cb8e9092c8e3
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P3|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FCGBP KRT81 KRT86 MUC19

3.82e-067067486dde790fcdaec2095e2256463953077811145d2
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FCGBP KRT81 KRT86 MUC19

3.82e-0670674e604660b2efbc03e21806dcaecf7a72321673ae2
ToppCell10x5'-GI_small-bowel-Lymphocytic_NK-NK_CD56bright_CD16-|GI_small-bowel / Manually curated celltypes from each tissue

KRT81 KRT83 KRT86 IRF8 CST7

4.87e-0616467536e64e4f717dd59b352c20ff9742ca1e232342bb
ToppCell3'_v3-GI_small-bowel-Lymphocytic_NK-NK_CD56bright_CD16-|GI_small-bowel / Manually curated celltypes from each tissue

KRT81 KRT86 IRF8 NID1 CST7

5.32e-061676757ff186b2bed3b0de93addb3b0ae5a2c6e44ddfb2
ToppCell367C-Lymphocytic-NK_cells-NK_cell_A|367C / Donor, Lineage, Cell class and subclass (all cells)

KRT81 KRT86 IRF8 CST7 KRT73

7.66e-06180675023c83f0c9d0280983c6fd28ecf04bfa6b1b89e2
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMA2 NID1 NOTCH2 NOTCH3 PDZD2

9.95e-06190675106862ef44fcaa0971c3ba0147d13eb08015ca77
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LAMA2 NID1 NOTCH2 NOTCH3 PDZD2

9.95e-06190675979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCellP03-Mesenchymal-developing_mesenchymal_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LAMA2 NID1 NOTCH2 NOTCH3 PDZD2

1.05e-05192675063e119c4b58957643908f667e6cfd6f7517fd03
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SNED1 LAMA2 NID1 RIPOR3 CBARP

1.07e-05193675261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KRT81 KRT83 KRT86 CST7 KRT73

1.16e-05196675609959609ab1870c562cefca0fd49e0d701d1e5b
ToppCellBronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IL17REL IRF8 CST7 IGFLR1 CRIP3

1.19e-0519767581dd7f9318f0ba175352e5156c24772427e0b34f
ToppCelldistal-3-Hematologic-Myeloid_Dendritic_Type_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IRF8 CST7 SLC35E4 IGFLR1 CRIP3

1.21e-05198675b21227c7366ef79b36048509a91d2d35fd5e4956
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

LAMA2 NID1 NOTCH2 NOTCH3 PDZD2

1.27e-05200675bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SIGLEC14 CBARP USH2A AMIGO2

4.56e-051316741823cab28fab40486247ca92104267b1e370bdc1
ToppCelldroplet-Tongue-Unstain-18m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRTAP3-3 KRT81 KRT86 NOTCH2

4.84e-05133674f7d0763b5eec2db33044d6850fd57462494038c1
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|356C / Donor, Lineage, Cell class and subclass (all cells)

C10orf143 KRT81 KRT86 CST7

8.34e-051536745fb7d92cddc816c64071465e955ed0ea3bb45316
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 NID1 NOTCH3 PDZD2

9.22e-05157674bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCell368C-Lymphocytic-NK_cells|368C / Donor, Lineage, Cell class and subclass (all cells)

KRT81 KRT86 AIRE CST7

9.22e-05157674ef5c0ace4cd500b6cc50fb7076298f3d3543b40c
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SIGLEC5 IGFLR1 PRAG1 GNS

9.45e-051586746811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 LAMA2 USH2A LRP1B

9.92e-05160674c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell367C-Lymphocytic-ILC|367C / Donor, Lineage, Cell class and subclass (all cells)

C10orf143 KRT81 KRT86 CST7

9.92e-05160674f70ec054b6d51c1565e4a257cbe3c9537c0eb09f
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 LAMA2 USH2A LRP1B

9.92e-0516067425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF19B RIPOR3 CST7 TMPRSS7

1.02e-0416167452556b89808e551540f33a13f57417a6696c2438
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF19B RIPOR3 CST7 TMPRSS7

1.02e-0416167454f156cf2bd5a6ba9a78ec4e3ee28b89998aec2e
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF19B RIPOR3 CST7 TMPRSS7

1.02e-04161674242891be849a4398fe8bea44875ae1ba57950944
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Calb2-Excitatory_Neuron.Slc17a7.Calb2-Vgll3_(Dentate_hilum?)|Hippocampus / BrainAtlas - Mouse McCarroll V32

FCGBP AIRE PABPC1L

1.02e-0460673aa75fef294803ec6396c7d2c1f51d52bc4a5b43f
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Calb2-Excitatory_Neuron.Slc17a7.Calb2-Vgll3_(Dentate_hilum?)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

FCGBP AIRE PABPC1L

1.02e-0460673069fbabfd0e48e5809ff01a026439fd0bd017779
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-ILC3|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KRT81 KRT83 KRT86 PDZD2

1.07e-0416367400e791358a7eb6c3e95f87afe22153845012e4a1
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFNA2 SLC35E4 ADAMTS13 IGFLR1

1.09e-04164674b895674ed2df87db8fbfb30b7e31620945588491
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KRT81 KRT86 IRF8 SIGLEC5

1.17e-0416767499db8871c62336bd215efb65e969783d2b6003b0
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KRT81 KRT86 CST7 CBARP

1.20e-041686742765d98f0b7f6861d662937535e051d41dba3500
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP20DC IRF8 KLRG2 SSPOP

1.22e-041696749c9bb1b32fc6e22359424a262178906c3954415d
ToppCell10x3'2.3-week_17-19-Myeloid_DC-DC-tDC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

IRF8 IGFLR1 LRP1B AMIGO2

1.28e-04171674b327fb7813a3cdae06c8a4f8a0c256e9a20132f6
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGBP KRT81 KRT86 CST7

1.31e-04172674e3a8891694343b6b01e80a200ae338d24797e417
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID1 HTRA4 NOTCH3 AMIGO2

1.34e-041736742415b6ff49f334da570577d4e93484d024a3dbd5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID1 HTRA4 NOTCH3 AMIGO2

1.34e-041736742acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SNED1 LAMA2 PRAG1 PDZD2

1.37e-041746749cc7251661ea2b1565eef1dfb8cf6dec3ade13d4
ToppCell(03)_Secretory-(0)_uninjured|(03)_Secretory / shred by cell type and Timepoint

ARFGEF3 FCGBP GNS NOTCH2

1.37e-04174674ebdddb5091afcc49ab533c890f260f709880c5f9
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_Tfh|metastatic_Brain / Location, Cell class and cell subclass

KRT81 KRT86 CST7 SLC35E4

1.40e-04175674b732c6a423c28856211002107d8c611dcfb6f265
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 LAMA2 USH2A LRP1B

1.40e-04175674887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3_(Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FCGBP MUC17 KRT73

1.41e-0467673e53dfc288c943656a0b064afe593ea2101d75437
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3_(Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FCGBP MUC17 KRT73

1.41e-04676731841cee311a4b1b802c9e872793435afb730592f
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 LAMA2 USH2A LRP1B

1.43e-04176674c6484334187f64cd00cd35e77d8ae436556b4260
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC TRPM4 OIT3 CST7

1.46e-04177674c1f838e425ebb04482829b1957e3c1347127e6de
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC TRPM4 OIT3 CST7

1.49e-04178674cc0382b0ee1e6c76522e2c86ad1425c45debab5d
ToppCellPND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OIT3 RNF19B RIPOR3 TMPRSS7

1.49e-041786749e1f2596fcea5b79cc50b58d83706bb8605e224f
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

KRT86 SLC35E4 NOTCH2 NOTCH3

1.49e-041786749a3581a0158dfa5a1cc942f8c532afb5e38b272a
ToppCell21-Trachea-Immune-Hematopoietic,_Natural_Killer_Cell|Trachea / Age, Tissue, Lineage and Cell class

KRT81 KRT86 IRF8 CST7

1.49e-04178674d2e1f6b7933b7da2682393e5ff5e03cdd8f64761
ToppCellPND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OIT3 RNF19B RIPOR3 TMPRSS7

1.49e-04178674aa659bd283c4dfbe292cd8698bbf6b1999ca3314
ToppCellPND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OIT3 RNF19B RIPOR3 TMPRSS7

1.49e-04178674bf1d273802a4f42e52ea1bd2a0cae2039559c093
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-T_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KRT81 KRT83 KRT86 CST7

1.53e-04179674e717c0079b788a3703c0a450922bd5a2bdc322a0
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMA2 NID1 NOTCH3 PDZD2

1.53e-0417967456db12467b445f2b8ef92af50779eeab10413eb2
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IRF2BP1 PABPC1L SLC35E4 PHOX2B

1.56e-04180674c72f15763ba707189e29c85db533557f01c7fdb1
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC TRPM4 CST7 TMPRSS7

1.56e-0418067441e8155cc7b3dac9d496e4077845ca6af1591a5c
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

NID1 RIPOR3 NOTCH3 PDZD2

1.59e-0418167433cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SNED1 MUC19 LRP1B PDZD2

1.59e-041816749de2f2cc5f02e0ca599c9e0d2cb1e1e4b5aac112
ToppCellControl_saline-Hematopoietic_Myeloid-Dendritic_cells-mDC|Control_saline / Treatment groups by lineage, cell group, cell type

IRF8 AIRE CST7 NOTCH2

1.59e-04181674818ac31a718e9b29feb4c4eecbc339e6af45254a
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-NK_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KRT81 KRT83 KRT86 CST7

1.63e-04182674feda21c92d30848de70c8b404eaabbca3f5e894d
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 NID1 NOTCH3 PDZD2

1.66e-041836748a799807fbf24456a9811e0c64068187940a2f71
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 USH2A LRP1B SSPOP

1.70e-041846742cbed6462fea2622871bb7e49b0df3d984239281
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 NID1 NOTCH3 PDZD2

1.70e-04184674689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3|lymph-node_spleen / Manually curated celltypes from each tissue

ARFGEF3 KRT81 KRT86 PDZD2

1.70e-04184674479e60f76c191253e23699c9dd7ef7efc08c59ad
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 USH2A LRP1B SSPOP

1.70e-04184674ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 USH2A LRP1B SSPOP

1.70e-041846742b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 NID1 NOTCH3 PDZD2

1.70e-04184674327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell367C-Lymphocytic-NK_cells-NK_cell_A|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KRT81 IRF8 CST7 KRT73

1.73e-0418567425781cf68e693e97dc1885e2879ab24fa946b51e
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC TRPM4 OIT3 CST7

1.73e-041856745527fa9d2e0b2f3607602e18ba94de4e9bbc6824
ToppCelldroplet-Tongue-Unstain-18m-Epithelial-filiform|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRTAP3-3 KRT81 KRT86 KRTAP27-1

1.73e-04185674e0c9e92e35fb24351f5347a0768e6aab5add8775
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

RIPOR3 ITPRID1 NOTCH3 PDZD2

1.73e-04185674ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 NID1 NOTCH3 PDZD2

1.77e-04186674888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA2 NID1 RIPOR3 LRP1B

1.77e-041866747582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARFGEF3 TMPRSS7 PHOX2B AMIGO2

1.84e-04188674c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMA2 NID1 NOTCH3 PDZD2

1.84e-04188674a906c29e3fda22eecfec3e5cac706c417bf2b7a4
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-conventional_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IRF8 CST7 IGFLR1 CRIP3

1.84e-04188674c39083b8020ae507246959abbb299d78bcd14042
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-conventional_dendritic_cell-DC1_(conventional_dendritic_cell)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IRF8 CST7 IGFLR1 CRIP3

1.84e-041886746e7a678474715f035cc13a0e226a937688f54121
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-conventional_dendritic_cell-DC1_(conventional_dendritic_cell)-DC1_L.1.2.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IRF8 CST7 IGFLR1 CRIP3

1.84e-041886748862ecb87fc9b95eccc527387f2332dcc92cfdc3
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KRT81 KRT83 KRT86 CST7

1.88e-041896745c85656f555d91ecc9540faa67717694a4aef92f
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LAMA2 NID1 NOTCH3 PDZD2

1.88e-0418967426cfe5b7e7f477f225f4e9f25f983f432f01e183
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRPM4 FCGBP CST7 CRIP3

1.88e-04189674e97c64609b1f8158d750edb869df56e5bd10538b
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

KRT81 KRT83 KRT86 CST7

1.88e-04189674723c57f278919e8251d56b3d19411f9088319450
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK-T_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

KRT81 KRT83 KRT86 CST7

1.88e-04189674960374f5fb278659500a7c948c3068a95dd62eb0
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMA2 NID1 NOTCH3 PDZD2

1.88e-04189674ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCellPCW_07-8.5-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_natural_killer_[NK]_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KRT81 KRT86 CST7 KRT73

1.92e-041906745c6801046ab88aad76697984342319872a8f9e38
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LAMA2 NID1 NOTCH3 PDZD2

1.92e-041906742ab604d35456beba71c25511e0f819000e6642d2
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EFNA2 IGFLR1 CRIP3 LRP1B

1.92e-041906744b25d49f033bbd326b47cf5602af3f0262cfc367
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT81 KRT83 KRT86 CST7

1.92e-04190674ce049630ed69d31f00acbc1b5b0896efc592121f
ToppCelldroplet-Tongue-nan-3m-Epithelial-filiform|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRTAP3-3 KRT81 KRT83 KRT86

1.92e-04190674251e3a33041023bfc4b547c7eb68cfb8f421636f
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMA2 NID1 NOTCH3 PDZD2

1.92e-041906747e4d80a3a7f83b6a50f1d0fe82fb6c242c39d5b0
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMA2 NID1 NOTCH3 PDZD2

1.92e-041906741004e89d99c9d46c78b7d3532d8d4aadb81a96fd
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

SNED1 LAMA2 NID1 RIPOR3

1.92e-0419067412992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMA2 NID1 NOTCH3 PDZD2

1.92e-04190674951e067d14412db67dc3babcdf61e41717d7b429
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMA2 NID1 NOTCH3 PDZD2

1.92e-041906747fec459cd2ad12c2923a03d098289337c0a4c1d3
Drugtebuquine

KRT81 KRT83

7.78e-062642CID000071991
Drug3,5-di-O-galloylquinic acid

KRT81 KRT83

7.78e-062642CID000460896
Drugmelicopicine

KRT81 KRT83

7.78e-062642CID000101253
DrugATBI

KRT81 KRT83 KRT86

1.68e-0518643CID000505862
DrugTropine [120-29-6]; Up 200; 28.4uM; MCF7; HT_HG-U133A

IRF2BP1 RNF19B NID1 C10orf95 ZNF407 CAPN15

2.03e-051996463569_UP
Drugsulfonamide-3

KRT81 KRT83

2.33e-053642CID009847197
DrugA25152

NID1 IGFLR1 NOTCH2 NOTCH3

2.80e-0562644CID000002956
Drugpyriproxyfen

KRT81 KRT83 KRT86

3.60e-0523643CID000091753
Druglactucin

KRT81 KRT83

4.65e-054642CID000442266
DrugLactupicrin

KRT81 KRT83

4.65e-054642CID000174880
Druggamma-secretase inhibitor I

NOTCH2 NOTCH3

4.65e-054642CID011754711
DrugSureCN2313095

HGFAC NID1 NOTCH2 NOTCH3

6.26e-0576644CID011840973
Drugdihydralazine

KRT81 KRT83 AIRE

7.35e-0529643CID000010230
DiseaseBeaded hair

KRT81 KRT83 KRT86

9.28e-093633cv:C0546966
DiseaseMONILETHRIX

KRT81 KRT83 KRT86

9.28e-093633158000
Diseasemonilethrix (is_implicated_in)

KRT81 KRT83 KRT86

9.28e-093633DOID:0050472 (is_implicated_in)
DiseaseMonilethrix

KRT81 KRT83 KRT86

3.70e-084633C0546966
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

3.23e-077633DOID:299 (implicated_via_orthology)
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

3.23e-077633DOID:3620 (implicated_via_orthology)
Diseasehair disease (is_implicated_in)

KRT81 KRT86

4.49e-062632DOID:421 (is_implicated_in)
DiseaseMalignant neoplasm of skin

AIRE NOTCH1 NOTCH2 NOTCH3

7.86e-0659634C0007114
DiseaseSkin Neoplasms

AIRE NOTCH1 NOTCH2 NOTCH3

7.86e-0659634C0037286
Diseasebrain cancer (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

2.33e-0526633DOID:1319 (implicated_via_orthology)
Diseasecolorectal cancer (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

3.61e-0530633DOID:9256 (implicated_via_orthology)
Diseaseintestinal cancer (implicated_via_orthology)

NOTCH1 NOTCH2 NOTCH3

4.40e-0532633DOID:10155 (implicated_via_orthology)
DiseaseSquamous cell carcinoma of esophagus

DIDO1 NOTCH1 NOTCH2 NOTCH3

5.19e-0595634C0279626
DiseaseErythrokeratodermia variabilis

TRPM4 KRT83

9.36e-057632C0265961
Diseasedolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 measurement

SIGLEC14 SIGLEC5

2.00e-0410632EFO_0801544
DiseaseBladder Neoplasm

RALGPS1 LAMA2 NOTCH1 NOTCH2

2.33e-04140634C0005695
DiseaseMalignant neoplasm of urinary bladder

RALGPS1 LAMA2 NOTCH1 NOTCH2

2.39e-04141634C0005684
Diseasesialic acid-binding Ig-like lectin 14 measurement

SIGLEC14 SIGLEC5

2.92e-0412632EFO_0008284
DiseaseNeoplasm of uncertain or unknown behavior of bladder

NOTCH1 NOTCH2

4.63e-0415632C0496930
DiseaseBenign neoplasm of bladder

NOTCH1 NOTCH2

4.63e-0415632C0154017
DiseaseCarcinoma in situ of bladder

NOTCH1 NOTCH2

4.63e-0415632C0154091
DiseaseSjogren's syndrome (implicated_via_orthology)

MUC19 AIRE

5.98e-0417632DOID:12894 (implicated_via_orthology)
DiseaseGlioblastoma

NOTCH1 NOTCH2 NOTCH3

6.53e-0479633C0017636
DiseaseCarcinoma of bladder

NOTCH1 NOTCH2

6.71e-0418632C0699885
DiseaseGiant Cell Glioblastoma

NOTCH1 NOTCH2 NOTCH3

7.81e-0484633C0334588
Diseasealpha-tocopherol measurement

CFAP20DC USH2A

8.32e-0420632EFO_0007898
DiseaseCarcinoma, Pancreatic Ductal

NOTCH1 NOTCH3

1.20e-0324632C0887833
DiseaseCerebral Astrocytoma

NOTCH1 NOTCH2

1.30e-0325632C0750935
DiseaseIntracranial Astrocytoma

NOTCH1 NOTCH2

1.30e-0325632C0750936
DiseasePilocytic Astrocytoma

NOTCH1 NOTCH2

1.30e-0325632C0334583
DiseaseAstrocytoma

NOTCH1 NOTCH2

1.30e-0325632C0004114
DiseaseJuvenile Pilocytic Astrocytoma

NOTCH1 NOTCH2

1.30e-0325632C0280783
DiseaseDiffuse Astrocytoma

NOTCH1 NOTCH2

1.30e-0325632C0280785
DiseaseGrade I Astrocytoma

NOTCH1 NOTCH2

1.30e-0325632C1704230
DiseaseSubependymal Giant Cell Astrocytoma

NOTCH1 NOTCH2

1.30e-0325632C0205768
DiseaseMixed oligoastrocytoma

NOTCH1 NOTCH2

1.30e-0325632C0547065
DiseaseChildhood Cerebral Astrocytoma

NOTCH1 NOTCH2

1.30e-0325632C0338070
DiseaseGemistocytic astrocytoma

NOTCH1 NOTCH2

1.41e-0326632C0334581
DiseaseProtoplasmic astrocytoma

NOTCH1 NOTCH2

1.41e-0326632C0334580
DiseaseFibrillary Astrocytoma

NOTCH1 NOTCH2

1.41e-0326632C0334582
DiseaseAnaplastic astrocytoma

NOTCH1 NOTCH2

1.52e-0327632C0334579
DiseaseGlioblastoma Multiforme

NOTCH1 NOTCH2 NOTCH3

1.75e-03111633C1621958

Protein segments in the cluster

PeptideGeneStartEntry
GCPGSGLCVLPSGSV

CBARP

651

Q8N350
VTVGPGASGVCPTAC

AMIGO2

31

Q86SJ2
CGPGSRLDPSGTFCL

FBN3

791

Q75N90
PPTCGSASCRNTLGG

FBN3

2576

Q75N90
GPRSPCSRSCGGGVV

ADAMTS13

391

Q76LX8
PGTGLRCRSCSGDVT

AIRE

466

O43918
SSGLESPTGPCICSL

RALGPS1

411

Q5JS13
NTPVASSCSVCGGPR

CAPN15

156

O75808
CCLVLSTTGGPSPDT

CST7

11

O76096
APSPCVNGGTCRQTG

NOTCH2NLB

226

P0DPK3
APSPCVNGGTCRQTG

NOTCH2

226

Q04721
PCQNGGTCRPTGDVT

NOTCH1

226

P46531
RCLNGGTCISGPRSP

NOTCH1

1356

P46531
GTCISGPRSPTCLCL

NOTCH1

1361

P46531
GTCVPSVLGRPTCSC

LRP1B

4261

Q9NZR2
LRCGEASPPSAACGS

MAP1S

586

Q66K74
FGSVALGSVCPSLCP

KRT73

86

Q86Y46
FPTPPTSRCTCVTGG

IL17REL

291

Q6ZVW7
LGTGPRGTSLECTVC

ITPRID1

726

Q6ZRS4
TVATPRAGGQCPACG

INHBC

16

P55103
TGGGSCCVPTARRPL

INHBC

311

P55103
RSGGVCGPSPPCITT

KRT86

66

O43790
TTCPEGCRLSLSQPG

IRF8

221

Q02556
TCAPGTVLGPDRQTC

OIT3

166

Q8WWZ8
SVELRPCPSGQTGTC

MUC19

851

Q7Z5P9
SGHCCPGGSRESPVT

PDZD2

1411

O15018
TPGSRTCRCPDNTLG

NID1

1226

P14543
VNGRAICTCPPGFTG

NOTCH3

371

Q9UM47
LCPGGTFPCSGARST

LRP3

211

O75074
TCPAVIACSSPGING

MBL2

31

P11226
SRGCSVPTGPATTIC

KRTAP3-3

6

Q9BYR6
PVTGFCTCRPGATGR

LAMA2

1541

P24043
TQTTGPSGVGCCTPG

PABPC1L

486

Q4VXU2
ATGTTVCACPPGFAG

HGFAC

261

Q04756
GFPSTCGCPTLGGAV

HTRA4

101

P83105
AEGSAGSPGSPTCCR

KLRG2

206

A4D1S0
PGGGSLVCTPASCGL

FCGBP

2036

Q9Y6R7
TCRPSGGSLGCVAVG

FCGBP

3636

Q9Y6R7
GCSCTAPALSGPVAR

ARFGEF3

306

Q5TH69
AELCSPCGGGAVTPT

IGFLR1

86

Q9H665
LSPCPASCGSGVVTT

DIDO1

946

Q9BTC0
PLSVTHAGTTCGGCP

BAHD1

456

Q8TBE0
TFTGETSLCPGCGEP

CRIP3

116

Q6Q6R5
QSCSGPTCRTPGVFD

GNS

511

P15586
CSSPGGCRLFLSTIP

EFNA2

191

O43921
GVEPTCCVTGGSQLP

KRTAP27-1

191

Q3LI81
SGTGATPGAPLCCTL

IRF2BP1

491

Q8IU81
RSGGVCGPSPPCITT

KRT83

71

P78385
VCGDLCVSGSRPVTG

KRT83

441

P78385
TPTVPRTTTCFGDGC

MUC17

4126

Q685J3
SAGSCVRIPSGSCRP

SERHL

186

Q9NQF3
GTLPGTICDPISGQC

USH2A

906

O75445
VPISLCRGGGCGVST

RNF19B

436

Q6ZMZ0
GSTDGCVCPPGTVLL

SSPOP

951

A2VEC9
RSCSSLAPGDTTCPG

SSPOP

2856

A2VEC9
SGRPTRLSCSLPGSC

SIGLEC5

156

O15389
TVSDPCFSSPCGGRG

SNED1

866

Q8TER0
PTTCLSPTGRRCGSC

CFAP20DC

476

Q6ZVT6
SCAGSCGARTAPTPA

C10orf95

186

Q9H7T3
SSAQPCPRCIAGESG

C10orf143

86

A0A1B0GUT2
RPVGSCCSSPAGLSR

RIT1

6

Q92963
GCTGPGRVLSCPATT

RIPOR3

696

Q96MK2
PRGCRLPSISSTTCG

SPATS1

11

Q496A3
SQPCPVGSFRCSSGL

TMPRSS7

481

Q7RTY8
ATGLRPSGTVSCPIC

RNF4

121

P78317
GCPGVTPSRCLGLTG

PRAG1

381

Q86YV5
TPCPVTGTGGTAVSR

FP248

96

Q71RG6
CSFPVTSLPALGGVC

ZNF252P-AS1

6

Q0IIN9
CSLAGEFRTPPTGCG

SLC35E4

176

Q6ICL7
TVGGTCLPNALSPSC

ZNF407

121

Q9C0G0
GCPSLTPGSCSLGTL

PHOX2B

56

Q99453
SGRPTRLSCSLPGSC

SIGLEC14

156

Q08ET2
DSTDPGGTLCQCGRP

TRPM4

26

Q8TD43
CALCPLVGGTSTGGP

TRIM56

101

Q9BRZ2
RSGGVCGPSPPCITT

KRT81

66

Q14533
VCGDLCVSGSRPVTG

KRT81

436

Q14533