Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF771 KLF16 ZNF668 KLF8 ZNF845 ZNF526 ZNF676 ZNF773 ZNF142 ZNF219 WIZ KLF6 ZNF658 ZNF559 MAX ZBTB8B ZNF611 ZNF620 ZNF398 ZFHX2 ZBTB8A KLF3 ZNF57 ZNF658B ZBTB42 ZIM3 ZNF669 ZNF345	3.07e-17	1412	59	28	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF771 KLF16 ZNF668 KLF8 ZNF845 ZNF526 ZNF676 ZNF773 ZNF142 ZNF219 WIZ KLF6 ZNF658 ZNF559 MAX ZNF611 ZNF620 ZNF398 ZFHX2 ZBTB8A KLF3 ZNF57 ZNF658B ZIM3 ZNF669 ZNF345	8.66e-15	1459	59	26	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF771 KLF16 ZNF668 KLF8 ZNF845 ZNF526 ZNF676 ZNF773 ZNF219 WIZ KLF6 ZNF658 MAX ZNF611 ZFHX2 ZBTB8A KLF3 ZNF658B ZIM3 ZNF345	1.80e-10	1244	59	20	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF771 KLF16 ZNF668 KLF8 ZNF845 ZNF526 ZNF676 ZNF773 ZNF219 WIZ KLF6 ZNF658 MAX ZNF611 ZFHX2 ZBTB8A KLF3 ZNF658B ZIM3 ZNF345	2.63e-10	1271	59	20	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	KLF16 ZNF668 KLF8 ZNF219 MAX ZBTB8A	3.57e-04	320	59	6	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	KLF16 ZNF668 KLF8 ZNF219 MAX ZBTB8A	3.94e-04	326	59	6	GO:0001217
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZNF771 ZNF668 ZNF845 KLF6 ZNF658 ZNF658B ZNF345	1.27e-03	560	59	7	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	ZNF771 ZNF668 ZNF845 KLF6 ZNF658 ZNF658B ZNF345	1.35e-03	566	59	7	GO:0001216
GeneOntologyMolecularFunction	GTPase activator activity	ARHGAP15 RASA4 RASGRP3 RASA4B SGSM3	1.39e-03	279	59	5	GO:0005096
GeneOntologyMolecularFunction	small GTPase binding	KNTC1 ANKFY1 RASGRP3 SGSM3 XPOT	2.56e-03	321	59	5	GO:0031267
GeneOntologyMolecularFunction	GTPase regulator activity	ARHGEF40 ARHGAP15 RASA4 RASGRP3 RASA4B SGSM3	3.75e-03	507	59	6	GO:0030695
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	ARHGEF40 ARHGAP15 RASA4 RASGRP3 RASA4B SGSM3	3.75e-03	507	59	6	GO:0060589
GeneOntologyMolecularFunction	GTPase binding	KNTC1 ANKFY1 RASGRP3 SGSM3 XPOT	4.18e-03	360	59	5	GO:0051020
Domain	Znf_C2H2-like	ZNF771 KLF16 ZNF668 KLF8 ZNF845 ZNF526 ZNF676 ZNF773 ZNF142 ZNF219 WIZ KLF6 ZNF658 ZNF559 FIZ1 ZBTB8B ZNF611 ZNF620 FBXO41 ZNF398 ZFHX2 ZBTB8A KLF3 ZNF57 ZNF598 ZBTB42 ZIM3 ZNF669 ZNF345	1.03e-24	796	58	29	IPR015880
Domain	Znf_C2H2	ZNF771 KLF16 ZNF668 KLF8 ZNF845 ZNF526 ZNF676 ZNF773 ZNF142 ZNF219 WIZ KLF6 ZNF658 ZNF559 FIZ1 ZBTB8B ZNF611 ZNF620 FBXO41 ZNF398 ZFHX2 ZBTB8A KLF3 ZNF57 ZNF598 ZBTB42 ZIM3 ZNF669 ZNF345	1.41e-24	805	58	29	IPR007087
Domain	ZnF_C2H2	ZNF771 KLF16 ZNF668 KLF8 ZNF845 ZNF526 ZNF676 ZNF773 ZNF142 ZNF219 WIZ KLF6 ZNF658 ZNF559 FIZ1 ZBTB8B ZNF611 ZNF620 FBXO41 ZNF398 ZFHX2 ZBTB8A KLF3 ZNF57 ZNF598 ZBTB42 ZIM3 ZNF669 ZNF345	1.57e-24	808	58	29	SM00355
Domain	ZINC_FINGER_C2H2_2	ZNF771 KLF16 ZNF668 KLF8 ZNF845 ZNF526 ZNF676 ZNF773 ZNF142 ZNF219 WIZ KLF6 ZNF658 ZNF559 FIZ1 ZBTB8B ZNF611 ZNF620 ZNF398 ZFHX2 ZBTB8A KLF3 ZNF57 ZNF598 ZBTB42 ZIM3 ZNF669 ZNF345	1.12e-23	775	58	28	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF771 KLF16 ZNF668 KLF8 ZNF845 ZNF526 ZNF676 ZNF773 ZNF142 ZNF219 WIZ KLF6 ZNF658 ZNF559 FIZ1 ZBTB8B ZNF611 ZNF620 ZNF398 ZFHX2 ZBTB8A KLF3 ZNF57 ZNF598 ZBTB42 ZIM3 ZNF669 ZNF345	1.20e-23	777	58	28	PS00028
Domain	-	ZNF771 KLF16 ZNF668 KLF8 ZNF845 ZNF526 ZNF676 ZNF773 ZNF142 ZNF219 KLF6 ZNF658 ZNF559 FIZ1 ZBTB8B ZNF611 ZNF620 ZNF398 ZFHX2 ZBTB8A KLF3 ZNF57 ZBTB42 ZIM3 ZNF669 ZNF345	1.74e-22	679	58	26	3.30.160.60
Domain	zf-C2H2	ZNF771 KLF16 ZNF668 KLF8 ZNF845 ZNF526 ZNF676 ZNF773 ZNF142 ZNF219 KLF6 ZNF658 ZNF559 FIZ1 ZBTB8B ZNF611 ZNF620 FBXO41 ZNF398 ZFHX2 ZBTB8A KLF3 ZNF57 ZIM3 ZNF669 ZNF345	2.92e-22	693	58	26	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF771 KLF16 ZNF668 KLF8 ZNF845 ZNF526 ZNF676 ZNF773 ZNF142 ZNF219 KLF6 ZNF658 ZNF559 FIZ1 ZBTB8B ZNF611 ZNF620 ZNF398 ZFHX2 ZBTB8A KLF3 ZNF57 ZBTB42 ZIM3 ZNF669 ZNF345	3.02e-22	694	58	26	IPR013087
Domain	zf-C2H2_6	ZNF771 ZNF668 ZNF845 ZNF526 ZNF676 ZNF773 ZNF658 ZNF611 ZNF620 ZIM3 ZNF669 ZNF345	1.85e-10	314	58	12	PF13912
Domain	KRAB	ZNF845 ZNF676 ZNF773 ZNF658 ZNF559 ZNF611 ZNF620 ZNF398 ZNF57 ZIM3 ZNF669	1.12e-08	358	58	11	PS50805
Domain	KRAB	ZNF845 ZNF676 ZNF773 ZNF658 ZNF559 ZNF611 ZNF620 ZNF398 ZNF57 ZIM3 ZNF669	1.53e-08	369	58	11	SM00349
Domain	KRAB	ZNF845 ZNF676 ZNF773 ZNF658 ZNF559 ZNF611 ZNF620 ZNF398 ZNF57 ZIM3 ZNF669	1.57e-08	370	58	11	IPR001909
Domain	KRAB	ZNF845 ZNF773 ZNF658 ZNF559 ZNF611 ZNF620 ZNF398 ZNF57 ZIM3 ZNF669	1.36e-07	358	58	10	PF01352
Domain	-	RASA4 RASA4B	2.84e-05	3	58	2	4.10.1130.10
Domain	BTK	RASA4 RASA4B	3.36e-04	9	58	2	SM00107
Domain	ZF_BTK	RASA4 RASA4B	3.36e-04	9	58	2	PS51113
Domain	Znf_Btk_motif	RASA4 RASA4B	3.36e-04	9	58	2	IPR001562
Domain	BTK	RASA4 RASA4B	3.36e-04	9	58	2	PF00779
Domain	BTB	ANKFY1 ZBTB8B ZBTB8A ZBTB42	7.32e-04	131	58	4	PF00651
Domain	RasGAP	RASA4 RASA4B	8.42e-04	14	58	2	SM00323
Domain	RasGAP_CS	RASA4 RASA4B	8.42e-04	14	58	2	IPR023152
Domain	RAS_GTPASE_ACTIV_2	RASA4 RASA4B	9.70e-04	15	58	2	PS50018
Domain	RasGAP	RASA4 RASA4B	9.70e-04	15	58	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	RASA4 RASA4B	9.70e-04	15	58	2	PS00509
Domain	-	RASA4 RASA4B	1.11e-03	16	58	2	1.10.506.10
Domain	F-box	FBXW8 FBXO41 KDM2A	1.18e-03	67	58	3	PF00646
Domain	RasGAP_dom	RASA4 RASA4B	1.40e-03	18	58	2	IPR001936
Domain	FBOX	FBXW8 FBXO41 KDM2A	1.46e-03	72	58	3	PS50181
Domain	BTB	ANKFY1 ZBTB8B ZBTB8A ZBTB42	1.54e-03	160	58	4	PS50097
Domain	F-box_dom	FBXW8 FBXO41 KDM2A	1.64e-03	75	58	3	IPR001810
Domain	BTB	ANKFY1 ZBTB8B ZBTB8A ZBTB42	2.36e-03	180	58	4	SM00225
Domain	Rho_GTPase_activation_prot	ARHGAP15 RASA4 RASA4B	2.59e-03	88	58	3	IPR008936
Domain	BTB/POZ_dom	ANKFY1 ZBTB8B ZBTB8A ZBTB42	2.61e-03	185	58	4	IPR000210
Domain	SKP1/BTB/POZ	ANKFY1 ZBTB8B ZBTB8A ZBTB42	2.81e-03	189	58	4	IPR011333
Domain	FYVE	ZFYVE28 ANKFY1	3.65e-03	29	58	2	PF01363
Domain	FYVE	ZFYVE28 ANKFY1	3.65e-03	29	58	2	SM00064
Domain	Znf_FYVE-rel	ZFYVE28 ANKFY1	4.99e-03	34	58	2	IPR017455
Domain	Znf_FYVE	ZFYVE28 ANKFY1	6.20e-03	38	58	2	IPR000306
Domain	ZF_FYVE	ZFYVE28 ANKFY1	6.85e-03	40	58	2	PS50178
Domain	F-box-like	FBXW8 FBXO41	8.25e-03	44	58	2	PF12937
Domain	Znf_FYVE_PHD	ZFYVE28 ANKFY1 KDM2A	1.07e-02	147	58	3	IPR011011
Domain	PH	ARHGEF40 ARHGAP15 RASA4 RASA4B	1.09e-02	278	58	4	SM00233
Domain	PH_DOMAIN	ARHGEF40 ARHGAP15 RASA4 RASA4B	1.10e-02	279	58	4	PS50003
Domain	PH_domain	ARHGEF40 ARHGAP15 RASA4 RASA4B	1.11e-02	280	58	4	IPR001849
Domain	FBOX	FBXW8 KDM2A	1.14e-02	52	58	2	SM00256
Domain	-	ZFYVE28 ANKFY1 KDM2A TRIM47 ZNF598	1.27e-02	449	58	5	3.30.40.10
Domain	Znf_RING/FYVE/PHD	ZFYVE28 ANKFY1 KDM2A TRIM47 ZNF598	1.38e-02	459	58	5	IPR013083
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF771 ZNF668 ZNF676 ZNF773 ATRIP ZNF658 ZNF559 MAX ZNF611 ZNF620 ZNF398 ZIM3 ZNF669	7.26e-05	1387	40	13	M734
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	KLF16 ZNF668 KLF8 ZNF773 ZNF219 ANKFY1 WIZ KLF6 MAX FIZ1 ZBTB8B ZNF398 ZBTB8A KLF3 ZNF598	4.21e-12	808	59	15	20412781
Pubmed	Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes.	KLF16 KLF8 KLF6 KLF3	3.66e-09	12	59	4	15937668
Pubmed	Mammalian SP/KLF transcription factors: bring in the family.	KLF16 KLF8 KLF6 KLF3	9.20e-08	25	59	4	15820306
Pubmed	CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.	RASA4 RASA4B	2.83e-06	2	59	2	11448776
Pubmed	An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.	RASA4 RASA4B	2.83e-06	2	59	2	16041389
Pubmed	Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS.	KLF16 KLF6	2.83e-06	2	59	2	33686288
Pubmed	M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP.	FBXW8 FBXO41 KDM2A	3.72e-06	18	59	3	15070733
Pubmed	A network of Krüppel-like Factors (Klfs). Klf8 is repressed by Klf3 and activated by Klf1 in vivo.	KLF8 KLF3	8.48e-06	3	59	2	18687676
Pubmed	CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.	RASA4 RASA4B	8.48e-06	3	59	2	25637021
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF845 ZNF611 ZNF620 ZNF57 ZNF669	1.44e-05	181	59	5	37372979
Pubmed	Deregulated expression of Kruppel-like factors in acute myeloid leukemia.	KLF6 KLF3	1.69e-05	4	59	2	21470678
Pubmed	Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.	RASA4 RASA4B	1.69e-05	4	59	2	21460216
Pubmed	The LIM protein FHL3 binds basic Krüppel-like factor/Krüppel-like factor 3 and its co-repressor C-terminal-binding protein 2.	KLF8 KLF3	1.69e-05	4	59	2	12556451
Pubmed	Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding.	RASA4 RASA4B	1.69e-05	4	59	2	16234249
Pubmed	Krüppel-like factors in hepatocellular carcinoma.	KLF8 KLF6	2.82e-05	5	59	2	25652467
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	KLF16 ZNF668 ZNF845 SRSF10 ZNF219 WIZ C16orf87 MAX FIZ1 KDM2A	5.86e-05	1294	59	10	30804502
Pubmed	Comparative genome mapping in the sequence-based era: early experience with human chromosome 7.	RASA4 RASA4B	7.87e-05	8	59	2	10810084
Pubmed	Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system.	ZNF219 ZBTB8A ZNF598 ZBTB42	9.12e-05	138	59	4	28786561
Pubmed	Generation of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencing.	KLF8 KLF3	1.01e-04	9	59	2	23716600
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	ZNF219 WIZ MAX FIZ1	1.13e-04	146	59	4	23892456
Pubmed	Systematic analysis and nomenclature of mammalian F-box proteins.	FBXW8 FBXO41 KDM2A	1.56e-04	61	59	3	15520277
Pubmed	ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex.	ZBTB8B ZBTB8A ZBTB42	1.71e-04	63	59	3	34351428
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	ZNF219 ANKFY1 KLF6 MAX ZFHX2 KLF3 TRIM47	1.93e-04	709	59	7	22988430
Pubmed	Klf5 regulates muscle differentiation by directly targeting muscle-specific genes in cooperation with MyoD in mice.	KLF16 KLF6	2.93e-04	15	59	2	27743478
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	ZNF771 KLF16 KLF6 MAX KLF3 ZNF345	3.18e-04	544	59	6	28473536
Pubmed	Partial transcriptome of the developing pituitary gland.	AMPH APC	3.34e-04	16	59	2	11161784
Pubmed	The Transcriptional Activator Krüppel-like Factor-6 Is Required for CNS Myelination.	KLF6 APC	3.34e-04	16	59	2	27213272
Pubmed	Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.	ZNF773 WIZ ZNF620	3.87e-04	83	59	3	20562864
Pubmed	SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.	SRSF10 ANKFY1 TTC17 POLA2 LRRFIP2	4.57e-04	378	59	5	34315543
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	KNTC1 WIZ KLF6 APC KDM2A	5.77e-04	398	59	5	35016035
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	KLF16 FBXW8 WIZ MAX KDM2A ZNF598 LRRFIP2	6.03e-04	857	59	7	25609649
Pubmed	Human transcription factor protein interaction networks.	ZNF771 KLF16 KLF8 WIZ KLF6 MAX ZNF611 KLF3 XPOT	6.41e-04	1429	59	9	35140242
Pubmed	Multimodal Hox5 activity generates motor neuron diversity.	KLF6 KLF3	1.12e-03	29	59	2	39289460
Pubmed	CRL4AMBRA1 is a master regulator of D-type cyclins.	FBXW8 KDM2A	1.19e-03	30	59	2	33854235
Pubmed	Novel protein interactions with endoglin and activin receptor-like kinase 1: potential role in vascular networks.	DLG5 RASA4 RASA4B	1.30e-03	126	59	3	24319055
Pubmed	Characterization of long cDNA clones from human adult spleen.	KDM2A SGSM3	1.44e-03	33	59	2	11214971
Pubmed	Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.	APC KDM2A	1.53e-03	34	59	2	30894540
Interaction	CABP5 interactions	ZNF559 ZNF620 ZNF398 ZBTB42 ZNF669	1.10e-07	40	59	5	int:CABP5
Interaction	MBTD1 interactions	KLF16 KLF8 KLF6 MAX KLF3	8.02e-07	59	59	5	int:MBTD1
Interaction	NOTCH2 interactions	ZNF771 ZNF668 ZNF526 ZNF142 ZNF219 FIZ1 ZNF611 ZNF398 ZNF598	3.60e-06	423	59	9	int:NOTCH2
Interaction	TRIM41 interactions	ZNF526 ZNF773 ZNF219 ZBTB8B ZNF398 ZBTB8A ZNF669	3.87e-06	223	59	7	int:TRIM41
Interaction	EPC1 interactions	KLF16 KLF8 KLF6 MAX KLF3	3.91e-06	81	59	5	int:EPC1
Interaction	LMO3 interactions	ZNF526 ZBTB8B ZNF620 ZBTB8A ZIM3 SHISA6	5.40e-06	152	59	6	int:LMO3
Interaction	KAT5 interactions	ZNF668 KLF8 ZNF526 KLF6 MAX ZBTB8A SHISA6 LRRFIP2	9.23e-06	358	59	8	int:KAT5
Interaction	ZNF250 interactions	ZNF668 ZBTB8B ZBTB8A ZNF57 ZNF345	3.37e-05	126	59	5	int:ZNF250
Interaction	WIZ interactions	KLF16 KLF8 WIZ MAX APC KLF3	4.40e-05	220	59	6	int:WIZ
Interaction	EPC2 interactions	KLF8 KLF6 MAX KLF3	4.42e-05	67	59	4	int:EPC2
Interaction	ZNF408 interactions	ZNF526 FBXW8 ZBTB8B APC ZBTB8A	6.59e-05	145	59	5	int:ZNF408
Interaction	VPS72 interactions	KLF16 KLF8 KLF6 MAX KLF3	6.81e-05	146	59	5	int:VPS72
Interaction	LTBP2 interactions	ZNF526 ZNF611 ZNF398 ZNF57	1.12e-04	85	59	4	int:LTBP2
Interaction	ING3 interactions	KLF16 KLF8 KLF6 MAX	1.40e-04	90	59	4	int:ING3
Interaction	PCGF6 interactions	KLF16 KLF8 ZNF526 MAX KLF3	1.43e-04	171	59	5	int:PCGF6
Interaction	CTBP1 interactions	KLF8 ZNF219 ANKFY1 WIZ APC KLF3 ZBTB42	1.77e-04	406	59	7	int:CTBP1
Interaction	SAP130 interactions	KLF16 KLF8 ZNF219 MAX KLF3	1.87e-04	181	59	5	int:SAP130
Interaction	EP400 interactions	KLF16 KLF8 KLF6 MAX KLF3	2.02e-04	184	59	5	int:EP400
Interaction	ZBTB14 interactions	KLF16 KLF8 ATRIP KLF3	2.11e-04	100	59	4	int:ZBTB14
Interaction	ZNF644 interactions	KLF16 KLF8 WIZ KLF6 KLF3	2.12e-04	186	59	5	int:ZNF644
Interaction	NFIA interactions	KLF16 KLF8 SRSF10 WIZ KLF3	2.23e-04	188	59	5	int:NFIA
Interaction	EHMT1 interactions	KLF16 KLF8 WIZ MAX KLF3	2.23e-04	188	59	5	int:EHMT1
Interaction	TAF5L interactions	KNTC1 KLF8 KLF6 KLF3	2.73e-04	107	59	4	int:TAF5L
Interaction	TRIM39 interactions	ZNF773 ZNF658 ZNF620 ZNF669	2.83e-04	108	59	4	int:TRIM39
Interaction	ARID4B interactions	KLF16 KLF8 ZNF219 MAX KLF3	2.90e-04	199	59	5	int:ARID4B
Interaction	PHF12 interactions	KLF16 KLF8 KLF6 KLF3	3.04e-04	110	59	4	int:PHF12
Interaction	EHMT2 interactions	KLF16 KLF8 WIZ KLF6 MAX KLF3	3.12e-04	315	59	6	int:EHMT2
Interaction	KLF8 interactions	ZNF771 KLF8 WIZ MAX ZNF611 SGSM3	3.94e-04	329	59	6	int:KLF8
Interaction	ZNF276 interactions	ZBTB8B APC ZBTB8A	3.99e-04	49	59	3	int:ZNF276
Interaction	NFRKB interactions	KLF16 KLF8 KLF3 XPOT	4.23e-04	120	59	4	int:NFRKB
Cytoband	1p35.1	ZBTB8B ZBTB8A	8.12e-04	32	60	2	1p35.1
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF845 ZNF526 ZNF773 FIZ1 ZNF611 ZIM3 ZNF345	9.10e-04	1192	60	7	chr19q13
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF771 KLF16 ZNF668 KLF8 ZNF845 ZNF526 ZNF676 ZNF773 ZNF142 ZNF219 WIZ KLF6 ZNF658 ZNF559 FIZ1 ZBTB8B ZNF611 ZNF620 ZNF398 ZFHX2 ZBTB8A KLF3 ZNF57 ZNF598 ZBTB42 ZIM3 ZNF669 ZNF345	2.92e-26	718	51	28	28
GeneFamily	Zinc fingers C2H2-type\|Kruppel like factors	KLF16 KLF8 KLF6 KLF3	1.67e-07	18	51	4	624
GeneFamily	Pleckstrin homology domain containing\|SH2 domain containing\|C2 and RasGAP domain containing	RASA4 RASA4B	3.46e-04	10	51	2	830
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	ANKFY1 ZBTB8B ZBTB8A ZBTB42	5.50e-04	134	51	4	861
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	ZFYVE28 ANKFY1	3.44e-03	31	51	2	81
Drug	estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A	ZNF771 AMPH MAX ZNF611 FBXO41 APC ZNF669	7.23e-07	199	58	7	1633_UP
Drug	Thiamphenicol [15318-45-3]; Up 200; 11.2uM; HL60; HT_HG-U133A	ZNF668 ZNF219 KLF6 FBXO41 APC ZFHX2	1.05e-05	196	58	6	1867_UP
Drug	Oxprenolol hydrochloride [6452-73-9]; Down 200; 13.2uM; MCF7; HT_HG-U133A	ZNF668 ZNF219 ANKFY1 MAX APC SGSM3	1.05e-05	196	58	6	3568_DN
Drug	Mephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A	ANKFY1 WIZ KLF6 MAX KLF3 KDM2A	1.08e-05	197	58	6	3425_DN
Drug	Nitrendipine [39562-70-4]; Down 200; 11uM; MCF7; HT_HG-U133A	DLG5 MAX APC KDM2A SGSM3 LRRFIP2	1.11e-05	198	58	6	6464_DN
Drug	Dibucaine [85-79-0]; Up 200; 11.6uM; HL60; HG-U133A	ZNF668 ARHGEF40 WIZ KLF6 MAX SGSM3	1.18e-05	200	58	6	1969_UP
Drug	fluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A	KLF6 MAX APC SGSM3 LRRFIP2	1.14e-04	187	58	5	1662_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A	ZNF668 DLG5 ZNF142 WIZ KDM2A	1.29e-04	192	58	5	2450_DN
Drug	Terazosin hydrochloride [63590-64-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A	ZNF611 APC ZFHX2 TTC17 ZNF669	1.32e-04	193	58	5	7187_UP
Drug	Etodolac [41340-25-4]; Down 200; 14uM; PC3; HT_HG-U133A	DLG5 ANKFY1 MAX KDM2A ZNF669	1.36e-04	194	58	5	2091_DN
Drug	Dosulepin hydrochloride [897-15-4]; Down 200; 12uM; MCF7; HT_HG-U133A	ZNF668 ANKFY1 WIZ APC SGSM3	1.36e-04	194	58	5	2864_DN
Drug	phentolamine; Down 200; 11.5uM; MCF7; HT_HG-U133A_EA	ANKFY1 MAX ZNF611 TRMT1 TTC17	1.39e-04	195	58	5	1138_DN
Drug	Sulindac [38194-50-2]; Up 200; 11.2uM; HL60; HT_HG-U133A	ANKFY1 KLF6 FBXO41 APC SGSM3	1.39e-04	195	58	5	1857_UP
Drug	Acetylsalicylsalicylic acid [530-75-6]; Down 200; 13.4uM; MCF7; HT_HG-U133A	ZNF771 DLG5 WIZ KLF6 SGSM3	1.39e-04	195	58	5	2223_DN
Drug	Tropine [120-29-6]; Up 200; 28.4uM; HL60; HT_HG-U133A	ZNF771 ZNF668 AMPH MAX ZFHX2	1.39e-04	195	58	5	6147_UP
Drug	Methazolamide [554-57-4]; Down 200; 17uM; HL60; HT_HG-U133A	ANKFY1 MAX KLF3 KDM2A SGSM3	1.42e-04	196	58	5	2733_DN
Drug	retinoic acid; Down 200; 1uM; MCF7; HG-U133A	ZNF668 ARHGEF40 RHBDF1 CEP112 FBXO41	1.46e-04	197	58	5	224_DN
Drug	3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; HL60; HT_HG-U133A	ZNF771 ZNF668 RHBDF1 ZFHX2 SGSM3	1.46e-04	197	58	5	2204_DN
Drug	Sisomicin sulfate [53179-09-2]; Up 200; 2.8uM; PC3; HT_HG-U133A	AMPH ARHGAP15 APC KLF3 SGSM3	1.46e-04	197	58	5	4014_UP
Drug	Tiaprofenic acid [33005-95-7]; Down 200; 15.4uM; HL60; HT_HG-U133A	ZNF668 ZNF219 FBXO41 KDM2A ZNF345	1.46e-04	197	58	5	2492_DN
Drug	Dizocilpine maleate [77086-22-7]; Down 200; 11.8uM; PC3; HT_HG-U133A	ZNF668 WIZ KLF6 ZFHX2 SGSM3	1.46e-04	197	58	5	5746_DN
Drug	Nicergoline; Down 200; 8.2uM; MCF7; HT_HG-U133A	ZNF668 MAX KDM2A TTC17 LRRFIP2	1.46e-04	197	58	5	6251_DN
Drug	Idazoxan hydrochloride [79944-56-2]; Down 200; 16.6uM; HL60; HT_HG-U133A	ARHGEF40 RHBDF1 FBXO41 KLF3 SGSM3	1.49e-04	198	58	5	3088_DN
Drug	beta- Belladonnine dichloroethylate [191355-47-2]; Down 200; 6uM; HL60; HT_HG-U133A	ZNF771 MAX ZFHX2 KDM2A ZNF345	1.49e-04	198	58	5	2164_DN
Drug	Brompheniramine maleate [980-71-2]; Up 200; 9.2uM; PC3; HT_HG-U133A	AMPH ZNF219 ZFHX2 KLF3 ZNF345	1.49e-04	198	58	5	4013_UP
Drug	Naringin hydrate [11032-30-7]; Down 200; 6.6uM; PC3; HT_HG-U133A	ANKFY1 WIZ CEP112 SGSM3 POLA2	1.49e-04	198	58	5	4605_DN
Drug	arachidonic acid sodium salt; Up 200; 10uM; MCF7; HG-U133A	ZNF771 ZNF219 WIZ KLF6 TRMT1	1.49e-04	198	58	5	443_UP
Drug	Sulfachloropyridazine [80-32-0]; Down 200; 14uM; HL60; HT_HG-U133A	ZNF771 ZNF668 ARHGEF40 RHBDF1 SGSM3	1.49e-04	198	58	5	2191_DN
Drug	clofibrate; Up 200; 100uM; MCF7; HG-U133A	ZNF771 ZNF219 WIZ KLF6 TRMT1	1.53e-04	199	58	5	444_UP
Drug	Testosterone propionate [57-85-2]; Up 200; 11.6uM; HL60; HT_HG-U133A	ZNF668 KLF6 FBXO41 SGSM3 ZNF669	1.53e-04	199	58	5	1295_UP
Drug	Sulfinpyrazone [57-96-5]; Down 200; 9.8uM; PC3; HT_HG-U133A	ZNF668 ANKFY1 MAX ZFHX2 KLF3	1.53e-04	199	58	5	5753_DN
Disease	Gastric cancer	KLF6 APC	1.99e-04	11	57	2	cv:C0024623
Disease	Neoplasm of stomach	KLF6 APC	1.99e-04	11	57	2	cv:C0038356
Disease	GASTRIC CANCER	KLF6 APC	1.99e-04	11	57	2	613659
Disease	Benign neoplasm of stomach	KLF6 APC	4.89e-04	17	57	2	C0153943
Disease	Carcinoma in situ of stomach	KLF6 APC	4.89e-04	17	57	2	C0154060
Disease	Neoplasm of uncertain or unknown behavior of stomach	KLF6 APC	4.89e-04	17	57	2	C0496905
Disease	Stomach Carcinoma	KLF6 APC	7.52e-04	21	57	2	C0699791
Disease	Intellectual Disability	KLF8 ZNF526 ZNF142 APC TRMT1	1.71e-03	447	57	5	C3714756
Disease	Mental Retardation, Psychosocial	ZNF526 APC TRMT1	2.49e-03	139	57	3	C0025363
Disease	Profound Mental Retardation	ZNF526 APC TRMT1	2.49e-03	139	57	3	C0020796
Disease	Mental deficiency	ZNF526 APC TRMT1	2.49e-03	139	57	3	C0917816
Disease	response to antihypertensive drug	CEP112 ZIM3	2.86e-03	41	57	2	EFO_0005405

Protein segments in the cluster

Peptide	Gene	Start	Entry
FSRKARLSFRHQLHD	C17orf114	56	A0A1B0GUV1
ALSARERLRSFHRTH	ARHGEF40	1126	Q8TER5
SFLSRLLSEKRHLHS	GJA10	431	Q969M2
SSFHDDHFLSRIREK	CEP112	241	Q8N8E3
DSARHHLEALQSSKR	AMPH	146	P49418
SPKLFHLRERHADAR	RASA4	481	O43374
SPKLFHLRERHADAR	RASA4B	481	C9J798
ATREKIRSRFHGSHD	ZFYVE28	711	Q9HCC9
DRHISAHKFVLAARS	ANKFY1	76	Q9P2R3
FARSDELTRHFRKHT	KLF3	301	P57682
DRSFSRSDHLALHRK	KLF3	326	P57682
KKFARSDELARHHRT	KLF16	166	Q9BXK1
LERKRRDHIKDSFHS	MAX	31	P61244
RDHIKDSFHSLRDSV	MAX	36	P61244
ADLDSFTTHRRHRGL	FBXW8	541	Q8N3Y1
SAAARRSFFRRKHKH	DLG5	1681	Q8TDM6
ARSDELTRHFRKHTG	KLF8	316	O95600
SRLLHKHRFAEAESF	KNTC1	401	P50748
LEDSERARYSHRSSH	LRRFIP2	76	Q9Y608
SDHHSASRDERFKRR	KDM2A	746	Q9Y2K7
LENRKRSRSNSHSDH	C16orf87	81	Q6PH81
HKRFRSLSSLRAHLE	FBXO41	16	Q8TF61
SDLRRHFARHTALKP	FIZ1	36	Q96SL8
AAARDVSSDHKVHRL	ATRIP	76	Q8WXE1
EHHLRRSRRKSKFSD	SPATA6L	236	Q8N4H0
RSALLHADFRVSLSH	TRMT1	466	Q9NXH9
RLDSHFAGLFTHRLK	TRIM47	596	Q96LD4
LAEHLTFLEHKSFRR	RASGRP3	156	Q8IV61
HSFIRSAREREKHSA	RHBDF1	486	Q96CC6
FRLHHSASDTSDKNR	ARHGAP15	236	Q53QZ3
HRRRAKALLDFERHD	SGSM3	481	Q96HU1
SQTAAKRHAFASRRH	SHISA6	461	Q6ZSJ9
RAGLSSHARAHLRDF	WIZ	781	O95785
FENRKGLSSHARSHL	WIZ	1236	O95785
FENRKALASHARAHL	WIZ	1406	O95785
EHEFLSKRLSKARHS	POLA2	66	Q14181
RPAKRHDIARSHSES	APC	2521	P25054
TFSRKSSLTRHRRLH	ZNF845	391	Q96IR2
FSSKSRLQSHLRRHA	ZIM3	176	Q96PE6
AFSRSSSLTRHKRIH	ZNF676	541	Q8N7Q3
AFARRSTLAKHARTH	ZNF771	71	Q7L3S4
GKRFSRLDHLSSHFR	ZBTB8A	316	Q96BR9
SLRKHERTHRSSEAA	ZNF668	406	Q96K58
ASHLRSSAHRRKAAP	ZFHX2	2511	Q9C0A1
SRSHSDNDRFKHRNR	SRSF10	156	O75494
FADQARLTSHRRAHA	ZNF398	436	Q8TD17
SKRRHFTDTSARHHE	ZNF620	146	Q6ZNG0
RALHFSSRHNKDIAL	TTC17	251	Q96AE7
KTFADNSALRAHHRI	ZNF658	861	Q5TYW1
FSKTSHLRAHLRTRS	ZNF658	891	Q5TYW1
RSSKSREAFHAGKRH	ZNF773	176	Q6PK81
LHLSAHFRERDSTRA	ZBTB42	311	B2RXF5
DLKAHRTACHSRSRA	ZNF598	261	Q86UK7
AFLDHRGLRHSSAKV	XPOT	526	O43592
FASFTRHVRTHTKDR	ZNF57	236	Q68EA5
FASASRLSRHRRAVH	ZNF526	451	Q8TF50
KTFSRRSSLHCHRRL	ZNF611	601	Q8N823
TRFLLRTHLRKHSEA	ZNF142	1576	P52746
KSFSFESALIRHHRI	ZNF345	181	Q14585
SSFLIRHLRSHSAER	ZNF559	421	Q9BR84
KFRTSAERERHLHIL	ZNF219	171	Q9P2Y4
DQAFSRLSSLHLHER	ZNF669	396	Q96BR6
KTFADNSALRAHHRI	ZNF658B	621	Q4V348
FSKTSHLRAHLRTRS	ZNF658B	651	Q4V348
KRFTRQEHLRSHALS	ZBTB8B	376	Q8NAP8
FARSDELTRHFRKHT	KLF6	241	Q99612