Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK11 DOCK10 GCGR PREX2 DENND3 TIAM2 DOCK7 VAV3 SOS1

7.71e-062311159GO:0005085
GeneOntologyMolecularFunctionxylose binding

SLC2A14 SLC2A3

3.29e-0521152GO:0033222
GeneOntologyMolecularFunctionephrin receptor binding

PTPN1 EFNA2 EFNA4 EFNA5

3.31e-05321154GO:0046875
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DOCK11 ADGRB3 DOCK10 GCGR PREX2 DENND3 TIAM2 DOCK7 VAV3 RASAL1 SOS1

1.67e-0450711511GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

DOCK11 ADGRB3 DOCK10 GCGR PREX2 DENND3 TIAM2 DOCK7 VAV3 RASAL1 SOS1

1.67e-0450711511GO:0030695
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC1 ATP13A1 ABCA5 ABCD1

1.81e-04491154GO:0140359
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCC1 ATP13A1 ABCA5 ABCD1 ATP6V0A2

4.21e-041091155GO:0042626
GeneOntologyMolecularFunctiongalactose transmembrane transporter activity

SLC2A14 SLC2A3

4.86e-0461152GO:0005354
GeneOntologyMolecularFunctionATP-dependent activity

ABCC1 MYO1C ATP13A1 TWNK MSH2 DNAH7 MDN1 ATP11B ABCA5 ABCD1 ATP6V0A2

8.39e-0461411511GO:0140657
GeneOntologyMolecularFunctiondehydroascorbic acid transmembrane transporter activity

SLC2A14 SLC2A3

9.00e-0481152GO:0033300
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCC1 ATP13A1 TWNK MSH2 DNAH7 MDN1 ATP11B ABCA5 ABCD1

1.03e-034411159GO:0016887
GeneOntologyMolecularFunctionATPase-coupled lipid transmembrane transporter activity

ABCC1 ABCD1

1.15e-0391152GO:0034040
GeneOntologyMolecularFunctiongalactoside binding

SLC2A14 SLC2A3

1.15e-0391152GO:0016936
GeneOntologyMolecularFunctionvitamin transmembrane transporter activity

ABCC1 SLC2A14 SLC2A3

1.16e-03361153GO:0090482
GeneOntologyCellularComponentPTW/PP1 phosphatase complex

PPP1CA PPP1CB PPP1CC

5.73e-0671163GO:0072357
GeneOntologyCellularComponentprotein phosphatase type 1 complex

PPP1CA PPP1CB PPP1CC

1.51e-04191163GO:0000164
DomainSTPPase_N

PPP1CA PPP1CB PPP1CC

2.21e-0731143IPR031675
DomainSTPPase_N

PPP1CA PPP1CB PPP1CC

2.21e-0731143PF16891
DomainDUF3398

DOCK11 DOCK10 DOCK7

4.37e-0661143PF11878
DomainDOCK_C/D_N

DOCK11 DOCK10 DOCK7

4.37e-0661143IPR021816
DomainEphrin

EFNA2 EFNA4 EFNA5

1.21e-0581143PF00812
DomainEphrin_RBD

EFNA2 EFNA4 EFNA5

1.21e-0581143IPR001799
DomainEphrin

EFNA2 EFNA4 EFNA5

1.21e-0581143PD002533
DomainEphrin

EFNA2 EFNA4 EFNA5

1.21e-0581143IPR031328
DomainEPHRIN_RBD_1

EFNA2 EFNA4 EFNA5

1.21e-0581143PS01299
DomainEphrin_CS

EFNA2 EFNA4 EFNA5

1.21e-0581143IPR019765
DomainEPHRIN_RBD_2

EFNA2 EFNA4 EFNA5

1.21e-0581143PS51551
DomainDHR-1_domain

DOCK11 DOCK10 DOCK7

3.53e-05111143IPR027007
DomainDHR_2

DOCK11 DOCK10 DOCK7

3.53e-05111143PS51651
DomainDHR_1

DOCK11 DOCK10 DOCK7

3.53e-05111143PS51650
DomainDHR-2

DOCK11 DOCK10 DOCK7

3.53e-05111143PF06920
DomainDOCK

DOCK11 DOCK10 DOCK7

3.53e-05111143IPR026791
DomainDOCK_C

DOCK11 DOCK10 DOCK7

3.53e-05111143IPR010703
DomainDOCK-C2

DOCK11 DOCK10 DOCK7

3.53e-05111143PF14429
DomainDHR-2

DOCK11 DOCK10 DOCK7

3.53e-05111143IPR027357
DomainGlc_transpt_3

SLC2A14 SLC2A3

3.69e-0521142IPR002945
DomainHECW_N

HECW1 HECW2

3.69e-0521142IPR032348
DomainHECW_N

HECW1 HECW2

3.69e-0521142PF16562
DomainMAGEA3/MAGEA6

MAGEA3 MAGEA6

3.69e-0521142IPR030097
DomainPP2Ac

PPP1CA PPP1CB PPP1CC

6.06e-05131143SM00156
DomainSer/Thr-sp_prot-phosphatase

PPP1CA PPP1CB PPP1CC

6.06e-05131143IPR006186
DomainSER_THR_PHOSPHATASE

PPP1CA PPP1CB PPP1CC

6.06e-05131143PS00125
Domain-

EFNA2 EFNA4 EFNA5

7.68e-051411432.60.40.420
DomainGDS_CDC24_CS

PREX2 TIAM2 VAV3 SOS1

9.18e-05391144IPR001331
DomainMAGE_N

MAGEA3 MAGEA6 MAGEA12

2.34e-04201143SM01392
DomainMAGE_N

MAGEA3 MAGEA6 MAGEA12

3.13e-04221143PF12440
DomainCupredoxin

EFNA2 EFNA4 EFNA5

3.13e-04221143IPR008972
DomainMAGE_N

MAGEA3 MAGEA6 MAGEA12

3.13e-04221143IPR021072
DomainBPI/LBP

BPI BPIFB2

3.65e-0451142IPR030675
DomainPH

DOCK11 DOCK10 PREX2 TIAM2 VAV3 RASAL1 SOS1

5.15e-042291147PF00169
DomainHECT

HECW1 HECTD2 HECW2

5.82e-04271143PF00632
DomainHECTc

HECW1 HECTD2 HECW2

5.82e-04271143SM00119
DomainHECT_dom

HECW1 HECTD2 HECW2

5.82e-04271143IPR000569
DomainHECT

HECW1 HECTD2 HECW2

5.82e-04271143PS50237
DomainDH_1

PREX2 TIAM2 VAV3 SOS1

5.94e-04631144PS00741
DomainMetallophos

PPP1CA PPP1CB PPP1CC

6.49e-04281143PF00149
DomainCalcineurin-like_PHP_ApaH

PPP1CA PPP1CB PPP1CC

6.49e-04281143IPR004843
DomainRhoGEF

PREX2 TIAM2 VAV3 SOS1

7.94e-04681144SM00325
DomainMetallo-depent_PP-like

PPP1CA PPP1CB PPP1CC

7.97e-04301143IPR029052
Domain-

PPP1CA PPP1CB PPP1CC

7.97e-043011433.60.21.10
DomainRhoGEF

PREX2 TIAM2 VAV3 SOS1

8.85e-04701144PF00621
DomainDH_2

PREX2 TIAM2 VAV3 SOS1

8.85e-04701144PS50010
Domain-

PREX2 TIAM2 VAV3 SOS1

9.34e-047111441.20.900.10
DomainDH-domain

PREX2 TIAM2 VAV3 SOS1

9.34e-04711144IPR000219
DomainMAGE

MAGEA3 MAGEA6 MAGEA12

1.15e-03341143SM01373
DomainBPI2

BPI BPIFB2

1.29e-0391142SM00329
DomainLBP_BPI_CETP

BPI BPIFB2

1.29e-0391142PS00400
DomainMAGE

MAGEA3 MAGEA6 MAGEA12

1.37e-03361143PS50838
DomainMHD_dom

MAGEA3 MAGEA6 MAGEA12

1.37e-03361143IPR002190
DomainMAGE

MAGEA3 MAGEA6 MAGEA12

1.37e-03361143PF01454
DomainPH

DOCK11 DOCK10 PREX2 TIAM2 VAV3 RASAL1 SOS1

1.59e-032781147SM00233
DomainLRR_5

LHCGR PODN

1.61e-03101142PF13306
DomainLRR_5

LHCGR PODN

1.61e-03101142IPR026906
DomainLBP_BPI_CETP_C

BPI BPIFB2

1.61e-03101142PF02886
DomainPH_DOMAIN

DOCK11 DOCK10 PREX2 TIAM2 VAV3 RASAL1 SOS1

1.63e-032791147PS50003
DomainPH_domain

DOCK11 DOCK10 PREX2 TIAM2 VAV3 RASAL1 SOS1

1.66e-032801147IPR001849
DomainAAA

ABCC1 DNAH7 MDN1 ABCA5 ABCD1

1.90e-031441145SM00382
DomainAAA+_ATPase

ABCC1 DNAH7 MDN1 ABCA5 ABCD1

1.90e-031441145IPR003593
DomainABC_transporter_CS

ABCC1 ABCA5 ABCD1

2.14e-03421143IPR017871
DomainLipid-bd_serum_glycop_C

BPI BPIFB2

2.34e-03121142IPR001124
DomainLBP_BPI_CETP

BPI BPIFB2

2.76e-03131142PF01273
DomainBPI/LBP/Plunc

BPI BPIFB2

2.76e-03131142IPR032942
DomainBactericidal_perm-incr_a/b_dom

BPI BPIFB2

2.76e-03131142IPR017943
DomainLipid-bd_serum_glycop_N

BPI BPIFB2

2.76e-03131142IPR017942
DomainABC_tran

ABCC1 ABCA5 ABCD1

3.14e-03481143PF00005
DomainABC_TRANSPORTER_2

ABCC1 ABCA5 ABCD1

3.14e-03481143PS50893
DomainSugar/inositol_transpt

SLC2A14 SLC2A3

3.20e-03141142IPR003663
DomainABC_TRANSPORTER_1

ABCC1 ABCA5 ABCD1

3.33e-03491143PS00211
DomainABC_transporter-like

ABCC1 ABCA5 ABCD1

3.52e-03501143IPR003439
DomainSUGAR_TRANSPORT_2

SLC2A14 SLC2A3

4.73e-03171142PS00217
PathwayREACTOME_RAC1_GTPASE_CYCLE

DOCK11 DOCK10 PREX2 TIAM2 DOCK7 VAV3 FMNL1 SOS1

1.22e-05175878MM15599
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_MRAS_SHOC2_PP1_HOLOPHOSPHATASE

PPP1CA PPP1CB PPP1CC

1.24e-058873M47933
PathwayREACTOME_TRIGLYCERIDE_CATABOLISM

PPP1CA PPP1CB PPP1CC PRKACA

1.31e-0524874M10064
PathwayREACTOME_RAC1_GTPASE_CYCLE

DOCK11 DOCK10 PREX2 TIAM2 DOCK7 VAV3 FMNL1 SOS1

1.75e-05184878M41809
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

SLC4A7 DOCK11 DOCK10 PREX2 TIAM2 PPP1CB PPP1CC TXNL1 DOCK7 VAV3 NUDC FMNL1 LRRC41 SOS1

4.01e-056498714MM15690
PathwayKEGG_MEDICUS_REFERENCE_CENPE_INTERACTION_WITH_NDC80_COMPLEX

PPP1CA PPP1CB PPP1CC

4.80e-0512873M47887
PathwayKEGG_MEDICUS_REFERENCE_DEPHOSPHORYLATION_OF_KINETOCHORE

PPP1CA PPP1CB PPP1CC

4.80e-0512873M47891
PathwayREACTOME_EPH_EPHRIN_MEDIATED_REPULSION_OF_CELLS

EFNA2 EFNA4 EFNA5 VAV3

5.45e-0534874MM15025
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ABCC1 SLC4A7 ATP13A1 SLC2A14 PSMD3 SLC2A3 ANO8 SLC9A4 ATP11B CLCNKB ABCA5 PRKACA ABCD1 ATP6V0A2

6.75e-056818714MM14985
PathwayREACTOME_RHO_GTPASE_CYCLE

SLC4A7 DOCK11 DOCK10 PREX2 TIAM2 TXNL1 DOCK7 VAV3 NUDC FMNL1 SOS1

7.83e-054398711MM15595
PathwayPID_RAC1_REG_PATHWAY

PREX2 TIAM2 VAV3 SOS1

8.51e-0538874M241
PathwayREACTOME_TRIGLYCERIDE_METABOLISM

PPP1CA PPP1CB PPP1CC PRKACA

8.51e-0538874M27856
PathwayREACTOME_RHO_GTPASE_CYCLE

SLC4A7 DOCK11 DOCK10 PREX2 TIAM2 TXNL1 DOCK7 VAV3 NUDC FMNL1 SOS1

9.76e-054508711M27078
PathwayWP_COMMON_PATHWAYS_UNDERLYING_DRUG_ADDICTION

PPP1CA PPP1CB PPP1CC PRKACA

1.15e-0441874M39655
PathwayREACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_RSV_GENOME_REPLICATION_TRANSCRIPTION_AND_TRANSLATION

PPP1CA PPP1CB PPP1CC

1.20e-0416873M48235
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

SLC4A7 DOCK11 DOCK10 PREX2 TIAM2 PPP1CB PPP1CC TXNL1 DOCK7 VAV3 NUDC FMNL1 LRRC41 SOS1

1.22e-047208714M41838
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ABCC1 SLC4A7 ATP13A1 SLC2A14 PSMD3 SLC2A3 ANO8 SLC9A4 ATP11B CLCNKB ABCA5 PRKACA ABCD1 ATP6V0A2

1.54e-047368714M27287
PathwayREACTOME_EPHA_MEDIATED_GROWTH_CONE_COLLAPSE

EFNA2 EFNA4 EFNA5

1.73e-0418873MM15023
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

PPP1CA PPP1CB PPP1CC TGFBR3

1.97e-0447874M646
PathwayKEGG_INSULIN_SIGNALING_PATHWAY

PPP1CA PPP1CB PPP1CC PTPN1 PRKACA SOS1

2.00e-04137876M18155
PathwayWP_NEUROINFLAMMATION_AND_GLUTAMATERGIC_SIGNALING

SLC2A3 PPP1CA PPP1CB PPP1CC TGFBR3 PRKACA

2.25e-04140876M42572
PathwayREACTOME_EPH_EPHRIN_MEDIATED_REPULSION_OF_CELLS

EFNA2 EFNA4 EFNA5 VAV3

2.71e-0451874M27311
PathwayREACTOME_CDC42_GTPASE_CYCLE

DOCK11 DOCK10 PREX2 DOCK7 VAV3

2.84e-0494875MM15598
PathwayREACTOME_CDC42_GTPASE_CYCLE

DOCK11 DOCK10 PREX2 DOCK7 VAV3 FMNL1

3.89e-04155876M41808
PathwayREACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING

PPP1CA PPP1CB PPP1CC

5.33e-0426873M628
PathwayREACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION

GCGR PRKACA

5.56e-046872MM14628
PathwayKEGG_OOCYTE_MEIOSIS

PPP1CA PPP1CB PPP1CC PRKACA PTTG2

6.63e-04113875M16817
PathwayREACTOME_EPH_EPHRIN_SIGNALING

EFNA2 EFNA4 EFNA5 VAV3

6.88e-0465874MM14911
PathwayREACTOME_EPHA_MEDIATED_GROWTH_CONE_COLLAPSE

EFNA2 EFNA4 EFNA5

7.39e-0429873M27309
PathwayPID_CDC42_REG_PATHWAY

DOCK11 DOCK10 VAV3

8.17e-0430873M83
PathwayWP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY

SLC2A14 SLC2A3 EFNA2 EFNA4 EFNA5 PIK3C2B PPP2R3C SOS1

8.98e-04326878MM15917
PathwayKEGG_LONG_TERM_POTENTIATION

PPP1CA PPP1CB PPP1CC PRKACA

9.10e-0470874M3115
PathwayREACTOME_SIGNALING_BY_MRAS_COMPLEX_MUTANTS

PPP1CB PPP1CC

1.03e-038872M38999
Pubmed

A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent inhibition of GSK-3beta.

PPP1CA PPP1CB PPP1CC PRKACA

4.08e-097116412147701
Pubmed

1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription.

PPP1CA PPP1CB PPP1CC

3.62e-083116325073485
Pubmed

Chromosomal localization of human, rat, and mouse protein phosphatase type 1 beta catalytic subunit genes (PPP1CB) by fluorescence in situ hybridization.

PPP1CA PPP1CB PPP1CC

3.62e-08311637857673
Pubmed

Protein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clock.

PPP1CA PPP1CB PPP1CC

3.62e-083116321712997
Pubmed

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts.

PPP1CA PPP1CB PPP1CC PRKACA

5.70e-0812116410830164
Pubmed

Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein.

PPP1CA PPP1CB PPP1CC

1.44e-074116316131488
Pubmed

Nuclear protein phosphatase-1 regulates HIV-1 transcription.

PPP1CA PPP1CB PPP1CC

1.44e-074116312788939
Pubmed

Protein phosphatase 1 inhibits p53 signaling by dephosphorylating and stabilizing Mdmx.

PPP1CA PPP1CB PPP1CC

1.44e-074116323277204
Pubmed

Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1.

PPP1CA PPP1CB PPP1CC

1.44e-074116310194355
Pubmed

Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1.

PPP1CA PPP1CB PPP1CC

1.44e-074116322768081
Pubmed

Glucose-dependent regulation of AMP-activated protein kinase in MIN6 beta cells is not affected by the protein kinase A pathway.

PPP1CA PPP1CB PRKACA

1.44e-074116323116618
Pubmed

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer.

MSH2 LHCGR SOS1

1.44e-07411638252616
Pubmed

Binding of the concave surface of the Sds22 superhelix to the alpha 4/alpha 5/alpha 6-triangle of protein phosphatase-1.

PPP1CA PPP1CB PPP1CC

1.44e-074116312226088
Pubmed

N-CoR controls differentiation of neural stem cells into astrocytes.

PPP1CA PPP1CB PPP1CC

1.44e-074116312410313
Pubmed

Distinct roles for the α , β and γ1 isoforms of protein phosphatase 1 in the outside-in αIIbβ3 integrin signalling-dependent functions.

PPP1CA PPP1CB PPP1CC

3.60e-075116323197154
Pubmed

Structural plasticity of eph receptor A4 facilitates cross-class ephrin signaling.

EFNA2 EFNA4 EFNA5

3.60e-075116319836338
Pubmed

Refined chromosomal localization of the mismatch repair and hereditary nonpolyposis colorectal cancer genes hMSH2 and hMSH6.

MSH2 LHCGR SOS1

3.60e-07511639823302
Pubmed

Association of the type 1 protein phosphatase PP1 with the A-kinase anchoring protein AKAP220.

PPP1CA PPP1CB PPP1CC

3.60e-075116310209101
Pubmed

The human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activity.

PPP1CA PPP1CB PPP1CC

3.60e-075116312016208
Pubmed

Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle.

PPP1CA PPP1CB PPP1CC

3.60e-075116311551964
Pubmed

Cloning and analysis of MAGE-1-related genes.

MAGEA3 MAGEA6 MAGEA12

3.60e-07511638037761
Pubmed

The heterotrimeric G protein Gβ1 interacts with the catalytic subunit of protein phosphatase 1 and modulates G protein-coupled receptor signaling in platelets.

PPP1CA PPP1CB PPP1CC

3.60e-075116328615442
Pubmed

A PP1-PP2A phosphatase relay controls mitotic progression.

PPP1CA PPP1CB PPP1CC

3.60e-075116325487150
Pubmed

SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1.

PPP1CA PPP1CB PPP1CC

3.60e-075116320424263
Pubmed

The interaction of PP1 with BRCA1 and analysis of their expression in breast tumors.

PPP1CA PPP1CB PPP1CC

3.60e-075116317511879
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

SLC4A7 ANK2 ATP13A1 TWNK HEATR1 LACTB PPP1CC TXNL1 PTPN1 MDN1 CDC123 CCDC138 PRKACA TMEM131L ELP2 HADHB NUDC ATP6V0A2 LRRC41

4.85e-0714871161933957083
Pubmed

SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1.

PPP1CA PPP1CB PPP1CC

7.18e-076116314640981
Pubmed

Crystal structure of an ephrin ectodomain.

EFNA2 EFNA4 EFNA5

7.18e-076116311703926
Pubmed

Dissociation of SHP-1 from spinophilin during platelet activation exposes an inhibitory binding site for protein phosphatase-1 (PP1).

PPP1CA PPP1CB PPP1CC

7.18e-076116325785436
Pubmed

Inhibitory member of the apoptosis-stimulating proteins of the p53 family (iASPP) interacts with protein phosphatase 1 via a noncanonical binding motif.

PPP1CA PPP1CB PPP1CC

7.18e-076116321998301
Pubmed

Protein phosphatase 1 regulates the phosphorylation state of the polarity scaffold Par-3.

PPP1CA PPP1CB PPP1CC

7.18e-076116318641122
Pubmed

Ephrin-A binding and EphA receptor expression delineate the matrix compartment of the striatum.

EFNA2 EFNA4 EFNA5

1.25e-067116310366629
Pubmed

Molecular development of sensory maps: representing sights and smells in the brain.

EFNA2 EFNA4 EFNA5

1.25e-06711639988220
Pubmed

Distinct and overlapping expression patterns of ligands for Eph-related receptor tyrosine kinases during mouse embryogenesis.

EFNA2 EFNA4 EFNA5

1.25e-06711638903354
Pubmed

Inhibitor-2 prevents protein phosphatase 1-induced cardiac hypertrophy and mortality.

PPP1CA PPP1CB PPP1CC

1.25e-067116318689497
Pubmed

SARP, a new alternatively spliced protein phosphatase 1 and DNA interacting protein.

PPP1CA PPP1CB PPP1CC

1.25e-067116317123353
Pubmed

Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development.

MSH2 LHCGR SOS1

1.25e-06711638575305
Pubmed

Expression of melanoma-associated antigens in oral squamous cell carcinoma.

MAGEA3 MAGEA6 MAGEA12

1.25e-067116318197853
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

SLC4A7 ANK2 HECW1 ATP13A1 ADGRB3 PSMD3 ANO8 PPP1CA PPP1CB PPP1CC TXNL1 PTPN1 DOCK7 HADHB NUDC RASAL1

1.27e-0611391161636417873
Pubmed

Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation.

PPP1CA PPP1CB PPP1CC

2.00e-068116316262633
Pubmed

MAGE cancer-testis antigens protect the mammalian germline under environmental stress.

MAGEA3 MAGEA6 MAGEA12

2.00e-068116331149633
Pubmed

Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping.

EFNA2 EFNA4 EFNA5

2.00e-068116310774725
Pubmed

The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1.

PPP1CA PPP1CB PPP1CC

2.00e-068116321930935
Pubmed

A protein phosphatase from human T cells augments tat transactivation of the human immunodeficiency virus type 1 long-terminal repeat.

PPP1CA PPP1CB PPP1CC

2.00e-068116312036313
Pubmed

The Magea gene cluster regulates male germ cell apoptosis without affecting the fertility in mice.

MAGEA3 MAGEA6 MAGEA12

2.00e-068116327226137
Pubmed

RRP1B targets PP1 to mammalian cell nucleoli and is associated with Pre-60S ribosomal subunits.

PPP1CA PPP1CB PPP1CC

2.99e-069116320926688
Pubmed

Topographic guidance labels in a sensory projection to the forebrain.

EFNA2 EFNA4 EFNA5

2.99e-06911639883724
Pubmed

Consensus PP1 binding motifs regulate transcriptional corepression and alternative RNA splicing activities of the steroid receptor coregulators, p54nrb and PSF.

PPP1CA PPP1CB PPP1CC

2.99e-069116321566083
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ATP13A1 POMGNT1 TWNK GRID1 TIAM2 ANO8 BMP4 EFNA2 PWWP2B MDN1 PIK3C2B USP40 ABCD1 PPP2R3C RASAL1

4.25e-0611051161535748872
Pubmed

Roles for ephrins in positionally selective synaptogenesis between motor neurons and muscle fibers.

EFNA2 EFNA4 EFNA5

4.26e-0610116310719886
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

UTP6 MYO1C RTCB TUT7 PSMD3 MSH2 HEATR1 LACTB PPP1CA PPP1CB PPP1CC PTPN1 ANGEL2 DOCK7 HADHB NUDC

4.49e-0612571161636526897
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ANK2 MYO1C RTCB SLC2A14 PSMD3 SLC2A3 LACTB PPP1CA PPP1CB PPP1CC P2RX3 HECW2 PRKACA DOCK7 HADHB RASAL1 DNPEP

5.48e-0614311161737142655
Pubmed

Selective inhibition of spinal cord neurite outgrowth and cell survival by the Eph family ligand ephrin-A5.

EFNA2 EFNA4 EFNA5

5.85e-0611116310559410
Pubmed

Expression of ephrin-A ligands and EphA receptors in the developing mouse tooth and its supporting tissues.

EFNA2 EFNA4 EFNA5

5.85e-0611116315517401
Pubmed

Ephrin/ephrin receptor expression during early stages of mouse inner ear development.

EFNA2 EFNA4 EFNA5

7.78e-0612116321465626
Pubmed

EphrinA-EphA receptor interactions in mouse spinal neurulation: implications for neural fold fusion.

EFNA2 EFNA4 EFNA5

7.78e-0612116319247962
Pubmed

ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2.

RTCB PPP1CA PPP1CB PPP1CC

7.94e-0638116430629181
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

SLC4A7 MYO1C TUT7 TWNK HEATR1 LACTB TXNL1 PTPN1 BNIP3L MDN1 ANGEL2 CCDC138 PRKACA C8orf82 CLN6 HADHB NUDC

9.78e-0614961161732877691
Pubmed

Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions.

PPP1CA PPP1CB PPP1CC PRKACA

9.79e-0640116423555304
Pubmed

Eph-ephrin A system regulates murine blastocyst attachment and spreading.

EFNA2 EFNA4 EFNA5

1.01e-0513116317039519
Pubmed

EphA family gene expression in the developing mouse neocortex: regional patterns reveal intrinsic programs and extrinsic influence.

EFNA2 EFNA4 EFNA5

1.01e-0513116312528186
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ABCC1 MYO1C PSMD3 MSH2 PHF8 PPP1CA PPP1CB PPP1CC PTPN1 CCDC138 PRKACA ELP2 HADHB NUDC

1.10e-0510491161427880917
Pubmed

Reprogramming- and pluripotency-associated membrane proteins in mouse stem cells revealed by label-free quantitative proteomics.

SLC2A14 SLC2A3

1.10e-052116223615220
Pubmed

Ephrin-A2 and -A5 influence patterning of normal and novel retinal projections to the thalamus: conserved mapping mechanisms in visual and auditory thalamic targets.

EFNA2 EFNA5

1.10e-052116215924339
Pubmed

A role for ephrin-As in maintaining topographic organization in register across interconnected central visual pathways.

EFNA2 EFNA5

1.10e-052116220384808
Pubmed

The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases.

PPP1CB PPP1CC

1.10e-05211622544298
Pubmed

miR-1273g silences MAGEA3/6 to inhibit human colorectal cancer cell growth via activation of AMPK signaling.

MAGEA3 MAGEA6

1.10e-052116230056111
Pubmed

Modulation of dendritic cell trafficking to and from the airways.

ABCC1 CCR8

1.10e-052116216517726
Pubmed

Online LI-rTMS during a Visual Learning Task: Differential Impacts on Visual Circuit and Behavioral Plasticity in Adult Ephrin-A2A5-/- Mice.

EFNA2 EFNA5

1.10e-052116229464193
Pubmed

Copy-Number Variation of the Glucose Transporter Gene SLC2A3 and Congenital Heart Defects in the 22q11.2 Deletion Syndrome.

SLC2A14 SLC2A3

1.10e-052116225892112
Pubmed

CD205+ polymorphonuclear myeloid-derived suppressor cells suppress antitumor immunity by overexpressing GLUT3.

SLC2A14 SLC2A3

1.10e-052116233368883
Pubmed

Ephrin-As are required for the topographic mapping but not laminar choice of physiologically distinct RGC types.

EFNA2 EFNA5

1.10e-052116225649160
Pubmed

Neuronal functions, feeding behavior, and energy balance in Slc2a3+/- mice.

SLC2A14 SLC2A3

1.10e-052116218780771
Pubmed

Ephrin-A2 and Ephrin-A5 are important for the functional development of cutaneous innervation in a mouse model.

EFNA2 EFNA5

1.10e-052116225243788
Pubmed

Expression of mouse-GLUT3 and human-GLUT3 glucose transporter proteins in brain.

SLC2A14 SLC2A3

1.10e-05211621734877
Pubmed

Sevoflurane Induces Learning and Memory Impairment in Young Mice Through a Reduction in Neuronal Glucose Transporter 3.

SLC2A14 SLC2A3

1.10e-052116231884568
Pubmed

Expression of ephrin-A2 in the superior colliculus and EphA5 in the retina following optic nerve section in adult rat.

EFNA2 EFNA5

1.10e-052116211860487
Pubmed

Temporal and spatial distribution of murine placental and brain GLUT3-luciferase transgene as a readout of in vivo transcription.

SLC2A14 SLC2A3

1.10e-052116223193055
Pubmed

Topographic specificity within membranes of a single muscle detected in vitro.

EFNA2 EFNA5

1.10e-052116218094231
Pubmed

Gene expression of GLUT3 glucose transporter regulated by glucose in vivo in mouse brain and in vitro in neuronal cell cultures from rat embryos.

SLC2A14 SLC2A3

1.10e-05211628198523
Pubmed

Protein phosphatase 1 abrogates IRF7-mediated type I IFN response in antiviral immunity.

PPP1CA PPP1CB

1.10e-052116227469204
Pubmed

Spermiogenesis is impaired in mice bearing a targeted mutation in the protein phosphatase 1cgamma gene.

PPP1CA PPP1CC

1.10e-05211629882500
Pubmed

Altered lactate metabolism in Huntington's disease is dependent on GLUT3 expression.

SLC2A14 SLC2A3

1.10e-052116229582588
Pubmed

Auditory brainstem responses of ephrin-A2, ephrin-A5(-/-) and ephrin-A2A5(-/-) mice.

EFNA2 EFNA5

1.10e-052116224457350
Pubmed

Low-intensity repetitive transcranial magnetic stimulation requires concurrent visual system activity to modulate visual evoked potentials in adult mice.

EFNA2 EFNA5

1.10e-052116229643395
Pubmed

Placental glucose and amino acid transport in calorie-restricted wild-type and Glut3 null heterozygous mice.

SLC2A14 SLC2A3

1.10e-052116222700768
Pubmed

Glucose transporter isoform-3-null heterozygous mutation causes sexually dimorphic adiposity with insulin resistance.

SLC2A14 SLC2A3

1.10e-052116218445753
Pubmed

Sex-Specific Life Course Changes in the Neuro-Metabolic Phenotype of Glut3 Null Heterozygous Mice: Ketogenic Diet Ameliorates Electroencephalographic Seizures and Improves Sociability.

SLC2A14 SLC2A3

1.10e-052116228324109
Pubmed

Expression of the brain-type glucose transporter is restricted to brain and neuronal cells in mice.

SLC2A14 SLC2A3

1.10e-05211621516757
Pubmed

Glucose Transporter 3 Potentiates Degranulation and Is Required for Platelet Activation.

SLC2A14 SLC2A3

1.10e-052116228663252
Pubmed

Neuronal glucose transporter isoform 3 deficient mice demonstrate features of autism spectrum disorders.

SLC2A14 SLC2A3

1.10e-052116219506559
Pubmed

Protein phosphatase 1-dependent transcriptional programs for long-term memory and plasticity.

PPP1CB PPP1CC

1.10e-052116220592054
Pubmed

Canine brain glucose transporter 3: gene sequence, phylogenetic comparisons and analysis of functional sites.

SLC2A14 SLC2A3

1.10e-05211628654954
Pubmed

PP-1α and PP-1γ display antagonism and differential roles in tumorigenicity of lung cancer cells.

PPP1CA PPP1CC

1.10e-052116223176181
Pubmed

Involvement of Zizimin2/3 in the age-related defect of peritoneal B-1a cells as a source of anti-bacterial IgM.

DOCK11 DOCK10

1.10e-052116229099971
Pubmed

Identification of novel MAGE-A6- and MAGE-A12-derived HLA-A24-restricted cytotoxic T lymphocyte epitopes using an in silico peptide-docking assay.

MAGEA6 MAGEA12

1.10e-052116222707303
Pubmed

Concurrent LI-rTMS induces changes in c-Fos expression but not behavior during a progressive ratio task with adult ephrin-A2A5-/- mice.

EFNA2 EFNA5

1.10e-052116233181182
Pubmed

The role of ephrin-A2 and ephrin-A5 in sensorimotor control and gating.

EFNA2 EFNA5

1.10e-052116225200515
Pubmed

Adult glut3 homozygous null mice survive to demonstrate neural excitability and altered neurobehavioral responses reminiscent of neurodevelopmental disorders.

SLC2A14 SLC2A3

1.10e-052116233482226
Pubmed

The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation.

DOCK11 DOCK10

1.10e-052116225729399
InteractionPPP1R2C interactions

PPP1CA PPP1CB PPP1CC

7.40e-0741163int:PPP1R2C
InteractionCSRNP2 interactions

PPP1CA PPP1CB PPP1CC

1.84e-0651163int:CSRNP2
InteractionSFRP5 interactions

PPP1CA PPP1CB PPP1CC

3.67e-0661163int:SFRP5
InteractionGPR182 interactions

WASHC4 TMEM161B POMGNT1 TMEM39B HEATR1 FADS3 MDN1 AP5Z1 CCDC138 CLN6 ABCD1 PIGO

1.25e-0545511612int:GPR182
InteractionUBXN2A interactions

LACTB PPP1CA PPP1CB PPP1CC

1.41e-05261164int:UBXN2A
InteractionRYR2 interactions

PPP1CA PPP1CB PPP1CC PRKACA RASAL1

2.08e-05581165int:RYR2
InteractionRAC1 interactions

ABCC1 SLC4A7 DOCK11 ATP13A1 SLITRK4 SLC2A14 PREX2 PPP1CC PTPN1 EFNA4 MDN1 CDC123 PRKACA DOCK7 VAV3 HADHB FMNL1 SOS1

3.61e-05106311618int:RAC1
InteractionPPP1R3C interactions

MYO1C PPP1CA PPP1CB PPP1CC

3.75e-05331164int:PPP1R3C
InteractionPPP1R1B interactions

PPP1CA PPP1CC PRKACA

3.94e-05121163int:PPP1R1B
InteractionPPP1R12B interactions

ANK2 PPP1CA PPP1CB PPP1CC DNPEP

4.52e-05681165int:PPP1R12B
InteractionPPP1R2B interactions

PPP1CA PPP1CB PPP1CC

6.46e-05141163int:PPP1R2B
Cytoband2q32.3

DNAH7 HECW2

4.11e-041211622q32.3
Cytoband3p22

SLC4A7 CCR8

4.85e-041311623p22
Cytoband2p21

MSH2 LHCGR SOS1

5.08e-046111632p21
Cytoband6p23

CD83 FAM8A1

6.50e-041511626p23
Cytoband2p23

PPP1CB HADHB

8.40e-041711622p23
Cytoband19p13.11

CPAMD8 ATP13A1 ANO8

8.59e-0473116319p13.11
CytobandXq28

MAGEA3 MAGEA6 MAGEA12 ABCD1

1.07e-031761164Xq28
GeneFamilyEphrins

EFNA2 EFNA4 EFNA5

6.56e-068903546
GeneFamilyProtein phosphatase catalytic subunits|EF-hand domain containing

PPP1CA PPP1CB PPP1CC

3.29e-0513903693
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PREX2 TIAM2 VAV3 SOS1

3.27e-0466904722
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DOCK11 DOCK10 TIAM2 VAV3 RASAL1 SOS1

5.72e-04206906682
GeneFamilyMAGE family

MAGEA3 MAGEA6 MAGEA12

1.03e-03409031136
GeneFamilyBPI fold containing

BPI BPIFB2

2.81e-0316902456
ToppCellCV-Mild-7|Mild / Virus stimulation, Condition and Cluster

WASHC4 TMEM161B HEATR1 ZC3H6 CCDC138 USP40 FAM8A1

3.61e-071731167c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCellCOVID-19-kidney-CD-IC-A|COVID-19 / Disease (COVID-19 only), tissue and cell type

CPAMD8 GCGR NRXN3 EFNA5 CLCNKB ABCA5 HS6ST3

4.05e-07176116745028197364c64e93e3ffe86aff773d47a477d49
ToppCellCOVID-19-kidney-CD-IC-A|kidney / Disease (COVID-19 only), tissue and cell type

CPAMD8 DOCK10 NRXN3 EFNA5 CLCNKB ABCA5 HS6ST3

5.27e-0718311675c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A7 ANK2 NEK10 GCGR CD83 EFNA5 CLCNKB

6.09e-07187116785e58a312fc325e4063a2d250666b99b8f99beb6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A7 ANK2 NEK10 GCGR CD83 EFNA5 CLCNKB

6.09e-07187116752b5b38bef3cc06487cf42c6fb22fb33f0c7ce2b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HNF1B SLC4A7 ANK2 NEK10 EFNA5 VAV3 RASAL1

8.35e-071961167c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellCOPD-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

ABCC1 SLC4A7 NEK10 DOCK10 SLC2A3 PPP1CB PTPN1

8.35e-071961167c9bdd505c3ab380ed7b272aa518df31a0a706a06
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBXO40 CPAMD8 EFNA2 NRXN3 ABCA5 HS6ST3

8.99e-0712411661fec6663cea40017438ead397b3bf8b3cdb67e58
ToppCellCV-Mild-7|CV / Virus stimulation, Condition and Cluster

WASHC4 TMEM161B HEATR1 ZC3H6 CCDC138 FAM8A1

5.60e-06170116625ebde7d2f8ae1afdfaf5876284ff20bb179eb10
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 DOCK10 NRXN3 EFNA5 ABCA5 HS6ST3

6.62e-06175116677c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 DOCK10 NRXN3 CLCNKB ABCA5 HS6ST3

6.84e-06176116625ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 DOCK10 NRXN3 EFNA5 ABCA5 HS6ST3

7.53e-061791166e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLITRK4 CD83 DENND3 SLC2A3 EFNA5 SENP7

7.77e-061801166cf7d8bf9eee2dfab2c8a6780e296b05ad42041bf
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK10 GRID1 CPED1 TGFBR3 EFNA5 PODN

8.54e-0618311667eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 GRID1 CPED1 NRXN3 TMEM131L HS6ST3

9.09e-06185116651dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 DOCK10 NRXN3 CLCNKB ABCA5 HS6ST3

9.09e-0618511669438097e94219c1db922b8507e3a29106d32a923
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PREX2 TGFBR3 BOK EFNA5 PIK3C2B HECW2

9.09e-061851166bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 GRID1 CPED1 NRXN3 TMEM131L HS6ST3

9.09e-061851166a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 GRID1 CPED1 NRXN3 TMEM131L HS6ST3

9.66e-061871166ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 GRID1 CPED1 NRXN3 TMEM131L HS6ST3

9.66e-061871166530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 NRXN3 CLCNKB ABCA5 HADHB HS6ST3

1.09e-051911166feec8617678b778475747ad406c80231e07fd6f7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 GRID1 CPED1 NRXN3 TMEM131L HS6ST3

1.12e-05192116624e2f15f5767a97eb3b389922bcfd7b13805e1ce
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

WASHC4 MYO1C CD83 PWWP2B TMEM131L VAV3

1.19e-051941166d852aebf7a763b9a776c4570711f0c759f591910
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 ADGRB3 PREX2 SLC2A3 PIK3C2B HECW2

1.26e-0519611664cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 ADGRB3 PREX2 SLC2A3 PIK3C2B HECW2

1.26e-051961166d37f714d4fb57e958f3738fdda085560813e5bb5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HNF1B SLC4A7 ANK2 DNAH7 EFNA5 VAV3

1.26e-051961166eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRB3 B3GALT5 EFNA5 ABCA5 BPIFB2 RASAL1

1.41e-052001166682960e28542a3d6c119047cd0131941932cfdea
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CPAMD8 ANK2 CPED1 PREX2 TGFBR3 PODN

1.41e-052001166c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_cell-B_naive|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK11 SLITRK4 DOCK10 CD83 SLC2A3 VAV3

1.41e-0520011664f7be296be0cd54cfc62cc93263fde26210c61f4
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HECW1 GRID1 CPED1 PREX2 BMP4 PODN

1.41e-05200116658b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellSevere-B_intermediate-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WASHC4 TUT7 SLC2A14 GRID1 TMEM131L

1.99e-05126116542a0bdbe18ef85146cac4e86b2b27d0b3b20d8a2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PRSS35 SLC9A4 EFNA5 CLCNKB PODN

2.77e-05135116552b5c664c0b7a303c6084d508748dcb6c38a0c23
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

B3GALT5 TMC4 CAPN13 NRXN3 EFNA5

4.89e-0515211651b2a39ae159e79f1fb18d6d164bd7acab5299fca
ToppCellE17.5-Hematopoietic-Erythroid-enucleate_erythrocyte|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NEK10 TRIM10 PPP1CB BNIP3L

6.28e-058211648917c6fd4a6e3cb7a3a2af489ccc3fdc55c26698
ToppCellE17.5-Hematopoietic-Erythroid|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NEK10 TRIM10 PPP1CB BNIP3L

6.28e-05821164e0b12b9fb3cd56902b068dc0d921241481aa70a9
ToppCellControl-B_intermediate-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WASHC4 TUT7 EFNA2 MDN1 TMEM131L

7.63e-051671165948504367ecf58144d9dd74d2ec531358fc4b309
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 NRXN3 EFNA5 ABCA5 HS6ST3

7.63e-051671165edc5f04584b44f99ff9a62bbe0dab6fc044fb334
ToppCellfacs-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 CD83 PIK3C2B TMEM131L RASAL1

8.53e-051711165a31c23406cf6d6a17358a8fb41d392a7fb0306e0
ToppCellfacs-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 CD83 PIK3C2B TMEM131L RASAL1

8.53e-05171116543d8fd9b9546e84a652564fe96b514b34b06262b
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GCGR EFNA5 CLCNKB ABCA5 VAV3

9.01e-0517311650c74bdb40e635d906fd180412c23bf7fed61621e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK10 NRXN3 CLCNKB ABCA5 HS6ST3

9.26e-0517411655f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 DOCK10 NRXN3 ABCA5 HS6ST3

9.51e-05175116598947a226b5a2ac7091ff9d34243ea7736add973
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND3 TIAM2 EFNA2 BOK HECTD2

9.77e-05176116527e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS35 GRID1 CAPN13 BOK BPI

1.03e-041781165445fb243d738a34794d66f34b92dde1f3ea6738e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A7 ANK2 NEK10 CD83 EFNA5

1.09e-0418011659e09b3dfe344b5d50520711513d389865d73a861
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A7 ANK2 GCGR EFNA5 CLCNKB

1.09e-041801165eee71184ebed2694d3e60f579a44b3cf7dd2cd35
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A7 ANK2 GCGR EFNA5 CLCNKB

1.09e-041801165a17dbe03597b81e7a1fe2bf2d23e59e55c615a2a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK11 SLITRK4 DOCK10 PREX2 PODN

1.11e-04181116535bcdcd2651149692e5b150e887c0f450c81d2d4
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMC4 DENND3 PTPN1 NRXN3 FADS3

1.11e-041811165b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 DOCK10 NRXN3 ABCA5 HS6ST3

1.11e-04181116530729f0364f719c044712a51453e22dc2c1a232b
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

B3GALT5 TMC4 CAPN13 NRXN3 EFNA5

1.14e-0418211653f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A7 ANK2 GCGR EFNA5 CLCNKB

1.14e-041821165041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GCGR CLCNKB ABCA5 DOCK7 VAV3

1.17e-0418311652f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCellCOVID-19-APC-like-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

DOCK10 CD83 VAV3 FMNL1 RASAL1

1.17e-041831165703364836b42aa6ac6c68b42b700ac23c4a1afc7
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 SLITRK4 GCGR EFNA5 CLCNKB

1.17e-041831165f3728b1a51951c7349f77a3e4d2671ca3a8d2a44
ToppCellCOVID-19-APC-like|COVID-19 / group, cell type (main and fine annotations)

DOCK10 CD83 VAV3 FMNL1 RASAL1

1.17e-041831165b8f5afaf9ff1b2b1bc60be58654d1b23859dafa9
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 SLITRK4 GCGR EFNA5 CLCNKB

1.20e-0418411658939b6d795992775df0ff58ed1ec9d421a00bcc4
ToppCellControl-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

ABCC1 CPAMD8 SLC4A7 TUT7 CAPN13

1.23e-0418511656814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK10 CPED1 TGFBR3 EFNA5 PODN

1.23e-0418511653b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 SLC9A4 NRXN3 EFNA5 HS6ST3

1.23e-0418511653d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BMP4 EFNA5 FADS3 ABCA5 PIK3C2B

1.27e-041861165ffbc78058be8f0dc2e0335cc4c3195a636d17721
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BMP4 EFNA5 FADS3 ABCA5 PIK3C2B

1.27e-041861165ed924852cd7132c8f6703522037dc22bd2c83193
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 GRID1 CPED1 TMEM131L HS6ST3

1.30e-04187116548bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 NRXN3 CLCNKB ABCA5 HS6ST3

1.30e-0418711657b0168bdaa7c6c6b39878aff6a17f0943189a380
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 GRID1 CPED1 TMEM131L HS6ST3

1.30e-041871165958402fcc78f4c7a7d13d659d776f3817137975f
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRSS35 CPED1 BOK PODN HS6ST3

1.33e-041881165b382d18fb09fb2869f3c151efa71540a7f5ed229
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 GRID1 CPED1 TMEM131L HS6ST3

1.33e-041881165b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PREX2 DENND3 TGFBR3 BOK HECW2

1.33e-0418811650aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GCGR EFNA5 CLCNKB ABCA5 VAV3

1.33e-041881165bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellLV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

FBXO40 NEK10 CPED1 EFNA5 HADHB

1.33e-0418811650758b474457efa36488e0195f7357100f4b6a090
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GCGR EFNA5 CLCNKB ABCA5 VAV3

1.33e-041881165eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

HNF1B GCGR EFNA5 CLCNKB ABCA5

1.33e-0418811651d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 SLITRK4 GCGR EFNA5 CLCNKB

1.36e-041891165e127e3be626bc513e151d41812f0b7adb89d5da6
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

FBXO40 ANK2 NEK10 EFNA5 HADHB

1.36e-0418911659c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

FBXO40 ANK2 NEK10 EFNA5 HADHB

1.36e-0418911655e80c47f63980904c4c1ff02c201b67b456a0974
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 SLITRK4 GCGR EFNA5 CLCNKB

1.36e-041891165ff637ae0afdb1fdc67451be7e1e4fe575fbcfff4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 GRID1 CPED1 TMEM131L HS6ST3

1.36e-041891165fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A7 CPED1 SLC2A3 PTPN1 MDN1

1.40e-0419011651121eb607a984c59fbffe7220837fc178745aa55
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PREX2 DENND3 TGFBR3 BOK HECW2

1.40e-041901165a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCellCOVID-19-lung-Vein_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PREX2 SLC2A3 TGFBR3 PIK3C2B HECW2

1.40e-0419011651caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A7 CPED1 SLC2A3 PTPN1 MDN1

1.40e-041901165048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRSS35 BMP4 EFNA5 FADS3 ABCA5

1.40e-0419011653b9abc25b17e7295356ded57ff2ca519fa9f2686
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PREX2 DENND3 TGFBR3 BOK HECW2

1.40e-04190116525525fee1da8a808034d9c916159fd0b6b26bce8
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

FBXO40 ANK2 NEK10 EFNA5 HADHB

1.40e-041901165fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A7 NEK10 B3GALT5 EFNA5 RASAL1

1.43e-0419111653e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A7 NEK10 PPP1CB EFNA5 RASAL1

1.43e-0419111652fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCellwk_20-22-Hematologic-Myeloid-APOE+_Mac1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TWNK DENND3 C8orf82 SERPINF2 DNPEP

1.43e-041911165c204ec71b7755b46a18d3a6aa84d0f407145ce9d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A7 NEK10 NRXN3 EFNA5 RASAL1

1.43e-0419111659032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 GRID1 CPED1 TMEM131L HS6ST3

1.43e-0419111657b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A7 NEK10 NRXN3 EFNA5 RASAL1

1.43e-0419111655717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 GRID1 CPED1 TMEM131L HS6ST3

1.43e-041911165cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

FBXO40 ANK2 CPED1 EFNA5 HADHB

1.47e-041921165ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

SLC4A7 PREX2 DENND3 SLC2A3 HECW2

1.50e-041931165479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 NEK10 B3GALT5 EFNA5 RASAL1

1.54e-04194116504bfc555743f7d8821439d05ae442d15e9886c59
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HNF1B SLC9A4 EFNA5 DOCK7 RASAL1

1.54e-04194116546070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HNF1B SLC9A4 EFNA5 DOCK7 RASAL1

1.54e-041941165abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 NEK10 B3GALT5 EFNA5 RASAL1

1.54e-04194116569bff17df4a760ccf081cf52ff04af02c14f448d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 PREX2 TGFBR3 PIK3C2B HECW2

1.54e-041941165b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NRXN3 CLCNKB ABCA5 HADHB HS6ST3

1.54e-0419411656165c00ec06a8393f23b0c62f679c143839b03b1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 PREX2 TGFBR3 PIK3C2B HECW2

1.54e-041941165fa6d51f36a3dae8763a595c20892987ed454c0f0
DrugVenlafaxine Hydrochloride

ABCC1 CYP3A4 PREX2 EFNA2 EFNA5 FMNL1

5.55e-07591166ctd:D000069470
Diseaseunderweight body mass index status

ANK2 ADGRB3 NRXN3

4.28e-0691113EFO_0005936
DiseaseColorectal Carcinoma

ABCC1 CPAMD8 TTLL3 ANK2 GRID1 MSH2 PREX2 BMP4 ABCA5 BPIFB2 PIGO

7.01e-0570211111C0009402
Diseaseurinary potassium to creatinine ratio

SLC4A7 NEK10

2.08e-0461112EFO_0009882
Diseaselevel of Phosphatidylcholine (16:0_18:0) in blood serum

FADS3 DOCK7

2.08e-0461112OBA_2045069
Disease1-palmitoyl-2-linoleoyl-GPI (16:0/18:2) measurement

TMC4 DOCK7

2.91e-0471112EFO_0800609
Diseaseatrial heart septal defect (is_implicated_in)

BMP4 SOS1

2.91e-0471112DOID:1882 (is_implicated_in)
Diseaseresponse to anticonvulsant

ABCC1 ANK2 PREX2 VAV3

3.04e-04851114GO_0036277
Diseaselevel of Phosphatidylinositol (16:0_18:2) in blood serum

TMC4 DOCK7

3.87e-0481112OBA_2045153
Diseasephosphatidylinositol measurement

TMC4 PPP1CC FADS3 DOCK7

4.64e-04951114EFO_0010230
Disease1-palmitoyl-2-oleoyl-GPI (16:0/18:1) measurement

TMC4 DOCK7

4.96e-0491112EFO_0800439
Disease1-palmitoyl-2-arachidonoyl-GPI (16:0/20:4) measurement

TMC4 DOCK7

4.96e-0491112EFO_0800412
Diseaseandrostenediol (3beta,17beta) disulfate (1) measurement

CYP3A4 SULT2A1

4.96e-0491112EFO_0800278
Diseasemental or behavioural disorder

HNF1B PHF8 EFNA5 BPI ABCD1

5.92e-041791115EFO_0000677
Disease4-androsten-3alpha,17alpha-diol monosulfate (3) measurement

CYP3A4 SULT2A1

6.19e-04101112EFO_0022090
Diseasemyelodysplastic syndrome

GRID1 EFNA5

6.19e-04101112EFO_0000198
Disease1-stearoyl-2-oleoyl-GPI (18:0/18:1) measurement

TMC4 DOCK7

6.19e-04101112EFO_0800469
Disease5alpha-androstan-3beta,17alpha-diol disulfate measurement

CYP3A4 SULT2A1

6.19e-04101112EFO_0800289
DiseaseColorectal Neoplasms

ABCC1 CPAMD8 GRID1 MSH2 BMP4 ABCA5

6.44e-042771116C0009404
Diseaseglycerophospholipid measurement

TMC4 FADS3 DOCK7

8.42e-04491113EFO_0007630
Diseaselevel of Phosphatidylinositol (16:0_18:1) in blood serum

TMC4 DOCK7

9.03e-04121112OBA_2045152
Diseasecholesteryl ester 20:2 measurement

FADS3 THAP12

9.03e-04121112EFO_0021440
Diseasecataract (biomarker_via_orthology)

SLC2A14 SLC2A3

1.06e-03131112DOID:83 (biomarker_via_orthology)
DiseaseAlzheimer disease, cognitive decline measurement, Cognitive impairment

TIAM2 TXNL1

1.06e-03131112EFO_0007710, HP_0100543, MONDO_0004975
Disease1-stearoyl-2-linoleoyl-GPI (18:0/18:2) measurement

TMC4 DOCK7

1.06e-03131112EFO_0800413
Diseaseandrostenediol (3alpha, 17alpha) monosulfate (3) measurement

CYP3A4 SULT2A1

1.06e-03131112EFO_0800293
Disease1-stearoyl-2-dihomo-linolenoyl-GPI (18:0/20:3n3 or 6) measurement

TMC4 DOCK7

1.24e-03141112EFO_0022085
DiseaseX-21470 measurement

CYP3A4 SULT2A1

1.24e-03141112EFO_0800817
Diseasediacylglycerol 38:4 measurement

TMC4 FADS3

1.24e-03141112EFO_0020066
Diseasepolyp of colon

BMP4 FADS3 PIK3C2B

1.24e-03561113MONDO_0021400
Diseaselipid metabolism disorder (implicated_via_orthology)

FADS3 HADHB

1.43e-03151112DOID:3146 (implicated_via_orthology)
Disease1-stearoyl-2-arachidonoyl-GPI (18:0/20:4) measurement

TMC4 DOCK7

1.63e-03161112EFO_0800184
Diseasesuccinylcarnitine measurement

ABCC1 LACTB

1.63e-03161112EFO_0020020
Diseaselevel of Phosphatidylinositol (18:0_18:1) in blood serum

TMC4 DOCK7

2.06e-03181112OBA_2045155
Disease5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement

CYP3A4 SULT2A1

2.06e-03181112EFO_0800288
DiseaseNoonan-Like Syndrome With Loose Anagen Hair

PPP1CB SOS1

2.30e-03191112C3501846
Diseasemetabolonic lactone sulfate measurement

CYP3A4 SULT2A1

2.30e-03191112EFO_0800659
DiseaseNoonan syndrome-like disorder with loose anagen hair

PPP1CB SOS1

2.30e-03191112C1843181
DiseaseCardio-facio-cutaneous syndrome

PPP1CB SOS1

2.30e-03191112C1275081
DiseaseCostello syndrome (disorder)

PPP1CB SOS1

2.30e-03191112C0587248
Diseasediacylglycerol 38:3 measurement

TMC4 FADS3

2.30e-03191112EFO_0020065
Diseasechemokine (C-C motif) ligand 27 measurement

SLC4A7 NEK10 EFNA5

2.36e-03701113EFO_0008082
Diseaseandrosterone glucuronide measurement

CYP3A4 SULT2A1

2.55e-03201112EFO_0800317
Diseaselevel of Phosphatidylinositol (18:0_18:2) in blood serum

FADS3 DOCK7

2.81e-03211112OBA_2045156
Diseasepeak expiratory flow

UTP6 GRID1 TGFBR3 BMP4 BOK PIK3C2B CDC123

2.81e-034981117EFO_0009718
Diseaseserum metabolite measurement

ABCC1 CYP3A4 TMC4 CD83 CPED1 LACTB FADS3 SULT2A1 DOCK7 ELP2

3.03e-0394511110EFO_0005653
DiseaseLEOPARD Syndrome

PPP1CB SOS1

3.08e-03221112C0175704
DiseaseX-24947 measurement

CYP3A4 SULT2A1

3.08e-03221112EFO_0800910
Disease5alpha-androstan-3beta,17beta-diol disulfate measurement

CYP3A4 SULT2A1

3.08e-03221112EFO_0021115
Diseaselevel of Phosphatidylinositol (18:0_20:4) in blood serum

FADS3 DOCK7

3.37e-03231112OBA_2045158
Diseaselymphocyte count

ABCC1 SLC4A7 CYP3A4 DOCK10 PSMD3 PREX2 DENND3 PPP1CC PTPN1 SLC9A4 ABCD1 PPP2R3C DNPEP

3.43e-03146411113EFO_0004587
Diseasecancer (implicated_via_orthology)

MSH2 PPP1CA PPP1CB PPP1CC TSPAN17

3.49e-032681115DOID:162 (implicated_via_orthology)
DiseaseNoonan Syndrome

PPP1CB SOS1

3.67e-03241112C0028326

Protein segments in the cluster

PeptideGeneStartEntry
FPQSSSIVIFLLFFL

ABCA5

291

Q8WWZ7
CFKDPQFLVTFFSRL

C8orf82

66

Q6P1X6
TLFKGFFELFPSLSH

DNPEP

466

Q9ULA0
KLQTFFETFLRASSP

CPED1

306

A4D0V7
LSSFSVNRPFLFFIF

SERPINF2

406

P08697
SFFEFLVLNKVSPSQ

ADGRB3

151

O60242
ELFKERATAPFFVFQ

ATP13A1

236

Q9HD20
TTRFFTGFLKLNEFP

B3GALT5

176

Q9Y2C3
QRFREKFPPVFFSSF

CAPN13

416

Q6MZZ7
STLRLSFPNLFKFLA

AP5Z1

426

O43299
SKFSLLSVNPVEFFR

ANGEL2

261

Q5VTE6
FKDTSTSFLAFQLLP

DENND3

1071

A2RUS2
SAFRFLFNLSSIPEN

BMP4

136

P12644
SFGRFLKAAFFVLLP

BOK

196

Q9UMX3
LSLISKFRFNFLAPE

HADHB

196

P55084
GSDTRLPAFLSFKFL

ANO8

1016

Q9HCE9
SGFLFLRFFAPAILT

RASAL1

466

O95294
ILARAFSRFPSFLKA

RBM42

396

Q9BTD8
LSFEFLSLPSFSEKL

UROS

36

P10746
TAVRKFFFFLDPLRT

PPP2R3C

221

Q969Q6
VFLTANVLRAFSPKF

ABCD1

251

P33897
FSFFAFKENRLPLFV

ANK2

1401

Q01484
FTCKFARLQSIFPDF

CD83

161

Q01151
PSREFFFLVSRELFN

HECW2

1261

Q9P2P5
AFDSTPNLKGIFLRF

PODN

541

Q7Z5L7
ESPASFLNFLFKVRE

PTPN1

186

P18031
FPFLVKLEFSFKDNS

PRKACA

101

P17612
FKDTSPVFQRLFLES

MDN1

116

Q9NU22
FTKTFQRDFFLLLSK

LHCGR

626

P22888
FFPVIFSKASSSLQL

MAGEA3

146

P43357
FFPVIFSKASDSLQL

MAGEA6

146

P43360
RNFQDFFPVIFSKAS

MAGEA12

141

P43365
SREFFFLLSQELFNP

HECW1

1296

Q76N89
SIESLRLFKNDPLFF

LACTB

301

P83111
LTTFDSFPELNAAFK

HECTD2

156

Q5U5R9
SSVFFNKLAFLPRSN

C9orf131

226

Q5VYM1
LRFDFLDPFFLSITV

CYP3A4

211

P08684
FKRLFPTDLFEIFID

NEK10

456

Q6ZWH5
RPFCSFSVDKIFSLF

OR4Q3

261

Q8NH05
KIQRFTPFSLGFEFL

EFNA4

111

P52798
KLFFDLFLSSFQGLL

GCGR

381

P47871
FFQFKTTSPDGFILF

NRXN3

896

Q9Y4C0
VFPLEFNKNSLTFSI

TWNK

616

Q96RR1
FLFAVLFFLTPAKNA

DEFB106A

6

Q8N104
FLAFTFFKVPETRGR

SLC2A14

466

Q8TDB8
QFLFERTFNLKFISP

HS6ST3

361

Q8IZP7
RTFNLKFISPFTQFN

HS6ST3

366

Q8IZP7
KFISPFTQFNITRAS

HS6ST3

371

Q8IZP7
LQIDFPTSAFDIKFT

PIK3C2B

781

O00750
TRKSTQSDLAFFRFP

THAP12

11

O43422
EFFAKRQLVTLFSAP

PPP1CA

256

P62136
FFAKRQLVTLFSAPN

PPP1CB

256

P62140
FFLKPTFKNFFTLVS

PCDHB14

391

Q9Y5E9
AAFFKSSNLPLRFLS

CCDC138

481

Q96M89
SLRLFVCKFPSAFFQ

DOCK10

1541

Q96BY6
VFASLRAFISKFPSA

DOCK11

1456

Q5JSL3
SFRPATLTVTNFFKQ

DOCK7

461

Q96N67
FLLFKSSDFITRDFT

CDC123

131

O75794
NLALSDLLFVFSFPF

CCR8

76

P51685
KFRLTTKFFGTFLPE

BPI

321

P17213
LKSFAQARSFIFVDP

CPAMD8

1216

Q8IZJ3
LFFPRFFFLSNDELL

DNAH7

1066

Q8WXX0
FSAEFLKVFIPSLFL

BNIP3L

181

O60238
TFTCNKFFRRDEFPL

FBXO40

476

Q9UH90
TSPGLFFSLFSRFIK

FMNL1

981

O95466
FSEKFQLFTPFSLGF

EFNA2

126

O43921
PLKFSEKFQLFTPFS

EFNA5

111

P52803
TFLAFTFFKVPETRG

SLC2A3

441

P11169
KISIFSLFAPFDFAV

GRID1

551

Q9ULK0
KLSEVTFRPLFFKLF

HEATR1

1906

Q9H583
FEPVFSLFAFTNKIT

ELP2

651

Q6IA86
KLFDASPTFFAFLLG

FADS3

126

Q9Y5Q0
ISKLSPFSEFFKLRF

PWWP2B

541

Q6NUJ5
FVTPLTDLRSDFSKF

MSH2

436

P43246
ALIKNFSIASFFPAF

FAM8A1

371

Q9UBU6
FTIFIKNSIRFPLFN

P2RX3

171

P56373
TAFVSLALFNILRFP

ABCC1

581

P33527
KSSQDQLLFLFPEFS

HNF1B

196

P35680
FLTRQAFAKVFNTTP

RTCB

326

Q9Y3I0
LISFLPDNIFRFASL

SLITRK4

166

Q8IW52
VFKSLQESRPFSVDF

UTP6

496

Q9NYH9
FPLFQNLSSKESSFI

SENP7

661

Q9BQF6
RKAPFFLSDFKDALS

SLC4A7

591

Q9Y6M7
SKESESFVFFLPRLI

TMEM131L

571

A2VDJ0
SPVSKLTFKFFLAIF

TMEM161B

221

Q8NDZ6
TFSFCRLFEKRPAQF

LRRC41

676

Q15345
LTATFNLFPEAKFAV

POMGNT1

376

Q8WZA1
FRTFPFSIKDQCIIF

SLC9A4

411

Q6AI14
KFFPFNLLDFESFDL

PTTG2

116

Q9NZH5
LLDFFFISEPLFKLS

SCGB1D2

31

O95969
FSSHLPIQLFPKSFF

SULT2A1

96

Q06520
FREPFVSNSKLFSAN

SOS1

226

Q07889
TFFSFLRRKTDFFIG

NUDC

31

Q9Y266
LLAAANFTFKVFRAP

BPIFB2

91

Q8N4F0
KRLFLDSNGLFLFSS

CLN6

251

Q9NWW5
FFGFIRNNRFSSKLL

CLCNKB

306

P51801
NSSKILRFISDFLAF

ATP11B

331

Q9Y2G3
LRENTFLLKFFSVFL

TSPAN17

86

Q96FV3
QTDFSDDFRKIPSLF

ZC3H6

416

P61129
FTSNNATRDFLLPFL

PSMD3

121

O43242
FNTLETPSQFRKLLF

TIAM2

1171

Q8IVF5
FSILDKRFLTNFPFS

PRSS35

131

Q8N3Z0
TFRASAANFFFPLVL

TMC4

581

Q7Z404
KSEFKDEPLLFRFFS

PREX2

551

Q70Z35
FQPSQLFDFDDLLKF

TTLL3

81

Q9Y4R7
EFFAKRQLVTLFSAP

PPP1CC

256

P36873
FTASFTRKVIPFFGL

TRIM10

456

Q9UDY6
DLALFFSLNPIRFFN

WASHC4

706

Q2M389
SKAFFFPSFNVRDLD

PIGO

191

Q8TEQ8
EKRLSTADLFRFPNF

PHF8

386

Q9UPP1
SFIRQDFPGTKLSLF

TUT7

1031

Q5VYS8
FLTVSLLRFNFDFVK

USP40

241

Q9NVE5
KRFSFVFKPVFNTSL

TGFBR3

686

Q03167
FHFFFSKPLRILNIL

TMEM39B

411

Q9GZU3
KFVPFSFSLLSSKFN

ATP6V0A2

836

Q9Y487
NNISATPTFLFFRNK

TXNL1

71

O43396
PLKRFLTAAEFDSVF

VAV3

221

Q9UKW4
FIRFPKTLFATEDAL

MYO1C

716

O00159
FPRALIFSTDDFFFR

N4BP2L1

66

Q5TBK1