| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | protein serine kinase activity | 1.00e-03 | 363 | 25 | 4 | GO:0106310 | |
| GeneOntologyMolecularFunction | protein serine/threonine kinase activity | 2.14e-03 | 446 | 25 | 4 | GO:0004674 | |
| GeneOntologyMolecularFunction | kinase activity | 2.27e-03 | 764 | 25 | 5 | GO:0016301 | |
| GeneOntologyMolecularFunction | transferase activity, transferring phosphorus-containing groups | 5.48e-03 | 938 | 25 | 5 | GO:0016772 | |
| GeneOntologyMolecularFunction | protein kinase activity | 6.18e-03 | 600 | 25 | 4 | GO:0004672 | |
| GeneOntologyBiologicalProcess | synaptic vesicle uncoating | 5.49e-08 | 7 | 25 | 3 | GO:0016191 | |
| GeneOntologyBiologicalProcess | clathrin coat disassembly | 8.77e-08 | 8 | 25 | 3 | GO:0072318 | |
| GeneOntologyBiologicalProcess | vesicle uncoating | 1.31e-07 | 9 | 25 | 3 | GO:0072319 | |
| GeneOntologyBiologicalProcess | synaptic vesicle endocytosis | 2.09e-04 | 96 | 25 | 3 | GO:0048488 | |
| GeneOntologyBiologicalProcess | presynaptic endocytosis | 2.50e-04 | 102 | 25 | 3 | GO:0140238 | |
| GeneOntologyBiologicalProcess | plasma membrane tubulation | 2.64e-04 | 20 | 25 | 2 | GO:0097320 | |
| GeneOntologyBiologicalProcess | regulation of clathrin-dependent endocytosis | 2.92e-04 | 21 | 25 | 2 | GO:2000369 | |
| GeneOntologyBiologicalProcess | synaptic vesicle recycling | 3.20e-04 | 111 | 25 | 3 | GO:0036465 | |
| GeneOntologyBiologicalProcess | protein depolymerization | 6.85e-04 | 144 | 25 | 3 | GO:0051261 | |
| GeneOntologyCellularComponent | FAR/SIN/STRIPAK complex | 1.70e-04 | 17 | 24 | 2 | GO:0090443 | |
| Domain | BAR | 2.83e-09 | 15 | 24 | 4 | PF03114 | |
| Domain | BAR | 2.83e-09 | 15 | 24 | 4 | SM00721 | |
| Domain | BAR_dom | 3.78e-09 | 16 | 24 | 4 | IPR004148 | |
| Domain | BAR | 8.02e-09 | 19 | 24 | 4 | PS51021 | |
| Domain | - | 5.62e-08 | 30 | 24 | 4 | 1.20.1270.60 | |
| Domain | AH/BAR-dom | 5.62e-08 | 30 | 24 | 4 | IPR027267 | |
| Domain | Spectrin_alpha_SH3 | 8.40e-07 | 15 | 24 | 3 | IPR013315 | |
| Domain | SH3_1 | 1.17e-03 | 164 | 24 | 3 | PF00018 | |
| Domain | SH3 | 2.58e-03 | 216 | 24 | 3 | PS50002 | |
| Domain | SH3 | 2.58e-03 | 216 | 24 | 3 | SM00326 | |
| Domain | SH3_domain | 2.72e-03 | 220 | 24 | 3 | IPR001452 | |
| Domain | Znf_C2H2-like | 3.00e-03 | 796 | 24 | 5 | IPR015880 | |
| Domain | Znf_C2H2 | 3.15e-03 | 805 | 24 | 5 | IPR007087 | |
| Domain | ZnF_C2H2 | 3.20e-03 | 808 | 24 | 5 | SM00355 | |
| Domain | Kinase-like_dom | 4.70e-03 | 542 | 24 | 4 | IPR011009 | |
| Domain | SH3_2 | 5.42e-03 | 86 | 24 | 2 | IPR011511 | |
| Domain | SH3_2 | 5.42e-03 | 86 | 24 | 2 | PF07653 | |
| Domain | - | 1.03e-02 | 679 | 24 | 4 | 3.30.160.60 | |
| Domain | Ser/Thr_kinase_AS | 1.04e-02 | 357 | 24 | 3 | IPR008271 | |
| Domain | KRAB | 1.05e-02 | 358 | 24 | 3 | PS50805 | |
| Domain | KRAB | 1.05e-02 | 358 | 24 | 3 | PF01352 | |
| Domain | S_TKc | 1.06e-02 | 359 | 24 | 3 | SM00220 | |
| Domain | PROTEIN_KINASE_ST | 1.08e-02 | 362 | 24 | 3 | PS00108 | |
| Domain | zf-C2H2 | 1.11e-02 | 693 | 24 | 4 | PF00096 | |
| Domain | Znf_C2H2/integrase_DNA-bd | 1.11e-02 | 694 | 24 | 4 | IPR013087 | |
| Domain | KRAB | 1.14e-02 | 369 | 24 | 3 | SM00349 | |
| Domain | KRAB | 1.15e-02 | 370 | 24 | 3 | IPR001909 | |
| Domain | Pkinase | 1.24e-02 | 381 | 24 | 3 | PF00069 | |
| Domain | ZINC_FINGER_C2H2_2 | 1.61e-02 | 775 | 24 | 4 | PS50157 | |
| Domain | ZINC_FINGER_C2H2_1 | 1.63e-02 | 777 | 24 | 4 | PS00028 | |
| Domain | PROTEIN_KINASE_ATP | 2.03e-02 | 459 | 24 | 3 | PS00107 | |
| Pathway | REACTOME_INLB_MEDIATED_ENTRY_OF_LISTERIA_MONOCYTOGENES_INTO_HOST_CELL | 1.10e-06 | 15 | 20 | 3 | M27774 | |
| Pathway | REACTOME_LISTERIA_MONOCYTOGENES_ENTRY_INTO_HOST_CELLS | 2.74e-06 | 20 | 20 | 3 | M27780 | |
| Pathway | REACTOME_NEGATIVE_REGULATION_OF_MET_ACTIVITY | 3.20e-06 | 21 | 20 | 3 | MM15347 | |
| Pathway | REACTOME_NEGATIVE_REGULATION_OF_MET_ACTIVITY | 3.20e-06 | 21 | 20 | 3 | M27645 | |
| Pathway | REACTOME_EGFR_DOWNREGULATION | 1.07e-05 | 31 | 20 | 3 | MM14705 | |
| Pathway | REACTOME_EGFR_DOWNREGULATION | 1.07e-05 | 31 | 20 | 3 | M16597 | |
| Pathway | REACTOME_SIGNALING_BY_EGFR | 4.32e-05 | 49 | 20 | 3 | MM14695 | |
| Pathway | REACTOME_SIGNALING_BY_EGFR | 5.47e-05 | 53 | 20 | 3 | M27039 | |
| Pathway | REACTOME_SIGNALING_BY_MET | 1.10e-04 | 67 | 20 | 3 | MM15345 | |
| Pathway | REACTOME_BACTERIAL_INFECTION_PATHWAYS | 1.31e-04 | 71 | 20 | 3 | M48033 | |
| Pathway | REACTOME_SIGNALING_BY_MET | 1.80e-04 | 79 | 20 | 3 | M27643 | |
| Pathway | REACTOME_CARGO_RECOGNITION_FOR_CLATHRIN_MEDIATED_ENDOCYTOSIS | 3.83e-04 | 102 | 20 | 3 | MM15498 | |
| Pathway | REACTOME_CARGO_RECOGNITION_FOR_CLATHRIN_MEDIATED_ENDOCYTOSIS | 4.17e-04 | 105 | 20 | 3 | M27752 | |
| Pathway | REACTOME_CLATHRIN_MEDIATED_ENDOCYTOSIS | 1.01e-03 | 142 | 20 | 3 | MM15499 | |
| Pathway | REACTOME_CLATHRIN_MEDIATED_ENDOCYTOSIS | 1.07e-03 | 145 | 20 | 3 | M27753 | |
| Pathway | REACTOME_NONHOMOLOGOUS_END_JOINING_NHEJ | 1.99e-03 | 47 | 20 | 2 | MM15296 | |
| Pathway | KEGG_ENDOCYTOSIS | 2.02e-03 | 181 | 20 | 3 | M1519 | |
| Pubmed | Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin. | 1.31e-09 | 4 | 25 | 3 | 32152276 | |
| Pubmed | 1.31e-09 | 4 | 25 | 3 | 9122235 | ||
| Pubmed | 1.31e-09 | 4 | 25 | 3 | 10816441 | ||
| Pubmed | Synaptojanin and Endophilin Mediate Neck Formation during Ultrafast Endocytosis. | 1.31e-09 | 4 | 25 | 3 | 29953872 | |
| Pubmed | LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis. | 1.31e-09 | 4 | 25 | 3 | 22998870 | |
| Pubmed | 3.28e-09 | 5 | 25 | 3 | 27720640 | ||
| Pubmed | 3.28e-09 | 5 | 25 | 3 | 12034747 | ||
| Pubmed | 3.28e-09 | 5 | 25 | 3 | 25471590 | ||
| Pubmed | Binding properties of SH3 peptide ligands identified from phage-displayed random peptide libraries. | 6.55e-09 | 6 | 25 | 3 | 9238627 | |
| Pubmed | Role of dynamin, synaptojanin, and endophilin in podocyte foot processes. | 6.55e-09 | 6 | 25 | 3 | 23187129 | |
| Pubmed | 6.55e-09 | 6 | 25 | 3 | 10764144 | ||
| Pubmed | A novel SH3-containing human gene family preferentially expressed in the central nervous system. | 6.55e-09 | 6 | 25 | 3 | 9169142 | |
| Pubmed | 1.15e-08 | 7 | 25 | 3 | 25771685 | ||
| Pubmed | 1.15e-08 | 7 | 25 | 3 | 10542231 | ||
| Pubmed | 1.15e-08 | 7 | 25 | 3 | 9341169 | ||
| Pubmed | 1.83e-08 | 8 | 25 | 3 | 20064468 | ||
| Pubmed | 1.83e-08 | 8 | 25 | 3 | 16115810 | ||
| Pubmed | 1.83e-08 | 8 | 25 | 3 | 22099461 | ||
| Pubmed | The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met. | 5.39e-08 | 11 | 25 | 3 | 11894096 | |
| Pubmed | 5.39e-08 | 11 | 25 | 3 | 12456676 | ||
| Pubmed | Cloning of ligand targets: systematic isolation of SH3 domain-containing proteins. | 1.48e-07 | 15 | 25 | 3 | 9630982 | |
| Pubmed | Mst3b, an Ste20-like kinase, regulates axon regeneration in mature CNS and PNS pathways. | 4.96e-07 | 2 | 25 | 2 | 19855390 | |
| Pubmed | 4.96e-07 | 2 | 25 | 2 | 35130716 | ||
| Pubmed | Genetic mapping of eight SH3 domain genes on seven mouse chromosomes. | 1.06e-06 | 28 | 25 | 3 | 10087302 | |
| Pubmed | 1.49e-06 | 3 | 25 | 2 | 15919751 | ||
| Pubmed | 1.49e-06 | 3 | 25 | 2 | 21426302 | ||
| Pubmed | 1.49e-06 | 3 | 25 | 2 | 10535961 | ||
| Pubmed | 1.49e-06 | 3 | 25 | 2 | 22167186 | ||
| Pubmed | 1.49e-06 | 3 | 25 | 2 | 23889253 | ||
| Pubmed | 2.97e-06 | 4 | 25 | 2 | 36692953 | ||
| Pubmed | 2.97e-06 | 4 | 25 | 2 | 24637776 | ||
| Pubmed | 2.97e-06 | 4 | 25 | 2 | 9238017 | ||
| Pubmed | Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PK. | 2.97e-06 | 4 | 25 | 2 | 19851285 | |
| Pubmed | 4.95e-06 | 5 | 25 | 2 | 14551139 | ||
| Pubmed | Calmodulin Promotes N-BAR Domain-Mediated Membrane Constriction and Endocytosis. | 4.95e-06 | 5 | 25 | 2 | 27093085 | |
| Pubmed | Endophilin, Lamellipodin, and Mena cooperate to regulate F-actin-dependent EGF-receptor endocytosis. | 7.43e-06 | 6 | 25 | 2 | 24076656 | |
| Pubmed | 7.43e-06 | 6 | 25 | 2 | 28235806 | ||
| Pubmed | Pdcd10-Stk24/25 complex controls kidney water reabsorption by regulating Aqp2 membrane targeting. | 7.43e-06 | 6 | 25 | 2 | 34156031 | |
| Pubmed | CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations. | 7.43e-06 | 6 | 25 | 2 | 17657516 | |
| Pubmed | 8.24e-06 | 1084 | 25 | 7 | 11544199 | ||
| Pubmed | CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation. | 1.04e-05 | 7 | 25 | 2 | 20332113 | |
| Pubmed | 1.04e-05 | 7 | 25 | 2 | 22291017 | ||
| Pubmed | Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors. | 1.39e-05 | 8 | 25 | 2 | 11894095 | |
| Pubmed | Ataxin-2 associates with the endocytosis complex and affects EGF receptor trafficking. | 1.39e-05 | 8 | 25 | 2 | 18602463 | |
| Pubmed | CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases. | 1.78e-05 | 9 | 25 | 2 | 12177062 | |
| Pubmed | STK25 and MST3 Have Overlapping Roles to Regulate Rho GTPases during Cortical Development. | 1.78e-05 | 9 | 25 | 2 | 34518307 | |
| Pubmed | 2.06e-05 | 74 | 25 | 3 | 29795351 | ||
| Pubmed | 2.22e-05 | 10 | 25 | 2 | 17478428 | ||
| Pubmed | 2.22e-05 | 10 | 25 | 2 | 20949042 | ||
| Pubmed | Phosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase Itch. | 3.85e-05 | 13 | 25 | 2 | 23146885 | |
| Pubmed | Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. | 5.92e-05 | 16 | 25 | 2 | 16096065 | |
| Pubmed | 5.92e-05 | 16 | 25 | 2 | 24793032 | ||
| Pubmed | 1.24e-04 | 23 | 25 | 2 | 18391950 | ||
| Pubmed | Next-generation sequencing to generate interactome datasets. | 1.31e-04 | 1147 | 25 | 6 | 21516116 | |
| Pubmed | 3.25e-04 | 37 | 25 | 2 | 19266077 | ||
| Pubmed | 4.63e-04 | 513 | 25 | 4 | 25798074 | ||
| Pubmed | MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation. | 4.91e-04 | 216 | 25 | 3 | 32640226 | |
| Pubmed | 5.04e-04 | 46 | 25 | 2 | 18782753 | ||
| Pubmed | A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase. | 6.05e-04 | 232 | 25 | 3 | 25515538 | |
| Interaction | PRR5-ARHGAP8 interactions | 2.01e-07 | 10 | 25 | 3 | int:PRR5-ARHGAP8 | |
| Interaction | MAP4K3 interactions | 3.65e-06 | 86 | 25 | 4 | int:MAP4K3 | |
| Interaction | ARHGAP8 interactions | 6.70e-06 | 30 | 25 | 3 | int:ARHGAP8 | |
| Interaction | DPYSL4 interactions | 6.08e-05 | 62 | 25 | 3 | int:DPYSL4 | |
| Interaction | C4orf19 interactions | 8.07e-05 | 11 | 25 | 2 | int:C4orf19 | |
| Interaction | AMPH interactions | 9.50e-05 | 72 | 25 | 3 | int:AMPH | |
| Interaction | FBXO32 interactions | 9.73e-05 | 386 | 25 | 5 | int:FBXO32 | |
| Interaction | SH3GL2 interactions | 1.73e-04 | 88 | 25 | 3 | int:SH3GL2 | |
| Interaction | PDCD6IP interactions | 1.82e-04 | 233 | 25 | 4 | int:PDCD6IP | |
| Interaction | ADRB1 interactions | 2.77e-04 | 20 | 25 | 2 | int:ADRB1 | |
| Interaction | PDCD10 interactions | 2.83e-04 | 104 | 25 | 3 | int:PDCD10 | |
| Interaction | SYNJ1 interactions | 2.99e-04 | 106 | 25 | 3 | int:SYNJ1 | |
| Interaction | EGFL6 interactions | 3.06e-04 | 21 | 25 | 2 | int:EGFL6 | |
| Interaction | LRRK2 interactions | 3.13e-04 | 496 | 25 | 5 | int:LRRK2 | |
| Interaction | EIF5AL1 interactions | 3.36e-04 | 22 | 25 | 2 | int:EIF5AL1 | |
| Interaction | AZU1 interactions | 3.68e-04 | 23 | 25 | 2 | int:AZU1 | |
| Interaction | RIPOR1 interactions | 4.01e-04 | 24 | 25 | 2 | int:RIPOR1 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr19p13 | 8.53e-04 | 797 | 25 | 4 | chr19p13 | |
| Cytoband | 19p13.2 | 6.89e-03 | 229 | 25 | 2 | 19p13.2 | |
| Cytoband | 19p13.3 | 7.36e-03 | 237 | 25 | 2 | 19p13.3 | |
| GeneFamily | N-BAR domain containing | 3.39e-10 | 12 | 18 | 4 | 1289 | |
| GeneFamily | Protein phosphatase catalytic subunits|STRIPAK complex | 1.76e-04 | 20 | 18 | 2 | 1371 | |
| GeneFamily | Zinc fingers C2H2-type|ZF class homeoboxes and pseudogenes | 4.84e-03 | 718 | 18 | 4 | 28 | |
| GeneFamily | WD repeat domain containing | 2.75e-02 | 262 | 18 | 2 | 362 | |
| Disease | cerebral cavernous malformation (implicated_via_orthology) | 3.77e-05 | 11 | 25 | 2 | DOID:0060669 (implicated_via_orthology) | |
| Disease | Inherited neuropathies | 5.27e-04 | 40 | 25 | 2 | C0598589 | |
| Disease | oral squamous cell carcinoma (is_marker_for) | 1.30e-03 | 63 | 25 | 2 | DOID:0050866 (is_marker_for) | |
| Disease | Myocardial Infarction | 2.93e-03 | 95 | 25 | 2 | C0027051 | |
| Disease | stomach cancer (is_marker_for) | 6.42e-03 | 142 | 25 | 2 | DOID:10534 (is_marker_for) |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| KEKRRHRSHSAEGGK | 106 | P21127 | |
| YLHGLHKKSDGRRDK | 96 | P56555 | |
| KRGRKLVDYDSARHH | 141 | Q9UBW5 | |
| REKKFGLIDHLHYSR | 686 | Q6NSI4 | |
| KGEERHKEKRHKEGF | 251 | Q8WVS4 | |
| KHLDRHSDSKQGKYL | 41 | Q13315 | |
| AHRDYKKLAAVHGKL | 1716 | Q96HP0 | |
| AYHEGREKRHRKKLY | 96 | Q6PEY0 | |
| RKGAKFRKYIGHSAH | 551 | Q05BV3 | |
| EKALGKHKERIGHRY | 166 | P52597 | |
| GLLHGEEDYLKRHKS | 876 | Q9P2F6 | |
| HHLKKLEGRRLDYDY | 156 | Q99963 | |
| RHGGYKPTDKHKTDL | 96 | P06732 | |
| LKGLDYLHSEKKIHR | 141 | Q9Y6E0 | |
| KGLDYLHSERKIHRD | 126 | O00506 | |
| GHFRLKKLLKDHASS | 371 | Q9NUW8 | |
| HHLKKLEGRRLDFDY | 156 | Q99961 | |
| YREHLGGQKHRKKEA | 286 | Q9UPR6 | |
| KYKERGKAFTRGLHL | 266 | Q8TB69 | |
| HHLKKLEGRRLDFDY | 156 | Q99962 | |
| YAKKNEPKHRLARHG | 81 | P62847 | |
| EPKHRLARHGLYEKK | 86 | P62847 | |
| LARHRKIHTGEKLYK | 606 | Q76KX8 | |
| RGAEALKGAHKYERK | 1836 | Q9UKX3 | |
| IRRHYRDKHGGKKLF | 2206 | Q96JM2 | |
| SLKRHEKSHTGEKRY | 241 | C9JN71 |