Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-25 ERVK-9

1.18e-0837415GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-25 ERVK-9

1.35e-0838415GO:0070001
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-8 ERVK-6

2.24e-0411412GO:0004523
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-25 ERVK-9 ADAM8

2.29e-04430416GO:0004175
GeneOntologyMolecularFunctionpeptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-25 ERVK-9 PRPF8 ADAM8

3.34e-04654417GO:0008233
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-8 ERVK-6

3.69e-0414412GO:0003964
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-8 ERVK-6

8.43e-0421412GO:0035613
GeneOntologyMolecularFunctionzinc ion binding

ERVK-8 ERVK-6 ERVK-19 ERVK-9 ADAM8 SF3A2 TARS1

2.05e-03891417GO:0008270
GeneOntologyMolecularFunctiontransition metal ion binding

ERVK-8 ERVK-6 CYP1B1 ERVK-19 ERVK-9 ADAM8 SF3A2 TARS1

2.54e-031189418GO:0046914
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-8 ERVK-6

2.62e-0337412GO:0016891
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-8 ERVK-6

2.76e-0338412GO:0034061
GeneOntologyMolecularFunctionglycosyltransferase activity

PGAP4 ST6GAL1 POGLUT1 WDFY3

2.82e-03288414GO:0016757
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-8 ERVK-6

4.02e-0346412GO:0016893
GeneOntologyMolecularFunctionprotein phosphatase inhibitor activity

STYXL1 SET

4.73e-0350412GO:0004864
GeneOntologyMolecularFunctionphosphatase inhibitor activity

STYXL1 SET

5.50e-0354412GO:0019212
GeneOntologyBiologicalProcesscell-cell fusion

ERVK-8 ERVK-6 ERVK-19 ERVK-9 ADAM8

4.15e-0785375GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

ERVK-8 ERVK-6 ERVK-19 ERVK-9 ADAM8

4.15e-0785375GO:0000768
GeneOntologyBiologicalProcesssyncytium formation

ERVK-8 ERVK-6 ERVK-19 ERVK-9 ADAM8

5.22e-0789375GO:0006949
GeneOntologyBiologicalProcessviral process

ERVK-8 ERVK-6 ERVK-19 ST6GAL1 ERVK-9 GRK2 TOP2B

1.60e-05464377GO:0016032
MousePhenoabsent subplate

WDFY3 TOP2B

2.49e-054292MP:0008443
DomainNAP

SET SETSIP

5.10e-0417372PF00956
DomainNAP_family

SET SETSIP

5.10e-0417372IPR002164
DomainGal_Oxidase_b-propeller

KLHL14 KLHDC10

2.06e-0334372IPR015916
Domain-

KLHL14 KLHDC10

4.07e-03483722.120.10.80
DomainKelch-typ_b-propeller

KLHL14 KLHDC10

5.31e-0355372IPR015915
DomainKelch

KLHL14 KLHDC10

5.89e-0358372SM00612
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-8 ERVK-6 ERVK-19 ERVK-9

8.17e-101241414557543
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-19 ERVK-9

3.03e-08641315063128
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-8 ERVK-6 ERVK-19 ERVK-25 ERVK-9

8.99e-089441521542922
Pubmed

Universal phosphatase-coupled glycosyltransferase assay.

ST6GAL1 POGLUT1

1.36e-06241221081508
Pubmed

PKD3 is the predominant protein kinase D isoform in mouse exocrine pancreas and promotes hormone-induced amylase secretion.

PRKD3 GANAB

1.36e-06241219028687
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

1.36e-0624129060628
Pubmed

Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.

ERVK-6 ERVK-19

1.36e-0624129460924
Pubmed

Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation.

SET PRPF8 SETSIP SF3A2 TOP2B

2.26e-0618041530110629
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-19

4.06e-06341210516026
Pubmed

Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.

ERVK-6 ERVK-9

4.06e-0634129971820
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-19

8.12e-0644127983737
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-19

1.35e-05541212629516
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-19

6.07e-051041212970426
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

NRM CYP1B1 PGAP4 ST6GAL1 POGLUT1 GANAB BTD HLA-F

6.84e-05120141835696571
Pubmed

Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line.

SET GRK2 PRPF8

1.13e-047941314729942
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-25 ERVK-9

2.05e-041841218664271
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

CYP1B1 PGAP4 SET ATP6V1H GANAB ECSIT PRPF8 TOP2B

2.39e-04144041830833792
Pubmed

Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation.

PRKD3 GANAB PRPF8 TARS1

2.41e-0425841421081666
Pubmed

Structure--function relationships in HIV-1 Nef.

ATP6V1H HLA-F

4.67e-042741211463741
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

SET GANAB GRK2 PRPF8

7.14e-0434441430333137
Pubmed

Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.

GANAB SF3A2 TARS1

7.72e-0415241316009940
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

GPCPD1 KLHL14 HECW2

7.87e-0415341310718198
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

SET GANAB ECSIT PRPF8 SETSIP NT5DC2 TARS1

8.65e-04133541729229926
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

PRKD3 POGLUT1 GANAB GRK2 TCEAL4 TARS1

1.10e-03100741634597346
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

SET PRPF8 SF3A2 TCEAL4 TARS1 TOP2B

1.14e-03101441632416067
InteractionHLA-B interactions

PGAP4 ST6GAL1 ATP6V1H WDFY3 TARS1 HLA-F

5.25e-06239386int:HLA-B
CoexpressionGSE19198_6H_VS_24H_IL21_TREATED_TCELL_UP

PRKD3 BTG3 CYP1B1 PLPP5 HLA-F

6.47e-06199355M7227
CoexpressionGSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_24H_DN

BTG3 WDFY3 ADAM8 NT5DC2

1.40e-04199354M9920
CoexpressionGSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_DN

BTG3 ATP6V1H TARS1 ACOX3

1.40e-04199354M7119
CoexpressionGSE29164_DAY3_VS_DAY7_UNTREATED_MELANOMA_DN

WDFY3 PLPP5 ADAM8 ACOX3

1.40e-04199354M8487
CoexpressionGSE17721_4_VS_24H_GARDIQUIMOD_BMDC_DN

GPCPD1 GRK2 ECSIT TARS1

1.40e-04199354M4147
CoexpressionGSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_UP

PRKD3 BTG3 TOP2B DENND2C

1.40e-04199354M9255
CoexpressionGSE6674_ANTI_IGM_VS_PL2_3_STIM_BCELL_DN

BTG3 PLPP5 PRPF8 TARS1

1.40e-04199354M6932
CoexpressionGSE14308_TH1_VS_INDUCED_TREG_DN

CYP1B1 GANAB ECSIT KLHDC10

1.43e-04200354M3379
CoexpressionGSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_DN

STYXL1 ATP6V1H TARS1 HLA-F

1.43e-04200354M4638
CoexpressionTSANG_PBMC_FLUVIRIN_PANDEMRIX_ADULT_CORR_WITH_CELL_FREQ_CD27HI_CD38HI_CD20_NEG_PLASMABLASTS_AND_CD38PLUS_OF_IGD_CD27PLUS_MEM_B_CELLS_7DY_POSITIVE

KLHL14 PLPP5 NT5DC2

1.55e-0478353M41196
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GAL1 PLPP5 DENND2C ANKRD53

1.38e-05182364a00abff41c12b71d5860c494b8c722d649fd5f36
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GAL1 PLPP5 DENND2C ANKRD53

1.38e-05182364626aabfd9ac662c1d189f7c4b660482914d9e669
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ST6GAL1 KLHL14 PLPP5 NT5DC2

1.63e-0519036484eb7761f537d270673909a71d4f122e826769d5
ToppCellCOVID-19_Severe-Plasmablast|COVID-19_Severe / disease group, cell group and cell class

ST6GAL1 KLHL14 PLPP5 NT5DC2

1.74e-051933648074bcede261b85f9ae03ee372bd6d4b40384537
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPCPD1 ST6GAL1 KLHL14 TOP2B

1.77e-0519436411709704079f24a730476572dc2f01e9d2226e2c
ToppCellPBMC-Severe-Lymphocyte-B|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ST6GAL1 KLHL14 PLPP5 NT5DC2

1.77e-05194364bd2c53fb064edfec76abe56a9ffaced0bda32ab0
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPCPD1 ST6GAL1 KLHL14 TOP2B

1.77e-051943643a1f95639d5f239f001bd67d4213e8938e7f299d
ToppCellCOVID_vent-Lymphocytic-Plasma_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

ST6GAL1 KLHL14 PLPP5 NT5DC2

1.92e-05198364e84c5f712e1dea548d0e2aba6625598f9671d3a0
ToppCellPND01-03-samps|World / Age Group, Lineage, Cell class and subclass

SEC14L3 HECW2 DENND2C

2.94e-041613631973b112d8d67aacc02751797d0148e7b53bfa66
ToppCellICU-NoSEP-Lymphocyte-B-Plasmablast|ICU-NoSEP / Disease, Lineage and Cell Type

KLHL14 PLPP5 NT5DC2

2.94e-041613638ca34d800551cb0f796293e6bfdcbf58509cc668
ToppCell10x5'-Lung-Lymphocytic_B-Naive_B_cells|Lung / Manually curated celltypes from each tissue

ST6GAL1 KLHL14 PLPP5

3.16e-041653631776e7db80d7cf6b449fa8635a111705a59231b4
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GAL1 PLPP5 ANKRD53

3.16e-041653639e2fa634f4749e35aa5dca43476477b5d362afd7
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRM ST6GAL1 KLHL14

3.22e-041663634b31d2755108b2815316411a38bfb11fd30ef98a
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 ADAM8 SLC23A1

3.28e-04167363a82e85caf79395baa48380786d9df32a86dfd1ce
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 ADAM8 SLC23A1

3.28e-04167363528493896aebe7d03d4b6ad2341b12927859e2e4
ToppCellfacs-Tongue-nan-3m-Epithelial-basal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM8 HECW2 DENND2C

3.34e-04168363ca0c4a819f9047fc40d224f7656fec60f6fa05d8
ToppCelldroplet-Fat-Gat-18m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRM ST6GAL1 KLHL14

3.45e-041703635185187ecf26b4c9eaa0c01ad52697ab8d075cc7
ToppCellnormal-na-Lymphocytic_B-B_plasma-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

KLHL14 NT5DC2 DENND2C

3.45e-04170363c5b87974dfddf9780051f7f5693eeeb0c606a3fe
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ST6GAL1 KLHL14 PLPP5

3.51e-04171363c3e3ea09c73050372314a89b282e36ba5f339d73
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

CYP1B1 WDFY3 NT5DC2

3.63e-04173363783b8fa08b9d8f597f251793eae164151662f1f9
ToppCell5'-Adult-Appendix-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GAL1 PLPP5 ANKRD53

3.63e-0417336368bcc0eee15df9cf3516c641709154301bd7b38f
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 PLPP5 SLC23A1

3.70e-041743633f4277763e312b46ebd4401ea4a2f5d4c850c768
ToppCelldroplet-Lung-nan-21m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 PLPP5 SLC23A1

3.70e-04174363fad66d1a8407574b6a835e0bdb824a53afa58650
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-plasma_cell-plasma_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ST6GAL1 PLPP5 SLC23A1

3.76e-0417536328b29f844fa46fe579ddc19039fb2d9dc5f48f3b
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-plasma_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ST6GAL1 PLPP5 SLC23A1

3.76e-04175363ac96ca9ca309b0d72a2f5af6a3b02c7f80755750
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_activate-7|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NRM KLHL14 NT5DC2

3.82e-04176363dde46f06f6fc3f7ba83be91a0ee6231790955e3e
ToppCellAdult-Immune-B_cell|Adult / Lineage, Cell type, age group and donor

ST6GAL1 KLHL14 PLPP5

3.82e-041763634aa00dcde907ad83d3aa4bb10439b7b5c4be1e5d
ToppCell(2)_Plasma_cells|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ST6GAL1 KLHL14 PLPP5

3.88e-04177363ed3c936bb69f9bc7291b4f6cde1d204078117c48
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-Plasma_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLHL14 PLPP5 NT5DC2

3.95e-04178363693f1135d9c5545945e80c7ba3d098afc0ccac29
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLHL14 PLPP5 NT5DC2

3.95e-041783636765c6970b1f2b719a20d2afd7471e1c262f3fc4
ToppCellNS-critical-LOC-Lymphoid-PC|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ST6GAL1 PLPP5 NT5DC2

4.01e-04179363c044478525b8e7eedecddb924c1b049331180cb2
ToppCell5'-Adult-Appendix-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GAL1 PLPP5 ANKRD53

4.01e-04179363ba7744b903abfc28b39a00472661f152e9ae39fd
ToppCellfacs-MAT-Fat-24m-Lymphocytic-B_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRM GRK2 KLHL14

4.08e-04180363711719219bcbafdd505790eda895e7a33f21bed2
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRM ST6GAL1 KLHL14

4.08e-04180363b51b10781082bc0305ba6a81e978729b329f7771
ToppCell356C-Lymphocytic-Plasma_cell|356C / Donor, Lineage, Cell class and subclass (all cells)

ST6GAL1 KLHL14 PLPP5

4.15e-04181363f1d88b83a13acd1c8e6b9ff8bd0acaff3650ceef
ToppCell356C-Lymphocytic-Plasma_cell-|356C / Donor, Lineage, Cell class and subclass (all cells)

ST6GAL1 KLHL14 PLPP5

4.15e-0418136370cd612706640d8ebf0e047582b1daa2c1121526
ToppCelldroplet-Mammary_Gland-nan-21m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPCPD1 NRM ST6GAL1

4.21e-0418236397f393549c7718a32af55b2377801bfebb10cc52
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B_plasma-Plasma_cells|GI_small-bowel / Manually curated celltypes from each tissue

ST6GAL1 PLPP5 DENND2C

4.28e-04183363ab5aaafcfd7b97330be6774be4c72611ca85257c
ToppCell10x5'-GI_small-bowel-Lymphocytic_B-Naive_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

ST6GAL1 KLHL14 PLPP5

4.28e-04183363be294d22b91dbcf1e8d22e6a31c39b5caaad4751
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B_plasma|GI_small-bowel / Manually curated celltypes from each tissue

ST6GAL1 PLPP5 DENND2C

4.28e-04183363193bfb787c1b36c8fabf4b00fafb5b398de6b999
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-B_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRM ST6GAL1 KLHL14

4.35e-04184363eb41dce59eb0384c1671fbc76eb15daab2c8c49a
ToppCell10x5'-Liver-Lymphocytic_B_plasma-Plasma_cells|Liver / Manually curated celltypes from each tissue

ST6GAL1 KLHL14 PLPP5

4.35e-041843636f70d8f8ab8362d51f8a58735d42223e06566397
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 KLHL14 TOP2B

4.35e-04184363b12fb85a064f715a4f0ada1df8e422c359b573cf
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-B_cell-B_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRM ST6GAL1 KLHL14

4.35e-04184363991500a874c5dd0d9111399520071da67bc6ac3d
ToppCellfacs-Marrow-T-cells-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 KLHL14 TOP2B

4.42e-04185363e1fd0a807def8c2127194108b1a30c6de7024292
ToppCellcritical-Myeloid-pDC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ST6GAL1 PLPP5 NT5DC2

4.42e-041853634a5d1d0a757f1f4fdb911be96ed90b52182c25f0
ToppCellBL-critical-LOC-Lymphoid-B_cell|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PRKD3 ST6GAL1 KLHL14

4.49e-0418636327d4c38b180e4ce2bf3e7c4ad3db3a2ffca05ca8
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgA_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

KLHL14 NT5DC2 DENND2C

4.49e-04186363e2c050ba02e1f84f0b7258dc92e7ff6ab349ff67
ToppCellmild-Lymphocytic-Plasmablast|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KLHL14 PLPP5 NT5DC2

4.49e-04186363060510c21b1e0889b7a6eeb15821b9e2f03a0f99
ToppCellB_cells-Plasma_cells_and_plasmablasts|World / Immune cells in Kidney/Urine in Lupus Nephritis

PLPP5 NT5DC2 DENND2C

4.56e-041873639325cadd5f2c667d526696899e7aa36a98226d4b
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-B_lymphocytic-naive_B_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ST6GAL1 KLHL14 PLPP5

4.56e-04187363160e5f338537d90d50f863a1be801b1071ac7da7
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLHL14 PLPP5 NT5DC2

4.56e-04187363d2296f2722a24b289fed7e6cfdc2105608437c3e
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLHL14 PLPP5 NT5DC2

4.56e-0418736306a0f0a27569af89f86ed8cddb608454a3d40cc5
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells|lymph-node_spleen / Manually curated celltypes from each tissue

KLHL14 PLPP5 NT5DC2

4.63e-04188363c7b1807c96f87fbcd37739a159cf00f9a1ff5d71
ToppCell3'_v3-bone_marrow-Lymphocytic_B_plasma-Plasmablasts|bone_marrow / Manually curated celltypes from each tissue

KLHL14 PLPP5 NT5DC2

4.63e-041883634caae2acd9ec0eb79b7476a1e59f30f39afddcda
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ST6GAL1 KLHL14 PLPP5

4.63e-04188363d8decd9b5967873ca8320c2f9f07365f163c777f
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

KLHL14 PLPP5 NT5DC2

4.63e-04188363ecba5d06cbf3254448255a2aeefffe711f43310e
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

KLHL14 PLPP5 NT5DC2

4.63e-041883638cf135da4d1d2500755d2809d60b41509af9fa8b
ToppCellSevere_COVID-19-B_cell|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

ST6GAL1 KLHL14 NT5DC2

4.70e-0418936359ce8f15f413557d2059ee6b53ba5957b864cb8e
ToppCell356C-Lymphocytic-Plasma_cell-|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KLHL14 PLPP5 NT5DC2

4.70e-04189363d1bd3b5ac32459929e556fb3a4fe8e1e15f6e658
ToppCellmild-Lymphocytic-Plasmablast|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KLHL14 PLPP5 NT5DC2

4.70e-04189363db2097e6e165004d47ed504e115083a4e4f4b147
ToppCell3'_v3-bone_marrow-Lymphocytic_B_plasma|bone_marrow / Manually curated celltypes from each tissue

KLHL14 PLPP5 NT5DC2

4.70e-04189363dceb011216deb4ffd830144a53c635c05dff5ec5
ToppCell356C-Lymphocytic-Plasma_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KLHL14 PLPP5 NT5DC2

4.70e-041893630994aba7a44577a8943af237c9c3575502d0584c
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ST6GAL1 KLHL14 PLPP5

4.78e-04190363a7498fe55b7810c482291db782dc5282675d246a
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-lymphocytic-B_lymphocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ST6GAL1 KLHL14 PLPP5

4.78e-04190363a21d0c574abf21e7cb865a21a48f29c92d055fbe
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ST6GAL1 KLHL14 PLPP5

4.78e-0419036360bb6aaea9691d07295f61c14d1650f5041a0f9c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLHL14 PLPP5 NT5DC2

4.78e-04190363f85cdd79eefd699ada7a91bf4997cc730a9b9846
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-B_lymphocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ST6GAL1 KLHL14 PLPP5

4.85e-041913633fc16e986aff5e0cd4f831e25e78a5b30beba7a8
ToppCellCOVID-19_Moderate-Plasmablast|World / disease group, cell group and cell class

KLHL14 PLPP5 NT5DC2

4.85e-04191363bb28703020c5296b65527094d2e5924348275e58
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLHL14 PLPP5 NT5DC2

4.85e-04191363208cd307826b5af89f8f10c0c915f90f80a25c6c
ToppCellPBMC-Convalescent-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KLHL14 PLPP5 NT5DC2

4.85e-04191363dd1d38a531a272a746c16807688013d29cab823a
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-B_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRM ST6GAL1 KLHL14

4.85e-041913636729b71fb674aea770a4a3167ccfc07acbf9f302
ToppCellsevere-Lymphocytic-Plasmablast|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KLHL14 PLPP5 NT5DC2

4.85e-0419136373660d762c9d451980c21adc426db6670bcaf37f
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-B_cell-B_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRM ST6GAL1 KLHL14

4.85e-04191363f9fed8dbc4e4e34e59d8c4154e4e3fb320b12257
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLHL14 PLPP5 NT5DC2

4.85e-04191363fca19f2719806f3dc2dd2add7252ab1198548f4d
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

WDFY3 GRK2 ADAM8

4.85e-04191363d4f77c73311d1149466bbfe4adbd6a301946ec90
ToppCellremission-Plasmablast|remission / disease stage, cell group and cell class

KLHL14 PLPP5 NT5DC2

4.92e-041923634bcf22061905177ad8625b87be2fbca9bff03ec6
ToppCellCOVID-19_Severe-Lymphoid_P|COVID-19_Severe / Disease group, lineage and cell class

ST6GAL1 KLHL14 NT5DC2

4.92e-041923633d0240491296757b3125f6e861bbaca06bbc5068
ToppCell10x5'v1-week_17-19-Lymphocytic_B-B_lineage-naive_B_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ST6GAL1 KLHL14 PLPP5

4.92e-041923635d6569b0f879729aa89d4498c9c886ac9050be13
ToppCell10x5'-bone_marrow-Lymphocytic_B-Naive_B_cells|bone_marrow / Manually curated celltypes from each tissue

ST6GAL1 KLHL14 PLPP5

4.92e-04192363fa99243ff028498c6a67d207a93e02c48e69cd42
ToppCellCOVID-19_Severe-Lymphoid_P-Plasmablast|COVID-19_Severe / Disease group, lineage and cell class

ST6GAL1 KLHL14 NT5DC2

4.92e-0419236390af8dad4e6f80b5ecd62027deeb2e4cea6b24bb
ToppCellCOVID-19_Moderate-Plasmablast|COVID-19_Moderate / disease group, cell group and cell class

KLHL14 PLPP5 NT5DC2

4.92e-0419236325c6c7a244190f82c7feab874bdec12490b7de4d
ToppCellCOVID-19_Severe-Plasmablast|World / disease group, cell group and cell class

KLHL14 PLPP5 NT5DC2

4.92e-04192363a333053fe2bd206c32790916bfc5fce904ab7f57
ToppCellfacs-Trachea-nan-3m-Epithelial-mucus_secreting_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL14 SLC23A1 DUOXA2

5.00e-041933633038ed3e53d3367136fac5c9773cd5b7414f49d3
ToppCellfacs-Trachea-3m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLHL14 SLC23A1 DUOXA2

5.00e-04193363c5925b3b5d19098e3987789d68a493d7fd548ac9
ToppCellPBMC-Convalescent-Lymphocyte-B-Plasmablast-Plasmablast-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

KLHL14 PLPP5 NT5DC2

5.00e-04193363902dea0bf6c2997d8b877ae01113460e511a364a
ToppCellPBMC-Convalescent-Lymphocyte-B-Plasmablast|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KLHL14 PLPP5 NT5DC2

5.00e-04193363239f2ac64f63d4d65997ba83b932a1fab1909efb
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-B_lymphocytic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ST6GAL1 KLHL14 PLPP5

5.00e-04193363ddc06227f2580774d9f34729dff912d6a9155f9c
ToppCellPBMC-Convalescent-Lymphocyte-B-Plasmablast-Plasmablast|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KLHL14 PLPP5 NT5DC2

5.00e-041933632790b245d6052063c207087b91fb9375a0e8055d
ToppCellPBMC-Convalescent-Lymphocyte-B-Plasmablast-Plasmablast|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

KLHL14 PLPP5 NT5DC2

5.00e-0419336394daa8a5d23558998fe3bff585344e22ce679f2d
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-B_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRM ST6GAL1 KLHL14

5.00e-04193363a808eb426b4ce9ddf7d6556b083abd9232a218b1
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ST6GAL1 KLHL14 NT5DC2

5.00e-04193363227d82059a9f99937e0188ff57f2d0e485ebfe69
ToppCellPBMC-Convalescent-Lymphocyte-B-Plasmablast|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

KLHL14 PLPP5 NT5DC2

5.00e-0419336333dad901e0597f0057edc2bfbd64fd81f298b94e
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ST6GAL1 KLHL14 NT5DC2

5.00e-0419336338bb14df7f05c29565a1c7f175fafe636e543bf8
ToppCellfacs-Trachea-3m-Epithelial-glandular_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLHL14 SLC23A1 DUOXA2

5.00e-041933636905de261d90dfe3dd2c2cf5b2e26afb2bcc3d5b
ToppCellfacs-Trachea-3m-Epithelial-glandular_epithelial-lung_secretory_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLHL14 SLC23A1 DUOXA2

5.00e-04193363f73630725f093c646bdaf178c39505c04a16e2c6
ToppCellremission-Plasmablast|World / disease stage, cell group and cell class

KLHL14 PLPP5 NT5DC2

5.00e-04193363d62617c72863642f2222f7ed28bc6b90ee09b4e0
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-B_cell-B_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRM ST6GAL1 KLHL14

5.00e-04193363e1d0b2d2d6b65d32922e22d092848ac4200669d5
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECSIT PLPP5 NT5DC2

5.00e-04193363f92bbe70e6c725bfb8c08bfc2a94e375528151a3
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ST6GAL1 KLHL14 NT5DC2

5.00e-04193363ce3873ece35fd2155ea235cb3c8bcd235cc0ebde
ComputationalNeighborhood of EIF3S2

SET GANAB PRPF8 SF3A2 TARS1

2.67e-04246265MORF_EIF3S2
ComputationalNeighborhood of BUB3

SET GANAB PRPF8 SF3A2 TARS1

4.62e-04277265MORF_BUB3
ComputationalNeighborhood of GNB1

SET GANAB PRPF8 SF3A2 TARS1

7.17e-04305265MORF_GNB1
ComputationalSpliceosome.

PRPF8 SF3A2

7.48e-0417262MODULE_388
DiseaseHepatitis, Toxic

GANAB ADAM8 BTD ACOX3

1.30e-03404354C0019193
DiseaseChemically-Induced Liver Toxicity

GANAB ADAM8 BTD ACOX3

1.30e-03404354C4279912
DiseaseDrug-Induced Liver Disease

GANAB ADAM8 BTD ACOX3

1.30e-03404354C0860207
DiseaseDrug-Induced Acute Liver Injury

GANAB ADAM8 BTD ACOX3

1.30e-03404354C3658290
DiseaseChemical and Drug Induced Liver Injury

GANAB ADAM8 BTD ACOX3

1.30e-03404354C4277682
DiseaseHepatitis, Drug-Induced

GANAB ADAM8 BTD ACOX3

1.30e-03404354C1262760
DiseaseIGA glomerulonephritis

SEC14L3 ST6GAL1

2.17e-0358352EFO_0004194
Diseaserheumatoid arthritis, COVID-19

SEC14L3 HLA-F

2.63e-0364352EFO_0000685, MONDO_0100096
DiseaseDermatitis, Allergic Contact

ST6GAL1 GRK2

2.88e-0367352C0162820
DiseaseCardiac Hypertrophy

CYP1B1 GRK2

4.28e-0382352C1383860
DiseaseCardiomegaly

CYP1B1 GRK2

4.28e-0382352C0018800
Diseasepsoriatic arthritis

SEC14L3 HLA-F

4.80e-0387352EFO_0003778

Protein segments in the cluster

PeptideGeneStartEntry
YVPFPPLIRAVTWMD

ERVK-19

106

O71037
YVPFPPLIRAVTWMD

ERVK-8

106

Q902F8
YVPFPPLIRAVTWMD

ERVK-9

106

Q9UKH3
VLEYPMQQWRLLPYL

ACOX3

346

O15254
MEQYEVVLPWRLPGP

ADAM8

26

P78325
LDWQMVFLQKYPPPL

GRK2

456

P25098
MEPREPWVEQEGPQY

HLA-F

66

P30511
PFEVLLRMLYPRVWP

ANKRD53

451

Q8N9V6
IVWRIEPGPYFMEPE

HECW2

121

Q9P2P5
VRDYPQVPKWMEPAI

POGLUT1

131

Q8NBL1
FQWVKLPATMPEPVY

KLHDC10

351

Q6PID8
IQNAAFMYPPNPWRE

PRKD3

786

O94806
ALALQLVMRYWEPIP

NRM

106

Q8IXM6
LQHYINPEPMRILEW

PGAP4

251

Q9BRR3
MTLWNGVLPFYPQPR

DUOXA2

1

Q1HG44
LIYDRIYDWMPEQPN

GPCPD1

606

Q9NPB8
RYDPRFNSWIQLPPM

KLHL14

396

Q9P2G3
YVPFPPLIRAVTWMD

ERVK-25

106

P61570
YVPFPPLIRAVTWMD

ERVK-6

106

Q69384
YPFLDFMPSPQVVRW

BTD

126

P43251
PYEDIPVQPLPMWRS

DENND2C

321

Q68D51
VDVMPWLQYFPNPVR

CYP1B1

241

Q16678
YVPFPPLIRAVTWMD

HERVK_113

106

Q902F9
ILDWQPPEVIQKYMP

SEC14L3

71

Q9UDX4
KLWFPRFMNVNPFPV

ECSIT

201

Q9BQ95
ELNPWPEYIYTRLEM

TARS1

46

P26639
TAWPYFLPMLNRQDP

ATP6V1H

121

Q9UI12
RVEPEWYIPIIPMVL

TOP2B

856

Q02880
GPFRWRDQMPPSYLL

FER1L5

1596

A0AVI2
EGIPVMRPLWVQYPQ

GANAB

721

Q14697
WPNPLQYYLVPDMDD

SETSIP

236

P0DME0
WPNPLQYYLVPDMDD

SET

226

Q01105
QPFYILKPQMPWELW

ST6GAL1

291

P15907
PPDRRWQYLLMAAEP

SF3A2

161

Q15428
VYQISELIFPPLPMW

BTG3

171

Q14201
MPMPWEQIRDVPVLY

PRPF8

106

Q6P2Q9
WMQRNLQDPFYPRGP

TCEAL4

181

Q96EI5
NDLMQYPVFPWILAD

WDFY3

2721

Q8IZQ1
IIWMPQELDAFQPYP

STYXL1

146

Q9Y6J8
IMAIAPWIRIPYPCQ

SLC23A1

296

Q9UHI7
PPFQRLIQPEEMWLY

PLPP5

31

Q8NEB5
LIQPEEMWLYRNPYV

PLPP5

36

Q8NEB5
YPRRTPLQHEAPLWM

NT5DC2

486

Q9H857