Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	1-phosphatidylinositol-4-phosphate 5-kinase activity	PIP4K2A PIP5K1A PIP5K1B PIP5K1C PIKFYVE	6.76e-08	9	284	5	GO:0016308
GeneOntologyMolecularFunction	1-phosphatidylinositol-3-phosphate 5-kinase activity	PIP5K1A PIP5K1B PIKFYVE	2.85e-06	3	284	3	GO:0000285
GeneOntologyMolecularFunction	1-phosphatidylinositol-5-kinase activity	PIP5K1A PIP5K1B PIKFYVE	2.85e-06	3	284	3	GO:0052810
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	RIPK1 MARK3 CLK4 OBSCN PAK6 BCR PTK2B GRK2 MAST4 CLK2 RPS6KL1 MAP3K8 PKMYT1 PIKFYVE EGFR MTOR PRKDC MAP2K2 EIF2AK2	2.33e-05	446	284	19	GO:0004674
GeneOntologyMolecularFunction	ATP-dependent activity	UBA5 ABCC4 SETX MYO1D MYO1E ABCA13 ZGRF1 PSMC3 SRCAP ABCA9 DHX8 IQCA1L KIF28P DYNC1H1 RAD51 DDX60 KATNA1 FIGN NLRP3 DNAH1 EIF4A1 DNAH17 POLQ	2.52e-05	614	284	23	GO:0140657
GeneOntologyMolecularFunction	phosphatidylinositol kinase activity	PIP4K2A PIP5K1A PIP5K1B PIP5K1C PIKFYVE	2.89e-05	26	284	5	GO:0052742
GeneOntologyMolecularFunction	protein serine kinase activity	RIPK1 MARK3 CLK4 OBSCN PAK6 BCR MAST4 CLK2 RPS6KL1 MAP3K8 PKMYT1 PIKFYVE MTOR PRKDC MAP2K2 EIF2AK2	6.92e-05	363	284	16	GO:0106310
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	PCYT1A RIPK1 MARK3 CLK4 OBSCN CCND1 PAK6 BCR PTK2B PARP4 GRK2 MAST4 CLK2 PIP4K2A DKC1 PIP5K1A PIP5K1B RPS6KL1 POLA1 MAP3K8 PIP5K1C PKMYT1 PIKFYVE EGFR MTOR PRKDC POLQ MAP2K2 EIF2AK2	7.62e-05	938	284	29	GO:0016772
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	RIPK1 MARK3 CLK4 OBSCN CCND1 PAK6 BCR PTK2B GRK2 MAST4 CLK2 PIP4K2A PIP5K1A PIP5K1B RPS6KL1 MAP3K8 PIP5K1C PKMYT1 PIKFYVE EGFR MTOR PRKDC MAP2K2 EIF2AK2	8.33e-05	709	284	24	GO:0016773
GeneOntologyMolecularFunction	transcription termination site sequence-specific DNA binding	SETX XRN2	2.02e-04	2	284	2	GO:0001147
GeneOntologyMolecularFunction	[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity	HS3ST3B1 HS3ST3A1	2.02e-04	2	284	2	GO:0033872
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCC4 MYO1E ABCA13 PSMC3 SRCAP ABCA9 DHX8 IQCA1L KIF28P DYNC1H1 RAD51 DDX60 KATNA1 FIGN NLRP3 EIF4A1 POLQ	2.08e-04	441	284	17	GO:0016887
GeneOntologyMolecularFunction	microtubule severing ATPase activity	IQCA1L KATNA1 FIGN	2.24e-04	9	284	3	GO:0008568
GeneOntologyMolecularFunction	kinase activity	RIPK1 MARK3 CLK4 OBSCN CCND1 PAK6 BCR PTK2B GRK2 MAST4 CLK2 PIP4K2A PIP5K1A PIP5K1B RPS6KL1 MAP3K8 PIP5K1C PKMYT1 PIKFYVE EGFR MTOR PRKDC MAP2K2 EIF2AK2	2.55e-04	764	284	24	GO:0016301
GeneOntologyMolecularFunction	lipid kinase activity	PIP4K2A PIP5K1A PIP5K1B PIP5K1C PIKFYVE	2.77e-04	41	284	5	GO:0001727
GeneOntologyMolecularFunction	protein kinase activity	RIPK1 MARK3 CLK4 OBSCN CCND1 PAK6 BCR PTK2B GRK2 MAST4 CLK2 RPS6KL1 MAP3K8 PKMYT1 PIKFYVE EGFR MTOR PRKDC MAP2K2 EIF2AK2	3.98e-04	600	284	20	GO:0004672
GeneOntologyMolecularFunction	signaling adaptor activity	DLG5 RIPK1 SHANK1 BIN1 NLRP3 AKAP12 MAP2K2 CAPRIN1	5.24e-04	129	284	8	GO:0035591
GeneOntologyMolecularFunction	Krueppel-associated box domain binding	HDAC1 HDAC2	5.99e-04	3	284	2	GO:0035851
GeneOntologyMolecularFunction	heparan sulfate sulfotransferase activity	NDST4 HS3ST3B1 HS3ST3A1	1.14e-03	15	284	3	GO:0034483
GeneOntologyMolecularFunction	protein-containing complex destabilizing activity	IQCA1L KATNA1 FIGN	1.14e-03	15	284	3	GO:0140776
GeneOntologyMolecularFunction	L27 domain binding	LIN7C LIN7A	1.19e-03	4	284	2	GO:0097016
GeneOntologyBiologicalProcess	peptidyl-serine autophosphorylation	RIPK1 MARK3 PIKFYVE MAP2K2	4.03e-06	9	281	4	GO:0036289
GeneOntologyBiologicalProcess	fungiform papilla formation	CTNNB1 HDAC1 HDAC2	9.91e-06	4	281	3	GO:0061198
GeneOntologyBiologicalProcess	organelle assembly	ABCC4 SYNPO2 ODAD1 OBSCN KAT2A CFAP65 DNAJB13 PTK2B NTNG2 SYNE2 PIP4K2A HPS1 POC1B SCFD1 DYNC1H1 CFAP47 RPGRIP1 SYNE1 HPS3 DNAH1 WDR19 PIKFYVE RAB3GAP1 TIA1 MTOR CCNB2 DNAH17 TTC21B CFAP74 MYOM2 PRKDC SPAG17 CAPRIN1 HDAC2	1.47e-05	1138	281	34	GO:0070925
GeneOntologyBiologicalProcess	nucleus localization	SYNE2 DYNC1H1 BIN1 SYNE1 MTOR FHOD1	2.77e-05	44	281	6	GO:0051647
GeneOntologyBiologicalProcess	hair follicle placode formation	CTNNB1 HDAC1 HDAC2	4.85e-05	6	281	3	GO:0060789
GeneOntologyBiologicalProcess	fungiform papilla morphogenesis	CTNNB1 HDAC1 HDAC2	4.85e-05	6	281	3	GO:0061197
GeneOntologyCellularComponent	leading edge membrane	MYO1D ITGAV SYNE2 PIP5K1A TESC PLA2G4F GPER1 DOCK8 GRIA1 PIP5K1C EGFR	1.27e-04	210	279	11	GO:0031256
GeneOntologyCellularComponent	postsynaptic density	DLG5 LIN7C PAK6 BCR LIN7A PTK2B LRFN2 GRK2 AFDN PLCB4 SHANK1 GPER1 GRIA1 PIP5K1C ADAM22 CTNNB1 EPB41L1	1.29e-04	451	279	17	GO:0014069
Domain	PIP5K	PIP4K2A PIP5K1A PIP5K1B PIP5K1C PIKFYVE	3.87e-08	8	279	5	PF01504
Domain	PIPK	PIP4K2A PIP5K1A PIP5K1B PIP5K1C PIKFYVE	3.87e-08	8	279	5	PS51455
Domain	-	PIP4K2A PIP5K1A PIP5K1B PIP5K1C PIKFYVE	3.87e-08	8	279	5	3.30.810.10
Domain	PIPKc	PIP4K2A PIP5K1A PIP5K1B PIP5K1C PIKFYVE	3.87e-08	8	279	5	SM00330
Domain	-	PIP4K2A PIP5K1A PIP5K1B PIP5K1C PIKFYVE	3.87e-08	8	279	5	3.30.800.10
Domain	PInositol-4-P-5-kinase_N	PIP4K2A PIP5K1A PIP5K1B PIP5K1C PIKFYVE	3.87e-08	8	279	5	IPR027484
Domain	PInositol-4-P-5-kinase_C	PIP4K2A PIP5K1A PIP5K1B PIP5K1C PIKFYVE	3.87e-08	8	279	5	IPR027483
Domain	PInositol-4-P-5-kinase_core	PIP4K2A PIP5K1A PIP5K1B PIP5K1C PIKFYVE	3.87e-08	8	279	5	IPR002498
Domain	PInositol-4-P-5-kinase	PIP4K2A PIP5K1A PIP5K1B PIP5K1C	1.65e-06	7	279	4	IPR023610
Domain	PDZ	DLG5 SYNPO2 LIN7C LIN7A MAST4 AFDN SIPA1L2 SHANK1 ARHGAP23 RGS12 SNTB1	8.97e-06	141	279	11	PF00595
Domain	PDZ	DLG5 SYNPO2 LIN7C LIN7A MAST4 AFDN SIPA1L2 SHANK1 ARHGAP23 RGS12 SNTB1	1.42e-05	148	279	11	SM00228
Domain	ARM-type_fold	USP34 RSPH14 CAND1 TRIP12 LYST UNC79 DOCK1 DOCK8 MROH2A NBEA IPO4 ECPAS MTOR PKP3 FHOD1 PRKDC CTNNB1	1.47e-05	339	279	17	IPR016024
Domain	-	DLG5 SYNPO2 LIN7C LIN7A MAST4 AFDN SIPA1L2 SHANK1 ARHGAP23 RGS12 SNTB1	1.61e-05	150	279	11	2.30.42.10
Domain	PDZ	DLG5 SYNPO2 LIN7C LIN7A MAST4 AFDN SIPA1L2 SHANK1 ARHGAP23 RGS12 SNTB1	1.72e-05	151	279	11	PS50106
Domain	PDZ	DLG5 SYNPO2 LIN7C LIN7A MAST4 AFDN SIPA1L2 SHANK1 ARHGAP23 RGS12 SNTB1	1.83e-05	152	279	11	IPR001478
Domain	ARM-like	RSPH14 CAND1 SETX TRIP12 DOCK8 MROH2A NBEA IPO4 ECPAS MTOR PKP3 FHOD1 PRKDC CTNNB1	5.87e-05	270	279	14	IPR011989
Domain	-	DLG5 ABCC4 SETX MYO1E ABCA13 ZGRF1 NDST4 PSMC3 SRCAP ABCA9 DHX8 RHOBTB2 HS3ST3B1 HS3ST3A1 DYNC1H1 RAD51 WSCD1 DDX60 KATNA1 FIGN DNAH1 GTPBP2 GTPBP8 EIF4A1 POLQ	1.48e-04	746	279	25	3.40.50.300
Domain	C2	HECW1 BCR PLCB4 PLA2G4F RPGRIP1 NEDD4L ESYT1 CADPS PLCE1	1.57e-04	131	279	9	PF00168
Domain	P-loop_NTPase	DLG5 ABCC4 SETX MYO1D MYO1E ABCA13 ZGRF1 NDST4 PSMC3 SRCAP ABCA9 DHX8 RHOBTB2 HS3ST3B1 HS3ST3A1 DYNC1H1 RAD51 WSCD1 DDX60 KATNA1 FIGN NLRP3 DNAH1 GTPBP2 GTPBP8 EIF4A1 POLQ	1.84e-04	848	279	27	IPR027417
Domain	C2	HECW1 BCR PLCB4 PLA2G4F RPGRIP1 NEDD4L ESYT1 CADPS PLCE1	2.20e-04	137	279	9	SM00239
Domain	Otx_TF	OTX1 OTX2	2.22e-04	2	279	2	IPR003025
Domain	SPIN-2	SPIN2A SPIN2B	2.22e-04	2	279	2	IPR029564
Domain	C2	HECW1 BCR PLCB4 PLA2G4F RPGRIP1 NEDD4L ESYT1 CADPS PLCE1	2.88e-04	142	279	9	PS50004
Domain	HEAT_REPEAT	CAND1 MROH2A IPO4 ECPAS MTOR PRKDC	6.20e-04	70	279	6	PS50077
Domain	Otx_TF_C	OTX1 OTX2	6.60e-04	3	279	2	IPR013851
Domain	TF_Otx	OTX1 OTX2	6.60e-04	3	279	2	PF03529
Domain	PH_dom-like	CYTH3 OBSCN MCF2 BCR LYST PTK2B GRK2 PLCB4 ARHGAP23 NBEA RGS12 GTF2H1 CADPS SNTB1 EPB41L1 PLCE1	7.14e-04	426	279	16	IPR011993
Domain	C2_dom	HECW1 BCR PLCB4 PLA2G4F RPGRIP1 NEDD4L ESYT1 CADPS PLCE1	8.21e-04	164	279	9	IPR000008
Pathway	WP_PHOSPHATIDYL_INOSITOL_PHOSPHATE_PATHWAY	PIP4K2A PIP5K1A PIP5K1B PLCB4 PIP5K1C PIKFYVE PLCE1	5.62e-06	46	215	7	M48317
Pathway	WP_PHOSPHOINOSITIDES_METABOLISM	PIP4K2A PIP5K1A PIP5K1B PLCB4 PIP5K1C PIKFYVE PLCE1	8.68e-06	49	215	7	M40046
Pathway	KEGG_INOSITOL_PHOSPHATE_METABOLISM	PIP4K2A PIP5K1A PIP5K1B PLCB4 PIP5K1C PIKFYVE PLCE1	1.68e-05	54	215	7	M3896
Pathway	KEGG_MEDICUS_REFERENCE_NLRP3_INFLAMMASOME_SIGNALING_PATHWAY	IL18 CASP1 NLRP3	6.76e-05	6	215	3	M47624
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	CPA4 PCYT1A CAND1 SETX LIN7C CENPB ERAP1 PSMC3 ITGAV TRIP12 SERPINB6 FBXO3 HPRT1 SYNE2 PIP5K1A PLCB4 DYNC1H1 ATPAF1 NEDD4L ESYT1 L1CAM FARSB UFL1 AKAP12 SART1 EGFR PKP3 EIF4A1 UGGT2 NAA30 HAGH PRKDC CTNNB1 EIF2AK2 CAPRIN1 HDAC1	1.94e-10	1297	285	36	33545068
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CAND1 MYO1D MYO1E MARK3 PSMC3 PSMD3 BCR MRPS22 PTK2B STXBP1 GRK2 PNPLA6 SACS PIP4K2A AFDN SIPA1L2 IMMT DYNC1H1 SDHA SHANK1 ADCY4 BIN1 NEDD4L ARHGAP23 DOCK8 SYNE1 L1CAM FARSB GRIA1 NBEA SLC1A3 ADAM22 CADPS KIAA1217 TMPO CTNNB1 CAPRIN1 EPB41L1	2.04e-10	1431	285	38	37142655
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	DLG5 MYO1D MYO1E MARK3 PSMD3 TRIP12 MRPS22 DHX8 PNPLA6 ASCC2 IMMT DYNC1H1 SDHA XRN2 ESYT1 DDX60 FARSB IPO4 APOBEC3B SART1 HARS2 GTF2H1 EGFR PKP3 KIAA1217 FHOD1 UTP4 EIF4A1 TMPO PRKDC NUP93 CTNNB1 EIF2AK2 CAPRIN1 HDAC1	3.27e-10	1257	285	35	36526897
Pubmed	Localization of mRNAs for phosphatidylinositol phosphate kinases in the mouse brain during development.	PIP4K2A PIP5K1A PIP5K1B PIP5K1C PIKFYVE	7.39e-10	7	285	5	15018809
Pubmed	Btk-dependent regulation of phosphoinositide synthesis.	PIP4K2A PIP5K1A PIP5K1B PIP5K1C PIKFYVE	1.96e-09	8	285	5	15046600
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	CPA4 IL18 CAND1 SETX PSMC3 PSMD3 SRCAP TRIP12 SERPINB6 PNPLA6 PIP4K2A DKC1 AFDN SCFD1 IMMT DYNC1H1 MPO XRN2 ARHGAP23 SPTLC2 POLA1 ESYT1 RPP30 FARSB IPO4 SART1 RAB3GAP1 GTF2H1 FHOD1 UTP4 EIF4A1 PRKDC NUP93 EIF2AK2 CAPRIN1	2.23e-09	1353	285	35	29467282
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	UBA5 CAND1 PSMC3 PSMD3 PSMD8 DKC1 SCFD1 IMMT DYNC1H1 XRN2 POLA1 ESYT1 UFL1 IPO4 ECPAS MTOR TMPO PRKDC NUP93 CTNNB1 MAP2K2 HDAC1 HDAC2	3.96e-09	638	285	23	33239621
Pubmed	Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family.	PIP4K2A PIP5K1A PIP5K1B PIP5K1C	4.42e-09	4	285	4	9535851
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	USP34 CAND1 MYO1D PSMC3 PSMD3 PSMD8 BCR MRPS22 LIN7A FBXO3 HPRT1 ASCC2 DKC1 PIP5K1A SCFD1 USP15 IMMT SDHA ANAPC4 XRN2 RPP30 FARSB IPO4 NXN BTBD7 EIF4A1 TMPO INTS9 PRKDC NUP93 EIF2AK2 CAPRIN1 HDAC1 HDAC2	5.68e-09	1335	285	34	29229926
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP34 MYO1D PSMC3 TRIP12 DHX8 SYNE2 AFDN IMMT DYNC1H1 SDHA USP47 XRN2 POLA1 IPO4 ECPAS SART1 MTOR UTP4 EIF4A1 PRKDC NUP93 CAPRIN1 HDAC2	6.12e-09	653	285	23	22586326
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	DLG5 MARK3 FASTKD5 PSMD8 MRPS22 ZNF512B DNAJB13 PNPLA6 SACS SYNE2 ASCC2 PIP5K1A SCFD1 SIPA1L2 IMMT ATPAF1 SDHA LYRM4 ESYT1 SYNE1 RPP30 UFL1 IPO4 AKAP12 SLC5A3 PKMYT1 WDR19 RAB3GAP1 EGFR UTP4 TMPO UGGT2 CTNNB1 CAPRIN1 SNTB1 EPB41L1	7.23e-09	1487	285	36	33957083
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CAND1 HECW1 CYTH3 BCR SYNE2 AFDN UNC79 DYNC1H1 SHANK1 BIN1 NEDD4L SYNE1 FARSB GRIA1 SPATA20 NBEA IPO4 SLC1A3 ADAM22 AKAP12 SART1 MTOR KIAA1217 EIF4A1 CTNNB1 CAPRIN1 EPB41L1 HDAC2	8.69e-09	963	285	28	28671696
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	PCYT1A PSMD3 FASTKD5 DHX8 ASCC2 SYPL1 PIP5K1A AFDN IMMT DYNC1H1 SDHA SPTLC2 ESYT1 IPO4 ECPAS RAB3GAP1 UTP4 TMPO NUP93 HDAC1 HDAC2	9.76e-09	560	285	21	35241646
Pubmed	Defining the membrane proteome of NK cells.	ABCC4 CAND1 ERAP1 PSMC3 PSMD3 BCR PARP4 GRK2 PNPLA6 PIGA IMMT DYNC1H1 XRN2 DPY19L1 DOCK8 ESYT1 FARSB IPO4 ECPAS PKMYT1 MTOR FHOD1 EIF4A1 TMPO ABHD13 PRKDC NUP93 EIF2AK2 CAPRIN1 LMBRD1 NCKAP1L	1.10e-08	1168	285	31	19946888
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	USP34 CAND1 LIN7C PSMC3 PSMD3 PSMD8 BCR MRPS22 LIN7A MDP1 FBXO3 PIP5K1A AFDN SIPA1L2 IMMT SDHA USP47 MPO SPTLC2 ESYT1 FARSB IPO4 ECPAS MTOR PKP3 PRKDC NUP93 SNTB1	1.11e-08	974	285	28	28675297
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	UBA5 CAND1 SETX PSMC3 PSMD3 TRIP12 DHX8 PARP4 DYNC1H1 DOCK1 XRN2 RBM45 DOCK8 SART1 PKP3 FHOD1 EIF4A1 TMPO PRKDC NUP93 MAP2K2	1.89e-08	582	285	21	20467437
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	CAND1 MYO1D PSMC3 PSMD3 FASTKD5 PSMD8 DHX8 HPRT1 DKC1 AFDN SCFD1 TDRD6 IMMT DYNC1H1 SDHA ADCY4 XRN2 POLA1 ESYT1 SYNE1 FARSB UFL1 IPO4 ECPAS SART1 MTOR UTP4 EIF4A1 TMPO PRKDC NUP93 EIF2AK2 CAPRIN1 HDAC1	2.80e-08	1425	285	34	30948266
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	MYO1E PSMC3 FASTKD5 PIP4K2A DKC1 AFDN TAF10 IMMT DYNC1H1 SDHA ESYT1 UFL1 IPO4 ECPAS NXN SART1 PKP3 TMPO PRKDC CTNNB1 MAP2K2 CAPRIN1 HDAC1	2.93e-08	711	285	23	33022573
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	DLG5 CAND1 LIN7C MYO1D MARK3 PSMC3 PSMD3 TRIP12 MRPS22 DHX8 ASCC2 USP15 IMMT DYNC1H1 SDHA RAD51 FARSB DNAH1 SART1 PKP3 UTP4 EIF4A1 TMPO PRKDC NUP93 CTNNB1 MAP2K2 EIF2AK2 CAPRIN1 HDAC1 HDAC2	4.85e-08	1247	285	31	27684187
Pubmed	Branches of the B cell antigen receptor pathway are directed by protein conduits Bam32 and Carma1.	PIP4K2A PIP5K1A PIP5K1B PIP5K1C	6.54e-08	6	285	4	14614850
Pubmed	Rac controls PIP5K localisation and PtdIns(4,5)P₂ synthesis, which modulates vinculin localisation and neurite dynamics.	PIP5K1A PIP5K1B PIP5K1C PIKFYVE	6.54e-08	6	285	4	20841379
Pubmed	HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.	USP34 CAND1 PSMC3 PSMD3 PSMD8 MRPS22 HPRT1 PIP5K1A LSM11 USP15 DYNC1H1 SDHA ESYT1 RPP30 FARSB IPO4 EIF4A1 PRKDC CTNNB1 HDAC2	6.75e-08	571	285	20	37167062
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	CAND1 LIN7C CENPB MARK3 PSMC3 PSMD3 KAT2A BCR TRIP12 LIN7A DHX8 FBXO3 DKC1 USP27X USP15 IMMT USP47 NEDD4L RBM45 POLA1 IPO4 NXN SART1 KLHL15 UGGT2 NUP93 ZMYM6	8.11e-08	1005	285	27	19615732
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CAND1 MYO1D PSMD3 SRCAP TRIP12 DHX8 ZNF512B SACS HPRT1 SYNE2 DKC1 AFDN IMMT DYNC1H1 XRN2 NEDD4L SYNE1 UFL1 SART1 PKP3 UTP4 EIF4A1 TMPO PRKDC NUP93 CTNNB1 HDAC2	1.18e-07	1024	285	27	24711643
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MYO1D PSMD3 PSMD8 KAT2A SRCAP TRIP12 LYST STXBP1 SACS SYNE2 PIP4K2A DKC1 SIPA1L2 IMMT RPGRIP1 PCDHGC4 PCDHGA5 SYNE1 GRIA1 REL SART1 STS EIF4A1 TMPO CFAP74 UGGT2 MYOM2 PRKDC POLQ SPAG17 DOP1A HDAC1 HDAC2	1.20e-07	1442	285	33	35575683
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	USP34 RIPK1 MARK3 CLK4 PSMD3 FASTKD5 BCR LYST PTK2B CLK2 PIP4K2A TAF10 USP27X ANAPC4 ARHGAP23 DPY19L1 GTF2H1 EGFR RTL1 CCNB2 CTNNB1 MAP2K2 SNTB1 HDAC1 HDAC2	1.66e-07	910	285	25	36736316
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	PSMD3 ITGAV IQCA1L SPIN2A DKC1 SIPA1L2 MPO ESYT1 ECM2 MROH2A COX11 DNAH1 GTPBP2 CADPS TMPO POLQ EIF2AK2 HDAC2	1.85e-07	496	285	18	31343991
Pubmed	Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.	PSMC3 PSMD3 BCR MRPS22 DYNC1H1 RPP30 IPO4 EIF4A1 TMPO PRKDC HDAC1 HDAC2	2.02e-07	211	285	12	17314511
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	FNBP1 USP34 DLG5 ERAP1 USP15 WSCD1 SPTLC2 PIP5K1C CCDC144A	2.22e-07	105	285	9	9628581
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	DLG5 PSMC3 PSMD3 TRIP12 USP15 DYNC1H1 USP47 ESYT1 RPP30 UFL1 HARS2 TMPO PRKDC CTNNB1 HDAC1 HDAC2	2.39e-07	399	285	16	37536630
Pubmed	DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.	CAND1 PSMC3 PSMD3 IMMT DYNC1H1 SDHA XRN2 NXN EIF4A1 TMPO PRKDC	2.41e-07	175	285	11	25756610
Pubmed	Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain.	PIP4K2A PIP5K1A PIP5K1B PIP5K1C	3.01e-07	8	285	4	20622009
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	USP34 PCYT1A CAND1 ZNF234 MYO1E CYTH3 HLCS TRIP12 ME3 CNOT8 ZNF512B CYRIA STXBP1 SACS AFDN IMMT DYNC1H1 SDHA USP47 SHANK1 BIN1 XRN2 SYNE1 NBEA ADAM22 WDR19 CADPS EIF4A1 PRKDC CAPRIN1	3.08e-07	1285	285	30	35914814
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	CAND1 PSMC3 FASTKD5 PSMD8 TRIP12 PNPLA6 SCFD1 IMMT DYNC1H1 SDHA SPTLC2 ESYT1 FARSB UFL1 IPO4 ECPAS RAB3GAP1 MTOR CCNB2 EIF4A1 TMPO UGGT2 PRKDC NUP93 CTNNB1	3.14e-07	942	285	25	31073040
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	USP34 CAND1 MYO1E CENPB MARK3 PSMC3 PSMD3 FASTKD5 CCND1 MRPS22 SYNE2 ASCC2 DKC1 SCFD1 DYNC1H1 SDHA XRN2 SPTLC2 ESYT1 DDX60 FARSB UFL1 IPO4 ECPAS RAB3GAP1 MTOR EIF4A1 TMPO PRKDC NUP93 CTNNB1 CAPRIN1	3.60e-07	1440	285	32	30833792
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	MARK3 ITGAV STXBP1 PIP5K1A SCFD1 SIPA1L2 SDHA NEDD4L ESYT1 UFL1 AKAP12 EGFR KIAA1217 CTNNB1 SNTB1 EPB41L1	4.89e-07	421	285	16	36976175
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	USP34 DLG5 SETX MYO1D ZGRF1 SRCAP BCR HPRT1 PIP4K2A TONSL SIPA1L2 XRN2 IPO4 PIKFYVE CCNB2 KIAA1217 UTP4 CTNNB1 ZMYM6	4.92e-07	588	285	19	38580884
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	CAND1 HLCS PSMC3 PSMD3 FASTKD5 TRIP12 MRPS22 CLK2 HPRT1 PIP4K2A DKC1 SCFD1 TAF10 DYNC1H1 SDHA XRN2 ESYT1 FARSB UFL1 IPO4 APOBEC3B UTP4 EIF4A1 TMPO PRKDC NUP93 MAP2K2 EIF2AK2 HDAC1 HDAC2	5.23e-07	1318	285	30	30463901
Pubmed	Survival and lung pathology of mouse models of Hermansky-Pudlak syndrome and Chediak-Higashi syndrome.	LYST HPS1 RABGGTA HPS3	5.39e-07	9	285	4	10193444
Pubmed	NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses.	IL18 CASP1 NLRP3	5.45e-07	3	285	3	20574004
Pubmed	Abnormal beta-catenin expression in oral cancer with no gene mutation: correlation with expression of cyclin D1 and epidermal growth factor receptor, Ki-67 labeling index, and clinicopathological features.	CCND1 EGFR CTNNB1	5.45e-07	3	285	3	15791567
Pubmed	Increased expression of NLRP3 inflammasome components and interleukin-18 in patients with bullous pemphigoid.	IL18 CASP1 NLRP3	5.45e-07	3	285	3	27174093
Pubmed	Lactobacillus casei ATCC 393 and it's metabolites alleviate dextran sulphate sodium-induced ulcerative colitis in mice through the NLRP3-(Caspase-1)/IL-1β pathway.	IL18 CASP1 NLRP3	5.45e-07	3	285	3	34755743
Pubmed	Phosphatidylinositol-4-phosphate 5-kinase isoforms exhibit acyl chain selectivity for both substrate and lipid activator.	PIP5K1A PIP5K1B PIP5K1C	5.45e-07	3	285	3	22942276
Pubmed	Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.	SYNE2 SYNE1 FHOD1	5.45e-07	3	285	3	33472039
Pubmed	Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42.	PIP5K1A PIP5K1B PIP5K1C	5.45e-07	3	285	3	14681219
Pubmed	PIP5KIβ selectively modulates apical endocytosis in polarized renal epithelial cells.	PIP5K1A PIP5K1B PIP5K1C	5.45e-07	3	285	3	23342003
Pubmed	The C-terminal cytoplasmic tail of hedgehog receptor Patched1 is a platform for E3 ubiquitin ligase complexes.	PSMC3 PSMD3 PSMD8 GRK2 PIP4K2A USP15 DYNC1H1 PIKFYVE	5.63e-07	86	285	8	26885983
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	CAND1 PTK2B STXBP1 SACS DYNC1H1 SHANK1 SYNE1 GRIA1 NBEA SLC1A3 ADAM22 MTOR EPB41L1	6.69e-07	281	285	13	28706196
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	PCYT1A CAND1 MYO1E SEC24A PSMC3 PSMD3 MRPS22 DHX8 SERPINB6 FBXO3 HPRT1 SYNE2 DKC1 IMMT DYNC1H1 SDHA NEDD4L POLA1 FARSB UFL1 SLC1A3 SART1 EGFR PKP3 FHOD1 EIF4A1 HAGH PRKDC EIF2AK2 CAPRIN1 HDAC2	7.51e-07	1415	285	31	28515276
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	DLG5 CAND1 SETX LIN7C MARK3 CLK4 KAT2A MRPS22 CNOT8 DHX8 GREB1L PNPLA6 ASCC2 AFDN LSM11 TAF10 IMMT SDHA ESYT1 SYNE1 RPP30 FARSB UFL1 IPO4 HARS2 GTF2H1 UTP4 EIF4A1 INTS9 EIF2AK2 EPB41L1 HDAC1	8.35e-07	1497	285	32	31527615
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DLG5 SETX MARK3 SEC24A PAK6 BCR TRIP12 LYST PTK2B MAST4 SYNE2 AFDN SIPA1L2 NEDD4L ESYT1 RGS12 VPS13D MTOR KIAA1217 NUP93 MAP2K2 EPB41L1 DOP1A	8.50e-07	861	285	23	36931259
Pubmed	Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis.	CAND1 ERAP1 OBSCN FASTKD5 MRPS22 SERPINB6 RAD51 XRN2 MAP2K2 HDAC2	8.50e-07	159	285	10	31332168
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	TRIP12 PARP4 DOCK1 DDX60 IPO4 ECPAS EGFR MTOR TMPO PRKDC CAPRIN1	1.01e-06	202	285	11	33005030
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	UBA5 DLG5 CAND1 LIN7C ERAP1 PSMD8 MRPS22 SYNE2 PIP5K1A AFDN SCFD1 IMMT XRN2 SPTLC2 ESYT1 RRM2B IPO4 ECPAS APOBEC3B AKAP12 PTGR1 MTOR EIF4A1 TMPO HAGH PRKDC NUP93 CTNNB1 MMUT HDAC1	1.11e-06	1367	285	30	32687490
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	CAND1 SEC24A PSMC3 HPRT1 AFDN SCFD1 USP15 ESYT1 NBEA IPO4 ECPAS AKAP12 RAB3GAP1 EIF4A1 TMPO PRKDC	1.14e-06	449	285	16	31732153
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	UBA5 ABCC4 CAND1 PSMD3 TRIP12 HPRT1 USP15 IMMT DYNC1H1 RABGGTA SDHA USP47 SPTLC2 ESYT1 IPO4 ECPAS AKAP12 FHOD1 EIF4A1 PRKDC NUP93 MAP2K2 HDAC2	1.18e-06	878	285	23	37223481
Pubmed	SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.	CAND1 PSMC3 HPRT1 DKC1 IMMT DYNC1H1 SDHA ESYT1 SYNE1 EIF4A1 TMPO PRKDC NUP93 EIF2AK2 CAPRIN1 HDAC1	1.69e-06	463	285	16	34901782
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	PSMC3 PSMD3 TRIP12 MRPS22 DHX8 STXBP1 HPRT1 SCFD1 DYNC1H1 XRN2 POLA1 RPP30 FARSB IPO4 RAB3GAP1 MTOR UTP4 EIF4A1 PRKDC EIF2AK2	1.79e-06	704	285	20	29955894
Pubmed	Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.	MYO1D PSMD3 SYNE2 DKC1 PRKDC CAPRIN1 HDAC1 HDAC2	1.93e-06	101	285	8	26949739
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	DLG5 RIPK1 MARK3 SEC24A HLCS PSMD3 AFDN IMMT DYNC1H1 SDHA DOCK1 ESYT1 FARSB ECPAS AKAP12 EGFR TMPO PRKDC EPB41L1 HDAC1	1.95e-06	708	285	20	39231216
Pubmed	An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury.	IL18 CASP1 NLRP3	2.16e-06	4	285	3	20962258
Pubmed	Holocarboxylase synthetase acts as a biotin-independent transcriptional repressor interacting with HDAC1, HDAC2 and HDAC7.	HLCS HDAC1 HDAC2	2.16e-06	4	285	3	24239178
Pubmed	HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination.	CTNNB1 HDAC1 HDAC2	2.16e-06	4	285	3	21423191
Pubmed	Effects of CD73 on human colorectal cancer cell growth in vivo and in vitro.	CCND1 EGFR CTNNB1	2.16e-06	4	285	3	26708311
Pubmed	Mechanism and Regulation of NLRP3 Inflammasome Activation.	IL18 CASP1 NLRP3	2.16e-06	4	285	3	27669650
Pubmed	Intra-amniotic inflammation induces preterm birth by activating the NLRP3 inflammasome†.	IL18 CASP1 NLRP3	2.16e-06	4	285	3	30590393
Pubmed	Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes.	PIP5K1A PIP5K1B PIP5K1C	2.16e-06	4	285	3	18188447
Pubmed	Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury.	IL18 CASP1 NLRP3	2.16e-06	4	285	3	23904166
Pubmed	Identification and characterization of a phosphoinositide phosphate kinase homolog.	PIP5K1A PIP5K1B PIP5K1C	2.16e-06	4	285	3	14701839
Pubmed	IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation.	IL18 CASP1 NLRP3	2.16e-06	4	285	3	20855874
Pubmed	The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18.	IL18 CASP1 NLRP3	2.16e-06	4	285	3	21106820
Pubmed	The alveolar epithelium determines susceptibility to lung fibrosis in Hermansky-Pudlak syndrome.	LYST HPS1 HPS3	2.16e-06	4	285	3	23043085
Pubmed	Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression.	MTOR HDAC1 HDAC2	2.16e-06	4	285	3	27048565
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	FNBP1 ABCC4 CENPB MRPS22 CYRIA PNPLA6 SYPL1 AFDN PLCB4 MYRF BIN1 SPTLC2 SYNE1 RRM2B RGS12 AKAP12 GTPBP8 EGFR FHOD1 EPB41L1	2.46e-06	719	285	20	35337019
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	MYO1D MYO1E BCR TRIP12 CNOT8 DHX8 PARP4 GRK2 PIP4K2A ASCC2 DKC1 PIP5K1A POLA1 DDX60 RPP30 AKAP12 SART1 UTP4 NAA30 CAPRIN1	2.73e-06	724	285	20	36232890
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	CYP4F8 MYO1D MARK3 PSMC3 PSMD3 PSMD8 PAK6 MRPS22 CNOT8 CLK2 HPRT1 TONSL PIP5K1B AFDN USP15 UNC79 DYNC1H1 RAD51 UFL1 IPO4 ECPAS NXN EIF4A1 NUP93 CTNNB1 POLQ EIF2AK2 CAPRIN1	2.91e-06	1284	285	28	17353931
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	MYO1E PSMD3 MRPS22 PTK2B KIF28P UNC79 SYNE1 ZFHX4 PKP3 TMPO MMUT HDAC1 HDAC2	2.93e-06	321	285	13	32098917
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	HECW1 PSMD3 BCR LIN7A SERPINB6 STXBP1 GRK2 HPRT1 AFDN SIPA1L2 USP15 SDHA SHANK1 BIN1 NEDD4L GRIA1 NBEA SLC1A3 ADAM22 RAB3GAP1 CADPS KIAA1217 CTNNB1 CAPRIN1 EPB41L1 HDAC2	2.97e-06	1139	285	26	36417873
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	USP34 CAND1 PSMD8 TRIP12 STXBP1 SYNE2 SCN10A DYNC1H1 COX11 IPO4 RGS12 OTX1 PRKDC	3.03e-06	322	285	13	26514267
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	CAND1 LIN7C MARK3 ITGAV STXBP1 PIP5K1A BIN1 ESYT1 PIP5K1C AKAP12 TMPO CTNNB1 SNTB1 EPB41L1	3.33e-06	377	285	14	38117590
Pubmed	Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients.	PSMD3 KAT2A ECPAS MTOR	4.14e-06	14	285	4	28878358
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	USP34 MRPS22 SCFD1 USP15 ANAPC4 RPP30 IPO4 TIA1 ZFHX4 INTS9 NUP93 CTNNB1	4.27e-06	282	285	12	23667531
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	PSMD3 TRIP12 SACS SYNE2 BIN1 XRN2 NEDD4L ESYT1 NBEA IPO4 ECPAS CADPS TMPO CTNNB1 EIF2AK2 EPB41L1	4.28e-06	498	285	16	36634849
Pubmed	Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.	CAND1 KAT2A SRCAP BCR TRIP12 TAF10 DOCK1 UBE2NL ARHGAP23 ECPAS SART1 GTF2H1 EIF4A1 MAP2K2	4.91e-06	390	285	14	17643375
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	TRAF3IP2 MYO1E CENPB PSMC3 PSMD8 ITGAV BCR HPRT1 AFDN USP15 IMMT DYNC1H1 RPGRIP1 XRN2 ESYT1 IPO4 NXN AKAP12 WDR19 SART1 GTF2H1 MTOR TTC21B UGGT2 CTNNB1 CCDC144A HDAC1 HDAC2	4.96e-06	1321	285	28	27173435
Pubmed	The DNA Sensor AIM2 Maintains Intestinal Homeostasis via Regulation of Epithelial Antimicrobial Host Defense.	IL18 CASP1 NLRP3	5.38e-06	5	285	3	26655906
Pubmed	Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis.	EGFR HDAC1 HDAC2	5.38e-06	5	285	3	24240174
Pubmed	Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity.	IL18 CASP1 NLRP3	5.38e-06	5	285	3	21471445
Pubmed	Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment.	CCND1 HDAC1 HDAC2	5.38e-06	5	285	3	15713663
Pubmed	The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells.	TONSL RAD51 PRKDC	5.38e-06	5	285	3	29478807
Pubmed	Sickle red cells as danger signals on proinflammatory gene expression, leukotriene B4 and interleukin-1 beta production in peripheral blood mononuclear cell.	IL18 CASP1 NLRP3	5.38e-06	5	285	3	27045344
Pubmed	BCR binds to the xeroderma pigmentosum group B protein.	MCF2 BCR GTF2H1	5.38e-06	5	285	3	10403766
Pubmed	Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling.	IL18 CASP1 NLRP3	5.38e-06	5	285	3	26638072
Pubmed	The lipid kinase PIP5K1C regulates pain signaling and sensitization.	PIP5K1A PIP5K1B PIP5K1C	5.38e-06	5	285	3	24853942
Pubmed	Histone deacetylases 1 and 2 cooperate in regulating BRCA1, CHK1, and RAD51 expression in acute myeloid leukemia cells.	RAD51 HDAC1 HDAC2	5.38e-06	5	285	3	28030834
Pubmed	Anti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1.	IL18 CASP1 NLRP3	5.38e-06	5	285	3	22046355
Pubmed	Identification and mapping of human histone acetylation modifier gene homologues.	KAT2A HDAC1 HDAC2	5.38e-06	5	285	3	9722949
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	USP34 MYO1E CYTH3 OBSCN KAT2A SRCAP BCR LYST DUS1L PNPLA6 SIPA1L2 MYRF DYNC1H1 SDHA RAD51 PPP1R3B ESYT1 L1CAM SPATA20 PIP5K1C PKMYT1 PIKFYVE MTOR BTBD7 PRKDC	5.41e-06	1105	285	25	35748872
Pubmed	Iris phenotypes and pigment dispersion caused by genes influencing pigmentation.	LYST HPS1 RABGGTA HPS3	5.61e-06	15	285	4	18715234
Interaction	RAC1 interactions	FNBP1 PCYT1A DLG5 IL18 MYO1E MARK3 MCF2 PAK6 ITGAV BCR LIN7A PIP4K2A PIP5K1A PLCB4 SCFD1 IMMT DOCK1 BIN1 ARHGAP23 DOCK8 ESYT1 FARSB IPO4 PIP5K1C SLC1A3 AKAP12 PIKFYVE EGFR MTOR FHOD1 TMPO CTNNB1 MAP2K2 EIF2AK2 EPB41L1	1.83e-06	1063	279	35	int:RAC1
Interaction	RHOF interactions	PCYT1A DLG5 CAND1 MYO1D MYO1E MARK3 ITGAV PIP5K1A PLCB4 SCFD1 IMMT DOCK8 ESYT1 ECPAS PIP5K1C SLC1A3 AKAP12 PIKFYVE EGFR MTOR TMPO PRKDC CTNNB1 MAP2K2 EIF2AK2 EPB41L1	2.61e-06	673	279	26	int:RHOF
Interaction	SNCA interactions	PSMC3 PSMD3 KAT2A TRIP12 MRPS22 PTK2B GRK2 SACS HPRT1 SYNE2 USP15 DYNC1H1 USP47 BIN1 XRN2 NEDD4L ESYT1 NBEA IPO4 ECPAS EGFR CADPS TMPO CTNNB1 EIF2AK2 EPB41L1	7.89e-06	716	279	26	int:SNCA
Interaction	RAC2 interactions	PCYT1A MYO1E MARK3 ITGAV HPRT1 SYNE2 PIP5K1A PLCB4 SCFD1 IMMT DOCK1 ESYT1 FARSB UFL1 SLC1A3 ADAM22 AKAP12 VPS13D EGFR MTOR PKP3 FHOD1 TMPO CTNNB1 EPB41L1	8.28e-06	674	279	25	int:RAC2
Interaction	RHOJ interactions	FNBP1 DLG5 MYO1D MYO1E MARK3 PAK6 ITGAV GFOD1 PIP5K1A PLCB4 IMMT NEDD4L DOCK8 ESYT1 PIP5K1C SLC1A3 AKAP12 EGFR MTOR FHOD1 TMPO CTNNB1 SNTB1 EPB41L1	8.79e-06	633	279	24	int:RHOJ
Interaction	RHOQ interactions	FNBP1 DLG5 MYO1D MYO1E MARK3 ITGAV GFOD1 PIP5K1A PLCB4 IMMT DOCK8 ESYT1 AKAP12 EGFR MTOR TMPO CTNNB1 SNTB1 EPB41L1	1.41e-05	442	279	19	int:RHOQ
Interaction	SYNGAP1 interactions	CAND1 PTK2B SYNE2 SIPA1L2 DYNC1H1 SHANK1 DOCK1 GRIA1 NBEA SLC1A3 ADAM22 SART1 MTOR CTNNB1 EPB41L1	2.68e-05	307	279	15	int:SYNGAP1
Interaction	HNRNPC interactions	CAND1 PKDREJ DHX8 CLK2 RHOBTB2 DKC1 USP15 USP47 RAD51 XRN2 RBM45 UFL1 APOBEC3B NLRP3 SART1 EGFR TMPO PRKDC CTNNB1 EIF2AK2 LMBRD1 HDAC1 HDAC2	2.73e-05	634	279	23	int:HNRNPC
Interaction	ANKEF1 interactions	UFL1 NXN UTP4 EPB41L1	3.23e-05	14	279	4	int:ANKEF1
Interaction	KCNA3 interactions	DLG5 RIPK1 MYO1D ABCA13 MARK3 SEC24A HLCS PSMD3 AFDN TRPM1 IMMT DYNC1H1 SDHA DOCK1 AFF2 NEDD4L ESYT1 FARSB ECPAS AKAP12 EGFR EIF4A1 TMPO PRKDC POLQ EPB41L1 DOP1A HDAC1	3.24e-05	871	279	28	int:KCNA3
Interaction	EIF2S1 interactions	UBA5 CAND1 IMMT SDHA DDX60 UFL1 TIA1 EGFR EIF4A1 PRKDC CTNNB1 MAP2K2 EIF2AK2 CAPRIN1	3.31e-05	276	279	14	int:EIF2S1
Interaction	PTEN interactions	FNBP1 PCYT1A CAND1 SETX MYO1D PSMD3 MRPS22 PTK2B SERPINB6 HPRT1 SCN10A ANAPC4 RAD51 BIN1 GPER1 RPP30 FARSB IPO4 AKAP12 PKMYT1 RAB3GAP1 CASD1 EGFR MTOR PRKDC CTNNB1 CCDC180 EIF2AK2 EPB41L1	3.96e-05	929	279	29	int:PTEN
Interaction	RND1 interactions	FNBP1 DLG5 MARK3 ITGAV IMMT PCDHGA5 ESYT1 FARSB EGFR FHOD1 TMPO CTNNB1 EPB41L1	4.15e-05	246	279	13	int:RND1
Interaction	DLGAP1 interactions	CYTH3 SHANK1 NEDD4L SYNE1 GRIA1 NBEA ADAM22 KIAA1217 CTNNB1 CAPRIN1 EPB41L1	4.40e-05	180	279	11	int:DLGAP1
Interaction	MYH10 interactions	FNBP1 PSMC3 PSMD8 ZNF512B TDRD6 USP15 USP47 ESYT1 UFL1 ECPAS SART1 TMPO CTNNB1 CAPRIN1 HDAC1 HDAC2	4.42e-05	359	279	16	int:MYH10
Interaction	RHOB interactions	FNBP1 DLG5 MYO1D MYO1E MARK3 FASTKD5 ITGAV BCR HPRT1 PIP5K1A AFDN PLCB4 SCFD1 SIPA1L2 IMMT DOCK1 NEDD4L ESYT1 FARSB NBEA SLC1A3 AKAP12 SLC5A3 EGFR CTNNB1 SNTB1 EPB41L1	4.52e-05	840	279	27	int:RHOB
Interaction	KCTD13 interactions	CAND1 MYO1D MYO1E MARK3 PSMC3 PSMD3 BCR MRPS22 PTK2B STXBP1 GRK2 PNPLA6 SACS PIP4K2A AFDN SIPA1L2 IMMT DYNC1H1 SDHA SHANK1 ADCY4 BIN1 NEDD4L ARHGAP23 DOCK8 SYNE1 L1CAM FARSB GRIA1 NBEA SLC1A3 ADAM22 CADPS KIAA1217 TMPO CTNNB1 CAPRIN1 EPB41L1	4.81e-05	1394	279	38	int:KCTD13
Interaction	MOB3C interactions	PCYT1A PSMC3 PSMD3 TRIP12 USP15 DYNC1H1 USP47 ESYT1 RPP30 UFL1 HARS2 TMPO PRKDC CTNNB1 HDAC1 HDAC2	5.21e-05	364	279	16	int:MOB3C
Interaction	AICDA interactions	USP15 RAD51 XRN2 NEDD4L RRM2B PRKDC NUP93	6.75e-05	73	279	7	int:AICDA
Interaction	USP11 interactions	CAND1 SETX MYO1D CCND1 TRIP12 CNOT8 DKC1 USP15 IMMT DYNC1H1 SDHA SPTLC2 TIA1 EGFR MTOR UTP4 TMPO CTNNB1 HDAC1 HDAC2	6.76e-05	539	279	20	int:USP11
Interaction	PIP5KL1 interactions	PIP5K1A PIP5K1B PIP5K1C	8.82e-05	7	279	3	int:PIP5KL1
Interaction	TNIK interactions	PSMD8 BCR SYNE2 DYNC1H1 SHANK1 BIN1 NEDD4L SYNE1 GRIA1 NBEA SART1 EGFR KIAA1217 CTNNB1 CAPRIN1 HDAC2	8.90e-05	381	279	16	int:TNIK
Interaction	ABCA1 interactions	DLG5 LIN7C LIN7A SHANK1 EGFR SNTB1	9.87e-05	54	279	6	int:ABCA1
Interaction	SPAG9 interactions	FNBP1 PSMC3 PSMD3 BCR USP15 USP47 RRM2B REL PIKFYVE SART1 MAP2K2 HDAC1 HDAC2	9.91e-05	268	279	13	int:SPAG9
Interaction	CIT interactions	IL18 SETX RIPK1 MYO1E ESRP1 PSMC3 TRIP12 DHX8 FBXO3 SYNE2 DKC1 IMMT DYNC1H1 SDHA RAD51 XRN2 SYNE1 DDX60 RPP30 ECPAS SLC1A3 SART1 PKP3 UTP4 EIF4A1 TMPO INTS9 MYOM2 HAGH PRKDC NUP93 CTNNB1 SPAG17 CCDC180 EIF2AK2 CAPRIN1 HDAC1 HDAC2	1.10e-04	1450	279	38	int:CIT
Interaction	NXF1 interactions	FNBP1 CAND1 MYO1E ERAP1 OBSCN PSMC3 PSMD3 CCND1 DHX8 GREB1L PNPLA6 CLK2 DKC1 PIP5K1A SCFD1 USP15 SDHA RAD51 BIN1 XRN2 POLA1 BTBD18 FARSB IPO4 ADAM22 HPS3 HARS2 GTPBP2 OTX2 EGFR MTOR DPY19L4 NUP93 CTNNB1 HDAC1 HDAC2	1.12e-04	1345	279	36	int:NXF1
Interaction	MTNR1B interactions	USP34 PSMD8 TRIP12 SYNE2 DYNC1H1 COX11 IPO4 OTX1 PRKDC	1.12e-04	135	279	9	int:MTNR1B
Interaction	DUSP15 interactions	USP34 HLCS PSMC3 PSMD3 USP47	1.13e-04	35	279	5	int:DUSP15
Interaction	LRRC31 interactions	TRIP12 PARP4 DOCK1 DDX60 IPO4 ECPAS EGFR MTOR TMPO PRKDC CAPRIN1	1.41e-04	205	279	11	int:LRRC31
Interaction	RND2 interactions	FNBP1 DLG5 MARK3 ITGAV SYNE2 SCFD1 IMMT USP47 ESYT1 RAB3GAP1 EGFR PKP3 FHOD1 TMPO CTNNB1 MAP2K2 EPB41L1	1.47e-04	440	279	17	int:RND2
Interaction	C9orf78 interactions	PCYT1A PSMD3 FASTKD5 DHX8 ASCC2 SYPL1 PIP5K1A AFDN IMMT DYNC1H1 SDHA SPTLC2 ESYT1 IPO4 ECPAS RAB3GAP1 UTP4 TMPO NUP93 HDAC1 HDAC2	1.60e-04	620	279	21	int:C9orf78
Interaction	RUVBL1 interactions	FNBP1 CAND1 MYO1E PSMC3 PSMD3 SRCAP MRPS22 DKC1 USP15 USP47 DOCK8 UFL1 EGFR MTOR TMPO INTS9 PRKDC CTNNB1 HDAC1 HDAC2	1.61e-04	575	279	20	int:RUVBL1
GeneFamily	PDZ domain containing	DLG5 SYNPO2 LIN7C LIN7A MAST4 AFDN SIPA1L2 SHANK1 ARHGAP23 RGS12 SNTB1	9.29e-07	152	198	11	1220
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	HECW1 BCR RPGRIP1 NEDD4L	6.25e-04	36	198	4	823
GeneFamily	Tudor domain containing	SPIN2A TDRD10 TDRD6 SPIN2B	6.94e-04	37	198	4	780
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE2 SYNE1	7.06e-04	4	198	2	1252
GeneFamily	CDC like kinases	CLK4 CLK2	7.06e-04	4	198	2	480
GeneFamily	Histone deacetylases, class I\|EMSY complex\|NuRD complex\|SIN3 histone deacetylase complex	HDAC1 HDAC2	7.06e-04	4	198	2	989
GeneFamily	Phospholipases\|C2 domain containing phospholipases	PLCB4 PLA2G4F PLCE1	1.10e-03	19	198	3	832
GeneFamily	Tudor domain containing\|Spindlin family	SPIN2A SPIN2B	1.17e-03	5	198	2	1089
Coexpression	GSE3039_NKT_CELL_VS_B2_BCELL_UP	ABCC4 SETX RIPK1 CYRIA MDP1 SERPINB6 PIP4K2A MPO HPS3 SLC5A3 PIKFYVE CD1D TIA1 NCKAP1L	4.17e-08	200	283	14	M6435
Coexpression	GSE45365_HEALTHY_VS_MCMV_INFECTION_BCELL_IFNAR_KO_UP	MARK3 PSMD8 CCND1 TRIP12 BIN1 NEDD4L FARSB FIGN NXN APOBEC3B PIKFYVE RAB3GAP1 BTBD7	3.01e-07	200	283	13	M9994
Coexpression	GABRIELY_MIR21_TARGETS	FNBP1 USP34 LIN7C FBXO3 SYNE2 USP47 PPP1R3B NBEA FIGN SLC5A3 PLPP1 BTBD7 KLHL15 NAA30 CAPRIN1	6.73e-07	289	283	15	M2196
Coexpression	GSE17721_0.5H_VS_24H_PAM3CSK4_BMDC_DN	CLK4 HLCS ITGAV CNOT8 PLCB4 C5 USP47 LCP2 HPS3 CD1D LMBRD1 HDAC2	2.01e-06	200	283	12	M4114
Coexpression	GSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_UP	SETX HPS1 POC1B IMMT RAD51 DOCK1 L1CAM PHTF2 NBEA TIMP4 CCNB2	6.49e-06	187	283	11	M6807
Coexpression	GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_DN	SETX RIPK1 IDO1 SYNE2 TRPM1 AFF2 DDX60 RAB3GAP1 GTPBP8 PLPP1 EIF2AK2	1.17e-05	199	283	11	M4635
Coexpression	GSE45365_WT_VS_IFNAR_KO_CD8A_DC_MCMV_INFECTION_UP	LIN7C RIPK1 ZNF512B PNPLA6 CLK2 AFDN USP47 DDX60 FHOD1 MAP2K2 HDAC1	1.17e-05	199	283	11	M9964
Coexpression	KAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP	USP34 CYTH3 CLK4 SRCAP PIP4K2A PHTF2 FARSB CD1D TIA1 HDAC1 HDAC2	1.23e-05	200	283	11	M3020
Coexpression	ZENG_GU_POST_ICB_METAGENE_39	CPA4 CYP4F8 CYP2J2 MC5R TNMD SERPINB6 PLA2G4F MYRF GPLD1 SPAG17 MUC3A	1.48e-05	204	283	11	MM17090
Coexpression	HAY_BONE_MARROW_ERYTHROBLAST	PSMC3 PSMD3 PSMD8 MRPS22 HPRT1 HPS1 DKC1 PIP5K1B TESC TRMT5 USP15 IMMT RPS6KL1 ATPAF1 SDHA NEDD4L ARHGAP23 SPTLC2 POLA1 RPP30 FARSB APOBEC3B PKMYT1 CCNB2 HAGH PRKDC NUP93 POLQ MAP2K2 CAPRIN1 HDAC2	2.13e-05	1271	283	31	M39197
Coexpression	GSE3920_UNTREATED_VS_IFNB_TREATED_ENDOTHELIAL_CELL_DN	TONSL IMMT THEMIS DPY19L1 ESYT1 DDX60 CASD1 TMPO CCNB1IP1 EIF2AK2	2.20e-05	175	283	10	M6694
Coexpression	SCHEIDEREIT_IKK_INTERACTING_PROTEINS	TRAF3IP2 RIPK1 CCND1 MAP3K8 CTNNB1 EIF2AK2	2.25e-05	53	283	6	M6303
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HDA	FNBP1 SLC24A3 PAK6 LYST PTK2B CYRIA UNC79 BIN1 NEDD4L PCDHGC4 ARHGAP23 L1CAM MUC16 GRIA1 AKAP12 CADPS EPB41L1	4.08e-05	506	283	17	M39067
Coexpression	BILD_SRC_ONCOGENIC_SIGNATURE	MARK3 ITGAV SACS CASP1 SLC5A3 TIA1	4.19e-05	59	283	6	M116
Coexpression	DESCARTES_ORGANOGENESIS_WHITE_BLOOD_CELLS	FNBP1 IL18 ERAP1 PTK2B GRK2 PIP4K2A MPO THEMIS DOCK8 MAP3K8 DDX60 CASP1 REL LCP2 APOBEC3B NLRP3 HPS3 EIF2AK2 NCKAP1L	4.50e-05	615	283	19	MM3641
Coexpression	PARENT_MTOR_SIGNALING_UP	USP34 MYO1D DUS1L ME3 CLK2 SYNE2 SDHA USP47 BIN1 SYNE1 PIP5K1C RAB3GAP1 VPS13D MTOR INTS9 CTNNB1 SNTB1 NCKAP1L	5.05e-05	567	283	18	M16909
Coexpression	SEIDEN_MET_SIGNALING	ABCC4 ITGAV CNOT8 CAPRIN1	5.62e-05	20	283	4	M16468
Coexpression	SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4	ALDH8A1 ME3 PIGA RHOBTB2 NEDD4L DPY19L1 SYNE1 REL FHOD1 EPB41L1	6.01e-05	197	283	10	M12824
Coexpression	GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_DN	CLK4 LYST MAST4 RHOBTB2 TONSL SYNE1 LBP LCP2 WDR19 CD1D	6.01e-05	197	283	10	M3438
Coexpression	GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_UP	MC5R SYNE2 PIP5K1B DPY19L1 POLA1 SYNE1 PHTF2 APOBEC3B STS TMPO	6.54e-05	199	283	10	M9410
Coexpression	GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_DN	FNBP1 CYTH3 TNMD SERPINB6 PIP4K2A PLCB4 GPLD1 SYNE1 CASP1 LBP	6.54e-05	199	283	10	M4331
Coexpression	GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_UP	CLK4 SRCAP DUS1L PIP4K2A RABGGTA FARSB IPO4 TIA1 INTS9 SNTB1	6.82e-05	200	283	10	M5821
Coexpression	GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_UP	USP34 CYTH3 CLK4 PIP4K2A PHTF2 FARSB CD1D TIA1 HDAC1 HDAC2	6.82e-05	200	283	10	M5831
Coexpression	GSE19772_CTRL_VS_HCMV_INF_MONOCYTES_UP	FNBP1 MYO1E CYTH3 ITGAV C5 AFF2 POLA1 CASP1 PHTF2 AKAP12	6.82e-05	200	283	10	M7282
Coexpression	GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_DN	PCYT1A IL18 BFAR FBXO9 XRN2 CASP1 APOBEC3B AKAP12 INTS9 DOP1A	6.82e-05	200	283	10	M8781
Coexpression	GSE30083_SP3_VS_SP4_THYMOCYTE_DN	TRAF3IP2 RIPK1 CCND1 SYNE2 C5 SCFD1 HS3ST3B1 RRM2B CASP1 UTP4	6.82e-05	200	283	10	M5037
Coexpression	KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP	CYP2J2 CYTH3 CLK4 SRCAP PIP4K2A SIPA1L2 NEDD4L IPO4 TIA1 HAGH	6.82e-05	200	283	10	M3012
Coexpression	LAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS	MYO1D MYO1E PIP5K1B DOCK8 SYNE1 PHTF2 NBEA AKAP12 PLPP1	1.38e-04	177	283	9	M39245
Coexpression	DAIRKEE_CANCER_PRONE_RESPONSE_BPA	TRIP12 SDHA FARSB MTOR NUP93	2.22e-04	51	283	5	M8655
Coexpression	PGF_UP.V1_DN	GLYAT OBSCN NPAS3 SRCAP PIP5K1A MEF2B GRIA1 PKP3 SLC14A2	2.35e-04	190	283	9	M2673
Coexpression	LAKE_ADULT_KIDNEY_C20_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_A_CORTEX	ABCC4 IL18 MYO1D ITGAV NEDD4L DOCK8 KIAA1217 SNTB1	2.57e-04	152	283	8	M39239
Coexpression	GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_UP	ERAP1 DHX8 FZD8 SYNE2 PIP5K1B RPGRIP1 BIN1 DNAH17 TTC21B	2.64e-04	193	283	9	M3484
Coexpression	PUJANA_ATM_PCC_NETWORK	USP34 PCYT1A IDO1 OBSCN MC5R PSMD3 CNOT8 GRK2 CLK2 HPS1 DKC1 PLCB4 SCFD1 IMMT GPLD1 AFF2 SPTLC2 POLA1 PHTF2 GRIA1 REL KATNA1 ADAM22 NLRP3 CD1D TMPO PRKDC SLC14A2 HDAC1 NCKAP1L	2.67e-04	1394	283	30	M9585
Coexpression	IKEDA_MIR30_TARGETS_UP	USP34 PIP4K2A PLCB4 USP15 USP47 PHTF2 GTF2H1	2.72e-04	116	283	7	M2379
Coexpression	GRYDER_PAX3FOXO1_ENHANCERS_IN_TADS	DLG5 CAND1 SETX SLC24A3 PSMD8 BFAR FZD8 PARP4 CYRIA SACS SPIN2B USP15 IMMT WSCD1 CPA5 PPP1R3B RRM2B FARSB COX11 CCNB2 KIAA1217 CAPRIN1 SNTB1 PLCE1	2.72e-04	1009	283	24	M157
Coexpression	GSE3982_EOSINOPHIL_VS_TH1_UP	GLYAT IDO1 HLCS CYRIA MGAM NXN HARS2 RAB3GAP1 BTBD7	2.85e-04	195	283	9	M5422
Coexpression	IKEDA_MIR30_TARGETS_UP	USP34 PIP4K2A PLCB4 USP15 USP47 PHTF2 GTF2H1	2.86e-04	117	283	7	MM931
Coexpression	GSE45365_HEALTHY_VS_MCMV_INFECTION_BCELL_IFNAR_KO_DN	TNMD FBXO9 GFOD1 HPRT1 STS PTGR1 UTP4 LMBRD1 ZMYM6	2.96e-04	196	283	9	M9996
Coexpression	GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_UP	SYNPO2 IL18 PIGA HS3ST3B1 NEDD4L MAP3K8 REL NLRP3 RGL4	3.07e-04	197	283	9	M5858
Coexpression	GSE3982_MAST_CELL_VS_BASOPHIL_UP	UBA5 BFAR STXBP1 GFOD1 PPP1R3A CADPS EIF4A1 CFAP74 UGGT2	3.07e-04	197	283	9	M5438
Coexpression	GSE13493_CD4INTCD8POS_VS_CD8POS_THYMOCYTE_DN	TRAF3IP2 ABCC4 IDO1 DNAJB13 TAF10 MGAM PKMYT1 MAP2K2 EIF2AK2	3.19e-04	198	283	9	M3317
Coexpression	GSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_UP	ERAP1 CCND1 LYST PTK2B CYRIA PIGA ESYT1 APOBEC3B IFNA8	3.19e-04	198	283	9	M8377
Coexpression	GSE29949_CD8_NEG_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_UP	USP34 RIPK1 SRCAP STXBP1 SLC5A3 HARS2 GTF2H1 TIMP4 MYOM2	3.19e-04	198	283	9	M8404
Coexpression	GSE360_L_MAJOR_VS_M_TUBERCULOSIS_MAC_DN	USP34 HLCS RHOBTB2 APOBEC3B CD1D ASMTL DNAH17 CTNNB1 HDAC2	3.19e-04	198	283	9	M5253
Coexpression	GSE27786_CD4_VS_CD8_TCELL_DN	KAT2A AFDN RABGGTA THEMIS FARSB IPO4 UTP4 NUP93 HDAC2	3.31e-04	199	283	9	M4821
Coexpression	GSE21379_WT_VS_SAP_KO_TFH_CD4_TCELL_DN	TRAF3IP2 FNBP1 MC5R NPAS3 CYRIA SYNE2 RRM2B NBEA CD1D	3.31e-04	199	283	9	M7498
Coexpression	GSE30083_SP2_VS_SP3_THYMOCYTE_UP	MAST4 TRPM1 SCFD1 EXOC3L2 ADCY4 IPO4 GTPBP2 OTX1 LRRC36	3.31e-04	199	283	9	M5031
Coexpression	GSE21360_PRIMARY_VS_SECONDARY_MEMORY_CD8_TCELL_UP	RPGRIP1 UBE2NL GPR21 SLC1A3 IFNA8 CFAP74 MMUT EPB41L1 HDAC2	3.31e-04	199	283	9	M7619
Coexpression	GSE3982_MAST_CELL_VS_DC_UP	HECW1 SLC24A3 TESC TRMT5 ESYT1 NBEA PKMYT1 ASMTL CCNB1IP1	3.31e-04	199	283	9	M5426
Coexpression	GSE6674_UNSTIM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN	UBA5 FNBP1 MARK3 DUS1L SYPL1 TRMT5 LCP2 PIKFYVE UTP4	3.31e-04	199	283	9	M6926
Coexpression	GSE14308_TH1_VS_INDUCED_TREG_UP	TRAF3IP2 CLK4 DNAJB13 RHOBTB2 USP15 XRN2 KATNA1 SART1 TIA1	3.43e-04	200	283	9	M3378
Coexpression	GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_UP	FNBP1 DLG5 HPRT1 DKC1 RAD51 LCP2 APOBEC3B TMPO POLQ	3.43e-04	200	283	9	M4626
Coexpression	GSE17721_POLYIC_VS_CPG_2H_BMDC_UP	FNBP1 PCYT1A BFAR CLK2 ASCC2 ANAPC4 ECPAS HARS2 GTPBP2	3.43e-04	200	283	9	M3937
Coexpression	GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDC_DN	TRAF3IP2 BFAR STXBP1 SDHA USP47 REL KATNA1 LCP2 HDAC1	3.43e-04	200	283	9	M3971
Coexpression	GSE21670_UNTREATED_VS_IL6_TREATED_CD4_TCELL_DN	PIP4K2A TESC HS3ST3B1 RABGGTA THEMIS SYNE1 RRM2B L1CAM VPS13D	3.43e-04	200	283	9	M7441
Coexpression	GSE3039_ALPHAALPHA_CD8_TCELL_VS_B2_BCELL_UP	ABCC4 CYRIA MPO RPGRIP1 DPY19L1 RBM45 L1CAM PIKFYVE GTPBP8	3.43e-04	200	283	9	M6437
Coexpression	GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_UP	PCYT1A KAT2A MDP1 DDX60 APOBEC3B AKAP12 GTPBP2 PRKDC HDAC1	3.43e-04	200	283	9	M4021
Coexpression	GSE5589_UNSTIM_VS_45MIN_LPS_STIM_MACROPHAGE_UP	TRAF3IP2 PCYT1A MYO1D CNOT8 AFDN POLA1 ECPAS NUP93 CTNNB1	3.43e-04	200	283	9	M6597
Coexpression	GRYDER_PAX3FOXO1_TOP_ENHANCERS	CAND1 SETX SLC24A3 PSMD8 BFAR CYRIA SACS USP15 IMMT WSCD1 CPA5 PPP1R3B RRM2B SNTB1	3.45e-04	441	283	14	M172
Coexpression	MODY_HIPPOCAMPUS_POSTNATAL	PTK2B STXBP1 SDHA BIN1 GRIA1	3.45e-04	56	283	5	M10332
Coexpression	MODY_HIPPOCAMPUS_POSTNATAL	PTK2B STXBP1 SDHA BIN1 GRIA1	3.45e-04	56	283	5	MM648
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 ABCA13 OBSCN UNC79 OTOA MGAM MROH2A FIGN DNAH1 ZFHX4 MYOM2 SPAG17 PLCE1	2.03e-10	184	283	13	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 ABCA13 OBSCN UNC79 OTOA MGAM MROH2A FIGN DNAH1 ZFHX4 MYOM2 SPAG17 PLCE1	2.03e-10	184	283	13	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 ABCA13 OBSCN UNC79 OTOA MGAM MROH2A FIGN DNAH1 ZFHX4 MYOM2 SPAG17 PLCE1	2.03e-10	184	283	13	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	severe-immature_Neutrophil\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ABCA13 LIN7A NTNG2 FBXO9 TESC MPO MGAM AFF2 SYNE1 FIGN POLQ RGL4	6.50e-09	200	283	12	5ee43386da8261d2e7602a152e6ba4338d844e08
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D MYO1E PIP5K1B HS3ST3B1 HS3ST3A1 DOCK8 SYNE1 PHTF2 NBEA AKAP12	7.74e-08	159	283	10	5ca96db4281abb5f646150ccf36adc66ab201c78
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D MYO1E MCF2 PIP5K1B HS3ST3B1 HS3ST3A1 DOCK8 SYNE1 PHTF2 NBEA	1.45e-07	170	283	10	876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D MYO1E MCF2 PIP5K1B HS3ST3B1 HS3ST3A1 DOCK8 SYNE1 PHTF2 NBEA	1.45e-07	170	283	10	1f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNPO2 RSPH14 COL6A5 CFAP65 CFAP47 DNAH1 SPAG17 CCDC180 SLC14A2 LRRC36	2.11e-07	177	283	10	e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH14 COL6A5 CFAP65 CFAP47 DNAH1 CFAP74 SPAG17 CCDC180 SLC14A2 LRRC36	2.22e-07	178	283	10	b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH14 COL6A5 CFAP65 CFAP47 DNAH1 CFAP74 SPAG17 CCDC180 SLC14A2 LRRC36	2.22e-07	178	283	10	579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH14 ODAD1 COL6A5 CFAP65 LBP DNAH1 CFAP74 SPAG17 CCDC180 LRRC36	3.02e-07	184	283	10	264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH14 ODAD1 COL6A5 CFAP65 LBP DNAH1 CFAP74 SPAG17 CCDC180 LRRC36	3.02e-07	184	283	10	d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH14 ODAD1 COL6A5 CFAP65 LBP DNAH1 CFAP74 SPAG17 CCDC180 LRRC36	3.02e-07	184	283	10	22010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCell	COVID-19-Epithelial-Ciliated_cells\|COVID-19 / Condition, Lineage and Cell class	RSPH14 ABCA13 ODAD1 CFAP65 DNAJB13 CFAP47 MUC16 CFAP74 SPAG17 CCDC180	4.92e-07	194	283	10	43be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	MYO1D MAST4 SYNE2 PLCB4 CFAP47 NEDD4L SYNE1 NBEA KIAA1217 SPAG17	5.16e-07	195	283	10	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	MYO1D MAST4 SYNE2 PLCB4 CFAP47 NEDD4L SYNE1 NBEA KIAA1217 SPAG17	5.16e-07	195	283	10	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 SETX TRIP12 SYNE2 USP15 DYNC1H1 DOCK8 DDX60 REL EIF2AK2	6.50e-07	200	283	10	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SETX STXBP1 MAST4 SYNE2 AFDN PLCB4 SIPA1L2 ADCY4 SPTLC2 KIAA1217	6.50e-07	200	283	10	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	DLG5 SETX SRCAP GFOD1 SYNE2 PIP4K2A SYNE1 DDX60 MYOM2 EIF2AK2	6.50e-07	200	283	10	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	severe-immature_Neutrophil\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ABCA13 LIN7A NTNG2 FBXO9 TESC MPO MGAM AFF2 POLQ RGL4	6.50e-07	200	283	10	a9b87accdaa6956116ab82427e1330e8f007ef94
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 CYRIA SYNE2 AFF2 DOCK8 SYNE1 DDX60 L1CAM LCP2	1.88e-06	175	283	9	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OBSCN NPAS3 ABCA9 FZD8 HS3ST3A1 NBEA NXN AKAP12 DNAH17	2.06e-06	177	283	9	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ODAD1 TNMD CFAP65 LBP DNAH1 SPAG17 CCDC180 SLC14A2 LRRC36	2.06e-06	177	283	9	ae01c19403a09f7ba5e4beafdfcd1b8eebdadcb7
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ODAD1 TNMD CFAP65 LBP DNAH1 SPAG17 CCDC180 SLC14A2 LRRC36	2.06e-06	177	283	9	bd3d07bdef6e903995d4bbfb6ff3a5e1d9fb70cc
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	GLYAT ABCC4 ABCA13 ALDH8A1 MAST4 SYNE2 BIN1 DOCK8 FIGN	2.84e-06	184	283	9	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IL18 MYO1D LIN7A AFDN MYRF NEDD4L NXN EGFR PLCE1	2.97e-06	185	283	9	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Ptgfr_(Postsubiculum)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TRAF3IP2 ZGRF1 NDST4 CFAP65 EXOC3L2 RAD51 CFAP47	3.07e-06	98	283	7	9865a9de11dea6db0b75dd04fee523cd2da44766
ToppCell	droplet-Lung-LUNG-1m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPAS3 STXBP1 RPS6KL1 ECM2 MROH2A LBP NXN TIMP4 PLCE1	3.24e-06	187	283	9	9c9ae8725905ba0cfe407878006ed06c2480fb72
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPAS3 STXBP1 RPS6KL1 ECM2 MROH2A LBP NXN TIMP4 PLCE1	3.24e-06	187	283	9	9e9460e57cdc9cd0a0de2866b140e06d0bc19a8f
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	ABCC4 MYO1E BCR MAST4 GFOD1 SYNE2 PLCB4 SIPA1L2 PLPP1	3.24e-06	187	283	9	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	droplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NPAS3 RPS6KL1 ECM2 MROH2A LBP NXN ZFHX4 TIMP4 PLCE1	3.39e-06	188	283	9	dc52dd2957be3f40001f0a56f3d9ac9d66ea466e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FNBP1 LRFN2 SIPA1L2 ARHGAP23 SYNE1 FIGN NXN AKAP12 PLCE1	3.39e-06	188	283	9	b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	MYO1E IDO1 MAST4 GFOD1 TDRD10 PLCB4 ADCY4 NXN PLPP1	3.39e-06	188	283	9	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FNBP1 LRFN2 SIPA1L2 ARHGAP23 SYNE1 FIGN NXN AKAP12 PLCE1	3.39e-06	188	283	9	874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell	droplet-Lung-1m-Endothelial-lymphatic_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NPAS3 RPS6KL1 ECM2 MROH2A LBP NXN ZFHX4 TIMP4 PLCE1	3.39e-06	188	283	9	2ef08313087e91985bcffc46c3798470cdeec49c
ToppCell	droplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NPAS3 RPS6KL1 ECM2 MROH2A LBP NXN ZFHX4 TIMP4 PLCE1	3.39e-06	188	283	9	1f1604b6dc0a8ad0be3d9aac0bef448459c22465
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 LIN7A NTNG2 FBXO9 MPO MGAM AFF2 SYNE1 RGL4	3.85e-06	191	283	9	6c1283d51a845cff67ed5e500f7e944165297b53
ToppCell	control-Myeloid-Mast_cell\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TRAF3IP2 ABCC4 SLC24A3 MAST4 RHOBTB2 NBEA AKAP12 CADPS EPB41L1	3.85e-06	191	283	9	afebdc59a1f884ce3f2f5fe040e16b0e95e4e7c5
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	IL18 PTK2B CYRIA DOCK8 REL LCP2 SLC1A3 NLRP3 NCKAP1L	3.85e-06	191	283	9	3b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FNBP1 SLC24A3 PIP4K2A THEMIS DOCK8 LCP2 NLRP3 CADPS NCKAP1L	3.85e-06	191	283	9	468b5149d1533f03521844d3cce8633d44eb6ed4
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA13 LIN7A NTNG2 FBXO9 TESC MPO MGAM AFF2 RGL4	4.02e-06	192	283	9	86d561c30554ff04c21801d4aaf8e3c9efe49af4
ToppCell	COVID-19_Severe-Myeloid_G-immature_Neutrophil\|COVID-19_Severe / Disease group, lineage and cell class	ABCA13 LIN7A NTNG2 FBXO9 TESC MPO MGAM AFF2 RGL4	4.02e-06	192	283	9	303deb68da2e4a75e6ee5a79478182a8bc41c7c5
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	MYO1D ESRP1 MAST4 RHOBTB2 PIP5K1B NEDD4L NXN EGFR KIAA1217	4.02e-06	192	283	9	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPB CCND1 PIP4K2A SYNE1 MROH2A BTBD7 CTNNB1 CAPRIN1 NCKAP1L	4.02e-06	192	283	9	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 PARP4 SYNE2 SYNE1 AKAP12 SLC5A3 ZFHX4 EGFR SLC14A2	4.20e-06	193	283	9	0f2167eef8203a5659c8c72e4e77646003d64797
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA13 LIN7A NTNG2 FBXO9 TESC MPO AFF2 POLQ RGL4	4.20e-06	193	283	9	ccab6a0c76f574ef7e1d6d5f1e620376daf21bbf
ToppCell	control-Myeloid-Immature_Neutrophils_2\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ABCA13 RAD51 MPO AFF2 FIGN PKMYT1 CCNB2 POLQ RGL4	4.20e-06	193	283	9	33349830e9eba506470ad3661fad5e5a283d20ca
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC4 MYO1D ABCA13 ESRP1 PARP4 SYNE2 AFDN SYNE1 EPB41L1	4.38e-06	194	283	9	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ABCA13 LIN7A NTNG2 FBXO9 TESC MPO AFF2 POLQ RGL4	4.38e-06	194	283	9	23318a1b55895b5166c6151f488a94a09b4627ff
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABCC4 ESRP1 MAST4 RHOBTB2 PIP5K1B PLA2G4F GPLD1 NEDD4L SYNE1	4.38e-06	194	283	9	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 ODAD1 CFAP47 SYNE1 MUC16 NBEA CFAP74 SPAG17 CCDC180	4.38e-06	194	283	9	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	COVID_vent-Myeloid-Monocytic-Developing_Neutrophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	ABCA13 LIN7A NTNG2 FBXO9 MPO MGAM AFF2 FIGN RGL4	4.56e-06	195	283	9	de23409b1b4146b8ae286850b829ec8dceed0117
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ESRP1 CCND1 MAST4 SYNE2 NEDD4L NBEA NXN KIAA1217 PLCE1	4.56e-06	195	283	9	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	IL18 PTK2B CYRIA PIP4K2A DOCK8 LCP2 SLC1A3 NLRP3 NCKAP1L	4.56e-06	195	283	9	ba7f85e5307d96ac5ad7c952f8d094db9ca1790c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FNBP1 CYRIA PIP4K2A THEMIS DOCK8 LCP2 SLC1A3 NLRP3 NCKAP1L	4.56e-06	195	283	9	7b6c69df943842b566a596e30bb50dbe80dccc83
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYO1D ESRP1 MAST4 PIP5K1B AFDN NEDD4L SYNE1 NXN EGFR	4.56e-06	195	283	9	9406866f99555198a9be311fbd65751b70f35446
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPK1 ABCA9 LIN7A AFF2 PCDHGA5 ECM2 PPP1R3A ZFHX4 EGFR	4.56e-06	195	283	9	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	ABCA13 MAST4 SYNE2 PLCB4 CFAP47 NEDD4L SYNE1 KIAA1217 SPAG17	4.76e-06	196	283	9	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	ABCA13 MAST4 SYNE2 PLCB4 CFAP47 NEDD4L SYNE1 KIAA1217 SPAG17	4.76e-06	196	283	9	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	FNBP1 SLC24A3 CCND1 MAST4 NEDD4L NXN KIAA1217 CTNNB1 PLCE1	4.76e-06	196	283	9	af96fb94886e9395f3e2cd0a293af29229d017fe
ToppCell	severe-unassigned\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ABCA13 NTNG2 FBXO9 MPO FIGN ADAM22 AKAP12 POLQ RGL4	4.96e-06	197	283	9	70704b149b2820b8601d2495b7cd9cbe91eda262
ToppCell	COVID-19-kidney-Macrophages\|COVID-19 / Disease (COVID-19 only), tissue and cell type	IL18 PTK2B CYRIA DOCK8 REL LCP2 SLC1A3 NLRP3 NCKAP1L	4.96e-06	197	283	9	3912301018d0863144dcfac8d1fa8adc081748d7
ToppCell	mLN-B_cell-B_cell_cycling\|B_cell / Region, Cell class and subclass	UBA5 MYO1E KIAA1958 MEF2B AFF2 NLRP3 CCNB2 KIAA1217 CCDC144A	4.96e-06	197	283	9	2071526fe46de8359ea118ff78581eb4454aa55a
ToppCell	Non-neuronal-Dividing-Radial_Glia-vRG-20\|World / Primary Cells by Cluster	NPAS3 FZD8 SYNE2 WSCD1 SLC1A3 AKAP12 ZFHX4 EGFR PLCE1	5.16e-06	198	283	9	bce0bc1e3f2257e0f42a1fa6e5b57cf71e4514ba
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ESRP1 MAST4 RHOBTB2 KIAA1958 PIP5K1B NEDD4L EGFR KIAA1217 SNTB1	5.38e-06	199	283	9	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	SYNPO2 BCR ABCA9 MAST4 SYNE2 PLCB4 DOCK1 SYNE1 EGFR	5.60e-06	200	283	9	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	CYTH3 OBSCN LIN7A SYNE2 PLCB4 TESC AFF2 FIGN PLCE1	5.60e-06	200	283	9	0c648941447c738caf62f2d71e296d6cca492c8b
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	SYNPO2 BCR ABCA9 MAST4 SYNE2 PLCB4 DOCK1 SYNE1 EGFR	5.60e-06	200	283	9	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYTH3 OBSCN LIN7A SYNE2 PLCB4 TESC AFF2 FIGN PLCE1	5.60e-06	200	283	9	522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCell	VE\|World / Condition, Cell_class and T cell subcluster	SETX DUS1L GRK2 SYNE2 TAF10 DDX60 TMPO MAP2K2 EIF2AK2	5.60e-06	200	283	9	8ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYTH3 OBSCN LIN7A SYNE2 PLCB4 TESC AFF2 FIGN PLCE1	5.60e-06	200	283	9	94f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYO1E IDO1 NTNG2 STXBP1 MAST4 SYNE2 AFDN SPTLC2 KIAA1217	5.60e-06	200	283	9	3585484c7e24e941708bee471ca607d8ccee74e6
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	SYNPO2 BCR ABCA9 MAST4 SYNE2 PLCB4 DOCK1 SYNE1 EGFR	5.60e-06	200	283	9	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	USP34 SETX STXBP1 MAST4 SYNE2 AFDN PLCB4 ADCY4 KIAA1217	5.60e-06	200	283	9	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	COVID-19-COVID-19_Severe-Myeloid-immature_Neutrophil\|COVID-19_Severe / Disease, condition lineage and cell class	ABCA13 LIN7A NTNG2 FBXO9 TESC MPO MGAM SYNE1 RGL4	5.60e-06	200	283	9	cbe667eda1af222467df8bfa157aa22df488f133
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	RSPH14 ODAD1 CFAP65 DNAJB13 CFAP47 DNAH1 CFAP74 SPAG17 CCDC180	5.60e-06	200	283	9	31d75c26055177d656df1fbb10b764cebd61e122
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	SYNPO2 BCR ABCA9 MAST4 SYNE2 PLCB4 DOCK1 SYNE1 EGFR	5.60e-06	200	283	9	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	RSPH14 ODAD1 CFAP65 DNAJB13 CFAP47 DNAH1 CFAP74 SPAG17 CCDC180	5.60e-06	200	283	9	e1dce91c6c531bb212002a14705e496d77ad3490
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	SYNPO2 BCR ABCA9 MAST4 SYNE2 PLCB4 DOCK1 SYNE1 EGFR	5.60e-06	200	283	9	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DLG5 MYO1D ABCA13 SYNE2 AFDN MUC16 EGFR KIAA1217 EPB41L1	5.60e-06	200	283	9	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	Hematolymphoid-Endothelial\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	SYNPO2 BCR ABCA9 MAST4 SYNE2 PLCB4 DOCK1 SYNE1 EGFR	5.60e-06	200	283	9	7136936d05ab344a560cf159684c881063b5430d
ToppCell	COVID-CD4-CD4_Treg\|COVID / Condition, Cell_class and T cell subcluster	ME3 MAST4 SPIN2B CPA5 DDX60 PHTF2 IPO4 CCDC180	8.28e-06	159	283	8	037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCell	droplet-Marrow-BM-30m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1D CYTH3 CYRIA PNPLA6 KIAA1958 USP27X NLRP3 UGGT2	9.50e-06	162	283	8	75df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1E MCF2 GFOD1 PIP5K1B HS3ST3A1 CPA5 DOCK8 PHTF2	1.04e-05	164	283	8	b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IL18 SACS PIP5K1B DOCK8 SPTLC2 MAP3K8 SNTB1 PLCE1	1.09e-05	165	283	8	dc570154baed59ed109e5369589448e075ba66a9
ToppCell	Thalamus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	RSPH14 OTOA DYNLT2 SPAG17 CCDC180 SLC14A2 LRRC36	1.31e-05	122	283	7	aca079f2f033cc1ac13c4ee02d490b6a514cbd5c
ToppCell	Thalamus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)--\|Thalamus / BrainAtlas - Mouse McCarroll V32	RSPH14 OTOA DYNLT2 SPAG17 CCDC180 SLC14A2 LRRC36	1.31e-05	122	283	7	ac38130010f76648757eac700a8039f3960ddde3
ToppCell	Thalamus-Macroglia-CSF_related-EPENDYMAL\|Thalamus / BrainAtlas - Mouse McCarroll V32	RSPH14 OTOA DYNLT2 SPAG17 CCDC180 SLC14A2 LRRC36	1.31e-05	122	283	7	7ab0b63244116e74c5783c3293cf08224d094d0a
ToppCell	Thalamus-Macroglia-CSF_related\|Thalamus / BrainAtlas - Mouse McCarroll V32	RSPH14 OTOA DYNLT2 SPAG17 CCDC180 SLC14A2 LRRC36	1.31e-05	122	283	7	eb944243424460bf5c66aced3ed7b7a1b6486ac7
ToppCell	Thalamus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)\|Thalamus / BrainAtlas - Mouse McCarroll V32	RSPH14 OTOA DYNLT2 SPAG17 CCDC180 SLC14A2 LRRC36	1.31e-05	122	283	7	9b0d6b0a394560ff5aadcd3b21519c2393e6def8
ToppCell	severe-Myeloid-Eosinophils\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	IDO1 SLC24A3 PNPLA6 GFOD1 ESYT1 SYNE1 AKAP12 SNTB1	1.35e-05	170	283	8	863f0266d5837cdbc3e09a3fe6a99dd3e6261674
ToppCell	COVID-19-kidney-PEC\|kidney / Disease (COVID-19 only), tissue and cell type	SACS PLCB4 SIPA1L2 MYRF SYNE1 FIGN AKAP12 PLCE1	1.47e-05	172	283	8	36a96714a0eb6ac438648135336c9791881ddadb
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH14 COL6A5 TNMD CNGA4 CFAP47 CCDC180 SLC14A2 LRRC36	1.53e-05	173	283	8	a7cc63bb3ab41feb9e4072700d44dbbbc62c47c6
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSPH14 COL6A5 TNMD CNGA4 CFAP47 CCDC180 SLC14A2 LRRC36	1.53e-05	173	283	8	e3e3a67a5a93ef4475224a256d45ae24526383cc
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 HS3ST3A1 DOCK8 SYNE1 PHTF2 FIGN AKAP12 CADPS	1.66e-05	175	283	8	1b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MYO1D MYO1E ALDH8A1 GPLD1 APOBEC3B PKMYT1 CCNB2 POLQ	1.66e-05	175	283	8	89bf89466191da14896ed8928027f5b911436c22
ToppCell	droplet-Liver-nan-3m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERAP1 ABCA9 ADCY4 RBM45 DDX60 HPS3 CCDC180	1.70e-05	127	283	7	39fa20a55de3af1a62ab5dfa4877879db3935ac2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 PARP4 SYNE1 FIGN RGS12 EGFR DNAH17 SNTB1	1.73e-05	176	283	8	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	severe-unassigned\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ABCA13 NTNG2 MPO FIGN ADAM22 POLQ RGL4	1.79e-05	128	283	7	bef9cf0078fa8498d63f0723f1fa4a3c92405e10
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_GGH\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC24A3 HS3ST3B1 HS3ST3A1 FIGN RGS12 PKMYT1 EGFR PLCE1	1.81e-05	177	283	8	d7976eac7e27044f6a859cc0c3398d08576e8c01
Drug	dimethyl phthalate	TRAF3IP2 ABCC4 SETX MARK3 SLC24A3 CCND1 SERPINB6 PNPLA6 FBXO3 PIP5K1B DYNC1H1 RAD51 MGAM BIN1 RRM2B GRIA1 FIGN SLC1A3 RGS12 PTGR1 CADPS CCNB2 CTNNB1 EIF2AK2 HDAC1	3.36e-06	714	282	25	ctd:C024629
Drug	manganese chloride	IL18 ERAP1 ITGAV ABCA9 ME3 PTK2B TRPM1 USP15 SDHA MPO NEDD4L SLC1A3 GTF2H1 EGFR PTGR1 MTOR CCNB2 CTNNB1 PLCE1	4.67e-06	456	282	19	ctd:C025340
Drug	CID11987713	CCND1 BCR TONSL SPIN2A SPIN2B DYNC1H1 CASP1 REL NBEA TIA1 EGFR CTNNB1	4.73e-06	190	282	12	CID011987713
Drug	Go6976	MARK3 CCND1 PTK2B GRK2 TONSL GPLD1 PIKFYVE STS PLPP1 EGFR PRKDC MAP2K2	4.73e-06	190	282	12	CID000003501
Drug	4-hydroxynonenal	IL18 MARK3 PSMC3 PSMD8 CCND1 TONSL PLCB4 MPO ADCY4 CASP1 COX11 REL SLC1A3 EGFR PTGR1 MTOR PRKDC CTNNB1 PLCE1	7.41e-06	471	282	19	CID000001693
Drug	bosutinib	CCND1 BCR PTK2B EGFR MTOR CTNNB1	1.23e-05	42	282	6	CID005328940
Drug	saracatinib	CCND1 PTK2B EGFR MTOR CTNNB1	1.82e-05	27	282	5	CID010302451
Drug	erionite	CASP1 NLRP3 EGFR	1.85e-05	5	282	3	ctd:C083174
Drug	geldanamicin	RIPK1 CCND1 BCR PTK2B GRK2 HPRT1 TONSL POLA1 CASP1 LBP PIKFYVE EGFR MTOR MYOM2 MAP2K2 EIF2AK2	1.87e-05	373	282	16	CID000003460
Drug	pyrophosphate	GLYAT PCYT1A MYO1D MYO1E HLCS HPRT1 AFDN PLCB4 TAF10 IMMT SDHA ANAPC4 MGAM UBE2NL ADCY4 POLA1 FARSB HARS2 GTF2H1 PLPP1 POLQ PLCE1	2.44e-05	654	282	22	CID000001023
Drug	1-Butanol	CCND1 PTK2B PIP5K1A C5 STS EGFR MTOR	2.56e-05	70	282	7	ctd:D020001
Drug	H2O2	IL18 IDO1 PSMC3 CCND1 TNMD PTK2B GRK2 HPRT1 TONSL PIP5K1B PLCB4 IMMT MPO GPLD1 ADCY4 PPP1R3B POLA1 RRM2B CASP1 COX11 REL SPATA20 PIKFYVE GTF2H1 PLPP1 EGFR MTOR TMPO CTNNB1 POLQ MAP2K2 PLCE1	2.95e-05	1183	282	32	CID000000784
Drug	AC1Q6S3U	CCND1 MPO POLA1 RRM2B CASP1 SLC1A3 EGFR ASMTL PRKDC MUC3A	3.05e-05	159	282	10	CID000000689
Drug	LY 294002; Up 200; 10uM; PC3; HT_HG-U133A	MYO1D ERAP1 GRK2 MAST4 RHOBTB2 MYRF DDX60 AKAP12 WDR19 TIA1 PKP3	3.22e-05	194	282	11	1239_UP
Drug	Finasteride [98319-26-7]; Down 200; 10.8uM; HL60; HT_HG-U133A	SRCAP CYRIA PLCB4 C5 MYRF BIN1 NBEA STS BTBD7 SNTB1 DOP1A	3.22e-05	194	282	11	2206_DN
Drug	Thioguanosine [85-31-4]; Down 200; 12.6uM; HL60; HT_HG-U133A	ERAP1 SEC24A BCR STXBP1 FBXO9 RHOBTB2 HPS1 RAB3GAP1 VPS13D TIA1 INTS9	3.22e-05	194	282	11	1264_DN
Drug	Aminohippuric acid [61-78-9]; Down 200; 20.6uM; MCF7; HT_HG-U133A	FNBP1 RSPH14 HLCS LIN7A TESC HS3ST3A1 GPER1 PHTF2 ADAM22 RGS12 VPS13D	3.54e-05	196	282	11	5394_DN
Drug	Metyrapone [54-36-4]; Down 200; 17.6uM; HL60; HT_HG-U133A	PCYT1A SEC24A KAT2A LYST LIN7A ZNF512B HPS1 PLCB4 PHTF2 PIP5K1C BTBD7	3.71e-05	197	282	11	3070_DN
Drug	Alprostadil [745-65-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A	FNBP1 HECW1 NPAS3 RHOBTB2 BIN1 AFF2 MAP3K8 ADAM22 RGS12 VPS13D DNAH17	3.71e-05	197	282	11	7358_UP
Drug	splitomicin; Down 200; 20uM; PC3; HG-U133A	SETX HPS1 DOCK1 GPLD1 NEDD4L UFL1 ECPAS ADAM22 PKMYT1 SNTB1 EPB41L1	3.88e-05	198	282	11	661_DN
Drug	AC1OAGKB	CYTH3 CCND1 BCR PTK2B GRK2 RAD51 DOCK1 PIKFYVE EGFR MTOR CTNNB1	3.88e-05	198	282	11	CID006857406
Drug	Glimepiride [93479-97-1]; Up 200; 8.2uM; MCF7; HT_HG-U133A	GLYAT PTK2B CYRIA GRK2 SCN10A RAD51 GPER1 SPTLC2 DDX60 SLC5A3 DOP1A	4.07e-05	199	282	11	4973_UP
Drug	Phentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A	RSPH14 HLCS SRCAP MAST4 C5 HS3ST3A1 BIN1 BTBD7 DNAH17 CTNNB1 EPB41L1	4.07e-05	199	282	11	3860_DN
Drug	Disopyramide [3737-09-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A	TRAF3IP2 USP34 ABCC4 SLC24A3 FBXO9 MAST4 HPS1 WDR19 MTOR BTBD7 EPB41L1	4.07e-05	199	282	11	7439_UP
Drug	Ornidazole [16773-42-5]; Up 200; 18.2uM; MCF7; HT_HG-U133A	GLYAT HECW1 GREB1L GRK2 WSCD1 SPTLC2 ADAM22 VPS13D STS ZFHX4 PLCE1	4.26e-05	200	282	11	2272_UP
Drug	Pentetic acid [67-43-6]; Down 200; 10.2uM; MCF7; HT_HG-U133A	HLCS SRCAP HPS1 C5 GPLD1 ADAM22 RGS12 SLC5A3 WDR19 STS ZMYM6	4.26e-05	200	282	11	5264_DN
Drug	ERK inhibitor	IL18 CCND1 PTK2B TONSL AKAP12 PIKFYVE EGFR TIMP4 MTOR MAP2K2	4.41e-05	166	282	10	CID001249835
Drug	methyl ethyl ketone	IL18 CYP2J2 MARK3 CCND1 ITGAV BCR PTK2B GRK2 TONSL SCFD1 GPLD1 SPTLC2 MAP3K8 EGFR MTOR CCNB2 FHOD1 CTNNB1 SPAG17 MAP2K2	4.82e-05	587	282	20	CID000006569
Drug	4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine	RIPK1 MPO CASP1 REL EIF2AK2	5.83e-05	34	282	5	ctd:C549066
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	TRAF3IP2 FZD8 PARP4 GRK2 GPER1 SLC5A3 CASD1 PKP3 TMPO CAPRIN1	5.96e-05	172	282	10	4344_DN
Drug	Lithium	PSMD8 CCND1 PTK2B PARP4 HPRT1 MAP3K8 GRIA1 REL MTOR CCNB2 CTNNB1 SLC14A2	6.18e-05	246	282	12	ctd:D008094
Drug	benzoquinone	BCR HPRT1 TAF10 MPO POLA1 SYNE1 CASP1 LBP SLC1A3 MTOR EIF2AK2	6.34e-05	209	282	11	CID000004650
Drug	3-(2-(dimethylamino)isopropoxy)-1-hydroxybenzo(b)naphtho(2,3-d)furan-6,11-dione	CCND1 EGFR MTOR	6.34e-05	7	282	3	ctd:C560905
Drug	trovafloxacin	GLYAT IL18 CCND1 FBXO9 PIP5K1A GPLD1 NEDD4L MAP3K8 REL CASD1 STS EGFR CCNB2 TMPO CAPRIN1	6.66e-05	371	282	15	ctd:C080163
Drug	ethyl methanesulfonate	GLYAT MDP1 HPRT1 ANAPC4 RAD51 DOCK1 POLA1 WDR19	7.36e-05	111	282	8	CID000006113
Disease	Intellectual Disability	UBA5 NTNG2 SACS RHOBTB2 USP27X DYNC1H1 DOCK8 SYNE1 RRM2B FARSB GRIA1 NBEA GTPBP2 MTOR KLHL15 ZMYM6 EPB41L1	1.04e-06	447	272	17	C3714756
Disease	cervical cancer	CCND1 APOBEC3B EGFR MTOR CTNNB1	1.43e-05	34	272	5	C4048328
Disease	Uterine Cervical Neoplasm	CCND1 APOBEC3B EGFR MTOR CTNNB1	1.66e-05	35	272	5	C0007873
Disease	Schizophrenia	IL18 ABCA13 MC5R NPAS3 FASTKD5 CCND1 CFAP65 NTNG2 STXBP1 PIP4K2A TRPM1 SDHA SHANK1 LYRM4 GRIA1 SLC1A3 RGS12 MTOR HAGH CTNNB1 HDAC1 HDAC2	2.69e-05	883	272	22	C0036341
Disease	Cardiomyopathy, Familial Idiopathic	SDHA EGFR TMPO CTNNB1 MMUT	9.68e-05	50	272	5	C1449563
Disease	Lymphoma, Lymphocytic, Intermediate	CCND1 MTOR CTNNB1	1.21e-04	11	272	3	C0751958
Disease	Squamous cell carcinoma	CCND1 DOCK8 APOBEC3B EGFR PRKDC HDAC1 HDAC2	1.57e-04	124	272	7	C0007137
Disease	social communication impairment	MYO1E SCN10A DOCK1 TTC21B	2.07e-04	32	272	4	EFO_0005427
Disease	Colorectal Carcinoma	ABCC4 ABCA13 OBSCN CCND1 PAK6 ABCA9 SACS ANAPC4 SHANK1 MPO SYNE1 NXN HPS3 AKAP12 EGFR CTNNB1 SPAG17	3.10e-04	702	272	17	C0009402
Disease	Opioid use measurement	LIN7A MYOM2 SNTB1	3.25e-04	15	272	3	EFO_0009937
Disease	platelet storage pool deficiency (implicated_via_orthology)	LYST HPS1 HPS3	3.25e-04	15	272	3	DOID:2223 (implicated_via_orthology)
Disease	Liver Cirrhosis, Experimental	IL18 ERAP1 BCR DUS1L LIN7A FZD8 CYRIA FBXO9 SPIN2A PPP1R3B MAP3K8 CASP1 NBEA LBP LCP2 CCNB2 HAGH NCKAP1L	3.37e-04	774	272	18	C0023893
Disease	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	CCND1 MTOR CTNNB1	3.97e-04	16	272	3	C0334634
Disease	Inherited neuropathies	PNPLA6 SACS L1CAM SLC1A3	4.97e-04	40	272	4	C0598589
Disease	age-related macular degeneration, cataract, glaucoma	ME3 PCDHGA5	5.02e-04	4	272	2	EFO_0001365, MONDO_0005041, MONDO_0005129
Disease	Malignant neoplasm of cecum	CCND1 CTNNB1	5.02e-04	4	272	2	C0153437
Disease	Jeune thoracic dystrophy	WDR19 TTC21B	5.02e-04	4	272	2	cv:C0265275
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE2 SYNE1	5.02e-04	4	272	2	cv:CN293514
Disease	bronchiolo-alveolar adenocarcinoma (is_marker_for)	CCND1 EGFR	5.02e-04	4	272	2	DOID:4926 (is_marker_for)
Disease	Cecal Neoplasms	CCND1 CTNNB1	5.02e-04	4	272	2	C0007528
Disease	Endometrioma	ABCC4 IDO1 HS3ST3B1 NEDD4L EGFR HDAC1 HDAC2	7.65e-04	161	272	7	C0269102
Disease	Endometriosis	ABCC4 IDO1 HS3ST3B1 NEDD4L EGFR HDAC1 HDAC2	7.65e-04	161	272	7	C0014175
Disease	calcium measurement	CPA4 ABCC4 CCND1 ABCA9 FBXO3 HPRT1 SYNE2 HPS1 PIP5K1A PIP5K1B EXOC3L2 PHTF2 RGS12 POLQ PLCE1	7.98e-04	628	272	15	EFO_0004838
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE2 SYNE1	8.31e-04	5	272	2	C0410190
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE2 SYNE1	8.31e-04	5	272	2	C1450051
Disease	prostaglandin reductase 1 measurement	ECPAS PTGR1	8.31e-04	5	272	2	EFO_0801932
Disease	status epilepticus (implicated_via_orthology)	IL18 CCND1 MTOR	9.11e-04	21	272	3	DOID:1824 (implicated_via_orthology)
Disease	cancer (implicated_via_orthology)	CAND1 TRIP12 PIP4K2A PIP5K1A PIP5K1B PIP5K1C MTOR CTNNB1 MAP2K2	9.11e-04	268	272	9	DOID:162 (implicated_via_orthology)
Disease	Cardiomyopathy, Dilated	SDHA EGFR TMPO CTNNB1	9.99e-04	48	272	4	C0007193
Disease	asthma (is_marker_for)	IL18 C5 MPO CASP1 EGFR HDAC2	1.14e-03	126	272	6	DOID:2841 (is_marker_for)
Disease	JT interval, response to sulfonylurea	ME3 PCDHGA5 SNTB1	1.20e-03	23	272	3	EFO_0007885, EFO_0007922
Disease	Rheumatoid Arthritis	ABCC4 IL18 GRK2 MPO REL STS TMPO	1.20e-03	174	272	7	C0003873
Disease	Malignant Neoplasms	IL18 CCND1 APOBEC3B EGFR MTOR CTNNB1	1.23e-03	128	272	6	C0006826
Disease	Emery-Dreifuss muscular dystrophy	SYNE2 SYNE1	1.24e-03	6	272	2	cv:C0410189
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE2 SYNE1	1.24e-03	6	272	2	C0410189
Disease	response to antineoplastic agent, response to doxorubicin	ME3 PCDHGA5	1.24e-03	6	272	2	GO_0097327, GO_1902520
Disease	paroxysmal nocturnal hemoglobinuria (is_implicated_in)	PIGA C5	1.24e-03	6	272	2	DOID:0060284 (is_implicated_in)
Disease	pulmonary emphysema (biomarker_via_orthology)	IL18 HDAC2	1.24e-03	6	272	2	DOID:9675 (biomarker_via_orthology)
Disease	Cancer of Head	RAD51 APOBEC3B EGFR	1.36e-03	24	272	3	C0751177
Disease	disease free survival, response to mepolizumab	HS3ST3A1 LCP2 NLRP3	1.36e-03	24	272	3	EFO_0000409, EFO_0008459
Disease	Head Neoplasms	RAD51 APOBEC3B EGFR	1.36e-03	24	272	3	C0018675
Disease	Upper Aerodigestive Tract Neoplasms	RAD51 APOBEC3B EGFR	1.36e-03	24	272	3	C0887900
Disease	Neck Neoplasms	RAD51 APOBEC3B EGFR	1.53e-03	25	272	3	C0027533
Disease	Cancer of Neck	RAD51 APOBEC3B EGFR	1.53e-03	25	272	3	C0746787
Disease	Neurodevelopmental Disorders	SRCAP TRIP12 STXBP1 DOCK8 CTNNB1	1.72e-03	93	272	5	C1535926
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE2 SYNE1	1.72e-03	7	272	2	C0751337
Disease	invasive lobular carcinoma (is_marker_for)	CCND1 CTNNB1	1.72e-03	7	272	2	DOID:3457 (is_marker_for)
Disease	MASA syndrome (implicated_via_orthology)	TRPM1 L1CAM	1.72e-03	7	272	2	DOID:0060246 (implicated_via_orthology)
Disease	acute kidney failure (implicated_via_orthology)	MPO CASP1 MTOR	1.92e-03	27	272	3	DOID:3021 (implicated_via_orthology)
Disease	Adenocarcinoma of large intestine	RIPK1 GRK2 EGFR PRKDC CTNNB1	1.98e-03	96	272	5	C1319315
Disease	chronic obstructive pulmonary disease (biomarker_via_orthology)	MPO EGFR HDAC2	2.14e-03	28	272	3	DOID:3083 (biomarker_via_orthology)
Disease	melanoma	CCND1 PTK2B PIP4K2A PLCB4 PKMYT1 CTNNB1 MAP2K2 HDAC2	2.23e-03	248	272	8	C0025202
Disease	clear cell renal cell carcinoma (is_implicated_in)	PAK6 MAP3K8	2.29e-03	8	272	2	DOID:4467 (is_implicated_in)
Disease	urticaria (is_implicated_in)	IL18 NLRP3	2.29e-03	8	272	2	DOID:1555 (is_implicated_in)
Disease	Attached earlobe	MRPS22 KIAA1217	2.29e-03	8	272	2	HP_0009907
Disease	Retinal Dystrophies	RPGRIP1 OTX2	2.29e-03	8	272	2	C0854723
Disease	neurodegenerative disease (implicated_via_orthology)	MARK3 PNPLA6 DYNC1H1 SDHA GRIA1 SLC1A3	2.32e-03	145	272	6	DOID:1289 (implicated_via_orthology)
Disease	Adenoid Cystic Carcinoma	SLC24A3 CCND1 SRCAP PRKDC MAP2K2	2.37e-03	100	272	5	C0010606
Disease	Strabismus	RPGRIP1 CADPS KIAA1217	2.37e-03	29	272	3	HP_0000486
Disease	pancreatic ductal carcinoma (is_marker_for)	CCND1 L1CAM MUC3A HDAC1	2.44e-03	61	272	4	DOID:3587 (is_marker_for)
Disease	cutaneous melanoma, hair color	MARK3 BCR SYNE2 AKAP12	2.59e-03	62	272	4	EFO_0000389, EFO_0003924
Disease	NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE	MYO1E NUP93 PLCE1	2.62e-03	30	272	3	C1868672
Disease	transitional cell carcinoma (is_marker_for)	CCND1 REL EGFR CTNNB1	2.75e-03	63	272	4	DOID:2671 (is_marker_for)
Disease	obsessive-compulsive symptom measurement	MGAM MEF2B CADPS	2.88e-03	31	272	3	EFO_0007802
Disease	bacterial pneumonia (is_marker_for)	GRK2 MPO	2.92e-03	9	272	2	DOID:874 (is_marker_for)
Disease	autism spectrum disorder (implicated_via_orthology)	NDST4 LRFN2 SHANK1 MEF2B NBEA CTNNB1	2.93e-03	152	272	6	DOID:0060041 (implicated_via_orthology)
Disease	Alcoholic Intoxication	IL18 MPO LBP	3.15e-03	32	272	3	C0001969
Disease	Squamous cell carcinoma of lung	MAST4 EGFR PRKDC	3.15e-03	32	272	3	C0149782
Disease	Dupuytren Contracture	MYO1D MYO1E DHX8 HS3ST3A1 ADCY4	3.31e-03	108	272	5	EFO_0004229
Disease	Head and Neck Neoplasms	RAD51 APOBEC3B EGFR	3.45e-03	33	272	3	C0018671
Disease	retinal degeneration (implicated_via_orthology)	PLCB4 OTX1 OTX2	3.45e-03	33	272	3	DOID:8466 (implicated_via_orthology)
Disease	Status Epilepticus	PTK2B RRM2B CASP1 EIF2AK2	3.62e-03	68	272	4	C0038220
Disease	alopecia areata (is_marker_for)	HDAC1 HDAC2	3.63e-03	10	272	2	DOID:986 (is_marker_for)
Disease	primary biliary cholangitis (is_implicated_in)	CENPB UTP4	3.63e-03	10	272	2	DOID:12236 (is_implicated_in)
Disease	linguistic error measurement, specific language impairment	HLCS RTL1	3.63e-03	10	272	2	EFO_0007798, EFO_1001510
Disease	nephritis (implicated_via_orthology)	CYP2J2 PTK2B	3.63e-03	10	272	2	DOID:10952 (implicated_via_orthology)
Disease	Hermanski-Pudlak Syndrome	HPS1 HPS3	3.63e-03	10	272	2	C0079504
Disease	transcription factor IIIb 90 kda subunit measurement	LBP PIKFYVE	3.63e-03	10	272	2	EFO_0020778
Disease	Hermansky-Pudlak syndrome	HPS1 HPS3	3.63e-03	10	272	2	cv:C0079504
Disease	renal hypertension (biomarker_via_orthology)	CYP2J2 TIMP4	3.63e-03	10	272	2	DOID:1073 (biomarker_via_orthology)
Disease	neutrophil count, eosinophil count	MYO1E PSMD3 EXOC3L2 MPO ARHGAP23 DOCK8 NLRP3	3.75e-03	213	272	7	EFO_0004833, EFO_0004842
Disease	acute lymphoblastic leukemia (is_marker_for)	CCND1 HDAC1 HDAC2	3.75e-03	34	272	3	DOID:9952 (is_marker_for)
Disease	LDL peak particle diameter measurement, total fat intake measurement	CPA4 FNBP1 FIGN	3.75e-03	34	272	3	EFO_0007677, EFO_0007678
Disease	Kartagener Syndrome	ODAD1 DNAJB13 DNAH1	4.08e-03	35	272	3	C0022521
Disease	Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus	ODAD1 DNAJB13 DNAH1	4.08e-03	35	272	3	C4551906
Disease	Polynesian Bronchiectasis	ODAD1 DNAJB13 DNAH1	4.08e-03	35	272	3	C4317124
Disease	epilepsy (implicated_via_orthology)	RIPK1 SLC24A3 SCN10A DYNC1H1 L1CAM SLC1A3	4.13e-03	163	272	6	DOID:1826 (implicated_via_orthology)
Disease	family history of Alzheimer’s disease	PTK2B LRFN2 EXOC3L2 BIN1	4.23e-03	71	272	4	EFO_0009268
Disease	gastric adenocarcinoma (is_implicated_in)	ABCA13 PLCE1	4.41e-03	11	272	2	DOID:3717 (is_implicated_in)
Disease	Jeune thoracic dystrophy	WDR19 TTC21B	4.41e-03	11	272	2	C0265275
Disease	early infantile epileptic encephalopathy (implicated_via_orthology)	UBA5 STXBP1	4.41e-03	11	272	2	DOID:0050709 (implicated_via_orthology)
Disease	chemotherapy-induced alopecia, response to antimicrotubule agent	ME3 PCDHGA5	4.41e-03	11	272	2	EFO_0005260, EFO_0005400
Disease	Primary ciliary dyskinesia	ODAD1 DNAJB13 DNAH1	4.42e-03	36	272	3	cv:C0008780
Disease	Adenocarcinoma	CCND1 EGFR MTOR CTNNB1 PLCE1	4.48e-03	116	272	5	C0001418
Disease	Carcinoma, Granular Cell	CCND1 EGFR MTOR CTNNB1 PLCE1	4.48e-03	116	272	5	C0205644
Disease	Adenocarcinoma, Tubular	CCND1 EGFR MTOR CTNNB1 PLCE1	4.48e-03	116	272	5	C0205645
Disease	Adenocarcinoma, Oxyphilic	CCND1 EGFR MTOR CTNNB1 PLCE1	4.48e-03	116	272	5	C0205642
Disease	Carcinoma, Cribriform	CCND1 EGFR MTOR CTNNB1 PLCE1	4.48e-03	116	272	5	C0205643
Disease	Adenocarcinoma, Basal Cell	CCND1 EGFR MTOR CTNNB1 PLCE1	4.48e-03	116	272	5	C0205641
Disease	pentachlorophenol measurement	NTNG2 PIP4K2A MUC16 NLRP3	4.67e-03	73	272	4	EFO_0022071

Protein segments in the cluster

Peptide	Gene	Start	Entry
GTFKRELLLAEEYPM	UBE2NL	51	Q5JXB2
TAEQPYFIEAREKMA	TTC21B	681	Q7Z4L5
AVLDYVMTRPDLDKT	ABHD13	171	Q7L211
SRLAAEVYKDMPETS	AFDN	196	P55196
EVYKDMPETSFTRTI	AFDN	201	P55196
AVREMLPDTYISKTI	EXOC3L2	111	Q2M3D2
TRYKFVIPEVLSEMK	ERICH6B	621	Q5W0A0
YMEKLLAETVAPAVR	ESYT1	156	Q9BSJ8
YFMLPTVITDIKDES	ALDH8A1	371	Q9H2A2
LYSFLPEVTRMARKF	ANAPC4	241	Q9UJX5
PAETRDFIDAYLKEM	CYP2J2	271	P51589
KEILRYLMDPDTFTF	APOBEC3B	186	Q9UH17
YIPLTDLSFQMVDEL	BCR	756	P11274
VVPLSEYDAVEREKM	AKAP12	846	Q02952
IESMLEYEPAKRLTL	CLK2	456	P49760
ERFSSLMVYKLPVED	ABCA9	1546	Q8IUA7
KSPYTMYSETVELLR	AFF2	1121	P51816
SFYEAAIPEMESAIK	ASCC2	281	Q9H1I8
VDYDSDMPRKITEVL	GTPBP2	146	Q9BX10
ISENPLITLREFMKY	ADAM22	301	Q9P0K1
FPEIDKTVRYAQMLE	DUS1L	151	Q6P1R4
YFTELILRPIEMSDE	ABCA13	1521	Q86UQ4
EERTKKEMIDFPYSF	ABCA13	2866	Q86UQ4
EMEKEYRLSAIPAFK	ADCY4	571	Q8NFM4
MVFYSDEKERVIPLL	DOP1A	2051	Q5JWR5
AMNYLDRFLSLEPVK	CCND1	81	P24385
FALDTEYMVLELSEP	LVRN	181	Q6Q4G3
AEVIEKTSYLMRPEV	CCDC180	286	Q9P1Z9
LDEFYKLVDPERDMS	CAPRIN1	186	Q14444
EPSIRSVMQKYLEDR	GRK2	36	P25098
PDIDKLDVATMTEYL	ESRP1	151	Q6NXG1
LLMLYTRKFESTDPR	NUP93	531	Q8N1F7
DSRPAMAIFELLDYI	MAP2K2	311	P36507
IFETYEKIPLLMDFD	RAD51AP2	681	Q09MP3
PQRMYSVLTKEDFRL	RAB3GAP1	956	Q15042
TRIFVMIPKSYTEED	RBM45	121	Q8IUH3
MIPKSYTEEDLREKF	RBM45	126	Q8IUH3
KAMYIDTEGTFRPER	RAD51	156	Q06609
AMSYRRAEVLALPFK	INTS9	496	Q9NV88
RRYEKIEIMPELADS	INTS9	511	Q9NV88
YEVIRFPIDLKTMTE	KAT2A	766	Q92830
IRYSMPEELDKGSFV	PCDHGA5	31	Q9Y5G8
RDTKETTAYMPVDFE	KCTD19	526	Q17RG1
SVMAFDRYKAIINPL	OR5W2	116	Q8NH69
TKQLDMVYDITPELA	OTOA	291	Q7RTW8
LFAPLVVRYVDLMES	CADPS	976	Q9ULU8
SFLTIELRDVSPYMD	MUC16	4011	Q8WXI7
RISKSDFYEIMRAQP	PNPLA6	606	Q8IY17
KVMLETPEYRSRFTS	CYRIA	231	Q9H0Q0
AAVLFRMSEDKPQDY	CTNNB1	656	P35222
SKPEEIDESLRRYFM	FIGN	631	Q5HY92
MLVTKAVVYRETDPS	EPB41L1	856	Q9H4G0
KPLTYENMDVLFSFR	IDO1	141	P14902
YFSDSPVQAMKRLRD	PAK6	601	Q9NQU5
YMEIDAFVLLPSSSK	LBP	361	P18428
LEEMDTFLDTYTLPR	nan	426	O00370
ITMEKTPSYFVTREA	HS3ST3B1	196	Q9Y662
MALTDVDETYRKPVL	LSM11	196	P83369
VRYTPKVLEEMEARF	LIN7A	186	O14910
VRYTPKVLEEMESRF	LIN7C	171	Q9NUP9
MARLPKLAVFDLDYT	MDP1	1	Q86V88
DYIKFLRSIRPDNMS	HDAC1	71	Q13547
EFTYNPFMRVREKTV	HAGH	266	Q16775
ILLSLFEEEIMSYVP	HECW1	1171	Q76N89
SALLPVDIFLVSYMK	LMBRD1	61	Q9NUN5
PVDKQDAYRMLSRLS	ASMTL	101	O95671
EVSMYSREEPLQLKL	CFAP65	866	Q6ZU64
DYMERQLDFTLSPKF	MGAM	1281	O43451
IDYMERQLDFTLSPK	MGAM	2176	O43451
RILYMAAETAKELTP	GLYAT	131	Q6IB77
TRESIPEDLYQKFMA	HLCS	221	P50747
LILNEMPKAEYSSLF	DDX60	16	Q8IY21
DMRVPFSELKDIKAY	CPA5	81	Q8WXQ8
VSTRHEMLPEFYKTV	CAND1	361	Q86VP6
KEEMRELAALFYSVV	ECPAS	706	Q5VYK3
QMTEDVYFPKDLRGT	MAP3K8	276	P41279
PAQIREMFDDVSYDK	ERAP1	426	Q9NZ08
FTYRIRIEMSKDALP	FBXO3	306	Q9UK99
LSPKYIKMFVLDEAD	EIF4A1	171	P60842
IEVDFSKPYVRVTME	PCYT1A	51	P49585
PEKMTREGYQVSFLD	LRRC36	266	Q1X8D7
LFIIKTERSLHEPMY	OR51G2	51	Q8NGK0
SIVVDYLVLLEMPFS	MUC3A	3081	Q02505
MELLSYFKQPVAATR	MPO	96	P05164
SKPERDVLMQDFYVV	PIP5K1B	46	O14986
DFMEKETPLRYTKTL	DPY19L1	396	Q2PZI1
IPSKYVMDQEFSRRL	DLG5	1651	Q8TDM6
LEESAMLRYAIAFPL	NCKAP1L	556	P55160
EKTIPYSDKLFEMVL	IMMT	76	Q16891
RPMKDETFGEYRSLE	L1CAM	1166	P32004
ITMEKTPSYFVTREA	HS3ST3A1	211	Q9Y663
ERDILKEMFPYEAST	TMPO	341	P42167
MASATEDPVLERYFK	POC1B	1	Q8TC44
ECTDIKILPYRSMEL	NDST4	51	Q9H3R1
GPLDREAKSSYDIMV	PCDHGC4	411	Q9Y5F7
ELIAKEDVDFLPYMS	PARP4	1196	Q9UKK3
DYSLEAPFEVLKMTE	PLA2G4F	706	Q68DD2
RAPEDFVDMVETYLK	GTPBP8	171	Q8N3Z3
TFEKMVNTLLERYPR	GREB1L	886	Q9C091
YPMSREELLSQVEKL	ODAD1	476	Q96M63
STKPERDVLMQDFYV	PIP5K1A	101	Q99755
TLYFLPREMKIDLNT	POLA1	386	P09884
DMDRVLLKYTEYSEP	MEF2B	61	Q02080
KASVIMVDELLSAYP	SLC24A3	306	Q9HC58
LFAKTRYPDIFMREE	OTX1	56	P32242
RSIPMTVDFIRLKSY	HPRT1	91	P00492
VSFEKLVYVRMSLDD	PPP1R3A	151	Q16821
VLPSDKFKDYLETMA	OBSCN	7821	Q5VST9
SVMAFDRYIAISKPL	OR4D9	116	Q8NGE8
KRRLEEDDMYSVLPE	ABCC4	36	O15439
RPLEKFVTYFTRMEQ	RGL4	441	Q8IZJ4
LRKLVDFLYTSEMEV	BTBD18	86	B2RXH4
FYATEDDRFILKQMP	PIKFYVE	1866	Q9Y2I7
VSTFLIDMERFKYPE	FZD8	296	Q9H461
DKLSRMVKEFQPYLD	DNAH1	1011	Q9P2D7
EKDIDLTRMEYIPVA	DNAH1	3436	Q9P2D7
IEFSKMARDPQRYLV	EGFR	966	P00533
FAMVKRYLTSFPIDD	CENPB	551	P07199
YSSLISEIHRKMPEF	FASTKD5	451	Q7L8L6
MSRPDFLSYLSFEKL	KLHL15	166	Q96M94
KSYVNTMDLERDEPL	BFAR	6	Q9NZS9
PVYEDLLSENRKMIT	CASD1	211	Q96PB1
EIYPIMDKSSRTRLA	CASP1	151	P29466
EVLMSLYDPVESKFI	DOCK1	241	Q14185
ETELRKATIPIFFDM	DOCK1	1096	Q14185
ILYDTVKMREFQEDP	DOCK8	1606	Q8NF50
LLLASKYEEMFSPNI	CCNB2	216	O95067
VAPRYSVMLELFDAE	DNAH17	541	Q9UFH2
RFDLPDMKETKYTVD	EIF2AK2	246	P19525
DIEFEDYTQPMKRTV	FNBP1	281	Q96RU3
EFAKMLRLSYPLELQ	CD1D	101	P15813
MQLVPDIEFKITYTR	FBXO9	121	Q9UK97
LRPNEFKYMSVIAEL	ATPAF1	296	Q5TC12
DPRMIKVDLITLSYT	COX11	246	Q9Y6N1
REVKYFSFPGELLMR	SLC1A3	76	P43003
DYQRDPAITSILEKM	CPA4	201	Q9UI42
SIYDSSMKLVREFEP	POLQ	301	O75417
IREAFLPEDSYMDVV	COL6A5	1951	A8TX70
KDVFLEMNIPYSVVR	C5	821	P01031
SEFRDKLTPITIFME	ITGAV	576	P06756
EKPSEYITAIMELSA	CYP4F8	216	P98187
LPDYVRLAMLDFVSS	C1orf112	661	Q9NSG2
RMEYKDSASLPRIQD	CCDC144B	626	Q3MJ40
IKASISRDPFYDMLA	CYTH3	376	O43739
MLKAPSFERGVYELT	DPY19L4	106	Q7Z388
FSPYVEEAKSVLDEM	BTBD7	576	Q9P203
RLPIVNFDYSMEEKF	ECM2	66	O94769
SMTDVKELIPEFFYL	LYST	3286	Q99698
NMSFRFIKRLPTEYE	MARK3	616	P27448
YEFDVILSPELKVQM	MCF2	386	P10911
QMEERLKEIITSYSP	MAST4	386	O15021
DPLIYAFRSQEMRKT	MC5R	291	P33032
FYRVLTSDVEKFMPI	ME3	121	Q16798
YSTDKLIIENRDMPR	LYRM4	76	Q9HD34
RQIAEAYDVLSDPMK	DNAJB13	46	P59910
IDREKAMSRPILYSN	DYNC1H1	2861	Q14204
MARFYSPATIFIDEI	KATNA1	296	O75449
DFGYMVKLLTDSRLP	CNOT8	161	Q9UFF9
ESPLMYEDSILAVRK	IFNA8	131	P32881
EKLFDLVRRMLEYDP	CLK4	446	Q9HAZ1
FKLDYDSMEREIAEP	FHOD1	786	Q9Y613
LQIRYLPEDFMESLK	PTK2B	131	Q14289
RMEYKDSASLPRIQD	CCDC144A	626	A2RUR9
TLVREEVIDFSKPFM	GRIA1	496	P42261
DEYIKFLRSIRPDNM	HDAC2	71	Q92769
FLRSIRPDNMSEYSK	HDAC2	76	Q92769
PDKRYAMVLFRITSV	GPR21	246	Q99679
YKLQMIEVPVLSDDS	HPS1	621	Q92902
DNAPRTIFIISMYKD	IL18	76	Q14116
MDTYLGQFPDIKSRI	BIN1	126	O00499
VRTIYESKMIEYDPE	DKC1	196	O60832
YDRTVRVFEVMLPEK	SACS	3541	Q9NZJ4
FSIPETIRRDVYKMQ	CFAP47	1556	Q6ZTR5
MLEEALRSESPYQRK	IPO4	356	Q8TEX9
EKELSGMYRRLFEPL	BVES	121	Q8NE79
RYFDKETRVLEAPMT	CFAP74	881	Q9C0B2
AFQDYIKLMPLVSEA	KIF28P	531	B7ZC32
LTTKEYMREVTTIDP	DHX8	1156	Q14562
NSPRKEVYFMAIIDI	PIP4K2A	346	P48426
ISLPEKIQSYERMEF	PPP1R3B	196	Q86XI6
ALFLTVDPYMRVAAK	PTGR1	41	Q14914
LFAKTRYPDIFMREE	OTX2	56	P32243
SVMALDRYVAISKPL	OR4D10	116	Q8NGI6
SFVKSHIRPYMDEIV	MTOR	1021	P42345
ESVYPVMTEEEFALK	MROH2A	241	A6NES4
DFVQRAMDYFPKIEI	NLRP3	641	Q96P20
AMDYFPKIEINLSTR	NLRP3	646	Q96P20
FEYGRPTVMVLEKSL	NTNG2	141	Q96CW9
AFELVYSPAIKDSTM	RPP30	151	P78346
TPIIFKEENLRTMYS	MRPS22	206	P82650
EYSQAEMKILPIRAA	RTL1	916	A6NKG5
SLYLDSRKLPMIDFV	SYPL1	141	Q16563
IYKPLLFMDLLDERT	UTP4	646	Q969X6
LKELDSPFRLYGLTM	PHTF2	736	Q8N3S3
VVLTEKDLLIYDSMP	SNTB1	346	Q13884
RLIMLDPYKIFTHDS	TRMT5	136	Q32P41
EKMCIEIVSLAFYPE	RPGRIP1	1116	Q96KN7
DLTVPFARYLAMNKV	HARS2	131	P49590
LVDFLMQLEDYTPTI	TAF10	116	Q12962
EYKNRDAISALMPLF	TDRD6	1981	O60522
MYGLPTDTIRKEFRT	PLCB4	726	Q15147
AIDSTYRKLMEDPDK	SYNE1	1111	Q8NF91
RPLQEESIMEKDYSA	SYNE2	1096	Q8WXH0
FMERYAPVAKDLASR	SDHA	326	P31040
ELAKEMSVPFYTSRI	GFOD1	41	Q9NXC2
AAAREEDPYMDTTLK	HPS3	401	Q969F9
SARAKYVMDVEEITP	NXN	401	Q6DKJ4
DIKPVTTDYFLMEEK	PLCE1	2051	Q9P212
ILYVIRDESPMKANF	SEC24A	1051	O95486
QPFMLEKDILSSYEV	TDRD10	311	Q5VZ19
YSIFADKTPEQVRME	IQCA1L	326	A6NCM1
PMRATYLDDLRSKFL	RABGGTA	416	Q92696
SKPERDVLMQDFYVV	PIP5K1C	96	O60331
PSDEVEAMTYLCRKL	PKDREJ	2186	Q9NTG1
ISVLMVSKYRDILEP	NBEA	1571	Q8NFP9
SFREKMTIPDLYFIN	GPER1	86	Q99527
MFDKTRLPYVALDVL	PLPP1	1	O14494
IQEEMAEDPLTYKSR	RHOBTB2	396	Q9BYZ6
AEDPLTYKSRLMVVV	RHOBTB2	401	Q9BYZ6
LPRFKLEESYDMESV	SERPINB6	271	P35237
PRFYEILKVMQEAAD	STS	521	P08842
ELCRIPMVEYKLDSE	SIPA1L2	1036	Q9P2F8
MLESPSVAIYIKDES	KIAA1217	226	Q5T5P2
IFDEPMDIRSAYKRL	KIAA1217	1446	Q5T5P2
VRTKLEPESYLDDMV	SETX	336	Q7Z333
EEVKRRYMLASPDVT	SLC5A3	211	P53794
YKEGDLRIMPESSES	SPIN2A	181	Q99865
SDYMDLTPVDIVGKR	NPAS3	351	Q8IXF0
DFPALYSELKIMLNT	WDR19	1296	Q8NEZ3
PIERYAMKFLEASLE	SRCAP	2311	Q6ZRS2
DITEYCPREIISLMK	RIPK1	251	Q13546
ELTFQAMSYDLLPIE	STXBP1	246	P61764
SHTFPELAYRKEMVR	FARSB	296	Q9NSD9
PALLEIVIFYSEDMS	SLC36A3	411	Q495N2
ARLEYMVKAADFPSD	SPAG17	316	Q6Q759
KSIDEGMFSAEPYLR	SHANK1	1286	Q9Y566
IVRTELSPSEEYKAM	CCNB1IP1	61	Q9NPC3
PEELRKVFITYSMDT	TRAF3IP2	406	O43734
EDFLTIMSYFRPIDT	TESC	86	Q96BS2
FLDLASLMPTDVVYV	CNGA4	116	Q8IV77
KVYDRVSVEAVLPMD	PIGA	396	P37287
EMYSLLIDTYIRDPK	RRM2B	136	Q7LG56
KREFLFNAIETMPYV	RRM2B	151	Q7LG56
FDDIDLPSAVKYLMA	PKP3	316	Q9Y446
KIYMEIDPVTRTEIF	TNMD	76	Q9H2S6
VYAREMLAVKTELPE	VSX1	191	Q9NZR4
DKTPYLTMEEITRTI	THEMIS	91	Q8N1K5
DIIESIFRTYPAVKM	GTF2H1	191	P32780
EKDYLAPTTVRQLMA	ZFHX4	3001	Q86UP3
RKITTYISFPLELDM	USP27X	321	A6NNY8
KEMIDIYSTREPQLA	PSMD3	461	O43242
MSKIPADRYRVEGSF	RGS12	576	O14924
YPEVIKLMESITDSL	SYNPO2	66	Q9UMS6
EDGRLYAVKRSMSPF	PKMYT1	131	Q99640
FRAMEVETYEKPQVA	RSPH14	316	Q9UHP6
EAFEETPMLVAVLTY	SPTLC2	61	O15270
CMTRTDLPEKIEYVF	SCN10A	146	Q9Y5Y9
EVVDSNPYSRLMALK	UBA5	46	Q9GZZ9
GDSDLMEPVFRYLAK	TONSL	1231	Q96HA7
IEAIRAEYQKMPAFL	TRIM51	176	Q9BSJ1
KEPYAREMLAISFIS	ARHGAP23	1156	Q9P227
REERPDVDKVYMTFV	SPATA20	141	Q8TB22
YKEGDLRIMPESSES	SPIN2B	181	Q9BPZ2
LETLPTEYDSRVKAM	PSMC3	161	P17980
EYLERELTMASLPFT	XRN2	311	Q9H0D6
PDSMSFIYKALERNI	GPLD1	336	P80108
YMFDLLLETRKPDQV	USP47	691	Q96K76
SRYMRDKLDTLVDFP	USP15	841	Q9Y4E8
SADPADTEKMLRYEI	TIMP4	61	Q99727
DAGTPEDKMRLFLIY	SCFD1	446	Q8WVM8
VPDMTKRDYLVDAAT	RPS6KL1	41	Q9Y6S9
VSESMDFRYLPDEKD	REL	271	Q04864
LASEYLTPEEMVTFK	SART1	386	O43290
VYEMFRKDDPRLSFT	PRKDC	1801	P78527
IIERYPEETLSLMTK	PRKDC	3471	P78527
LIKYEDSMISISRFP	ZNF234	111	Q14588
MYIRVSYDTKPDSLL	TRPM1	71	Q7Z4N2
MKDDLVPETARLNYT	ZNF512B	711	Q96KM6
PLELMFVYSLEERVE	TRBV4-3	61	A0A589
FSIAEELIKPYLVEM	ZMYM6	846	O95789
LMKEDLTPTERVYVR	ZGRF1	1751	Q86YA3
ILRKDIPSFERYMAQ	PSMD8	156	P48556
PVFAEYIKCILMDER	USP34	3211	Q70CQ2
SVKEYRMEVPSSFSE	USP34	3411	Q70CQ2
FTPEMKDLINGYIRT	WSCD1	541	Q658N2
LESFYRFVLEPELMS	UGGT2	1011	Q9NYU1
AEILMQKLPDIFSVY	TRIP12	906	Q14669
PDYSSIEIMREKLLI	TRIP12	1966	Q14669
YRKPTVELLDLDTME	SLC14A2	511	Q15849
MEIRVFPDKGYSFVR	TIA1	241	P31483
YITPAQISKEMRDEL	UFL1	56	O94874
KDIIEYLSTSFLPMA	UNC79	191	Q9P2D8
YSEMVSLFETPRKTR	VPS13D	1336	Q5THJ4
MVIFAPRYLLDNKSS	VPS13D	3396	Q5THJ4
RRPSMFEKEAYTQIL	DYNLT2	31	Q8IZS6
MEAKSPFYLTARKEA	KIAA1958	646	Q8N8K9
LSVSDIIDYFRKMPL	LCP2	496	Q13094
DEVLIYRMIPASNKA	LRFN2	461	Q9ULH4
AIFVTDRHLYKMDPT	MYO1D	876	O94832
PESLFLLEEMRERKY	MYO1E	681	Q12965
EPSMKIIADIFEYTA	MMUT	236	P22033
DIMRLITKDLSEPYS	NAA30	226	Q147X3
RSPRYAVFDLMEGKS	MYOM2	566	P54296
ELPMLTYRVDADKGF	MYRF	371	Q9Y2G1
YETFEDLREKLLMAV	NEDD4L	951	Q96PU5