Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	[heparan sulfate]-glucosamine N-sulfotransferase activity	NDST1 NDST4	8.99e-05	4	78	2	GO:0015016
GeneOntologyMolecularFunction	N-acetylglucosamine deacetylase activity	NDST1 NDST4	8.99e-05	4	78	2	GO:0050119
GeneOntologyMolecularFunction	histone H3 demethylase activity	RIOX2 KDM6B KDM1A	1.75e-04	28	78	3	GO:0141052
GeneOntologyMolecularFunction	histone demethylase activity	RIOX2 KDM6B KDM1A	2.38e-04	31	78	3	GO:0032452
GeneOntologyMolecularFunction	protein demethylase activity	RIOX2 KDM6B KDM1A	2.62e-04	32	78	3	GO:0140457
GeneOntologyMolecularFunction	histone H3K4 demethylase activity	RIOX2 KDM1A	4.15e-04	8	78	2	GO:0032453
GeneOntologyMolecularFunction	aminopeptidase activity	LTA4H DPP3 ENPEP	6.32e-04	43	78	3	GO:0004177
GeneOntologyMolecularFunction	demethylase activity	RIOX2 KDM6B KDM1A	6.77e-04	44	78	3	GO:0032451
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	ARHGEF40 RAPGEF6 MYO9A RABEP1 ECT2L RAPGEF2 PREX2 SH3BP4	8.07e-04	507	78	8	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	ARHGEF40 RAPGEF6 MYO9A RABEP1 ECT2L RAPGEF2 PREX2 SH3BP4	8.07e-04	507	78	8	GO:0030695
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	RIOX2 TYR KDM6B NOS1 KDM1A	9.78e-04	194	78	5	GO:0016705
GeneOntologyMolecularFunction	heparan sulfate sulfotransferase activity	NDST1 NDST4	1.53e-03	15	78	2	GO:0034483
GeneOntologyMolecularFunction	CARD domain binding	MAVS NOD2	1.97e-03	17	78	2	GO:0050700
GeneOntologyMolecularFunction	2-oxoglutarate-dependent dioxygenase activity	RIOX2 KDM6B KDM1A	2.10e-03	65	78	3	GO:0016706
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	ARHGEF40 RAPGEF6 ECT2L RAPGEF2 PREX2	2.11e-03	231	78	5	GO:0005085
GeneOntologyMolecularFunction	metalloexopeptidase activity	LTA4H DPP3 ENPEP	2.60e-03	70	78	3	GO:0008235
GeneOntologyMolecularFunction	myosin V binding	RAB39B RAB8A	2.73e-03	20	78	2	GO:0031489
GeneOntologyMolecularFunction	ATPase-coupled ion transmembrane transporter activity	ATP6V0A4 TCIRG1	3.93e-03	24	78	2	GO:0042625
GeneOntologyMolecularFunction	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	ATP6V0A4 TCIRG1	3.93e-03	24	78	2	GO:0044769
GeneOntologyMolecularFunction	proton-transporting ATPase activity, rotational mechanism	ATP6V0A4 TCIRG1	3.93e-03	24	78	2	GO:0046961
GeneOntologyMolecularFunction	phosphatidic acid binding	RAPGEF6 RAPGEF2	3.93e-03	24	78	2	GO:0070300
GeneOntologyCellularComponent	apical plasma membrane	RAPGEF6 SPTBN2 ATP6V0A4 KCNN4 TCIRG1 RAPGEF2 ENPEP SLC3A2	4.61e-04	487	78	8	GO:0016324
GeneOntologyCellularComponent	endocytic vesicle	RAPGEF6 RABEP1 ATP6V0A4 TCIRG1 RAPGEF2 RAB8A NOD2	5.76e-04	384	78	7	GO:0030139
GeneOntologyCellularComponent	vacuolar proton-transporting V-type ATPase, V0 domain	ATP6V0A4 TCIRG1	6.07e-04	10	78	2	GO:0000220
GeneOntologyCellularComponent	lysosome	TYR RNASE3 GPR137C ATP6V0A4 TCIRG1 UNC13D ATP10B NOS1 ENPEP SLC3A2	8.46e-04	811	78	10	GO:0005764
GeneOntologyCellularComponent	lytic vacuole	TYR RNASE3 GPR137C ATP6V0A4 TCIRG1 UNC13D ATP10B NOS1 ENPEP SLC3A2	8.46e-04	811	78	10	GO:0000323
GeneOntologyCellularComponent	proton-transporting V-type ATPase, V0 domain	ATP6V0A4 TCIRG1	8.85e-04	12	78	2	GO:0033179
Domain	HSNSD	NDST1 NDST4	9.50e-05	4	75	2	PF12062
Domain	V-type_ATPase_116kDa_su_euka	ATP6V0A4 TCIRG1	9.50e-05	4	75	2	IPR026028
Domain	Heparan_SO4_deacetylase	NDST1 NDST4	9.50e-05	4	75	2	IPR021930
Domain	V_ATPase_I	ATP6V0A4 TCIRG1	9.50e-05	4	75	2	PF01496
Domain	V-ATPase_116kDa_su	ATP6V0A4 TCIRG1	9.50e-05	4	75	2	IPR002490
Domain	CP2	TFCP2L1 TFCP2	2.36e-04	6	75	2	PF04516
Domain	CP2	TFCP2L1 TFCP2	2.36e-04	6	75	2	IPR007604
Domain	RA	RAPGEF6 MYO9A RAPGEF2	2.58e-04	31	75	3	SM00314
Domain	RA	RAPGEF6 MYO9A RAPGEF2	4.04e-04	36	75	3	PF00788
Domain	RA	RAPGEF6 MYO9A RAPGEF2	4.38e-04	37	75	3	PS50200
Domain	RA_dom	RAPGEF6 MYO9A RAPGEF2	5.52e-04	40	75	3	IPR000159
Domain	LDLRA_1	LRP12 TMPRSS15 PKD1	9.45e-04	48	75	3	PS01209
Domain	CUB	LRP12 TMPRSS15 PDGFD	1.00e-03	49	75	3	PF00431
Domain	LDLRA_2	LRP12 TMPRSS15 PKD1	1.00e-03	49	75	3	PS50068
Domain	Peptidase_M1	LTA4H ENPEP	1.02e-03	12	75	2	IPR001930
Domain	CUB	LRP12 TMPRSS15 PDGFD	1.06e-03	50	75	3	SM00042
Domain	RmlC-like_jellyroll	RIOX2 RAPGEF6 RAPGEF2	1.13e-03	51	75	3	IPR014710
Domain	-	LRP12 TMPRSS15 PDGFD	1.19e-03	52	75	3	2.60.120.290
Domain	Peptidase_M1	LTA4H ENPEP	1.21e-03	13	75	2	PF01433
Domain	Peptidase_M1_N	LTA4H ENPEP	1.21e-03	13	75	2	IPR014782
Domain	CUB	LRP12 TMPRSS15 PDGFD	1.26e-03	53	75	3	PS01180
Domain	CUB_dom	LRP12 TMPRSS15 PDGFD	1.56e-03	57	75	3	IPR000859
Domain	P-loop_NTPase	NDST1 IQCA1 MYO9A DDX60 YLPM1 NDST4 ABCF2 RAB39B RAB8A NOD2	2.02e-03	848	75	10	IPR027417
Domain	DH_1	ARHGEF40 ECT2L PREX2	2.08e-03	63	75	3	PS00741
Domain	PDZ	RAPGEF6 RAPGEF2 NOS1 PREX2	2.50e-03	141	75	4	PF00595
Domain	RhoGEF	ARHGEF40 ECT2L PREX2	2.81e-03	70	75	3	PF00621
Domain	DH_2	ARHGEF40 ECT2L PREX2	2.81e-03	70	75	3	PS50010
Domain	RasGEFN	RAPGEF6 RAPGEF2	2.88e-03	20	75	2	SM00229
Domain	DH-domain	ARHGEF40 ECT2L PREX2	2.92e-03	71	75	3	IPR000219
Domain	-	ARHGEF40 ECT2L PREX2	2.92e-03	71	75	3	1.20.900.10
Domain	-	NDST1 IQCA1 DDX60 YLPM1 NDST4 ABCF2 RAB39B RAB8A NOD2	2.93e-03	746	75	9	3.40.50.300
Domain	PDZ	RAPGEF6 RAPGEF2 NOS1 PREX2	2.98e-03	148	75	4	SM00228
Domain	-	RAPGEF6 RAPGEF2 NOS1 PREX2	3.12e-03	150	75	4	2.30.42.10
Domain	RasGEF_N	RAPGEF6 RAPGEF2	3.18e-03	21	75	2	PF00618
Domain	PDZ	RAPGEF6 RAPGEF2 NOS1 PREX2	3.20e-03	151	75	4	PS50106
Domain	PDZ	RAPGEF6 RAPGEF2 NOS1 PREX2	3.27e-03	152	75	4	IPR001478
Domain	Ras-like_Gua-exchang_fac_N	RAPGEF6 RAPGEF2	3.49e-03	22	75	2	IPR000651
Domain	SEA	TMPRSS15 ADGRF1	3.49e-03	22	75	2	PF01390
Domain	RASGEF_NTER	RAPGEF6 RAPGEF2	3.49e-03	22	75	2	PS50212
Domain	Spectrin	SYNE3 SPTBN2	3.81e-03	23	75	2	PF00435
Domain	SEA	TMPRSS15 ADGRF1	3.81e-03	23	75	2	PS50024
Domain	SEA_dom	TMPRSS15 ADGRF1	3.81e-03	23	75	2	IPR000082
Pubmed	Leukotriene B4 Enhances NOD2-Dependent Innate Response against Influenza Virus Infection.	MAVS NOD2	4.97e-06	2	78	2	26444420
Pubmed	CRTR-1, a developmentally regulated transcriptional repressor related to the CP2 family of transcription factors.	TFCP2L1 TFCP2	4.97e-06	2	78	2	11073954
Pubmed	The PDZ domain of the guanine nucleotide exchange factor PDZGEF directs binding to phosphatidic acid during brush border formation.	RAPGEF6 RAPGEF2	4.97e-06	2	78	2	24858808
Pubmed	Nod2 is essential for temporal development of intestinal microbial communities.	MAVS NOD2	4.97e-06	2	78	2	21421666
Pubmed	Gene networks associated with conditional fear in mice identified using a systems genetics approach.	TYR GRM5	4.97e-06	2	78	2	21410935
Pubmed	DDX60 Is Involved in RIG-I-Dependent and Independent Antiviral Responses, and Its Function Is Attenuated by Virus-Induced EGFR Activation.	MAVS DDX60	4.97e-06	2	78	2	25981042
Pubmed	Modulation of CP2 family transcriptional activity by CRTR-1 and sumoylation.	TFCP2L1 TFCP2	4.97e-06	2	78	2	20661472
Pubmed	Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice.	SLC6A2 RICTOR	4.97e-06	2	78	2	20543991
Pubmed	Phosphatidic acid-dependent localization and basal de-phosphorylation of RA-GEFs regulate lymphocyte trafficking.	RAPGEF6 RAPGEF2	4.97e-06	2	78	2	32600317
Pubmed	Genetic susceptibility factors in a cohort of 38 patients with SAPHO syndrome: a study of PSTPIP2, NOD2, and LPIN2 genes.	PSTPIP2 NOD2	1.49e-05	3	78	2	20032092
Pubmed	TFCP2/TFCP2L1/UBP1 transcription factors in cancer.	TFCP2L1 TFCP2	1.49e-05	3	78	2	29410248
Pubmed	Comprehensive behavioral analysis of mice deficient in Rapgef2 and Rapgef6, a subfamily of guanine nucleotide exchange factors for Rap small GTPases possessing the Ras/Rap-associating domain.	RAPGEF6 RAPGEF2	1.49e-05	3	78	2	29747665
Pubmed	NOD2, the gene responsible for familial granulomatous uveitis, in a mouse model of uveitis.	TYR NOD2	1.49e-05	3	78	2	18385071
Pubmed	Mouse superkiller-2-like helicase DDX60 is dispensable for type I IFN induction and immunity to multiple viruses.	MAVS DDX60	1.49e-05	3	78	2	26457795
Pubmed	Activation of innate immune antiviral responses by Nod2.	MAVS NOD2	1.49e-05	3	78	2	19701189
Pubmed	Vacuolar H+-ATPase d2 subunit: molecular characterization, developmental regulation, and localization to specialized proton pumps in kidney and bone.	ATP6V0A4 TCIRG1	1.49e-05	3	78	2	15800125
Pubmed	The function of vacuolar ATPase (V-ATPase) a subunit isoforms in invasiveness of MCF10a and MCF10CA1a human breast cancer cells.	ATP6V0A4 TCIRG1	1.49e-05	3	78	2	24072707
Pubmed	Anterograde trafficking of KCa3.1 in polarized epithelia is Rab1- and Rab8-dependent and recycling endosome-independent.	KCNN4 RAB8A	1.49e-05	3	78	2	24632741
Pubmed	PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.	RAPGEF6 RBM27 YLPM1 MTMR3 TFCP2 SLC3A2	2.02e-05	247	78	6	32989298
Pubmed	Lowered expression of heparan sulfate/heparin biosynthesis enzyme N-deacetylase/n-sulfotransferase 1 results in increased sulfation of mast cell heparin.	NDST1 NDST4	2.97e-05	4	78	2	22049073
Pubmed	Regulated translation of heparan sulfate N-acetylglucosamine N-deacetylase/n-sulfotransferase isozymes by structured 5'-untranslated regions and internal ribosome entry sites.	NDST1 NDST4	2.97e-05	4	78	2	12070138
Pubmed	Role of the NFKB1 -94ins/delATTG promoter polymorphism in IBD and potential interactions with polymorphisms in the CARD15/NOD2, IKBL, and IL-1RN genes.	NFKBIL1 NOD2	2.97e-05	4	78	2	16804398
Pubmed	Nucleotide oligomerization domain-2 (NOD2)-induced uveitis: dependence on IFN-gamma.	TYR NOD2	2.97e-05	4	78	2	19098321
Pubmed	Differential localization of vacuolar H+-ATPases containing a1, a2, a3, or a4 (ATP6V0A1-4) subunit isoforms along the nephron.	ATP6V0A4 TCIRG1	2.97e-05	4	78	2	17595521
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	RAPGEF6 RBM27 RABEP1 AHCTF1 SPTBN2 YLPM1 KDM1A SLC3A2	3.26e-05	549	78	8	38280479
Pubmed	Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism.	RABEP1 PKD1	4.94e-05	5	78	2	25405894
Pubmed	The a subunit isoforms of vacuolar-type proton ATPase exhibit differential distribution in mouse perigastrulation embryos.	ATP6V0A4 TCIRG1	4.94e-05	5	78	2	35948619
Pubmed	Induction of type I interferon signaling determines the relative pathogenicity of Staphylococcus aureus strains.	MAVS NOD2	4.94e-05	5	78	2	24586160
Pubmed	a4, a unique kidney-specific isoform of mouse vacuolar H+-ATPase subunit a.	ATP6V0A4 TCIRG1	4.94e-05	5	78	2	11498539
Pubmed	Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4.	NDST1 NDST4	4.94e-05	5	78	2	11087757
Pubmed	Aldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution.	ATP6V0A4 TCIRG1	7.40e-05	6	78	2	21307348
Pubmed	Identification and characterization of Grainyhead-like epithelial transactivator (GET-1), a novel mammalian Grainyhead-like factor.	TFCP2L1 TFCP2	7.40e-05	6	78	2	12666198
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SPTBN2 MTMR3 RAPGEF2 KDM6B	9.08e-05	104	78	4	9205841
Pubmed	Optic nerve compression and retinal degeneration in Tcirg1 mutant mice lacking the vacuolar-type H-ATPase a3 subunit.	ATP6V0A4 TCIRG1	1.04e-04	7	78	2	20711468
Pubmed	Streptococcus pneumoniae stimulates a STING- and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs.	MAVS NOD2	1.04e-04	7	78	2	22156592
Pubmed	P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration.	RICTOR PREX2	1.04e-04	7	78	2	17565979
Pubmed	Transient pluripotent cell populations during primitive ectoderm formation: correlation of in vivo and in vitro pluripotent cell development.	TFCP2L1 RBM27	1.04e-04	7	78	2	11839785
Pubmed	Addendum: defective Dock2 expression in a subset of ASC-deficient mouse lines.	MAVS NOD2	1.04e-04	7	78	2	22905357
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	SPTBN2 ATP6V0A4 RTTN TCF25 SLC3A2 COX14 SH3BP4	1.27e-04	496	78	7	31343991
Pubmed	FGF signaling sustains the odontogenic fate of dental mesenchyme by suppressing β-catenin signaling.	NDST1 NDST4	1.38e-04	8	78	2	24067353
Pubmed	Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior.	GRM5 NOS1	1.38e-04	8	78	2	18606955
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NDST1 ARHGEF40 RAPGEF6 SYNE3 RTTN PKD1 MTMR3 KDM6B SH3BP4 NOD2	1.79e-04	1105	78	10	35748872
Pubmed	Dependence of serotonergic and other nonadrenergic enteric neurons on norepinephrine transporter expression.	SLC6A2 NOS1	2.21e-04	10	78	2	21148012
Pubmed	JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function.	RAPGEF6 RAPGEF2	2.21e-04	10	78	2	23885123
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	RAPGEF6 MAVS RBM27 RABEP1 AHCTF1 YLPM1 LTA4H TFCP2 SLC3A2	2.43e-04	934	78	9	33916271
Pubmed	Developmental and regional expression of heparan sulfate sulfotransferase genes in the mouse brain.	NDST1 NDST4	2.70e-04	11	78	2	15944372
Pubmed	Genome-wide association study of tanning phenotype in a population of European ancestry.	TYR GRM5	2.70e-04	11	78	2	19340012
Pubmed	JMJD3 promotes chondrocyte proliferation and hypertrophy during endochondral bone formation in mice.	KDM6B MMP13	2.70e-04	11	78	2	25587042
Pubmed	Rab27a regulates the peripheral distribution of melanosomes in melanocytes.	TYR RAB8A	2.70e-04	11	78	2	11266470
Pubmed	Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling.	NDST1 NDST4	3.23e-04	12	78	2	12460940
Pubmed	Crucial Role of Rapgef2 and Rapgef6, a Family of Guanine Nucleotide Exchange Factors for Rap1 Small GTPase, in Formation of Apical Surface Adherens Junctions and Neural Progenitor Development in the Mouse Cerebral Cortex.	RAPGEF6 RAPGEF2	3.81e-04	13	78	2	27390776
Pubmed	A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP.	MAVS NOD2	3.81e-04	13	78	2	19652017
Pubmed	Genetic, physical, and transcript map of the Ltxs1 region of mouse chromosome 11.	RABEP1 PLD2	3.81e-04	13	78	2	11318612
Pubmed	Structure and Roles of V-type ATPases.	ATP6V0A4 TCIRG1	3.81e-04	13	78	2	32001091
Pubmed	Identification and characterization of multiple novel Rab-myosin Va interactions.	RAB39B RAB8A	4.44e-04	14	78	2	24006491
Pubmed	CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction†.	ALLC IQCA1	4.44e-04	14	78	2	32588039
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	IGFALS AHCTF1 ATP6V0A4 PKD1 LTA4H ENPEP SLC3A2 RAB8A SH3BP4	4.49e-04	1016	78	9	19056867
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	RAPGEF6 RABEP1 MTMR3 RICTOR RAPGEF2 RAB8A	5.07e-04	446	78	6	24255178
Pubmed	Rap2A links intestinal cell polarity to brush border formation.	RAPGEF6 RAPGEF2	5.12e-04	15	78	2	22797597
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	ARHGEF40 RAPGEF6 TRAM1 TCF25 RICTOR LRRC41 SH3BP4	6.47e-04	650	78	7	38777146
Pubmed	Ciliopathy-associated gene Cc2d2a promotes assembly of subdistal appendages on the mother centriole during cilia biogenesis.	CC2D2A RAB8A	6.61e-04	17	78	2	24947469
Pubmed	Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.	ATP6V0A4 TCIRG1	6.61e-04	17	78	2	33065002
Pubmed	Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.	TFCP2L1 LTA4H TFCP2 KDM1A	6.90e-04	177	78	4	26206133
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	RBM27 AHCTF1 YLPM1 SH3BP4	7.34e-04	180	78	4	35198878
Pubmed	Introduction: V-ATPases 1992-1998.	ATP6V0A4 TCIRG1	7.42e-04	18	78	2	10340843
Pubmed	Animal plasma membrane energization by proton-motive V-ATPases.	ATP6V0A4 TCIRG1	7.42e-04	18	78	2	10440860
Pubmed	Role of Ostm1 Cytosolic Complex with Kinesin 5B in Intracellular Dispersion and Trafficking.	MTMR3 LRRC41	7.42e-04	18	78	2	26598607
Pubmed	The vacuolar H+-ATPase: a universal proton pump of eukaryotes.	ATP6V0A4 TCIRG1	7.42e-04	18	78	2	9210392
Pubmed	Vacuolar and plasma membrane proton-adenosinetriphosphatases.	ATP6V0A4 TCIRG1	7.42e-04	18	78	2	10221984
Pubmed	Structure and properties of the vacuolar (H+)-ATPases.	ATP6V0A4 TCIRG1	7.42e-04	18	78	2	10224039
Pubmed	The G protein-coupled receptor repertoires of human and mouse.	GPR137C GRM5 ADGRF1	7.59e-04	79	78	3	12679517
Pubmed	Structure, function and regulation of the vacuolar (H+)-ATPase.	ATP6V0A4 TCIRG1	8.28e-04	19	78	2	9442887
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ARHGEF40 AHCTF1 NFKBIL1 TCF25 ECT2L RICTOR RAPGEF2 KDM1A LRRC41	8.76e-04	1116	78	9	31753913
Pubmed	The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development.	KDM6B NOS1	9.19e-04	20	78	2	35177643
Pubmed	Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development.	NDST1 NDST4	9.19e-04	20	78	2	17107998
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KDM6B KDM1A	1.01e-03	21	78	2	27626377
Pubmed	The vacuolar (H+)-ATPases--nature's most versatile proton pumps.	ATP6V0A4 TCIRG1	1.11e-03	22	78	2	11836511
Pubmed	Proton translocation driven by ATP hydrolysis in V-ATPases.	ATP6V0A4 TCIRG1	1.11e-03	22	78	2	12788495
Pubmed	Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes.	ATP6V0A4 TCIRG1	1.11e-03	22	78	2	14580332
Pubmed	Neurotransmitter release: the dark side of the vacuolar-H+ATPase.	ATP6V0A4 TCIRG1	1.11e-03	22	78	2	14597263
Pubmed	NDST1-dependent heparan sulfate regulates BMP signaling and internalization in lung development.	NDST1 NDST4	1.11e-03	22	78	2	19299468
Pubmed	Coupling of rotation and catalysis in F(1)-ATPase revealed by single-molecule imaging and manipulation.	ATP6V0A4 TCIRG1	1.11e-03	22	78	2	17662945
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	ARHGEF40 DDX60 UTP20 RICTOR	1.13e-03	202	78	4	33005030
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	RIOX2 RBM27 DDX60 YLPM1 ABCF2 PSTPIP2 TFCP2	1.21e-03	724	78	7	36232890
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	RIOX2 AHCTF1 SPTBN2 TCF25 UTP20 ABCF2 SLC3A2 RAB8A	1.30e-03	949	78	8	36574265
Pubmed	Grainyhead-related transcription factor is required for duct maturation in the salivary gland and the kidney of the mouse.	TFCP2L1 NOS1	1.33e-03	24	78	2	17079272
Pubmed	Mitochondrial antiviral-signalling protein is a client of the BAG6 protein quality control complex.	MAVS RBM27	1.33e-03	24	78	2	35543156
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SPTBN2 BIVM YLPM1 CC2D2A ABCF2 ATP10B RAB39B BTNL9 SLC3A2 RAB8A	1.41e-03	1442	78	10	35575683
Pubmed	Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor.	ATP6V0A4 TCIRG1	1.44e-03	25	78	2	2874839
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	NDST1 PKD1 CC2D2A	1.50e-03	100	78	3	25807483
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	MAVS RBM27 AHCTF1 TMEM131L SLC3A2 RAB8A	1.76e-03	568	78	6	37774976
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SYNE3 TRAM1 AHCTF1 SPTBN2 TMEM131L RICTOR TFCP2 SLC3A2 LRRC41 SH3BP4	1.77e-03	1487	78	10	33957083
Pubmed	Genetic link between renal birth defects and congenital heart disease.	PKD1 CC2D2A	1.81e-03	28	78	2	27002738
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	RIOX2 RBM27 TRAM1 AHCTF1 UTP20 ABCF2 ECT2L RICTOR KDM1A SLC3A2	1.86e-03	1497	78	10	31527615
Pubmed	A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.	TRAM1 ATP6V0A4 TCIRG1 RICTOR SLC3A2	1.91e-03	392	78	5	33144569
Pubmed	Motor neuron position and topographic order imposed by β- and γ-catenin activities.	NOS1 CDH9	1.94e-03	29	78	2	22036570
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	AHCTF1 ABCF2 KDM1A RAB8A	2.02e-03	237	78	4	29564676
Pubmed	Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.	RABEP1 YLPM1 KDM1A	2.02e-03	111	78	3	22558309
GeneFamily	Butyrophilins\|V-set domain containing\|C2-set domain containing	BTN2A3P BTNL9	7.69e-04	15	50	2	458
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF40 ECT2L PREX2	8.06e-04	66	50	3	722
GeneFamily	PDZ domain containing	RAPGEF6 RAPGEF2 NOS1 PREX2	8.19e-04	152	50	4	1220
GeneFamily	V-type ATPases	ATP6V0A4 TCIRG1	1.83e-03	23	50	2	415
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM6B KDM1A	1.99e-03	24	50	2	485
GeneFamily	WD repeat domain containing\|Caspase recruitment domain containing\|Apoptosome	MAVS NOD2	3.10e-03	30	50	2	959
GeneFamily	Sulfotransferases, membrane bound	NDST1 NDST4	4.69e-03	37	50	2	763
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	YLPM1 GRM5 PREX2	1.37e-02	181	50	3	694
GeneFamily	RAB, member RAS oncogene GTPases	RAB39B RAB8A	1.40e-02	65	50	2	388
Coexpression	GSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_UP	OGFRL1 RAPGEF6 RBM27 MYO9A UNC13D RICTOR PRIMPOL	2.19e-06	199	78	7	M6443
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 PSMG4 LRRC9	2.50e-08	175	78	7	98947a226b5a2ac7091ff9d34243ea7736add973
ToppCell	COVID-19-kidney-CD-IC-A\|kidney / Disease (COVID-19 only), tissue and cell type	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 PSMG4 SH3BP4	3.40e-08	183	78	7	5c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 SH3BP4	2.62e-07	150	78	6	87968ce885a4959616f0321f58517fe8029ba1b1
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 LRRC9	3.83e-07	160	78	6	174a4ab27114efcc63be36929b80680be3c35c9b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 LRRC9	4.42e-07	164	78	6	83141be8dfed85511ea6afda7c76ff4b6b5ef021
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 LRRC9	4.58e-07	165	78	6	9bd332e5ede759a00a47728ea5558c215efdd77a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 LRRC9	5.28e-07	169	78	6	4b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 LRRC9	5.28e-07	169	78	6	a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 LRRC9	6.05e-07	173	78	6	0bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 ATP6V0A4 ADGRF1 VWA5B1 SH3BP4 LRRC9	6.47e-07	175	78	6	77c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 LRRC9	6.69e-07	176	78	6	25ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCell	COVID-19-kidney-CD-IC-A\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 PSMG4	6.69e-07	176	78	6	45028197364c64e93e3ffe86aff773d47a477d49
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 LRRC9	6.92e-07	177	78	6	8e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 LRRC9	6.92e-07	177	78	6	f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 SH3BP4	9.24e-07	186	78	6	a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 SH3BP4	9.83e-07	188	78	6	e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 LRRC9	2.64e-06	124	78	5	1fec6663cea40017438ead397b3bf8b3cdb67e58
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC6A2 TFCP2L1 ATP6V0A4 VWA5B1 COX14	4.14e-06	136	78	5	7cd22169fb71c6caf9feb203ad98be8480a54fba
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 LRRC9	5.86e-06	146	78	5	e887e9de895fd453faa703997ef372cc6410fc49
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 ATP6V0A4 ADGRF1 VWA5B1 PSMG4	8.34e-06	157	78	5	c17c5c01fcb65c453690c265ec4f300ecdfefd34
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1	8.60e-06	158	78	5	debebc8534a80e5500051f6fd352dc201585968d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 LRRC9	1.03e-05	164	78	5	d847d509bb1791638032ade6755d8164586b5bd5
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 LRRC9	1.06e-05	165	78	5	a6c6de17fec678ad0cac3138dde3a14cc39ffd26
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 LRRC9	1.09e-05	166	78	5	6fe8db8d45177a78605681f22e04fa8d0594f2df
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 ATP6V0A4 ADGRF1 VWA5B1 SH3BP4	1.13e-05	167	78	5	edc5f04584b44f99ff9a62bbe0dab6fc044fb334
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 ATP6V0A4 ADGRF1 VWA5B1 LRRC9	1.19e-05	169	78	5	2a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCell	Ionocyte-iono-2\|World / Class top	SLC6A2 OGFRL1 NDST1 TFCP2L1 SH3BP4	1.33e-05	173	78	5	e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 ATP6V0A4 ADGRF1 VWA5B1 LRRC9	1.37e-05	174	78	5	5f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1	1.41e-05	175	78	5	1d8da48236549c01381f777ce5b2937f9f86acc2
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 ATP6V0A4 ADGRF1 VWA5B1 SH3BP4	1.57e-05	179	78	5	e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1	1.57e-05	179	78	5	27ad6a609fe1f7532b142d0147bccf918704a6dd
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 ATP6V0A4 ADGRF1 VWA5B1 SH3BP4	1.66e-05	181	78	5	30729f0364f719c044712a51453e22dc2c1a232b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1	1.84e-05	185	78	5	3d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1	1.94e-05	187	78	5	2d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCell	COVID-19-Epithelial-Ionocytes\|COVID-19 / Condition, Lineage and Cell class	TFCP2L1 PDGFD SPTBN2 ATP6V0A4 ADGRF1	1.99e-05	188	78	5	a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1	2.04e-05	189	78	5	a9864873b19ab3e60acf11f288fa7275badc2e42
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 VWA5B1	2.04e-05	189	78	5	532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1 SH3BP4	2.20e-05	192	78	5	f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TFCP2L1 SPTBN2 ATP6V0A4 ATP10B ADGRF1	2.49e-05	197	78	5	5c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCell	10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-MPP_myeloid\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CEMP1 ENPEP CDH9 PREX2	1.07e-04	140	78	4	eb1d22f5f5dbf60b6485464baec4be9b3060f65c
ToppCell	TCGA-Uvea\|World / Sample_Type by Project: Shred V9	TYR CEMP1 RTTN SLC3A2	1.10e-04	141	78	4	015451a83087f2705d3315ebc8f23797c6f10ed6
ToppCell	Goblet-gob-2\|World / Class top	TFCP2L1 KCNN4 ATP10B ENPEP	1.13e-04	142	78	4	9b058dc313d1f0edcd8473e342852632e17536a6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 ATP6V0A4 ADGRF1 VWA5B1	1.19e-04	144	78	4	cc11cce43d1af8ac63140d05faf215ae9a10cde1
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TYR ARHGEF40 DPP3 BTNL9	1.29e-04	147	78	4	c8e5bdc3538089acd35a4b41390afaec0ac6d1aa
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 VWA5B1	1.62e-04	156	78	4	a4b0e89255ea5d60198cb2b3e739981f9c9cf5c5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 ATP6V0A4 ADGRF1 VWA5B1	1.79e-04	160	78	4	1e210e526ea4d84fc58a798a26c0929bcb69fd89
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4\|Lung / Manually curated celltypes from each tissue	RAPGEF6 IQCA1 ECT2L ADGRF1	1.88e-04	162	78	4	91cc14aec8d580cf97a1929bc1acb00fcbcdb57a
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	OGFRL1 LRP12 NDST4 NOS1	1.97e-04	164	78	4	08819970174a3eb4eee8e1e675075828665b845e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE3 PDGFD NOS1 PREX2	2.01e-04	165	78	4	a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC6A2 TFCP2L1 ATP6V0A4 VWA5B1	2.01e-04	165	78	4	dc570154baed59ed109e5369589448e075ba66a9
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	IQCA1 ATP6V0A4 SH3BP4	2.03e-04	65	78	3	f14b28214f80ed23501ab28ff254c206f70d77b2
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L6_SST_NPY_(Sst_Chodl)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NDST4 IGSF9 BTNL9 NOS1	2.11e-04	167	78	4	de3ce3cf2815b0ad97755b71bb4505c3a2d1daa1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE3 PDGFD NOS1 PREX2	2.21e-04	169	78	4	c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell	NS-critical-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RIOX2 TFCP2L1 IGSF9 SH3BP4	2.21e-04	169	78	4	aec97583b23112060437b619cb429dc32f29285f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTX4 IQCA1 VWA5B1 LRRC9	2.26e-04	170	78	4	b535baeb4dbd644051cf992babb61add9eaae4e3
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTX4 IQCA1 VWA5B1 LRRC9	2.26e-04	170	78	4	2477c9f29dbe27f172df699003971e828d6ab8c9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1	2.26e-04	170	78	4	3229f2a02bfa075aa61118552d0407fc018ab3d1
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC6A2 KCNN4 ADGRF1 VWA5B1	2.31e-04	171	78	4	59b9dbaa05b6e5740edc633c9ce1181565550d5b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC6A2 KCNN4 ADGRF1 VWA5B1	2.31e-04	171	78	4	a5b9dd2b6a54db7962beeb5a9ceb9dacfb613fa7
ToppCell	TCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-5\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	ATP6V0A4 ECT2L GRM5 ADGRF1	2.36e-04	172	78	4	6b8a8d3b97c10b9d092307eed3cacbd2745df185
ToppCell	Bronchial_Brush-Epithelial-Ionocytes\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	TFCP2L1 PDGFD NDST4 RAB39B	2.41e-04	173	78	4	e1de849dcd96063136bdac87e050ddbd55cabdcc
ToppCell	Bronchial_Brush-Epithelial-Ionocytes\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	TFCP2L1 PDGFD NDST4 RAB39B	2.41e-04	173	78	4	f2a8f4918c1fb68d98bc3f33cd624de0f0f11e06
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 ATP6V0A4 ADGRF1 VWA5B1	2.58e-04	176	78	4	c2c4306476989bc2fb30dab00250ef7915842f13
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 ATP6V0A4 VWA5B1 LRRC9	2.58e-04	176	78	4	6c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDGFD KCNN4 BTNL9 PREX2	2.58e-04	176	78	4	27e6b3ae41068d6cfdda3d46da7df2a27567140e
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDGFD KCNN4 BTNL9 PREX2	2.58e-04	176	78	4	d6a5470af9592f34a741265f2ea9651c05c3add3
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BTNL9 NOS1 PREX2 SH3BP4	2.63e-04	177	78	4	5ff8dcfb030312126695d53a026d2e104a401b83
ToppCell	facs-Marrow-Granulocytes-24m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TFCP2L1 ARHGEF40 SPTBN2 ADGRF1	2.63e-04	177	78	4	4a697866ed542d3201714234cee03451adf1dcc9
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_prolif-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KCNN4 TCIRG1 UNC13D NOD2	2.69e-04	178	78	4	30d2b54462fd16222ad2e3806be6143e834b29e0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IQCA1 MYO9A ATP10B GRM5	2.87e-04	181	78	4	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	COVID-19-kidney-CD-IC-B\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TFCP2L1 ATP6V0A4 ADGRF1 VWA5B1	2.93e-04	182	78	4	ee6a8c356bbbdae55e4ea858337e079491f9f4aa
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	RAPGEF6 YLPM1 UNC13D PSTPIP2	2.99e-04	183	78	4	310ad42b2b5d8ddd01d3a12db338f80ac1f5d08e
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RAPGEF6 YLPM1 UNC13D PSTPIP2	2.99e-04	183	78	4	fef51dcf180e6d4e136362c7e140ec5ef372e6d0
ToppCell	facs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	OGFRL1 ARHGEF40 TMEM131L IGSF9	3.11e-04	185	78	4	19fa853f6f746ccf232a343b3c9c7a5e55800409
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1	3.24e-04	187	78	4	7b0168bdaa7c6c6b39878aff6a17f0943189a380
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TFCP2L1 ATP6V0A4 ENPEP CDH9	3.24e-04	187	78	4	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	COVID-19-kidney-CD-IC-B\|kidney / Disease (COVID-19 only), tissue and cell type	TFCP2L1 ATP6V0A4 ADGRF1 VWA5B1	3.24e-04	187	78	4	ce05b89860573fe0356102e2998d1ef6d1968034
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	AHCTF1 TMEM131L RICTOR RAPGEF2	3.31e-04	188	78	4	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 ATP6V0A4 NOS1 SH3BP4	3.31e-04	188	78	4	bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 ATP6V0A4 NOS1 SH3BP4	3.31e-04	188	78	4	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 ATP6V0A4 ADGRF1 VWA5B1	3.31e-04	188	78	4	58ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE3 PDGFD BTNL9 PREX2	3.31e-04	188	78	4	c2c51c6526defe2600302901159b8abbb58d7595
ToppCell	COVID-19-kidney-CD-PC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1	3.31e-04	188	78	4	8f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 ATP6V0A4 ADGRF1 VWA5B1	3.44e-04	190	78	4	b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCell	COVID-19-Heart-EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	RAPGEF2 BTNL9 ENPEP PREX2	3.44e-04	190	78	4	a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_progenitor_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OGFRL1 IGFALS KCNN4 ATP10B	3.44e-04	190	78	4	0bad41d19dc515e6bc61e699f4d56664cf2e72fd
ToppCell	control-Myeloid-Neutrophils_1\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ARHGEF40 AHCTF1 RICTOR KDM6B	3.51e-04	191	78	4	db1b3cd07d7d190155b2d14e82e1d124975fbd0b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE3 PDGFD BTNL9 PREX2	3.51e-04	191	78	4	b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell	cellseq-Epithelial-Epithelial_Glandular-SMG_Basal/Duct\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TFCP2L1 KCNN4 ATP10B SH3BP4	3.51e-04	191	78	4	30e7cc5f7eadf90ab0900a73fdfe48f9a1adcbfb
ToppCell	Dendritic_Cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	OGFRL1 ARHGEF40 NFKBIL1 PSTPIP2	3.51e-04	191	78	4	b51c8ff1279581088557bb36760c70209c77148c
ToppCell	cellseq-Epithelial-Epithelial_Glandular-SMG_Basal/Duct-SMG_Basal/Duct\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TFCP2L1 KCNN4 ATP10B SH3BP4	3.51e-04	191	78	4	41d2f5278f6d5f52a5bdf4f3df70969481c00162
ToppCell	Basal_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	SLC6A2 KCNN4 IGSF9 MMP13	3.51e-04	191	78	4	a98915bad9a4a61dd4cbca798914849b805f4a19
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1	3.51e-04	191	78	4	feec8617678b778475747ad406c80231e07fd6f7
ToppCell	COVID-19-kidney-CNT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1	3.58e-04	192	78	4	760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TFCP2L1 SPTBN2 ATP6V0A4 ADGRF1	3.58e-04	192	78	4	40f44ac4ab673ee6156abdd2074a60b9de3281ad
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFD BTNL9 PREX2 NOD2	3.58e-04	192	78	4	8f20d3511dcb44445592b17d005a53da0052ae56
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial-endothelial_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFD BTNL9 PREX2 NOD2	3.58e-04	192	78	4	0986b7900021efe2a4df84a935e7c9a0af1b0e57
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFD BTNL9 PREX2 NOD2	3.58e-04	192	78	4	b28d294e42b303d1db6060231d84d7b9e4d9fccf
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE3 NDST4 NOS1 CDH9	3.65e-04	193	78	4	010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KCNN4 ADGRF1 VWA5B1 KDM1A	3.65e-04	193	78	4	a5695ce2e24a62026ae28f3dea07ca4a435206b8
Drug	methylhydroquinone	TYR LTA4H DDO NOD2	2.11e-06	27	78	4	CID000007253
Drug	Dihydroergocristine mesylate [24730-10-7]; Up 200; 5.6uM; MCF7; HT_HG-U133A	CEMP1 OGFRL1 IGFALS ABCF2 PLD2 KDM6B LRRC41	4.80e-06	195	78	7	7034_UP
Drug	Etomidate [33125-97-2]; Up 200; 16.4uM; MCF7; HT_HG-U133A	CEMP1 TMPRSS15 IQCA1 ATP10B DDO ADGRF1 TFCP2	5.30e-06	198	78	7	3519_UP
Drug	gly-asp	TYR TMPRSS15 DDO ENPEP	1.42e-05	43	78	4	CID000097363
Disease	autosomal recessive osteopetrosis 1 (implicated_via_orthology)	ATP6V0A4 TCIRG1	6.51e-05	5	76	2	DOID:0110942 (implicated_via_orthology)
Disease	platelet crit	ARHGEF40 RBM27 RTTN YLPM1 KCNN4 TMEM131L RICTOR PSTPIP2 KDM6B SH3BP4	1.62e-04	952	76	10	EFO_0007985
Disease	renal tubular acidosis (implicated_via_orthology)	ATP6V0A4 TCIRG1	1.81e-04	8	76	2	DOID:14219 (implicated_via_orthology)
Disease	endometriosis, unipolar depression	TYR CC2D2A GRM5	1.88e-04	43	76	3	EFO_0001065, EFO_0003761
Disease	hair colour measurement, eye colour measurement, skin pigmentation measurement	TYR GRM5	2.91e-04	10	76	2	EFO_0007009, EFO_0007822, EFO_0009764
Disease	Unipolar Depression	SLC6A2 GRM5 NOS1 ENPEP TFCP2	5.57e-04	259	76	5	C0041696
Disease	phosphatidylcholine 40:6 measurement	RAPGEF2 NOD2	8.68e-04	17	76	2	EFO_0010389
Disease	matrix metalloproteinase 12 measurement	PDGFD MMP13	9.75e-04	18	76	2	EFO_0010590
Disease	snoring measurement	TYR TRAM1 GRM5	1.35e-03	84	76	3	EFO_0008341
Disease	macula measurement	TYR MYO9A YLPM1 MTMR3	1.46e-03	189	76	4	EFO_0008375
Disease	red blood cell density measurement	TFCP2L1 ARHGEF40 MYO9A RABEP1 KCNN4 CC2D2A RICTOR KDM6B	1.91e-03	880	76	8	EFO_0007978
Disease	azoospermia (implicated_via_orthology)	NDST1 NDST4	2.20e-03	27	76	2	DOID:14227 (implicated_via_orthology)
Disease	neurotic disorder	YLPM1 GRM5 NOS1	2.28e-03	101	76	3	EFO_0004257
Disease	Bell's palsy	SLC6A2 RBM27 CC2D2A	2.35e-03	102	76	3	EFO_0007167

Protein segments in the cluster

Peptide	Gene	Start	Entry
WRRTFLHAANVVLDQ	BTN2A3P	291	Q96KV6
HDFRLIQQVAQEIWV	ABCF2	571	Q9UG63
EIRWFRSQTFNVVHL	BTNL9	71	Q6UXG8
HYFQWRRAQRQAAEE	COX14	36	Q96I36
ALRLQRFFQQAHEWV	ARHGEF40	871	Q8TER5
WIHQFSNNRRSADQI	CARNMT1	256	Q8N4J0
NLAWHVIFALLNAFQ	ADGRF1	816	Q5T601
NYFLVNSQQRWTHIR	ALLC	151	Q8N6M5
LHCIIAFQRLNWQRF	BIVM	411	Q86UB2
LQRAFWLDVSHNRLE	IGFALS	481	P35858
RQLFQERVALISHWF	ECT2L	21	Q008S8
NLQDQIRHWFIECRN	IQCA1	296	Q86XH1
FLPRNLFEQFHRWAN	ATP10B	81	O94823
ITNRRSFQNVHEWLE	RAB39B	91	Q96DA2
VLNNRFIRVLWHREN	RBM27	661	Q9P2N5
CERINFFRNALWLHV	PSTPIP2	221	Q9H939
FFRNALWLHVNQLSQ	PSTPIP2	226	Q9H939
FDNIRNWIRNIEEHA	RAB8A	96	P61006
QFHLRLEQERTQWAQ	RABEP1	131	Q15276
IIWNQENYRLFVIFH	LRRC9	1036	Q6ZRR7
NFNAINNSEIRFRWL	LTA4H	526	P09960
VARAVNWQERFQHLN	OGFRL1	216	Q5TC84
QEFWQHRFQCRLEGF	GRM5	356	P41594
NIWNRIFNFARSRHS	LRP12	601	Q9Y561
NRDTLWHLFNTLQRR	MAVS	51	Q7Z434
SIGALNQVRFRHWFV	KCNN4	181	O15554
NNNGLVRFRIQSIWH	TMPRSS15	686	P98073
WSVVLFFRAQRLNQN	GPR137C	316	Q8N3F9
RIGRLQQAQLWNFHT	KDM6B	146	O15054
LRNIHTFEFWNLNLI	DDX60	356	Q8IY21
WRLHSQENTRIQLVF	PDGFD	81	Q9GZP0
RFFWRLHPQQVDAEL	MMP13	306	P45452
QFTRAQWFAIQHISL	RNASE3	31	P12724
IQRVLFGNNLNFWLH	NDST1	276	P52848
AFNWRQAHMQARFVI	DPP3	561	Q9NY33
QHRNTIREWFFNLLE	ENPEP	941	Q07075
VQQVRWHPDRFLQRF	NFKBIL1	336	Q9UBC1
IQRVLFGNNLNFWLH	NDST4	266	Q9H3R1
LRVLLRANVEFFNNW	RICTOR	736	Q6R327
FRSFWQQRQFDIQHK	NOS1	1261	P29475
QWFRETFNHLFAIAN	DDO	66	Q99489
RHFLNWALQQREENS	CEMP1	136	Q6PRD7
RQILDWHFANLEFAN	KDM1A	526	O60341
RVHFGQIFNLQIVNW	CC2D2A	706	Q9P2K1
HWDQNERFLVVLNFG	SLC3A2	556	P08195
EAWNFLRQHCNRLNI	AHCTF1	891	Q8WYP5
LWENIDVQDFIHRRL	CDH9	706	Q9ULB4
IWRLFHRQAQAFNFV	PRIMPOL	41	Q96LW4
FLQWLDCVHQLQRQF	MTMR3	476	Q13615
RDRLRFLQLHNWLDN	PKD1	3831	P98161
FLQLHNWLDNRSRAV	PKD1	3836	P98161
EQFRRFQEVTWTHLQ	PTX4	46	Q96A99
QERQLFLHLLEWFNF	RTTN	41	Q86VV8
VAQRDIRQFQLQHWL	SLC6A2	601	P23975
CQERLDHTNFRFLLW	UTP20	811	O75691
RIVLLWVNNHFNDFE	RAPGEF6	476	Q8TEU7
QFQSREDFRTAWLNH	SH3BP4	276	Q9P0V3
NSLIWIQDIRHFSQR	TMEM131L	311	A2VDJ0
ARLRNAAAVELWQHF	SYNE3	431	Q6ZMZ3
HLRLFQNWLDQDAVT	LRRC41	766	Q15345
NFSARLWEQLVHFHV	PSMG4	16	Q5JS54
QWLHRNRFSQFCRLF	TFCP2L1	316	Q9NZI6
RVVLLWVNNHFNDFE	RAPGEF2	331	Q9Y4G8
RLHLLWAAGQDFQEF	NOD2	311	Q9HC29
RIAARQHNVARLWDF	SPTBN2	501	O15020
QEAQQWLHRNRFSTF	TFCP2	331	Q12800
AFVDSIFEQWLRRHR	TYR	391	P14679
RWLDQIANAGVLFHF	PREX2	1306	Q70Z35
RFWFTHNVLFNVSNR	USP9Y	2086	O00507
WFQDNINVFHISRLQ	IGSF9	261	Q9P2J2
QFHQPQRFKDELWRI	RIOX2	136	Q8IUF8
LDAINDRVRHFDQFW	YLPM1	1931	P49750
AFLHALRLHWVEFQN	ATP6V0A4	801	Q9HBG4
INFQLRRWREHSAFQ	TRAM1	316	Q15629
PARDLARHFIQRWNF	PLD2	551	O14939
RDGVLALDNFHRWFQ	UNC13D	576	Q70J99
RLFQEWEAHRNLSQL	TCF25	401	Q9BQ70
AFLHALRLHWVEFQN	TCIRG1	796	Q13488
QLFVLLRHWDENLEF	VWA5B1	1196	Q5TIE3
LFDWIVFRINHALLN	MYO9A	506	B2RTY4
HLRQASVIIQRFWRN	MYO9A	1041	B2RTY4