Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	signaling receptor complex adaptor activity	SH2D3C SHANK3 GNB4 GNB1 GNB2 GNB3	3.91e-06	54	156	6	GO:0030159
GeneOntologyMolecularFunction	SUMO ligase activity	RGPD4 RANBP2 RGPD8 RGPD3	1.58e-05	20	156	4	GO:0061665
GeneOntologyMolecularFunction	peptidyl-prolyl cis-trans isomerase activity	RGPD4 RANBP2 RGPD8 PPIG RGPD3	4.35e-05	50	156	5	GO:0003755
GeneOntologyMolecularFunction	cis-trans isomerase activity	RGPD4 RANBP2 RGPD8 PPIG RGPD3	5.79e-05	53	156	5	GO:0016859
GeneOntologyMolecularFunction	signaling adaptor activity	SH2D3C SHANK3 GNB4 GNB1 GNB2 GNB3 NSMAF	6.99e-05	129	156	7	GO:0035591
GeneOntologyMolecularFunction	SUMO transferase activity	RGPD4 RANBP2 RGPD8 RGPD3	1.74e-04	36	156	4	GO:0019789
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF567 HSFX4 ZNF695 ZNF493 ZNF280D FOXP2 SREBF2 NPAS3 RFX6 ZNF510 GTF2IRD1 ZBTB7B RFX1 RFX3 ZBTB1 ZNF17 ZSCAN32 ZNF257 ZBTB10 HSFX3 NHLH2 ZNF766 ZNF860 ZNF443	4.09e-04	1459	156	24	GO:0000977
GeneOntologyMolecularFunction	GTPase binding	RGPD4 RANBP2 ABCA1 RGPD8 MYCBP2 RAPGEF4 RGPD3 GNB1 GNB2 GNB3	5.48e-04	360	156	10	GO:0051020
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RGPD4 RANBP2 RGPD8 MYCBP2 DOCK8 SH2D3C RAPGEF4 ARHGAP5 ARAP3 RGPD3 HERC1 RGPD5	6.50e-04	507	156	12	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RGPD4 RANBP2 RGPD8 MYCBP2 DOCK8 SH2D3C RAPGEF4 ARHGAP5 ARAP3 RGPD3 HERC1 RGPD5	6.50e-04	507	156	12	GO:0030695
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	DCAF6 DDX17 RAPSN ZNF493 SYNE1 SH2D3C RAPGEF4 SRCAP TRRAP SHANK3 SLC9A1 FBXO9 PKM GNB4 GNB1 GNB2 GNB3 FSCN1 RHNO1 NSMAF	7.26e-04	1160	156	20	GO:0030674
GeneOntologyBiologicalProcess	NLS-bearing protein import into nucleus	RGPD4 RANBP2 RGPD8 RGPD3 RGPD5	2.89e-07	20	152	5	GO:0006607
GeneOntologyBiologicalProcess	positive regulation of glucokinase activity	RGPD4 RANBP2 RGPD8 RGPD3	3.47e-07	9	152	4	GO:0033133
GeneOntologyBiologicalProcess	positive regulation of hexokinase activity	RGPD4 RANBP2 RGPD8 RGPD3	5.75e-07	10	152	4	GO:1903301
GeneOntologyBiologicalProcess	regulation of glucokinase activity	RGPD4 RANBP2 RGPD8 RGPD3	1.92e-06	13	152	4	GO:0033131
GeneOntologyBiologicalProcess	regulation of hexokinase activity	RGPD4 RANBP2 RGPD8 RGPD3	2.68e-06	14	152	4	GO:1903299
GeneOntologyBiologicalProcess	glycosaminoglycan catabolic process	PGLYRP1 IDUA CEMIP2 SLC9A1 GUSB	3.49e-06	32	152	5	GO:0006027
GeneOntologyBiologicalProcess	protein peptidyl-prolyl isomerization	RGPD4 RANBP2 RGPD8 PPIG RGPD3	8.39e-06	38	152	5	GO:0000413
GeneOntologyBiologicalProcess	aminoglycan catabolic process	PGLYRP1 IDUA CEMIP2 SLC9A1 GUSB	8.39e-06	38	152	5	GO:0006026
GeneOntologyBiologicalProcess	glycosaminoglycan metabolic process	PGLYRP1 IDUA CEMIP2 ITIH5 SLC9A1 GUSB CHSY3	3.22e-05	121	152	7	GO:0030203
GeneOntologyBiologicalProcess	peptidyl-proline modification	RGPD4 RANBP2 RGPD8 PPIG RGPD3	4.81e-05	54	152	5	GO:0018208
GeneOntologyBiologicalProcess	aminoglycan metabolic process	PGLYRP1 IDUA CEMIP2 ITIH5 SLC9A1 GUSB CHSY3	5.61e-05	132	152	7	GO:0006022
GeneOntologyBiologicalProcess	mucopolysaccharide metabolic process	IDUA CEMIP2 ITIH5 SLC9A1 GUSB CHSY3	9.78e-05	100	152	6	GO:1903510
GeneOntologyBiologicalProcess	hyaluronan metabolic process	CEMIP2 ITIH5 SLC9A1 GUSB	2.11e-04	40	152	4	GO:0030212
GeneOntologyCellularComponent	cytoplasmic periphery of the nuclear pore complex	RGPD4 RANBP2 RGPD8 RGPD3	1.74e-07	8	150	4	GO:1990723
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	RGPD4 RANBP2 RGPD8 RGPD3	5.17e-07	10	150	4	GO:0044614
GeneOntologyCellularComponent	annulate lamellae	RGPD4 RANBP2 RGPD8 RGPD3	2.41e-06	14	150	4	GO:0005642
GeneOntologyCellularComponent	nuclear pore nuclear basket	RGPD4 RANBP2 RGPD8 RGPD3	7.21e-06	18	150	4	GO:0044615
GeneOntologyCellularComponent	nuclear inclusion body	RGPD4 RANBP2 RGPD8 RGPD3	1.13e-05	20	150	4	GO:0042405
GeneOntologyCellularComponent	SUMO ligase complex	RGPD4 RANBP2 RGPD8 RGPD3	1.39e-05	21	150	4	GO:0106068
GeneOntologyCellularComponent	heterotrimeric G-protein complex	GNB4 GNB1 GNB2 GNB3	1.12e-04	35	150	4	GO:0005834
GeneOntologyCellularComponent	GTPase complex	GNB4 GNB1 GNB2 GNB3	2.10e-04	41	150	4	GO:1905360
GeneOntologyCellularComponent	extrinsic component of plasma membrane	DNAJC6 GNB4 GNB1 GNB2 GNB3 CDH5	4.69e-04	137	150	6	GO:0019897
GeneOntologyCellularComponent	extrinsic component of cytoplasmic side of plasma membrane	GNB4 GNB1 GNB2 GNB3	7.00e-04	56	150	4	GO:0031234
GeneOntologyCellularComponent	nuclear pore	RGPD4 RANBP2 RGPD8 RGPD3 RGPD5	8.11e-04	101	150	5	GO:0005643
GeneOntologyCellularComponent	microtubule minus-end	ASPM CAMSAP1	1.05e-03	7	150	2	GO:0036449
GeneOntologyCellularComponent	hippocampal mossy fiber to CA3 synapse	RAPGEF4 GRIK5 NECTIN1 LNX1	1.37e-03	67	150	4	GO:0098686
MousePheno	enlarged stomach	ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1 IL6ST	9.10e-06	33	122	5	MP:0003883
MousePheno	elevated level of mitotic sister chromatid exchange	RGPD4 RANBP2 RGPD8 RGPD3	9.27e-06	16	122	4	MP:0003701
MousePheno	abnormal blastocyst formation	RGPD4 RANBP2 RGPD8 SRCAP RGPD3	2.12e-05	39	122	5	MP:0012128
MousePheno	increased hepatocellular carcinoma incidence	RGPD4 RANBP2 RGPD8 GTF2IRD1 RGPD3 SMURF2	3.25e-05	70	122	6	MP:0003331
MousePheno	abnormal morula morphology	RGPD4 RANBP2 RGPD8 RGPD3	7.12e-05	26	122	4	MP:0012058
MousePheno	perinatal lethality	ABCA1 PSMF1 RAPSN FOXP2 MYCBP2 TMEM94 SYNE1 SH2D3C F2 RFX3 SHANK3 FGF18 GGCX MAP3K4 EFTUD2 ARHGAP5 GUSB ACAN GNB1 FSCN1 CAMSAP1 SUCO IL6ST	1.04e-04	1130	122	23	MP:0002081
MousePheno	decreased tumor latency	RGPD4 RANBP2 RGPD8 RGPD3	1.27e-04	30	122	4	MP:0010308
MousePheno	failure of blastocyst formation	RGPD4 RANBP2 RGPD8 RGPD3	1.45e-04	31	122	4	MP:0012129
Domain	Guanine_nucleotide-bd_bsu	GNB4 GNB1 GNB2 GNB3	2.04e-08	5	151	4	IPR016346
Domain	Ran_BP1	RGPD4 RANBP2 RGPD8 RGPD3 RGPD5	2.45e-08	12	151	5	PF00638
Domain	RANBD1	RGPD4 RANBP2 RGPD8 RGPD3 RGPD5	2.45e-08	12	151	5	PS50196
Domain	RanBD	RGPD4 RANBP2 RGPD8 RGPD3 RGPD5	3.95e-08	13	151	5	SM00160
Domain	Ran_bind_dom	RGPD4 RANBP2 RGPD8 RGPD3 RGPD5	3.95e-08	13	151	5	IPR000156
Domain	Gprotein_B	GNB4 GNB1 GNB2 GNB3	8.30e-07	10	151	4	IPR001632
Domain	Grip	RGPD4 RGPD8 RGPD3 RGPD5	1.30e-06	11	151	4	SM00755
Domain	GRIP	RGPD4 RGPD8 RGPD3 RGPD5	1.30e-06	11	151	4	PF01465
Domain	GRIP_dom	RGPD4 RGPD8 RGPD3 RGPD5	1.93e-06	12	151	4	IPR000237
Domain	GRIP	RGPD4 RGPD8 RGPD3 RGPD5	1.93e-06	12	151	4	PS50913
Domain	WD40	DCAF6 CORO2A DCAF12L2 LYST GNB4 HERC1 MAPKBP1 GNB1 GNB2 GNB3 NSMAF	8.56e-06	259	151	11	PF00400
Domain	WD40	DCAF6 CORO2A DCAF12L2 LYST GNB4 HERC1 MAPKBP1 GNB1 GNB2 GNB3 NSMAF	1.18e-05	268	151	11	SM00320
Domain	WD40_repeat	DCAF6 CORO2A DCAF12L2 LYST GNB4 HERC1 MAPKBP1 GNB1 GNB2 GNB3 NSMAF	1.36e-05	272	151	11	IPR001680
Domain	WD_REPEATS_1	DCAF6 CORO2A DCAF12L2 LYST GNB4 HERC1 MAPKBP1 GNB1 GNB2 GNB3 NSMAF	1.66e-05	278	151	11	PS00678
Domain	WD_REPEATS_2	DCAF6 CORO2A DCAF12L2 LYST GNB4 HERC1 MAPKBP1 GNB1 GNB2 GNB3 NSMAF	1.72e-05	279	151	11	PS50082
Domain	WD_REPEATS_REGION	DCAF6 CORO2A DCAF12L2 LYST GNB4 HERC1 MAPKBP1 GNB1 GNB2 GNB3 NSMAF	1.72e-05	279	151	11	PS50294
Domain	Rab_bind	RGPD4 RGPD8 RGPD3	1.77e-05	7	151	3	PF16704
Domain	GCC2_Rab_bind	RGPD4 RGPD8 RGPD3	1.77e-05	7	151	3	IPR032023
Domain	TPR-contain_dom	RGPD4 RANBP2 RAPSN RGPD8 FBXO9 RGPD3 VPS13A RGPD5	3.03e-05	150	151	8	IPR013026
Domain	WD40_repeat_dom	DCAF6 CORO2A DCAF12L2 LYST GNB4 HERC1 MAPKBP1 GNB1 GNB2 GNB3 NSMAF	3.06e-05	297	151	11	IPR017986
Domain	RFX_DNA_binding	RFX6 RFX1 RFX3	4.20e-05	9	151	3	PF02257
Domain	DNA-bd_RFX	RFX6 RFX1 RFX3	4.20e-05	9	151	3	IPR003150
Domain	RFX_DBD	RFX6 RFX1 RFX3	4.20e-05	9	151	3	PS51526
Domain	TPR_REGION	RGPD4 RANBP2 RAPSN RGPD8 FBXO9 RGPD3 VPS13A RGPD5	5.96e-05	165	151	8	PS50293
Domain	TPR	RGPD4 RANBP2 RAPSN RGPD8 FBXO9 RGPD3 VPS13A RGPD5	5.96e-05	165	151	8	PS50005
Domain	-	RGPD4 RGPD8 RGPD3	5.96e-05	10	151	3	1.10.220.60
Domain	-	DCAF6 CORO2A DCAF12L2 LYST GNB4 HERC1 MAPKBP1 GNB1 GNB2 GNB3 NSMAF	8.57e-05	333	151	11	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	DCAF6 CORO2A DCAF12L2 LYST GNB4 HERC1 MAPKBP1 GNB1 GNB2 GNB3 NSMAF	9.04e-05	335	151	11	IPR015943
Domain	ZINC_FINGER_C2H2_2	ZNF567 ZNF695 ZNF493 ZNF280D FOXP2 ZNF510 ZBTB7B ZBTB1 ZNF17 ZSCAN32 KIN ZNF257 ZBTB10 ZNF766 ZNF860 ZNF512 ZNF443	1.80e-04	775	151	17	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF567 ZNF695 ZNF493 ZNF280D FOXP2 ZNF510 ZBTB7B ZBTB1 ZNF17 ZSCAN32 KIN ZNF257 ZBTB10 ZNF766 ZNF860 ZNF512 ZNF443	1.86e-04	777	151	17	PS00028
Domain	RFX1_trans_act	RFX1 RFX3	1.94e-04	3	151	2	IPR007668
Domain	RFX1_trans_act	RFX1 RFX3	1.94e-04	3	151	2	PF04589
Domain	Znf_C2H2-like	ZNF567 ZNF695 ZNF493 ZNF280D FOXP2 ZNF510 ZBTB7B ZBTB1 ZNF17 ZSCAN32 KIN ZNF257 ZBTB10 ZNF766 ZNF860 ZNF512 ZNF443	2.47e-04	796	151	17	IPR015880
Domain	ZnF_C2H2	ZNF567 ZNF695 ZNF493 ZNF280D FOXP2 ZNF510 ZBTB7B ZBTB1 ZNF17 ZSCAN32 KIN ZNF257 ZBTB10 ZNF766 ZNF860 ZNF512 ZNF443	2.94e-04	808	151	17	SM00355
Domain	WD40_repeat_CS	CORO2A LYST GNB4 HERC1 GNB1 GNB2 GNB3	3.79e-04	164	151	7	IPR019775
Domain	zf-C2H2	ZNF567 ZNF695 ZNF493 ZNF280D ZNF510 ZBTB7B ZBTB1 ZNF17 ZSCAN32 ZNF257 ZBTB10 ZNF766 ZNF860 ZNF512 ZNF443	5.05e-04	693	151	15	PF00096
Domain	TPR-like_helical_dom	RGPD4 RANBP2 RAPSN RGPD8 TRRAP FBXO9 RGPD3 RGPD5	6.26e-04	233	151	8	IPR011990
Domain	Znf_C2H2	ZNF567 ZNF695 ZNF493 ZNF280D FOXP2 ZNF510 ZBTB7B ZBTB1 ZNF17 ZSCAN32 ZNF257 ZBTB10 ZNF766 ZNF860 ZNF512 ZNF443	8.22e-04	805	151	16	IPR007087
Domain	CAMSAP_CH	ASPM CAMSAP1	1.33e-03	7	151	2	PF11971
Domain	CAMSAP_CH	ASPM CAMSAP1	1.33e-03	7	151	2	IPR022613
Domain	PH-BEACH_dom	LYST NSMAF	1.76e-03	8	151	2	IPR023362
Domain	-	LYST NSMAF	1.76e-03	8	151	2	2.30.29.40
Domain	PH_BEACH	LYST NSMAF	1.76e-03	8	151	2	PS51783
Domain	Helicase_C	DDX17 DHX38 SRCAP SHPRH DDX21	1.77e-03	107	151	5	PF00271
Domain	HELICc	DDX17 DHX38 SRCAP SHPRH DDX21	1.77e-03	107	151	5	SM00490
Domain	Helicase_C	DDX17 DHX38 SRCAP SHPRH DDX21	1.85e-03	108	151	5	IPR001650
Domain	HELICASE_CTER	DDX17 DHX38 SRCAP SHPRH DDX21	1.92e-03	109	151	5	PS51194
Domain	HELICASE_ATP_BIND_1	DDX17 DHX38 SRCAP SHPRH DDX21	1.92e-03	109	151	5	PS51192
Domain	DEXDc	DDX17 DHX38 SRCAP SHPRH DDX21	1.92e-03	109	151	5	SM00487
Domain	Helicase_ATP-bd	DDX17 DHX38 SRCAP SHPRH DDX21	2.00e-03	110	151	5	IPR014001
Domain	BEACH	LYST NSMAF	2.25e-03	9	151	2	PS50197
Domain	Beach	LYST NSMAF	2.25e-03	9	151	2	PF02138
Domain	-	LYST NSMAF	2.25e-03	9	151	2	1.10.1540.10
Domain	Beach	LYST NSMAF	2.25e-03	9	151	2	SM01026
Domain	BEACH_dom	LYST NSMAF	2.25e-03	9	151	2	IPR000409
Domain	KRAB	ZNF567 ZNF695 ZNF510 ZNF17 ZSCAN32 ZNF257 ZNF766 ZNF860 ZNF443	2.57e-03	358	151	9	PS50805
Pathway	REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING	GRIK5 GNB4 GNB1 GNB2 GNB3	3.84e-06	30	114	5	M18193
Pathway	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS	F2 GNB4 GNB1 GNB2 GNB3	5.36e-06	32	114	5	M861
Pathway	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS	F2 GNB4 GNB1 GNB2 GNB3	5.36e-06	32	114	5	MM15148
Pathway	REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING	GRIK5 GNB4 GNB1 GNB2 GNB3	5.36e-06	32	114	5	MM15143
Pathway	REACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION	RAPGEF4 GNB4 GNB1 GNB2 GNB3	5.36e-06	32	114	5	MM14983
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	SCTR GNB4 GNB1 GNB2 GNB3	6.27e-06	33	114	5	MM15066
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	SCTR GNB4 GNB1 GNB2 GNB3	6.27e-06	33	114	5	M10322
Pathway	BIOCARTA_RANBP2_PATHWAY	RGPD4 RANBP2 RGPD8 RGPD3	1.14e-05	18	114	4	MM1549
Pathway	REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR	GNB4 GNB1 GNB2 GNB3	1.43e-05	19	114	4	MM15021
Pathway	REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR	GNB4 GNB1 GNB2 GNB3	1.43e-05	19	114	4	M926
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_CDC42	GNB4 GNB1 GNB2 GNB3	1.78e-05	20	114	4	MM15572
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_CDC42	GNB4 GNB1 GNB2 GNB3	1.78e-05	20	114	4	M27853
Pathway	REACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION	RAPGEF4 GNB4 GNB1 GNB2 GNB3	2.12e-05	42	114	5	M791
Pathway	REACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS	GNB4 GNB1 GNB2 GNB3	2.18e-05	21	114	4	M27409
Pathway	REACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS	GNB4 GNB1 GNB2 GNB3	2.18e-05	21	114	4	MM15159
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12	GNB4 GNB1 GNB2 GNB3	2.65e-05	22	114	4	MM15016
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12	GNB4 GNB1 GNB2 GNB3	2.65e-05	22	114	4	M841
Pathway	REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION	GNB4 GNB1 GNB2 GNB3	3.19e-05	23	114	4	MM15033
Pathway	KEGG_MEDICUS_REFERENCE_LPAR_GNB_G_RHO_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	3.19e-05	23	114	4	M47549
Pathway	REACTOME_G_PROTEIN_ACTIVATION	GNB4 GNB1 GNB2 GNB3	3.80e-05	24	114	4	M13115
Pathway	REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR	GNB4 GNB1 GNB2 GNB3	3.80e-05	24	114	4	MM15088
Pathway	REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR	GNB4 GNB1 GNB2 GNB3	3.80e-05	24	114	4	M18308
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	3.80e-05	24	114	4	M47460
Pathway	REACTOME_G_PROTEIN_ACTIVATION	GNB4 GNB1 GNB2 GNB3	3.80e-05	24	114	4	MM14794
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1	GNB4 GNB1 GNB2 GNB3	4.50e-05	25	114	4	MM15056
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1	GNB4 GNB1 GNB2 GNB3	4.50e-05	25	114	4	M811
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA	GNB4 GNB1 GNB2 GNB3	4.50e-05	25	114	4	M14301
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA	GNB4 GNB1 GNB2 GNB3	5.29e-05	26	114	4	MM15017
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	5.29e-05	26	114	4	M47561
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	5.29e-05	26	114	4	M47562
Pathway	KEGG_MEDICUS_REFERENCE_CCR5_GNB_G_PLCB_G_PKC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	5.29e-05	26	114	4	M47557
Pathway	KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_PI3K_AKT_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	5.29e-05	26	114	4	M47456
Pathway	REACTOME_COMPLEMENT_CASCADE	CFH CFHR1 CPN1 F2 C1R C8B	5.96e-05	84	114	6	MM14653
Pathway	KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_ERK_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	6.17e-05	27	114	4	M47454
Pathway	REACTOME_GPER1_SIGNALING	GNB4 GNB1 GNB2 GNB3	6.17e-05	27	114	4	MM15664
Pathway	REACTOME_METABOLISM_OF_CARBOHYDRATES	RGPD4 RANBP2 RGPD8 IDUA SLC9A1 GUSB ACAN RGPD3 PKM CHSY3	6.86e-05	271	114	10	MM15406
Pathway	REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION	GNB4 GNB1 GNB2 GNB3	7.15e-05	28	114	4	M10679
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_JNK_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	8.24e-05	29	114	4	M47466
Pathway	REACTOME_ACTIVATION_OF_G_PROTEIN_GATED_POTASSIUM_CHANNELS	GNB4 GNB1 GNB2 GNB3	9.45e-05	30	114	4	MM14542
Pathway	REACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS	GNB4 GNB1 GNB2 GNB3	1.08e-04	31	114	4	MM15094
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.08e-04	31	114	4	M47554
Pathway	KEGG_MEDICUS_REFERENCE_CCR_CXCR_GNB_G_PI3K_RAC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.08e-04	31	114	4	M47455
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_ERK_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.08e-04	31	114	4	M47459
Pathway	KEGG_MEDICUS_REFERENCE_CCR2_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.08e-04	31	114	4	M47540
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.08e-04	31	114	4	M47541
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	GNB4 GNB1 GNB2 GNB3 GABRA4	1.21e-04	60	114	5	MM15708
Pathway	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	SCTR GNB4 GNB1 GNB2 GNB3	1.21e-04	60	114	5	MM14964
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	GNB4 GNB1 GNB2 GNB3 GABRA4	1.21e-04	60	114	5	M976
Pathway	REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING	GNB4 GNB1 GNB2 GNB3	1.22e-04	32	114	4	M14309
Pathway	KEGG_MEDICUS_REFERENCE_GPCR_PI3K_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.22e-04	32	114	4	M47962
Pathway	REACTOME_REGULATION_OF_INSULIN_SECRETION	RAPGEF4 GNB4 GNB1 GNB2 GNB3	1.31e-04	61	114	5	MM15071
Pathway	REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING	GNB4 GNB1 GNB2 GNB3	1.39e-04	33	114	4	MM15027
Pathway	REACTOME_SIGNAL_AMPLIFICATION	GNB4 GNB1 GNB2 GNB3	1.39e-04	33	114	4	MM15020
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	GNB4 GNB1 GNB2 GNB3	1.39e-04	33	114	4	MM15058
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNB_G_RHO_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.39e-04	33	114	4	M47550
Pathway	REACTOME_SIGNAL_AMPLIFICATION	GNB4 GNB1 GNB2 GNB3	1.39e-04	33	114	4	M9379
Pathway	REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION	GNB4 GNB1 GNB2 GNB3	1.39e-04	33	114	4	M11575
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	GNB4 GNB1 GNB2 GNB3	1.75e-04	35	114	4	M1075
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	GNB4 GNB1 GNB2 GNB3	1.96e-04	36	114	4	MM14544
Pathway	REACTOME_COOPERATION_OF_PDCL_PHLP1_AND_TRIC_CCT_IN_G_PROTEIN_BETA_FOLDING	GNB4 GNB1 GNB2 GNB3	2.42e-04	38	114	4	M27656
Pathway	REACTOME_CHAPERONIN_MEDIATED_PROTEIN_FOLDING	GNB4 GNB1 GNB2 GNB3	2.68e-04	39	114	4	MM15003
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	RAPGEF4 GNB4 GNB1 GNB2 GNB3	2.88e-04	72	114	5	MM14631
Pathway	REACTOME_AQUAPORIN_MEDIATED_TRANSPORT	GNB4 GNB1 GNB2 GNB3	2.96e-04	40	114	4	MM15115
Pathway	REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY	RGPD4 RANBP2 RGPD8 RGPD3	2.96e-04	40	114	4	MM14945
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS	RGPD4 RANBP2 RGPD8 RGPD3	3.26e-04	41	114	4	MM15200
Pathway	REACTOME_COMPLEMENT_CASCADE	CFH CFHR1 CPN1 F2 C1R C8B	3.37e-04	115	114	6	M19752
Pathway	REACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS	RGPD4 RANBP2 RGPD8 RGPD3	3.58e-04	42	114	4	MM15039
Pathway	REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA	RGPD4 RANBP2 RGPD8 RGPD3	3.93e-04	43	114	4	MM14609
Pathway	REACTOME_ADORA2B_MEDIATED_ANTI_INFLAMMATORY_CYTOKINES_PRODUCTION	GNB4 GNB1 GNB2 GNB3	3.93e-04	43	114	4	M29837
Pathway	REACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS	GNB4 GNB1 GNB2 GNB3	3.93e-04	43	114	4	M933
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	GNB4 GNB1 GNB2 GNB3	3.93e-04	43	114	4	M954
Pathway	REACTOME_REGULATION_OF_INSULIN_SECRETION	RAPGEF4 GNB4 GNB1 GNB2 GNB3	4.18e-04	78	114	5	M1921
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	GNB4 GNB1 GNB2 GNB3	4.29e-04	44	114	4	MM15709
Pathway	REACTOME_CA2_PATHWAY	GNB4 GNB1 GNB2 GNB3	4.68e-04	45	114	4	MM15040
Pathway	REACTOME_GPER1_SIGNALING	GNB4 GNB1 GNB2 GNB3	4.68e-04	45	114	4	M45008
Pathway	REACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING	PSMF1 GNB4 GNB1 GNB2 GNB3 SMURF2	4.83e-04	123	114	6	MM14988
Pathway	REACTOME_GLUCOSE_METABOLISM	RGPD4 RANBP2 RGPD8 RGPD3 PKM	5.26e-04	82	114	5	MM15394
Pathway	REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS	RGPD4 RANBP2 RGPD8 RGPD3	5.53e-04	47	114	4	MM14939
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	GNB4 GNB1 GNB2 GNB3	6.00e-04	48	114	4	M10775
Pathway	REACTOME_GENE_SILENCING_BY_RNA	RGPD4 RANBP2 RGPD8 RGPD3	6.49e-04	49	114	4	MM14837
Pathway	REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM	RGPD4 RANBP2 RGPD8 DHX38 RGPD3	6.55e-04	86	114	5	MM15413
Pathway	REACTOME_PLATELET_HOMEOSTASIS	GUCY1A1 GNB4 GNB1 GNB2 GNB3	6.55e-04	86	114	5	M916
Pathway	REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS	RGPD4 RANBP2 RGPD8 RGPD3	7.01e-04	50	114	4	MM14610
Pathway	REACTOME_SIGNALING_BY_WNT	PSMF1 TRRAP GNB4 KLHL12 GNB1 GNB2 GNB3 SMURF2	7.13e-04	239	114	8	MM14756
Pathway	REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS	RGPD4 RANBP2 RGPD8 RGPD3	7.56e-04	51	114	4	MM15151
Pathway	REACTOME_AQUAPORIN_MEDIATED_TRANSPORT	GNB4 GNB1 GNB2 GNB3	8.14e-04	52	114	4	M920
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR	CFH CFHR1	9.52e-04	6	114	2	M47880
Pathway	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	SCTR GNB4 GNB1 GNB2 GNB3	9.81e-04	94	114	5	M797
Pathway	REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN	RGPD4 RANBP2 RGPD8 RGPD3	1.01e-03	55	114	4	MM14917
Pathway	REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION	GRIK5 GNB4 GNB1 GNB2 GNB3 GABRA4	1.10e-03	144	114	6	MM14501
Pathway	REACTOME_PROTEIN_FOLDING	GNB4 GNB1 GNB2 GNB3 KIF13A	1.18e-03	98	114	5	M776
Pathway	REACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING	PSMF1 GNB4 GNB1 GNB2 GNB3 SMURF2	1.19e-03	146	114	6	M27288
Pathway	REACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS	RGPD4 RANBP2 RGPD8 RGPD3	1.23e-03	58	114	4	MM15149
Pathway	REACTOME_SNRNP_ASSEMBLY	RGPD4 RANBP2 RGPD8 RGPD3	1.23e-03	58	114	4	MM14736
Pathway	KEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_DEGRADATION	IDUA GUSB	1.33e-03	7	114	2	M47608
Pathway	REACTOME_CA2_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.58e-03	62	114	4	M27321
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	RAPGEF4 GNB4 GNB1 GNB2 GNB3	1.82e-03	108	114	5	M17034
Pathway	REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS	RGPD4 RANBP2 RGPD8 RGPD3	1.88e-03	65	114	4	MM15147
Pathway	REACTOME_GAMMA_CARBOXYLATION_OF_PROTEIN_PRECURSORS	F2 GGCX	2.25e-03	9	114	2	MM14613
Pathway	REACTOME_BETA_OXIDATION_OF_PRISTANOYL_COA	CRAT ACOXL	2.25e-03	9	114	2	M27294
Pubmed	The gene for the beta-subunit of retinal transducin (Gnb-1) maps to distal mouse chromosome 4, and related sequences map to mouse chromosomes 5 and 8.	GUSB GNB4 GNB1 GNB2 GNB3	1.01e-10	8	158	5	2328987
Pubmed	Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA.	GNB4 GNB1 GNB2 GNB3	4.10e-10	4	158	4	1543505
Pubmed	The role of G protein beta subunits in the release of ATP from human erythrocytes.	GNB4 GNB1 GNB2 GNB3	4.10e-10	4	158	4	12512701
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	CFH CFHR1 MINPP1 F2 FCGBP GUSB ACAN NECTIN1 C1R C8B CDH5 IL6ST	2.60e-09	257	158	12	16335952
Pubmed	Identification of Gnr1p, a negative regulator of G alpha signalling in Schizosaccharomyces pombe, and its complementation by human G beta subunits.	GNB4 GNB1 GNB2 GNB3	6.11e-09	6	158	4	16884933
Pubmed	Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	9037092
Pubmed	Complex genomic rearrangements lead to novel primate gene function.	RGPD4 RGPD8 RGPD3 RGPD5	1.42e-08	7	158	4	15710750
Pubmed	Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	11353387
Pubmed	Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	30944974
Pubmed	Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	38838144
Pubmed	Retina-specifically expressed novel subtypes of bovine cyclophilin.	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	7559465
Pubmed	Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	17372272
Pubmed	Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	38657106
Pubmed	Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	21205196
Pubmed	Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	18949001
Pubmed	Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	25187515
Pubmed	Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	8603673
Pubmed	Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	26632511
Pubmed	Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	24403063
Pubmed	Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	23818861
Pubmed	Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	23536549
Pubmed	Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	12191015
Pubmed	Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	22821000
Pubmed	Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.	RGPD4 RANBP2 RGPD8 RGPD3	1.42e-08	7	158	4	20682751
Pubmed	The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.	RGPD4 RANBP2 RGPD8 RGPD3	2.83e-08	8	158	4	21670213
Pubmed	Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.	RGPD4 RANBP2 RGPD8 RGPD3	2.83e-08	8	158	4	27412403
Pubmed	Mice lacking Ran binding protein 1 are viable and show male infertility.	RGPD4 RANBP2 RGPD8 RGPD3	2.83e-08	8	158	4	21310149
Pubmed	The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.	RGPD4 RANBP2 RGPD8 RGPD3	2.83e-08	8	158	4	22262462
Pubmed	Expression of testicular germ cell genes identified by differential display analysis.	ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	2.83e-08	8	158	4	12634303
Pubmed	Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.	RGPD4 RANBP2 RGPD8 RGPD3	2.83e-08	8	158	4	28745977
Pubmed	Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.	RGPD4 RANBP2 RGPD8 RGPD3	5.08e-08	9	158	4	18394993
Pubmed	Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.	RGPD4 RANBP2 RGPD8 RGPD3	5.08e-08	9	158	4	28100513
Pubmed	Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.	RGPD4 RANBP2 RGPD8 RGPD3	5.08e-08	9	158	4	17887960
Pubmed	Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11.	GNB4 GNB1 GNB2 GNB3	5.08e-08	9	158	4	10339615
Pubmed	The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.	RGPD4 RANBP2 RGPD8 RGPD3	5.08e-08	9	158	4	11553612
Pubmed	The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.	RGPD4 RANBP2 RGPD8 RGPD3	5.08e-08	9	158	4	10601307
Pubmed	The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.	RGPD4 RANBP2 RGPD8 RGPD3	5.08e-08	9	158	4	9733766
Pubmed	Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.	RGPD4 RANBP2 RGPD8 RGPD3	5.08e-08	9	158	4	28877029
Pubmed	The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.	RGPD4 RANBP2 RGPD8 RGPD3	8.43e-08	10	158	4	27160050
Pubmed	Parkin ubiquitinates and promotes the degradation of RanBP2.	RGPD4 RANBP2 RGPD8 RGPD3	8.43e-08	10	158	4	16332688
Pubmed	Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.	RGPD4 RANBP2 RGPD8 RGPD3	8.43e-08	10	158	4	8857542
Pubmed	Gβ2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex.	GNB4 GNB1 GNB2 GNB3	8.43e-08	10	158	4	28334111
Pubmed	Expression of olfactory receptors, G-proteins and AxCAMs during the development and maturation of olfactory sensory neurons in the mouse.	GNB4 GNB1 GNB2 GNB3	8.43e-08	10	158	4	9733924
Pubmed	Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.	RGPD4 RANBP2 RGPD8 RGPD3	8.43e-08	10	158	4	21859863
Pubmed	Genomic organization of the murine G protein beta subunit genes and related processed pseudogenes.	GNB1 GNB2 GNB3	9.20e-08	3	158	3	11913780
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DDX17 RGPD8 SYNE1 EFTUD2 ASPM CGNL1 HERC1 CAMSAP1 KIF13A DDX21	1.31e-07	234	158	10	36243803
Pubmed	The G protein subunit gene families.	GNB4 GNB1 GNB2 GNB3	1.32e-07	11	158	4	10644457
Pubmed	RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.	RGPD4 RANBP2 RGPD8 RGPD3	1.32e-07	11	158	4	17069463
Pubmed	An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.	RGPD4 RANBP2 RGPD8 RGPD3	1.32e-07	11	158	4	35771867
Pubmed	A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation.	GNB4 GNB1 GNB2 GNB3	1.32e-07	11	158	4	25982117
Pubmed	T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.	RGPD4 RANBP2 RGPD8 RGPD3	1.32e-07	11	158	4	34110283
Pubmed	Neural tube defects and impaired neural progenitor cell proliferation in Gbeta1-deficient mice.	GNB4 GNB1 GNB2 GNB3	1.97e-07	12	158	4	20186915
Pubmed	Differential sensitivity of P-Rex1 to isoforms of G protein betagamma dimers.	GNB4 GNB1 GNB2 GNB3	1.97e-07	12	158	4	16301321
Pubmed	Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families.	GNB4 GNB1 GNB2 GNB3	1.97e-07	12	158	4	8636150
Pubmed	Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.	RGPD4 RANBP2 RGPD8 RGPD3	2.84e-07	13	158	4	31427429
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	RGPD4 RANBP2 DCAF6 DDX17 RGPD8 MRPL47 SYNE1 DHX38 EFTUD2 GTF3C1 KIN RGPD3 ASPM PKM GNB4 GNB1 GNB2 FSCN1 DDX21 RGPD5	3.25e-07	1155	158	20	20360068
Pubmed	Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.	RANBP2 RGPD8 RGPD5	3.67e-07	4	158	3	9480752
Pubmed	The cationic region of Rhes mediates its interactions with specific Gbeta subunits.	GNB1 GNB2 GNB3	3.67e-07	4	158	3	19255495
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RAD51 RGPD4 RANBP2 RGPD8 ZNF280D MYCBP2 RFX1 ZBTB1 GTF3C1 RGPD3 ZBTB10 CAMSAP1	5.28e-07	418	158	12	34709266
Pubmed	Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta.	GNB4 GNB1 GNB2 GNB3	5.38e-07	15	158	4	12486123
Pubmed	Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.	RGPD4 RANBP2 RGPD8 RGPD3	5.38e-07	15	158	4	14697343
Pubmed	Role of molecular chaperones in G protein beta5/regulator of G protein signaling dimer assembly and G protein betagamma dimer specificity.	GNB4 GNB1 GNB2 GNB3	9.32e-07	17	158	4	19376773
Pubmed	Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.	MRPS31 MYCBP2 MRPL47 F2 POGLUT1 SLC25A1 GNB2 FSCN1 ZNF512	1.10e-06	228	158	9	30471916
Pubmed	Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors.	GNB4 GNB1 GNB2	1.82e-06	6	158	3	16371464
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RGPD4 RANBP2 RGPD8 FOXP2 MYCBP2 SYNE1 RAPGEF4 GRIK5 DNAJC6 ZBTB1 SHANK3 EFTUD2 RGPD3 GNB1 GNB2 FSCN1 CAMSAP1	2.05e-06	963	158	17	28671696
Pubmed	Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.	FOXP2 DOCK8 RAPGEF4 NPAS3 RFX6 ZBTB7B ZBTB1 CBY2 KLHL12 LNX1 GABRA4	2.53e-06	402	158	11	24722188
Pubmed	Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.	RGPD4 RANBP2 RGPD8 RGPD3	2.81e-06	22	158	4	27717094
Pubmed	Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium.	GNB4 GNB1 GNB3	3.18e-06	7	158	3	10570481
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	MRPS31 RANBP2 DDX17 DHX38 GRIK5 TRRAP MAP3K4 GTF3C1 SLC25A1 RGPD3 PKM GNB1 GNB2 FSCN1	4.48e-06	704	158	14	29955894
Pubmed	A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits.	GNB1 GNB2 GNB3	5.07e-06	8	158	3	9789084
Pubmed	Gβγ interacts with mTOR and promotes its activation.	GNB1 GNB2 GNB3	5.07e-06	8	158	3	24462769
Pubmed	Ataxin 10 induces neuritogenesis via interaction with G-protein beta2 subunit.	ABCA1 GNB1 GNB2	7.57e-06	9	158	3	16498633
Pubmed	G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development.	GNB4 GNB1 GNB2 GNB3	7.71e-06	28	158	4	8858601
Pubmed	Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.	RGPD4 RANBP2 RGPD8 EFTUD2 SLC25A1 RGPD3 GNB2 DDX21	9.80e-06	226	158	8	37839992
Pubmed	Methylation of the DNA/RNA-binding protein Kin17 by METTL22 affects its association with chromatin.	DDX17 EFTUD2 KIN DDX21	1.02e-05	30	158	4	24140279
Pubmed	Glucagon and regulation of glucose metabolism.	GNB4 GNB1 GNB2 GNB3	1.17e-05	31	158	4	12626323
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RANBP2 DDX17 MYCBP2 DHX38 SRCAP DUS3L ATAD2 TRRAP EFTUD2 ARAP3 GTF3C1 SLC25A1 ASPM PKM ZBTB10 GNB2 FSCN1 ZNF512 DDX21	1.34e-05	1353	158	19	29467282
Pubmed	Specificities of Gβγ subunits for the SNARE complex before and after stimulation of α2a-adrenergic receptors.	GNB4 GNB1 GNB2	1.48e-05	11	158	3	34932372
Pubmed	Human Multisubunit E3 Ubiquitin Ligase Required for Heterotrimeric G-Protein β-Subunit Ubiquitination and Downstream Signaling.	GNB4 GNB1 GNB2	1.96e-05	12	158	3	34342229
Pubmed	SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR.	ABCA1 SREBF2	2.05e-05	2	158	2	16901265
Pubmed	Different roles of G protein subunits beta1 and beta2 in neutrophil function revealed by gene expression silencing in primary mouse neutrophils.	GNB1 GNB2	2.05e-05	2	158	2	20525682
Pubmed	Factor H and CFHR1 polymorphisms associated with atypical Haemolytic Uraemic Syndrome (aHUS) are differently expressed in Tunisian and in Caucasian populations.	CFH CFHR1	2.05e-05	2	158	2	22136554
Pubmed	Deciphering the ligand-binding sites in the Borrelia burgdorferi complement regulator-acquiring surface protein 2 required for interactions with the human immune regulators factor H and factor H-like protein 1.	CFH CFHR1	2.05e-05	2	158	2	18824548
Pubmed	[Overexpression of NHE1 suppresses ABCA1 protein expression via increasing calpain activity in RAW264.7 cells].	ABCA1 SLC9A1	2.05e-05	2	158	2	28031107
Pubmed	Anti-factor H autoantibody-associated hemolytic uremic syndrome: review of literature of the autoimmune form of HUS.	CFH CFHR1	2.05e-05	2	158	2	20865640
Pubmed	A synthetic protein as efficient multitarget regulator against complement over-activation.	CFH CFHR1	2.05e-05	2	158	2	35194132
Pubmed	Complement factor H-related protein 1 deficiency and factor H antibodies in pediatric patients with atypical hemolytic uremic syndrome.	CFH CFHR1	2.05e-05	2	158	2	23243267
Pubmed	Cloning of the 1.4-kb mRNA species of human complement factor H reveals a novel member of the short consensus repeat family related to the carboxy terminal of the classical 150-kDa molecule.	CFH CFHR1	2.05e-05	2	158	2	1826708
Pubmed	Exon 2 deletion splice variant of gamma-glutamyl carboxylase causes des-gamma-carboxy prothrombin production in hepatocellular carcinoma cell lines.	F2 GGCX	2.05e-05	2	158	2	19383345
Pubmed	Human complement factor H and factor H-like protein 1 are expressed in human retinal pigment epithelial cells.	CFH CFHR1	2.05e-05	2	158	2	24280833
Pubmed	A novel hybrid CFHR1/CFH gene causes atypical hemolytic uremic syndrome.	CFH CFHR1	2.05e-05	2	158	2	23880784
Pubmed	Binding of the human complement regulators CFHR1 and factor H by streptococcal collagen-like protein 1 (Scl1) via their conserved C termini allows control of the complement cascade at multiple levels.	CFH CFHR1	2.05e-05	2	158	2	20855886
Pubmed	Complement factor H: a biomarker for progression of cutaneous squamous cell carcinoma.	CFH CFHR1	2.05e-05	2	158	2	23938460
Pubmed	KIN17 functions in DNA damage repair and chemosensitivity by modulating RAD51 in hepatocellular carcinoma.	RAD51 KIN	2.05e-05	2	158	2	38935235
Pubmed	RFX1 and RFX3 Transcription Factors Interact with the D Sequence of Adeno-Associated Virus Inverted Terminal Repeat and Regulate AAV Transduction.	RFX1 RFX3	2.05e-05	2	158	2	29317724
Pubmed	CFH-CFHR1 hybrid genes in two cases of atypical hemolytic uremic syndrome.	CFH CFHR1	2.05e-05	2	158	2	36755127
Pubmed	Deregulation of Factor H by Factor H-Related Protein 1 Depends on Sialylation of Host Surfaces.	CFH CFHR1	2.05e-05	2	158	2	33732239
Pubmed	Process of carboxylation of glutamic acid residues in the gla domain of human des-gamma-carboxyprothrombin.	F2 GGCX	2.05e-05	2	158	2	10556651
Pubmed	Interaction between complement regulators and Streptococcus pyogenes: binding of C4b-binding protein and factor H/factor H-like protein 1 to M18 strains involves two different cell surface molecules.	CFH CFHR1	2.05e-05	2	158	2	15557185
Pubmed	Factor H-related protein 1 neutralizes anti-factor H autoantibodies in autoimmune hemolytic uremic syndrome.	CFH CFHR1	2.05e-05	2	158	2	21677636
Interaction	RGS6 interactions	TRRAP GNB4 GNB1 GNB2 GNB3	1.87e-07	18	153	5	int:RGS6
Interaction	RGPD4 interactions	RGPD4 RANBP2 RGPD8 RGPD3 RGPD5	5.60e-07	22	153	5	int:RGPD4
Interaction	GNGT2 interactions	GNB4 GNB1 GNB2 GNB3	1.51e-06	12	153	4	int:GNGT2
Interaction	RGPD2 interactions	RGPD4 RANBP2 RGPD8 RGPD3 RGPD5	1.67e-06	27	153	5	int:RGPD2
Interaction	TRIM28 interactions	MRPS31 ZNF567 RANBP2 DDX17 ZNF695 ZNF493 MYCBP2 DHX38 GRIK5 SRCAP TRRAP ZBTB1 SHANK3 MAP3K4 EFTUD2 ZNF17 GTF3C1 ZNF257 SLC25A1 RGPD3 PKM ZNF766 GNB1 GNB2 FSCN1 ZNF512 DDX21 SMURF2 ZNF443	1.85e-06	1474	153	29	int:TRIM28
Interaction	GNG11 interactions	GNB4 GNB1 GNB2 GNB3	7.04e-06	17	153	4	int:GNG11
Interaction	ANKRD20A4P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	8.44e-06	6	153	3	int:ANKRD20A4P
Interaction	GNG7 interactions	GNB4 GNB1 GNB2 GNB3	1.41e-05	20	153	4	int:GNG7
Interaction	GNG13 interactions	CCHCR1 GNB4 GNB1 GNB2 GNB3	1.42e-05	41	153	5	int:GNG13
Interaction	ANKRD20A2P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	1.47e-05	7	153	3	int:ANKRD20A2P
Interaction	RGPD8 interactions	RGPD4 RANBP2 RGPD8 MYCBP2 RGPD3 RGPD5	2.10e-05	74	153	6	int:RGPD8
Interaction	RGPD3 interactions	RGPD4 RANBP2 RGPD8 RGPD3 RGPD5	2.80e-05	47	153	5	int:RGPD3
Interaction	GNG3 interactions	GNB4 GNB1 GNB2 GNB3	3.02e-05	24	153	4	int:GNG3
Interaction	RGPD1 interactions	RGPD4 RANBP2 RGPD8 RGPD3 RGPD5	3.44e-05	49	153	5	int:RGPD1
Interaction	RASD2 interactions	GNB1 GNB2 GNB3 SMURF2	3.57e-05	25	153	4	int:RASD2
Interaction	GNG4 interactions	GNB4 GNB1 GNB2 GNB3	3.57e-05	25	153	4	int:GNG4
Interaction	GNGT1 interactions	GNB4 GNB1 GNB2 GNB3	4.19e-05	26	153	4	int:GNGT1
Interaction	NFIX interactions	SRCAP ZBTB7B RFX1 TRRAP GTF3C1 ZBTB10 GATAD1 ZNF512 MYBPC3	6.10e-05	227	153	9	int:NFIX
Interaction	ANKRD20A1 interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	6.77e-05	11	153	3	int:ANKRD20A1
Interaction	LYZL6 interactions	DCAF6 IDUA CEMIP2 POGLUT1	9.73e-05	32	153	4	int:LYZL6
Cytoband	2q13	RGPD8 RGPD3 ACOXL RGPD5	9.26e-05	68	158	4	2q13
GeneFamily	WD repeat domain containing	DCAF6 CORO2A DCAF12L2 LYST GNB4 HERC1 MAPKBP1 GNB1 GNB2 GNB3 NSMAF	7.57e-07	262	113	11	362
GeneFamily	Regulatory factor X family	RFX6 RFX1 RFX3	1.30e-05	8	113	3	1153
GeneFamily	Complement system\|Sushi domain containing	CFH CFHR1 C1R C8B	7.30e-05	36	113	4	492
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF567 ZNF695 ZNF493 ZNF510 ZBTB7B ZBTB1 ZNF17 ZSCAN32 ZNF257 ZBTB10 ZNF766 ZNF860 ZNF512 ZNF443	1.54e-04	718	113	14	28
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CFH CFHR1 ACAN C1R	4.43e-04	57	113	4	1179
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	RGPD4 RANBP2 RGPD8 RGPD3 RGPD5	7.76e-04	115	113	5	769
GeneFamily	Ankyrin repeat domain containing	ANKRD20A2P ANKRD20A3P SHANK3 ARAP3 ANKRD20A4P ANKRD20A1 PPP1R16A	8.18e-04	242	113	7	403
GeneFamily	WD repeat domain containing\|BEACH domain containing	LYST NSMAF	1.35e-03	9	113	2	1230
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KLHL6 ZBTB7B ZBTB1 ZBTB10 KLHL12	1.54e-03	134	113	5	861
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_500	FOXP2 RAPGEF4 NPAS3 SEC24D CHSY3 GABRA4	9.05e-06	70	147	6	gudmap_developingLowerUrinaryTract_e14.5_ bladder_500_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#4_top-relative-expression-ranked_100	FOXP2 NPAS3 CHSY3 GABRA4	1.76e-05	23	147	4	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k4_100
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_1000	CFH DCAF6 ARHGAP5 TENM4 HERC1 CPLANE1 GABRA4	2.95e-05	127	147	7	gudmap_developingGonad_e16.5_epididymis_1000_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000	ABCA1 FOXP2 MYCBP2 RAPGEF4 VPS13A ASPM SHPRH FSCN1 CPLANE1 MMP16 SUCO	5.41e-05	369	147	11	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000	ABCA1 DDX17 FOXP2 MYCBP2 RAPGEF4 TENM4 SHPRH FSCN1 CAMSAP1 CPLANE1 KIF13A	7.90e-05	385	147	11	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_500	CFH SRCAP TENM4 HERC1 CPLANE1 MMP16	1.01e-04	107	147	6	gudmap_developingGonad_e14.5_ epididymis_500_k2
CoexpressionAtlas	Myeloid Cells, DC.IIhilang-103-11b+.SLN, MHCIIhi CD11c+ Langerin- CD103- CD11b+, Lymph Node, avg-3	LAD1 EXTL1 SLAMF1 LYST ARHGAP5 SLC44A1 POGLUT1 NECTIN1 ZBTB10 GNB4 FSCN1	1.40e-04	411	147	11	GSM538274_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000	ABCA1 FOXP2 MYCBP2 LAD1 RAPGEF4 NPAS3 TENM4 GUCY1A1 VPS13A ASPM SHPRH FSCN1 CPLANE1 MMP16 SUCO IL6ST	1.51e-04	806	147	16	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_500	FOXP2 RAPGEF4 NPAS3 SEC24D ASPM SHPRH CHSY3 CPLANE1 MMP16 IL6ST GABRA4	1.73e-04	421	147	11	gudmap_developingLowerUrinaryTract_e14.5_ bladder_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000	ABCA1 DDX17 FOXP2 MYCBP2 RAPGEF4 NPAS3 DNAJC6 TENM4 SHPRH CHSY3 FSCN1 CAMSAP1 CPLANE1 KIF13A MMP16 IL6ST	1.79e-04	818	147	16	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SH2D3C RAPGEF4 SHANK3 ITIH5 ARAP3 GUCY1A1 FSCN1 MMP16 CDH5	2.61e-08	190	157	9	106ea0bb7b99c697ffc5443d72343df2484250c7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FOXP2 TENM4 GUCY1A1 MYO3B PKM SCTR CGNL1 LNX1	2.37e-07	178	157	8	4df6218b20c2f076c22346d23260964cc0d73e65
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D231\|Adult / Lineage, Cell type, age group and donor	SH2D3C RAPGEF4 ANKRD20A2P SHANK3 CEMIP2 ARAP3 FSCN1 CDH5	3.18e-07	185	157	8	07f9f38f0739d7c830641723a38385550ac1ac92
ToppCell	Control-Myeloid-cDC1\|Control / Disease state, Lineage and Cell class	KLHL6 ANKRD20A2P ANKRD20A3P ANKRD20A8P ARHGAP5 TENM4 ANKRD20A4P ANKRD20A1	3.31e-07	186	157	8	b05c394aa3573ba855abc3066739ca193883b0c3
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SH2D3C RAPGEF4 SHANK3 ARAP3 FSCN1 KIF13A MMP16 CDH5	4.39e-07	193	157	8	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SH2D3C RAPGEF4 SHANK3 ARAP3 FSCN1 KIF13A MMP16 CDH5	4.39e-07	193	157	8	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	RAPGEF4 ANKRD20A2P ANKRD20A3P GTF2IRD1 ATAD2 CEMIP2 ANKRD20A4P SMURF2	5.13e-07	197	157	8	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SH2D3C RAPGEF4 NPAS3 SHANK3 ARAP3 FSCN1 MMP16 CDH5	5.33e-07	198	157	8	9ab0db78394e730f6866b2db80047149024ad5f6
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SH2D3C RAPGEF4 NPAS3 SHANK3 ARAP3 FSCN1 MMP16 CDH5	5.33e-07	198	157	8	e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 SH2D3C RAPGEF4 SHANK3 SLC44A1 FSCN1 CDH5 IL6ST	5.53e-07	199	157	8	5d976d57872a8a25a11fe8cd53b01aa21a1a519a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SH2D3C ANKRD20A2P SHANK3 FGF18 ARAP3 CDH5 SMURF2	2.02e-06	165	157	7	a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CFHR1 PI15 GUCY1A1 C1R CHSY3 MMP16	2.66e-06	172	157	7	1ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CFHR1 PI15 GUCY1A1 C1R CHSY3 MMP16	2.66e-06	172	157	7	ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 SH2D3C RAPGEF4 SHANK3 ARAP3 CHSY3 CDH5	2.76e-06	173	157	7	afa6bb19df52541d8d17cbfac9cbdd18a5f3632d
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175\|Adult / Lineage, Cell type, age group and donor	SH2D3C RAPGEF4 ANKRD20A8P SHANK3 ARAP3 LNX1 CDH5	3.86e-06	182	157	7	8b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NPAS3 ANKRD20A3P SHANK3 FSCN1 MMP16 CDH5 IL6ST	4.00e-06	183	157	7	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	Control-Endothelial-VE_Capillary_A\|World / Disease state, Lineage and Cell class	SYNE1 SH2D3C RAPGEF4 ANKRD20A2P ANKRD20A3P SHANK3 CDH5	4.30e-06	185	157	7	a28187c2fd23564314b35759479ff2ca21f61485
ToppCell	356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	SH2D3C RAPGEF4 ANKRD20A3P SHANK3 ARAP3 FSCN1 CDH5	4.45e-06	186	157	7	f0b78c7ee20279970ea8961bf59acb5262f2dce5
ToppCell	356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|356C / Donor, Lineage, Cell class and subclass (all cells)	SH2D3C RAPGEF4 ANKRD20A3P SHANK3 ARAP3 FSCN1 CDH5	4.45e-06	186	157	7	2b3c814a7dee8286ea113c63dc3de5daf0257d37
ToppCell	Control-Endothelial-VE_Capillary_A\|Control / Disease state, Lineage and Cell class	SYNE1 SH2D3C RAPGEF4 ANKRD20A2P ANKRD20A3P SHANK3 CDH5	4.61e-06	187	157	7	54d7588172ac145ff5045ad9771636729ca3f0ca
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SH2D3C RAPGEF4 SHANK3 ITIH5 FSCN1 MMP16 CDH5	4.78e-06	188	157	7	789d1be574e693d7bdd488f3c72c6df788e47b47
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D122\|Adult / Lineage, Cell type, age group and donor	SH2D3C RAPGEF4 ANKRD20A3P SHANK3 CEMIP2 ARAP3 CDH5	4.78e-06	188	157	7	02a62888e9db29d20133eeca1686d302545a39c9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH SH2D3C RAPGEF4 SHANK3 ITIH5 ARAP3 CDH5	4.95e-06	189	157	7	6463890d8dbee4bc198f91628a5f784970de786a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF4 NPAS3 SHANK3 CEMIP2 ARAP3 CDH5 IL6ST	5.12e-06	190	157	7	656483751e4bf137e4e4bfb2a03a478a8f7fcb63
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	SYNE1 RAPGEF4 ANKRD20A2P CEMIP2 ANKRD20A4P CDH5 SMURF2	5.12e-06	190	157	7	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	droplet-Heart-nan-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PI15 ITIH5 IGSF10 GUCY1A1 MMP16 SBK3	5.12e-06	190	157	7	96a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell	COPD-Myeloid-cDC1\|COPD / Disease state, Lineage and Cell class	KLHL6 ANKRD20A2P ANKRD20A3P ANKRD20A8P ARHGAP5 ANKRD20A4P ANKRD20A1	5.49e-06	192	157	7	bd3d00b094d92463b06023361a71240851a542b8
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 DDX17 RAPGEF4 RFX6 ARHGAP5 TRPM5 PKM	5.49e-06	192	157	7	1304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SH2D3C RAPGEF4 SHANK3 ARAP3 FSCN1 MMP16 CDH5	5.68e-06	193	157	7	e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_mature_DC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	DCAF6 LAD1 LYST SLC44A1 POGLUT1 ZBTB10 FSCN1	5.68e-06	193	157	7	d9be4d1de863fffc2240d6fd1a2f8dfb2d2bc916
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 SH2D3C RAPGEF4 SHANK3 ARAP3 CDH5 IL6ST	5.68e-06	193	157	7	456aa8a8f1f9cbba0bd618a5f623909079c0f56b
ToppCell	RV-09._Endothelium_I\|RV / Chamber and Cluster_Paper	SYNE1 SH2D3C SHANK3 ARAP3 CHSY3 LNX1 CDH5	5.87e-06	194	157	7	7b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 MYCBP2 RAPGEF4 RFX6 VPS13A PKM HERC1	6.07e-06	195	157	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 MYCBP2 RAPGEF4 RFX6 VPS13A PKM HERC1	6.07e-06	195	157	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 RAPGEF4 SHANK3 ARAP3 FSCN1 CDH5 IL6ST	6.28e-06	196	157	7	d323f7dc41380446e5967c69832bea88351a9331
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 SH2D3C RAPGEF4 SHANK3 FSCN1 CDH5 IL6ST	6.28e-06	196	157	7	65d882c6e7f6d5778b8a5fd4fdaf012e1b9f6100
ToppCell	BAL-Mild-cDC_10\|Mild / Compartment, Disease Groups and Clusters	DCAF6 LAD1 LYST POGLUT1 ZBTB10 FSCN1 IL6ST	6.49e-06	197	157	7	c0550d41dd5619b369b590f3d6a61154dd7b2cab
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 SH2D3C RAPGEF4 SHANK3 ARAP3 CDH5 IL6ST	6.71e-06	198	157	7	92416e65a0dc1a4bf931833407620ea05d362f56
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SH2D3C RAPGEF4 SHANK3 ARAP3 FSCN1 CDH5 IL6ST	6.93e-06	199	157	7	8b62d43af8b2ebb4c1b2d068d50beaf35728dbe7
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SH2D3C RAPGEF4 SHANK3 ARAP3 FSCN1 CDH5 IL6ST	6.93e-06	199	157	7	da5a88749d859d535daa030d0974485906cc0ba7
ToppCell	BAL-Severe-cDC_10\|Severe / Compartment, Disease Groups and Clusters	DCAF6 LAD1 SLAMF1 LYST POGLUT1 FSCN1 SUCO	6.93e-06	199	157	7	54bdadd04abaf8caa948b0177c037bc089ca07e6
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 SH2D3C RAPGEF4 SHANK3 FSCN1 CDH5 IL6ST	6.93e-06	199	157	7	14e09eaa2335d4503de50250eb4258dd5b85b304
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SH2D3C RAPGEF4 SHANK3 ARAP3 FSCN1 CDH5 IL6ST	6.93e-06	199	157	7	e6715288a586631676722f2323f0d833431161cf
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH NPAS3 TENM4 ACAN C1R MMP16 ADGRA3	6.93e-06	199	157	7	abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SH2D3C RAPGEF4 SHANK3 ARAP3 FSCN1 CDH5 IL6ST	7.16e-06	200	157	7	b1be27d134a8633e3e7862c6a0d7be2001d387f0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SH2D3C RAPGEF4 SHANK3 ARAP3 FSCN1 CDH5 IL6ST	7.16e-06	200	157	7	dba96cda5f3b780a3d4171b61bc8aaddc1f5d466
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SH2D3C RAPGEF4 SHANK3 ARAP3 FSCN1 CDH5 IL6ST	7.16e-06	200	157	7	2e47888e041ec3d265425d1df97b6665c6da889c
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 SH2D3C RAPGEF4 SHANK3 FSCN1 CDH5 IL6ST	7.16e-06	200	157	7	3007583eaad3a5ae2df010513d3e4df59155123d
ToppCell	kidney_cells-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 SH2D3C RAPGEF4 SHANK3 FSCN1 CDH5 IL6ST	7.16e-06	200	157	7	9f1626a7e1bd00977a5c316cafbdf654b52bad94
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SH2D3C RAPGEF4 SHANK3 ARAP3 FSCN1 CDH5 IL6ST	7.16e-06	200	157	7	ced14d83222dbebca85c40540e76824e683354f3
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SH2D3C RAPGEF4 SHANK3 ARAP3 FSCN1 CDH5 IL6ST	7.16e-06	200	157	7	7a69ad5b6c84f1aebacea5cacb9bc5c63dfd1dac
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RAD51 EXTL1 ATAD2 FSCN1 CAMSAP1 CDH5	1.33e-05	146	157	6	2d907e50206c4762a8baa741363bc7f0a04bd84e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FOXP2 TENM4 MYO3B SCTR CGNL1 LNX1	2.23e-05	160	157	6	03b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCell	PND14-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLHL6 MPC2 RAPSN CORO2A SYNE1 NCF1	2.57e-05	164	157	6	f4de9f18134a06f3d7fcf5b50b8e21c1506e2083
ToppCell	PND14-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLHL6 MPC2 RAPSN CORO2A SYNE1 NCF1	2.57e-05	164	157	6	dc22b1fef49c1557a0b63c536eaba574dfcab715
ToppCell	droplet-Lung-LUNG-1m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51 LAD1 EXTL1 NECTIN1 GNB4 FSCN1	2.84e-05	167	157	6	e30e7ac8ea4399dc3c1d94fc6b857afc80a7a671
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	OTUD1 FCGBP GUCY1A1 NECTIN1 CAMSAP1 LNX1	2.94e-05	168	157	6	d7d19c93d1c3dd994e18e28d5f36ae7773ff5d7f
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D122\|Adult / Lineage, Cell type, age group and donor	GLYATL3 SHANK3 FGF18 ARAP3 ZNF257 CDH5	2.94e-05	168	157	6	8c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF4 SHANK3 ARAP3 FSCN1 CDH5 IL6ST	2.94e-05	168	157	6	37249f38f8f04ec5743097259de67b106ca2b02f
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGLYRP1 SYNE1 NCF1 LYST ARAP3 GNB2	3.04e-05	169	157	6	2341eddfedaad8cee779c37bb87f7def058588ca
ToppCell	facs-Marrow-Granulocytes-18m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGLYRP1 SYNE1 NCF1 LYST ARAP3 GNB2	3.04e-05	169	157	6	94871936ccfc73b56d425373b989b87c059d4493
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLHL6 RAPSN SYNE1 NCF1 LYST HERC1	3.35e-05	172	157	6	c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLHL6 RAPSN SYNE1 NCF1 LYST HERC1	3.35e-05	172	157	6	953b05f776348cff784e79c93df65841939d880f
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-stromal_related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH NPAS3 PI15 IGSF10 C1R MMP16	3.69e-05	175	157	6	b8995e7ada85ba959f06264a0295b61e390c4e6c
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-stromal_related-T_reticular\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH NPAS3 PI15 IGSF10 C1R MMP16	3.69e-05	175	157	6	7ae76bd3b4f610b2f98716a4456437cd3696b686
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH RANBP2 LYST IGSF10 ARHGAP5 GUCY1A1	3.81e-05	176	157	6	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_MEMP\|lymph-node_spleen / Manually curated celltypes from each tissue	GRIK5 MAP7 SHANK3 IGSF10 GUCY1A1 FSCN1	3.81e-05	176	157	6	23a8ec42ebd42c539865a12d09773af90f3f8848
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH2D3C RAPGEF4 SHANK3 ARAP3 LNX1 CDH5	4.06e-05	178	157	6	ba2f0585626988b511046630bc16be5c5fec3fb2
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_10\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GPR31 LAD1 POGLUT1 ZBTB10 GNB3 FSCN1	4.32e-05	180	157	6	32d871738a24071b70084a7e80148a516110c78b
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_10\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GPR31 LAD1 POGLUT1 ZBTB10 GNB3 FSCN1	4.32e-05	180	157	6	067ca8a15228c7f3b3bc7aecbc9b1611ca05e176
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SYNE1 SH2D3C RAPGEF4 SHANK3 ARAP3 CDH5	4.46e-05	181	157	6	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	Control-Hematopoietic_SC-HSPC\|Control / Disease group, lineage and cell class	GRIK5 MAP7 SHANK3 IGSF10 GUCY1A1 FSCN1	4.60e-05	182	157	6	14e347c0e6444410f1948851407bb18c706569f4
ToppCell	Control-Hematopoietic_SC\|Control / Disease group, lineage and cell class	GRIK5 MAP7 SHANK3 IGSF10 GUCY1A1 FSCN1	4.60e-05	182	157	6	43243c6bae2ac7fa3fd1f193a17f61ee4d938ea9
ToppCell	wk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CFH ZNF695 EXTL1 TENM4 ACAN ADGRA3	4.60e-05	182	157	6	03a5a02acd48f0eb210485348bfe0cd21f486215
ToppCell	COVID-19_Severe-Hematopoietic_SC-HSPC\|COVID-19_Severe / Disease group, lineage and cell class	GRIK5 MAP7 SHANK3 IGSF10 GUCY1A1 FSCN1	4.74e-05	183	157	6	4146b1c0e5f76d25226745abfa28f77127a444fc
ToppCell	COVID-19-kidney-Mito-rich_EC\|kidney / Disease (COVID-19 only), tissue and cell type	SYNE1 SH2D3C RAPGEF4 SHANK3 ARAP3 CDH5	4.74e-05	183	157	6	3c4153479fc4ab2d073d92cee120480015555914
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T\|lymph-node_spleen / Manually curated celltypes from each tissue	GRIK5 MAP7 SHANK3 GUCY1A1 NECTIN1 GNB4	4.74e-05	183	157	6	6c55fd737ed31f5b1aa41dc4dba7240521c19022
ToppCell	COVID-19_Severe-Hematopoietic_SC\|COVID-19_Severe / Disease group, lineage and cell class	GRIK5 MAP7 SHANK3 IGSF10 GUCY1A1 FSCN1	4.74e-05	183	157	6	92aab7ce65aca17988bc2add4ff9fb8384e2c21b
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SH2D3C RAPGEF4 SHANK3 ARAP3 MMP16 CDH5	4.74e-05	183	157	6	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	Control-Endothelial-Endothelial-Activated_Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SH2D3C RAPGEF4 SHANK3 ARAP3 KIF13A CDH5	4.74e-05	183	157	6	e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL6 CFH CEMIP2 CGNL1 IL6ST ADGRA3	4.74e-05	183	157	6	b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCell	PBMC-Severe-Hematopoietic-HSPC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GRIK5 MAP7 SHANK3 IGSF10 GUCY1A1 FSCN1	4.88e-05	184	157	6	a6169613c6493b947a176493f542368bfa935dab
ToppCell	Control-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ARHGAP5 ANKRD20A4P ANKRD20A1	4.88e-05	184	157	6	c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCell	PBMC-Severe-Hematopoietic-HSPC-HSPC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GRIK5 MAP7 SHANK3 IGSF10 GUCY1A1 FSCN1	4.88e-05	184	157	6	51d0447699e3b8f01abbde83f26b748bc9f3c723
ToppCell	COPD-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ARHGAP5 ANKRD20A4P ANKRD20A1	4.88e-05	184	157	6	42d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCell	PBMC-Severe-Hematopoietic-HSPC-HSPC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GRIK5 MAP7 SHANK3 IGSF10 GUCY1A1 FSCN1	4.88e-05	184	157	6	f7b0bb45a9055ab34e98b251217f6ec38c75ca22
ToppCell	droplet-Heart-4Chambers-21m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH2D3C CEMIP2 ARAP3 CGNL1 FSCN1 CDH5	4.88e-05	184	157	6	f17d713af4a97dff4eeeab24c405677ef2ffcf84
ToppCell	PBMC-Severe-Hematopoietic-HSPC-HSPC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GRIK5 MAP7 SHANK3 IGSF10 GUCY1A1 FSCN1	4.88e-05	184	157	6	cc01c19180861f491a8dc16d60fabd1215fc4525
ToppCell	PBMC-Severe-Hematopoietic-HSPC-HSPC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GRIK5 MAP7 SHANK3 IGSF10 GUCY1A1 FSCN1	4.88e-05	184	157	6	492c680f0769ba4e651d09c2e8e5d5d271ed08aa
ToppCell	PBMC-Severe-Hematopoietic-HSPC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GRIK5 MAP7 SHANK3 IGSF10 GUCY1A1 FSCN1	4.88e-05	184	157	6	26edbf84216538b80f1ffcc079ee6e385a71fbf9
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFH NPAS3 EXTL1 ACAN MMP16 ADGRA3	5.03e-05	185	157	6	8ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MPC2 CPN1 FGF18 FCGBP PKM SCTR	5.03e-05	185	157	6	6da9a06e1514d5d5f47359a14637f02539846096
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MPC2 CPN1 FGF18 FCGBP PKM SCTR	5.03e-05	185	157	6	4a188e2566a75d1b4f3c879a8c241c277c4b451c
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFH NPAS3 EXTL1 ACAN MMP16 ADGRA3	5.03e-05	185	157	6	b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCell	droplet-Heart-nan-24m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH2D3C RAPGEF4 ARAP3 FSCN1 LNX1 CDH5	5.19e-05	186	157	6	8b316bfed39b91c15d5ae28d9261eb057f113796
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	SH2D3C SHANK3 CEMIP2 ARAP3 CGNL1 IL6ST	5.34e-05	187	157	6	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SH2D3C RAPGEF4 SHANK3 ITIH5 GUCY1A1 CDH5	5.34e-05	187	157	6	f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D175\|Adult / Lineage, Cell type, age group and donor	SH2D3C RAPGEF4 SHANK3 CEMIP2 ARAP3 CDH5	5.34e-05	187	157	6	f3548817f2fded5978137bb252cb628ac199e4f6
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH DHX38 ZNF860 ZNF512 KIF13A ZNF443	5.34e-05	187	157	6	f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SH2D3C RAPGEF4 SHANK3 ITIH5 GUCY1A1 CDH5	5.50e-05	188	157	6	73f6ec915934154f435a376cb274b058ff7c5f35
Drug	Clorgyline	CFH ZNF567 ZNF493 ZNF280D RAPGEF4 ZBTB1 VPS13A ZBTB10 RGPD5	2.10e-06	168	153	9	ctd:D003010
Drug	iduronic acid	CFHR1 IDUA F2 FGF18 GUSB ACAN CHSY3	3.90e-06	96	153	7	CID000018845
Disease	complement factor H-related protein 1 measurement	CFH CFHR1 CPN1 MYO3B ASPM	8.63e-06	56	146	5	EFO_0600054
Disease	Complement deficiency disease	CFH CFHR1 C1R C8B	2.10e-05	33	146	4	C0272242
Disease	inter-alpha-trypsin inhibitor heavy chain H5 measurement	CFH ITIH5	2.43e-05	2	146	2	EFO_0801706
Disease	R-spondin-4 measurement	CFH PSMF1	7.27e-05	3	146	2	EFO_0022019
Disease	anaphase-promoting complex subunit 7 measurement	CFH CFHR1	7.27e-05	3	146	2	EFO_0801381
Disease	HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1	CFH CFHR1	7.27e-05	3	146	2	C2749604
Disease	HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1	CFH CFHR1	7.27e-05	3	146	2	235400
Disease	calnexin measurement	CFH CFHR1	7.27e-05	3	146	2	EFO_0801444
Disease	Hemolytic uremic syndrome, atypical, susceptibility to, 1	CFH CFHR1	7.27e-05	3	146	2	cv:C2749604
Disease	complement factor H-related protein 4A measurement	CFH CFHR1	7.27e-05	3	146	2	EFO_0600057
Disease	histone-lysine N-methyltransferase 2D measurement	CFH CFHR1	7.27e-05	3	146	2	EFO_0801683
Disease	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial measurement	CFH CFHR1	1.45e-04	4	146	2	EFO_0803292
Disease	B-cell antigen receptor complex-associated protein alpha chain measurement	CFH ITIH5	1.45e-04	4	146	2	EFO_0801402
Disease	Chediak-Higashi syndrome (implicated_via_orthology)	LYST NSMAF	1.45e-04	4	146	2	DOID:2935 (implicated_via_orthology)
Disease	kallikrein-5 measurement	CFH CFHR1	1.45e-04	4	146	2	EFO_0020515
Disease	septin-10 measurement	CFH C8B	1.45e-04	4	146	2	EFO_0802053
Disease	cyclin-H measurement	CFH C8B	2.41e-04	5	146	2	EFO_0801508
Disease	myocardial zonula adherens protein measurement	CFH CGNL1	2.41e-04	5	146	2	EFO_0802769
Disease	galectin-1 measurement	CFH C1R	2.41e-04	5	146	2	EFO_0020932
Disease	Membranoproliferative Glomerulonephritis, Type II	CFH CFHR1	3.60e-04	6	146	2	C0268743
Disease	amyloid beta A4 precursor protein-binding family B member 2 measurement	CFH C1R	3.60e-04	6	146	2	EFO_0801379
Disease	Paratuberculosis	F2 C1R	3.60e-04	6	146	2	C0030524
Disease	mediator of RNA polymerase II transcription subunit 1 measurement	CFH CNPY3	3.60e-04	6	146	2	EFO_0008228
Disease	NKG2-E type II integral membrane protein measurement	CFH C8B	3.60e-04	6	146	2	EFO_0801842
Disease	complement C1s subcomponent measurement	CFH CFHR1	3.60e-04	6	146	2	EFO_0008091
Disease	transmembrane protein 2 measurement	CFH CEMIP2	3.60e-04	6	146	2	EFO_0802155
Disease	age-related macular degeneration, COVID-19	CFH CFHR1 CCHCR1 CPN1	3.87e-04	69	146	4	EFO_0001365, MONDO_0100096
Disease	complement factor H-related protein 2 measurement	CFH CFHR1 FGF18	3.95e-04	29	146	3	EFO_0600055
Disease	clusterin measurement	CFH C1R	5.02e-04	7	146	2	EFO_0007655
Disease	C-C motif chemokine 1 measurement	CFH C8B	5.02e-04	7	146	2	EFO_0008041
Disease	r-spondin-3 measurement	CFH C1R	5.02e-04	7	146	2	EFO_0021878
Disease	microcephaly (is_implicated_in)	EFTUD2 ASPM	6.68e-04	8	146	2	DOID:10907 (is_implicated_in)
Disease	neurexophilin-1 measurement	CFH C8B	6.68e-04	8	146	2	EFO_0008244
Disease	atypical hemolytic-uremic syndrome (is_implicated_in)	CFH CFHR1	6.68e-04	8	146	2	DOID:0080301 (is_implicated_in)
Disease	Atypical hemolytic-uremic syndrome	CFH CFHR1	8.56e-04	9	146	2	cv:C2931788
Disease	C3 glomerulopathy	CFH CFHR1	8.56e-04	9	146	2	C4087273
Disease	Hemolytic-uremic syndrome	CFH CFHR1	8.56e-04	9	146	2	cv:C0019061
Disease	complement component C8 measurement	CFH C8B	8.56e-04	9	146	2	EFO_0008094
Disease	leukocyte immunoglobulin-like receptor subfamily A member 5 measurement	CFH CFHR1	8.56e-04	9	146	2	EFO_0801766
Disease	Atypical Hemolytic Uremic Syndrome	CFH CFHR1	1.07e-03	10	146	2	C2931788
Disease	1,7-dimethylurate measurement	FOXP2 GRIK5	1.07e-03	10	146	2	EFO_0021512
Disease	adseverin measurement	CPN1 C1R	1.07e-03	10	146	2	EFO_0801358
Disease	f-box/LRR-repeat protein 4 measurement	CFH C1R	1.07e-03	10	146	2	EFO_0802538
Disease	autistic disorder (is_implicated_in)	FOXP2 RAPGEF4 GABRA4	1.18e-03	42	146	3	DOID:12849 (is_implicated_in)
Disease	Semantic-Pragmatic Disorder	FOXP2 SHANK3	1.30e-03	11	146	2	C0454655
Disease	Auditory Processing Disorder, Central	FOXP2 SHANK3	1.30e-03	11	146	2	C0751257
Disease	Language Delay	FOXP2 SHANK3	1.30e-03	11	146	2	C0023012
Disease	Language Development Disorders	FOXP2 SHANK3	1.30e-03	11	146	2	C0023014
Disease	hemopexin measurement	CFH CFHR1	1.30e-03	11	146	2	EFO_0008149
Disease	Speech Delay	FOXP2 SHANK3	1.30e-03	11	146	2	C0241210
Disease	diffuse plaque measurement	PSMF1 DOCK8 NPAS3 GRIK5 DNAJC6 SLC44A1 TENM4 MYO3B CHSY3 LNX1 ADGRA3	1.42e-03	758	146	11	EFO_0010699
Disease	Schizophrenia	ABCA1 FOXP2 SREBF2 NPAS3 GRIK5 F2 TRRAP SHANK3 TENM4 CGNL1 GNB3 GABRA4	1.52e-03	883	146	12	C0036341
Disease	Night blindness, congenital stationary, type 1	GPR179 GNB3	1.55e-03	12	146	2	C3501847
Disease	Night Blindness, Congenital Stationary, Type 1A	GPR179 GNB3	1.55e-03	12	146	2	C3495587
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)	GPR179 GNB3	1.55e-03	12	146	2	C1864877
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B	GPR179 GNB3	1.55e-03	12	146	2	C1850362
Disease	X-Linked Csnb	GPR179 GNB3	1.55e-03	12	146	2	C3711543
Disease	rheumatoid arthritis (implicated_via_orthology)	NCF1 IL6ST	1.55e-03	12	146	2	DOID:7148 (implicated_via_orthology)
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A	GPR179 GNB3	1.55e-03	12	146	2	C1848172
Disease	Adenoid Cystic Carcinoma	FOXP2 SRCAP GUCY1A1 ASPM	1.56e-03	100	146	4	C0010606
Disease	Kidney Failure, Chronic	ABCA1 NCF1 SREBF2	1.74e-03	48	146	3	C0022661
Disease	Cone-rod synaptic disorder, congenital nonprogressive	GPR179 GNB3	1.83e-03	13	146	2	C4041558
Disease	3-carboxy-4-methyl-5-propyl-2-furanpropanoate CMPF measurement	GRIK5 TENM4	1.83e-03	13	146	2	EFO_0021053
Disease	complement factor H-related protein 4 measurement	CFH CFHR1 ASPM	1.85e-03	49	146	3	EFO_0600091
Disease	membranous glomerulonephritis (biomarker_via_orthology)	CFH ABCA1	2.13e-03	14	146	2	DOID:10976 (biomarker_via_orthology)
Disease	level of Phosphatidylethanolamine (18:2_0:0) in blood serum	RAPSN ZNF512	2.13e-03	14	146	2	OBA_2045143
Disease	cholesterol to total lipids in large LDL percentage	ABCA1 RAPSN MYBPC3	2.72e-03	56	146	3	EFO_0022235
Disease	anthranilic acid measurement	MYO3B LNX1	2.79e-03	16	146	2	EFO_0010460
Disease	Blood Coagulation Disorders	F2 GGCX	2.79e-03	16	146	2	C0005779
Disease	IGF-1 measurement	RAPSN FOXP2 SREBF2 SRCAP SLC9A1 NSMAF ACOXL MYBPC3	3.06e-03	488	146	8	EFO_0004627
Disease	sleep duration, high density lipoprotein cholesterol measurement	ABCA1 RAPSN TMEM94 CGNL1	3.12e-03	121	146	4	EFO_0004612, EFO_0005271
Disease	Antibody Deficiency Syndrome	CFH C8B	3.15e-03	17	146	2	C0003257
Disease	Night blindness, congenital stationary	GPR179 GNB3	3.15e-03	17	146	2	C0339535
Disease	eicosapentaenoate EPA; 20:5n3 measurement	RAPSN GRIK5	3.15e-03	17	146	2	EFO_0021049
Disease	prostate carcinoma, type 2 diabetes mellitus	RAPSN RFX6 ZNF512	3.15e-03	59	146	3	EFO_0001663, MONDO_0005148
Disease	atrophic macular degeneration, age-related macular degeneration, wet macular degeneration	CFH CFHR1 ABCA1	3.30e-03	60	146	3	EFO_0001365, EFO_0004683, EFO_1001492
Disease	angina pectoris	CFH DHX38 GGCX GUCY1A1	3.51e-03	125	146	4	EFO_0003913
Disease	Age-related macular degeneration	CFH CFHR1	3.53e-03	18	146	2	cv:C0242383
Disease	Hypercholesterolemia, Familial	ABCA1 SREBF2	3.53e-03	18	146	2	C0020445
Disease	blood metabolite measurement	CRAT PPP1R16A	3.93e-03	19	146	2	EFO_0005664
Disease	coagulation factor measurement	CFH ASPM	4.36e-03	20	146	2	EFO_0004634
Disease	level of Phosphatidylcholine (18:1_20:4) in blood serum	ABCA1 RAPSN	4.80e-03	21	146	2	OBA_2045104
Disease	gestational age, birth measurement	RAPSN NPAS3	4.80e-03	21	146	2	EFO_0005112, EFO_0006921

Protein segments in the cluster

Peptide	Gene	Start	Entry
NTALRNLRYRRGIHK	ZNF280D	611	Q6N043
GYRIRDSELQKIHRA	ANKRD20A1	26	Q5TYW2
SLRKTDSRGYLVRSQ	NT5C1B	106	Q96P26
VNRRTLATLIGHLYR	ARAP3	1026	Q8WWN8
GYRIRDSELQKIHRA	ANKRD20A8P	26	Q5CZ79
GYRIRDSELQKIHRA	ANKRD20A4P	26	Q4UJ75
SKGHRASRLTVLREY	ADGRA3	1176	Q8IWK6
SSYRRVFHTLRGKGQ	GPR31	291	O00270
LKYRQGRTIILSTHH	ABCA1	1076	O95477
LRKAVQAHRGYTDRA	CRAT	496	P43155
SVKEVETYHRTRALR	ATAD2	61	Q6PL18
CKRGYRLSSRSHTLR	CFH	1201	P08603
YSRKVLTTIRSGHRA	DCAF6	81	Q58WW2
LVTLHGRSREQRYTK	DUS3L	461	Q96G46
NYSIRVERGLTLHLK	C1R	221	P00736
QKVRYRREHLSARQS	CAMSAP1	221	Q5T5Y3
ARHSIGYSIRRTSDK	CDH5	401	P33151
HLRKAAITIQSSYRR	ASPM	2456	Q8IZT6
HLRATVVSIQRRYRK	ASPM	2646	Q8IZT6
KLGLTIAIRYSHSRR	ACOXL	251	Q9NUZ1
HVNIRLVEVYRSTKR	RANBP2	166	P49792
YRSKGLQRELRAHVV	RAPSN	336	Q13702
IIAHASTTRLYLRKG	RAD51	291	Q06609
LLTTRRLGTRGHSKY	RFX6	176	Q8HWS3
HVNIRLVELYRSTKR	RGPD5	166	Q99666
HVNIRLVELYRSTKR	RGPD8	166	O14715
GQLAHYTKRVTITSR	H2BW2	101	P0C1H6
RRRFGTKRVHNNIVY	KIN	81	O60870
ARGLRATYHRLLDKV	MPC2	6	O95563
GYRIRDSELQKIHRA	ANKRD20A2P	26	Q5SQ80
VRRKLGTHYQITKNR	POGLUT1	81	Q8NBL1
SKTVYGDQSLHRELR	OTUD1	326	Q5VV17
YHTAIRRSESVKSRG	LAD1	411	O00515
SVTIRKSYTHIRRIV	KLHL6	601	Q8WZ60
GSSRRRIIHGTASYK	MAP7	281	Q14244
TRRSLRIYHINARKE	HSFX4	206	A0A1B0GTS1
ELLQRRLGKYEHSIS	ITIH5	161	Q86UX2
PALHKSRSTYDQRRE	GPR179	766	Q6PRD1
YGALREVSIHTVRAR	HERC1	4386	Q15751
ATRRRLVHYLKGREV	DCAF12L2	46	Q5VW00
LRSNYVLKGHRDVQR	PGLYRP1	161	O75594
IHQRSRKRLSQDAYR	NCF1	311	P14598
NVGAIRRRHSDKYNI	FOXP2	471	O15409
YTTVTKRSRRIRPTH	FGF18	191	O76093
ASHYGLTKDRKRRSQ	LNX1	131	Q8TBB1
LTKSGRSAHQVARYR	PKM	431	P14618
RTRRTLRGHLAKIYA	GNB2	46	P62879
RTRRTLRGHLAKIYA	GNB3	46	P16520
RTRRTLRGHLAKIYA	GNB4	46	Q9HAV0
RHVFGSRLQRIKTTV	GABRA4	476	P48169
SYLQGQRRTITHSRL	PRSS54	311	Q6PEW0
TRRSLRIYHINARKE	HSFX3	206	A0A1B0GWH4
PTTYKRRLQKRSSRH	ACAN	2506	P16112
RRLGERSLSSYVSVH	PCDHA10	496	Q9Y5I2
ITKGKHSYNSRTRER	PPIG	551	Q13427
HRRKGYSRLVALTLA	GLYATL3	221	Q5SZD4
HVNIRLVELYRSTKR	RGPD3	166	A6NKT7
HSRPNYTRKRDTRSE	CBY2	26	Q8NA61
GYRIRDSELQKIHRA	ANKRD20A3P	26	Q5VUR7
SKRHNYRELTLQRRG	IGSF10	716	Q6WRI0
TVHRTYLRGNLAESK	IL6ST	476	P40189
TRKRRYVASVSLHDR	KLHL12	316	Q53G59
TRVYSIGRSVEGRHL	CPN1	46	P15169
YDKSFEHRVRGVRRT	CPN1	226	P15169
RGELHEQYRRNTVLT	DOCK8	1906	Q8NF50
SVTRKRYAHLSARPA	FSCN1	146	Q16658
QEIHRRSARLRNTKY	GATAD1	86	Q8WUU5
YSGRHSQRTDKERRE	CPLANE1	2881	Q9H799
RTRRTLRGHLAKIYA	GNB1	46	P62873
LEKHYRRRNITVGLA	GLT6D1	66	Q7Z4J2
SRIIHLEGSYRSSKE	CGNL1	1131	Q0VF96
TRNTRTDAILLGHYR	FBXO9	326	Q9UK97
KNEHRGSRRVSYVGL	FCGBP	516	Q9Y6R7
RTRVVLRIGSAHSYA	GUSB	116	P08236
RLLDYSLHKERTGSN	CNPY3	106	Q9BT09
NGHQETKYRSGRIRV	CENPJ	1311	Q9HC77
LTAYRKELVGHARRV	CORO2A	121	Q92828
YHLRSTIGSRLQAKV	DNAJC6	301	O75061
VVHQLTRRAAYSLRV	ANGPT4	366	Q9Y264
YAVRKVHTIRGLIAR	CCHCR1	466	Q8TD31
KDGSRNITLRTHYIL	CEMIP2	166	Q9UHN6
LDYISLHRKGARSSI	IDUA	256	P35475
HRYSVRDARKTQLST	LYST	151	Q99698
LRGSVRQAVRLYHSV	MAPKBP1	1426	O60336
TLQDVRRIYKRRHGL	NSMAF	236	Q92636
SVNRLIRYHLGTVAK	SLC44A1	431	Q8WWI5
DYVHRIGRTARSTNK	DDX17	501	Q92841
KRGYRLSSRSHTLRT	CFHR1	301	Q03591
KDVESYIHRSGRTGR	DDX21	516	Q9NR30
RTVGYLRESIARNHL	ENPP7	221	Q6UWV6
TNYTLRILEKSRQGH	GRIK5	371	Q16478
RSSLEHGSDVYLLRK	GTF2IRD1	116	Q9UHL9
RTHYVDSVKRRFIIS	IGHV3-16	76	A0A0C4DH30
SRVTPVRSLRDQYHL	SBK3	31	P0C264
VRSLRDQYHLIRKLG	SBK3	36	P0C264
QSDRGKHYIRRTKRF	C8B	271	P07358
VKIQRHSSGLRIYDR	MAP3K19	1021	Q56UN5
HRTYKNSEELRSRIV	PSMF1	121	Q92530
STLRYADRAKRIVNH	KIF13A	341	Q9H1H9
SRLGLQEHVIRLYSK	MAP3K4	1431	Q9Y6R4
VRHGTVRYRSSALLA	MRPS31	36	Q92665
HVNIRLVELYRSTKR	RGPD4	166	Q7Z3J3
RQHLLAYLRERGKLS	RHNO1	216	Q9BSD3
DPSRNHRAYRLTVAK	RAPGEF4	901	Q8WZA2
VTLYHRLKRQTEQRV	SYNE1	4756	Q8NF91
LRTRRLGTRGNSKYH	RFX1	491	P22670
LRTRRLGTRGNSKYH	RFX3	236	P48380
AKYRSAHATRERIRV	NHLH2	76	Q02577
RVSLTQRTDLYRKQH	PPP1R16A	351	Q96I34
RRRGKTNHYQTTVEK	SLAMF1	261	Q13291
RHVRSSSLRVLVYQG	SHPRH	736	Q149N8
QASYRGHRSRKELRE	SPEGNB	36	A0A087WV53
RGHIYNSTSRIRNRK	MYCBP2	396	O75592
RAVYHLATRLVQTAR	MSH4	886	O15457
SGYKVIHITGRLRLR	NPAS3	281	Q8IXF0
RRRIQITILSYHSSI	ARHGAP5	826	Q13017
GQTRDVHIYRLISER	SRCAP	2156	Q6ZRS2
QYRLLHTTLSRKGLE	MRPL47	51	Q9HD33
HRRILASIEGSRFYT	EXTL1	111	Q92935
YTTISGQRRLRIHNL	SEC24D	751	O94855
SRKISELRYRTIQLH	CHSY3	411	Q70JA7
RRTASGRIQYLNHIT	SMURF2	166	Q9HAU4
TARRLLTHYVKVQGL	VPS51	571	Q9UID3
RRKSYLIDHQRTHTG	ZNF567	291	Q8N184
RHQRYSLETRVVLNG	nan	476	Q6ZTK2
RSHQHVKITYRDGRT	GGCX	406	P38435
LSYLTQHRRIHTGEK	ZNF695	336	Q8IW36
LTIRTQGLEYRTHRA	ZBTB7B	36	O15156
LTKVGRRLYTVRHRE	VPS13A	1956	Q96RL7
LYRGATQRKDSHVSL	ZSCAN32	236	Q9NX65
RLRLEKHISEQRAGY	TRPM5	201	Q9NZQ8
QTRGSSKFHIRRKRY	MMP16	106	P51512
RENYGRLRLITSSKH	MINPP1	171	Q9UNW1
EDRTKRLFRHYTVGS	SHANK3	541	Q9BYB0
IRLIEQARHATYGIR	TMEM94	1076	Q12767
GNEVSHYKRLARSTL	SCTR	331	P47872
RRTTHNIIEKRYRSS	SREBF2	331	Q12772
VRQTVRSHGVLGLYR	SLC25A1	71	P53007
HRKFTLRILYDQAGR	TENM4	1856	Q6N022
KTRQRLRSYNRHTLV	SLC9A1	641	P19634
GQNIRKDRHYRSARV	DHX38	101	Q92620
VALYRQRSRTALSKG	SUCO	641	Q9UBS9
NTRSYHRIVDIRDGK	ZBTB1	246	Q9Y2K1
KAYRISSSLRRHETT	ZNF443	456	Q9Y2A4
TLTRHRRVHTGEKSY	ZNF493	96	Q6ZR52
ENKKSYQTSVHRVRR	ZNF510	381	Q9Y2H8
DLLVRIGKHSRTRYE	F2	421	P00734
TLRQRHTEGAILYEK	SH2D3C	706	Q8N5H7
SRGTRNYKKTLLLRH	ZBTB10	296	Q96DT7
IKKLTGSTDRYDRRH	ZNF860	131	A6NHJ4
SVRTGRYRSILQLVK	PI15	126	O43692
SRITYLVRHQKIHTR	ZNF766	281	Q5HY98
VYTVLARRRGHVTQD	EFTUD2	846	Q15029
KTSHSVGRRARYIVK	GTF3C1	1311	Q12789
SRLTYGRHRREVQLQ	VSIG10L2	606	P0DP72
GRVQRRSAKIAVYHL	ZNF512	336	Q96ME7
VQKHNTAARRLYIRG	TRRAP	3506	Q9Y4A5
RYRSTLIRHQKVHTG	ZNF17	396	P17021
NRSSYLIRHKIIHTG	ZNF257	441	Q9Y2Q1
QRKTSRSRVYLHTLA	GUCY1A1	61	Q02108
VSIRRQGYSHRILFE	MYO3B	986	Q8WXR4
RRVHSGTYQVTVRIE	MYBPC3	1036	Q14896
VALRRRRHTFKGDYS	NECTIN1	376	Q15223