Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnucleotide receptor activity

P2RY13 PTAFR P2RX5

1.49e-0522443GO:0016502
GeneOntologyMolecularFunctionpurinergic nucleotide receptor activity

P2RY13 PTAFR P2RX5

1.49e-0522443GO:0001614
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR2 RYR3

2.84e-054442GO:0005219
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR2 RYR3

7.08e-056442GO:0048763
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC4A8 SLC30A5 SLC9C2

1.16e-0443443GO:0140828
GeneOntologyMolecularFunctionG protein-coupled purinergic nucleotide receptor activity

P2RY13 PTAFR

3.64e-0413442GO:0045028
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC4A8 SLC30A5 SLC9C2 SLC10A5 RYR2 RYR3

5.15e-04465446GO:0046873
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC4A8 SLC30A5 P2RX5 SLC9C2 SLC10A5 RYR2 RYR3

5.72e-04664447GO:0008324
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR2 RYR3

7.10e-0418442GO:0015278
GeneOntologyMolecularFunctionmetal cation:proton antiporter activity

SLC30A5 SLC9C2

1.61e-0327442GO:0051139
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC4A8 SLC30A5 P2RX5 SLC9C2 SLC10A5 RYR2 RYR3

1.61e-03793447GO:0015075
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RYR2 RYR3

2.12e-0331442GO:0099604
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC4A8 SLC30A5 SLC9C2 SLC10A5 RYR2 RYR3

2.39e-03627446GO:0022890
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

GPR141 P2RY13 PTAFR GRM3 P2RX5 IL1R1 ADGRL3 PECAM1 NPSR1

2.40e-031353449GO:0004888
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

RYR2 RYR3

2.40e-0333442GO:0005217
GeneOntologyMolecularFunctionantiporter activity

SLC4A8 SLC30A5 SLC9C2

3.48e-03138443GO:0015297
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

P2RX5 RYR2 RYR3

3.62e-03140443GO:0099094
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing N-glycosyl compounds

IL1R1 MACROD2

3.68e-0341442GO:0016799
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC4A8 SLC30A5 P2RX5 SLC9C2 SLC10A5 DISP1 RYR2 RYR3

3.84e-031180448GO:0022857
GeneOntologyMolecularFunctionhydrolase activity, acting on glycosyl bonds

IL1R1 PARG MACROD2

3.92e-03144443GO:0016798
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC4A8 SLC30A5 SLC9C2 SLC10A5

4.03e-03296444GO:0015291
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC4A8 SLC30A5 SLC9C2 SLC10A5

4.28e-03301444GO:0022853
GeneOntologyMolecularFunctionprotein-membrane adaptor activity

PRIMA1 RRAGC

4.42e-0345442GO:0043495
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC4A8 SLC30A5 SLC9C2 SLC10A5 RYR2 RYR3

6.05e-03758446GO:0015318
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC4A8 SLC9C2 SLC10A5

6.32e-03171443GO:0015081
GeneOntologyMolecularFunctiontransporter activity

SLC4A8 SLC30A5 P2RX5 SLC9C2 SLC10A5 DISP1 RYR2 RYR3

6.52e-031289448GO:0005215
GeneOntologyMolecularFunctiongrowth factor receptor binding

GLMN IL1R1 VAV2

6.52e-03173443GO:0070851
GeneOntologyBiologicalProcessneutrophil extravasation

IL1R1 PIK3CD PECAM1

7.23e-0618443GO:0072672
GeneOntologyBiologicalProcesspositive regulation of cellular extravasation

PTAFR IL1R1 PECAM1

1.78e-0524443GO:0002693
GeneOntologyBiologicalProcessresponse to purine-containing compound

HSP90B2P PTAFR P2RX5 RYR2 RYR3

2.68e-05166445GO:0014074
GeneOntologyBiologicalProcesscellular extravasation

PTAFR IL1R1 PIK3CD PECAM1

3.22e-0585444GO:0045123
GeneOntologyBiologicalProcesspurinergic nucleotide receptor signaling pathway

P2RY13 PTAFR P2RX5

4.73e-0533443GO:0035590
GeneOntologyBiologicalProcessresponse to ATP

HSP90B2P P2RX5 RYR3

8.47e-0540443GO:0033198
GeneOntologyBiologicalProcesspeptide hormone processing

HSP90B2P SLC30A5 DISP1

9.12e-0541443GO:0016486
GeneOntologyBiologicalProcesssignaling receptor ligand precursor processing

HSP90B2P SLC30A5 DISP1

1.29e-0446443GO:0140448
GeneOntologyBiologicalProcessregulation of cellular extravasation

PTAFR IL1R1 PECAM1

1.46e-0448443GO:0002691
GeneOntologyBiologicalProcessresponse to organophosphorus

HSP90B2P PTAFR P2RX5 RYR3

2.36e-04142444GO:0046683
GeneOntologyBiologicalProcesscellular response to caffeine

RYR2 RYR3

2.42e-0411442GO:0071313
GeneOntologyBiologicalProcessinsulin processing

HSP90B2P SLC30A5

2.90e-0412442GO:0030070
GeneOntologyBiologicalProcessprotein processing

HSP90B2P SLC30A5 MMP16 DISP1 NLRC4

3.40e-04285445GO:0016485
GeneOntologyBiologicalProcessG protein-coupled purinergic nucleotide receptor signaling pathway

P2RY13 PTAFR

3.42e-0413442GO:0035589
GeneOntologyBiologicalProcesscellular response to purine-containing compound

RYR2 RYR3

3.98e-0414442GO:0071415
GeneOntologyCellularComponentsmooth endoplasmic reticulum

HSP90B2P RYR2 RYR3

1.33e-0446453GO:0005790
DomainRyanrecept_TM4-6

RYR2 RYR3

1.62e-053442IPR009460
DomainRyR

RYR2 RYR3

1.62e-053442PF02026
DomainRyanodine_rcpt

RYR2 RYR3

1.62e-053442IPR003032
DomainRR_TM4-6

RYR2 RYR3

1.62e-053442PF06459
DomainRyan_recept

RYR2 RYR3

1.62e-053442IPR013333
DomainRIH_assoc

RYR2 RYR3

8.09e-056442PF08454
DomainRIH_assoc-dom

RYR2 RYR3

8.09e-056442IPR013662
DomainRIH_dom

RYR2 RYR3

8.09e-056442IPR000699
DomainIns145_P3_rcpt

RYR2 RYR3

8.09e-056442IPR014821
DomainRyanodine_recept-rel

RYR2 RYR3

8.09e-056442IPR015925
Domain-

RYR2 RYR3

8.09e-0564421.25.10.30
DomainRYDR_ITPR

RYR2 RYR3

8.09e-056442PF01365
DomainIns145_P3_rec

RYR2 RYR3

8.09e-056442PF08709
DomainMIR

RYR2 RYR3

2.41e-0410442PS50919
DomainMIR

RYR2 RYR3

2.41e-0410442PF02815
DomainMIR

RYR2 RYR3

2.41e-0410442SM00472
DomainMIR_motif

RYR2 RYR3

2.41e-0410442IPR016093
Pubmed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

ST6GAL1 GRM3 ARMC3 VAV2 RYR2 NPSR1

2.52e-0719946623382691
Pubmed

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

RYR2 RYR3

1.71e-06246221531043
Pubmed

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

RYR2 RYR3

1.71e-06246216678258
Pubmed

Alpha2,6-sialic acid on platelet endothelial cell adhesion molecule (PECAM) regulates its homophilic interactions and downstream antiapoptotic signaling.

ST6GAL1 PECAM1

1.71e-06246220048157
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

1.71e-0624628898078
Pubmed

PI3K p110δ is expressed by gp38(-)CD31(+) and gp38(+)CD31(+) spleen stromal cells and regulates their CCL19, CCL21, and LTβR mRNA levels.

PIK3CD PECAM1

1.71e-06246224009720
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

1.71e-06246214550562
Pubmed

Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.

RYR2 RYR3

1.71e-06246214985349
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR2 RYR3

5.13e-06346218403125
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR2 RYR3

5.13e-06346218434746
Pubmed

Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.

RYR2 RYR3

5.13e-06346229730765
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR2 RYR3

5.13e-0634629204703
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR2 RYR3

5.13e-0634627876312
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR2 RYR3

5.13e-06346221881589
Pubmed

NLRC4 inflammasome-mediated production of IL-1β modulates mucosal immunity in the lung against gram-negative bacterial infection.

IL1R1 NLRC4

5.13e-06346222547706
Pubmed

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR2 RYR3

5.13e-06346212213830
Pubmed

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR2 RYR3

5.13e-0634629242641
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR2 RYR3

5.13e-06346222948152
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR2 RYR3

5.13e-06346210788707
Pubmed

RYR2 proteins contribute to the formation of Ca(2+) sparks in smooth muscle.

RYR2 RYR3

5.13e-06346215024040
Pubmed

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR2 RYR3

5.13e-06346225239916
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR2 RYR3

5.13e-0634627621815
Pubmed

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR2 RYR3

5.13e-06346218643873
Pubmed

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR2 RYR3

5.13e-06346211159936
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR2 RYR3

5.13e-06346210473538
Pubmed

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR2 RYR3

5.13e-0634627959768
Pubmed

The organization of proteins in the human red blood cell membrane. A review.

RYR2 RYR3

5.13e-0634624600883
Pubmed

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

RYR2 RYR3

5.13e-0634627635066
Pubmed

Endoplasmic reticulum resident protein 44 (ERp44) deficiency in mice and zebrafish leads to cardiac developmental and functional defects.

HSP90B2P RYR2 PECAM1

6.93e-062846325332179
Pubmed

A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.

RYR2 RYR3

1.03e-05446218206662
Pubmed

Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases.

PARG MACROD2

1.03e-05446223474714
Pubmed

Ryanodine receptor calcium release channels: lessons from structure-function studies.

RYR2 RYR3

1.03e-05446223413940
Pubmed

Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.

RYR2 RYR3

1.03e-0544629384575
Pubmed

Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.

RYR2 RYR3

1.03e-0544629607712
Pubmed

Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.

RYR2 RYR3

1.03e-05446223482488
Pubmed

Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.

RYR2 RYR3

1.71e-05546233060591
Pubmed

Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.

RYR2 RYR3

1.71e-05546223918386
Pubmed

The genomic region encompassing the nephropathic cystinosis gene (CTNS): complete sequencing of a 200-kb segment and discovery of a novel gene within the common cystinosis-causing deletion.

ITGAE P2RX5

1.71e-05546210673275
Pubmed

Innate instruction of CD4+ T cell immunity in respiratory bacterial infection.

IL1R1 NLRC4

1.71e-05546222723524
Pubmed

IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis.

IL1R1 NLRC4

1.71e-05546226972847
Pubmed

Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.

RYR2 RYR3

1.71e-05546219011160
Pubmed

Significant role of IL-1 signaling, but limited role of inflammasome activation, in oviduct pathology during Chlamydia muridarum genital infection.

IL1R1 NLRC4

1.71e-05546222331066
Pubmed

Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.

RYR2 RYR3

2.56e-05646219549818
Pubmed

Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.

RYR2 RYR3

2.56e-05646226025922
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR2 RYR3

2.56e-05646223463619
Pubmed

Interaction of Ras with p110γ is required for thymic β-selection in the mouse.

PIK3CD VAV2

2.56e-05646221930962
Pubmed

FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.

RYR2 RYR3

2.56e-05646214592808
Pubmed

Inflammasome-dependent pyroptosis and IL-18 protect against Burkholderia pseudomallei lung infection while IL-1β is deleterious.

IL1R1 NLRC4

2.56e-05646222241982
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR2 RYR3

2.56e-05646220519450
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR2 RYR3

2.56e-05646225966694
Pubmed

HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.

RYR2 RYR3

2.56e-05646219009018
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR2 RYR3

2.56e-05646216844763
Pubmed

Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation.

PIK3CD VAV2

2.56e-05646218191593
Pubmed

The actin and tetraspanin networks organize receptor nanoclusters to regulate B cell receptor-mediated signaling.

PIK3CD VAV2

3.58e-05746223499492
Pubmed

IL-1β drives inflammatory responses to propionibacterium acnes in vitro and in vivo.

IL1R1 NLRC4

3.58e-05746224157462
Pubmed

Inflammasome activation and IL-1 signaling during placental malaria induce poor pregnancy outcomes.

IL1R1 NLRC4

3.58e-05746232181339
Pubmed

Francisella tularensis live vaccine strain folate metabolism and pseudouridine synthase gene mutants modulate macrophage caspase-1 activation.

IL1R1 NLRC4

3.58e-05746223115038
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR2 RYR3

3.58e-05746211860456
Pubmed

Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.

RYR2 RYR3

3.58e-05746220962236
Pubmed

Malarial hemozoin is a Nalp3 inflammasome activating danger signal.

IL1R1 NLRC4

4.77e-05846219652710
Pubmed

Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer.

IL1R1 NLRC4

4.77e-05846223696660
Pubmed

The transcription factor Th-POK negatively regulates Th17 differentiation in Vα14i NKT cells.

ITGAE IL1R1

4.77e-05846223034280
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR2 RYR3

4.77e-05846219033399
Pubmed

AIM2 inflammasome-derived IL-1β induces postoperative ileus in mice.

IL1R1 NLRC4

4.77e-05846231332247
Pubmed

The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury.

IL1R1 NLRC4

4.77e-05846227846608
Pubmed

Critical role of ASC inflammasomes and bacterial type IV secretion system in caspase-1 activation and host innate resistance to Brucella abortus infection.

IL1R1 NLRC4

4.77e-05846223460746
Pubmed

Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.

RYR2 RYR3

4.77e-05846211784029
Pubmed

Mycobacterium tuberculosis infection of dendritic cells leads to partially caspase-1/11-independent IL-1β and IL-18 secretion but not to pyroptosis.

IL1R1 NLRC4

7.65e-051046222911706
Pubmed

An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma.

IL1R1 PIK3CD

7.65e-051046221474346
Pubmed

Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration.

PIK3CD PECAM1

9.34e-051146218449193
Pubmed

Macrophages monitor tissue osmolarity and induce inflammatory response through NLRP3 and NLRC4 inflammasome activation.

IL1R1 NLRC4

1.12e-041246225959047
Pubmed

The Nlrp3 Inflammasome Suppresses Colorectal Cancer Metastatic Growth in the Liver by Promoting Natural Killer Cell Tumoricidal Activity.

IL1R1 NLRC4

1.12e-041246226384545
Pubmed

New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.

RYR2 RYR3

1.12e-041246219095005
Pubmed

NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis.

IL1R1 NLRC4

1.12e-041246221565393
Pubmed

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.

IL1R1 NLRC4

1.12e-041246221057511
Pubmed

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis.

IL1R1 NLRC4

1.32e-041346232758418
Pubmed

Inflammasomes Coordinate Pyroptosis and Natural Killer Cell Cytotoxicity to Clear Infection by a Ubiquitous Environmental Bacterium.

IL1R1 NLRC4

1.32e-041346226572063
Pubmed

Neutrophil elastase causes tissue damage that decreases host tolerance to lung infection with burkholderia species.

IL1R1 NLRC4

1.32e-041346225166912
Pubmed

Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.

IL1R1 NLRC4

1.32e-041346226008898
Pubmed

The G protein-coupled receptor repertoires of human and mouse.

GPR141 ADGRL3 NPSR1

1.60e-047946312679517
Pubmed

Vascular smooth muscle RhoA counteracts abdominal aortic aneurysm formation by modulating MAP4K4 activity.

MAP4K4 PECAM1

1.78e-041546236207400
Pubmed

Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to Aspergillus fumigatus hyphae.

PIK3CD VAV2

2.30e-041746221257963
Pubmed

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.

IL1R1 NLRC4

2.30e-041746222297845
Pubmed

The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7.

GLMN PECAM1

2.88e-041946222405651
Pubmed

Mfsd2a Is a Transporter for the Essential ω-3 Fatty Acid Docosahexaenoic Acid (DHA) in Eye and Is Important for Photoreceptor Cell Development.

PECAM1 CYP51A1

3.20e-042046227008858
Pubmed

HIV-1 Tat promotes Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6-induced angiogenesis and tumorigenesis by regulating PI3K/PTEN/AKT/GSK-3β signaling pathway.

PIK3CD PECAM1

4.25e-042346223301033
Pubmed

IKKβ Activation in the Fetal Lung Mesenchyme Alters Lung Vascular Development but Not Airway Morphogenesis.

NLRC4 PECAM1

4.25e-042346228923684
Pubmed

IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.

IL1R1 NLRC4

4.25e-042346229576451
Pubmed

Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor.

IL1R1 NLRC4

4.64e-042446234526512
Pubmed

Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo.

PTAFR IL1R1

6.79e-042946223708969
Pubmed

Large-scale concatenation cDNA sequencing.

ST6GAL1 OTULINL P2RX5 MMP16 RRAGC

9.01e-045684659110174
Pubmed

A "double adaptor" method for improved shotgun library construction.

ST6GAL1 OTULINL P2RX5 MMP16 RRAGC

9.44e-045744658619474
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

RYR2 RYR3

1.17e-033846230786075
CytobandEnsembl 112 genes in cytogenetic band chr7p14

GPR141 AOAH NPSR1

7.21e-04174463chr7p14
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR2 RYR3

8.53e-063312287
CoexpressionGSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_UP

ST6GAL1 ITGAE SBNO1 MAP4K4 NLRC4

1.27e-05172465M2945
CoexpressionGSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP

PTAFR SBNO1 PECAM1 AOAH CFAP46

2.62e-05200465M5418
CoexpressionSANSOM_APC_TARGETS_DN

CDR2 ST6GAL1 OTULINL ITGAE PIK3CD VAV2

4.16e-05366466M1432
CoexpressionFAN_EMBRYONIC_CTX_BIG_GROUPS_MICROGLIA

P2RY13 ZFHX3 ST6GAL1 OTULINL PTAFR AOAH

4.49e-05371466M39022
CoexpressionDESCARTES_FETAL_INTESTINE_MYELOID_CELLS

GPR141 P2RY13 PTAFR NLRC4 AOAH

5.09e-05230465M40210
CoexpressionDESCARTES_ORGANOGENESIS_WHITE_BLOOD_CELLS

GPR141 P2RY13 OTULINL PTAFR PIK3CD NLRC4 AOAH

9.15e-05615467MM3641
CoexpressionRIZKI_TUMOR_INVASIVENESS_3D_DN

GRM3 P2RX5 IL1R1 PIK3CD PECAM1

9.42e-05262465M11472
CoexpressionAtlasMyeloid Cells, DC.4+.MLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3

GPR141 SLC4A8 OTULINL PTAFR VAV2 ADGRL3 NLRC4

1.43e-05400437GSM538242_500
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

P2RY13 OTULINL PTAFR NLRC4 AOAH

9.30e-07172465f0e767a20d93e546ce278db67dbd779cc68af533
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZFHX3 MMP16 PRIMA1 ADGRL3 RYR2

9.57e-07173465cb6389536195443633adb06e5f1b7483530773d1
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

P2RY13 OTULINL PTAFR NLRC4 AOAH

9.85e-07174465f520b79d277e286c9bb5d091e6c94e7ec7e46699
ToppCellfacs-Skin-nan-18m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 ST6GAL1 PTAFR ITGAE PIK3CD

1.07e-0617746517065d37fd41f04f67282bee00365daa185e8355
ToppCellfacs-Skin-nan-18m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 ST6GAL1 PTAFR ITGAE PIK3CD

1.07e-061774656e45e1a5a894ca2e4ebc5cdb17fdf79e9e188185
ToppCellfacs-Skin-nan-18m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 ST6GAL1 PTAFR ITGAE PIK3CD

1.07e-061774659ff3a77c5c62c8a950c46ca22cd7bde425b84c9a
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RY13 OTULINL PTAFR NLRC4 AOAH

1.26e-0618346592d5a61b57851090eba558f19e2a7010043eff81
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KLHL6 P2RY13 PTAFR PIK3CD AOAH

1.52e-06190465773c55b9e28c2f77a5eb5f0adb0fa9862fb9611d
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RY13 OTULINL PTAFR NLRC4 AOAH

1.56e-0619146594c7da03e5264f4d73bb507ce339a935d90279a0
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KLHL6 P2RY13 OTULINL PTAFR AOAH

1.68e-06194465a062100ea6cd512a108f9036c259e0cd0f458563
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor3_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KLHL6 P2RY13 OTULINL PTAFR AOAH

1.72e-06195465c707885d092aedbbe14f51f7de4a5911c9214289
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor2_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KLHL6 P2RY13 OTULINL PTAFR AOAH

1.72e-06195465799992721369357484300fe218aff075154c3148
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

P2RY13 PIK3CD NLRC4 PECAM1 AOAH

1.72e-0619546510ce1b6961f10372d1f65388cbf3626a5fcd6840
ToppCellwk_15-18-Hematologic-Myeloid-DC3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

P2RY13 OTULINL PTAFR NLRC4 AOAH

1.77e-0619646520808c2ce010e4fcda092ecce94487f0afff733b
ToppCellParenchymal-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL6 PTAFR NLRC4 PECAM1 AOAH

1.90e-061994657ee2805fd9143eba11bf6832267b62189683608b
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--|Thalamus / BrainAtlas - Mouse McCarroll V32

GPR141 PTAFR NLRC4 AOAH

5.29e-06111464a1b7940c6fa0e5a58aa4798b604469d79f33fa44
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-|Thalamus / BrainAtlas - Mouse McCarroll V32

GPR141 PTAFR NLRC4 AOAH

5.29e-06111464d1ec8e8e9adb11511b4ef363cc6f99286e2cc842
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)|Thalamus / BrainAtlas - Mouse McCarroll V32

GPR141 PTAFR NLRC4 AOAH

5.29e-06111464567e5ac2c78d45db207067f0f152bb24ed048c50
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)|Thalamus / BrainAtlas - Mouse McCarroll V32

GPR141 PTAFR NLRC4 AOAH

5.29e-06111464fd7aa25e83a0d762969e3966a658652da40c490e
ToppCellThalamus-Hematopoietic-MACROPHAGE|Thalamus / BrainAtlas - Mouse McCarroll V32

GPR141 PTAFR NLRC4 AOAH

5.29e-06111464d48561078c387ac856c1c30e3d7a3e75ebde942e
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-C1ql2-Excitatory_Neuron.Slc17a7.C1ql2-Cck_(Dentate_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

SPINT4 ITGAE P2RX5 IL1R1

9.59e-0612946408ecebb7f09d105dfdfd2191fc310910d3baec0f
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTULINL PTAFR NLRC4 AOAH

1.65e-051484647c7c87b57aa16f8b91698489df39ace5a3a53df8
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P2RY13 ZFHX3 ST6GAL1 PTAFR

1.78e-051514642f9b3e14c2fa6e2b1976ca6ab2031b63bf5e3e64
ToppCellfacs-MAT-Fat-18m-Myeloid-myeloid_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 P2RY13 PTAFR AOAH

2.24e-05160464bd5fa7959bfe81011b8d798535b73ea1eee008b3
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KLHL6 P2RY13 ST6GAL1 PTAFR

2.41e-05163464a6e272e043859858084b8d4d96fa4ff9e6eca454
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 OTULINL DISP1 AOAH

2.58e-0516646463dc58864268b4e7779e4c45155022556fc634f9
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 OTULINL PIK3CD AOAH

2.58e-05166464bf6c35c3e67ef4ca98a38926c6f7923ecca0508a
ToppCellfacs-Lung-EPCAM-18m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 OTULINL PIK3CD AOAH

2.58e-05166464433128b7d964b32faa0bf437a02facc819ab1405
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P2RY13 ZFHX3 ST6GAL1 PTAFR

2.65e-05167464942134bbabe9972fae80cbc4ed4e94da52f55dc3
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P2RY13 OTULINL ARMC3 NLRC4

2.65e-05167464f5bffa77061baec0ba87bd688a047595f32534db
ToppCelldroplet-Lung-LUNG-30m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A8 P2RX5 VAV2 PRIMA1

2.71e-051684640e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCelldroplet-Liver-Npc-18m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 OTULINL ITGAE PJVK

2.71e-05168464ce5e92a1df3acfa5cd8d5a134e4af231dc592a13
ToppCelldroplet-Liver-Npc-18m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 OTULINL ITGAE PJVK

2.71e-0516846422c89d4eb44573f6301069ec7ca7cbd0dd958403
ToppCellfacs-Lung-18m-Hematologic-myeloid-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR141 OTULINL PIK3CD AOAH

2.71e-051684640ffad93ba2fb5d4cfda2c13011059555475dcfc8
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR141 DISP1 NLRC4 AOAH

2.71e-05168464c3d2d573f21350a4a674faff30b06ff644d00ac3
ToppCellfacs-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR141 OTULINL PIK3CD AOAH

2.71e-05168464ab1fb9b2cc7c5853b7fbd373e1784a9a31f96d38
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KLHL6 P2RY13 ZFHX3 ST6GAL1

2.77e-051694640867528101767fc65e93b3561480bf830c50368d
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Lymphocytic-mature_NK_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTULINL ARMC3 PIK3CD AOAH

2.90e-05171464562fc8a422615dbbece67ea49740f0c09bdb9ae3
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR141 TMEM244 PIK3CD AOAH

2.90e-05171464187b396059f8802265f54bad2b4882cebb809419
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

PRIMA1 ADGRL3 RYR2 RYR3

3.04e-05173464a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellfacs-Heart-LA-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P2RY13 OTULINL PTAFR AOAH

3.11e-0517446430c083fe4711735e83dccfd00fcd746ae673d353
ToppCellfacs-Heart-LA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P2RY13 OTULINL PTAFR AOAH

3.11e-0517446446d19c1144fff19be682b7ba59d4c3e014f79e15
ToppCellfacs-Heart-LA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P2RY13 OTULINL PTAFR AOAH

3.11e-051744641802a52552256d1e25d8b328ba62dcfe41671900
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KLHL6 ST6GAL1 MMP16 PECAM1

3.18e-051754642e54961846c65b185d9bd6e305dd81205579d890
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

P2RY13 OTULINL NLRC4 AOAH

3.18e-05175464d983e80eeb11f341c564ea684e2b0b585a90ae58
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KLHL6 ST6GAL1 MMP16 PECAM1

3.18e-05175464efa6a05f7417d46141b6e635f258c126b7a03aa1
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

P2RY13 OTULINL PTAFR AOAH

3.25e-05176464adb679e69c0c17f0caee4c141bac55d03c963012
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

P2RY13 OTULINL PTAFR AOAH

3.32e-05177464ab92ffc9624850a50c88e6b8f3a517ff2251ff15
ToppCell3'-Adult-SmallIntestine-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KLHL6 ST6GAL1 P2RX5 PIK3CD

3.39e-05178464da1695a936dbe3ca9ee3fb28ceb60511c47b35f8
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC4A8 ARMC3 SLC9C2 CFAP46

3.39e-051784643b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell3'-Adult-SmallIntestine-Hematopoietic-B_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KLHL6 ST6GAL1 P2RX5 PIK3CD

3.39e-05178464580fc1d45b82010c665a313b2e7a21e0116819ef
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RY13 PTAFR NLRC4 AOAH

3.47e-05179464409364d916c5e7e2291284cc74351d8f8a8447ac
ToppCellControl-Myeloid-Monocytes,_Macrophages|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR141 P2RY13 PTAFR AOAH

3.47e-05179464a79a244bf8ecc333d034b2eb2de554d3310ca6de
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KLHL6 GPR141 PTAFR AOAH

3.47e-05179464716856b2c7c660bf5ce00e63efeda6ed121f2baa
ToppCell5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KLHL6 PTAFR NLRC4 AOAH

3.47e-051794641016af3d61a9276a792629f8b1a28a93038e29c1
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL6 ITGAE PIK3CD AOAH

3.47e-05179464cb880ef40c203c8bd16c4f69a70cf59f97ebbffd
ToppCellControl-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR141 P2RY13 PTAFR AOAH

3.47e-05179464c4ff8b191ed0f6dc2dd784869f6f2c62e170a7db
ToppCell5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR141 P2RY13 NLRC4 AOAH

3.47e-05179464ae9d90a4eac2cfa545a764df84914c5801544278
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Hematologic|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL6 ITGAE PIK3CD AOAH

3.47e-05179464686b9f745d290ca686b42d9505e9792c78667e6e
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

P2RY13 OTULINL NLRC4 AOAH

3.47e-05179464fae869fb0a91428481bf8a9c111dcc639e2b4278
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL6 ITGAE PIK3CD AOAH

3.47e-051794641eb004e1a17e1f1e4337e0581e547c0f5a965e68
ToppCelldroplet-Mammary_Gland-nan-18m-Lymphocytic-T_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL6 SLC4A8 ITGAE PIK3CD

3.47e-0517946448ee1c6d6402c7f5d6578f8de14da6f55aa952d6
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR141 P2RY13 PTAFR NLRC4

3.55e-051804647af90f0e7ca001bf1fe5c860ee54c4cc8eb483bf
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

ZFHX3 MMP16 ADGRL3 RYR2

3.55e-05180464d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellnormal_Lymph_Node-Myeloid_cells-Pleural_Mac|normal_Lymph_Node / Location, Cell class and cell subclass

GPR141 P2RY13 PTAFR AOAH

3.62e-05181464921e917f83105896ad8918dc134b871708024021
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR141 P2RY13 PTAFR AOAH

3.62e-0518146408bc6fe2a11d31a7e5e4a4552b04c0ebc2aefc59
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KLHL6 GPR141 PTAFR AOAH

3.62e-05181464090e89b506d945e123e647d08947e9649a65ce7c
ToppCellControl-Myeloid|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR141 P2RY13 PTAFR AOAH

3.62e-0518146425170e5285996cc80337d5f86a0255569861ae77
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P2RY13 ST6GAL1 OTULINL PTAFR

3.70e-05182464c6b3762ccec326f057819f75fa7fac0145fb7d54
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFHX3 PTAFR VAV2 RYR3

3.70e-0518246472e65a23cd36085bc880087d3cae92395de918a1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFHX3 PTAFR VAV2 RYR3

3.70e-0518246405c167158815bf25d509df59ab386e1990712765
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ZFHX3 SLC4A8 RYR2 RYR3

3.95e-051854647dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RY13 PTAFR PIK3CD AOAH

3.95e-05185464e592c27f711d13bfc6546893acaab4c8600b0be1
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IL1R1 MMP16 ADGRL3 PECAM1

4.03e-0518646492092f11ecce22c14f244e42c499af0822977e6f
ToppCellwk_08-11-Hematologic-Myeloid-S100A12-lo_cla._mono.|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GPR141 P2RY13 PTAFR AOAH

4.03e-05186464be50f5c7f32b3126442ebff1e7d38aa78b6e4e71
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

P2RY13 ZFHX3 ST6GAL1 AOAH

4.11e-051874645ce7cf02990465b6f793205e4be07e8337b3570a
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

P2RY13 ZFHX3 ST6GAL1 AOAH

4.11e-0518746417a37fc3a1d62fef3137e5ff26a84c0b8c80e124
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid-Micro|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

P2RY13 ZFHX3 ST6GAL1 AOAH

4.11e-051874641b0eb29394040555516677b9de75c15e769c4c53
ToppCellIPF-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

KLHL6 ST6GAL1 MAP4K4 VAV2

4.11e-05187464af1327559f7e01bec070881cae52834917c3da65
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

P2RY13 ZFHX3 ST6GAL1 AOAH

4.11e-0518746411c773cf3dc1e725b7e4d8edd676c8a94a231d2a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

P2RY13 ST6GAL1 PTAFR AOAH

4.20e-05188464c65fb9a3c910dd6166853f4f3a2f2c2411ccf03b
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

ADGRL3 RYR2 RYR3 MACROD2

4.20e-0518846434e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_migrating_dendritic_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KLHL6 P2RY13 PTAFR AOAH

4.20e-051884648fc15c8b78fdd1a578e34325011bc5a87a8aab31
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 P2RY13 PIK3CD AOAH

4.20e-051884640d7296ad26e97ad91c6927a6cfe4e6e70a74c5a6
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

P2RY13 ZFHX3 ST6GAL1 AOAH

4.29e-05189464389ccb68acb82893709f256315111470cf4beed3
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

P2RY13 ZFHX3 ST6GAL1 AOAH

4.29e-0518946458465b9407fbce91cca8f199950d6e0054c38fbc
ToppCell3'-Adult-LargeIntestine-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RY13 SLC4A8 NLRC4 AOAH

4.29e-05189464b491204cf38dc80a2583e3082a82dda8d77b3fc4
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_macrophage|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KLHL6 P2RY13 PTAFR AOAH

4.29e-05189464a438c64a893d43f781ede42e1c7b615b74dc76ef
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

P2RY13 ZFHX3 ST6GAL1 AOAH

4.29e-051894647ac78441a15a82218deaafd47accff2ea5c8de20
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor2_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KLHL6 P2RY13 PTAFR AOAH

4.38e-05190464081b7bc07b6e5685e8a91b9ae6c1141623723700
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 P2RY13 PIK3CD AOAH

4.38e-051904647c402aa47f1bd7decacc366c1ed1a37e39b95c73
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

KLHL6 ST6GAL1 MAP4K4 VAV2

4.38e-051904641e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte1_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KLHL6 P2RY13 PTAFR AOAH

4.47e-05191464367d300da3925e0a329271b5f19483a37265a878
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-cDC2|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR141 P2RY13 PTAFR AOAH

4.47e-05191464a898153490fb9e8c4331c5dce63dbfb5185bccf2
ToppCellkidney_cells-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 P2RY13 OTULINL AOAH

4.56e-05192464ae7513fde6e33a1908c2777cdb1d1e4ead1bcb2f
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P2RY13 ST6GAL1 OTULINL PTAFR

4.56e-05192464314d94d676d13f4ca0eea8ba222c7eb00946849c
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_proliferating_myeloid_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KLHL6 P2RY13 PTAFR AOAH

4.56e-051924647e7383093efaadceadd4d1f900c2d39cd690102e
ToppCell367C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DISP1 ADGRL3 PECAM1 CFAP46

4.65e-051934645c6b03d6d98aa873fda1a201d44a912246bb5a92
ToppCellPCW_07-8.5-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_neutrophils_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KLHL6 PTAFR NLRC4 AOAH

4.65e-05193464c9e3fefa8d68d0e2b954f85ce37813185ff98d84
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P2RY13 ST6GAL1 OTULINL PTAFR

4.65e-05193464fc2eb6a7b4f1e687bf37e59e3cd52b14f99ffea4
DrugAC1L1IZE

P2RY13 P2RX5 RYR2 RYR3 CYP51A1

5.93e-06131455CID000004799
Drug2-hydroxycarbazole

RYR2 RYR3

1.14e-053452CID000093551
Drugcis-diammineplatinum(II

RYR2 RYR3

1.14e-053452CID000159790
Drug2-hydroxyheptanoic acid

RYR2 RYR3

1.14e-053452CID002750949
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR2 RYR3

1.14e-053452CID005748312
Drug8N3-cADPR

RYR2 RYR3

1.14e-053452CID000127713
Drugaminodantrolene

RYR2 RYR3

1.14e-053452CID009570289
Drugrhod-2

GRM3 RYR3 CYP51A1

2.28e-0528453CID000123669
DrugCyclic ADP-Ribose

RYR2 PARG

2.29e-054452ctd:D036563
DrugPCB74

RYR2 RYR3

2.29e-054452CID000036218
Drug148504-47-6

RYR2 RYR3

2.29e-054452CID006444275
DrugSC 38249

RYR2 RYR3

2.29e-054452CID000134834
DrugAC1L1U7A

RYR2 RYR3

2.29e-054452CID000035682
DrugLOPAC

CDR2 RYR2 RYR3

2.82e-0530453CID000062696
Druggadolinium

SLC30A5 GRM3 RYR2 RYR3 PECAM1

4.46e-05199455CID000023982
DrugMBED

RYR2 RYR3

5.70e-056452CID000129958
Drugchloro-m-cresol

RYR2 RYR3

5.70e-056452CID000012008
DrugAC1O528X

RYR2 RYR3

5.70e-056452CID006475857
DrugNSC114784

RYR2 RYR3

5.70e-056452CID000419425
DrugAzumoleno

RYR2 RYR3

7.97e-057452CID000056259
DrugBr2BAPTA

RYR2 RYR3

7.97e-057452CID003081001
Drug[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate

RYR2 RYR3

7.97e-057452CID009547999
Drugcaffeine

P2RY13 CDR2 GRM3 P2RX5 RYR2 RYR3 CYP51A1

1.08e-04562457CID000002519
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR2 RYR3

6.82e-063452DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR2 RYR3

6.82e-063452DOID:8545 (implicated_via_orthology)
Diseaseinterleukin 1 receptor-like 2 measurement

IL1R1 MAP4K4

8.13e-059452EFO_0008169
Diseasecommon carotid intimal medial thickness

MMS22L RYR3 MACROD2

1.48e-0467453EFO_0004860
DiseaseS-6-hydroxywarfarin measurement

ZFHX3 ITGAE ARMC3 VAV2 MACROD2

2.38e-04368455EFO_0803326
DiseaseST2 protein measurement

IL1R1 MAP4K4

4.69e-0421452EFO_0010599
Diseasesuicidal ideation

ZFHX3 CFAP46

8.99e-0429452EFO_0004320
Diseaserisk-taking behaviour

ZFHX3 MMS22L PRIMA1 ADGRL3 RYR2 MACROD2

1.02e-03764456EFO_0008579
Diseaseserum IgG glycosylation measurement

ST6GAL1 GRM3 ARMC3 VAV2 RYR2

1.17e-03523455EFO_0005193
Diseaseheart disease (implicated_via_orthology)

PIK3CD RYR2

1.54e-0338452DOID:114 (implicated_via_orthology)
Diseaseepilepsy

GRM3 ADGRL3

1.80e-0341452EFO_0000474
Diseasehigh grade glioma (implicated_via_orthology)

ST6GAL1 PIK3CD

2.07e-0344452DOID:3070 (implicated_via_orthology)
Diseasesevere acute respiratory syndrome (is_marker_for)

IL1R1 PECAM1

2.35e-0347452DOID:2945 (is_marker_for)
Diseaselung adenocarcinoma (is_implicated_in)

ZFHX3 MAP4K4

2.56e-0349452DOID:3910 (is_implicated_in)
Diseasehepatocellular carcinoma (is_implicated_in)

ZFHX3 MAP4K4 RYR3

2.67e-03181453DOID:684 (is_implicated_in)
Diseaseresponse to cisplatin, platinum measurement

MMS22L VAV2

2.98e-0353452EFO_0010154, GO_0072718
Diseasealcohol use disorder (implicated_via_orthology)

PIK3CD RYR2 RYR3

3.29e-03195453DOID:1574 (implicated_via_orthology)
Diseaseatopic asthma

MICA OTULINL MAP4K4

3.48e-03199453EFO_0010638
Diseasecolorectal health

ZFHX3 ARMC3 RYR2

3.58e-03201453EFO_0008460
Diseaseresponse to cranial radiation therapy, short-term memory

IL1R1 MACROD2

3.81e-0360452EFO_0004335, EFO_0010950
Diseaseword reading

ZFHX3 MMS22L

4.45e-0365452EFO_0005300

Protein segments in the cluster

PeptideGeneStartEntry
ILVILCTVYAFKTRK

GRM3

746

Q14832
FIFIFHCVLQKKVRK

ADGRL3

1096

Q9HAR2
SRFCLLYDNVKVKKL

CFAP46

601

Q8IYW2
ILAKACEAIYKFALK

ARMC3

41

Q5W041
FEKVLPCIVIKFRYL

DISP1

706

Q96F81
AFLKKCVCYIRKIAN

NWD2

251

Q9ULI1
VTRYLIFFKCKDKVE

GPR141

111

Q7Z602
IFFKCKDKVEFYRKL

GPR141

116

Q7Z602
FVIIIFYVRCCKKKT

MICA

321

Q29983
KLFLKTTCYLVIDKF

AOAH

76

P28039
KKSDYIKLYVRCVFI

HSP90B2P

61

Q58FF3
YKVVKYERIKFLVIA

MAP4K4

1026

O95819
FCNDLKEKYEKRIII

KLHL6

101

Q8WZ60
CKALTKFKFVFFLRL

NLRC4

191

Q9NPP4
KAIKYSIIIILAFIC

NPSR1

271

Q6W5P4
VKEIRCLGRKYEKIF

CT45A10

131

P0DMU9
YTIFLCILAKVVKKA

MMS22L

481

Q6ZRQ5
KKCIVQVIRKSYLEY

MMS22L

1066

Q6ZRQ5
VILVILFKCGFFKRK

ITGAE

1141

P38570
LKTLFCYFRRVTEKK

PARG

676

Q86W56
LIIAAKCYFLRKAKA

PECAM1

616

P16284
GYSLEVKIKVFRLFK

OTULINL

306

Q9NUU6
IYIFLCKKFTEKLPC

P2RY13

316

Q9BPV8
EYKALFKEIFSCIKK

CDR2

421

Q01850
YINLFVEKYLKVCKT

LINC00032

46

P0C843
FFLARDKTLQKKCYL

CYP51A1

331

Q16850
FKYLCIASKVKRVVQ

SBNO1

601

A3KN83
YCLKVPLVIFKREKE

RYR2

4591

Q92736
CSVFIYKIFKIDIVL

IL1R1

351

P14778
FCDLVLIYLIKKREF

P2RX5

331

Q93086
FCVFLEVDFKIYKKK

MACROD2

221

A1Z1Q3
SKRKVYFLIFDLLVK

GLMN

81

Q92990
VIRAFVKCTKARYLK

MRPL20

46

Q9BYC9
LYLKEVTKFLALVCI

RRAGC

326

Q9HB90
ARLYPCKKFNEIKIF

PTAFR

41

P25105
VIYCFLTKKFRKHLT

PTAFR

291

P25105
FLTVLVIICYKAIKR

PRIMA1

106

Q86XR5
LKKKFSCCVLVFLLF

ST6GAL1

6

P15907
VLVFEKILFKFCKDY

SLC4A8

541

Q2Y0W8
LVYKAKKRCIFFLQD

SLC10A5

416

Q5PT55
KVVLQKFLLCVILFY

TMEM244

11

Q5VVB8
CLLVLVYTVFQFKRK

MMP16

576

P51512
LVVKKKRCFLFPRYK

PJVK

36

Q0ZLH3
YCLKVPLVVFKREKE

RYR3

4496

Q15413
FKLKIEREVACVAKY

SPINT4

81

Q6UDR6
CFALYAVIEKAKKAR

PIK3CD

391

O00329
KYIVLLCFTKFLKAV

SLC30A5

31

Q8TAD4
KFKNVLTFLEYCIEK

SLC9C2

571

Q5TAH2
YLFLFDKVVIVCKRK

VAV2

426

P52735
KKCSLVFQRIFDLIK

ZFHX3

2331

Q15911