Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of chromatin

H3Y2 H1-10 H1-8 H3C1 H3-3A H3-4 H3-7 H3C15

2.98e-10100558GO:0030527
GeneOntologyMolecularFunctionstructural molecule activity

H3Y2 H1-10 H1-8 H3C1 MACF1 H3-3A H3-4 H3-7 H3C15

6.75e-04891559GO:0005198
GeneOntologyMolecularFunctionprotein heterodimerization activity

H3Y2 H3C1 H3-3A H3-4 H3-7 H3C15

7.68e-04398556GO:0046982
GeneOntologyMolecularFunctionnucleosomal DNA binding

H1-10 H1-8 H3-3A

8.36e-0467553GO:0031492
GeneOntologyMolecularFunction1-phosphatidylinositol-3-kinase regulator activity

PIK3R5 SOCS7

8.72e-0416552GO:0046935
GeneOntologyMolecularFunctionchromatin DNA binding

H1-10 H1-8 H3-3A KDM6A

1.15e-03167554GO:0031490
GeneOntologyMolecularFunctionmicrotubule binding

NF1 APC2 MAST1 MACF1 FHDC1

1.56e-03308555GO:0008017
GeneOntologyBiologicalProcessnucleosome assembly

H1-10 H1-8 H3C1 H3-3A H3-4 H3C15

6.17e-07122526GO:0006334
GeneOntologyBiologicalProcessnucleosome organization

H1-10 H1-8 H3C1 H3-3A H3-4 H3C15

1.50e-06142526GO:0034728
GeneOntologyBiologicalProcessprotein-DNA complex assembly

H1-10 H1-8 H3C1 CENPV H3-3A H3-4 H3C15

2.89e-06249527GO:0065004
GeneOntologyBiologicalProcesschromatin organization

H1-10 H1-8 H3C1 MKI67 EHMT1 CENPV CHD9 H3-3A H3-4 H3C15 KDM6A

1.15e-058965211GO:0006325
GeneOntologyBiologicalProcesschromatin remodeling

H1-10 H1-8 H3C1 EHMT1 CENPV CHD9 H3-3A H3-4 H3C15 KDM6A

1.36e-057415210GO:0006338
GeneOntologyBiologicalProcessprotein-DNA complex organization

H1-10 H1-8 H3C1 MKI67 EHMT1 CENPV CHD9 H3-3A H3-4 H3C15 KDM6A

3.16e-059995211GO:0071824
GeneOntologyBiologicalProcesspericentric heterochromatin formation

CENPV H3-3A

9.29e-056522GO:0031508
GeneOntologyBiologicalProcesschromosome condensation

H1-10 H1-8 H3-3A

2.41e-0448523GO:0030261
GeneOntologyBiologicalProcessprotein K11-linked deubiquitination

OTUD3 VCPIP1

2.77e-0410522GO:0035871
GeneOntologyCellularComponentnucleosome

H3Y2 H1-10 H1-8 H3C1 H3-3A H3-4 H3-7 H3C15

2.37e-09138548GO:0000786
DomainHISTONE_H3_1

H3C1 H3-3A H3-4

7.49e-077533PS00322
DomainH3

H3C1 H3-3A H3-4

1.20e-068533SM00428
DomainHISTONE_H3_2

H3C1 H3-3A H3-4

1.20e-068533PS00959
DomainHistone_H3/CENP-A

H3C1 H3-3A H3-4

1.20e-068533IPR000164
DomainHistone

H3C1 H3-3A H3-4

5.38e-0456533PF00125
DomainHistone_H2A/H2B/H3

H3C1 H3-3A H3-4

5.38e-0456533IPR007125
DomainH15

H1-10 H1-8

6.04e-0413532SM00526
DomainLinker_histone

H1-10 H1-8

6.04e-0413532PF00538
DomainOTU

OTUD3 VCPIP1

6.04e-0413532PF02338
DomainH15

H1-10 H1-8

6.04e-0413532PS51504
DomainHistone_H1/H5_H15

H1-10 H1-8

7.03e-0414532IPR005818
DomainOTU

OTUD3 VCPIP1

8.10e-0415532PS50802
DomainOTU_dom

OTUD3 VCPIP1

8.10e-0415532IPR003323
Domain-

H3C1 H3-3A H3-4

9.90e-04695331.10.20.10
DomainHistone-fold

H3C1 H3-3A H3-4

1.69e-0383533IPR009072
DomainAAA

FIGNL2 WRNIP1

4.18e-0334532PS00674
DomainFHA_dom

RASIP1 MKI67

4.68e-0336532IPR000253
Domain-

RASIP1 MKI67

4.68e-03365322.60.200.20
DomainAAA

FIGNL2 WRNIP1

9.57e-0352532PF00004
DomainSMAD_FHA_domain

RASIP1 MKI67

9.57e-0352532IPR008984
PathwayKEGG_MEDICUS_VARIANT_IGH_MMSET_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION

H3C1 H3-3A H3-4 H3C15

1.07e-0719344M47442
PathwayWP_EFFECT_OF_PROGERIN_ON_GENES_INVOLVED_IN_PROGERIA

H3C1 SREBF1 H3-3A H3C15

1.76e-0637344M39756
PathwayREACTOME_MATERNAL_TO_ZYGOTIC_TRANSITION_MZT

H1-8 H3C1 H3-3A H3C15 KDM6A

1.29e-05128345M48019
PathwayWP_HISTONE_MODIFICATIONS

H3C1 EHMT1 H3-3A H3C15

1.72e-0565344M39374
PathwayKEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS

H3Y2 H3C1 H3-3A H3-4 H3C15

1.92e-05139345M4741
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_THE_HUMAN_SILENCING_HUB_HUSH_COMPLEX

H3C1 EHMT1 H3-3A H3C15

2.31e-0570344M48261
PathwayREACTOME_CHROMATIN_MODIFICATIONS_DURING_THE_MATERNAL_TO_ZYGOTIC_TRANSITION_MZT

H3C1 H3-3A H3C15 KDM6A

2.31e-0570344M48028
PathwayREACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES

H3C1 H3-3A H3-4 H3C15

2.73e-0573344M27166
PathwayWP_KLEEFSTRA_SYNDROME

EHMT1 H3-3A KDM6A

4.49e-0529343M48076
PathwayREACTOME_MEIOTIC_RECOMBINATION

H3C1 H3-3A H3-4 H3C15

5.70e-0588344M1011
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

H3C1 H3-3A H3-4 H3C15

6.50e-0591344M27101
PathwayWP_FBXL10_ENHANCEMENT_OF_MAPERK_SIGNALING_IN_DIFFUSE_LARGE_BCELL_LYMPHOMA

H3C1 H3-3A H3C15

6.66e-0533343M39800
PathwayREACTOME_CELLULAR_SENESCENCE

H3C1 EHMT1 H3-3A H3-4 H3C15

1.01e-04197345M27188
PathwayREACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP

H3C1 EHMT1 H3-3A H3C15

1.41e-04111344M27187
PathwayWP_SENESCENCEASSOCIATED_SECRETORY_PHENOTYPE_SASP

H3C1 EHMT1 H3-3A H3C15

1.46e-04112344M48334
PathwayREACTOME_GAP_JUNCTION_TRAFFICKING_AND_REGULATION

GJA3 MYO6 DAB2

1.59e-0444343MM14606
PathwayREACTOME_MEIOSIS

H3C1 H3-3A H3-4 H3C15

1.90e-04120344M529
PathwayREACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

H3C1 H3-3A H3C15 KDM6A

2.03e-04122344M29689
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

H3C1 H3C15 KDM6A

2.33e-0450343M27232
PathwayREACTOME_GAP_JUNCTION_TRAFFICKING_AND_REGULATION

GJA3 MYO6 DAB2

2.47e-0451343M26972
PathwayREACTOME_GAP_JUNCTION_DEGRADATION

MYO6 DAB2

3.06e-0411342MM14732
PathwayREACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

H3C1 EHMT1 H3-3A H3C15 KDM6A

3.31e-04254345M27131
PathwayREACTOME_MITOTIC_PROPHASE

H3C1 H3-3A H3-4 H3C15

3.62e-04142344M27660
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS

H3C1 EHMT1 H3-3A H3C15

3.62e-04142344M48257
PathwayREACTOME_GAP_JUNCTION_DEGRADATION

MYO6 DAB2

3.67e-0412342M15243
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

GTF2F1 H3C1 H3-3A H3C15

4.34e-04149344M27888
PathwayREACTOME_DNA_METHYLATION

H3C1 H3-3A H3C15

4.83e-0464343M27429
PathwayREACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3

H3C1 H3-3A H3C15

5.29e-0466343M27488
PathwayREACTOME_REPRODUCTION

H3C1 H3-3A H3-4 H3C15

5.42e-04158344M26956
PathwayREACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION

H3C1 H3-3A H3C15

5.53e-0467343M27342
PathwayREACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION

H3C1 H3-3A H3C15

5.77e-0468343M27658
PathwayKEGG_MEDICUS_REFERENCE_TRANSCRIPTIONAL_ACTIVATION_BY_ACETYLATION_OF_H3K27

H3C1 H3-3A

5.81e-0415342M47973
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

H3C1 EHMT1 H3C15

6.28e-0470343M27231
PathwayREACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS

GTF2F1 H3C1 SREBF1 H3-3A H3C15

6.66e-04296345M27869
PathwayREACTOME_PRC2_METHYLATES_HISTONES_AND_DNA

H3C1 H3-3A H3C15

6.82e-0472343M27132
PathwayREACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION

H3C1 H3-3A H3C15

7.69e-0475343M27343
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

SREBF1 CHD9

8.43e-0418342M26942
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS

H3C1 H3-3A H3C15

1.26e-0389343M27943
PathwayREACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE

H3C1 H3-3A H3C15

1.30e-0390343M27691
PathwayREACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION

H3C1 H3-3A H3C15

1.30e-0390343M29668
PathwayREACTOME_RHO_GTPASES_ACTIVATE_PKNS

H3C1 H3-3A H3C15

1.43e-0393343M27487
PathwayREACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

H3C1 H3-3A H3C15

1.57e-0396343M27792
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_PIWI_INTERACTING_RNAS_PIRNAS

H3C1 H3-3A H3C15

1.62e-0397343M48262
PathwayREACTOME_ESR_MEDIATED_SIGNALING

GTF2F1 H3C1 H3-3A H3C15

1.85e-03220344M27794
PathwayREACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH

H3C1 H3-3A H3C15

1.98e-03104343M29829
PathwayREACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

H3C1 H3-3A H3C15

2.03e-03105343M27425
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

H3C1 H3-3A H3C15

2.09e-03106343M27458
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_KRAB_ZFP_PROTEINS

H3C1 H3-3A H3C15

2.14e-03107343M48260
PathwayREACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

H3C1 H3-3A H3C15

2.20e-03108343M27426
PathwayWP_NF1_COPY_NUMBER_VARIATION_SYNDROME

NF1 H3C1 H3C15

2.26e-03109343M48084
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

H3C1 H3-3A H3-4 H3C15

2.29e-03233344M27099
PathwayREACTOME_AMYLOID_FIBER_FORMATION

H3C1 H3-3A H3C15

2.32e-03110343M27958
PathwayREACTOME_RNA_POLYMERASE_I_TRANSCRIPTION

H3C1 H3-3A H3C15

2.32e-03110343M27696
PathwayREACTOME_OVARIAN_TUMOR_DOMAIN_PROTEASES

OTUD3 VCPIP1

2.68e-0332342MM15290
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

H3C1 H3-3A H3C15

2.90e-03119343M607
PathwayREACTOME_CELLULAR_RESPONSES_TO_STIMULI

H3C1 NOX5 EHMT1 CHD9 H3-3A H3-4 H3C15

3.13e-03828347M27827
PathwayREACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE

H3C1 H3-3A H3C15

3.33e-03125343M27186
PathwayREACTOME_INTERLEUKIN_7_SIGNALING

H3C1 H3C15

3.38e-0336342M542
PathwayREACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS

H3C1 H3-3A H3C15

3.64e-03129343M27795
PathwayREACTOME_OVARIAN_TUMOR_DOMAIN_PROTEASES

OTUD3 VCPIP1

3.96e-0339342M27579
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

H3C1 EHMT1 H3C15 KDM6A

3.99e-03272344M29619
PathwayKEGG_MEDICUS_REFERENCE_GENE_SILENCING_BY_METHYLATION_OF_H3K27_AND_UBIQUITINATION_OF_H2AK119

H3C1 H3-3A

4.16e-0340342M47917
PathwayREACTOME_GENE_SILENCING_BY_RNA

H3C1 H3-3A H3C15

4.49e-03139343M715
PathwayREACTOME_REPLACEMENT_OF_PROTAMINES_BY_NUCLEOSOMES_IN_THE_MALE_PRONUCLEUS

H1-8 H3-3A

4.58e-0342342M48029
PathwayREACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP

SREBF1 CHD9

4.58e-0342342M27172
Pubmed

A standardized nomenclature for mammalian histone genes.

H3Y2 H1-10 H3C1 H3-3A H3-4 H3-7 H3C15

4.07e-117458736180920
Pubmed

Ligand-dependent activation of the farnesoid X-receptor directs arginine methylation of histone H3 by CARM1.

H3C1 H3-3A H3-7 H3C15

2.28e-091158415471871
Pubmed

Human PAD4 regulates histone arginine methylation levels via demethylimination.

H3-3A H3-4 H3-7 H3C15

2.28e-091158415345777
Pubmed

Expression patterns and post-translational modifications associated with mammalian histone H3 variants.

H3C1 H3-3A H3-7 H3C15

6.88e-091458416267050
Pubmed

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.

H3C1 H3-3A H3-7 H3C15

4.08e-082158411242053
Pubmed

Modifications of human histone H3 variants during mitosis.

H3-3A H3-7 H3C15

4.39e-08558316185088
Pubmed

Human spleen histone H3. Isolation and amino acid sequence.

H3-3A H3-7 H3C15

4.39e-0855837309716
Pubmed

Organismal differences in post-translational modifications in histones H3 and H4.

H3-3A H3-7 H3C15

8.77e-08658317194708
Pubmed

Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation.

H3-3A H3-7 H3C15

8.77e-08658310464286
Pubmed

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks.

H3-3A H3-7 H3C15

8.77e-08658315525939
Pubmed

Novel mitosis-specific phosphorylation of histone H3 at Thr11 mediated by Dlk/ZIP kinase.

H3-3A H3-7 H3C15

8.77e-08658312560483
Pubmed

Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification.

H3-3A H3-7 H3C15

8.77e-08658317189264
Pubmed

Phosphorylation of Ser28 in histone H3 mediated by mixed lineage kinase-like mitogen-activated protein triple kinase alpha.

H3-3A H3-7 H3C15

1.53e-07758315684425
Pubmed

Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation.

H3-3A H3-7 H3C15

1.53e-07758311856369
Pubmed

PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-alpha target gene activation by regulating lysine demethylase 1 specificity.

H3C1 H3-3A H3-4

1.53e-07758320448663
Pubmed

The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment.

H3-3A H3-7 H3C15

1.53e-07758315681610
Pubmed

Coactivator-associated arginine methyltransferase-1 enhances nuclear factor-kappaB-mediated gene transcription through methylation of histone H3 at arginine 17.

H3-3A H3-7 H3C15

1.53e-07758316497732
Pubmed

The human and mouse replication-dependent histone genes.

H1-8 H3C1 H3-4 H3-7 H3C15

1.95e-077758512408966
Pubmed

Human tNASP promotes in vitro nucleosome assembly with histone H3.3.

H3C1 H3-3A H3-4 H3C15

2.12e-073158425615412
Pubmed

Crystal structure of DPF3b in complex with an acetylated histone peptide.

H3C1 H3-3A H3-4

3.67e-07958327402533
Pubmed

Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TNRC18 FBF1 EHMT1 IRF2BPL VCPIP1

1.01e-0610758511347906
Pubmed

Serine ADP-Ribosylation Depends on HPF1.

H3C1 H3-3A H3-4

1.97e-061558328190768
Pubmed

Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.

RAP1GAP MACF1 OTUD3 IGSF3

2.40e-06565849455484
Pubmed

Human Asf1 regulates the flow of S phase histones during replicational stress.

H3C1 H3-3A H3-4

2.43e-061658315664198
Pubmed

DOC-2/DAB2 is the binding partner of myosin VI.

MYO6 DAB2

2.73e-06258211906161
Pubmed

Dynamic multimerization of Dab2-Myosin VI complexes regulates cargo processivity while minimizing cortical actin reorganization.

MYO6 DAB2

2.73e-06258233372034
Pubmed

Myosin VI targeting to clathrin-coated structures and dimerization is mediated by binding to Disabled-2 and PtdIns(4,5)P2.

MYO6 DAB2

2.73e-06258217187061
Pubmed

Grade Assignment by Ki-67 Proliferative Index, Mitotic Count, and Phosphohistone H3 Count in Surgically Resected Gastrointestinal and Pancreatic Neuroendocrine Tumors.

H3C1 MKI67

2.73e-06258229040195
Pubmed

A unique H3K4me2 profile marks tissue-specific gene regulation.

H3-3A H3-4

2.73e-06258220841431
Pubmed

Involvement of histone methyltransferase GLP in HIV-1 latency through catalysis of H3K9 dimethylation.

EHMT1 H3-4

2.73e-06258223541084
Pubmed

A dynamic Dab2 keeps myosin VI stably on track.

MYO6 DAB2

2.73e-06258234237899
Pubmed

Phosphohistone H3 and Ki-67 labeling indices in cytologic specimens from well-differentiated neuroendocrine tumors of the gastrointestinal tract and pancreas: a comparative analysis using automated image cytometry.

MKI67 H3-4

2.73e-06258224021213
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

H1-10 H3C1 MYO6 MKI67 DAB2 SEC61B CENPV H3-4 H3-7 H3C15

3.48e-06949581036574265
Pubmed

Regulation of transcription by the heterogeneous nuclear ribonucleoprotein E1B-AP5 is mediated by complex formation with the novel bromodomain-containing protein BRD7.

H3C1 H3-4 H3C15

3.53e-061858312489984
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

GTF2F1 H3C1 MKI67 CENPV H3C15 VCPIP1

3.85e-0625058633536335
Pubmed

Np95 is a histone-binding protein endowed with ubiquitin ligase activity.

H3C1 H3-3A H3-4

4.92e-062058314993289
Pubmed

The Polycomb Repressive Complex 1 Protein BMI1 Is Required for Constitutive Heterochromatin Formation and Silencing in Mammalian Somatic Cells.

H1-10 H3C1 CENPV

5.73e-062158326468281
Pubmed

Cargo binding induces dimerization of myosin VI.

MYO6 DAB2

8.19e-06358219805065
Pubmed

Competition between two high- and low-affinity protein-binding sites in myosin VI controls its cellular function.

MYO6 DAB2

8.19e-06358231744880
Pubmed

Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton.

MYO6 DAB2

8.19e-06358211967127
Pubmed

Molecular recognition of histone H3 by the WD40 protein WDR5.

H3C1 H3C15

8.19e-06358216829960
Pubmed

Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.

H3C1 H3C15

8.19e-06358216829959
Pubmed

Myosin VI regulates endocytosis of the cystic fibrosis transmembrane conductance regulator.

MYO6 DAB2

8.19e-06358215247260
Pubmed

Structures of human nucleosomes containing major histone H3 variants.

H3C1 H3-3A H3C15

1.56e-052958321636898
Pubmed

Viral reprogramming of the Daxx histone H3.3 chaperone during early Epstein-Barr virus infection.

H3C1 H3-3A

1.64e-05458225275136
Pubmed

Identification and characterization of propionylation at histone H3 lysine 23 in mammalian cells.

H3C1 H3C15

1.64e-05458219801601
Pubmed

The prognostic value of mitotic activity index (MAI), phosphohistone H3 (PPH3), cyclin B1, cyclin A, and Ki67, alone and in combinations, in node-negative premenopausal breast cancer.

MKI67 H3-4

1.64e-05458224324728
Pubmed

Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1.

H3C1 H3-4

1.64e-05458227595565
Pubmed

Histone methyltransferase Suv39h1 represses MyoD-stimulated myogenic differentiation.

H3C1 H3-4

1.64e-05458216858404
Pubmed

BREK/LMTK2 is a myosin VI-binding protein involved in endosomal membrane trafficking.

MYO6 DAB2

1.64e-05458218429820
Pubmed

UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development.

H3C1 KDM6A

1.64e-05458217713478
Pubmed

Human SFMBT is a transcriptional repressor protein that selectively binds the N-terminal tail of histone H3.

H3C1 H3-4

1.64e-05458217599839
Pubmed

JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin.

H3C1 H3-4

1.64e-05458219783980
Pubmed

G9a and Glp methylate lysine 373 in the tumor suppressor p53.

H3C1 EHMT1

1.64e-05458220118233
Pubmed

Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3.

H3C1 H3-4

1.64e-05458210436156
Pubmed

Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase.

H3C1 H3-4

1.64e-05458211779497
Pubmed

Transcription through the nucleosome.

H3C1 H3-4 H3C15

2.32e-053358331790919
Pubmed

DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network.

H3C1 H3-3A H3C15

2.32e-053358333857403
Pubmed

SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins.

H3-4 H3C15

2.72e-05558211959841
Pubmed

TSPYL2 Regulates the Expression of EZH2 Target Genes in Neurons.

H3C1 KDM6A

2.72e-05558230051352
Pubmed

Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis.

MYO6 DAB2

2.72e-05558215837803
Pubmed

ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation.

H3C1 H3C15

2.72e-05558217967883
Pubmed

HIV-1 Tat interactions with p300 and PCAF transcriptional coactivators inhibit histone acetylation and neurotrophin signaling through CREB.

H3C1 H3-4

2.72e-05558215611041
Pubmed

Human histone acetyltransferase 1 protein preferentially acetylates H4 histone molecules in H3.1-H4 over H3.3-H4.

H3C1 H3-4

2.72e-05558222228774
Pubmed

Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain.

H3C1 H3-3A

2.72e-05558219834512
Pubmed

Identification of the BRD1 interaction network and its impact on mental disorder risk.

H3C1 H3-3A H3-4

2.77e-053558327142060
Pubmed

A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks.

H3C1 H3-3A H3C15

3.02e-053658326167883
Pubmed

Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis.

H3C1 H3-3A H3-4

3.56e-053858314718166
Pubmed

Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension.

MYO6 DAB2

4.08e-05658231672988
Pubmed

Overexpression of myosin VI in prostate cancer cells enhances PSA and VEGF secretion, but has no effect on endocytosis.

MYO6 DAB2

4.08e-05658219855435
Pubmed

SAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradation.

NF1 MKI67

4.08e-05658222118770
Pubmed

Crosstalk between CARM1 methylation and CBP acetylation on histone H3.

H3C1 H3-3A

4.08e-05658212498683
Pubmed

The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing.

H3-3A KDM6A

4.08e-05658217825402
Pubmed

Structural biology of human H3K9 methyltransferases.

H3C1 EHMT1

4.08e-05658220084102
Pubmed

Histone deimination antagonizes arginine methylation.

H3-3A H3C15

4.08e-05658215339660
Pubmed

Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.

H3C1 H3-4

4.08e-05658224235145
Pubmed

Myo6 facilitates the translocation of endocytic vesicles from cell peripheries.

MYO6 DAB2

4.08e-05658212857860
Pubmed

Cloning and characterization of a novel human histone deacetylase, HDAC8.

H3C1 H3-4

4.08e-05658210926844
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

H1-10 NF1 MKI67 WRNIP1 DAB2 IRF2BPL KDM6A VCPIP1

4.17e-0577458815302935
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

GTF2F1 H3C1 MKI67 WRNIP1 EHMT1 CHD9 H3-3A IRF2BPL KDM6A

4.34e-05101458932416067
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CCDC13 RAP1GAP MYO6 APC2 MAST1 MACF1 CHD9 H3-3A KDM6A VCPIP1

4.75e-051285581035914814
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

H1-10 H3C1 C19orf53 SREBF1 MKI67 EHMT1 SEC61B CENPV KDM6A VCPIP1

5.04e-051294581030804502
Pubmed

Alpha-AP-2 directs myosin VI-dependent endocytosis of cystic fibrosis transmembrane conductance regulator chloride channels in the intestine.

MYO6 DAB2

5.71e-05758220351096
Pubmed

HIRA and Daxx constitute two independent histone H3.3-containing predeposition complexes.

H3C1 H3-3A

5.71e-05758221047901
Pubmed

Cytosolic GDH1 degradation restricts protein synthesis to sustain tumor cell survival following amino acid deprivation.

H3C1 KDM6A

5.71e-05758234269483
Pubmed

The pioneer factor activity of c-Myb involves recruitment of p300 and induction of histone acetylation followed by acetylation-induced chromatin dissociation.

H3C1 H3-4

5.71e-05758229954426
Pubmed

Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes.

H3C1 H3-3A

5.71e-05758215485929
Pubmed

MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output.

EHMT1 H3-4

5.71e-05758220588255
Pubmed

Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells.

MKI67 KDM6A

5.71e-05758224572572
Pubmed

MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14.

H3-3A H3-4

7.60e-05858212773393
Pubmed

Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation.

H3C1 H3-4

7.60e-05858211850410
Pubmed

H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis.

H3C1 H3-3A

7.60e-05858228300060
Pubmed

CtBP represses p300-mediated transcriptional activation by direct association with its bromodomain.

H3C1 H3-3A

7.60e-05858215834423
Pubmed

Septin7 regulates inner ear formation at an early developmental stage.

MYO6 MKI67

7.60e-05858227634570
Pubmed

UTX deficiency in neural stem/progenitor cells results in impaired neural development, fetal ventriculomegaly, and postnatal death.

MKI67 KDM6A

7.60e-05858236412518
Pubmed

A Cul4 E3 ubiquitin ligase regulates histone hand-off during nucleosome assembly.

H3-3A H3-4

7.60e-05858224209620
Pubmed

RPA Interacts with HIRA and Regulates H3.3 Deposition at Gene Regulatory Elements in Mammalian Cells.

H3C1 H3-3A

7.60e-05858228107649
Pubmed

H3K27me3 demethylase UTX regulates the differentiation of a subset of bipolar cells in the mouse retina.

MKI67 KDM6A

7.60e-05858232215989
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

GJA3 H3C1 MKI67 MACF1 H3-3A H3-4 H3-7 H3C15

7.63e-0584458825963833
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

GTF2F1 TNRC18 C19orf53 MKI67 WRNIP1 EHMT1 CHD9 H3-3A KDM6A

8.28e-05110358934189442
InteractionH2BC5 interactions

H1-8 TNRC18 H3C1 FBF1 MKI67 H3-3A H3-4 H3-7 H3C15 IGSF3

2.72e-083315710int:H2BC5
InteractionH2BC9 interactions

H1-10 H1-8 TNRC18 H3C1 MYO6 FBF1 H3-3A H3-4 H3-7 H3C15 KIAA1614

4.07e-084465711int:H2BC9
InteractionH2AC14 interactions

H1-10 H3C1 MKI67 H3-3A H3-4 H3-7 H3C15

1.61e-07144577int:H2AC14
InteractionH2AC11 interactions

H1-10 H1-8 TNRC18 H3C1 FAM217B H3-3A H3-4 H3C15

4.61e-07248578int:H2AC11
InteractionKIF20B interactions

H3C1 TOPAZ1 ASTE1 MKI67 H3-3A VCPIP1

5.66e-07107576int:KIF20B
InteractionH2AC12 interactions

H1-10 H3C1 H3-3A H3-4 H3-7 H3C15

1.01e-06118576int:H2AC12
InteractionH2BC13 interactions

TNRC18 H3C1 MKI67 H3-3A H3-4 H3-7 H3C15

2.05e-06210577int:H2BC13
InteractionKDM5A interactions

H3C1 H3-3A H3-4 H3C15 KDM6A

2.10e-0674575int:KDM5A
InteractionMPHOSPH8 interactions

ATG16L1 H3C1 SREBF1 EHMT1 H3-3A

6.50e-0693575int:MPHOSPH8
InteractionH3C1 interactions

H1-10 GTF2F1 TNRC18 H3C1 MYO6 MKI67 EHMT1 H3-3A H3-4 H3-7 H3C15 KDM6A

6.53e-069015712int:H3C1
InteractionFMNL3 interactions

MYO6 MKI67 FHDC1 H3-7

1.11e-0549574int:FMNL3
InteractionCBX3 interactions

ATG16L1 H3C1 MKI67 WRNIP1 EHMT1 MACF1 CHD9 H3-3A H3-4 H3C15

1.18e-056465710int:CBX3
InteractionH4C9 interactions

H3C1 EHMT1 H3-3A H3-4 H3-7

1.35e-05108575int:H4C9
InteractionH1-3 interactions

H1-10 TNRC18 H3C1 H3-3A H3-4 H3-7 H3C15

1.74e-05291577int:H1-3
InteractionHMGA1 interactions

H1-10 ATG16L1 TNRC18 H3C1 H3-3A H3-4 H3-7 H3C15

2.21e-05419578int:HMGA1
InteractionNASP interactions

H3C1 MACF1 H3-3A H3-4 H3-7 H3C15

2.56e-05207576int:NASP
InteractionH3-4 interactions

H1-10 H3C1 EHMT1 H3-3A FHDC1 H3-4 H3C15 KDM6A

3.56e-05448578int:H3-4
InteractionLOC102724334 interactions

H3C1 H3-3A H3-4 H3-7 H3C15

3.83e-05134575int:LOC102724334
InteractionH2AC21 interactions

H1-10 ATG16L1 H3C1 H3-4 H3-7 H3C15

5.09e-05234576int:H2AC21
InteractionSUV39H1 interactions

H3C1 EHMT1 H3-3A H3-4 H3-7 H3C15

5.59e-05238576int:SUV39H1
InteractionDAXX interactions

TNRC18 H3C1 MKI67 MACF1 CHD9 H3-3A H3-4

5.94e-05353577int:DAXX
InteractionBNIP2 interactions

ATG16L1 MYO6 SEC61B GSC2

6.02e-0575574int:BNIP2
InteractionH2AC13 interactions

H3C1 H3-3A H3-4 H3C15

6.02e-0575574int:H2AC13
InteractionCHAMP1 interactions

H3C1 MKI67 EHMT1 H3-3A H3-4

6.15e-05148575int:CHAMP1
InteractionH2AC18 interactions

TNRC18 H3C1 H3-3A H3-4 H3C15

6.15e-05148575int:H2AC18
InteractionCBX5 interactions

ATG16L1 H3C1 MKI67 EHMT1 H3-3A H3-4 H3C15

6.26e-05356577int:CBX5
InteractionTAF6 interactions

ATG16L1 GTF2F1 H3C1 MYO6 MKI67 H3-4

6.56e-05245576int:TAF6
InteractionHDAC9 interactions

H1-10 MKI67 H3-3A H3C15

7.02e-0578574int:HDAC9
InteractionSETD7 interactions

ATG16L1 H3C1 H3-3A H3-4

7.02e-0578574int:SETD7
InteractionSUZ12 interactions

H1-10 CCDC9B NF1 H3C1 SREBF1 MKI67 H3-3A H3-4 KDM6A

7.50e-05644579int:SUZ12
InteractionH1-0 interactions

H1-10 H3C1 MKI67 H3-3A H3-4 H3C15

8.36e-05256576int:H1-0
InteractionH2AC4 interactions

H1-10 H3C1 CENPV CHD9 H3-3A H3-4 H3-7 H3C15

8.38e-05506578int:H2AC4
InteractionSLFN11 interactions

GTF2F1 H3C1 SREBF1 MKI67 CENPV H3C15 VCPIP1

8.82e-05376577int:SLFN11
InteractionH2BC4 interactions

H1-10 TNRC18 H3C1 H3-3A H3-4 H3C15

8.91e-05259576int:H2BC4
InteractionTAF1 interactions

GTF2F1 H3C1 FBF1 WRNIP1 H3-3A H3-4

9.10e-05260576int:TAF1
InteractionH2AC25 interactions

H3C1 H3-3A H3-4 H3C15

9.38e-0584574int:H2AC25
InteractionH1-2 interactions

H1-10 H1-8 GTF2F1 H3C1 H3-3A H3-4 H3-7 H3C15 IGSF3

9.70e-05666579int:H1-2
InteractionPARP10 interactions

ATG16L1 H3C1 H3-3A

1.10e-0433573int:PARP10
InteractionZMYM4 interactions

H3C1 TOPAZ1 MKI67 H3-3A H3-4

1.22e-04171575int:ZMYM4
InteractionMYO6 interactions

H3C1 MYO6 APC2 WRNIP1 DAB2 H3C15 FBXO34

1.26e-04398577int:MYO6
InteractionPRMT2 interactions

GJA3 GTF2F1 MYO6 VCPIP1

1.28e-0491574int:PRMT2
InteractionH2BC21 interactions

H1-10 H3C1 MKI67 EHMT1 H3-3A H3-4 H3-7 H3C15 IGSF3

1.35e-04696579int:H2BC21
InteractionCBX1 interactions

H3C1 MKI67 EHMT1 H3-3A H3-4 H3C15

1.59e-04288576int:CBX1
InteractionPABPN1L interactions

H3C1 H3-4 H3C15

1.69e-0438573int:PABPN1L
InteractionMCM5 interactions

ATG16L1 H3C1 MKI67 H3-3A H3-4 H3-7 H3C15

1.75e-04420577int:MCM5
InteractionH2BC11 interactions

H1-10 H3C1 H3-3A H3-4 H3C15

1.80e-04186575int:H2BC11
InteractionH2AC6 interactions

H3C1 H3-3A H3-4 H3C15

1.84e-04100574int:H2AC6
InteractionKDM2A interactions

H1-10 H3C1 H3-3A H3-4

2.06e-04103574int:KDM2A
InteractionGTF3C4 interactions

H3C1 MAST1 H3-3A H3-4 H3C15

2.24e-04195575int:GTF3C4
InteractionHPF1 interactions

H3C1 H3-3A H3-4

2.28e-0442573int:HPF1
InteractionH2AC7 interactions

H3C1 H3-3A H3-4 H3C15

2.39e-04107574int:H2AC7
InteractionRALBP1 interactions

CCDC13 ATG16L1 H3C1 H3-3A H3-4

2.41e-04198575int:RALBP1
InteractionMOGS interactions

ATG16L1 NF1 H3C1 MKI67 SEC61B

2.41e-04198575int:MOGS
InteractionPRDM2 interactions

H3C1 H3-3A H3-4

2.44e-0443573int:PRDM2
InteractionH2AX interactions

ATG16L1 TNRC18 H3C1 MKI67 H3-3A H3-4 H3-7 H3C15

2.49e-04593578int:H2AX
InteractionKMT2A interactions

H3C1 MKI67 H3-3A H3-4 H3C15 KDM6A

2.54e-04314576int:KMT2A
InteractionEHMT2 interactions

H3C1 EHMT1 H3-3A IRF2BPL H3-4 H3C15

2.58e-04315576int:EHMT2
InteractionH2BC12 interactions

H1-10 TNRC18 H3C1 H3-3A H3-4 H3C15

2.90e-04322576int:H2BC12
InteractionH3C15 interactions

H3C1 MYO6 H3-3A H3-4 H3C15

2.96e-04207575int:H3C15
InteractionCBX7 interactions

H3C1 H3-3A H3-4

2.99e-0446573int:CBX7
InteractionUHRF1 interactions

H3C1 MKI67 H3-3A H3-4 H3C15

3.02e-04208575int:UHRF1
InteractionH3-5 interactions

H3C1 H3-3A H3-4 H3C15

3.04e-04114574int:H3-5
InteractionNFIC interactions

H3C1 MKI67 EHMT1 H3-3A KDM6A

3.16e-04210575int:NFIC
InteractionH1-5 interactions

H1-10 ATG16L1 H3C1 H3-3A H3-4 H3-7 H3C15

3.17e-04463577int:H1-5
InteractionNUMA1 interactions

H1-10 H3C1 MKI67 EHMT1 MACF1 H3-3A H3C15

3.42e-04469577int:NUMA1
InteractionLRWD1 interactions

H3C1 EHMT1 H3-3A H3-4

3.47e-04118574int:LRWD1
InteractionPRMT5 interactions

ATG16L1 GTF2F1 H3C1 SREBF1 MAST1 H3-3A H3-4

3.51e-04471577int:PRMT5
InteractionBLTP1 interactions

H3C1 SEC61B CHD9

3.60e-0449573int:BLTP1
InteractionNR3C1 interactions

ATG16L1 NF1 H3C1 MYO6 FBF1 EHMT1 CENPV CHD9 KDM6A IGSF3

3.62e-049745710int:NR3C1
InteractionC7orf50 interactions

H3C1 MKI67 MAST1 SEC61B H3-3A

3.75e-04218575int:C7orf50
InteractionHMGN2 interactions

ATG16L1 H3C1 H3-4 H3-7 H3C15

4.07e-04222575int:HMGN2
InteractionH2AJ interactions

H3C1 H3-3A H3-4 H3C15

4.59e-04127574int:H2AJ
InteractionH1-6 interactions

H1-8 H3C1 H3-3A H3-4 H3C15

4.69e-04229575int:H1-6
InteractionBMI1 interactions

H1-10 CCDC9B H3C1 MKI67 EHMT1 CENPV H3-4 KDM6A

5.03e-04659578int:BMI1
InteractionTNIP1 interactions

H1-10 H3C1 MYO6 FBF1 MKI67 DAB2 SEC61B CENPV H3-4 H3-7 H3C15

5.26e-0412175711int:TNIP1
InteractionKMT2C interactions

H3C1 H3-3A H3-4 KDM6A

5.62e-04134574int:KMT2C
InteractionKAT6A interactions

H1-10 GTF2F1 H3C1 C19orf53 H3-3A OTUD3 H3-4

5.65e-04510577int:KAT6A
InteractionIRF8 interactions

MYO6 EHMT1 KDM6A

5.93e-0458573int:IRF8
InteractionKDM1B interactions

H3C1 H3-3A H3-4

5.93e-0458573int:KDM1B
InteractionASCL2 interactions

H3C1 H3-3A

6.01e-0413572int:ASCL2
InteractionZFP91 interactions

H3C1 MKI67 MAST1 H3-3A

6.28e-04138574int:ZFP91
InteractionAP2B1 interactions

ATG16L1 H3C1 MYO6 MKI67 DAB2 VCPIP1

6.32e-04373576int:AP2B1
InteractionKDM5C interactions

H3-3A H3C15 KDM6A VCPIP1

6.45e-04139574int:KDM5C
InteractionRNF2 interactions

H1-10 CCDC9B H3C1 MKI67 EHMT1 CENPV H3-3A H3-4 KDM6A

6.75e-04866579int:RNF2
InteractionASF1A interactions

ATG16L1 GTF2F1 H3C1 H3-3A H3-4

6.86e-04249575int:ASF1A
InteractionCBX8 interactions

H1-10 H3C1 HAP1 H3-3A H3-4

6.86e-04249575int:CBX8
InteractionATAD2 interactions

H3C1 H3-3A H3-4

6.87e-0461573int:ATAD2
InteractionGTF2F2 interactions

ATG16L1 GTF2F1 H3C1 H3-3A

7.17e-04143574int:GTF2F2
InteractionMAD2L1 interactions

GTF2F1 H3C1 EHMT1 MACF1 CHD9

7.24e-04252575int:MAD2L1
InteractionDNTTIP2 interactions

H3C1 MKI67 H3-3A H3C15

7.36e-04144574int:DNTTIP2
InteractionTBP interactions

LRRC46 GTF2F1 H3C1 HAP1 H3-4

7.37e-04253575int:TBP
InteractionDNMT1 interactions

ATG16L1 H3C1 EHMT1 H3-3A H3-4

7.50e-04254575int:DNMT1
InteractionPOLR2A interactions

ATG16L1 GTF2F1 NF1 H3C1 MYO6 HAP1 SREBF1

7.57e-04536577int:POLR2A
InteractionRPS27A interactions

H1-8 TNRC18 H3C1 MYO6 H3-3A H3-4 H3C15

7.57e-04536577int:RPS27A
InteractionKIF18B interactions

H3C1 MKI67 H3-3A

7.91e-0464573int:KIF18B
InteractionZNF638 interactions

ATG16L1 NF1 H3C1 MYO6 SREBF1

8.48e-04261575int:ZNF638
InteractionNPM3 interactions

ATG16L1 MKI67 CENPV IRF2BPL H3C15

8.62e-04262575int:NPM3
InteractionCOIL interactions

ATG16L1 GTF2F1 MKI67 WRNIP1 FAM217B EHMT1 CHD9

8.99e-04552577int:COIL
InteractionING2 interactions

TNRC18 H3-3A H3-4

9.44e-0468573int:ING2
InteractionHMGN5 interactions

H1-10 H3C1 H3-3A H3C15

9.46e-04154574int:HMGN5
Cytoband3q22.1

H1-8 ASTE1

1.31e-03425823q22.1
GeneFamilyHistones

H1-10 H1-8 H3C1 H3-3A H3-4 H3-7 H3C15

1.74e-09116347864
GeneFamilyOTU domain containing

OTUD3 VCPIP1

4.59e-0417342669
GeneFamilyAAA ATPases

FIGNL2 WRNIP1

4.45e-0353342413
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAP1GAP CCDC9B NF1 HAP1 ASTE1 IRGQ

1.16e-071775868abdf1d970b2f15e17e185f3e612dd5065c88757
DrugFamprofazone [22881-35-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A

ATG16L1 NF1 EHMT1 C10orf95 KDM6A VCPIP1

9.22e-061955763834_DN
DrugNSC-629231

H1-8 H3C1 H3-3A H3-7

1.09e-0555574CID000363885
DiseaseGLIOMA SUSCEPTIBILITY 1

H3C1 H3-3A

4.37e-056512C2750850
Diseasealkaline phosphatase measurement

RASIP1 ATG16L1 ADAMTSL1 RAP1GAP NF1 MACF1 OTUD3 KIAA1614

3.27e-041015518EFO_0004533
Diseaseulcerative colitis, Crohn's disease

ATG16L1 OTUD3

5.46e-0420512EFO_0000384, EFO_0000729
Diseasekidney disease (biomarker_via_orthology)

SREBF1 MKI67

6.02e-0421512DOID:557 (biomarker_via_orthology)
DiseaseDrugs used in diabetes use measurement

ATG16L1 CCDC9B NF1 MACF1

9.90e-04255514EFO_0009924
DiseaseColorectal Carcinoma

CCDC9B NF1 APC2 MKI67 KDM6A PIK3R5

1.29e-03702516C0009402
DiseaseInflammatory Bowel Diseases

ATG16L1 APC2

1.68e-0335512C0021390

Protein segments in the cluster

PeptideGeneStartEntry
SRAATKRLSQPAGGL

ATG16L1

261

Q676U5
LATKAARKRASPTGG

H3Y2

21

P0DPK5
ASLGKASSRKPFGIL

FBXO34

51

Q9NWN3
LSKARLPLGATSSKG

ASTE1

236

Q2TB18
KAAGGASGSRAKRIS

RASIP1

76

Q5U651
SFKASDPLGRGSKRL

NOX5

521

Q96PH1
STKPGRGRRTAKSSA

DAB2

436

P98082
KPGSARRSQGAVAKS

FHDC1

876

Q9C0D6
RAPSSAGGLSRKAKA

H1-8

226

Q8IZA3
AGGLSRKAKAKGSRS

H1-8

231

Q8IZA3
LATKAARKSAPSTGG

H3-3A

21

P84243
AAGSRRADKKPARGQ

H1-10

151

Q92522
TSSDNSGRRRKGPFK

KDM6A

1066

O15550
SALGQSSRPKLGKSR

KIAA1614

1011

Q5VZ46
SKTAAAASEKNRGPR

C19orf53

16

Q9UNZ5
SKAEKRGLAANPGSR

ADAMTSL1

1006

Q8N6G6
APATGSKARGKERLT

CCDC9B

321

Q6ZUT6
LATKAARKSAPATGG

H3-7

21

Q5TEC6
APSGRGAAASLRKRK

IRF2BPL

531

Q9H1B7
GALKSPGRSKLIASA

FAM217B

216

Q9NTX9
APFIEKSRSGGRKSL

MACF1

3081

O94854
LATKVARKSAPATGG

H3-4

21

Q16695
GRKGARAATAPKASV

LRRC46

291

Q96FV0
GAAGLEPRKLSSKTR

FGD3

516

Q5JSP0
LLVSRKSRPKSGGSG

MKI67

286

P46013
LATKAARKSAPATGG

H3C1

21

P68431
RPSRTGGKVIKSASA

MAST1

901

Q9Y2H9
KKSASRPGSRAGSRA

MACF1

7306

Q9UPN3
AAKSRPGSGSRKAEA

OTUD3

6

Q5T2D3
GSARRPEKRGAASVK

APC2

1746

O95996
GRRPKSGIAKATAAA

CHD9

2631

Q3L8U1
AGSPAKASQASKLRA

FBF1

401

Q8TES7
YSLRTKAGGKRSSPG

IGSF3

991

O75054
RASASARLLPGVKKS

GSC2

186

O15499
GRLAKARGPRSSSAA

COL20A1

1011

Q9P218
ASEAGAKAGARRPSA

HAP1

71

P54257
KASASQRAAPRTKTG

CCDC13

611

Q8IYE1
KLRGQKRSGASGASA

CENPV

11

Q7Z7K6
GRGSAPSKNKRRAFL

CYP4V2

286

Q6ZWL3
APGAESGLSLKRKAA

FIGNL2

256

A6NMB9
LGDPGRASKASRASS

GJA3

411

Q9Y6H8
RRSRKKPSGALGSES

EHMT1

446

Q9H9B1
SPSAARTKAAALRAG

IRGQ

466

Q8WZA9
RAKIPGTGALASAAA

RTN2

521

O75298
KRERKPSGGSSRGNS

GTF2F1

371

P35269
GAGTTTAKKRRSSLG

RIMS3

36

Q9UJD0
LATKAARKSAPATGG

H3C15

21

Q71DI3
TRKKSGPFGSRRSSA

RAP1GAP

486

P47736
GSKAPASAQSRGEKR

SREBF1

311

P36956
SAGAPSKNSSRLGGR

C10orf95

31

Q9H7T3
AKGSSSRDGPAKERA

TNRC18

196

O15417
AKAETARRLAGPGST

ZFP92

376

A6NM28
AATRAIKASGPGSKR

PIK3R5

701

Q8WYR1
RSPSKAVAARAAGST

SEC61B

16

P60468
LRTPGASLRKGKGNS

NF1

651

P21359
SLASAAASGGLLKRR

VCPIP1

26

Q96JH7
LAGPSRKGSFKIRLS

SOCS7

201

O14512
DKSVAASGAGKAARR

TOPAZ1

66

Q8N9V7
RKGSGKRPAAAAAAG

WRNIP1

136

Q96S55
LSRGPAVLATKAAAG

MYO6

1066

Q9UM54