Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	type I interferon receptor binding	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.67e-09	17	159	6	GO:0005132
GeneOntologyMolecularFunction	cysteine-type peptidase activity	USP17L7 USP34 CAPN3 BRCC3 GGH MINDY4 SENP7 CAPN15 USP17L13	2.40e-05	192	159	9	GO:0008234
GeneOntologyMolecularFunction	high-affinity IgG receptor activity	FCGR1A FCGR1BP	6.30e-05	2	159	2	GO:0019771
GeneOntologyMolecularFunction	leukotriene receptor binding	FCGR1A FCGR1BP	6.30e-05	2	159	2	GO:0031774
GeneOntologyMolecularFunction	immunoglobulin receptor activity	FCER1A FCGR1A FCGR1BP	1.69e-04	14	159	3	GO:0019763
GeneOntologyBiologicalProcess	positive regulation of peptidyl-serine phosphorylation of STAT protein	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	9.41e-09	21	159	6	GO:0033141
GeneOntologyBiologicalProcess	regulation of peptidyl-serine phosphorylation of STAT protein	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.29e-08	24	159	6	GO:0033139
GeneOntologyBiologicalProcess	serine phosphorylation of STAT protein	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	6.25e-08	28	159	6	GO:0042501
GeneOntologyBiologicalProcess	natural killer cell activation involved in immune response	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	7.96e-07	42	159	6	GO:0002323
GeneOntologyBiologicalProcess	response to exogenous dsRNA	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	4.05e-06	55	159	6	GO:0043330
GeneOntologyBiologicalProcess	B cell proliferation	TLR9 IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21 BST1	5.40e-06	124	159	8	GO:0042100
GeneOntologyBiologicalProcess	response to dsRNA	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	9.02e-06	63	159	6	GO:0043331
GeneOntologyBiologicalProcess	phosphatidylinositol-mediated signaling	PIK3C2A PIK3C2G PI4KA PLCH2	3.20e-05	24	159	4	GO:0048015
GeneOntologyBiologicalProcess	leukocyte proliferation	ST6GAL1 TLR9 ACE IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 STAT6 IFNA21 BLM BST1 IL6ST	4.28e-05	445	159	13	GO:0070661
GeneOntologyBiologicalProcess	type I interferon-mediated signaling pathway	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	5.05e-05	85	159	6	GO:0060337
GeneOntologyBiologicalProcess	cellular response to type I interferon	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	5.40e-05	86	159	6	GO:0071357
GeneOntologyBiologicalProcess	cellular response to virus	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	6.97e-05	90	159	6	GO:0098586
GeneOntologyBiologicalProcess	mononuclear cell proliferation	ST6GAL1 TLR9 ACE IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21 BLM BST1 IL6ST	7.60e-05	406	159	12	GO:0032943
GeneOntologyBiologicalProcess	response to type I interferon	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	7.88e-05	92	159	6	GO:0034340
GeneOntologyBiologicalProcess	regulation of defense response to virus by host	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	1.25e-04	63	159	5	GO:0050691
GeneOntologyBiologicalProcess	positive regulation of peptidyl-serine phosphorylation	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.32e-04	101	159	6	GO:0033138
GeneOntologyBiologicalProcess	T cell activation involved in immune response	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 STAT6 IFNA21	1.53e-04	148	159	7	GO:0002286
GeneOntologyBiologicalProcess	cell surface receptor signaling pathway via JAK-STAT	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 STAT6 IFNA21 IL6ST	1.54e-04	198	159	8	GO:0007259
GeneOntologyBiologicalProcess	positive regulation of hypersensitivity	FCER1A FCGR1A FCGR1BP	1.91e-04	15	159	3	GO:0002885
GeneOntologyBiologicalProcess	peptidyl-amino acid modification	RELN ERO1A CAPN3 LRRK1 ITGA5 ACE IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21 FCER1A BST1 LRP4 ARHGEF2 IL6ST SENP7 RNF212B	1.92e-04	976	159	19	GO:0018193
GeneOntologyBiologicalProcess	interferon-mediated signaling pathway	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.33e-04	112	159	6	GO:0140888
GeneOntologyBiologicalProcess	antigen processing and presentation of peptide antigen via MHC class I	MFSD6 ACE FCGR1A FCGR1BP	2.76e-04	41	159	4	GO:0002474
GeneOntologyBiologicalProcess	cell surface receptor signaling pathway via STAT	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 STAT6 IFNA21 IL6ST	2.78e-04	216	159	8	GO:0097696
GeneOntologyBiologicalProcess	positive regulation of acute inflammatory response to antigenic stimulus	FCER1A FCGR1A FCGR1BP	2.82e-04	17	159	3	GO:0002866
GeneOntologyBiologicalProcess	positive regulation of acute inflammatory response	FCER1A FCGR1A FCGR1BP IL6ST	3.03e-04	42	159	4	GO:0002675
GeneOntologyBiologicalProcess	antigen processing and presentation of exogenous peptide antigen via MHC class I	MFSD6 FCGR1A FCGR1BP	3.37e-04	18	159	3	GO:0042590
GeneOntologyBiologicalProcess	regulation of early endosome to recycling endosome transport	DNAJC13 SORL1	3.51e-04	4	159	2	GO:1902954
GeneOntologyBiologicalProcess	regulation of hypersensitivity	FCER1A FCGR1A FCGR1BP	3.98e-04	19	159	3	GO:0002883
GeneOntologyBiologicalProcess	natural killer cell activation	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	4.03e-04	124	159	6	GO:0030101
GeneOntologyBiologicalProcess	regulation of receptor signaling pathway via JAK-STAT	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	4.21e-04	125	159	6	GO:0046425
GeneOntologyBiologicalProcess	regulation of phosphorylation	RELN NRBF2 FN1 COX11 LRRK1 TLR9 ITGA5 IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21 MOB2 BLM CCNH FCER1A BST1 LRP4 ARHGEF2 IL6ST	4.90e-04	1226	159	21	GO:0042325
GeneOntologyBiologicalProcess	type III hypersensitivity	FCGR1A FCGR1BP	5.82e-04	5	159	2	GO:0001802
GeneOntologyBiologicalProcess	regulation of type III hypersensitivity	FCGR1A FCGR1BP	5.82e-04	5	159	2	GO:0001803
GeneOntologyBiologicalProcess	positive regulation of type III hypersensitivity	FCGR1A FCGR1BP	5.82e-04	5	159	2	GO:0001805
Domain	Interferon	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	3.02e-09	17	152	6	PF00143
Domain	INTERFERON_A_B_D	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	3.02e-09	17	152	6	PS00252
Domain	Interferon_alpha/beta/delta	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	3.02e-09	17	152	6	IPR000471
Domain	IFabd	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	3.02e-09	17	152	6	SM00076
Domain	-	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	3.11e-06	50	152	6	1.20.1250.10
Domain	4_helix_cytokine_core	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	3.50e-06	51	152	6	IPR012351
Domain	ARM-type_fold	USP34 DNAJC13 CLTCL1 MROH2A MEI1 TEX10 FOCAD PIK3C2A PIK3C2G PI4KA STKLD1 TARBP1	2.21e-05	339	152	12	IPR016024
Domain	4_helix_cytokine-like_core	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	3.09e-05	74	152	6	IPR009079
Domain	PI3Ka	PIK3C2A PIK3C2G PI4KA	4.28e-05	9	152	3	PF00613
Domain	PI3Ka	PIK3C2A PIK3C2G PI4KA	4.28e-05	9	152	3	SM00145
Domain	-	PIK3C2A PIK3C2G PI4KA	4.28e-05	9	152	3	1.25.40.70
Domain	PI_Kinase	PIK3C2A PIK3C2G PI4KA	6.08e-05	10	152	3	IPR015433
Domain	PInositide-3_kin_accessory_dom	PIK3C2A PIK3C2G PI4KA	6.08e-05	10	152	3	IPR001263
Domain	PIK_HELICAL	PIK3C2A PIK3C2G PI4KA	6.08e-05	10	152	3	PS51545
Domain	PI3/4_kinase_CS	PIK3C2A PIK3C2G PI4KA	2.24e-04	15	152	3	IPR018936
Domain	-	PIK3C2A PIK3C2G PI4KA	2.74e-04	16	152	3	1.10.1070.11
Domain	PI3Kc	PIK3C2A PIK3C2G PI4KA	2.74e-04	16	152	3	SM00146
Domain	PI3_PI4_kinase	PIK3C2A PIK3C2G PI4KA	3.94e-04	18	152	3	PF00454
Domain	PI3_4_KINASE_1	PIK3C2A PIK3C2G PI4KA	3.94e-04	18	152	3	PS00915
Domain	PI3_4_KINASE_2	PIK3C2A PIK3C2G PI4KA	3.94e-04	18	152	3	PS00916
Domain	PI3/4_kinase_cat_dom	PIK3C2A PIK3C2G PI4KA	3.94e-04	18	152	3	IPR000403
Domain	PI3_4_KINASE_3	PIK3C2A PIK3C2G PI4KA	3.94e-04	18	152	3	PS50290
Domain	PI3K_Ras-bd_dom	PIK3C2A PIK3C2G	1.35e-03	7	152	2	IPR000341
Domain	PI3K_rbd	PIK3C2A PIK3C2G	1.35e-03	7	152	2	SM00144
Domain	PI3K_rbd	PIK3C2A PIK3C2G	1.35e-03	7	152	2	PF00794
Domain	PI3K_RBD	PIK3C2A PIK3C2G	1.35e-03	7	152	2	PS51546
Pathway	KEGG_MEDICUS_REFERENCE_TLR7_9_IRF7_SIGNALING_PATHWAY	TLR9 IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.18e-10	20	112	7	M47617
Pathway	KEGG_MEDICUS_REFERENCE_TLR7_8_9_IRF5_SIGNALING_PATHWAY	TLR9 IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.56e-10	22	112	7	M47897
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_TAT_TO_TLR2_4_NFKB_SIGNALING_PATHWAY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.53e-09	17	112	6	M47564
Pathway	KEGG_MEDICUS_REFERENCE_IFN_RIPK1_3_SIGNALING_PATHWAY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 STAT6 IFNA21	3.72e-09	31	112	7	M47964
Pathway	KEGG_MEDICUS_REFERENCE_CGAS_STING_SIGNALING_PATHWAY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	3.77e-09	18	112	6	M47539
Pathway	KEGG_MEDICUS_REFERENCE_TLR3_IRF7_SIGNALING_PATHWAY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	5.48e-09	19	112	6	M47450
Pathway	REACTOME_EVASION_BY_RSV_OF_HOST_INTERFERON_RESPONSES	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21 CUL5	9.26e-09	35	112	7	M48246
Pathway	KEGG_MEDICUS_REFERENCE_TYPE_II_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.08e-08	21	112	6	M47909
Pathway	KEGG_MEDICUS_REFERENCE_RIG_I_NFKB_SIGNALING_PATHWAY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.48e-08	22	112	6	M47616
Pathway	KEGG_MEDICUS_REFERENCE_TYPE_I_IFN_SIGNALING_PATHWAY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.99e-08	23	112	6	M47452
Pathway	REACTOME_REGULATION_OF_IFNA_IFNB_SIGNALING	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.99e-08	23	112	6	MM15634
Pathway	KEGG_MEDICUS_REFERENCE_RIG_I_IRF7_3_SIGNALING_PATHWAY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.63e-08	24	112	6	M47576
Pathway	KEGG_MEDICUS_REFERENCE_MDA5_IRF7_3_SIGNALING_PATHWAY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.63e-08	24	112	6	M47782
Pathway	KEGG_MEDICUS_REFERENCE_TYPE_I_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.63e-08	24	112	6	M47908
Pathway	REACTOME_REGULATION_OF_IFNA_IFNB_SIGNALING	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	4.45e-08	26	112	6	M982
Pathway	REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.12e-07	30	112	6	M936
Pathway	WP_SARS_CORONAVIRUS_AND_INNATE_IMMUNITY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.38e-07	31	112	6	M39897
Pathway	REACTOME_INTERFERON_ALPHA_BETA_SIGNALING	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.47e-07	34	112	6	MM15631
Pathway	KEGG_REGULATION_OF_AUTOPHAGY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.96e-07	35	112	6	M6382
Pathway	BIOCARTA_IFNA_PATHWAY	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	3.08e-07	19	112	5	MM1571
Pathway	WP_INTERFERONMEDIATED_SIGNALING	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	4.18e-07	37	112	6	M39785
Pathway	BIOCARTA_CYTOKINE_PATHWAY	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	2.46e-06	28	112	5	MM1378
Pathway	KEGG_AUTOIMMUNE_THYROID_DISEASE	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	3.32e-06	52	112	6	M13103
Pathway	KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	4.64e-06	55	112	6	M11844
Pathway	BIOCARTA_INFLAM_PATHWAY	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	5.75e-06	33	112	5	MM1379
Pathway	PID_CD8_TCR_DOWNSTREAM_PATHWAY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.24e-05	65	112	6	M272
Pathway	REACTOME_RSV_HOST_INTERACTIONS	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21 CUL5	1.26e-05	98	112	7	M48247
Pathway	WP_CYTOKINES_AND_INFLAMMATORY_RESPONSE	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	1.34e-05	39	112	5	MM15914
Pathway	KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY	TLR9 IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.64e-05	102	112	7	M3261
Pathway	BIOCARTA_IL1R_PATHWAY	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	1.73e-05	41	112	5	MM1493
Pathway	WP_TOLLLIKE_RECEPTOR_SIGNALING	TLR9 IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.75e-05	103	112	7	M39434
Pathway	KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.07e-05	71	112	6	M15913
Pathway	WP_CYTOSOLIC_DNASENSING_PATHWAY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.43e-05	73	112	6	M39837
Pathway	KEGG_JAK_STAT_SIGNALING_PATHWAY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 STAT6 IFNA21 IL6ST	3.22e-05	155	112	8	M17411
Pathway	REACTOME_INTERFERON_ALPHA_BETA_SIGNALING	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	3.55e-05	78	112	6	M973
Pathway	REACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_PATHWAY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21 CUL5	4.70e-05	120	112	7	M48233
Pathway	REACTOME_DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	4.71e-05	82	112	6	M1002
Pathway	WP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY	RELN FN1 ITGA5 IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21 PIK3C2A PIK3C2G	5.60e-05	326	112	11	MM15917
Pathway	KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	7.02e-05	88	112	6	M16004
Pathway	WP_MEASLES_VIRUS_INFECTION	TLR9 IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.04e-04	136	112	7	M42547
Pathway	WP_HEPATITIS_B_INFECTION	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 STAT6 IFNA21	1.99e-04	151	112	7	M39801
Pathway	REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE	PIK3C2A PIK3C2G PI4KA	3.65e-04	18	112	3	M645
Pathway	REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE	PIK3C2A PIK3C2G PI4KA	3.65e-04	18	112	3	MM14642
Pathway	REACTOME_SARS_COV_2_ACTIVATES_MODULATES_INNATE_AND_ADAPTIVE_IMMUNE_RESPONSES	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	5.00e-04	126	112	6	M45009
Pathway	WP_OVERVIEW_OF_PROINFLAMMATORY_AND_PROFIBROTIC_MEDIATORS	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	5.21e-04	127	112	6	M42533
Pathway	WP_IL2_SIGNALING_PATHWAY	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	6.37e-04	87	112	5	MM15915
Pathway	KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	7.77e-04	137	112	6	M5669
Pathway	REACTOME_INTERFERON_SIGNALING	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	8.07e-04	138	112	6	MM15635
Pathway	REACTOME_FIBRONECTIN_MATRIX_FORMATION	FN1 ITGA5	9.19e-04	6	112	2	M26970
Pathway	KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21 CXCR6 IL6ST	1.21e-03	264	112	8	M9809
Pathway	REACTOME_INTERFERON_SIGNALING	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21 FCGR1A FCGR1BP	1.49e-03	273	112	8	M983
Pathway	WP_PI3KAKT_SIGNALING	RELN FN1 ITGA5 IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.51e-03	339	112	9	M39736
Pathway	REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.35e-03	170	112	6	M941
Pubmed	HIV-1 gp120 inhibits TLR9-mediated activation and IFN-{alpha} secretion in plasmacytoid dendritic cells.	TLR9 IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.01e-12	19	162	7	17360657
Pubmed	Type I interferon production by tertiary lymphoid tissue developing in response to 2,6,10,14-tetramethyl-pentadecane (pristane).	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	8.40e-12	12	162	6	16565497
Pubmed	Evolution of the interferon alpha gene family in eutherian mammals.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	8.40e-12	12	162	6	17512142
Pubmed	Repression of the murine interferon alpha 11 gene: identification of negatively acting sequences.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	8.40e-12	12	162	6	1886773
Pubmed	Multiple pathways of interferon-induced gene expression in murine macrophages.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	8.40e-12	12	162	6	7684767
Pubmed	Negative regulation of the alpha interferon-induced antiviral response by the Ras/Raf/MEK pathway.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	8.40e-12	12	162	6	16611902
Pubmed	Interferon-alpha subtype 11 activates NK cells and enables control of retroviral infection.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	8.40e-12	12	162	6	22912583
Pubmed	Structure and expression of a new murine interferon-alpha gene: MuIFN-alpha I9.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	8.40e-12	12	162	6	3758677
Pubmed	Mapping the genetic region coding for herpes simplex virus resistance to mouse interferon alpha/beta.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	8.40e-12	12	162	6	8245849
Pubmed	The virus-induced factor VIF differentially recognizes the virus-responsive modules of the mouse IFNA4 gene promoter.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	8.40e-12	12	162	6	11846978
Pubmed	Identification of distal silencing elements in the murine interferon-A11 gene promoter.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	8.40e-12	12	162	6	8760352
Pubmed	Role of interferons in the regulation of cell proliferation, differentiation, and development.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	8.40e-12	12	162	6	7530016
Pubmed	Nonviral interferon alpha gene therapy inhibits growth of established tumors by eliciting a systemic immune response.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	8.40e-12	12	162	6	9794206
Pubmed	Characterization of murine interferon-alpha 12 (MuIFN-alpha12): biological activities and gene expression.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	8.40e-12	12	162	6	17451966
Pubmed	Characterization of interferon-alpha 13, a novel constitutive murine interferon-alpha subtype.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	12930842
Pubmed	Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	2014240
Pubmed	An interferon-alpha-induced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	18005734
Pubmed	Differential effect of murine alpha/beta interferon transgenes on antagonization of herpes simplex virus type 1 replication.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	12050368
Pubmed	Isolation and bacterial expression of a murine alpha leukocyte interferon gene.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	6094686
Pubmed	Isolation and characterization of a novel interferon-alpha-encoding gene, IFN-alpha 11, within a murine IFN cluster.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	1655578
Pubmed	Isolation and characterization of a functional murine interferon alpha gene which is not expressed in fibroblasts upon virus induction.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	2471809
Pubmed	Interferon alpha-mediated inhibition of human immunodeficiency virus type 1 provirus synthesis in T-cells.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	8438572
Pubmed	Interferon-alpha and -gamma differentially reduce rapid immature T-cell death by contact with HIV-1 carrier cell clones in vitro.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	9343822
Pubmed	Evidence for a different susceptibility of primate lentiviruses to type I interferons.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	23255800
Pubmed	Distinction of mouse interferon-alpha subtypes by polymerase chain reaction utilizing consensus primers and type-specific oligonucleotide probes.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	7523540
Pubmed	Partial inhibition of human immunodeficiency virus replication by type I interferons: impact of cell-to-cell viral transfer.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	19706714
Pubmed	Organization, structure and expression of murine interferon alpha genes.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	2987810
Pubmed	Anti-retroviral effects of type I IFN subtypes in vivo.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	19130550
Pubmed	HIV-1 Gag-virus-like particles inhibit HIV-1 replication in dendritic cells and T cells through IFN-α-dependent upregulation of APOBEC3G and 3F.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	22739040
Pubmed	Obstruction of HIV-1 particle release by interferon-alpha occurs before viral protease processing and is independent of envelope glycoprotein.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	9181467
Pubmed	Sequencing and bacterial expression of a novel murine alpha interferon gene.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	18726328
Pubmed	Distinct signature type I interferon responses are determined by the infecting virus and the target cell.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	18572754
Pubmed	Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7.	TLR9 IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	1.55e-11	13	162	6	15723075
Pubmed	Interferon induction by HIV glycoprotein 120: role of the V3 loop.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	7526537
Pubmed	Exogenous HIV-1 Vpr disrupts IFN-alpha response by plasmacytoid dendritic cells (pDCs) and subsequent pDC/NK interplay.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	19559726
Pubmed	Type I IFN protects permissive macrophages from Legionella pneumophila infection through an IFN-gamma-independent pathway.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	15240719
Pubmed	Induction of APOBEC3 family proteins, a defensive maneuver underlying interferon-induced anti-HIV-1 activity.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	16418394
Pubmed	APOBEC3G upregulation by alpha interferon restricts human immunodeficiency virus type 1 infection in human peripheral plasmacytoid dendritic cells.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	18272764
Pubmed	Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	11884139
Pubmed	Double-stranded RNA analog poly(I:C) inhibits human immunodeficiency virus amplification in dendritic cells via type I interferon-mediated activation of APOBEC3G.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	19004943
Pubmed	Cytokine augmentation of human immunodeficiency virus type 1 (HIV-1) gp120-specific cellular cytotoxicity.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	2552026
Pubmed	Modulation of interferon-mediated inhibition of human immunodeficiency virus type 1 by Tat.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	7532202
Pubmed	HIV/AIDS: virus kept on a leash.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	18200012
Pubmed	Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	18200009
Pubmed	A structural basis for interferon-alpha-receptor interactions.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	17517919
Pubmed	Negative regulation of IFN-alpha/beta signaling by IFN regulatory factor 2 for homeostatic development of dendritic cells.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	14983024
Pubmed	HIV-1 Env and Nef Cooperatively Contribute to Plasmacytoid Dendritic Cell Activation via CD4-Dependent Mechanisms.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	25972534
Pubmed	Differential effects of human immunodeficiency virus type 1 envelope protein gp120 on interferon production by mononuclear cells from adults and neonates.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	7583919
Pubmed	Characterization of a mouse interferon gene locus I. Isolation of a cluster of four alpha interferon genes.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	2987811
Pubmed	Plasmacytoid dendritic cell dichotomy: identification of IFN-α producing cells as a phenotypically and functionally distinct subset.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	21172865
Pubmed	Characterization of the murine alpha interferon gene family.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	15254193
Pubmed	HIV-infected cells are major inducers of plasmacytoid dendritic cell interferon production, maturation, and migration.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	16278001
Pubmed	Recombinant glycoprotein 120 of human immunodeficiency virus is a potent interferon inducer.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	1381203
Pubmed	Induction of IFN-alpha by HIV-1 in monocyte-enriched PBMC requires gp120-CD4 interaction but not virus replication.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.71e-11	14	162	6	8345204
Pubmed	Endogenous IFN-alpha beta suppresses colony-stimulating factor (CSF)-1-stimulated macrophage DNA synthesis and mediates inhibitory effects of lipopolysaccharide and TNF-alpha.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	4.50e-11	15	162	6	8786318
Pubmed	Diversity and relatedness among the type I interferons.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	4.50e-11	15	162	6	15684736
Pubmed	Interferon alpha and Tat involvement in the immunosuppression of uninfected T cells and C-C chemokine decline in AIDS.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	4.50e-11	15	162	6	9520456
Pubmed	Are CD4 and Fas peptide identities of gp120 relevant to the molecular basis of AIDS pathogenesis?	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	4.50e-11	15	162	6	17180012
Pubmed	Role of the Akt pathway in mRNA translation of interferon-stimulated genes.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	4.50e-11	15	162	6	18339807
Pubmed	Interferon induction by HIV-1-infected cells: a possible role of sulfatides or related glycolipids.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	4.50e-11	15	162	6	8661419
Pubmed	Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	7.17e-11	16	162	6	22315404
Pubmed	Coordinate induction of interferon alpha and gamma by recombinant HIV-1 glycoprotein 120.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	7.17e-11	16	162	6	7904170
Pubmed	Sialoadhesin expressed on IFN-induced monocytes binds HIV-1 and enhances infectivity.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	7.17e-11	16	162	6	18414664
Pubmed	Cutting Edge: TLR-Dependent viral recognition along with type I IFN positive feedback signaling masks the requirement of viral replication for IFN-{alpha} production in plasmacytoid dendritic cells.	TLR9 IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	1.10e-10	17	162	6	19299691
Pubmed	Inhibitory effects of human immunodeficiency virus gp120 and Tat on CpG-A-induced inflammatory cytokines in plasmacytoid dendritic cells.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.10e-10	17	162	6	22814248
Pubmed	Characterization of the type I interferon locus and identification of novel genes.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.10e-10	17	162	6	15233997
Pubmed	Synthetic peptides corresponding to sequences in HIV envelope gp41 and gp120 enhance in vitro production of interleukin-1 and tumor necrosis factor but depress production of interferon-alpha, interferon-gamma and interleukin-2.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.65e-10	18	162	6	1905933
Pubmed	Recombinant gp120 induces IL-10 in resting peripheral blood mononuclear cells; correlation with the induction of other cytokines.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.40e-10	19	162	6	7511078
Pubmed	Induction of interleukin-10 by human immunodeficiency virus type 1 and its gp120 protein in human monocytes/macrophages.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.40e-10	19	162	6	7815507
Pubmed	Translational regulation by HIV leader RNA, TAT, and interferon-inducible enzymes.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.40e-10	19	162	6	1708818
Pubmed	Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.40e-10	19	162	6	1385305
Pubmed	Lymphocytoid choriomeningitis virus activates plasmacytoid dendritic cells and induces a cytotoxic T-cell response via MyD88.	TLR9 IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	2.40e-10	19	162	6	17942529
Pubmed	TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	3.42e-10	20	162	6	11694501
Pubmed	Human immunodeficiency virus type 1 gp120 induces anergy in human peripheral blood lymphocytes by inducing interleukin-10 production.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	3.42e-10	20	162	6	8764000
Pubmed	Human immunodeficiency virus gp120 inhibits interleukin-12 secretion by human monocytes: an indirect interleukin-10-mediated effect.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	4.77e-10	21	162	6	9108403
Pubmed	HIV-1 gp41 enhances major histocompatibility complex class I and ICAM-1 expression on H9 and U937 cells.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	6.53e-10	22	162	6	7913356
Pubmed	HIV-1 gp120 impairs the induction of B cell responses by TLR9-activated plasmacytoid dendritic cells.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	6.53e-10	22	162	6	23100517
Pubmed	Human immunodeficiency virus type 1 gp120 and other activation stimuli are highly effective in triggering alpha interferon and CC chemokine production in circulating plasmacytoid but not myeloid dendritic cells.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	6.53e-10	22	162	6	16160188
Pubmed	Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	6.53e-10	22	162	6	20574843
Pubmed	Induction of cytokines by HIV-1 and its gp120 protein in human peripheral blood monocyte/macrophages and modulation of cytokine response during differentiation.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	8.80e-10	23	162	6	9225992
Pubmed	Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis.	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	9.31e-10	11	162	5	18835032
Pubmed	High-affinity binding of 125I-labelled mouse interferon to a specific cell surface receptor.	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	9.31e-10	11	162	5	6444699
Pubmed	Structural and functional neuropathology in transgenic mice with CNS expression of IFN-alpha.	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	9.31e-10	11	162	5	10448195
Pubmed	IFN-alpha can both protect against and promote the development of type 1 diabetes.	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	9.31e-10	11	162	5	19120292
Pubmed	Effect of interferon-alpha on immediate early gene expression of murine cytomegalovirus.	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	9.31e-10	11	162	5	8389790
Pubmed	The mouse IFN-alpha (Ifa) locus: correlation of physical and linkage maps by in situ hybridization.	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	9.31e-10	11	162	5	3456887
Pubmed	Mechanism of SUMOylation-Mediated Regulation of Type I IFN Expression.	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	9.31e-10	11	162	5	36681180
Pubmed	Type I interferon dependence of plasmacytoid dendritic cell activation and migration.	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	9.31e-10	11	162	5	15795237
Pubmed	Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration.	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	9.31e-10	11	162	5	9794439
Pubmed	Recombinant rabies virus expressing IFNα1 enhanced immune responses resulting in its attenuation and stronger immunogenicity.	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	9.31e-10	11	162	5	25310498
Pubmed	PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS-STING-Mediated Interferon Response.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.17e-09	24	162	6	35037428
Pubmed	Role of HIV-1 Vpu protein for virus spread and pathogenesis.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.53e-09	25	162	6	18672082
Pubmed	LSm14A Plays a Critical Role in Antiviral Immune Responses by Regulating MITA Level in a Cell-Specific Manner.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.53e-09	25	162	6	27183626
Pubmed	Modulation of HIV-1 transcription by cytokines and chemokines.	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.53e-09	25	162	6	16375755
Pubmed	Regulation of effector and memory T-cell functions by type I interferon.	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	1.59e-09	12	162	5	21320124
Pubmed	MAVS Deficiency Is Associated With a Reduced T Cell Response Upon Secondary RSV Infection in Mice.	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	1.59e-09	12	162	5	33123150
Pubmed	A novel anti-viral role for STAT3 in IFN-α signalling responses.	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	1.59e-09	12	162	5	27988795
Pubmed	IFN-alpha-mediated suppression of low-affinity FC(epsilon) receptors on Peyer's patch lymphocytes and augmentation of soluble CD23: implications for IgE responses.	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	1.59e-09	12	162	5	8656058
Pubmed	The physical separation of Lps and Ifa loci in BXH recombinant inbred mice.	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	1.59e-09	12	162	5	2572648
Pubmed	Developmental control of IFN-alpha expression in murine embryos.	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	1.59e-09	12	162	5	7925651
Interaction	IFNA6 interactions	IFNA5 IFNA6 IFNA14 IFNA21	2.18e-07	8	153	4	int:IFNA6
Interaction	IFNA5 interactions	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16	5.60e-07	22	153	5	int:IFNA5
Interaction	IFNA14 interactions	IFNA5 IFNA6 IFNA14 IFNA21	5.41e-06	16	153	4	int:IFNA14
Interaction	IGFL3 interactions	LARGE2 ATRN MANBA NXPE3 LRP4 SORL1	2.27e-05	75	153	6	int:IGFL3
Interaction	LYZL1 interactions	LARGE2 ATRN GALNT10 MANBA ARSK STS SORL1	3.30e-05	118	153	7	int:LYZL1
Cytoband	9p22	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	2.95e-10	25	162	6	9p22
Cytoband	Ensembl 112 genes in cytogenetic band chr9p21	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21 FOCAD	3.18e-07	124	162	7	chr9p21
GeneFamily	Interferons	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	3.92e-08	32	112	6	598
GeneFamily	Phosphatidylinositol 3-kinase subunits	PIK3C2A PIK3C2G	1.04e-03	8	112	2	831
GeneFamily	Glycosyltransferase family 8	LARGE2 GYG2	1.33e-03	9	112	2	436
GeneFamily	Serpin peptidase inhibitors	SERPINB7 SERPINB10 SERPINB11	1.54e-03	37	112	3	739
GeneFamily	Phospholipases	PLB1 PLA2G4E PLCH2	2.23e-03	42	112	3	467
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	TLR9 ITGA5 ACE FCGR1A CXCR6 BST1 ENPEP IL6ST	3.14e-03	394	112	8	471
Coexpression	SHIN_B_CELL_LYMPHOMA_CLUSTER_5	IFNA2 IFNA6 IFNA14 IFNA16 IFNA21	7.41e-07	29	156	5	MM586
Coexpression	ERWIN_COHEN_PBMC_TC_83_AGE_18_45YO_NAIVE_NOT_PREVIOUSLY_IMMUNIZED_24HR_DEG_CANONICAL_PATHWAY_MEMBERS_UP	IFNA2 IFNA5 IFNA14 IFNA16 IFNA21	3.42e-06	39	156	5	M41095
Coexpression	WORSCHECH_TUMOR_REJECTION_UP	IFNA2 IFNA6 IFNA14 IFNA16 STAT6 IFNA21	8.43e-06	80	156	6	MM1229
Coexpression	LEE_CALORIE_RESTRICTION_NEOCORTEX_DN	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21	1.20e-05	85	156	6	MM684
Coexpression	LI_PBMC_MENACTRA_AGE_18_45YO_ANTI_DT_ANTIBODY_CORRELATION_PROFILE_3DY_UP	IFNA2 IFNA5 IFNA16 IFNA21	1.90e-05	27	156	4	M40935
Coexpression	IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_UP	IFNA2 IFNA5 IFNA6 IFNA14 IFNA16 IFNA21 PLCH2 ENPEP	3.91e-05	210	156	8	MM751
Coexpression	ERWIN_COHEN_PBMC_TC_83_AGE_18_45YO_RESPONDERS_PREVIOUSLY_IMMUNIZED_24HR_DEG_CANONICAL_PATHWAY_MEMBERS_UP	IFNA2 IFNA14 IFNA16 IFNA21	4.87e-05	34	156	4	M41094
ToppCell	Frontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TRAC IRAG1 TMEM71 ANGPTL2 KIAA0040 ENPEP SNTB1	1.32e-06	151	161	7	527059e47e381b2f6d63c1abb39bc0795ee3829d
ToppCell	Frontal_cortex-Endothelial-MURAL\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TRAC IRAG1 TMEM71 ANGPTL2 KIAA0040 ENPEP SNTB1	1.32e-06	151	161	7	7570372a315bc312ff57bb5f483375c401ae8787
ToppCell	Striatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)-\|Striatum / BrainAtlas - Mouse McCarroll V32	SMIM22 AOC1 NAGS DNAH14 SERPINB10 CCDC180	4.31e-06	117	161	6	26dec09112532f351fb7a2202bae84c365707b40
ToppCell	Striatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)\|Striatum / BrainAtlas - Mouse McCarroll V32	SMIM22 AOC1 NAGS DNAH14 SERPINB10 CCDC180	4.31e-06	117	161	6	db053c874e6739052dff1f91643e51b306236237
ToppCell	Striatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)--\|Striatum / BrainAtlas - Mouse McCarroll V32	SMIM22 AOC1 NAGS DNAH14 SERPINB10 CCDC180	4.31e-06	117	161	6	80780223502d18f0d86a29ff3cb74aa8235103c7
ToppCell	Striatum-Macroglia-CSF_related-EPENDYMAL\|Striatum / BrainAtlas - Mouse McCarroll V32	SMIM22 AOC1 NAGS DNAH14 SERPINB10 CCDC180	4.31e-06	117	161	6	40889f4a387846abbf54469cc4faf616bfe348d0
ToppCell	Striatum-Macroglia-CSF_related\|Striatum / BrainAtlas - Mouse McCarroll V32	SMIM22 AOC1 NAGS DNAH14 SERPINB10 CCDC180	4.31e-06	117	161	6	e12e37e393257db85f7f5c13454095c44f59d374
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|390C / Donor, Lineage, Cell class and subclass (all cells)	DMXL2 ZC3H3 FOCAD FCGR1BP ZNF684 CXCR6 CCDC180	4.72e-06	183	161	7	228092290dbb08785c4eda224e3ad03e99e10fab
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN PTCHD4 ARL4A PIK3C2G STKLD1 CCDC180 DYNC1I1	4.90e-06	184	161	7	30ca56d64c961127e26122613e35aa2b46fde2df
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CTTNBP2 FN1 LRRK1 ITGA5 ALDH1A3 CSMD1 DYNC1I1	5.84e-06	189	161	7	b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCell	C_01\|World / shred on cell type and cluster	AADAC PLB1 AOC1 ACE ARL4A HSD17B11 ENPEP	7.91e-06	198	161	7	71d38084d09a96331877384ce6346f0de4bdcef9
ToppCell	BAL-Control-cDC_0\|Control / Compartment, Disease Groups and Clusters	DMXL2 FN1 ACE FCGR1A FCGR1BP BST1 SORL1	8.17e-06	199	161	7	4518ffa51ead9da1ddf07bf048b18602e50f0f84
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DMXL2 MANBA FN1 ITGA5 STAT6 SLC22A13 SNTB1	8.17e-06	199	161	7	379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell	Cerebellum-Macroglia-CSF_related\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SMIM22 AOC1 DNAH14 CFAP61 STKLD1 CCDC180	1.07e-05	137	161	6	f004199b654143e9e766e5c5f56858089e98cf5f
ToppCell	Cerebellum-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)--\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SMIM22 AOC1 DNAH14 CFAP61 STKLD1 CCDC180	1.07e-05	137	161	6	6a5599af9d0ee1be6cac17af09aa4cd50774c683
ToppCell	Cerebellum-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SMIM22 AOC1 DNAH14 CFAP61 STKLD1 CCDC180	1.07e-05	137	161	6	01cbc9082e10ef51a1763a8b2d708eea0434490f
ToppCell	Cerebellum-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SMIM22 AOC1 DNAH14 CFAP61 STKLD1 CCDC180	1.07e-05	137	161	6	a22730b6f78b66bb3c46155af37c34e554672dee
ToppCell	Cerebellum-Macroglia-CSF_related-CHOROID_PLEXUS\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SMIM22 AOC1 DNAH14 CFAP61 STKLD1 CCDC180	1.07e-05	137	161	6	ce7c57dad201bd2164fc8b1172aca709f3f7def2
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATG16L1 TRAC DDX18 IL6ST SORL1	1.52e-05	86	161	5	79c4326df78f0a5b3ef13b2fb4e5074934536e35
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	GABRG3 CNBD1 RELN TRPV3 CSMD1 KIAA2012	1.53e-05	146	161	6	c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CTTNBP2 CLTCL1 MSANTD2 IRAG1 ANGPTL2 DYNC1I1	2.48e-05	159	161	6	7cda111bb98f1241989e49d490bdf51a712ea589
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)\|Striatum / BrainAtlas - Mouse McCarroll V32	TRAC IRAG1 CXCR6 ENPEP SNTB1	2.59e-05	96	161	5	d98df92856840602a82d3f050bf0a1543445cac0
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)-\|Striatum / BrainAtlas - Mouse McCarroll V32	TRAC IRAG1 CXCR6 ENPEP SNTB1	2.59e-05	96	161	5	bf62c29da66aa3eefdc59337dfb3cd0467f04f10
ToppCell	343B-Epithelial_cells-Epithelial-H_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RELN PLB1 GGH PLCH2 LRP4 ALDH1A3	2.66e-05	161	161	6	da9eecf919866a9c579d7a707a996cf335213134
ToppCell	343B-Epithelial_cells-Epithelial-H_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RELN PLB1 GGH PLCH2 LRP4 ALDH1A3	2.66e-05	161	161	6	d431625c32f59a6b552191f3adc5198bd16ad5cf
ToppCell	C_02\|World / shred on cell type and cluster	AADAC PLB1 ACE ARL4A PIK3C2G ENPEP	3.06e-05	165	161	6	a456c2c9ffe8dc91e17cac84ba87b88e016f8e6d
ToppCell	droplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ERO1A CAPN3 TMEM71 BLM FCER1A KIAA2012	3.38e-05	168	161	6	0e99ecd94ab8e5372e30433d7d0aa76b4d54257a
ToppCell	droplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ERO1A CAPN3 TMEM71 BLM FCER1A KIAA2012	3.38e-05	168	161	6	34722e14f28313f2e4644b3c1861ef12958cee9f
ToppCell	Posterior_cortex-Endothelial-MURAL\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TRAC IRAG1 ANGPTL2 KIAA0040 ENPEP SNTB1	3.50e-05	169	161	6	0ae65daf092396b71f790b65c7a2feed90397417
ToppCell	droplet-Lung-nan-18m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERO1A CAPN3 TMEM71 BLM FCER1A KIAA2012	3.50e-05	169	161	6	f2e20049a17eee533d49bd5f24a51962d123d132
ToppCell	Posterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TRAC IRAG1 ANGPTL2 KIAA0040 ENPEP SNTB1	3.50e-05	169	161	6	8cd70ce27b1cecb83f8a376230e7ef41b079b124
ToppCell	droplet-Lung-nan-18m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERO1A CAPN3 TMEM71 BLM FCER1A KIAA2012	3.50e-05	169	161	6	4c6892551e9dec94fc62b3beab1e6d424639a1e9
ToppCell	droplet-Spleen-nan-21m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 ACE GGH SERPINB10 FCER1A FCGR1BP	3.62e-05	170	161	6	03cb4e508356f85372a588c8d1c6babf2a012683
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN FN1 ST6GAL1 ITGA5 F8 BLM	3.86e-05	172	161	6	c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ATRN DMXL2 FUZ BLM FOCAD KIAA0040	4.12e-05	174	161	6	58300d64d3b6fd9ba1b6c87ea83b2777eb6be2f4
ToppCell	droplet-Fat-Mat-18m-Hematologic-monocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIN1 ERO1A TMEM71 FCER1A KIAA2012 HOMEZ	4.39e-05	176	161	6	867936a20f73f638055c19c8d88834aa2cc657cf
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-CD45____plasma_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MROH2A ST6GAL1 UBALD2 TMEM214 MEI1 GGTA1	4.53e-05	177	161	6	41cbb2c109eaa7be366fc0510cce64abc06837b4
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	GALNT10 FN1 ITGA5 IRAG1 ANGPTL2 ALDH1A3	4.67e-05	178	161	6	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2\|Striatum / BrainAtlas - Mouse McCarroll V32	TMEM71 ANGPTL2 ENPEP LMNTD1 SNTB1	5.43e-05	112	161	5	88fcd0dc12b5c00804381fb7dd59a6a2a9f37419
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-\|Striatum / BrainAtlas - Mouse McCarroll V32	TMEM71 ANGPTL2 ENPEP LMNTD1 SNTB1	5.43e-05	112	161	5	fd4cc5190626cb262aae0a7f04559b0e9757270e
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)\|Striatum / BrainAtlas - Mouse McCarroll V32	TMEM71 ANGPTL2 ENPEP LMNTD1 SNTB1	5.43e-05	112	161	5	d652e6fae433a6b56bf2a448fba2cf6c5e558905
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ATRN PLB1 ST6GAL1 DNAAF9 LRRK1 NAV2	5.79e-05	185	161	6	8207f9eff113eed429e961748c6b17d672a13b33
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	DMXL2 FOCAD FCGR1BP ZNF684 PIK3C2A CCDC180	6.14e-05	187	161	6	1eed2c1a05e80a7c8f639437c117afe0c18dfb0c
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TRAC PLA2G4E ACE IL6ST SENP7 SORL1	6.14e-05	187	161	6	e61c1755531469dd3850c9740474b5ad4e0499c1
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCC4 CTTNBP2 AOC1 LRRK1 PEA15 SORL1	6.33e-05	188	161	6	9fc3819aae5a2b2534cb131d467435b5cfc420d6
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ABCC4 CTTNBP2 AOC1 LRRK1 PEA15 SORL1	6.33e-05	188	161	6	5e5d779ea079d3b2a1ef650b06b9f5cc1ffef5e7
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CTTNBP2 FN1 LRRK1 ITGA5 ALDH1A3 CSMD1	6.52e-05	189	161	6	c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CTTNBP2 FN1 LRRK1 ITGA5 ALDH1A3 CSMD1	6.71e-05	190	161	6	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	Children_(3_yrs)-Immune-monocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DMXL2 PLB1 LRRK1 TMEM71 FCER1A SORL1	7.31e-05	193	161	6	58e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCell	droplet-Bladder-nan-3m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRN SMIM22 ABCC4 PLCH2 NIPAL1 SORL1	7.31e-05	193	161	6	268925bfe85fb94a93a4ff8fe078d692df888140
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SMIM22 AOC1 ST6GAL1 NXPE1 SEMA4G SORL1	7.53e-05	194	161	6	07d8e38cbc2c7f0564c14f7c365f345f901b73b2
ToppCell	Control-Classical_Monocyte\|Control / Disease condition and Cell class	DMXL2 TMEM71 FCGR1A FCGR1BP BST1 SORL1	7.53e-05	194	161	6	9e33e1b54b4114f9e6981819834bb796ed7192b5
ToppCell	myeloid-Monocyte-CD14+_Monocyte\|myeloid / Lineage, cell class and subclass	DMXL2 UBALD2 SERPINB10 FCGR1A FCGR1BP BST1	7.74e-05	195	161	6	15ba9c5f6ecb6ae2c603e6b036eb92b00b46f13f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRG3 FOCAD PLEKHA5 CSMD1 TARBP1 DYNC1I1	7.96e-05	196	161	6	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	NXPE1 ABCA8 ANGPTL2 LRP4 ALDH1A3 DYNC1I1	7.96e-05	196	161	6	57df2a57b35be9851ac0b1e5731baa53052511f0
ToppCell	Thalamus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	SMIM22 AOC1 NAGS DNAH14 CCDC180	8.16e-05	122	161	5	aca079f2f033cc1ac13c4ee02d490b6a514cbd5c
ToppCell	Thalamus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)--\|Thalamus / BrainAtlas - Mouse McCarroll V32	SMIM22 AOC1 NAGS DNAH14 CCDC180	8.16e-05	122	161	5	ac38130010f76648757eac700a8039f3960ddde3
ToppCell	Thalamus-Macroglia-CSF_related-EPENDYMAL\|Thalamus / BrainAtlas - Mouse McCarroll V32	SMIM22 AOC1 NAGS DNAH14 CCDC180	8.16e-05	122	161	5	7ab0b63244116e74c5783c3293cf08224d094d0a
ToppCell	Thalamus-Macroglia-CSF_related\|Thalamus / BrainAtlas - Mouse McCarroll V32	SMIM22 AOC1 NAGS DNAH14 CCDC180	8.16e-05	122	161	5	eb944243424460bf5c66aced3ed7b7a1b6486ac7
ToppCell	Thalamus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)\|Thalamus / BrainAtlas - Mouse McCarroll V32	SMIM22 AOC1 NAGS DNAH14 CCDC180	8.16e-05	122	161	5	9b0d6b0a394560ff5aadcd3b21519c2393e6def8
ToppCell	Enterocyte\|World / shred on cell type and cluster	AADAC PLB1 AOC1 ACE ARL4A ENPEP	8.19e-05	197	161	6	1dd980fd066aef21694395a4b69df938501d9631
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRG3 FOCAD PLEKHA5 CSMD1 TARBP1 DYNC1I1	8.42e-05	198	161	6	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Parenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CLTCL1 GRID1 IRAG1 BLM PIK3C2G ENPEP	8.42e-05	198	161	6	882710bd6215e299257dd3df234292db9a2823ba
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRG3 FOCAD PLEKHA5 CSMD1 TARBP1 DYNC1I1	8.42e-05	198	161	6	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SMIM22 AADAC AOC1 ACE HSD17B11 ENPEP	8.42e-05	198	161	6	2967fb2d94662997bfe932ac299c80d6f182fb48
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SMIM22 AADAC AOC1 ACE HSD17B11 ENPEP	8.42e-05	198	161	6	222a060c2c63d30da34e4b71c37aa27a048d7d09
ToppCell	COVID-19_Mild-Classical_Monocyte\|COVID-19_Mild / Disease condition and Cell class	DMXL2 ITGA5 FCGR1A FCGR1BP BST1 SORL1	8.42e-05	198	161	6	30ada3de865b6fb2b14196a1cbfd4740c6a57ce3
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	GABRG3 FOCAD PLEKHA5 CSMD1 TARBP1 DYNC1I1	8.90e-05	200	161	6	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Bronchial-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RELN FN1 ITGA5 TIPARP GYG2 DYNC1I1	8.90e-05	200	161	6	b7b9441fa7ab0d43741a2ebd5ec1a48d537c6d47
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Goblet\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SERPINB7 SMIM22 ERO1A ST6GAL1 SERPINB11 ALDH1A3	8.90e-05	200	161	6	133853d0f55c63ebe94dd54151f9f1f90650a0d8
ToppCell	Bronchial-NucSeq-Stromal-Chondrocytic-Chondrocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RELN FN1 ITGA5 TIPARP GYG2 DYNC1I1	8.90e-05	200	161	6	7c673ad0ea503ebd196579684d25d5f9e6a41030
Drug	pyran	AADAC CTTNBP2 IFNA2 IFNA5 IFNA6	5.17e-06	37	156	5	CID000033703
Drug	C12063	SERPINB7 MANBA FN1 ERO1A CAPN3 ACE IFNA2 IFNA5 IFNA6 STS FCER1A ENTPD6 SORL1	8.56e-06	429	156	13	CID005282055
Drug	Palmatine chloride [3486-67-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A	USP34 NXPE3 WDR91 STS BAZ2A NAV2 ARHGEF2 SENP7 CAPN15	8.67e-06	196	156	9	2795_DN
Disease	level of ADP-ribose pyrophosphatase, mitochondrial in blood serum	NUDT9 HSD17B11	2.67e-05	2	153	2	OBA_2042674
Disease	immunoglobulin E measurement	STAT6 FCER1A	2.67e-05	2	153	2	EFO_0020464
Disease	bitter alcoholic beverage consumption measurement	FBXO40 RELN STAT6 CSMD1 SENP7 SORL1	7.03e-05	133	153	6	EFO_0010092
Disease	response to methotrexate, juvenile idiopathic arthritis	CTTNBP2 ENTHD1 CSMD1	1.25e-04	19	153	3	EFO_0002609, GO_0031427
Disease	ADP-ribose pyrophosphatase, mitochondrial measurement	NUDT9 HSD17B11	1.59e-04	4	153	2	EFO_0801349
Disease	alkaline phosphatase measurement	USP34 ATG16L1 DNAJC13 AOC1 NRBF2 MANBA U2SURP ST6GAL1 PKD1L3 WDR91 ZNF45 ENTPD6 STKLD1 SENP7 HOMEZ	2.70e-04	1015	153	15	EFO_0004533
Disease	Rheumatoid Arthritis	ABCC4 PLB1 GIN1 GGH STS IL6ST	3.04e-04	174	153	6	C0003873
Disease	SPARC-like protein 1 measurement	NUDT9 HSD17B11	3.95e-04	6	153	2	EFO_0008289
Disease	IgA glomerulonephritis (is_implicated_in)	SERPINB7 TLR9 ACE	5.01e-04	30	153	3	DOID:2986 (is_implicated_in)
Disease	proteinuria (is_implicated_in)	TLR9 ACE	5.51e-04	7	153	2	DOID:576 (is_implicated_in)
Disease	behavioural disinhibition measurement	CTTNBP2 FN1 ENTHD1 CSMD1	6.35e-04	75	153	4	EFO_0006946
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CAPN3 SLC6A5 SNTB1	8.61e-04	36	153	3	DOID:11723 (implicated_via_orthology)
Disease	renovascular hypertension (implicated_via_orthology)	FN1 ACE	9.39e-04	9	153	2	DOID:1591 (implicated_via_orthology)
Disease	Crohn's disease of large bowel	ATG16L1 FN1 TLR9	1.55e-03	44	153	3	C0156147
Disease	IIeocolitis	ATG16L1 FN1 TLR9	1.55e-03	44	153	3	C0949272
Disease	Crohn's disease of the ileum	ATG16L1 FN1 TLR9	1.55e-03	44	153	3	C0267380
Disease	Regional enteritis	ATG16L1 FN1 TLR9	1.55e-03	44	153	3	C0678202
Disease	cannabis dependence measurement	MEI1 DDX18 CSMD1	1.99e-03	48	153	3	EFO_0008457
Disease	mood disorder	RELN SORL1	2.01e-03	13	153	2	EFO_0004247
Disease	Crohn Disease	ATG16L1 FN1 TLR9	2.24e-03	50	153	3	C0010346
Disease	Glioblastoma Multiforme	FN1 IFNA2 CCNH STKLD1	2.71e-03	111	153	4	C1621958
Disease	Alcoholic Intoxication, Chronic	GABRG3 ZNF699 ACE TIPARP GGH KIAA0040	2.82e-03	268	153	6	C0001973
Disease	Colorectal Neoplasms	ABCC4 GRID1 ABCA8 IFNA2 GGH IL6ST	3.31e-03	277	153	6	C0009404
Disease	Renal Insufficiency	ACE IFNA2	3.45e-03	17	153	2	C1565489
Disease	renal fibrosis (implicated_via_orthology)	ACE STAT6	3.45e-03	17	153	2	DOID:0050855 (implicated_via_orthology)
Disease	age at onset, Parkinson disease	GABRG3 KLHDC1	3.87e-03	18	153	2	EFO_0004847, MONDO_0005180
Disease	body fat percentage	DMXL2 RELN AOC1 TEX10 ZC3H3 KIAA2012 SENP7 HOMEZ	4.06e-03	488	153	8	EFO_0007800
Disease	facial asymmetry measurement	CNBD1 KLHDC1	4.31e-03	19	153	2	EFO_0009751
Disease	urate measurement, bone density	PLB1 GRID1 OGDH ABCA8 DNAH14 TIPARP ARL4A FCGR1BP RABGAP1L	5.14e-03	619	153	9	EFO_0003923, EFO_0004531

Protein segments in the cluster

Peptide	Gene	Start	Entry
LFTHLTESWNNFKGL	ARSK	91	Q6UWY0
FFEVSSTKWFHNGSL	FCER1A	56	P12319
STKWFHNGSLSEETN	FCER1A	61	P12319
SLFWENSHLLVNSFA	BST1	106	Q10588
EWTHSNFSSKEIGFQ	CFAP61	991	Q8NHU2
SQKRHWTFSSEEQLA	CCNH	6	P51946
TKQQWFDLFSDVHAV	CUL5	36	Q93034
HQWKSSEDNSKTFSA	CXCR6	316	O00574
DWFNATSSKVNATFS	CSMD1	3376	Q96PZ7
LFQSVAASWAHDTNI	ACE	61	P12821
PVESSHLFKFVNWSS	AADAC	271	P22760
VLSKQHSSSINAVAW	ATG16L1	571	Q676U5
QHDLSQSAFLSWLSQ	BAZ2A	1261	Q9UIF9
SWSLAVDSSFLQQHK	ARHGEF2	216	Q92974
FTKIFINNEWHESKS	ALDH1A3	31	P47895
VTLGNSKTVTFHFWD	ARL4A	61	P40617
DSFTWHNGKQFTTLD	ANGPTL2	406	Q9UKU9
HWLNNKEFHFTSSTE	DMXL2	391	Q8TDJ6
LNQWAVTFADKSAFT	DMXL2	621	Q8TDJ6
LSNQELKAVHSFLWS	AOC1	36	P19801
TLADQTEWQSSHLFK	CCDC180	506	Q9P1Z9
SHFQCEFSSISKWSE	C1orf147	181	Q96MC9
FEVNVLAHFWTTKAF	HSD17B11	141	Q8NBQ5
LHFQANTKTFSKDWV	MSANTD2	491	Q6P1R3
FSHISQVWSFQKKQT	RNF212B	71	A8MTL3
QDTKLHVFDANTLTW	RABEPK	166	Q7Z6M1
SELWALFAHFSDTQA	LARGE2	211	Q8N3Y3
LNEFTSKSRELSWHQ	PIK3C2G	86	O75747
SSNVNSIYHTVWKFF	TIPARP	336	Q7Z3E1
DLNEWLASNTTTFFH	MOB2	51	Q70IA6
HSVFQISSWAARFKA	OR52Z1P	206	P0C646
QAFLSDWTASKGTHS	CAPN15	1056	O75808
FWTLSHQQLSSTSFK	ENTHD1	446	Q8IYW4
FFHWNSNLTILKTNI	FCGR1BP	146	Q92637
QTFNLFSTKNSSAAW	IFNA14	86	P01570
FSHDFWSTEINQLIA	MGAT2	151	Q10469
AFITDHVNSLIDQWF	LRRK1	1131	Q38SD2
KSSLNFEKHSENFAW	GPBP1	21	Q86WP2
QWLFEHTNSTVLEKF	GALNT10	586	Q86SR1
KNFNLNITWAASFSA	ATRN	1201	O75882
AFFSSIWDTILTKHQ	KIAA0040	6	Q15053
QTFNLFSTKDSSATW	IFNA21	86	P01568
IQISFHKEWFSANIS	BPIFA3	106	Q9BQP9
FSHLFVTSSFDWTVK	DYNC1I1	501	O14576
QIFNLFTTKDSSAAW	IFNA1;	86	P01562
ENFKASITSSASLWH	IRAG1	566	Q9Y6F6
SDVWTLQILHSASFF	OR14C36	16	Q8NHC7
RNSFSSSWFHLNTNV	NUDT9	36	Q9BW91
LQFTIFAAHGISSNW	PIK3C2A	686	O00443
TGSAWFSFLESHNKL	PEA15	41	Q15121
QTFNLFSTKDSSATW	IFNA5	86	P01569
AASKSQLLAHQFIWN	PI4KA	1676	P42356
QDKNNASQHSWSLFL	KIAA2012	46	Q0VF49
ASQHSWSLFLPKTFS	KIAA2012	51	Q0VF49
NSTVTVWAAASEAKH	LMNTD1	201	Q8N9Z9
ISSSQDGHQWTLFFQ	F8	2281	P00451
FKHSDGSFSNKQWIF	NAGS	486	Q8N159
WDSIATALSLNHKTF	ENPEP	636	Q07075
LSHLSFVDVWFSSNV	OR5M3	61	Q8NGP4
FDFSWSKISDIQSQL	DDX18	551	Q9NVP1
TTSHSQAFNFWDLIK	MFSD6	426	Q6ZSS7
TATASSTWQKFAANT	NRBF2	236	Q96F24
IQAAKNSWFSKTLNS	RABGAP1L	216	B7ZAP0
AETWDFHVSASTFLQ	RELN	1651	P78509
SAWLLTASFSAQQHK	MEI1	1011	Q5TIA1
EINSHSLFSKWFSES	TRIP13	211	Q15645
QDLHSEAWFLFLTTS	ABCC4	931	O15439
FSLNLLDAWNLSHTS	PLA2G4E	581	Q3MJ16
NSFFRNWSTTDIHKH	GYG2	201	O15488
SQSLQLHFRVWAKTF	ITGA5	931	P08648
SVHKSWDIFFRNTNA	OGDH	71	Q02218
VTHNFQVDFVWKSTS	UPF1	416	Q92900
TNFTLKSEWATHKFA	IL6ST	156	P40189
LFNTHLQKSFVSSNW	BLM	491	P54132
QGTSEITSFSHQWAK	BRCA2	1551	P51587
TANFHKWSLSVKNFT	GGH	191	Q92820
TIFRNSKTAEAHWIT	GABRG3	131	Q99928
TVFWKSGNALFHAST	EIF3A	281	Q14152
WDDFSKAVSQALTNH	CTTNBP2	1006	Q8WZ74
QTHFHTIQKSSWDAF	FBXL3	266	Q9UKT7
DFSDITANSFTVHWI	FN1	1456	P02751
KISFNADVHASLQWN	COX11	151	Q9Y6N1
DWFLQHFAISSISQE	DNAAF9	706	Q5TEA3
ANHILNSKSISNWTF	ADGRF2	241	Q8IZF7
SSFAVDFWLQTHLFQ	DNAJC13	1526	O75165
DWFHQVFVSSVVSKS	DNAH14	2736	Q0VDD8
AVLQWTKHDDSSDNF	ERO1A	151	Q96HE7
STEDWSFNSKFSLHR	MANBA	571	O00462
QFSSLFSKIKSWEFN	FBXO40	641	Q9UH90
IFNLFSTKDSSAAWD	IFNA2	86	P01563
FFHWNSNLTILKTNI	FCGR1A	146	P12314
TNLASKDSHWVFVNE	GRID1	246	Q9ULK0
NDVHIFDTKTQTWFQ	KLHDC1	171	Q8N7A1
HVFFWEKSSSQIIQF	DCAF8L1	461	A6NGE4
QSDFWQHLQSSGLSK	HOMEZ	216	Q8IX15
FFSLQSGNTWENKTL	GPR22	181	Q99680
FTKSNHRNEFWSALL	CAPN3	191	P20807
FWCNFTLTKHLNISS	ERVFC1	331	P60507
AVAWVKNHTFNLSAA	SLC22A13	51	Q9Y226
IFLLHAFKNTDITWS	NIPAL1	351	Q6NVV3
NFKVQVLSFLWTHTQ	FOCAD	686	Q5VW36
ENTTVVWKSFHDSIT	FUZ	66	Q9BT04
SISVHYWNNSAKSLF	NXPE1	41	Q8N323
QTFNLFSTKDSSVAW	IFNA6	86	P05013
QHDKASVTWIAFFLQ	MROH2A	1096	A6NES4
IIFISNAWAVTNHFS	TAS2R20	81	P59543
INHFSNWLATSLSIF	TAS2R46	91	P59540
SKRSHAILFFWVSSD	SENP7	581	Q9BQF6
VFTIFGSNKENVHSW	SORL1	596	Q92673
KDSATAQAWFSAIHS	SNTB1	281	Q13884
FNLSTSKSWLHGSIF	TMEM71	121	Q6P5X7
VWKDAATQIFFSLSA	SLC6A5	466	Q9Y345
KWHRATATQAFFSIT	ENTPD6	61	O75354
NSTEGSFLWIYHSKN	GGTA1	26	Q4G0N0
TFTFHQFSQWLKTLT	LMF2	351	Q9BU23
KNTVVAIAVWSHFST	NXPE3	436	Q969Y0
FNHSWKTSANISALI	TAF1A	216	Q15573
QTFNLFSTKDSSAAW	IFNA16	86	P05015
WDDHLSAVSFAFNVT	GIN1	261	Q9NXP7
SLASFSLWRDFHKTS	PTCHD4	216	Q6ZW05
WEKSSVDNFVSRLHS	NAV2	1636	Q8IVL1
HQAIWKTFSHQFSEI	PKD1L3	1311	Q7Z443
HPQNSTSIWKAFFFT	STS	456	P08842
SHQFFQSTWDTVAFI	SMIM22	21	K7EJ46
ASFQVWNKDSSSKNL	ST6GAL1	91	P15907
FSSKSHSRAASALWN	PLB1	656	Q6P1J6
KQLNSGTFHEWTSSS	SERPINB11	261	Q96P15
LQHISSWEFSQAALF	STRC	1606	Q7RTU9
FKSNSAVAWSNKSDF	TRAC	56	P01848
AQAVTTSKWELFDQH	U2SURP	771	O15042
FLKSSFWSQTQKTDH	ABCA8	436	O94911
FWSSSQHISIEGQKE	BRCC3	191	P46736
DHTWTVSFFSKAGQL	CLTCL1	1431	P53675
SFISQSFHSFIWSEE	CNBD1	226	Q8NA66
SFHSFIWSEEFKNST	CNBD1	231	Q8NA66
FAAQIFGLSNHLVWS	PAICS	386	P22234
HTIQWARDKFESSFS	UBA6	636	A0AVT1
TFTWNSSFNQHVKSH	ZNF684	251	Q5T5D7
TFKTAFSLWSHEQTH	ZBTB21	1051	Q9ULJ3
SFRWQSEASSKDHAS	ZC3H3	391	Q8IXZ2
KAFAWSSNLSQHQRI	ZNF497	141	Q6ZNH5
THFYAAFTLSTQWKT	SEMA4G	316	Q9NTN9
WKLQSFSFSNTASLK	MINDY4	431	Q4G0A6
NLSANALKTVDHSWF	TLR9	731	Q9NR96
ALNFSFSQKSDIWSL	STKLD1	206	Q8NE28
FKSNSAVAWSNKSDF	TRA	191	P0DTU3
ASSWQVSSFSETKAH	PLCH2	646	O75038
AFQHRSVSWSQFNKE	STAT6	491	P42226
SLQLAWAHTNATVSF	TMEM214	561	Q6NUQ4
EWQFNHFSKLTSSRL	USP17L13	11	C9JLJ4
FVEHFSSWLSLELFS	KRT10-AS1	61	Q8N816
TSNSIFINWKEHAND	TEX10	261	Q9NXF1
WQSAFTKSETINCHF	SERPINB7	181	O75635
FAVVHFASRQWKVTS	MRPL21	96	Q7Z2W9
WNFQKSTSSFNFTIT	TRAV19	86	A0A0A6YYK7
HWQFETALSTFFQET	UBALD2	36	Q8IYN6
SDLQSILSDAWFHFV	TRPV3	511	Q8NET8
DWQFNHFSKLTSSRL	USP17L7	11	P0C7H9
FNSWDQFKDHLVIHT	ZNF131	401	P52739
SDKQFQHLSVSAEQW	TARBP1	1501	Q13395
AIATNHNKQALLSFW	USP34	2791	Q70CQ2
FKRNDSWFSSLHENQ	ZNF699	126	Q32M78
VFFINEEAKSTTWLH	PLEKHA5	26	Q9HAU0
WADTFIVSLHNFLSV	WDR91	151	A4D1P6
KSFSWSSHLQINQRA	ZNF45	171	Q02386
ESAQGKNIFFSSWSI	SERPINB10	21	P48595
VLTNGKSFWTRHFSA	TMEM145	151	Q8NBT3
HWQFETALSAFFQET	UBALD1	36	Q8TB05
TDWHTKSINSANKFT	LRP4	656	O75096