Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
HumanPhenoPostaxial polysyndactyly of foot

NEK1 DDX59

1.78e-052222HP:0005817
DomainROC_dom

DAPK1 LRRK1

9.24e-054742IPR020859
DomainROC

DAPK1 LRRK1

9.24e-054742PS51424
DomainTSP_1

ADAMTS12 THBS1 THBS2 ADAMTS20

1.13e-0463744PF00090
DomainTSP1

ADAMTS12 THBS1 THBS2 ADAMTS20

1.28e-0465744SM00209
DomainTSP1_rpt

ADAMTS12 THBS1 THBS2 ADAMTS20

1.28e-0465744IPR000884
DomainTSP1

ADAMTS12 THBS1 THBS2 ADAMTS20

1.28e-0465744PS50092
DomainTSP_3

THBS1 THBS2

1.54e-045742PF02412
DomainTSP3

THBS1 THBS2

1.54e-045742PS51234
DomainTSP_CTER

THBS1 THBS2

1.54e-045742PS51236
Domain-

THBS1 THBS2

1.54e-0457424.10.1080.10
DomainThrombospondin_C

THBS1 THBS2

1.54e-045742IPR008859
DomainTSP_C

THBS1 THBS2

1.54e-045742PF05735
DomainThrombospondin_3_rpt

THBS1 THBS2

1.54e-045742IPR017897
DomainThrombospondin_3-like_rpt

THBS1 THBS2

1.54e-045742IPR003367
DomainTSP_type-3_rpt

THBS1 THBS2

1.54e-045742IPR028974
DomainHelicase_C

DDX59 HLTF SMARCAD1 ASCC3

8.61e-04107744PF00271
DomainHELICc

DDX59 HLTF SMARCAD1 ASCC3

8.61e-04107744SM00490
DomainHelicase_C

DDX59 HLTF SMARCAD1 ASCC3

8.91e-04108744IPR001650
DomainHELICASE_CTER

DDX59 HLTF SMARCAD1 ASCC3

9.23e-04109744PS51194
DomainHELICASE_ATP_BIND_1

DDX59 HLTF SMARCAD1 ASCC3

9.23e-04109744PS51192
DomainDEXDc

DDX59 HLTF SMARCAD1 ASCC3

9.23e-04109744SM00487
DomainHelicase_ATP-bd

DDX59 HLTF SMARCAD1 ASCC3

9.55e-04110744IPR014001
DomainUDENN

DENND1B DENND4C

1.79e-0316742PS50946
DomainDDENN

DENND1B DENND4C

1.79e-0316742PS50947
DomainDENN

DENND1B DENND4C

1.79e-0316742SM00799
DomaindDENN

DENND1B DENND4C

1.79e-0316742SM00801
DomainDENN

DENND1B DENND4C

1.79e-0316742PF02141
DomaindDENN_dom

DENND1B DENND4C

1.79e-0316742IPR005112
DomainuDENN_dom

DENND1B DENND4C

1.79e-0316742IPR005113
DomaindDENN

DENND1B DENND4C

1.79e-0316742PF03455
DomainDENN

DENND1B DENND4C

1.79e-0316742PS50211
DomainDENN_dom

DENND1B DENND4C

1.79e-0316742IPR001194
DomainADAM_spacer1

ADAMTS12 ADAMTS20

3.71e-0323742IPR010294
DomainActinin_actin-bd_CS

DST LCP1

3.71e-0323742IPR001589
DomainTSPN

THBS1 THBS2

3.71e-0323742SM00210
DomainSpectrin

DST SPTA1

3.71e-0323742PF00435
DomainADAM_spacer1

ADAMTS12 ADAMTS20

3.71e-0323742PF05986
DomainACTININ_2

DST LCP1

3.71e-0323742PS00020
DomainACTININ_1

DST LCP1

3.71e-0323742PS00019
DomainPeptidase_M12B_ADAM-TS

ADAMTS12 ADAMTS20

4.04e-0324742IPR013273
DomainVWC

THBS1 THBS2

5.48e-0328742PF00093
DomainKinase-like_dom

NEK1 DST SIK2 LMTK2 DAPK1 LRRK1 GSK3A

5.61e-03542747IPR011009
DomainSpectrin_repeat

DST SPTA1

5.87e-0329742IPR002017
DomainP-loop_NTPase

ABCA3 DDX59 MYO19 ARL13B HLTF DAPK1 SMARCAD1 LRRK1 ASCC3

6.18e-03848749IPR027417
DomainSNF2_N

HLTF SMARCAD1

7.11e-0332742IPR000330
DomainSpectrin/alpha-actinin

DST SPTA1

7.11e-0332742IPR018159
DomainSNF2_N

HLTF SMARCAD1

7.11e-0332742PF00176
DomainSPEC

DST SPTA1

7.11e-0332742SM00150
PathwayREACTOME_DISEASES_OF_METABOLISM

ADAMTS12 THBS1 THBS2 ABCA3 ACACA CSPG5 ADAMTS20 ALG11

1.14e-05250618M27554
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS12 THBS1 THBS2 ADAMTS20

2.33e-0539614M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS12 THBS1 THBS2 ADAMTS20

2.33e-0539614MM15165
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS12 THBS1 THBS2 CSPG5 ADAMTS20 ALG11

3.44e-05143616M27275
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS12 THBS1 THBS2 ADAMTS20

2.10e-0468614M27303
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

NEK1 DST ACACA AKAP11 ASCC3 DENND4C GSK3A SPAG5 ADD3

9.74e-1020977936779422
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NEK1 DST DENND1B ACACA AASS EIF5 SIK2 LMTK2 NCOA7 AKAP11 DENND4C GSK3A KIAA0753

5.11e-08861771336931259
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RLF NEK1 DST ACACA ATF7IP ASCC3 DENND4C SPAG5

4.15e-0641877834709266
Pubmed

Induced thrombospondin expression in the mouse pancreas during pancreatic injury.

THBS1 THBS2

4.84e-06277216181801
Pubmed

Immunochemical analysis of the structure of the signature domains of thrombospondin-1 and thrombospondin-2 in low calcium concentrations.

THBS1 THBS2

4.84e-06277217620335
Pubmed

Human cytomegalovirus infection modulates thrombospondins 1 and 2 in primary fetal astrocytes.

THBS1 THBS2

4.84e-06277223660684
Pubmed

Increased excitatory connectivity and epileptiform activity in thrombospondin1/2 knockout mice following cortical trauma.

THBS1 THBS2

4.84e-06277239122122
Pubmed

Compound deletion of thrombospondin-1 and -2 results in a skeletal phenotype not predicted by the single gene knockouts.

THBS1 THBS2

4.84e-06277234425286
Pubmed

Thrombospondin-1 (TSP1)-null and TSP2-null mice exhibit lower intraocular pressures.

THBS1 THBS2

4.84e-06277222930728
Pubmed

Modulation of thrombospondin expression during differentiation of embryonal carcinoma cells.

THBS1 THBS2

4.84e-0627728126073
Pubmed

THBS1 and THBS2 Enhance the In Vitro Proliferation, Adhesion, Migration and Invasion of Intrahepatic Cholangiocarcinoma Cells.

THBS1 THBS2

4.84e-06277238339060
Pubmed

Circulating Levels of Thrombospondin-1 and Thrombospondin-2 in Patients with Temporal Lobe Epilepsy Before and After Surgery.

THBS1 THBS2

4.84e-06277233372257
Pubmed

An association study of thrombospondin 1 and 2 SNPs with coronary artery disease and myocardial infarction among South Indians.

THBS1 THBS2

4.84e-06277221762961
Pubmed

Restricted localization of thrombospondin-2 protein during mouse embryogenesis: a comparison to thrombospondin-1.

THBS1 THBS2

4.84e-0627729694593
Pubmed

The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice.

THBS1 THBS2

4.84e-06277212213711
Pubmed

Thrombospondin expression in aldosterone-producing adenomas.

THBS1 THBS2

4.84e-06277212358136
Pubmed

A second, expressed thrombospondin gene (Thbs2) exists in the mouse genome.

THBS1 THBS2

4.84e-0627721712771
Pubmed

Expression of thrombospondin-1 in ischemia-induced retinal neovascularization.

THBS1 THBS2

4.84e-06277210027393
Pubmed

Contribution of Thrombospondin-1 and -2 to Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome.

THBS1 THBS2

4.84e-06277233981184
Pubmed

Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke.

THBS1 THBS2

4.84e-06277218594557
Pubmed

Roles of thrombospondin-1 and -2 in regulating corneal and iris angiogenesis.

THBS1 THBS2

4.84e-06277215037577
Pubmed

TSP1 and TSP2 Have Unique and Overlapping Roles in Protecting against Noise-Induced Auditory Synaptopathy.

THBS1 THBS2

4.84e-06277230928339
Pubmed

Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization.

THBS1 THBS2

4.84e-06277217143334
Pubmed

Circulating Levels of Thrombospondin-1 and Thrombospondin-2 in Patients with Common Brain Tumors.

THBS1 THBS2

4.84e-06277233759165
Pubmed

Increased sensitivity to kindling in mice lacking TSP1.

THBS1 THBS2

1.45e-05377226241338
Pubmed

Expression and function of thrombospondin-1 in myelinating glial cells of the central nervous system.

THBS1 THBS2

1.45e-0537729373030
Pubmed

Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury.

THBS1 THBS2

1.45e-05377218787106
Pubmed

Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells.

THBS1 THBS2

1.45e-05377218032585
Pubmed

Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis.

THBS1 THBS2

1.45e-05377219818485
Pubmed

EWS/FLI1 regulates tumor angiogenesis in Ewing's sarcoma via suppression of thrombospondins.

THBS1 THBS2

1.45e-05377217638877
Pubmed

TSP1 and TSP2 deficiencies affect LOX protein distribution in the femoral diaphysis and pro-peptide removal in marrow-derived mesenchymal stem cells in vitro.

THBS1 THBS2

1.45e-05377230939949
Pubmed

Interactions between CD47 and thrombospondin reduce inflammation.

THBS1 THBS2

1.45e-05377217442977
Pubmed

Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses.

THBS1 THBS2

1.45e-05377219004835
Pubmed

Thrombospondin is a tight-binding competitive inhibitor of neutrophil elastase.

THBS1 THBS2

1.45e-0537728463250
Pubmed

Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction.

THBS1 THBS2

1.45e-05377212482844
Pubmed

LRRK1 regulation of actin assembly in osteoclasts involves serine 5 phosphorylation of L-plastin.

LRRK1 LCP1

1.45e-05377230136304
Pubmed

Thrombospondin-1, -2 and -5 have differential effects on vascular smooth muscle cell physiology.

THBS1 THBS2

1.45e-05377226168731
Pubmed

Reduced expression of thrombospondins and craniofacial dysmorphism in mice overexpressing Fra1.

THBS1 THBS2

1.45e-05377216598380
Pubmed

Promoter methylation of DAPK1, E-cadherin and thrombospondin-1 in de novo and therapy-related myeloid neoplasms.

THBS1 DAPK1

1.45e-05377220655775
Pubmed

Differential Expression Pattern of THBS1 and THBS2 in Lung Cancer: Clinical Outcome and a Systematic-Analysis of Microarray Databases.

THBS1 THBS2

1.45e-05377227513329
Pubmed

Regulation of VEGF-A, VEGFR-I, thrombospondin-1, -2, and -3 expression in a human pituitary cell line (HP75) by TGFbeta1, bFGF, and EGF.

THBS1 THBS2

1.45e-05377215347840
Pubmed

Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment.

DAPK1 LRRK1

1.45e-05377219712061
Pubmed

Association between single nucleotide polymorphisms in thrombospondins genes and coronary artery disease: A meta-analysis.

THBS1 THBS2

1.45e-05377225976449
Pubmed

The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance.

ATF7IP AIRE

1.45e-05377224464130
Pubmed

The Pathological Significance and Prognostic Roles of Thrombospondin-1, and -2, and 4N1K-peptide in Bladder Cancer.

THBS1 THBS2

1.45e-05377231092423
Pubmed

mRNA Expression of thrombospondin 1, 2 and 3 from proximal to distal in human abdominal aortic aneurysm - preliminary report.

THBS1 THBS2

1.45e-05377234669362
Pubmed

Thrombospondin 1 and thrombospondin 2 are expressed as both homo- and heterotrimers.

THBS1 THBS2

1.45e-0537721459996
Pubmed

Polymorphisms in thrombospondin genes and myocardial infarction: a case-control study and a meta-analysis of available evidence.

THBS1 THBS2

1.45e-05377218178577
Pubmed

Differential expression of thrombospondin 1, 2, and 3 during murine development.

THBS1 THBS2

1.45e-0537728400410
Pubmed

Cocaine Triggers Astrocyte-Mediated Synaptogenesis.

THBS1 THBS2

1.45e-05377233069367
Pubmed

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.

CADM1 DST NCOA7 SMARCAD1 ASCC3

2.08e-0514977525231870
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS12 THBS1 THBS2 ADAMTS20

2.40e-057577420637190
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PPP4R1 THBS1 CADM1 DST ARL13B ADNP2 AIRE SMARCAD1 MLST8 USPL1 GSK3A ADD3

2.46e-051285771235914814
Pubmed

Thrombospondin 2 potentiates notch3/jagged1 signaling.

THBS1 THBS2

2.89e-05477219147503
Pubmed

Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets.

THBS1 THBS2

2.89e-0547726338048
Pubmed

Thrombospondin-1 and thrombospondin-2 mRNA and TSP-1 and TSP-2 protein expression in uterine fibroids and correlation to the genes COL1A1 and COL3A1 and to the collagen cross-link hydroxyproline.

THBS1 THBS2

2.89e-05477218089612
Pubmed

Recognition of the N-terminal modules of thrombospondin-1 and thrombospondin-2 by alpha6beta1 integrin.

THBS1 THBS2

2.89e-05477212909644
Pubmed

Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior.

THBS1 THBS2

2.89e-05477211980922
Pubmed

Expression specificity of the mouse exonuclease 1 (mExo1) gene.

SPTA1 CR2

2.89e-05477210497278
Pubmed

Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity.

THBS1 THBS2

2.89e-05477210900205
Pubmed

Spontaneous bacterial keratitis in CD36 knockout mice.

THBS1 THBS2

2.89e-05477220847111
Pubmed

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.

THBS1 THBS2

4.82e-05577230622267
Pubmed

Central corneal thickness does not correlate with TonoLab-measured IOP in several mouse strains with single transgenic mutations of matricellular proteins.

THBS1 THBS2

4.82e-05577223806329
Pubmed

Rad5 and Its Human Homologs, HLTF and SHPRH, Are Novel Interactors of Mismatch Repair.

HLTF SMARCAD1

4.82e-05577235784486
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

PPP4R1 NEK1 DENND1B AGO3 GSTCD EIF5 SIK2 MLST8 DENND4C ADD3

9.63e-051038771026673895
Pubmed

A ciliopathy complex builds distal appendages to initiate ciliogenesis.

ARL13B KIAA0753

1.34e-04877234241634
Pubmed

Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.

THBS1 THBS2

1.34e-04877224460873
Pubmed

Characterization of mouse thrombospondin 2 sequence and expression during cell growth and development.

THBS1 THBS2

1.72e-0497721371115
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RLF DST KANSL1 ACACA RASA3 MYO19 MRPS23 ADNP2 HLTF SMARCAD1 ASCC3

1.88e-041353771129467282
Pubmed

Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.

THBS1 THBS2 ABCA3

2.13e-045277330389913
Pubmed

Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells.

MLST8 GSK3A

3.15e-041277218851840
Pubmed

Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.

ADAMTS12 ADAMTS20

3.15e-041277225770910
Pubmed

Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication.

SPAG5 KIAA0753

3.71e-041377226297806
Pubmed

A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.

RNF19A ATF7IP

4.33e-041477210976766
Pubmed

Sema3F (Semaphorin 3F) Selectively Drives an Extraembryonic Proangiogenic Program.

THBS1 THBS2

4.33e-041477228729362
Pubmed

Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects.

TPRA1 ACACA CR2

4.51e-046777316806233
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PPP4R1 UBR2 PTPN9 CADM1 CSPG5 ARL13B LMTK2 GSK3A KIAA0753

5.13e-04104977927880917
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

RLF DDX59 DST LCP1 DENND4C SPAG5 KIAA0753

5.72e-0464577725281560
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PPP4R1 DST MYO19 SIK2 HLTF SMARCAD1 SPAG5

5.98e-0465077738777146
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

SPTA1 LCP1

7.23e-041877212119179
Pubmed

Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice.

SPTA1 ADD3

8.96e-042077218723693
Pubmed

Adiponectin enhances mouse fetal fat deposition.

ACACA GSK3A

8.96e-042077222872236
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

NEK1 DST ACACA ATF7IP EIF5 NCOA7 SPAG5 ADD3

1.08e-0393477833916271
Pubmed

Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.

MTHFD2L DAPK1 ELAC1

1.10e-039177322610502
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

DST DENND1B MYO19 EIF5 MRPS23 DAPK1 ASCC3

1.11e-0372377734133714
Pubmed

Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.

ARL13B ADAMTS20

1.19e-032377230814516
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

THBS1 THBS2 TPRA1 CSPG5

1.24e-0321077416537572
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

UBR2 DST ACACA CRYZL1

1.28e-0321277433853758
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

DDX59 KANSL1 EIF5 SIK2 NCOA7 ASCC3 NDRG2

1.37e-0375077711230166
Pubmed

Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development.

ARL13B KIAA0753

1.40e-032577226494787
Pubmed

Differential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways.

NEK1 LRRK1

1.40e-032577224947832
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

DST SIK2 KIAA0753

1.49e-031017739872452
Pubmed

siRNA screening identifies differences in the Fanconi anemia pathway in BALB/c-Trp53+/- with susceptibility versus C57BL/6-Trp53+/- mice with resistance to mammary tumors.

FANCE ACACA

1.52e-032677223435420
Pubmed

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.

KANSL1 EIF5 MRPS23 ADD3

1.60e-0322577425277244
Pubmed

Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.

ACACA SPTA1 EIF5 LCP1

1.62e-0322677431452512
Pubmed

Genomic analysis of mouse retinal development.

FANCE RHPN1 CADM1 DST RASA3 EIF5 ADNP2 MTHFD2L

1.72e-03100677815226823
Pubmed

A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth.

ABCA3 NDRG2

1.76e-032877225912685
Pubmed

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.

CADM1 LDLRAD4

1.76e-032877233953184
Pubmed

Functional proteomics mapping of a human signaling pathway.

RLF CADM1 DST KANSL1 ATF7IP ASCC3

2.01e-0359177615231748
Pubmed

Forkhead box transcription factor FoxC1 preserves corneal transparency by regulating vascular growth.

THBS1 THBS2

2.02e-033077222171010
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS12 ADAMTS20

9.64e-041944250
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND1B DENND4C

1.68e-0325442504
CoexpressionGSE20484_MCSG_VS_CXCL4_MONOCYTE_DERIVED_MACROPHAGE_DN

RLF ABCA3 ATF7IP ARL13B DAPK1 AKAP11

2.40e-05195776M7382
CoexpressionGSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_UP

RLF THBS2 CADM1 USPL1 CR2 ADD3

2.62e-05198776M5299
CoexpressionGSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN

PPP4R1 THBS1 PTPN9 DENND1B RNF19A LCP1

2.77e-05200776M6513
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_1000

THBS1 ABCA3 DENND1B KANSL1 RNF19A BIVM EIF5 HLTF ADAMTS20 NCOA7 LRRK1 ASCC3

1.84e-057747612gudmap_developingKidney_e15.5_cortic collect duct_1000
ToppCellsevere_influenza-B_cell|severe_influenza / disease group, cell group and cell class (v2)

TRABD2A NEIL1 MYO19 ANKAR SIK2 AIRE

9.47e-0812877692b250186d6bb08ce4f2f5cc4fb93928f6b92d3a
ToppCellSepsis-Bac-SEP-Myeloid-cDC1|Bac-SEP / Disease, condition lineage and cell class

CADM1 DST DENND1B CPXM1 NCOA7 NDRG2

1.31e-06200776cd381644fd8b8674a017d267bfbb00f2668294ae
ToppCelldroplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l33|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CADM1 MYO19 SPTA1 SIK2 LMTK2

3.89e-06136775a43b3db1754c619d328a26a2ba6af4756629a723
ToppCelldroplet-Heart-nan-3m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATF7IP LMTK2 MTHFD2L CR2 KIAA0753

7.83e-06157775d85a2f56ae313baa9738e81d2756ce1fe1ba50db
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASA3 SIK2 DAPK1 CR2 KIAA0753

7.83e-06157775c779a53b2c67d566f5d417e753cd17196a6bfd1c
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 SPTA1 EIF5 LMTK2 DAPK1

9.68e-06164775f9a2cc12179d5621c9174ec01d7418a71edd28d1
ToppCell356C-Myeloid-Dendritic-cDC1|356C / Donor, Lineage, Cell class and subclass (all cells)

CADM1 DENND1B LAG3 LRRK1 NDRG2

1.03e-051667750590e404f45afce90e20f93f90a3def83949c66b
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NEK1 DDX59 C9orf50 CR2 DENND4C

1.15e-05170775070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCellBac-SEP-Myeloid-cDC1|Bac-SEP / Disease, Lineage and Cell Type

CADM1 DST DENND1B CPXM1 NDRG2

1.25e-05173775f88269327441858ddb8c49b9dd619b76fd53b1da
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEIL1 CSPG5 LAG3 AIRE PON3

1.25e-0517377560e427f6c7d953cef5f692043670ff0b49cdce72
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

DST AGO3 RNF19A LAG3 SIK2

1.36e-051767753de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

DST KANSL1 AGO3 RNF19A SIK2

1.40e-0517777582fdd6185b368f54f03de389427cbe3071d21a99
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCA3 CADM1 ACACA MTHFD2L ASCC3

1.56e-05181775576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCellCOVID-19-APC-like-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

TRABD2A DENND1B LRRK1 LCP1 LDLRAD4

1.64e-05183775703364836b42aa6ac6c68b42b700ac23c4a1afc7
ToppCellCOVID-19-APC-like|COVID-19 / group, cell type (main and fine annotations)

TRABD2A DENND1B LRRK1 LCP1 LDLRAD4

1.64e-05183775b8f5afaf9ff1b2b1bc60be58654d1b23859dafa9
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CADM1 DST DENND1B CPXM1 NDRG2

1.69e-05184775667846c422cfa27e949a24844a305df859cb6760
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-DC1|bone_marrow / Manually curated celltypes from each tissue

THBS2 CADM1 DST LRRK1 NDRG2

1.69e-05184775ee295f6fa898da53883e1358b17f2c2dd177e9a7
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-conventional_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CADM1 DENND1B LAG3 LCP1 LDLRAD4

1.87e-05188775c39083b8020ae507246959abbb299d78bcd14042
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-conventional_dendritic_cell-DC1_(conventional_dendritic_cell)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CADM1 DENND1B LAG3 LCP1 LDLRAD4

1.87e-051887756e7a678474715f035cc13a0e226a937688f54121
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-conventional_dendritic_cell-DC1_(conventional_dendritic_cell)-DC1_L.1.2.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CADM1 DENND1B LAG3 LCP1 LDLRAD4

1.87e-051887758862ecb87fc9b95eccc527387f2332dcc92cfdc3
ToppCellLV-14._Fibroblast_III|World / Chamber and Cluster_Paper

THBS1 THBS2 RNF19A AASS CFAP161

1.92e-051897753922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THBS1 THBS2 RASA3 ARL13B LRRK1

1.97e-051907750fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCell(3)_MNP-(3)_DC_1|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

CADM1 DENND1B LAG3 NDRG2 LDLRAD4

2.02e-05191775cf0ea54670ed478c3302ccfbee9f6b6706e49fcd
ToppCellcellseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CADM1 DENND1B LAG3 LCP1 LDLRAD4

2.07e-051927753674c81aeee6f055cfa854d9429c1b7f5789d0fc
ToppCell(7)_MNP-(7)_DC_1|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

CADM1 DST DENND1B LAG3 NDRG2

2.17e-051947758dbe0188e2af6f14b3b44e5213fbdd581128082f
ToppCellBAL-Severe-cDC_11|Severe / Compartment, Disease Groups and Clusters

CADM1 DENND1B LAG3 NDRG2 LDLRAD4

2.23e-051957752d31a1c2878c86a49a278b6c7decafabf26c3a5c
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 CPXM1 ASCC3 NDRG2

2.23e-051957755c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellCOVID-19-kidney-Fibroblast-1|kidney / Disease (COVID-19 only), tissue and cell type

ADAMTS12 THBS1 THBS2 DST RASA3

2.46e-051997759503646ff1ad248181146ce767e9d12e882ec3bd
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS12 DDX59 DAPK1 AKAP11

8.11e-051327744152529611eeacf0c547e2a134d5b98c45426b13
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-3|TCGA-Brain / Sample_Type by Project: Shred V9

AGO3 ATF7IP ADAMTS20 TASOR2

8.85e-05135774b128596653a5e3b64ed7f657bbfeda35438e2e48
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

AGO3 ATF7IP ADAMTS20 DAPK1

8.85e-051357743351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

AGO3 ATF7IP ADAMTS20 TASOR2

1.30e-04149774768877bade04ca0321593b8470b5011ad8270431
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ADAMTS12 THBS2 CPXM1 LRRK1

1.66e-04159774cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCellICU-SEP-Myeloid-cDC1|ICU-SEP / Disease, Lineage and Cell Type

CADM1 DST DENND1B NDRG2

1.74e-041617749fb73909fc2ec99f96ca2eed1a053bce89de7d16
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

DST DAPK1 NDRG2 ZNF774

1.74e-04161774347edb0de10850b7d16c40945751033289289c9b
ToppCelldroplet-Limb_Muscle-nan-18m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD13B THBS2 ABCA3 LCP1

1.79e-0416277471d7849108a1b59beff40e46000172c45a2f5439
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSPG5 LAG3 AIRE PON3

2.01e-041677748ec7a98b542b134f48df8fbec351693cc5cfe55c
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-plasma_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSPG5 LAG3 AIRE PON3

2.01e-04167774a9f28c4649ce344ae3ba3a3acb58da9c7efad901
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA3 AIRE DAPK1 CR2

2.01e-041677748b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

ADAMTS12 THBS1 THBS2 CPXM1

2.05e-04168774aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSPG5 LAG3 AIRE PON3

2.10e-04169774e348d9877a1bcad4f33dd7b2ce6cb0049583c4d2
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-cDC1|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM1 DENND1B DAPK1 LRRK1

2.10e-04169774da3485d77bb7876fad4f166f6099e681b27457ae
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSPG5 LAG3 AIRE PON3

2.10e-041697743167ca0c826244280e0e07d1e02656cf5e4e75a5
ToppCell10x3'2.3-week_14-16-Myeloid_DC-DC-DC1|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CADM1 DENND1B NCOA7 NDRG2

2.20e-04171774459e1ac0b89571c39db98c0f578eca8f46caa8e3
ToppCellnormal_Lung-T/NK_cells-Exhausted_Tfh|normal_Lung / Location, Cell class and cell subclass

TRABD2A RNF19A LAG3 LDLRAD4

2.30e-04173774e8ead6c51c41dbd43c717ba9d1a7a0ab39c79330
ToppCellLeuk-UTI-Myeloid-cDC1|Leuk-UTI / Disease, Lineage and Cell Type

CADM1 DST DENND1B NDRG2

2.30e-04173774226bb8d881f32d65c60f5e4c034c6d465f8e7ba5
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSPG5 LAG3 AIRE PON3

2.35e-04174774c92eec5a14ca5269673582dd115ead8516e64c3e
ToppCellASK428-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

CADM1 MRPS23 PON3 ALG11

2.40e-04175774e0979e5795a49b4e5c9b88e7fe6b7bda7a413a6c
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSPG5 LAG3 PON3 ENDOU

2.45e-04176774606704098bfdf8bfef740a3544a372fae1e75969
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSPG5 LAG3 PON3 ENDOU

2.45e-04176774acb9e29773030f6452a069f8f7e53eab68ab7bd3
ToppCellmetastatic_Brain-Myeloid_cells-CD141+_DCs|metastatic_Brain / Location, Cell class and cell subclass

CADM1 DENND1B LCP1 NDRG2

2.45e-04176774b9ba7026dee2272c0b483dc0cfa39f74b75f1634
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NEIL1 ATF7IP ANKAR CR2

2.56e-041787745d41fede13c8e64b6fdaf2155f1eb72bcfc32fdb
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 NEIL1 ADNP2 MTHFD2L

2.61e-04179774b7281160c84dd053a2981c9c76ea6cc6d2592cd5
ToppCellCOPD-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

SIK2 NCOA7 HERC2P3 LDLRAD4

2.61e-04179774e816dd846a6918ec143b57a380c3a47ed073b66e
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEK1 THBS2 ALG11 DENND4C

2.61e-04179774ce3ca7f3a5864e62307aa744a3173f350a90df28
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD8-positive,_alpha-beta_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CADM1 RASA3 RNF19A LAG3

2.61e-04179774c1f7c1b73dc1cb2135da390b16d3b5bd645cd724
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS12 ANKRD13B THBS2 CPXM1

2.67e-04180774935c091bbcd6d10b81dc4731779e5bd98205c99f
ToppCell5'-Airway_Nasal-Mesenchymal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS12 ANKRD13B THBS2 CPXM1

2.67e-041807743dd384b7f3d9582b8fec9fe05100e466e6218b76
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BIVM LRRK1 ELAC1 KIAA0753

2.67e-04180774be10fe5bf7c3a671c42704ce7dd8226ab6896794
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM1 LAG3 EIF5 NDRG2

2.67e-0418077454e3f289a37d4cfbfca4fb284c3b52e9c7d9da97
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BIVM LRRK1 ELAC1 KIAA0753

2.67e-041807743b747a517ce75ef2ff09011c037dad7b01ed3e03
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM1 LAG3 EIF5 NDRG2

2.67e-04180774bfc8568d57034dd9c9e07edae94479a48ca0706d
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NEIL1 SPTA1 AIRE LCP1

2.73e-0418177451e4d6bfdbf414d8e30aee2e6f7492f4f7f54373
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSPG5 LAG3 PON3 ENDOU

2.73e-0418177497022416d0f5a5ba9c9bd5e70ce95cf4cb19af89
ToppCellControl-Myeloid-DC1|Control / Condition, Lineage and Cell class

CADM1 DENND1B LRRK1 NDRG2

2.73e-041817745a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCellwk_20-22-Hematologic-Meg-ery-Definitive_erythroblast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

UBR2 RNF19A SPTA1 EIF5

2.78e-041827740c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THBS1 THBS2 RASA3 LDLRAD4

2.78e-04182774ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-plasma_cell-plasma_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSPG5 LAG3 PON3 ENDOU

2.84e-041837740f6799e4f058bed546fe5759502430f4a19635da
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

CADM1 LAG3 NCOA7 LCP1

2.84e-04183774f593a89b0aa8fffdfa403769916facfd30358521
ToppCelldroplet-Marrow-nan-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM1 LAG3 PON3 NDRG2

2.84e-04183774b5782b18decfe85026acf42daac0670d92385861
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM1 LAG3 PON3 NDRG2

2.84e-04183774e32847cfebba7c8bb2026e33c3c85f64819460a9
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-plasma_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSPG5 LAG3 PON3 ENDOU

2.84e-041837748ef5223e46f1fd81a856261248cc77e7c7e72ef6
ToppCellControl-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

CADM1 DENND1B LAG3 NDRG2

2.90e-04184774c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCA3 CADM1 PON3 DAPK1

2.90e-0418477449705c8fec565b16216bdf48e83e27521f52d99a
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CADM1 DENND1B CPXM1 NDRG2

2.90e-04184774a6f8b42982ec0cf44b950a2cd9715d068eec4ecb
ToppCellControl-CD8+_T_activated|Control / Disease group and Cell class

ARL13B LAG3 MLST8 SPAG5

2.90e-04184774b86cc48b744b3206880ec1373fe6068e14bf9680
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHPN1 CADM1 CSPG5 C9orf50

2.96e-0418577411c147f3f5570c4761d2bcff3bad28146b4a5861
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-conventional_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CADM1 DENND1B LCP1 LDLRAD4

2.96e-04185774209c7d769dd01c349f0a6d147ac9d6225a85160f
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-conventional_dendritic_cell-DC1_(conventional_dendritic_cell)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CADM1 DENND1B LCP1 LDLRAD4

2.96e-041857741f37191eeddaf95e1ad1a206fee86525a2e94e51
ToppCellCF-Myeloid-cDC|CF / Disease state, Lineage and Cell class

TRABD2A DST DENND1B LDLRAD4

2.96e-041857747f3d118845ff9f5f525796b0bbc6532a8ee323ab
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-conventional_dendritic_cell-DC1_(conventional_dendritic_cell)-DC1_L.1.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CADM1 DENND1B LCP1 LDLRAD4

2.96e-0418577470d3f804b43a8843c5af53aefe677fdfc8bb61ff
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THBS1 THBS2 RASA3 LDLRAD4

2.96e-04185774e58a009aaf342be019a909747b1895d5987d4daf
ToppCellCOVID-19_Convalescent-PLT_4|World / Disease Group and Platelet Clusters

RLF ARL13B EIF5 LDLRAD4

3.02e-041867745954a1e3ffafb33f2a9bc87af3343f304fda4c92
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2A RASA3 ATF7IP LCP1

3.02e-041867749d576dce2c5deefef1adda16c6da7055c8d57f8f
ToppCellIPF-Myeloid-cDC1|World / Disease state, Lineage and Cell class

CADM1 DENND1B NDRG2 LDLRAD4

3.02e-04186774962c2dada19185628ead77c32fcb07fa95114247
ToppCell21-Trachea-Epithelial-Goblet-like_secretory|Trachea / Age, Tissue, Lineage and Cell class

LAG3 PON3 NCOA7 NDRG2

3.02e-04186774f8cddad28896f0edf10a8645fa49a011b22b120d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2A RASA3 ATF7IP LCP1

3.02e-04186774bd3bd022b575d9b0ef90d50a5cb874085a827b77
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CADM1 LRRK1 LCP1 LDLRAD4

3.02e-04186774305f1726b8b5add32f1c29c74991ff34f42e0da7
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS12 THBS1 THBS2 DST

3.02e-041867745473283fb95cee556b1f6934cf72169b676b5bcc
ToppCellnormal_Lung-Myeloid_cells-CD141+_DCs|normal_Lung / Location, Cell class and cell subclass

CADM1 DENND1B NDRG2 LDLRAD4

3.02e-04186774a6698a2f4edd81b67e06531ede0e207dd0309205
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2A RASA3 ATF7IP LCP1

3.02e-04186774924cc357b4c4ce8e9b05773bdab544f0b65474cc
ToppCellControl-Myeloid-cDC1|Control / Disease state, Lineage and Cell class

CADM1 DENND1B NDRG2 LDLRAD4

3.02e-04186774b05c394aa3573ba855abc3066739ca193883b0c3
ToppCell367C-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CADM1 DENND1B LAG3 LDLRAD4

3.09e-041877743748203b62abf51b74dfcfc4f18b3ba831b63a96
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPP4R1 DST MTHFD2L DAPK1

3.09e-0418777487b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTS12 THBS1 THBS2 RASA3

3.09e-0418777476bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPP4R1 DST MTHFD2L DAPK1

3.09e-0418777442a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPP4R1 DST MTHFD2L DAPK1

3.09e-0418777464afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

RLF KANSL1 ATF7IP TASOR2

3.15e-04188774ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CADM1 DENND1B NDRG2 LDLRAD4

3.15e-04188774d5ce3ffe783c322b4765b790e861727e46bc34b3
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

ABCA3 ACACA AASS NCOA7

3.15e-04188774ec38def1fdbb34ed9b30244806975bd5a4370164
DrugBerberine chloride [633-65-8]; Down 200; 10.8uM; HL60; HG-U133A

NEK1 DENND1B ACACA AGO3 EIF5 HLTF KIAA0753

3.64e-061927671778_DN
Diseaseamyotrophic lateral sclerosis (is_implicated_in)

NEK1 PON3 GSK3A

7.13e-0532743DOID:332 (is_implicated_in)
Diseaseasphyxiating thoracic dystrophy (is_implicated_in)

NEK1 KIAA0753

1.29e-047742DOID:0050592 (is_implicated_in)
DiseaseDiabetic Angiopathies

THBS1 THBS2

7.28e-0416742C0011875
DiseaseMicroangiopathy, Diabetic

THBS1 THBS2

7.28e-0416742C0025945
DiseaseSjogren's syndrome (implicated_via_orthology)

THBS1 AIRE

8.24e-0417742DOID:12894 (implicated_via_orthology)
Diseasebeta-aminoisobutyric acid measurement

AGXT2 CR2

1.65e-0324742EFO_0010464
Diseaseage at assessment, lateral ventricle volume change measurement

RNF19A LCP1

2.09e-0327742EFO_0008007, EFO_0021502
Diseaserespiratory failure, COVID-19

DST KANSL1

2.41e-0329742EFO_0009686, MONDO_0100096

Protein segments in the cluster

PeptideGeneStartEntry
PLPREEVNQIHEDCK

AGXT2

451

Q9BYV1
PCDVQTFLDIPLHEK

ALG11

281

Q2TAA5
PNIQDKEEETPLHCA

DAPK1

471

P53355
HQLQEKCAEEPEPLT

C9orf50

156

Q5SZB4
ICQDDPSAPHKIQEV

CSPG5

511

O95196
PQNVPEKLEENHELF

ADD3

601

Q9UEY8
CEETVEEPALLHPQS

GSG1

101

Q2KHT4
NELPCEYVEPHELKE

AASS

236

Q9UDR5
ELSCDKFPHENELPQ

CPXM1

591

Q96SM3
TLVKEPHCNPEDISQ

ABCA3

761

Q99758
LELNPRLQVEHPCTE

ACACA

436

Q13085
ECPQHSPLEDIKQRK

BIVM

181

Q86UB2
EEDNECHVTPELPKS

AKAP11

1496

Q9UKA4
NHRVEPLNIDDCAPE

ARL13B

356

Q3SXY8
PDEIQSHLKDELEVP

CFAP161

96

Q6P656
CEVLDIHNIDEQPRP

AGO3

236

Q9H9G7
KPETTNCVPQERELH

CST11

96

Q9H112
TEDQDQCLCDHKPRP

ADAMTS12

1506

P58397
QILEDHNCEIVNKPP

ADAMTS20

1391

P59510
PSDPQLHQKNEDECA

AIRE

286

O43918
HEDEIDQELVIPCPN

ADNP2

96

Q6IQ32
EEICQSHKPCEIDPV

RASA3

401

Q14644
TEENLQLDPPDSHCL

CRYZL1

261

O95825
EVTQHLPRECLPENL

PTPN9

221

P43378
PSLINLLVCDEPEVH

ANKAR

786

Q7Z5J8
EEHPLSLCEQVAPII

ANKRD13B

376

Q86YJ7
QNPDLLELCHSVPKE

NEIL1

221

Q96FI4
QHSKCDVDKSVQPEP

NEK1

971

Q96PY6
EVLCLNDNHLDTVPP

LRRK1

551

Q38SD2
CPHSEEATLEPLIQD

MYO19

696

Q96H55
PEHEETPENRKCAID

DST

2076

Q03001
PIIDFEHCSLPEVLN

DDX59

201

Q5T1V6
DLKTDHNEQLIPEPE

MLST8

156

Q9BVC4
NKALENDPDCRHVIP

LCP1

131

P13796
QPLLLKEETCLDPQH

PGLYRP3

156

Q96LB9
HLCTEDHKESEPLPQ

ENDOU

56

P21128
PLAHSPQAECEDQLD

KANSL1

1041

Q7Z3B3
DVIVPEDCLHQDISP

LMTK2

846

Q8IWU2
HPPQAQSKIEELEQE

LAG3

491

P18627
KEDDGVPVICQVEHP

CADM1

211

Q9BY67
ECENPETDLHVNPKK

EIF5

101

P55010
QEPQSELLEPVCHQL

FAM126A

46

Q9BYI3
CHRDIKPQNLLVDPD

GSK3A

241

P49840
DPEIPVCEKETCQHV

CR2

651

P20023
PQRKQEEEHLEACPA

ERICH4

106

A6NGS2
DLHDPPQDVVCIDLD

DENND4C

476

Q5VZ89
NKQDDDLNCEPLSPH

ATF7IP

101

Q6VMQ6
LEPCDEIEQKIAEPN

FAM102B

251

Q5T8I3
EDAPPVELQLLHECS

FANCE

306

Q9HB96
RNDIHEDNLLECPPE

HLTF

801

Q14527
ACEQVLKDQPALVPH

DENND1B

156

Q6P3S1
EQHPNLCEVPGVEEQ

GSTCD

351

Q8NEC7
DKSILQKCNPHPEDE

PCARE

681

A6NGG8
ETQKEVPQDQHLEAP

MRPS23

166

Q9Y3D9
ETCQHESDEQPLDPI

SPAG5

91

Q96R06
IENLEPHIDDPDVKA

PPP4R1

511

Q8TF05
KEPTHCEANPDLIFE

SMARCAD1

806

Q9H4L7
PHEDAVVECNSKLDP

NDRG2

266

Q9UN36
PHKSDPLVIENGCEE

NCOA7

251

Q8NI08
CKEPPRSLEQQLQEH

SIK2

701

Q9H0K1
LEEACILPHSPINVD

HERC2P3

306

Q9BVR0
KEPLQQEDPQEESHL

KIAA0753

586

Q2KHM9
CEAAEAPDIQPKTHQ

RHPN1

461

Q8TCX5
NEHLQEACTPELKPV

ASCC3

201

Q8N3C0
CQVDETEEPDVHLPQ

TPRA1

296

Q86W33
HDSVPDIDDICPENV

THBS1

936

P07996
LNNLISPDLEECHTP

USPL1

86

Q5W0Q7
HNQTTEKLDAEPKPC

RLF

1001

Q13129
PEVENDRLENSPHQC

RNF19A

761

Q9NV58
LENPLQECHPAQLEE

ZNF774

16

Q6NX45
VEKVEEQCHPLNGLN

TRABD2A

206

Q86V40
SREVEPVEPENCHLI

PON3

31

Q15166
PVEPENCHLIEELES

PON3

36

Q15166
HELVPTADQCPAEEL

ELAC1

121

Q9H777
ANECAEENHPDLPLI

SPTA1

221

P02549
LQAAEHPDEVEDPKN

SMAP

151

O00193
QLPLPDHVDERTICN

MTHFD2L

146

Q9H903
PINNECHPSLERKDD

TASOR2

1026

Q5VWN6
DNCPLVHNPDQTDVD

THBS2

836

P35442
LVPNDSHEELPCILD

UBR2

1396

Q8IWV8
NSDEENCLLVTEHPP

LDLRAD4

41

O15165