Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cysteine-type deubiquitinase activity	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	1.27e-24	114	77	18	GO:0004843
GeneOntologyMolecularFunction	deubiquitinase activity	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	6.31e-24	124	77	18	GO:0101005
GeneOntologyMolecularFunction	ubiquitin-like protein peptidase activity	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	4.16e-23	137	77	18	GO:0019783
GeneOntologyMolecularFunction	cysteine-type peptidase activity	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 CASP6 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	5.99e-22	192	77	19	GO:0008234
GeneOntologyMolecularFunction	peptidase activity	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 CASP6 USP17L5 USP17L10 REN USP17L19 NCSTN USP17L22 USP17L15 USP17L13 USP17L18	3.45e-14	654	77	21	GO:0008233
GeneOntologyMolecularFunction	protein methyltransferase activity	KMT2B SUV39H1 FBXO11 FAM98A	6.77e-04	103	77	4	GO:0008276
GeneOntologyMolecularFunction	structural constituent of postsynaptic density	DLG1 DLG4	7.89e-04	11	77	2	GO:0098919
GeneOntologyMolecularFunction	structural constituent of postsynaptic specialization	DLG1 DLG4	1.11e-03	13	77	2	GO:0098879
GeneOntologyMolecularFunction	fucosyltransferase activity	FUT9 FUT8	1.30e-03	14	77	2	GO:0008417
GeneOntologyMolecularFunction	methyltransferase activity	ALKBH8 KMT2B SUV39H1 FBXO11 FAM98A	1.40e-03	213	77	5	GO:0008168
GeneOntologyMolecularFunction	transferase activity, transferring one-carbon groups	ALKBH8 KMT2B SUV39H1 FBXO11 FAM98A	1.74e-03	224	77	5	GO:0016741
GeneOntologyBiologicalProcess	protein deubiquitination	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	2.44e-24	125	75	18	GO:0016579
GeneOntologyBiologicalProcess	protein modification by small protein removal	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	3.54e-23	144	75	18	GO:0070646
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 SAE1 USP17L5 FBXO11 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	3.17e-10	1009	75	20	GO:0070647
GeneOntologyBiologicalProcess	post-translational protein modification	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 SAE1 USP17L5 FBXO11 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	9.40e-10	1074	75	20	GO:0043687
GeneOntologyBiologicalProcess	N-glycan fucosylation	FUT9 FUT8	1.30e-04	5	75	2	GO:0036071
GeneOntologyCellularComponent	endoplasmic reticulum membrane	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 PDIA5 DLG1 TMTC2 USP17L10 USP17L19 NCSTN TMEM151A USP17L22 USP17L15 USP17L13 USP17L18	1.83e-09	1293	80	22	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 PDIA5 DLG1 TMTC2 USP17L10 USP17L19 NCSTN TMEM151A USP17L22 USP17L15 USP17L13 USP17L18	1.99e-09	1299	80	22	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 PDIA5 DLG1 TMTC2 USP17L10 USP17L19 NCSTN TMEM151A USP17L22 USP17L15 USP17L13 USP17L18	2.96e-09	1327	80	22	GO:0042175
MousePheno	increased trophectoderm apoptosis	USP17L2 USP17L15 USP17L13	1.85e-06	8	46	3	MP:0012119
MousePheno	increased thymus weight	USP17L2 USP17L15 USP17L13	6.43e-05	24	46	3	MP:0004955
Domain	HABP4_PAI-RBP1	USP17L7 USP17L21 USP17L2 USP17L12 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L19 USP17L22 USP17L13 USP17L18	1.14e-32	16	76	14	PF04774
Domain	HABP4_PAIRBP1-bd	USP17L7 USP17L21 USP17L2 USP17L12 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L19 USP17L22 USP17L13 USP17L18	1.14e-32	16	76	14	IPR006861
Domain	USP_CS	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L13 USP17L18	7.65e-25	66	76	16	IPR018200
Domain	UCH	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L13 USP17L18	2.82e-24	71	76	16	PF00443
Domain	USP_2	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L13 USP17L18	2.82e-24	71	76	16	PS00973
Domain	USP_3	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L13 USP17L18	3.61e-24	72	76	16	PS50235
Domain	USP_dom	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L13 USP17L18	3.61e-24	72	76	16	IPR028889
Domain	Peptidase_C19_UCH	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L13 USP17L18	3.61e-24	72	76	16	IPR001394
Domain	USP_1	USP17L7 USP17L21 USP17L2 USP17L12 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L13 USP17L18	1.94e-22	70	76	15	PS00972
Domain	MAGUK_N_PEST	DLG1 DLG4	9.75e-05	4	76	2	PF10608
Domain	PDZ_assoc	DLG1 DLG4	9.75e-05	4	76	2	PF10600
Domain	DLG1_PEST_dom	DLG1 DLG4	9.75e-05	4	76	2	IPR019590
Domain	PDZ_assoc	DLG1 DLG4	9.75e-05	4	76	2	IPR019583
Domain	MAGUK_N_PEST	DLG1 DLG4	9.75e-05	4	76	2	SM01277
Domain	DLG1	DLG1 DLG4	9.75e-05	4	76	2	IPR016313
Domain	DUF4704	NBEAL1 NBEAL2	1.62e-04	5	76	2	IPR031570
Domain	DUF4704	NBEAL1 NBEAL2	1.62e-04	5	76	2	PF15787
Domain	PH_BEACH	NBEAL1 NBEAL2	2.43e-04	6	76	2	PF14844
Domain	PH-BEACH_dom	NBEAL1 NBEAL2	4.50e-04	8	76	2	IPR023362
Domain	-	NBEAL1 NBEAL2	4.50e-04	8	76	2	2.30.29.40
Domain	PH_BEACH	NBEAL1 NBEAL2	4.50e-04	8	76	2	PS51783
Domain	SH3_1	ARHGAP10 DLG1 DLG4 NEB FUT8	5.49e-04	164	76	5	PF00018
Domain	BEACH_dom	NBEAL1 NBEAL2	5.77e-04	9	76	2	IPR000409
Domain	BEACH	NBEAL1 NBEAL2	5.77e-04	9	76	2	PS50197
Domain	Beach	NBEAL1 NBEAL2	5.77e-04	9	76	2	PF02138
Domain	-	NBEAL1 NBEAL2	5.77e-04	9	76	2	1.10.1540.10
Domain	Beach	NBEAL1 NBEAL2	5.77e-04	9	76	2	SM01026
Domain	TIL	MUC5AC MUC6	1.05e-03	12	76	2	PF01826
Domain	C8	MUC5AC MUC6	1.05e-03	12	76	2	PF08742
Domain	Unchr_dom_Cys-rich	MUC5AC MUC6	1.24e-03	13	76	2	IPR014853
Domain	C8	MUC5AC MUC6	1.24e-03	13	76	2	SM00832
Domain	TIL_dom	MUC5AC MUC6	1.44e-03	14	76	2	IPR002919
Domain	SH3	ARHGAP10 DLG1 DLG4 NEB FUT8	1.88e-03	216	76	5	SM00326
Domain	SH3	ARHGAP10 DLG1 DLG4 NEB FUT8	1.88e-03	216	76	5	PS50002
Domain	Post-SET_dom	KMT2B SUV39H1	1.89e-03	16	76	2	IPR003616
Domain	VWD	MUC5AC MUC6	1.89e-03	16	76	2	SM00216
Domain	PostSET	KMT2B SUV39H1	1.89e-03	16	76	2	SM00508
Domain	Guanylate_kinase_CS	DLG1 DLG4	1.89e-03	16	76	2	IPR020590
Domain	VWF_type-D	MUC5AC MUC6	1.89e-03	16	76	2	IPR001846
Domain	VWFD	MUC5AC MUC6	1.89e-03	16	76	2	PS51233
Domain	POST_SET	KMT2B SUV39H1	1.89e-03	16	76	2	PS50868
Domain	VWD	MUC5AC MUC6	1.89e-03	16	76	2	PF00094
Domain	SH3_domain	ARHGAP10 DLG1 DLG4 NEB FUT8	2.03e-03	220	76	5	IPR001452
Domain	-	WDHD1 NBEAL1 NBEAL2 WDR1 WDR13 PLXNB3	2.36e-03	333	76	6	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	WDHD1 NBEAL1 NBEAL2 WDR1 WDR13 PLXNB3	2.43e-03	335	76	6	IPR015943
Domain	VWC_out	MUC5AC MUC6	2.67e-03	19	76	2	SM00215
Domain	CT	MUC5AC MUC6	3.58e-03	22	76	2	SM00041
Domain	GUANYLATE_KINASE_2	DLG1 DLG4	3.91e-03	23	76	2	PS50052
Domain	GUANYLATE_KINASE_1	DLG1 DLG4	3.91e-03	23	76	2	PS00856
Domain	SH3_9	ARHGAP10 NEB FUT8	3.96e-03	78	76	3	PF14604
Domain	WD40	WDHD1 NBEAL1 NBEAL2 WDR1 WDR13	4.09e-03	259	76	5	PF00400
Domain	Cys_knot_C	MUC5AC MUC6	4.61e-03	25	76	2	IPR006207
Domain	CTCK_2	MUC5AC MUC6	4.61e-03	25	76	2	PS01225
Domain	WD40	WDHD1 NBEAL1 NBEAL2 WDR1 WDR13	4.73e-03	268	76	5	SM00320
Domain	Guanylate_kin	DLG1 DLG4	4.99e-03	26	76	2	PF00625
Domain	GK/Ca_channel_bsu	DLG1 DLG4	4.99e-03	26	76	2	IPR008145
Domain	Guanylate_kin-like_dom	DLG1 DLG4	4.99e-03	26	76	2	IPR008144
Domain	GuKc	DLG1 DLG4	4.99e-03	26	76	2	SM00072
Domain	WD40_repeat	WDHD1 NBEAL1 NBEAL2 WDR1 WDR13	5.03e-03	272	76	5	IPR001680
Domain	WD_REPEATS_1	WDHD1 NBEAL1 NBEAL2 WDR1 WDR13	5.51e-03	278	76	5	PS00678
Domain	WD_REPEATS_2	WDHD1 NBEAL1 NBEAL2 WDR1 WDR13	5.59e-03	279	76	5	PS50082
Domain	WD_REPEATS_REGION	WDHD1 NBEAL1 NBEAL2 WDR1 WDR13	5.59e-03	279	76	5	PS50294
Domain	Calcineurin-like_PHP_ApaH	SMPDL3A MPPE1	5.77e-03	28	76	2	IPR004843
Domain	Metallophos	SMPDL3A MPPE1	5.77e-03	28	76	2	PF00149
Domain	Metallo-depent_PP-like	SMPDL3A MPPE1	6.60e-03	30	76	2	IPR029052
Domain	-	SMPDL3A MPPE1	6.60e-03	30	76	2	3.60.21.10
Domain	WD40_repeat_dom	WDHD1 NBEAL1 NBEAL2 WDR1 WDR13	7.24e-03	297	76	5	IPR017986
Pathway	REACTOME_RAS_PROCESSING	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	1.46e-29	45	64	17	MM15671
Pathway	REACTOME_MAPK_FAMILY_SIGNALING_CASCADES	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 DLG1 DLG4 USP17L10 USP17L19 USP17L22 KIT USP17L15 USP17L13 USP17L18	5.13e-18	318	64	20	MM15278
Pathway	REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	6.73e-18	191	64	17	MM15289
Pathway	REACTOME_DEUBIQUITINATION	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	1.42e-15	262	64	17	MM15286
Pathway	REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES	USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	1.94e-15	221	64	16	M27578
Pathway	REACTOME_DEUBIQUITINATION	USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	2.20e-13	299	64	16	M27574
Pathway	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 ART4 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 SAE1 USP17L5 FBXO11 USP17L10 USP17L19 FUT8 USP17L22 MUC5AC MUC6 ARSI USP17L15 USP17L13 USP17L18	2.97e-09	1389	64	24	MM15307
Pathway	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	USP17L21 USP17L2 USP17L12 USP17L1 ART4 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 SAE1 USP17L5 FBXO11 USP17L10 USP17L19 FUT8 USP17L22 MUC5AC MUC6 ARSI USP17L15 USP17L13 USP17L18	5.05e-08	1475	64	23	M19806
Pathway	REACTOME_NRCAM_INTERACTIONS	DLG1 DLG4	4.20e-04	7	64	2	M27378
Pathway	REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS	DLG1 DLG4	8.92e-04	10	64	2	M10272
Pubmed	DUB-1, a deubiquitinating enzyme with growth-suppressing activity.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	1.35e-42	21	80	17	8622927
Pubmed	DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	1.35e-42	21	80	17	14583620
Pubmed	DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	1.35e-42	21	80	17	11468161
Pubmed	The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	1.35e-42	21	80	17	8756639
Pubmed	Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	1.35e-42	21	80	17	12447969
Pubmed	DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	1.35e-42	21	80	17	18980247
Pubmed	JAK2 is required for induction of the murine DUB-1 gene.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	5.94e-42	22	80	17	9154835
Pubmed	DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	7.78e-41	24	80	17	8995226
Pubmed	Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	2.43e-40	25	80	17	21115691
Pubmed	Cdc25A and Dub3 in a high-stakes balancing act.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	4.17e-40	33	80	18	20228807
Pubmed	Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	7.00e-40	26	80	17	35816173
Pubmed	The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	8.84e-40	34	80	18	20403174
Pubmed	Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	8.84e-40	34	80	18	17109758
Pubmed	The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	8.84e-40	34	80	18	20388806
Pubmed	DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	8.84e-40	34	80	18	14699124
Pubmed	Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	8.84e-40	34	80	18	20715989
Pubmed	Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	8.84e-40	34	80	18	9806828
Pubmed	The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	8.84e-40	34	80	18	20368735
Pubmed	The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	8.84e-40	34	80	18	15780755
Pubmed	USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	8.84e-40	34	80	18	19188362
Pubmed	Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	8.84e-40	34	80	18	11941478
Pubmed	The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	8.84e-40	34	80	18	10936051
Pubmed	The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	8.84e-40	34	80	18	21448158
Pubmed	Cytokine-regulated protein degradation by the ubiquitination system.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	1.82e-39	35	80	18	16611142
Pubmed	Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	1.82e-39	35	80	18	21239494
Pubmed	The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	3.63e-39	36	80	18	20147298
Pubmed	Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	7.05e-39	37	80	18	20228808
Pubmed	Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	1.16e-38	29	80	17	32527007
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	2.12e-33	50	80	17	31806660
Pubmed	USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 ETV1 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 LGALS7 USP17L13 USP17L18	8.64e-16	674	80	19	37196079
Pubmed	High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency.	USP17L7 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15	2.55e-14	10	80	6	24207026
Pubmed	Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells.	USP17L7 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15	1.12e-13	12	80	6	24695638
Pubmed	ES cell neural differentiation reveals a substantial number of novel ESTs.	USP17L7 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15	3.62e-13	14	80	6	11793228
Pubmed	CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.	USP17L7 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15	3.24e-12	19	80	6	28067227
Pubmed	A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.	USP17L21 USP17L12 USP17L17 USP17L20 USP17L11 USP17L19 USP17L18	1.19e-08	119	80	7	28625976
Pubmed	Human and mouse proteases: a comparative genomic approach.	USP17L7 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15	3.46e-08	81	80	6	12838346
Pubmed	Embryonic demise caused by targeted disruption of a cysteine protease Dub-2.	USP17L2 USP17L15 USP17L13	4.68e-08	4	80	3	22984479
Pubmed	ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours.	ETV1 KIT	5.23e-06	2	80	2	20927104
Pubmed	Clinicopathological features of superficial non-ampurally duodenal epithelial tumor; gastric phenotype of histology correlates to higher malignant potency.	MUC5AC MUC6	5.23e-06	2	80	2	28321513
Pubmed	Human mucin genes MUC2, MUC3, MUC4, MUC5AC, MUC5B, and MUC6 express stable and extremely large mRNAs and exhibit a variable length polymorphism. An improved method to analyze large mRNAs.	MUC5AC MUC6	5.23e-06	2	80	2	9422745
Pubmed	Expression of Kit and Etv1 in restricted brain regions supports a brain-cell progenitor as an origin for cranial germinomas.	ETV1 KIT	5.23e-06	2	80	2	25736805
Pubmed	Aberrant expression of MUC5AC and MUC6 gastric mucins and sialyl Tn antigen in intraepithelial neoplasms of the pancreas.	MUC5AC MUC6	5.23e-06	2	80	2	12360467
Pubmed	Expression of CD133 and CD117 in 64 Serous Ovarian Cancer Cases.	PROM1 KIT	5.23e-06	2	80	2	26898076
Pubmed	Interaction between SAP97 and PSD-95, two Maguk proteins involved in synaptic trafficking of AMPA receptors.	DLG1 DLG4	5.23e-06	2	80	2	16332687
Pubmed	Gastric MUC5AC and MUC6 are large oligomeric mucins that differ in size, glycosylation and tissue distribution.	MUC5AC MUC6	5.23e-06	2	80	2	11988092
Pubmed	Clustering and enhanced activity of an inwardly rectifying potassium channel, Kir4.1, by an anchoring protein, PSD-95/SAP90.	DLG1 DLG4	1.57e-05	3	80	2	9148889
Pubmed	Mucin expression in reactive gastropathy: an immunohistochemical analysis.	MUC5AC MUC6	1.57e-05	3	80	2	17227128
Pubmed	The cytoplasmic domain of NrCAM binds to PDZ domains of synapse-associated proteins SAP90/PSD95 and SAP97.	DLG1 DLG4	1.57e-05	3	80	2	16882004
Pubmed	Combined inhibition of MAP kinase and KIT signaling synergistically destabilizes ETV1 and suppresses GIST tumor growth.	ETV1 KIT	1.57e-05	3	80	2	25572173
Pubmed	Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex.	DLG1 DLG4	1.57e-05	3	80	2	10939335
Pubmed	Mucin phenotype expression of gastric neuroendocrine neoplasms: analysis of histopathology and carcinogenesis.	MUC5AC MUC6	1.57e-05	3	80	2	23828549
Pubmed	The utility of CD44, CD117 and CD133 in identification of cancer stem cells (CSC) in oral squamous cell carcinomas (OSCC).	PROM1 KIT	1.57e-05	3	80	2	22119814
Pubmed	Overexpression of angiopoietin-1 increases CD133+/c-kit+ cells and reduces myocardial apoptosis in db/db mouse infarcted hearts.	PROM1 KIT	1.57e-05	3	80	2	22558265
Pubmed	Cadherin-catenin adhesion system and mucin expression: a comparison between young and older patients with gastric carcinoma.	MUC5AC MUC6	1.57e-05	3	80	2	18825309
Pubmed	GAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytes.	DLG1 DLG4	1.57e-05	3	80	2	10859302
Pubmed	A specific N-terminal residue in Kv1.5 is required for upregulation of the channel by SAP97.	DLG1 DLG4	1.57e-05	3	80	2	16466689
Pubmed	The receptor protein tyrosine phosphatase, PTP-RO, is upregulated during megakaryocyte differentiation and Is associated with the c-Kit receptor.	PTPRU KIT	1.57e-05	3	80	2	10397721
Pubmed	Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia.	MUC5AC MUC6	1.57e-05	3	80	2	18300795
Pubmed	A comprehensive analysis of common genetic variation in MUC1, MUC5AC, MUC6 genes and risk of stomach cancer.	MUC5AC MUC6	1.57e-05	3	80	2	19924550
Pubmed	Mir-152 inhibits cell proliferation and colony formation of CD133(+) liver cancer stem cells by targeting KIT.	PROM1 KIT	1.57e-05	3	80	2	25311946
Pubmed	The cancer stem cell antigens CD133, BCRP1/ABCG2 and CD117/c-KIT are not associated with prognosis in resected early-stage non-small cell lung cancer.	PROM1 KIT	1.57e-05	3	80	2	22199321
Pubmed	Differential interaction of the tSXV motifs of the NR1 and NR2A NMDA receptor subunits with PSD-95 and SAP97.	DLG1 DLG4	1.57e-05	3	80	2	10336672
Pubmed	Molecular portraits of heterogeneity related to cancer stem cells in human ovarian cancer.	PROM1 KIT	1.57e-05	3	80	2	24300467
Pubmed	Intramolecular interactions regulate SAP97 binding to GKAP.	DLG1 DLG4	1.57e-05	3	80	2	11060025
Pubmed	BEGAIN (brain-enriched guanylate kinase-associated protein), a novel neuronal PSD-95/SAP90-binding protein.	DLG1 DLG4	1.57e-05	3	80	2	9756850
Pubmed	Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1.	ETV1 KIT	1.57e-05	3	80	2	25865047
Pubmed	An inhibitor of the acetyltransferases CBP/p300 exerts antineoplastic effects on gastrointestinal stromal tumor cells.	ETV1 KIT	3.13e-05	4	80	2	27633918
Pubmed	Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein.	DLG1 DLG4	3.13e-05	4	80	2	9326658
Pubmed	Molecular mechanisms regulating the differential association of kainate receptor subunits with SAP90/PSD-95 and SAP97.	DLG1 DLG4	3.13e-05	4	80	2	11279111
Pubmed	Associations between the expression of mucins (MUC1, MUC2, MUC5AC and MUC6) and clinicopathologic parameters of human breast carcinomas.	MUC5AC MUC6	3.13e-05	4	80	2	33154304
Pubmed	Gastric mucin expression in first-degree relatives of gastric cancer patients.	MUC5AC MUC6	3.13e-05	4	80	2	24901817
Pubmed	Lano, a novel LAP protein directly connected to MAGUK proteins in epithelial cells.	DLG1 DLG4	3.13e-05	4	80	2	11440998
Pubmed	Evaluation of MUC1, MUC2, MUC5AC, and MUC6 Expression Differences in Lung Adenocarcinoma Subtypes by Using a Final Immunoreactivity Score (FIRS).	MUC5AC MUC6	3.13e-05	4	80	2	36367122
Pubmed	Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.	MUC5AC MUC6	3.13e-05	4	80	2	17471237
Pubmed	The mouse secreted gel-forming mucin gene cluster.	MUC5AC MUC6	3.13e-05	4	80	2	14984930
Pubmed	Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.	MUC5AC MUC6	3.13e-05	4	80	2	29869461
Pubmed	Mucins in neoplastic spectrum of colorectal polyps: can they provide predictions?	MUC5AC MUC6	3.13e-05	4	80	2	20929551
Pubmed	Ggamma13 interacts with PDZ domain-containing proteins.	DLG1 DLG4	3.13e-05	4	80	2	16473877
Pubmed	Muscarinic-induced recruitment of plasma membrane Ca2+-ATPase involves PSD-95/Dlg/Zo-1-mediated interactions.	DLG1 DLG4	3.13e-05	4	80	2	19017653
Pubmed	Cypin: a cytosolic regulator of PSD-95 postsynaptic targeting.	DLG1 DLG4	3.13e-05	4	80	2	10595517
Pubmed	GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules.	DLG1 DLG4	3.13e-05	4	80	2	9024696
Pubmed	Prognostic significance of CDX2 and mucin expression in small intestinal adenocarcinoma.	MUC5AC MUC6	3.13e-05	4	80	2	24603585
Pubmed	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.	MUC5AC MUC6	3.13e-05	4	80	2	23807779
Pubmed	Expression pattern of membrane-associated guanylate kinases in interneurons of the visual cortex.	DLG1 DLG4	3.13e-05	4	80	2	21031555
Pubmed	A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis.	DLG1 DLG4	3.13e-05	4	80	2	15657400
Pubmed	Synaptic scaffold evolution generated components of vertebrate cognitive complexity.	DLG1 DLG4	3.13e-05	4	80	2	23201973
Pubmed	MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance.	MUC5AC MUC6	3.13e-05	4	80	2	27298226
Pubmed	Association of the kinesin superfamily motor protein KIF1Balpha with postsynaptic density-95 (PSD-95), synapse-associated protein-97, and synaptic scaffolding molecule PSD-95/discs large/zona occludens-1 proteins.	DLG1 DLG4	3.13e-05	4	80	2	12097473
Pubmed	Postsynaptic targeting of alternative postsynaptic density-95 isoforms by distinct mechanisms.	DLG1 DLG4	3.13e-05	4	80	2	12151521
Pubmed	Mucin expression profile in Barrett's, dysplasia, adenocarcinoma sequence in the esophagus.	MUC5AC MUC6	3.13e-05	4	80	2	17401217
Pubmed	Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.	MUC5AC MUC6	3.13e-05	4	80	2	12676567
Pubmed	Expression profile of mucins (MUC1, MUC2, MUC5AC, and MUC6) in ovarian mucinous tumours: changes in expression from benign to malignant tumours.	MUC5AC MUC6	3.13e-05	4	80	2	25298197
Pubmed	Sema4c, a transmembrane semaphorin, interacts with a post-synaptic density protein, PSD-95.	DLG1 DLG4	5.20e-05	5	80	2	11134026
Pubmed	Localization of postsynaptic density-93 to dendritic microtubules and interaction with microtubule-associated protein 1A.	DLG1 DLG4	5.20e-05	5	80	2	9786987
Pubmed	Selective interaction of megalin with postsynaptic density-95 (PSD-95)-like membrane-associated guanylate kinase (MAGUK) proteins.	DLG1 DLG4	5.20e-05	5	80	2	12713445
Pubmed	Glutamatergic neurons induce expression of functional glutamatergic synapses in primary myotubes.	DLG1 DLG4	5.20e-05	5	80	2	22347480
Pubmed	SAP97 increases Kv1.5 currents through an indirect N-terminal mechanism.	DLG1 DLG4	5.20e-05	5	80	2	12860415
Pubmed	Divergent expression of MUC5AC, MUC6, MUC2, CD10, and CDX-2 in dysplasia and intramucosal adenocarcinomas with intestinal and foveolar morphology: is this evidence of distinct gastric and intestinal pathways to carcinogenesis in Barrett Esophagus?	MUC5AC MUC6	5.20e-05	5	80	2	22261707
Pubmed	Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases.	DLG1 DLG4	5.20e-05	5	80	2	8601796
Pubmed	SAP90 binds and clusters kainate receptors causing incomplete desensitization.	DLG1 DLG4	5.20e-05	5	80	2	9808460
Cytoband	4p16.1	USP17L21 USP17L12 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L5 USP17L10 USP17L19 WDR1 USP17L22 USP17L15 USP17L13 USP17L18	5.08e-27	79	80	15	4p16.1
Cytoband	Ensembl 112 genes in cytogenetic band chr4p16	USP17L21 USP17L12 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L5 USP17L10 USP17L19 WDR1 USP17L22 USP17L15 USP17L13 USP17L18	5.76e-20	222	80	15	chr4p16
Cytoband	8p23.1	USP17L7 USP17L2 USP17L1 USP17L3	1.58e-04	154	80	4	8p23.1
Cytoband	Ensembl 112 genes in cytogenetic band chr8p23	USP17L7 USP17L2 USP17L1 USP17L3	7.68e-04	234	80	4	chr8p23
Cytoband	Ensembl 112 genes in cytogenetic band chr14q23	PLEKHG3 FUT8 PPM1A	1.55e-03	130	80	3	chr14q23
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 NBEAL2	2.56e-04	9	49	2	1230
GeneFamily	Fucosyltransferases\|Blood group antigens	FUT9 FUT8	5.51e-04	13	49	2	434
GeneFamily	WD repeat domain containing	WDHD1 NBEAL1 NBEAL2 WDR1 WDR13	6.97e-04	262	49	5	362
GeneFamily	CD molecules\|Mucins	MUC5AC MUC6	1.46e-03	21	49	2	648
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	DLG1 DLG4	2.24e-03	26	49	2	904
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2B SUV39H1	3.82e-03	34	49	2	487
Coexpression	MADAN_DPPA4_TARGETS	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	7.49e-27	86	79	17	MM1312
Coexpression	GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 CASP6 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	1.20e-26	112	79	18	MM1095
Coexpression	GERY_CEBP_TARGETS	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	5.48e-22	160	79	17	MM1155
Coexpression	GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 NBEAL2 ANKRD10 USP17L6P USP17L3 USP17L5 USP17L10 REN USP17L19 USP17L22 USP17L15 PPM1A USP17L13 USP17L18	2.47e-16	647	79	21	MM981
Coexpression	GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 NBEAL2 ANKRD10 USP17L6P USP17L3 USP17L5 USP17L10 REN USP17L19 USP17L22 USP17L15 PPM1A USP17L13 USP17L18	5.52e-11	1226	79	21	MM979
Coexpression	MARSON_BOUND_BY_FOXP3_STIMULATED	USP17L7 USP17L21 SYNRG USP17L2 USP17L12 USP17L1 USP17L17 ARHGAP10 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	3.09e-10	1072	79	19	MM1031
Coexpression	BRUINS_UVC_RESPONSE_LATE	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 CLPB USP17L17 USP17L20 USP17L11 USP17L6P USP17L3 USP17L5 PDIA5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	1.95e-09	1198	79	19	MM1062
Drug	Hesperidin [520-26-3]; Up 200; 6.6uM; HL60; HT_HG-U133A	SMPDL3A C2orf42 DLG1 FBXO11 WDR1 NEB MAP3K2	1.34e-06	194	65	7	1294_UP
Disease	primary ovarian insufficiency (implicated_via_orthology)	USP17L7 USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	9.78e-36	46	77	18	DOID:5426 (implicated_via_orthology)
Disease	congenital heart disease (implicated_via_orthology)	USP17L7 USP17L21 USP17L2 KMT2B USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L6P USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	3.08e-34	69	77	19	DOID:1682 (implicated_via_orthology)
Disease	mucinous adenocarcinoma (is_marker_for)	MUC5AC MUC6	6.69e-05	5	77	2	DOID:3030 (is_marker_for)
Disease	benign neoplasm (implicated_via_orthology)	DLG1 DLG4	1.86e-04	8	77	2	DOID:0060072 (implicated_via_orthology)
Disease	renin measurement	NBEAL1 REN	1.86e-04	8	77	2	EFO_0010616
Disease	developmental disorder of mental health (implicated_via_orthology)	DLG1 DLG4 PLXNB3	2.89e-04	49	77	3	DOID:0060037 (implicated_via_orthology)
Disease	gastric ulcer (implicated_via_orthology)	MUC5AC MUC6	5.99e-04	14	77	2	DOID:10808 (implicated_via_orthology)
Disease	dystonia (is_implicated_in)	KMT2B TMEM151A	5.99e-04	14	77	2	DOID:543 (is_implicated_in)
Disease	cholangiocarcinoma (is_marker_for)	KIT MUC5AC MUC6	6.35e-04	64	77	3	DOID:4947 (is_marker_for)
Disease	carcinoma (implicated_via_orthology)	DLG1 DLG4 KIT	6.35e-04	64	77	3	DOID:305 (implicated_via_orthology)
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	KMT2B DLG4	8.91e-04	17	77	2	DOID:0060307 (is_implicated_in)
Disease	PR interval	MYO3A ARHGEF40 DLG1 ASTN2 FBXO11 SIPA1L2	1.88e-03	495	77	6	EFO_0004462

Protein segments in the cluster

Peptide	Gene	Start	Entry
YGHHRNGHVAEYQDQ	C2orf42	541	Q9NWW7
RHGDQFSLYAQYVKH	ARHGEF40	1161	Q8TER5
EDIGDNLYYGHYHGF	ANKRD10	366	Q9NXR5
HTDGHGYKYFSGKNV	CXorf58	121	Q96LI9
VKHFGYEFHYENNNV	ALKBH8	176	Q96BT7
FILTDDQGYHDVGYH	ARSI	51	Q5FYB1
HKFIEAGQYNNHLYG	DLG1	776	Q12959
LGDYMSFHFEHYQDN	RTL10	121	Q7L3V2
AGYFQKVAEYVHGAG	ETNPPL	226	Q8TBG4
VQHHYNSHYEKFGDF	ASTN2	1236	O75129
QYEAHTFYDGHENMA	NBEAL1	1696	Q6ZS30
DKFHYGTHYSNSAGV	NBEAL1	2091	Q6ZS30
LADHSGAFHNKYYQS	NCSTN	441	Q92542
GHGHFKLQKTYENNY	PCDH18	401	Q9HCL0
DGFKAVVGDAQYHHF	LGALS7	96	P47929
HYKENQYFHVHGGIE	ANKAR	371	Q7Z5J8
YHQGHELAKDFNHYK	ARHGAP10	211	A1A4S6
CGFYNTHTQDGHGEY	MUC6	1131	Q6W4X9
EAEYSDKHGQYLIGH	EPHB4	571	P54760
QEKYNSWHHGDFNYE	KIT	256	P10721
KYSDVIAGQFYGHTH	SMPDL3A	281	Q92484
HTYGQAFGEYVNDKN	FUT9	216	Q9Y231
HGEGNHIYAYDAKIE	CASP6	121	P55212
GNHDIGFHYEMNTYK	MPPE1	156	Q53F39
YKVFLHGSQGQVYHS	PLXNB3	421	Q9ULL4
GFKQEYHDPVYEHNT	ETV1	226	P50549
HNIYGFYHQMATAEG	GANC	541	Q8TET4
SYHHQEYNDGRKTFP	MAP3K2	271	Q9Y2U5
QHYKFRYHQQGEGQE	KMT2B	2486	Q9UMN6
HFSTFDGKQYTVHGD	MUC5AC	441	P98088
ANYIDGYHRSNHFIA	PTPRU	946	Q92729
HSGKQVGVYFYDNGH	FBXO11	636	Q86XK2
HKFIEAGQYNSHLYG	DLG4	596	P78352
DGYNVHYGARSIKHE	CLPB	611	Q9H078
FHYQDGAFHTEYNRA	PDIA5	111	Q14554
EGAEGHFDLHYYENQ	OMD	406	Q99983
GSYKEGHNYENNHHF	CWH43	676	Q9H720
HSLDDIYYFGGQNAH	FUT8	491	Q9BYC5
EAVGNGRQATHYYHS	SPHKAP	311	Q2M3C7
GRQATHYYHSEAFKG	SPHKAP	316	Q2M3C7
HMENGGDHRYVNNYT	TRIM29	441	Q14134
ETDSFKLAYGGHQYH	SYNRG	1276	Q9UMZ2
KSYYENAEHHDAGFS	PLEKHG3	721	A1L390
QHFQHGGYQYNHSGF	FAM98A	496	Q8NCA5
GSDPQHYEGNFHYIN	REN	246	P00797
HYEGNFHYINLIKTG	REN	251	P00797
IDKFHYGTHYSNAAG	NBEAL2	2151	Q6ZNJ1
NGNNGYHKDHVYGIH	PROM1	841	O43490
FYGKEHQNYFGIDEN	SIPA1L2	491	Q9P2F8
YHGYTFANLGEHEFV	SAE1	161	Q9UBE0
ENYAFAGMYHVFDQH	WDR13	156	Q9H1Z4
GYSENNVFYGHHAKI	WDR1	521	O75083
YGTAHVHYQVEKLFG	TMEM151A	306	Q8N4L1
DAAYYGNISHFVNHS	SUV39H1	311	O43463
HDGHYFSYVKAQEGQ	USP17L3	331	A6NCW0
FAVYDGHAGSQVAKY	PPM1A	56	P35813
HNHLDYLAKNGYEYE	WDHD1	736	O75717
YHEQGHYEEALSVYK	TMTC2	616	Q8N394
HNGHYFSYVKAQEGQ	USP17L18	331	D6R9N7
HNGHYFSYVKAQEGQ	USP17L5	331	A8MUK1
HNGHYFSYVKAQEGQ	USP17L21	331	D6R901
HNGHYFSYVKAQEGQ	USP17L13	331	C9JLJ4
HNGHYFSYVKAQEGQ	USP17L19	331	D6RCP7
HDGHYFSYVKAQEVQ	USP17L1	331	Q7RTZ2
HYSYGVHDTNKGEVS	TRBV10-1	66	A0A0K0K1A3
HNGHYFSYVKAQEGQ	USP17L12	331	C9JPN9
HNGHYFSYVKAQEGQ	USP17L24	331	Q0WX57
YSSQFIYHQRGHTGE	ZNF227	671	Q86WZ6
HNGHYFSYVKAQEGQ	USP17L7	331	P0C7H9
HNGHYFSYVKAQEGQ	USP17L6P	331	Q6QN14
HYGKIDRQDQSYHYG	RPTN	486	Q6XPR3
HNGHYFSYVKAQEGQ	USP17L22	331	D6RA61
HNGHYFSYVKAQEGQ	USP17L15	331	C9J2P7
HNGHYFSYVKAQEGQ	USP17L17	331	D6RBQ6
EYYKGFDHNSHLHNN	ZNF214	586	Q9UL59
HDGHYFSYVKAQEGQ	USP17L2	331	Q6R6M4
HNGHYFSYVKAQEGQ	USP17L20	331	D6RJB6
HNGHYSSYVKAQEGQ	USP17L10	331	C9JJH3
HNGHYFSYVKAQEGQ	USP17L11	331	C9JVI0
HYRTKDVHFNAYTGA	ART4	186	Q93070
SFGIHHYAGKVLYNA	MYO3A	826	Q8NEV4
IHDGLDFYYSSKQHA	NMD3	191	Q96D46
GKQLSDAVYHYDYVH	NEB	4906	P20929