Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
HumanPheno	Abnormal upper lip morphology	NBAS KMT2D PIEZO2 MCPH1 FIG4 PUF60 EDARADD TRPS1 NSD1 KDM3B EXTL3 HESX1 LARP7 NOTCH3 LUZP1 ZNF292	4.87e-07	980	24	16	HP:0000177
HumanPheno	Single transverse palmar crease	NBAS KMT2D PIEZO2 FIG4 PUF60 TRPS1 EXTL3 ZNF292	3.63e-06	215	24	8	HP:0000954
HumanPheno	Abnormality of the chin	KMT2D PIEZO2 FIG4 PUF60 TRPS1 NSD1 KDM3B EXTL3 LUZP1 ZNF292	7.02e-06	409	24	10	HP:0000306
HumanPheno	Hip dysplasia	KMT2D PIEZO2 FIG4 PUF60 TRPS1 KDM3B EXTL3 LUZP1	1.02e-05	247	24	8	HP:0001385
HumanPheno	Abnormal lip morphology	NBAS KMT2D PIEZO2 MCPH1 FIG4 PUF60 EDARADD TRPS1 NSD1 KDM3B EXTL3 HESX1 LARP7 NOTCH3 LUZP1 ZNF292	1.48e-05	1249	24	16	HP:0000159
HumanPheno	Absent nipple	KMT2D FIG4 EDARADD	1.48e-05	11	24	3	HP:0002561
HumanPheno	Abnormality of the palmar creases	NBAS KMT2D PIEZO2 FIG4 PUF60 TRPS1 EXTL3 ZNF292	1.49e-05	260	24	8	HP:0010490
HumanPheno	Abnormal palmar dermatoglyphics	NBAS KMT2D PIEZO2 FIG4 PUF60 TRPS1 EXTL3 ZNF292	1.71e-05	265	24	8	HP:0001018
HumanPheno	Abnormal cranial suture/fontanelle morphology	KMT2D PIEZO2 FIG4 PPFIBP1 NSD1 EXTL3 HESX1 NOTCH3 LUZP1 ZNF292	2.52e-05	472	24	10	HP:0000235
HumanPheno	Abnormality of the philtrum	NBAS KMT2D PIEZO2 FIG4 PUF60 TRPS1 NSD1 EXTL3 LARP7 NOTCH3 LUZP1 ZNF292	3.34e-05	726	24	12	HP:0000288
HumanPheno	Renal agenesis	KMT2D PIEZO2 MCPH1 PUF60 PPFIBP1 NSD1 HESX1	3.38e-05	209	24	7	HP:0000104
HumanPheno	Abnormal hip joint morphology	COL5A1 KMT2D PIEZO2 FIG4 PUF60 TRPS1 NSD1 KDM3B EXTL3 LUZP1	3.50e-05	490	24	10	HP:0001384
HumanPheno	Abnormality of cranial sutures	KMT2D FIG4 PPFIBP1 NSD1 EXTL3 HESX1 NOTCH3 LUZP1 ZNF292	3.67e-05	388	24	9	HP:0011329
HumanPheno	Abnormal synovial membrane morphology	COL5A1 KMT2D PIEZO2 FIG4 PUF60 TRPS1 NSD1 KDM3B EXTL3 LUZP1	4.40e-05	503	24	10	HP:0005262
HumanPheno	Sparse eyebrow	KMT2D FIG4 EDARADD TRPS1 NSD1 LARP7	5.31e-05	151	24	6	HP:0045075
HumanPheno	Abnormality of the forehead	NBAS KMT2D MCPH1 FIG4 PUF60 PPFIBP1 EDARADD TRPS1 NSD1 EXTL3 HESX1 LARP7 NOTCH3 LUZP1 ZNF292	5.56e-05	1208	24	15	HP:0000290
HumanPheno	Abnormal dermatoglyphics	NBAS KMT2D PIEZO2 FIG4 PUF60 TRPS1 EXTL3 ZNF292	5.87e-05	314	24	8	HP:0007477
HumanPheno	Shoulder subluxation	COL5A1 PUF60	6.36e-05	3	24	2	HP:0003835
HumanPheno	Abnormal hip bone morphology	COL5A1 KMT2D PIEZO2 FIG4 PUF60 TRPS1 NSD1 KDM3B EXTL3 HESX1 LUZP1	7.25e-05	653	24	11	HP:0003272
HumanPheno	Short stature	COL5A1 NBAS KMT2D PIEZO2 MCPH1 FIG4 PUF60 PPFIBP1 TRPS1 NSD1 KDM3B EXTL3 HESX1 LARP7 NOTCH3 LUZP1	7.38e-05	1407	24	16	HP:0004322
HumanPheno	Hyperextensible skin	COL5A1 NBAS FIG4 PUF60 TRPS1 NSD1	7.89e-05	162	24	6	HP:0000974
HumanPheno	Thin vermilion border	NBAS KMT2D PIEZO2 MCPH1 FIG4 PUF60 TRPS1 KDM3B ZNF292	8.76e-05	433	24	9	HP:0000233
HumanPheno	Bilateral tonic-clonic seizure with focal onset	PDSS2 KMT2D FIG4 PPFIBP1	8.82e-05	52	24	4	HP:0007334
HumanPheno	Thin upper lip vermilion	KMT2D PIEZO2 MCPH1 FIG4 PUF60 TRPS1 KDM3B ZNF292	1.01e-04	339	24	8	HP:0000219
HumanPheno	Thin lips	KMT2D PIEZO2 MCPH1 FIG4 PUF60 TRPS1 KDM3B ZNF292	1.01e-04	339	24	8	HP:0000213
HumanPheno	Abnormally lax or hyperextensible skin	COL5A1 NBAS FIG4 PUF60 TRPS1 NSD1	1.37e-04	179	24	6	HP:0008067
HumanPheno	Prominent forehead	KMT2D PUF60 EDARADD NSD1 HESX1 LARP7 ZNF292	1.40e-04	261	24	7	HP:0011220
HumanPheno	Abnormality of upper lip vermillion	KMT2D PIEZO2 MCPH1 FIG4 PUF60 EDARADD TRPS1 KDM3B ZNF292	1.50e-04	464	24	9	HP:0011339
HumanPheno	Abnormal pelvic girdle bone morphology	COL5A1 KMT2D PIEZO2 FIG4 PUF60 TRPS1 NSD1 KDM3B EXTL3 HESX1 LUZP1	2.04e-04	730	24	11	HP:0002644
HumanPheno	Narrow palate	KMT2D PIEZO2 FIG4 TRPS1 NSD1 NOTCH3	2.67e-04	202	24	6	HP:0000189
HumanPheno	Abnormal cerebral subcortex morphology	PDSS2 KMT2D PIEZO2 MCPH1 FIG4 PUF60 PPFIBP1 NSD1 KDM3B PRKN EXTL3 HESX1 NOTCH3 LUZP1	2.78e-04	1207	24	14	HP:0010993
HumanPheno	Focal motor seizure	PDSS2 KMT2D FIG4 PPFIBP1 EXTL3	2.99e-04	131	24	5	HP:0011153
HumanPheno	Branchial cyst	KMT2D PUF60	3.15e-04	6	24	2	HP:0009796
HumanPheno	Bilateral renal hypoplasia	KMT2D PUF60	3.15e-04	6	24	2	HP:0012584
HumanPheno	Abnormal middle phalanx morphology of the hand	KMT2D FIG4 PUF60 TRPS1	3.32e-04	73	24	4	HP:0009833
HumanPheno	Abnormal external nose morphology	KMT2D PIEZO2 FIG4 PUF60 EDARADD TRPS1 NSD1 KDM3B EXTL3 HESX1 LUZP1 ZNF292	3.43e-04	916	24	12	HP:0010938
HumanPheno	Abnormal eyelid morphology	COL5A1 NBAS KMT2D PIEZO2 MCPH1 FIG4 PUF60 EDARADD TRPS1 NSD1 EXTL3 LARP7 NOTCH3 LUZP1 ZNF292	3.64e-04	1408	24	15	HP:0000492
HumanPheno	Short phalanx of finger	KMT2D PIEZO2 FIG4 PUF60 TRPS1 NSD1 EXTL3	3.75e-04	306	24	7	HP:0009803
HumanPheno	Aplasia/Hypoplasia of the eyebrow	KMT2D FIG4 EDARADD TRPS1 NSD1 LARP7	3.84e-04	216	24	6	HP:0100840
HumanPheno	Abnormal skin morphology of the palm	NBAS KMT2D PIEZO2 FIG4 PUF60 TRPS1 EXTL3 ZNF292	4.01e-04	413	24	8	HP:0040211
HumanPheno	Abnormal cardiac septum morphology	KMT2D PIEZO2 FIG4 PUF60 PPFIBP1 NSD1 KDM3B LARP7 NOTCH3 LUZP1 MYLK2	4.02e-04	787	24	11	HP:0001671
HumanPheno	Dolichocephaly	COL5A1 KMT2D FIG4 NSD1 EXTL3 NOTCH3	4.14e-04	219	24	6	HP:0000268
HumanPheno	Ventriculomegaly	KMT2D PIEZO2 MCPH1 FIG4 PUF60 PPFIBP1 TRPS1 NSD1 EXTL3 LUZP1 ZNF292	4.16e-04	790	24	11	HP:0002119
HumanPheno	Inguinal hernia	COL5A1 KMT2D PIEZO2 PUF60 NSD1 KDM3B NOTCH3	4.23e-04	312	24	7	HP:0000023
HumanPheno	Abnormal calvaria morphology	COL5A1 NBAS KMT2D PIEZO2 FIG4 PPFIBP1 EDARADD TRPS1 NSD1 EXTL3 HESX1 NOTCH3 LUZP1 ZNF292	4.27e-04	1254	24	14	HP:0002683
HumanPheno	Aplasia/Hypoplasia of the phalanges of the hand	KMT2D PIEZO2 FIG4 PUF60 TRPS1 NSD1 EXTL3	4.84e-04	319	24	7	HP:0009767
HumanPheno	Brachydactyly	NBAS KMT2D PIEZO2 FIG4 PUF60 TRPS1 NSD1 EXTL3 HESX1 LUZP1	5.00e-04	670	24	10	HP:0001156
HumanPheno	Short digit	NBAS KMT2D PIEZO2 FIG4 PUF60 TRPS1 NSD1 EXTL3 HESX1 LUZP1	5.13e-04	672	24	10	HP:0011927
HumanPheno	Long philtrum	NBAS PIEZO2 PUF60 TRPS1 NSD1 EXTL3 NOTCH3 LUZP1	5.20e-04	429	24	8	HP:0000343
HumanPheno	Abnormal eyebrow morphology	NBAS KMT2D FIG4 PUF60 EDARADD TRPS1 NSD1 LARP7 LUZP1 ZNF292	5.25e-04	674	24	10	HP:0000534
HumanPheno	Brachydactyly (hand)	KMT2D PIEZO2 FIG4 PUF60 TRPS1 NSD1 EXTL3 HESX1	5.29e-04	430	24	8	HP:0100667
HumanPheno	Congenital hip dislocation	KMT2D PIEZO2 FIG4 PUF60	5.69e-04	84	24	4	HP:0001374
HumanPheno	Sparse lateral eyebrow	KMT2D EDARADD TRPS1	5.93e-04	36	24	3	HP:0005338
HumanPheno	Sparse and thin eyebrow	KMT2D EDARADD TRPS1	5.93e-04	36	24	3	HP:0000535
HumanPheno	Abnormal elasticity of skin	COL5A1 NBAS FIG4 PUF60 TRPS1 NSD1	6.46e-04	238	24	6	HP:0010647
HumanPheno	High, narrow palate	KMT2D PIEZO2 FIG4 NSD1 NOTCH3	6.70e-04	156	24	5	HP:0002705
HumanPheno	Hypoplastic nipples	KMT2D FIG4 EDARADD	7.52e-04	39	24	3	HP:0002557
HumanPheno	Renal hypoplasia/aplasia	KMT2D PIEZO2 MCPH1 PUF60 PPFIBP1 NSD1 HESX1	9.86e-04	359	24	7	HP:0008678
HumanPheno	Abnormal sternum morphology	COL5A1 PIEZO2 FIG4 PUF60 TRPS1 NSD1 EXTL3 NOTCH3	1.02e-03	474	24	8	HP:0000766
HumanPheno	Abnormal nasal bridge morphology	KMT2D PIEZO2 PUF60 EDARADD TRPS1 NSD1 EXTL3 HESX1 LARP7 NOTCH3 LUZP1 ZNF292	1.04e-03	1029	24	12	HP:0000422
HumanPheno	Abnormality of the palpebral fissures	COL5A1 KMT2D PIEZO2 MCPH1 FIG4 PUF60 NSD1 EXTL3 LARP7 NOTCH3 ZNF292	1.08e-03	880	24	11	HP:0008050
HumanPheno	Agenesis of corpus callosum	PIEZO2 MCPH1 FIG4 PUF60 NSD1 HESX1 LUZP1	1.09e-03	365	24	7	HP:0001274
HumanPheno	Abnormal finger phalanx morphology	COL5A1 KMT2D PIEZO2 FIG4 PUF60 TRPS1 NSD1 EXTL3 HESX1 LUZP1	1.09e-03	738	24	10	HP:0005918
HumanPheno	Unilateral renal agenesis	KMT2D MCPH1 PUF60 PPFIBP1	1.14e-03	101	24	4	HP:0000122
HumanPheno	Abnormal vertebral morphology	KMT2D PIEZO2 FIG4 PUF60 NSD1 EXTL3 HESX1 NOTCH3	1.15e-03	483	24	8	HP:0003468
HumanPheno	Deeply set eye	COL5A1 PIEZO2 PUF60 EXTL3 LARP7 LUZP1	1.16e-03	266	24	6	HP:0000490
HumanPheno	Abnormal cerebral ventricle morphology	KMT2D PIEZO2 MCPH1 FIG4 PUF60 PPFIBP1 TRPS1 NSD1 EXTL3 NOTCH3 LUZP1 ZNF292	1.22e-03	1046	24	12	HP:0002118
HumanPheno	Epicanthus	COL5A1 NBAS KMT2D PIEZO2 FIG4 PUF60 NOTCH3 LUZP1 ZNF292	1.24e-03	614	24	9	HP:0000286
HumanPheno	Hypospadias	KMT2D PIEZO2 FIG4 PUF60 NSD1 KDM3B LUZP1	1.32e-03	377	24	7	HP:0000047
HumanPheno	Abnormal facial shape	COL5A1 NBAS KMT2D PIEZO2 FIG4 PUF60 EDARADD TRPS1 NSD1 EXTL3 HESX1 LARP7 NOTCH3	1.35e-03	1221	24	13	HP:0001999
HumanPheno	Neoplasm of the middle ear	KMT2D NSD1	1.36e-03	12	24	2	HP:0100799
HumanPheno	Phimosis	KMT2D NSD1	1.36e-03	12	24	2	HP:0001741
HumanPheno	Cholesteatoma	KMT2D NSD1	1.36e-03	12	24	2	HP:0009797
HumanPheno	Chiari type I malformation	KMT2D PIEZO2 NOTCH3	1.38e-03	48	24	3	HP:0007099
HumanPheno	Smooth philtrum	KMT2D PUF60 TRPS1 NOTCH3 ZNF292	1.45e-03	185	24	5	HP:0000319
HumanPheno	Abnormal nasal tip morphology	KMT2D PUF60 TRPS1 NSD1 KDM3B EXTL3 ZNF292	1.51e-03	386	24	7	HP:0000436
HumanPheno	Aplasia/Hypoplasia of the corpus callosum	KMT2D PIEZO2 MCPH1 FIG4 PUF60 PPFIBP1 NSD1 EXTL3 HESX1 LUZP1	1.56e-03	772	24	10	HP:0007370
HumanPheno	Hernia of the abdominal wall	COL5A1 KMT2D PIEZO2 PUF60 NSD1 KDM3B HESX1 NOTCH3	1.56e-03	506	24	8	HP:0004299
HumanPheno	Fine hair	NBAS EDARADD TRPS1 NSD1	1.57e-03	110	24	4	HP:0002213
HumanPheno	Abnormally low-pitched voice	TRPS1 NSD1	1.61e-03	13	24	2	HP:0010300
HumanPheno	Joint dislocation	COL5A1 KMT2D PIEZO2 FIG4 PUF60 TRPS1 EXTL3	1.61e-03	390	24	7	HP:0001373
HumanPheno	Kyphosis	KMT2D PIEZO2 FIG4 PUF60 NSD1 EXTL3 NOTCH3 LUZP1	1.65e-03	510	24	8	HP:0002808
HumanPheno	Ventricular septal defect	KMT2D PIEZO2 FIG4 PUF60 PPFIBP1 NSD1 KDM3B NOTCH3	1.65e-03	510	24	8	HP:0001629
HumanPheno	Abnormal morphology of the nasal alae	KMT2D PIEZO2 FIG4 PUF60 TRPS1 NSD1 KDM3B EXTL3 ZNF292	1.65e-03	639	24	9	HP:0000429
HumanPheno	Abdominal wall defect	COL5A1 KMT2D PIEZO2 PUF60 NSD1 KDM3B HESX1 NOTCH3	1.67e-03	511	24	8	HP:0010866
HumanPheno	Thoracoabdominal wall defect	COL5A1 KMT2D PIEZO2 PUF60 NSD1 KDM3B HESX1 NOTCH3	1.67e-03	511	24	8	HP:0100656
HumanPheno	Dysplastic corpus callosum	PIEZO2 MCPH1 FIG4 PUF60 NSD1 HESX1 LUZP1	1.73e-03	395	24	7	HP:0006989
HumanPheno	Displacement of the urethral meatus	KMT2D PIEZO2 FIG4 PUF60 NSD1 KDM3B LUZP1	1.79e-03	397	24	7	HP:0100627
HumanPheno	Abnormality of hair texture	NBAS FIG4 EDARADD TRPS1 NSD1 NOTCH3	1.82e-03	290	24	6	HP:0010719
HumanPheno	Abnormal male urethral meatus morphology	KMT2D PIEZO2 FIG4 PUF60 NSD1 KDM3B LUZP1	1.84e-03	399	24	7	HP:0032076
HumanPheno	Abnormality of the lower urinary tract	COL5A1 KMT2D PIEZO2 MCPH1 FIG4 PUF60 TRPS1 NSD1 KDM3B NOTCH3 LUZP1	1.84e-03	937	24	11	HP:0010936
HumanPheno	Abnormal corpus callosum morphology	KMT2D PIEZO2 MCPH1 FIG4 PUF60 PPFIBP1 NSD1 KDM3B EXTL3 HESX1 LUZP1	1.84e-03	937	24	11	HP:0001273
HumanPheno	Abnormal ventricular septum morphology	KMT2D PIEZO2 FIG4 PUF60 PPFIBP1 NSD1 KDM3B NOTCH3	1.89e-03	521	24	8	HP:0010438
HumanPheno	Abnormal palm morphology	NBAS KMT2D PIEZO2 FIG4 PUF60 TRPS1 EXTL3 ZNF292	1.89e-03	521	24	8	HP:0100871
Domain	Post-SET_dom	KMT2D NSD1	2.20e-03	16	82	2	IPR003616
Domain	PostSET	KMT2D NSD1	2.20e-03	16	82	2	SM00508
Domain	POST_SET	KMT2D NSD1	2.20e-03	16	82	2	PS50868
Domain	RRM_1	RBPMS PUF60 EIF4B RAVER2 LARP7	2.22e-03	208	82	5	PF00076
Domain	RRM	RBPMS PUF60 EIF4B RAVER2 LARP7	2.67e-03	217	82	5	SM00360
Domain	RRM_dom	RBPMS PUF60 EIF4B RAVER2 LARP7	3.24e-03	227	82	5	IPR000504
Domain	RRM	RBPMS PUF60 EIF4B RAVER2 LARP7	3.43e-03	230	82	5	PS50102
Domain	-	RBPMS PUF60 EIF4B RAVER2 LARP7	4.40e-03	244	82	5	3.30.70.330
Domain	-	SEC14L6 MCF2L2	4.54e-03	23	82	2	3.40.525.10
Domain	SEC14	SEC14L6 MCF2L2	5.35e-03	25	82	2	SM00516
Domain	Nucleotide-bd_a/b_plait	RBPMS PUF60 EIF4B RAVER2 LARP7	5.56e-03	258	82	5	IPR012677
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CEP350 WWC2 MTMR12 ZCCHC8 PPFIBP1 EIF4B CCSER2 KDM3B PARD3B RICTOR MARK2 EIF4G3 LUZP1 MYLK2 SAMD4A	1.81e-09	861	83	15	36931259
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	DAB2IP ZFYVE16 PUF60 PPFIBP1 RTN4 EIF4B CCSER2 MARK2 NOTCH3 LUZP1 SLC3A2	1.06e-07	565	83	11	25468996
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	DAB2IP FAT1 PIEZO2 GPR158 PPFIBP1 CD44 ASAP3 RICTOR MARK2 PARP14 SLC3A2	1.14e-07	569	83	11	30639242
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ELOB INTS2 ZCCHC8 PPFIBP1 EIF4B TRPS1 NSD1 GEMIN5 RICTOR MARK2 SPATS2 EIF4G3 LARP7 LUZP1 MYLK2 SLC3A2	4.34e-07	1497	83	16	31527615
Pubmed	The interaction of the von Hippel-Lindau tumor suppressor and heterochromatin protein 1.	ELOB RBPMS CD44 SLC3A2	5.91e-07	28	83	4	22234250
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	KMT2D FAM193A ZNF608 ZFYVE16 ZCCHC8 TRPS1 GEMIN5 MGA LUZP1	7.20e-07	418	83	9	34709266
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	COL5A1 FAT1 RBPMS PIEZO2 SEC14L6 ZNF608 AVL9 PUF60 RTN4 NSD1 SPATS2 EIF4G3 LARP7 SLC3A2	1.04e-06	1215	83	14	15146197
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	CEP350 FAM193A RTN4 EIF4B CD44 GEMIN5 SPATS2 EIF4G3 MGA LUZP1 ZNF292	1.22e-06	724	83	11	36232890
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	MTMR12 FAM193A ZCCHC8 PPFIBP1 CCSER2 RICTOR MARK2 LUZP1 SAMD4A	1.23e-06	446	83	9	24255178
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	KMT2D ZNF608 TRPS1 NSD1 ZNF292	1.72e-06	83	83	5	28794006
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ELOB FAM193A ZFYVE16 PUF60 ZCCHC8 RTN4 EIF4B KDM3B GEMIN5 EIF4G3 NEDD1 SLC3A2	2.21e-06	934	83	12	33916271
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	PPFIBP1 PARD3B RICTOR MARK2 SAMD4A	4.76e-06	102	83	5	15778465
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	KMT2D ZNF608 TRPS1 GEMIN5 RO60 PFKFB3 MGA ZNF292	5.12e-06	398	83	8	35016035
Pubmed	Emk, a protein kinase with homologs in yeast maps to mouse chromosome 19.	MARK2 SLC3A2	5.63e-06	2	83	2	8358177
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	CEP350 PPP1R26 FAT1 GARIN3 PPFIBP1 TRPS1 MGA TARBP1 SLC3A2 SAMD4A	5.78e-06	689	83	10	36543142
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	DAB2IP CEP350 WWC2 ZCCHC8 EIF4B AP3M2 KDM3B RICTOR TRAK2 SPATS2 NEDD1 SAMD4A	6.47e-06	1038	83	12	26673895
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	ZNF608 RTN4 EIF4B KDM3B NEDD1 MGA LUZP1 SLC3A2	1.13e-05	444	83	8	34795231
Pubmed	CDK7/GRP78 signaling axis contributes to tumor growth and metastasis in osteosarcoma.	MCPH1 PUF60 RTN4 EIF4B CD44 TRAK2 LUZP1 SLC3A2	1.65e-05	468	83	8	36042349
Pubmed	Radiogenomics in head and neck cancer: correlation of radiomic heterogeneity and somatic mutations in TP53, FAT1 and KMT2D.	FAT1 KMT2D	1.69e-05	3	83	2	31123786
Pubmed	Blockade of Notch3 inhibits the stem-like property and is associated with ALDH1A1 and CD44 via autophagy in non-small lung cancer.	CD44 NOTCH3	1.69e-05	3	83	2	27035162
Pubmed	Human Y5 RNA specializes a Ro ribonucleoprotein for 5S ribosomal RNA quality control.	PUF60 RO60	1.69e-05	3	83	2	18056422
Pubmed	Targeting miR-21-3p inhibits proliferation and invasion of ovarian cancer cells.	RBPMS ZNF608	3.37e-05	4	83	2	27166999
Pubmed	The Deubiquitylase OTUB1 Mediates Ferroptosis via Stabilization of SLC7A11.	CD44 SLC3A2	3.37e-05	4	83	2	30709928
Pubmed	PARK2 regulates eIF4B-driven lymphomagenesis.	EIF4B PRKN	3.37e-05	4	83	2	35191952
Pubmed	High-Molecular-Weight Hyaluronan Is a Hippo Pathway Ligand Directing Cell Density-Dependent Growth Inhibition via PAR1b.	CD44 MARK2	3.37e-05	4	83	2	31080060
Pubmed	PARK2 regulates eIF4B-driven lymphomagenesis.	EIF4B PRKN	3.37e-05	4	83	2	35105670
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	COL5A1 NBAS ELOB ZCCHC8 PPFIBP1 RTN4 CD44 GEMIN5 EXTL3 PFKFB3 LARP7 SLC3A2 SAMD4A	3.54e-05	1440	83	13	30833792
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	DAB2IP CEP350 WWC2 MTMR12 KMT2D ZFYVE16 TRPS1 CD44 RICTOR LUZP1 SLC3A2	3.96e-05	1049	83	11	27880917
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	KMT2D ZNF608 ZCCHC8 TRPS1 KDM3B MGA	4.55e-05	268	83	6	33640491
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PCNX2 COL5A1 MCPH1 ZNF608 INTS2 GPR158 TRPS1 PARD3B PRKN SPATS2 EIF4G3 NEDD1 NOTCH3	4.99e-05	1489	83	13	28611215
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KMT2D PUF60 NSD1 KDM3B GEMIN5 MGA LUZP1 SLC3A2	5.12e-05	549	83	8	38280479
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	ELOB PUF60 PPFIBP1 RTN4 MCC PIP5K1B RO60 PFKFB3 MARK2 EIF4G3 SLC3A2 SAMD4A	5.25e-05	1284	83	12	17353931
Pubmed	Mitogen-inducible SIPA1 is mapped to the conserved syntenic groups of chromosome 19 in mouse and chromosome 11q13.3 centromeric to BCL1 in human.	MARK2 SLC3A2	5.60e-05	5	83	2	9027487
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	ZFYVE16 AVL9 FIG4 AP3M2 MARK2 SLC3A2	6.39e-05	285	83	6	34369648
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	CEP350 NBAS FAM193A ZFYVE16 MCC KDM3B NEDD1 MGA SLC3A2	6.40e-05	733	83	9	34672954
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	CEP350 ELOB INTS2 PPFIBP1 RTN4 MARK2 SPATS2 NEDD1 LARP7	7.93e-05	754	83	9	33060197
Pubmed	Functional reprogramming of regulatory T cells in the absence of Foxp3.	RICTOR PFKFB3	8.39e-05	6	83	2	31384057
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	CEP350 FAT1 PPFIBP1 CD44 KDM3B RICTOR EIF4G3 MGA SLC3A2	9.96e-05	777	83	9	35844135
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ZNF608 INTS2 PPFIBP1 PARP14	1.11e-04	103	83	4	10574462
Pubmed	Genetic mapping of the galanin-GMAP (Galn) gene to mouse chromosome 19.	MARK2 SLC3A2	1.17e-04	7	83	2	9501310
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	TRAK2 EXTL3 MGA ZNF292	1.20e-04	105	83	4	9628581
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	ELOB KMT2D INTS2 ZCCHC8 PARD3B PARP14 LUZP1	1.33e-04	469	83	7	27634302
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	CEP350 FAM193A PPFIBP1 TRAK2 LUZP1	1.48e-04	209	83	5	36779422
Pubmed	Definition of the minimal MEN1 candidate area based on a 5-Mb integrated map of proximal 11q13. The European Consortium on Men1, (GENEM 1; Groupe d'Etude des Néoplasies Endocriniennes Multiples de type 1).	MARK2 SLC3A2	1.56e-04	8	83	2	8938448
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CEP350 PPP1R26 FIG4 PPFIBP1 RICTOR FHDC1 MGA	1.81e-04	493	83	7	15368895
Pubmed	Integrated Proteomics-Based Physical and Functional Mapping of AXL Kinase Signaling Pathways and Inhibitors Define Its Role in Cell Migration.	RTN4 CD44 SLC3A2	1.85e-04	46	83	3	35022314
Pubmed	Oxidative stress-induced signaling pathways implicated in the pathogenesis of Parkinson's disease.	PRKN MARK2	2.00e-04	9	83	2	24522549
Pubmed	Mutation discovery in mice by whole exome sequencing.	NOTCH3 SAMD4A	2.00e-04	9	83	2	21917142
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	DAB2IP ZNF608 GPR158 PPFIBP1 KDM3B	2.09e-04	225	83	5	12168954
Pubmed	Plk4 Promotes Cancer Invasion and Metastasis through Arp2/3 Complex Regulation of the Actin Cytoskeleton.	CEP350 CCSER2 NEDD1	2.10e-04	48	83	3	27872092
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	ELOB FAM193A PUF60 ZCCHC8 EIF4B GEMIN5 RO60 MARK2	2.18e-04	678	83	8	30209976
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CEP350 ZCCHC8 PPFIBP1 TRPS1 MCF2L2 EXTL3 ZNF227 ARMCX4 EIF4G3 TARBP1 ZNF292	2.37e-04	1285	83	11	35914814
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	PUF60 ZCCHC8 EIF4B KDM3B	2.73e-04	130	83	4	35545047
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	PPFIBP1 CD44 PARD3B RICTOR MARK2 SLC3A2	2.92e-04	377	83	6	38117590
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	ZFYVE16 PPFIBP1 RTN4 EIF4B RICTOR MARK2 EIF4G3 SLC3A2	2.92e-04	708	83	8	39231216
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	CEP350 INTS2 NSD1 MARK2 EIF4G3	2.92e-04	242	83	5	34011540
Pubmed	SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.	MTMR12 PPFIBP1 EIF4B RICTOR PFKFB3 MGA	2.96e-04	378	83	6	34315543
Pubmed	Analysis of HIV-1 Gag protein interactions via biotin ligase tagging.	EIF4B GEMIN5 SLC3A2	2.98e-04	54	83	3	25631074
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DAB2IP PCNX2 PPP1R26 FAT1 KMT2D PUF60 NSD1 KDM3B GEMIN5 EXTL3	3.00e-04	1105	83	10	35748872
Pubmed	The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2.	TRAK2 ARMCX4	3.05e-04	11	83	2	22569362
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	FAT1 ZNF608 ZCCHC8 TAF7L TRPS1 MCC RICTOR MGA LARP7 LUZP1	3.24e-04	1116	83	10	31753913
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	RBPMS PUF60 EIF4B CCSER2 PARD3B TRAK2 SPATS2 LARP7	3.36e-04	723	83	8	34133714
Pubmed	New nomenclature for chromatin-modifying enzymes.	KMT2D NSD1 KDM3B	3.49e-04	57	83	3	18022353
Pubmed	A glycolytic shift in Schwann cells supports injured axons.	RICTOR PFKFB3	3.66e-04	12	83	2	32807950
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	RTN4 EIF4B GEMIN5 LUZP1 SLC3A2	3.78e-04	256	83	5	33397691
Pubmed	rec-YnH enables simultaneous many-by-many detection of direct protein-protein and protein-RNA interactions.	RBPMS CCSER2 PARD3B MARK2	3.81e-04	142	83	4	30217970
Pubmed	The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53.	PUF60 GEMIN5 EIF4G3	3.87e-04	59	83	3	32382008
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	NBAS PUF60 PPFIBP1 RTN4 CD44 LUZP1 SLC3A2	4.25e-04	568	83	7	37774976
Pubmed	Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients.	MCC B3GAT2	4.31e-04	13	83	2	21326311
Pubmed	An E3 ubiquitin ligase, Really Interesting New Gene (RING) Finger 41, is a candidate gene for anxiety-like behavior and beta-carboline-induced seizures.	RTN4 KDM3B	4.31e-04	13	83	2	18986647
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	KMT2D ZCCHC8 MARK2 SPATS2 PARP14 MGA	4.55e-04	410	83	6	26949251
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	ZNF608 INTS2 KDM3B PFKFB3 MGA	4.98e-04	272	83	5	31010829
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	DAB2IP PPFIBP1 PARD3B RICTOR MARK2 SLC3A2	5.23e-04	421	83	6	36976175
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	WWC2 MTMR12 ZFYVE16 RTN4 MCC MARK2 NEDD1 LUZP1 SLC3A2	5.26e-04	974	83	9	28675297
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	WWC2 KMT2D ZCCHC8 EIF4B KDM3B GEMIN5 RICTOR MARK2	5.27e-04	774	83	8	15302935
Pubmed	Comparative mapping of two adjacent regions of MMU19 with their human counterpart on HSA11q13.	MARK2 SLC3A2	5.79e-04	15	83	2	9730611
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	DAB2IP PUF60 EIF4B MARK2 SPATS2 LUZP1	5.84e-04	430	83	6	32581705
Pubmed	Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.	DAB2IP PIEZO2 CD44	6.66e-04	71	83	3	23400010
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	PRKN NEDD1 NOTCH3 LUZP1	7.17e-04	168	83	4	30631154
Pubmed	Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.	ZCCHC8 GEMIN5 MGA LUZP1	7.33e-04	169	83	4	31462741
Pubmed	Cell cycle gene-specific control of transcription has a critical role in proliferation of primordial germ cells.	TDRD1 LARP7	7.48e-04	17	83	2	23154982
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	ELOB MCPH1 NSD1 MGA LUZP1 SLC3A2	7.65e-04	453	83	6	29656893
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	ELOB ZNF608 PUF60 RTN4 EIF4B MARK2 SPATS2 MGA LARP7 LUZP1	7.67e-04	1247	83	10	27684187
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	NBAS ELOB FAM193A PPFIBP1 RTN4 CCSER2 RICTOR MARK2 EIF4G3 LARP7 SLC3A2	8.05e-04	1487	83	11	33957083
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	CEP350 MGA SLC3A2	8.13e-04	76	83	3	27542412
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	CEP350 KMT2D TRPS1 KDM3B ZNF227 TARBP1 SLC3A2	8.42e-04	638	83	7	31182584
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	CEP350 FAT1 PUF60 PPFIBP1 PARD3B MARK2 NEDD1	8.50e-04	639	83	7	23443559
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZCCHC8 ZNF805 ZNF227 ZNF543	9.47e-04	181	83	4	37372979
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	COL5A1 PUF60 ZCCHC8 NSD1 GEMIN5 EIF4G3 LARP7	9.64e-04	653	83	7	22586326
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	FAT1 RBPMS INTS2 RTN4 CD44 EXTL3 MARK2 NEDD1 NOTCH3	9.64e-04	1061	83	9	33845483
Pubmed	Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.	PPFIBP1 AP3M2 RICTOR MARK2	9.86e-04	183	83	4	31932471
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	CEP350 ELOB PPFIBP1 EIF4B PARD3B NEDD1 MGA LUZP1	9.89e-04	853	83	8	28718761
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	INTS2 RTN4 EIF4B GEMIN5 PFKFB3 MGA SLC3A2	9.98e-04	657	83	7	36180527
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	CEP350 KMT2D FAM193A MGA	1.01e-03	184	83	4	32908313
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	COL5A1 FAT1 ZFYVE16 PPFIBP1 RTN4 EIF4B KDM3B GEMIN5 NEDD1 LUZP1	1.03e-03	1297	83	10	33545068
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	EIF4B TRPS1 GEMIN5 SPATS2 NEDD1	1.05e-03	321	83	5	32098917
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	CEP350 PUF60 TRPS1 GEMIN5 RICTOR EIF4G3 LARP7	1.12e-03	670	83	7	22990118
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	DAB2IP WWC2 INTS2 EIF4B CCSER2 NSD1 GEMIN5 RICTOR MGA	1.12e-03	1084	83	9	11544199
Pubmed	Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	INTS2 GEMIN5 LUZP1	1.12e-03	85	83	3	15449545
Pubmed	Partners of wild type Grb7 and a mutant lacking its calmodulin-binding domain.	PUF60 EIF4B	1.15e-03	21	83	2	32360748
Interaction	YWHAG interactions	DAB2IP CEP350 WWC2 MTMR12 PUF60 PPFIBP1 EIF4B CCSER2 MCC KDM3B PARD3B PRKN RICTOR PFKFB3 MARK2 EIF4G3 LUZP1 MYLK2 SAMD4A	4.53e-07	1248	82	19	int:YWHAG
Interaction	YWHAH interactions	DAB2IP CEP350 WWC2 MTMR12 ZCCHC8 PPFIBP1 EIF4B CCSER2 KDM3B PARD3B PRKN RICTOR PFKFB3 MARK2 EIF4G3 LUZP1 SAMD4A	1.72e-06	1102	82	17	int:YWHAH
Interaction	YWHAB interactions	DAB2IP CEP350 WWC2 MTMR12 ZCCHC8 PPFIBP1 EIF4B CCSER2 MCC PARD3B PRKN RICTOR PFKFB3 MARK2 LUZP1 SAMD4A	2.73e-06	1014	82	16	int:YWHAB
Interaction	MAD2L1 interactions	DAB2IP FAT1 ZCCHC8 TRPS1 KDM3B GEMIN5 MGA LUZP1	8.58e-06	252	82	8	int:MAD2L1
Interaction	SFN interactions	CEP350 WWC2 MTMR12 PPFIBP1 EIF4B CCSER2 PARD3B PRKN RICTOR MARK2 LUZP1 SAMD4A	2.24e-05	692	82	12	int:SFN
Interaction	YWHAE interactions	DAB2IP WWC2 MTMR12 PPFIBP1 EIF4B CCSER2 MCC PARD3B PRKN RICTOR RO60 MSANTD4 MARK2 MGA LUZP1 SAMD4A	3.94e-05	1256	82	16	int:YWHAE
Interaction	YWHAQ interactions	DAB2IP CEP350 WWC2 MTMR12 PPFIBP1 EIF4B CCSER2 PARD3B PRKN RICTOR PFKFB3 MARK2 LUZP1 MYLK2 SAMD4A	3.96e-05	1118	82	15	int:YWHAQ
Cytoband	8p11.2	AP3M2 ADAM2	2.90e-04	14	83	2	8p11.2
Cytoband	1q42.3	EDARADD TARBP1	3.34e-04	15	83	2	1q42.3
Cytoband	19q13.43	USP29 ZNF805 ZNF543	5.41e-04	87	83	3	19q13.43
Cytoband	12q13.12	KMT2D SPATS2	2.18e-03	38	83	2	12q13.12
Cytoband	1p36.12	ASAP3 EIF4G3	2.29e-03	39	83	2	1p36.12
Cytoband	Xq22.1	TAF7L ARMCX4	2.78e-03	43	83	2	Xq22.1
GeneFamily	RNA binding motif containing	RBPMS PUF60 EIF4B RAVER2 LARP7	4.28e-04	213	54	5	725
Coexpression	NAKAYA_PBMC_FLUMIST_AGE_18_50YO_3DY_DN	MCPH1 PPFIBP1 RTN4 CD44 ZNF805 AP3M2 RICTOR RO60 EIF4G3 NEDD1 ZNF292	8.70e-06	680	82	11	M41089
Coexpression	AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN	ELOB PDSS2 RBPMS FIG4 EIF4B EXTL3 SPATS2	9.66e-06	237	82	7	M8897
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	CEP350 NBAS FAT1 RBPMS FAM193A ZFYVE16 AVL9 CCSER2 KDM3B EIF4G3 SAMD4A ZNF292	1.38e-05	856	82	12	M4500
Coexpression	LAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2	RBPMS PPFIBP1 PARD3B PRKN EIF4G3 SAMD4A	1.93e-05	176	82	6	M39223
Coexpression	GSE11924_TFH_VS_TH17_CD4_TCELL_UP	KMT2D ZFYVE16 AVL9 CCSER2 FHDC1 EXTL3	3.85e-05	199	82	6	M3156
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	CEP350 PCNX2 KMT2D EIF4B TRPS1 CCSER2 CD44 NSD1 OAS2 EVI2B RICTOR RO60 PARP14 LUZP1 ZNF292	5.37e-05	1492	82	15	M40023
Coexpression	CUI_TCF21_TARGETS_2_DN	WWC2 RBPMS ZFYVE16 MCC PARD3B RICTOR RO60 TRAK2 PFKFB3 PARP14 SAMD4A	7.00e-05	854	82	11	M1533
ToppCell	Control-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	PCNX2 TRPS1 CD44 AP3M2 PFKFB3 LUZP1	1.76e-06	195	83	6	6687e579582d7a239bee80846de0cf827a6f6a62
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_D3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PCNX2 CD44 PGBD1 PARD3B SAMD4A	9.07e-06	150	83	5	580ed7733857402345f43ca2623f72cdd1edf22c
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	WWC2 RBPMS ZNF608 PIP5K1B PARD3B	1.81e-05	173	83	5	b799c06a6a5754668e789f70c0c8bc1508568575
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	OAS2 PIP5K1B EVI2B PARP14 TARBP1	1.91e-05	175	83	5	97616bb5c127284aa9e67bc336dfcf29e137164b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 FAT1 RBPMS PPFIBP1 PFKFB3	1.96e-05	176	83	5	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	WWC2 RBPMS ZNF608 PIP5K1B PARD3B	2.13e-05	179	83	5	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	droplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2IP ZNF608 PPFIBP1 MCC LUZP1	2.25e-05	181	83	5	92d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 FAT1 RBPMS PPFIBP1 JHY	2.25e-05	181	83	5	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 ZNF608 TRPS1 NSD1 EIF4G3	2.31e-05	182	83	5	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL5A1 FAT1 TRPS1 PFKFB3 SAMD4A	2.31e-05	182	83	5	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 ZNF608 TRPS1 NSD1 EIF4G3	2.49e-05	185	83	5	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	EDARADD PIP5K1B PARD3B EXTL3 SPATS2	2.56e-05	186	83	5	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	EDARADD PIP5K1B PARD3B EXTL3 SPATS2	2.56e-05	186	83	5	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	critical-Myeloid-Monocyte-derived_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ASAP3 OAS2 PARP14 HESX1 SAMD4A	2.62e-05	187	83	5	72e4aec49ea0c5fe6cee2a1a46369dbc90cd3fad
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 FAT1 RBPMS PPFIBP1 PFKFB3	2.76e-05	189	83	5	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 RBPMS PPFIBP1 PARD3B PFKFB3	2.90e-05	191	83	5	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 RBPMS ZNF608 PPFIBP1 SAMD4A	2.90e-05	191	83	5	1cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT1 ZNF608 MCC PIP5K1B ADCYAP1R1	2.98e-05	192	83	5	67d6230e32d446dcb12047fae2c3f1faa80dd720
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	CEP350 ZFYVE16 AVL9 RO60 MGA	3.05e-05	193	83	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 FAT1 RBPMS PPFIBP1 PFKFB3	3.05e-05	193	83	5	0f2167eef8203a5659c8c72e4e77646003d64797
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2IP COL5A1 NSD1 PFKFB3 LUZP1	3.13e-05	194	83	5	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	DAB2IP ZNF608 TRAK2 PARP14 SAMD4A	3.13e-05	194	83	5	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	DAB2IP ZNF608 TRAK2 PARP14 SAMD4A	3.13e-05	194	83	5	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT1 ZNF608 MCC ADCYAP1R1 SAMD4A	3.29e-05	196	83	5	7af6c5147ac859353504d19727dbe24f63a29dd4
ToppCell	COPD-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	TRPS1 CD44 AP3M2 PFKFB3 LUZP1	3.29e-05	196	83	5	c9bdd505c3ab380ed7b272aa518df31a0a706a06
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PIEZO2 EDARADD PIP5K1B B3GAT2	1.06e-04	131	83	4	9ca209a8652aae603c4a867ea06b06ac51e7d189
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TAF7L ZNF805 PARD3B TDRD1	1.73e-04	149	83	4	4b44108c40376a6b73258df40d2424e68f991383
ToppCell	356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PPFIBP1 EDARADD CD44 PFKFB3	1.97e-04	154	83	4	692eb053620db86d301b09bf743ab45fccc245be
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NBAS TAF7L ZNF805 AP3M2	1.97e-04	154	83	4	ec920cae12ea1d14b6c973f6e903f895f80e3c50
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DAB2IP ZNF608 PIP5K1B SPATS2	2.02e-04	155	83	4	881422c57d230c0e2e5f9098ab888caa94ca61aa
ToppCell	LPS-antiTNF-Endothelial-Mes-Like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCNX2 RAVER2 AP3M2 EVI2B	2.17e-04	158	83	4	50df52d64d07178975563abd98ce4fddb9f2f7ef
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 MCF2L2 PIP5K1B NOTCH3	2.22e-04	159	83	4	5ca96db4281abb5f646150ccf36adc66ab201c78
ToppCell	facs-Brain_Myeloid-Cerebellum_\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPS1 OAS2 EVI2B PARP14	2.33e-04	161	83	4	5c762609531a7c5505aa5637abf8e0311568d7fd
ToppCell	facs-Brain_Myeloid-Cerebellum_-18m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPS1 OAS2 EVI2B PARP14	2.33e-04	161	83	4	b14a83ad07a7acb07c766aa862b527698976b6fc
ToppCell	facs-Brain_Myeloid-Cerebellum_-18m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPS1 OAS2 EVI2B PARP14	2.33e-04	161	83	4	c5d9d47dcedfbb1ac77f4afaf860ae4d9f26fd3f
ToppCell	facs-Brain_Myeloid-Cerebellum_-18m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPS1 OAS2 EVI2B PARP14	2.33e-04	161	83	4	26c0d876339bfd34d9a43af5b9fb08f50526f2c9
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-Plasma_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DAB2IP ZNF608 PIP5K1B SPATS2	2.39e-04	162	83	4	8278dccdb139396ede34b83b02ebce837f2489d6
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFYVE16 GEMIN5 RO60 FHDC1	2.44e-04	163	83	4	132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_D3\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	PCNX2 CD44 PARD3B SAMD4A	2.56e-04	165	83	4	a379fa981db51bec01adea7b1e55e133e15ec383
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 TAF7L PIP5K1B ZNF543	2.56e-04	165	83	4	e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 TAF7L PIP5K1B ZNF543	2.56e-04	165	83	4	b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 TAF7L PIP5K1B ZNF543	2.56e-04	165	83	4	d8f8b088fd28a6b9dbd6b51bcaee42000e963321
ToppCell	LV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	GARIN3 RBPMS PIP5K1B NOTCH3	2.56e-04	165	83	4	f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCell	LPS-antiTNF-Endothelial-Mes-Like-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCNX2 MCPH1 RAVER2 EVI2B	2.62e-04	166	83	4	3b750d4023a0a09d86113aae5a97d84391f7b482
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	COL5A1 CCSER2 AP3M2 PRKN	2.68e-04	167	83	4	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DAB2IP ZNF608 PARP14 SAMD4A	2.80e-04	169	83	4	665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DAB2IP ZNF608 PARP14 SAMD4A	2.80e-04	169	83	4	6614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF608 ZFYVE16 MCC PFKFB3	2.87e-04	170	83	4	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	WWC2 RBPMS ZNF608 PIP5K1B	2.87e-04	170	83	4	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INTS2 CD44 PGBD1 GEMIN5	2.87e-04	170	83	4	45de83a2231208b8e1f21061d0b91644b4a3ba93
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	WWC2 PPFIBP1 PARD3B SAMD4A	2.87e-04	170	83	4	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	FAM193A OAS2 EIF4G3 PARP14	2.87e-04	170	83	4	07b561cd9c528bc8444c9385e1de621eee7b697e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 MCF2L2 PIP5K1B NOTCH3	2.87e-04	170	83	4	876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 MCF2L2 PIP5K1B NOTCH3	2.87e-04	170	83	4	1f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCell	356C-Myeloid-Monocyte-CD16+_Monocyte\|Monocyte / Donor, Lineage, Cell class and subclass (all cells)	PPP1R26 INTS2 PPFIBP1 TARBP1	3.00e-04	172	83	4	9dca1542145d88559527db7e0f6ad150df59ca2d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FAM193A GEMIN5 EXTL3 EIF4G3	3.06e-04	173	83	4	5295ed31648abf8edff214cf67cd4769f20f9e6d
ToppCell	COVID-19-kidney-REN+Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RBPMS PIEZO2 PIP5K1B NOTCH3	3.13e-04	174	83	4	8393f0b43c767839c1630bcb952d62b42efc788d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 TAF7L ZNF805 NOTCH3	3.20e-04	175	83	4	12f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIEZO2 PPFIBP1 EDARADD FHDC1	3.20e-04	175	83	4	f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCell	pdx-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	PIP5K1B PARD3B PRKN SAMD4A	3.27e-04	176	83	4	1e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|normal_Lymph_Node / Location, Cell class and cell subclass	PDSS2 ZCCHC8 PPFIBP1 PFKFB3	3.27e-04	176	83	4	476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCell	droplet-Kidney-nan-18m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R26 PFKFB3 SPATS2 ARMCX4	3.27e-04	176	83	4	533d544852038c0612aacf87f4b1c88ff7aace82
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2IP PFKFB3 PARP14 LUZP1	3.34e-04	177	83	4	ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2IP PFKFB3 PARP14 LUZP1	3.34e-04	177	83	4	f471f7747d6e8db7546899019af9508f48a14f89
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2IP PFKFB3 PARP14 LUZP1	3.34e-04	177	83	4	cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MCPH1 PRKN ARMCX4 TARBP1	3.34e-04	177	83	4	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2IP NSD1 PARP14 LUZP1	3.41e-04	178	83	4	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EDARADD RTN4 ADAM2 MCCD1	3.41e-04	178	83	4	f1cfc348d51362eb8c92c625f21f682afc0352b7
ToppCell	COVID-19-Heart-VSMC\|Heart / Disease (COVID-19 only), tissue and cell type	FAT1 RBPMS PIP5K1B NOTCH3	3.48e-04	179	83	4	a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT1 RBPMS ZNF608 NOTCH3	3.56e-04	180	83	4	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	normal_Pleural_Fluid-Myeloid_cells-CD1c+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	COL5A1 PPFIBP1 PARD3B SPATS2	3.63e-04	181	83	4	cc7ae1221a28bc404138a7efee0ad08a19cc3d86
ToppCell	droplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2IP ZNF608 PPFIBP1 MCC	3.71e-04	182	83	4	81279877b920b5a1bc991a07d3031d6458700fe3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 RBPMS PPFIBP1 PFKFB3	3.79e-04	183	83	4	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	CEP350 OAS2 PARP14 ZNF292	3.79e-04	183	83	4	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	mild-B_cell\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PPP1R26 EDARADD PGBD1 MCC	3.79e-04	183	83	4	175aaf8fbbff52eab87d78a49d5ab02cd489c438
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 RBPMS PPFIBP1 PFKFB3	3.79e-04	183	83	4	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	CV-Healthy-7\|CV / Virus stimulation, Condition and Cluster	ZNF805 ARMCX4 B3GAT2 JHY	3.87e-04	184	83	4	0e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 ZNF608 NSD1 EIF4G3	3.87e-04	184	83	4	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D122\|Adult / Lineage, Cell type, age group and donor	WWC2 PPFIBP1 PARD3B SAMD4A	3.87e-04	184	83	4	561592edc3083fad41b91811151b442207c65dd9
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DAB2IP AP3M2 ADCYAP1R1 NOTCH3	3.95e-04	185	83	4	a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	WWC2 RBPMS PARD3B SAMD4A	3.95e-04	185	83	4	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	NBAS KMT2D AVL9 ZNF292	3.95e-04	185	83	4	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	PIP5K1B PARD3B PRKN SAMD4A	3.95e-04	185	83	4	1d874608aa2062024323512f68889219471b2f00
ToppCell	CV-Healthy-7\|Healthy / Virus stimulation, Condition and Cluster	ZNF805 ARMCX4 B3GAT2 JHY	3.95e-04	185	83	4	1979d189c204f4c2893e3170a514ee7d5523406c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT1 ZNF608 PIP5K1B PARD3B	4.03e-04	186	83	4	77592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 RBPMS PPFIBP1 SAMD4A	4.03e-04	186	83	4	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2IP CEP350 ZNF608 NSD1	4.03e-04	186	83	4	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	CEP350 CCSER2 PARD3B LUZP1	4.03e-04	186	83	4	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	FAT1 RBPMS ZNF608 NOTCH3	4.11e-04	187	83	4	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 RBPMS PPFIBP1 SAMD4A	4.11e-04	187	83	4	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 MCF2L2 PIP5K1B NOTCH3	4.11e-04	187	83	4	15d6e158562d7d85af3ceaf955439b379c8fce81
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 MCF2L2 PIP5K1B NOTCH3	4.11e-04	187	83	4	f62074b631fd45ad299c69d71b09267b04d656ee
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	WWC2 PPFIBP1 PARD3B SAMD4A	4.11e-04	187	83	4	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DAB2IP AP3M2 ADCYAP1R1 NOTCH3	4.11e-04	187	83	4	a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 MCF2L2 PIP5K1B NOTCH3	4.19e-04	188	83	4	32f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCell	3'-Adult-Distal_Rectal-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RBPMS TRPS1 NOTCH3 MYLK2	4.28e-04	189	83	4	d69b7a01dd4d6ad043bb6210e9ab34b49578389c
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	PPFIBP1 PIP5K1B PRKN SAMD4A	4.28e-04	189	83	4	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	tumor_Lung-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	RBPMS PIP5K1B ADCYAP1R1 NOTCH3	4.28e-04	189	83	4	9c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	RBPMS PARD3B PRKN PFKFB3	4.28e-04	189	83	4	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	3'-Adult-Distal_Rectal-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RBPMS TRPS1 NOTCH3 MYLK2	4.28e-04	189	83	4	2b5f1b4f173a224342ea4f10b193ee33b7662699
Disease	breast ductal carcinoma (is_implicated_in)	CD44 RICTOR	2.23e-05	3	81	2	DOID:3007 (is_implicated_in)
Disease	esophagus squamous cell carcinoma (is_marker_for)	DAB2IP FAT1 KMT2D RICTOR	5.24e-05	74	81	4	DOID:3748 (is_marker_for)
Disease	lung small cell carcinoma (is_implicated_in)	FAT1 KMT2D RICTOR	6.21e-05	28	81	3	DOID:5409 (is_implicated_in)
Disease	Adenoid Cystic Carcinoma	FAT1 NSD1 MARK2 MGA	1.69e-04	100	81	4	C0010606
Disease	microcephaly (is_implicated_in)	MCPH1 NSD1	2.06e-04	8	81	2	DOID:10907 (is_implicated_in)
Disease	Intellectual Disability	PUF60 ZCCHC8 MCC NSD1 KDM3B LARP7 ZNF292	2.31e-04	447	81	7	C3714756
Disease	esophagus squamous cell carcinoma (is_implicated_in)	FAT1 KMT2D RICTOR	2.60e-04	45	81	3	DOID:3748 (is_implicated_in)
Disease	vitamin B6 measurement	ZNF608 ADCYAP1R1	3.30e-04	10	81	2	EFO_0004621
Disease	gastric adenocarcinoma (is_implicated_in)	KMT2D CD44	4.03e-04	11	81	2	DOID:3717 (is_implicated_in)
Disease	unipolar depression	NBAS FAT1 PIEZO2 ZNF608 FIG4 RTN4 TRPS1 PGBD1 MCC EIF4G3 ADCYAP1R1	4.48e-04	1206	81	11	EFO_0003761
Disease	Mental Retardation, Psychosocial	ZCCHC8 MCC NSD1 LARP7	5.92e-04	139	81	4	C0025363
Disease	Profound Mental Retardation	ZCCHC8 MCC NSD1 LARP7	5.92e-04	139	81	4	C0020796
Disease	Mental deficiency	ZCCHC8 MCC NSD1 LARP7	5.92e-04	139	81	4	C0917816
Disease	neurodegenerative disease (implicated_via_orthology)	MTMR12 FIG4 TRAK2 MARK2	6.94e-04	145	81	4	DOID:1289 (implicated_via_orthology)
Disease	Lung Neoplasms	DAB2IP PRKN RICTOR NOTCH3 SLC3A2	8.27e-04	265	81	5	C0024121
Disease	Malignant neoplasm of lung	DAB2IP PRKN RICTOR NOTCH3 SLC3A2	8.41e-04	266	81	5	C0242379
Disease	T-Cell Lymphoma	KMT2D MGA	8.71e-04	16	81	2	C0079772
Disease	Polyposis, Adenomatous Intestinal	CD44 MCC	8.71e-04	16	81	2	C2713442
Disease	Familial Intestinal Polyposis	CD44 MCC	8.71e-04	16	81	2	C2713443
Disease	colorectal cancer (is_marker_for)	DAB2IP ASAP3 KDM3B RICTOR	9.34e-04	157	81	4	DOID:9256 (is_marker_for)
Disease	Adenomatous Polyposis Coli	CD44 MCC	9.85e-04	17	81	2	C0032580
Disease	age at onset, Parkinson disease	TRPS1 PRKN	1.11e-03	18	81	2	EFO_0004847, MONDO_0005180
Disease	Glioblastoma	FAT1 PRKN NOTCH3	1.36e-03	79	81	3	C0017636
Disease	fetal hemoglobin measurement	MCC B3GAT2	1.51e-03	21	81	2	EFO_0004576
Disease	Giant Cell Glioblastoma	FAT1 PRKN NOTCH3	1.62e-03	84	81	3	C0334588
Disease	Carcinoma of lung	PRKN RICTOR	1.81e-03	23	81	2	C0684249
Disease	body surface area	WWC2 MCPH1 ZNF608 TRPS1 NSD1 SPATA31C1 LUZP1	1.95e-03	643	81	7	EFO_0022196
Disease	Dwarfism	KDM3B LARP7	2.14e-03	25	81	2	C0013336
Disease	response to peginterferon alfa-2a	NBAS PRKN	2.14e-03	25	81	2	EFO_0010103
Disease	Squamous cell carcinoma of esophagus	FAT1 KMT2D NOTCH3	2.30e-03	95	81	3	C0279626

Protein segments in the cluster

Peptide	Gene	Start	Entry
QSDPEDVGKMTTENN	TDRD1	461	Q9BXT4
GESQMKQGPDFLQSL	ASAP3	201	Q8TDY4
SGTGIMKPLDQDFQN	ADAM2	76	Q99965
LQSSDGPLKDMQFGN	PDSS2	171	Q86YH6
NGGGENMALKDESPQ	FAM193A	331	P78312
QSQAVTKIQGDDMPG	ARMCX4	281	Q5H9R4
NTQEKQPATVGMAEG	RAVER2	506	Q9HCJ3
MNNGGKAEKENTPSE	RBPMS	1	Q93062
NGKGPELDSVMNSEN	NSD1	1131	Q96L73
GTMSLQAGASKPDEN	AP3M2	356	P53677
EANEPDLQMANGGKS	DAB2IP	731	Q5VWQ8
LDMSEPQTKGTGENS	FAT1	4496	Q14517
SDKENGNIATAPGFM	FHDC1	11	Q9C0D6
SAPQGNSELEDMENK	PARD3B	816	Q8TEW8
NMETSTEEKENLPGG	MCPH1	591	Q8NEM0
SQETSMELSGGKGEQ	JHY	166	Q6NUN7
MGSPGKEENENRDLT	NEDD1	466	Q8NHV4
PKASMEEQTSSRGNG	MCCD1	36	P59942
TGNDQEGRESKVMPT	MGA	3031	Q8IWI9
SPHQKDTNMGREGQD	MTMR12	496	Q9C0I1
DTNMGREGQDTQSKP	MTMR12	501	Q9C0I1
GQDTSMDDNPFGTRK	PPFIBP1	506	Q86W92
NPGTTQMKDNFDIGE	GPR158	991	Q5T848
KDQGNPQFEMSTSKG	MCF2L2	961	Q86YR7
SDLEAKEGQMPNESN	PCNX2	561	A6NKB5
TPGQAGQAKMQGDTS	MYLK2	211	Q9H1R3
MSSAAENGEAAPGKQ	PIP5K1B	1	O14986
DLEGQESNQSDKPTM	EVI2B	346	P34910
QLPGQNMKGSRSSAD	PFKFB3	501	Q16875
TTSAPNKGMEEGEDN	INTS2	971	Q9H0H0
NGANKDMQDSKEETP	NOTCH3	1961	Q9UM47
MSPSLQEGAQLGENK	HESX1	1	Q9UBX0
LMDNSAPQSEGGTLK	KDM3B	251	Q7LBC6
ETDSGVPQNTGMKNE	LARP7	416	Q4G0J3
MGNGESQLSSVPAQK	OAS2	1	P29728
QEQDGIFKMSLSPDG	NBAS	316	A2RRP1
ASSGMKPERSLQNNG	RICTOR	636	Q6R327
LVQKLQSPDMGGNES	ADCYAP1R1	331	P41586
QENEVMKEGGSPAGQ	PARP14	776	Q460N5
SGTMTVDGNKNSPAD	CCSER2	331	Q9H7U1
PGDQSGDENITQMLK	MCC	486	P23508
PSGLNGEASKSQEMV	CD44	696	P16070
DVMKPQDSGSSANEQ	ELOB	101	Q15370
QASQGIMQPLGKEDS	FIG4	881	Q92562
RSGKAAGTDPNMADN	EXTL3	556	O43909
PRKSMSEDGGLQESN	AVL9	241	Q8NBF6
GSQPGMQESDFLKQI	B3GAT2	266	Q9NPZ5
TAKELNMPFSGGQDS	CEP350	1661	Q5VT06
NMTVKGQSEDPGSLL	SLC3A2	506	P08195
DAGSKGPMVSAQESQ	COL5A1	531	P20908
NTMELPDTNGAGVKS	LUZP1	726	Q86V48
QASIQNGKDSLTMPG	MARK2	496	Q7KZI7
RNSDMKNQGEENGFP	EDARADD	66	Q8WWZ3
MSGQVGDLSPSQEKS	SEC14L6	1	B5MCN3
DPNQGGKDITEEIMS	EIF4G3	146	O43432
DENKVDGMNAPKGQT	EIF4B	526	P23588
PGENESSKSMAGAAN	GARIN3	321	Q8TC56
NMDLKEQPGNTISAG	RTN4	206	Q9NQC3
QAPENFQEGKDMSES	TAF7L	76	Q5H9L4
KGQEMNATGGDDPRN	PRKN	76	O60260
PQGTDSIKMENGQST	PUF60	36	Q9UHX1
PGDTRMSQGQGKTDE	PPP1R26	656	Q5T8A7
EEMEQSGEASGKPNR	PGBD1	276	Q96JS3
MQLQDELPGTSQAKG	SPATA31C1	476	P0DKV0
GKMTANSVLEPGNSE	RO60	286	P10155
GQGEKSMLQPQDIET	MSANTD4	281	Q8NCY6
SEEVAGSSQKMGQPG	TRAK2	461	O60296
MSPKATEETGQAQSG	TRPS1	156	Q9UHF7
QEEQSAPSSEKGGMN	SPATS2	116	Q86XZ4
QKNESNSAGSPADME	ZCCHC8	431	Q6NZY4
SVPEMNEDGNRKESN	WWC2	931	Q6AWC2
MKENSGPVENGVSDQ	GEMIN5	766	Q8TEQ6
LTQEPGEGQDMQKLS	PIEZO2	1501	Q9H5I5
QEESKETSMNGLSGG	ZNF292	486	O60281
NTGKECGDENSSPQM	USP29	396	Q9HBJ7
SQLGQSKDQDGPSEM	ZNF543	116	Q08ER8
MELDLNSSSEDNKPG	ZNF608	506	Q9ULD9
VSENENNIMNPKGDS	ZNF227	146	Q86WZ6
LQEMDSGQEPTVGSQ	TARBP1	791	Q13395
DNEGQLKTNKPMAGS	TCHHL1	201	Q5QJ38
NTFQEEGSGMKDVPA	SAMD4A	316	Q9UPU9
QLGQPKDQDGFSEMQ	ZNF805	121	Q5CZA5
SVEKLSMNTGNEGLP	ZFYVE16	946	Q7Z3T8
DPGMSGLSQTELEKQ	KMT2D	2666	O14686