Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal protein binding	KIF21B RAB11B SPATA6L MYO9A SPTBN2 RAB11A OBSCN EPB41L5 C10orf90 DBN1 PPP2CA PPP2CB LLGL2 SYNE3 DST NKD2 SMC3 AFDN HOOK2 SNTB2 DMTN KIF11	1.61e-05	1099	146	22	GO:0008092
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RAP1GDS1 TRIO KALRN MYO9A DOCK8 OBSCN ARHGAP35 ARHGAP22 LLGL2 ARHGAP31 SRGAP3 RALGPS1	3.57e-04	507	146	12	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RAP1GDS1 TRIO KALRN MYO9A DOCK8 OBSCN ARHGAP35 ARHGAP22 LLGL2 ARHGAP31 SRGAP3 RALGPS1	3.57e-04	507	146	12	GO:0030695
GeneOntologyMolecularFunction	myosin binding	RAB11B SPATA6L RAB11A LLGL2 NKD2	4.00e-04	85	146	5	GO:0017022
GeneOntologyBiologicalProcess	regulation of small GTPase mediated signal transduction	TRIO KALRN MYO9A DOCK8 OBSCN ARHGAP35 ARHGAP22 PPP2CB ARHGAP31 SRGAP3 RALGPS1 RIPOR1	3.97e-06	333	144	12	GO:0051056
Domain	Spectrin	TRIO KALRN SPTBN2 SYNE3 DST	8.76e-07	23	148	5	PF00435
Domain	Spectrin_repeat	TRIO KALRN SPTBN2 SYNE3 DST	2.97e-06	29	148	5	IPR002017
Domain	SPEC	TRIO KALRN SPTBN2 SYNE3 DST	4.95e-06	32	148	5	SM00150
Domain	Spectrin/alpha-actinin	TRIO KALRN SPTBN2 SYNE3 DST	4.95e-06	32	148	5	IPR018159
Domain	RhoGAP	MYO9A ARHGAP35 ARHGAP22 ARHGAP31 SRGAP3	1.31e-04	62	148	5	SM00324
Domain	PP2Ac	PPP2CA PPP2CB PPP3CB	1.32e-04	13	148	3	SM00156
Domain	Ser/Thr-sp_prot-phosphatase	PPP2CA PPP2CB PPP3CB	1.32e-04	13	148	3	IPR006186
Domain	SER_THR_PHOSPHATASE	PPP2CA PPP2CB PPP3CB	1.32e-04	13	148	3	PS00125
Domain	RhoGAP	MYO9A ARHGAP35 ARHGAP22 ARHGAP31 SRGAP3	1.42e-04	63	148	5	PF00620
Domain	RhoGAP_dom	MYO9A ARHGAP35 ARHGAP22 ARHGAP31 SRGAP3	1.53e-04	64	148	5	IPR000198
Domain	RHOGAP	MYO9A ARHGAP35 ARHGAP22 ARHGAP31 SRGAP3	1.53e-04	64	148	5	PS50238
Domain	-	MYO9A ARHGAP35 ARHGAP22 ARHGAP31 SRGAP3	1.53e-04	64	148	5	1.10.555.10
Domain	P-loop_NTPase	KIF21B GTPBP4 RAB11B NWD1 SPG7 MYO9A ATAD5 RAB11A MCM6 ARHGAP35 SMC3 IGHMBP2 CHD6 CHST2 SNRNP200 KIF11 NLRP13	4.04e-04	848	148	17	IPR027417
Domain	Rho_GTPase_activation_prot	MYO9A ARHGAP35 ARHGAP22 ARHGAP31 SRGAP3	6.74e-04	88	148	5	IPR008936
Pathway	REACTOME_RAC1_GTPASE_CYCLE	TRIO KALRN DOCK8 ARHGAP35 ARHGAP22 TAOK3 ARHGAP31 SRGAP3	5.51e-05	175	107	8	MM15599
Pathway	REACTOME_RAC1_GTPASE_CYCLE	TRIO KALRN DOCK8 ARHGAP35 ARHGAP22 TAOK3 ARHGAP31 SRGAP3	7.84e-05	184	107	8	M41809
Pathway	REACTOME_CDC42_GTPASE_CYCLE	TRIO DOCK8 ARHGAP35 ARHGAP22 ARHGAP31 SRGAP3	7.87e-05	94	107	6	MM15598
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	RAP1GDS1 H2AZ2 TRIO KALRN MYO9A DOCK8 OBSCN DBN1 ARHGAP35 ARHGAP22 PPP2CA PPP2CB TAOK3 DST ARHGAP31 SRGAP3	1.01e-04	720	107	16	M41838
Pathway	REACTOME_RHOA_GTPASE_CYCLE	TRIO KALRN MYO9A OBSCN ARHGAP35 ARHGAP22 ARHGAP31	1.02e-04	142	107	7	MM15576
Pathway	REACTOME_RHOA_GTPASE_CYCLE	TRIO KALRN MYO9A OBSCN ARHGAP35 ARHGAP22 ARHGAP31	1.38e-04	149	107	7	M41805
Pathway	REACTOME_RHO_GTPASE_CYCLE	TRIO KALRN MYO9A DOCK8 OBSCN DBN1 ARHGAP35 ARHGAP22 TAOK3 DST ARHGAP31 SRGAP3	1.54e-04	450	107	12	M27078
Pathway	REACTOME_RHOJ_GTPASE_CYCLE	TRIO DOCK8 ARHGAP35	2.22e-04	16	107	3	MM15605
Pathway	REACTOME_CELL_JUNCTION_ORGANIZATION	PARD6G TESK1 DST AFDN CDH10	2.29e-04	73	107	5	MM15126
Pathway	REACTOME_CELL_JUNCTION_ORGANIZATION	PARD6G TESK1 HEYL DST AFDN CDH10	2.63e-04	117	107	6	M19248
Pathway	REACTOME_RHO_GTPASE_CYCLE	TRIO KALRN MYO9A DOCK8 OBSCN ARHGAP35 ARHGAP22 TAOK3 DST ARHGAP31 SRGAP3	4.97e-04	439	107	11	MM15595
Pathway	KEGG_TIGHT_JUNCTION	PARD6G PPP2CA PPP2CB LLGL2 AFDN SYMPK	5.02e-04	132	107	6	M11355
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SETD1A MAN2A2 SPG7 TRIO KALRN FNTB SPEG OBSCN LAMB2 UBL4A HUWE1 REV3L ARHGAP35 TESK1 MST1R PPP2CB HEYL INTS5 LLGL2 SYNE3 DST NAPRT RALGPS1 ZER1 RIPOR1 SNAPC4 IGSF3 PCNT SYMPK	5.12e-15	1105	150	29	35748872
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TLK2 KIF21B GTPBP4 TRIO KALRN SPTBN2 DDN DIDO1 DBN1 HUWE1 IPO4 PPP2CB CCDC124 DST PPP3CB SRGAP3 DCHS1 AFDN CDH10 KIF11 PCNT	1.21e-09	963	150	21	28671696
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	USP30 H2AZ2 ATAD5 RAB11A EPB41L5 LAMB2 DIDO1 IPO4 GGCX XAB2 HMG20B PPP2CA INTS5 NOP14 CCDC124 DST INTS2 IGHMBP2 NFRKB ALDH18A1 AFDN CHD6 TFB2M SNTB2	2.88e-08	1497	150	24	31527615
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	TLK2 KIF21B SPNS1 PRELID1 UBL4A MCM6 C10orf90 XAB2 RTF1 BMP1 PPP2CA MTRF1 LLGL2 INTS2 SMC3 CLEC14A NFRKB VSIG10L H2AZ1 ALDH18A1 C9orf50 PCNT	6.53e-08	1327	150	22	32694731
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SETD1A SPTBN2 DIDO1 DBN1 HUWE1 ARHGAP35 JMJD1C MTRF1 RBM25 ZZZ3 NFRKB AFDN SNRNP200 SYMPK	1.27e-07	549	150	14	38280479
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	GTPBP4 SPTBN2 DIDO1 MCM6 HUWE1 IPO4 XAB2 RBM25 NOP14 DST ALDH18A1 AFDN SNRNP200 PCNT SYMPK	1.70e-07	653	150	15	22586326
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	GTPBP4 SETD1A SPNS1 DIDO1 MCM6 HUWE1 IPO4 TERT XAB2 ORC2 PPP2CA TAOK3 RBM25 NOP14 SMC3 NFRKB H2AZ1 ALDH18A1 CHD6 SNRNP200	1.09e-06	1318	150	20	30463901
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	TLK2 GTPBP4 H2AZ2 DIDO1 MCM6 HUWE1 IPO4 JMJD1C XAB2 RTF1 RBM25 NOP14 SMC3 ANP32A ALDH18A1 SNRNP200 SYMPK	1.42e-06	989	150	17	36424410
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	PRELID1 MYO9A XBP1 C10orf90 IPO4 CCDC167 PPP2CB DST SMC3 HDAC10	1.50e-06	322	150	10	26514267
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	KIF21B SETD1A USP30 MYO9A XBP1 C10orf90 DBN1 JMJD1C RTF1 ARHGAP22 ZZZ3 INTS2 SMC3 ALDH18A1 KCNIP4 INAVA SNAPC4 DOP1B SYMPK	1.84e-06	1242	150	19	30973865
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	GTPBP4 SPTBN2 DIDO1 DBN1 IPO4 XAB2 PPP2CB RBM25 NOP14 DST PPP3CB SMC3 H2AZ1 ALDH18A1 TFB2M SNRNP200 SNTB2 DMTN KIF11	2.19e-06	1257	150	19	36526897
Pubmed	Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.	MCM6 REV3L FAN1 PPP2CA PPP3CB SMC3	2.20e-06	87	150	6	17148452
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	TRIO MYO9A DOCK8 UBL4A MCM6 HUWE1 ARHGAP35 ARHGAP22 PPP2CA RBM25 SMC3 ARHGAP31 SRGAP3 ANP32A ALDH18A1 SNTB2	2.41e-06	916	150	16	32203420
Pubmed	The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer.	PPP2CA PPP2CB INTS5 INTS2	3.92e-06	25	150	4	34004147
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	GTPBP4 SPNS1 KALRN RNPC3 SPTBN2 DIDO1 DBN1 ARHGAP35 XAB2 INTS5 RBM25 NOP14 CCDC124 DST CHD6 SNRNP200 SYMPK	4.71e-06	1082	150	17	38697112
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	RAP1GDS1 H2AZ2 FNTB LAMB2 MCM6 HUWE1 IPO4 RTF1 PPP2CA PPP2CB CCDC124 PPP3CB ASB6 NAPRT SURF2 ANP32A NFRKB H2AZ1 RIPOR1 SNRNP200	4.83e-06	1455	150	20	22863883
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ARHGAP35 RTF1 DST SRGAP3 CHD6 SNRNP200 DOP1B PCNT	6.48e-06	225	150	8	12168954
Pubmed	A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.	HUWE1 TAOK3 SMC3	9.23e-06	10	150	3	17478428
Pubmed	A human MAP kinase interactome.	ZNF142 RAP1GDS1 MYO9A SPTBN2 LAMB2 DST SMC3 ARHGAP31 CHD6 SNRNP200 HERPUD1	9.23e-06	486	150	11	20936779
Pubmed	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	MYO9A C10orf90 ADAM12 CLEC14A AFDN	9.36e-06	65	150	5	23319000
Pubmed	Rab11a Is Essential for the Development and Integrity of the Stereocilia and Kinocilia in the Mammalian Organ of Corti.	RAB11B SPTBN2 RAB11A	1.26e-05	11	150	3	37225424
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	GTPBP4 DBN1 ARHGAP35 XAB2 RTF1 ORC2 RBM25 ZZZ3 DST H2AZ1 SNRNP200	1.34e-05	506	150	11	30890647
Pubmed	A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.	GTPBP4 ADAM12 JMJD1C ITIH5 BTBD16 ARHGAP22 SMC3 PRF1 ALDH18A1 KIF11	1.39e-05	415	150	10	16385451
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	H2AZ2 ATAD5 DIDO1 DBN1 JMJD1C XAB2 ORC2 RBM25 ZZZ3 CCDC124 NFRKB H2AZ1 AFDN SNRNP200 SYMPK	1.75e-05	954	150	15	36373674
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	GTPBP4 DIDO1 MCM6 JMJD1C XAB2 PPP3CB ANP32A NFRKB SNRNP200	1.78e-05	339	150	9	30415952
Pubmed	Activation of SV40 DNA replication in vitro by cellular protein phosphatase 2A.	PPP2CA PPP2CB	1.85e-05	2	150	2	2555176
Pubmed	Hypercoagulability evaluation in congenital red blood cell disorders using thrombin generation assay.	HEYL NOTCH3	1.85e-05	2	150	2	37024320
Pubmed	Regulation of spindle formation by active mitogen-activated protein kinase and protein phosphatase 2A during mouse oocyte meiosis.	PPP2CA PPP2CB	1.85e-05	2	150	2	11751260
Pubmed	Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes.	SHH DIO3	1.85e-05	2	150	2	17720805
Pubmed	Protein phosphatase 2A (PP2A) has a potential role in CAPE-induced apoptosis of CCRF-CEM cells via effecting human telomerase reverse transcriptase activity.	TERT PPP2CA	1.85e-05	2	150	2	17852432
Pubmed	Kinesin Family of Proteins Kif11 and Kif21B Act as Inhibitory Constraints of Excitatory Synaptic Transmission Through Distinct Mechanisms.	KIF21B KIF11	1.85e-05	2	150	2	30479371
Pubmed	A role for Rab11 in the homeostasis of the endosome-lysosomal pathway.	RAB11B RAB11A	1.85e-05	2	150	2	30981667
Pubmed	Serine/threonine-protein phosphatase 2A physically interacts with human telomerase reverse transcriptase hTERT and regulates its subcellular distribution.	TERT PPP2CA	1.85e-05	2	150	2	22961627
Pubmed	Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP.	TRIO KALRN	1.85e-05	2	150	2	26858404
Pubmed	Regional expression of protein phosphatase type 1 and 2A catalytic subunit isoforms in the human heart.	PPP2CA PPP2CB	1.85e-05	2	150	2	11113010
Pubmed	H2A.Z facilitates licensing and activation of early replication origins.	H2AZ2 H2AZ1	1.85e-05	2	150	2	31875854
Pubmed	Histone H2A.Z is required for androgen receptor-mediated effects on fear memory.	H2AZ2 H2AZ1	1.85e-05	2	150	2	32916283
Pubmed	Orthologous relationship of obscurin and Unc-89: phylogeny of a novel family of tandem myosin light chain kinases.	SPEG OBSCN	1.85e-05	2	150	2	15185077
Pubmed	The role of protein phosphatase 2A catalytic subunit Calpha in embryogenesis: evidence from sequence analysis and localization studies.	PPP2CA PPP2CB	1.85e-05	2	150	2	10543450
Pubmed	Dystonin/Bpag1 is a necessary endoplasmic reticulum/nuclear envelope protein in sensory neurons.	SYNE3 DST	1.85e-05	2	150	2	18638474
Pubmed	Protein phosphatase 2A in the healthy and failing heart: New insights and therapeutic opportunities.	PPP2CA PPP2CB	1.85e-05	2	150	2	34902541
Pubmed	Human liver phosphatase 2A: cDNA and amino acid sequence of two catalytic subunit isotypes.	PPP2CA PPP2CB	1.85e-05	2	150	2	2837763
Pubmed	Structure and transcriptional regulation of protein phosphatase 2A catalytic subunit genes.	PPP2CA PPP2CB	1.85e-05	2	150	2	1846293
Pubmed	The NOTCH3 Downstream Target HEYL Is Required for Efficient Human Airway Basal Cell Differentiation.	HEYL NOTCH3	1.85e-05	2	150	2	34831437
Pubmed	H2A.Z is dispensable for both basal and activated transcription in post-mitotic mouse muscles.	H2AZ2 H2AZ1	1.85e-05	2	150	2	32266374
Pubmed	PP2A regulates kinetochore-microtubule attachment during meiosis I in oocyte.	PPP2CA PPP2CB	1.85e-05	2	150	2	27096707
Pubmed	Sex-specific effects of the histone variant H2A.Z on fear memory, stress-enhanced fear learning and hypersensitivity to pain.	H2AZ2 H2AZ1	1.85e-05	2	150	2	32868857
Pubmed	Rab11b regulates the trafficking and recycling of the epithelial sodium channel (ENaC).	RAB11B RAB11A	1.85e-05	2	150	2	22129970
Pubmed	RAB11A and RAB11B control mitotic spindle function in intestinal epithelial progenitor cells.	RAB11B RAB11A	1.85e-05	2	150	2	37424454
Pubmed	The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken.	H2AZ2 H2AZ1	1.85e-05	2	150	2	16204459
Pubmed	Characterization of the histone H2A.Z-1 and H2A.Z-2 isoforms in vertebrates.	H2AZ2 H2AZ1	1.85e-05	2	150	2	20003410
Pubmed	Role of the histone variant H2A.Z.1 in memory, transcription, and alternative splicing is mediated by lysine modification.	H2AZ2 H2AZ1	1.85e-05	2	150	2	38366138
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	RAB11B ZNF142 LAMB2 JMJD1C GGCX ORC2 INTS5 NOP14 NKD2 INTS2 H2AZ1 AFDN SLC30A9 SNRNP200 HERPUD1 IGSF3 SYMPK	1.85e-05	1203	150	17	29180619
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	SPTBN2 OBSCN HUWE1 REV3L ZZZ3 DST SRGAP3 ALDH18A1 CHD6 SNRNP200 DOP1B SYMPK PIGM	1.98e-05	736	150	13	29676528
Pubmed	Afadin controls cell polarization and mitotic spindle orientation in developing cortical radial glia.	RAB11B RAB11A AFDN	2.18e-05	13	150	3	28482867
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	SPNS1 FNTB DTNB EPB41L5 LAMB2 MCM6 HUWE1 IPO4 PPP2CA SMC3 AFDN HOOK2 SNRNP200 SNTB2 KIF11	2.22e-05	974	150	15	28675297
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	DIDO1 XAB2 RTF1 RBM25 SNRNP200 SYMPK	2.24e-05	130	150	6	35545047
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	TRIO KALRN SPTBN2 DDN DBN1 PPP3CB SRGAP3 CDH10	3.21e-05	281	150	8	28706196
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TLK2 DIDO1 DBN1 HUWE1 ARHGAP35 INTS5 RBM25 NFRKB AFDN RIPOR1 SNAPC4 SNRNP200 SYMPK	3.33e-05	774	150	13	15302935
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	GTPBP4 H2AZ2 RAB11A DIDO1 MCM6 HUWE1 ARHGAP35 XAB2 RTF1 PPP2CA CCDC124 SMC3 ANP32A ALDH18A1 TFB2M HDAC10 SNRNP200 KIF11	4.14e-05	1415	150	18	28515276
Pubmed	An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.	H2AZ2 HEYL NOTCH3	4.23e-05	16	150	3	17273555
Pubmed	A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitis.	KIF21B MST1R INAVA	4.23e-05	16	150	3	25082827
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	GTPBP4 TRIO RAB11A MCM6 DBN1 HUWE1 IPO4 TESK1 PPP2CA RBM25 SMC3 ANP32A H2AZ1 ALDH18A1 AFDN CHST2 SNRNP200 KIF11	4.53e-05	1425	150	18	30948266
Pubmed	USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.	GTPBP4 SPTBN2 XAB2 NOP14 ALDH18A1	4.57e-05	90	150	5	35654790
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	GTPBP4 H2AZ2 ATAD5 DIDO1 JMJD1C XAB2 HMG20B ORC2 INTS5 RBM25 ZZZ3 DST INTS2 NFRKB CHD6 SNRNP200 SYMPK	4.62e-05	1294	150	17	30804502
Pubmed	Defining the membrane proteome of NK cells.	GTPBP4 DOCK8 HUWE1 IPO4 XAB2 ORC2 INTS5 SYNE3 NOP14 INTS2 PRF1 IGHMBP2 FUT7 HERPUD1 KIF11 PCNT	4.79e-05	1168	150	16	19946888
Pubmed	Hedgehog regulation of epithelial cell state and morphogenesis in the larynx.	RAB11B RAB11A SHH	5.12e-05	17	150	3	36398878
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	TRIO KALRN RAB11A DST SMC3 SRGAP3	5.18e-05	151	150	6	17043677
Pubmed	Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.	TLK2 SYMPK	5.53e-05	3	150	2	28535374
Pubmed	Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action.	TRIO KALRN	5.53e-05	3	150	2	31801062
Pubmed	Altered skeletal muscle phenotypes in calcineurin Aalpha and Abeta gene-targeted mice.	PPP2CB PPP3CB	5.53e-05	3	150	2	12773574
Pubmed	Golgi-resident TRIO regulates membrane trafficking during neurite outgrowth.	H2AZ2 TRIO	5.53e-05	3	150	2	31152060
Pubmed	Molecular cloning of a full-length cDNA encoding the catalytic subunit of human calmodulin-dependent protein phosphatase (calcineurin A alpha).	PPP2CA PPP3CB	5.53e-05	3	150	2	8392375
Pubmed	Transcriptional regulation mediated by H2A.Z via ANP32e-dependent inhibition of protein phosphatase 2A.	PPP2CA H2AZ1	5.53e-05	3	150	2	29524612
Pubmed	Drebrin preserves endothelial integrity by stabilizing nectin at adherens junctions.	DBN1 AFDN	5.53e-05	3	150	2	23750010
Pubmed	Tyrosine phosphorylation of protein phosphatase 2A in response to growth stimulation and v-src transformation of fibroblasts.	PPP2CA PPP2CB	5.53e-05	3	150	2	7510677
Pubmed	Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival.	H2AZ2 H2AZ1	5.53e-05	3	150	2	34525369
Pubmed	Mechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I2(PP2A)/SET.	PPP2CA ANP32A	5.53e-05	3	150	2	21806989
Pubmed	Chromatin remodeler Znhit1 preserves hematopoietic stem cell quiescence by determining the accessibility of distal enhancers.	H2AZ2 H2AZ1	5.53e-05	3	150	2	32694618
Pubmed	Rab11-mediated post-Golgi transport of the sialyltransferase ST3GAL4 suggests a new mechanism for regulating glycosylation.	RAB11B RAB11A	5.53e-05	3	150	2	33524390
Pubmed	Distinct functions of Trio GEF domains in axon outgrowth of cerebellar granule neurons.	H2AZ2 TRIO	5.53e-05	3	150	2	30850274
Pubmed	Notch3 regulates Mybl2 via HeyL to limit proliferation and tumor initiation in breast cancer.	HEYL NOTCH3	5.53e-05	3	150	2	36854682
Pubmed	Frequent amplifications and abundant expression of TRIO, NKD2, and IRX2 in soft tissue sarcomas.	TRIO NKD2	5.53e-05	3	150	2	16752383
Pubmed	Identification and characterization of the two isoforms of the vertebrate H2A.Z histone variant.	H2AZ2 H2AZ1	5.53e-05	3	150	2	20299344
Pubmed	PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity.	PRF1 PDCD1LG2	5.53e-05	3	150	2	28302645
Pubmed	The H2A.Z histone variant integrates Wnt signaling in intestinal epithelial homeostasis.	H2AZ2 H2AZ1	5.53e-05	3	150	2	31015444
Pubmed	The catalytic subunit of protein phosphatase 2A is carboxyl-methylated in vivo.	PPP2CA PPP2CB	5.53e-05	3	150	2	8206937
Pubmed	The P300/XBP1s/Herpud1 axis promotes macrophage M2 polarization and the development of choroidal neovascularization.	XBP1 HERPUD1	5.53e-05	3	150	2	34057287
Pubmed	The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking.	RAB11B RAB11A	5.53e-05	3	150	2	21291502
Pubmed	Spatiotemporal transcriptome atlas reveals the regional specification of the developing human brain.	H2AZ2 H2AZ1	5.53e-05	3	150	2	38091994
Pubmed	Interactions of myosin vb with rab11 family members and cargoes traversing the plasma membrane recycling system.	RAB11B RAB11A	5.53e-05	3	150	2	16473633
Pubmed	The transcription factor XBP1s restores hippocampal synaptic plasticity and memory by control of the Kalirin-7 pathway in Alzheimer model.	KALRN XBP1	5.53e-05	3	150	2	27646263
Pubmed	Recycling Endosomes in Mature Epithelia Restrain Tumorigenic Signaling.	RAB11B RAB11A	5.53e-05	3	150	2	31239271
Pubmed	Nef-induced alteration of the early/recycling endosomal compartment correlates with enhancement of HIV-1 infectivity.	RAB11B RAB11A	5.53e-05	3	150	2	15569681
Pubmed	Mutation of Tyr307 and Leu309 in the protein phosphatase 2A catalytic subunit favors association with the alpha 4 subunit which promotes dephosphorylation of elongation factor-2.	PPP2CA PPP2CB	5.53e-05	3	150	2	10441131
Pubmed	Protein phosphatase 2A dephosphorylates CaBP4 and regulates CaBP4 function.	PPP2CA PPP2CB	5.53e-05	3	150	2	23341017
Pubmed	Localization of the genes encoding the catalytic subunits of protein phosphatase 2A to human chromosome bands 5q23-->q31 and 8p12-->p11.2, respectively.	PPP2CA PPP2CB	5.53e-05	3	150	2	8383590
Pubmed	Overlapping binding sites in protein phosphatase 2A for association with regulatory A and alpha-4 (mTap42) subunits.	PPP2CA PPP2CB	5.53e-05	3	150	2	15252037
Pubmed	Recycling and Endosomal Sorting of Protease-activated Receptor-1 Is Distinctly Regulated by Rab11A and Rab11B Proteins.	RAB11B RAB11A	5.53e-05	3	150	2	26635365
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	KALRN OBSCN PPP2CA PPP2CB SMC3 ZER1 AFDN SNRNP200	5.59e-05	304	150	8	32235678
Interaction	TOP3B interactions	SETD1A MAN2A2 SPG7 TRIO KALRN FNTB SPEG SPTBN2 OBSCN LAMB2 UBL4A HUWE1 REV3L ARHGAP35 IPO4 TESK1 MST1R PPP2CB HEYL INTS5 LLGL2 SYNE3 DST NAPRT RALGPS1 ZER1 RIPOR1 SNAPC4 IGSF3 PCNT SYMPK	1.04e-07	1470	150	31	int:TOP3B
Interaction	RAC1 interactions	RAB11B RAP1GDS1 H2AZ2 TRIO KALRN DOCK8 SPTBN2 RAB11A EPB41L5 PARD6G BRINP1 HUWE1 ARHGAP35 IPO4 ARHGAP22 PPP2CA TAOK3 LLGL2 DST ARHGAP31 SRGAP3 SNTB2 IGSF3	3.87e-06	1063	150	23	int:RAC1
Cytoband	Ensembl 112 genes in cytogenetic band chr9q34	ASB6 SURF2 C9orf50 ZER1 SARDH SNAPC4 FUT7	1.04e-04	325	150	7	chr9q34
GeneFamily	Protein phosphatase catalytic subunits\|EF-hand domain containing	PPP2CA PPP2CB PPP3CB	4.65e-05	13	101	3	693
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP35 ARHGAP22 ARHGAP31 SRGAP3	1.73e-04	50	101	4	721
Coexpression	GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG2_AND_FOXP3_TRASDUCED_UP	IPO4 FAN1 CD163L1 DCHS1 CHD6 IGSF21 CDH10 NOTCH3	1.86e-06	144	150	8	M9003
Coexpression	KAUFFMANN_DNA_REPLICATION_GENES	MCM6 REV3L TERT ORC2 PPP2CA PPP2CB SMC3 IGHMBP2	2.06e-06	146	150	8	M9372
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-Treg\|Int-URO / Disease, condition lineage and cell class	SCG5 PARD6G RILPL1 CCDC167 ADAM12 SRGAP3 FUT7 DMTN	4.06e-07	200	150	8	47f265336bc3b8052c0cac730ac9afd41cd8fc43
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	SCG5 ASB6 ARHGAP31 DCHS1 CHST2 FUT7 PDCD1LG2	1.43e-06	164	150	7	d2218d50e0e2d19f919dcb460b3840687c082810
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SETD1A MYO9A DBN1 KMO SRGAP3 HDAC10 FUT7	2.20e-06	175	150	7	bb058e714d21a0ec8532eaf3c7dd2faf78016bc0
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIO PARD6G ARHGAP35 INTS5 ALDH18A1 INAVA IGSF3	2.75e-06	181	150	7	4e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIO PARD6G ARHGAP35 INTS5 ALDH18A1 INAVA IGSF3	2.75e-06	181	150	7	ad30c01290fb98adbd0caed301a584761212c977
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIO PARD6G ARHGAP35 INTS5 ALDH18A1 INAVA IGSF3	2.75e-06	181	150	7	3a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPB41L5 DDN PARD6G FRMD1 ITIH5 DST RIPOR1	3.18e-06	185	150	7	b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPB41L5 DDN PARD6G FRMD1 ITIH5 RIPOR1 CDH10	3.54e-06	188	150	7	9db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPB41L5 DDN PARD6G FRMD1 ITIH5 RIPOR1 CDH10	3.54e-06	188	150	7	047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCell	cellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KIF21B KALRN BTN2A2 ARHGAP31 DCHS1 RIPOR1 SNAPC4	3.66e-06	189	150	7	bccb3481ffed597c845fe860da658505316105b5
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T\|bone_marrow / Manually curated celltypes from each tissue	H2AZ2 ATAD5 MCM6 CCDC167 SMC3 H2AZ1 KIF11	3.92e-06	191	150	7	210a0f1a71df2508cbfc73d6868a2122338b9a1c
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRIB2 H2AZ2 MCM6 CCDC167 SMC3 SURF2 ANP32A	4.06e-06	192	150	7	694626965faee8b7c4e5bb78d554f62ba8dbc423
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPB41L5 DDN PARD6G FRMD1 ITIH5 DST RIPOR1	4.06e-06	192	150	7	ef0aba777072429a6ab7dcfcc305673975946580
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPB41L5 DDN PARD6G FRMD1 ITIH5 DST RIPOR1	4.20e-06	193	150	7	3eaa0461618582a1754400624350d269d24e750a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A EPB41L5 LLGL2 SRGAP3 RALGPS1 KCNIP4 AFDN	4.50e-06	195	150	7	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	H2AZ2 ATAD5 MCM6 CCDC167 SMC3 H2AZ1 KIF11	5.14e-06	199	150	7	4394dcd1809f49e9bada8f5e115d5123356eae3e
ToppCell	remission-T/NK_proliferative\|remission / disease stage, cell group and cell class	H2AZ2 ATAD5 MCM6 CCDC167 SMC3 H2AZ1 KIF11	5.14e-06	199	150	7	303a5fc43a48b05b6f2060d99eef4adc36f8d4e3
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	H2AZ2 ATAD5 MCM6 CCDC167 SMC3 H2AZ1 KIF11	5.14e-06	199	150	7	c0ea391bb347b99b94b5d7f02612ede938986745
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	H2AZ2 ATAD5 MCM6 CCDC167 SMC3 H2AZ1 KIF11	5.14e-06	199	150	7	96af1f289552f38f2dfa181192eb3276f4c7d70b
ToppCell	remission-T/NK_proliferative\|World / disease stage, cell group and cell class	H2AZ2 ATAD5 MCM6 CCDC167 SMC3 H2AZ1 KIF11	5.14e-06	199	150	7	f305f3a454b7d2170429bad087480ccccca19acd
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pre_pro_B_progenitor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	H2AZ2 ATAD5 CCDC167 SMC3 CLEC14A H2AZ1 KIF11	5.14e-06	199	150	7	99778178e3ec121802db938db8c5475d19b43fec
ToppCell	COVID-19_Convalescent-Lymphoid_T/NK-T/NK_proliferative\|COVID-19_Convalescent / Disease group, lineage and cell class	H2AZ2 ATAD5 MCM6 CCDC167 SMC3 H2AZ1 KIF11	5.14e-06	199	150	7	893b78c661c529db07a5fcc3124d9b3d0f270fa5
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	H2AZ2 ATAD5 MCM6 CCDC167 SMC3 H2AZ1 KIF11	5.14e-06	199	150	7	5b18e18ddbf4bd53aa0d574d23092cb96da7f400
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-Other_T\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	H2AZ2 ATAD5 MCM6 CCDC167 SMC3 H2AZ1 KIF11	5.14e-06	199	150	7	6df65f4c2f9a125e0c7c4f597fefc05a97fc8831
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-Other_T\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	H2AZ2 ATAD5 MCM6 CCDC167 SMC3 H2AZ1 KIF11	5.14e-06	199	150	7	cb229aa3eb7b1cc47e76711b8fc18fce88a5cf08
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DTNB XBP1 LLGL2 SRGAP3 ALDH18A1 HOOK2 DOP1B	5.31e-06	200	150	7	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	COVID-19-COVID-19_Convalescent-Lymphocyte-T/NK-T/NK_proliferative\|COVID-19_Convalescent / Disease, condition lineage and cell class	H2AZ2 ATAD5 MCM6 CCDC167 SMC3 H2AZ1 KIF11	5.31e-06	200	150	7	00538c4cbab5da00b3a366717d38a3ba5cfe3f65
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte-\|COVID_vent / Disease condition, Lineage, Cell class and subclass	H2AZ2 ATAD5 MCM6 SMC3 PRF1 H2AZ1 KIF11	5.31e-06	200	150	7	7e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte\|COVID_vent / Disease condition, Lineage, Cell class and subclass	H2AZ2 ATAD5 MCM6 SMC3 PRF1 H2AZ1 KIF11	5.31e-06	200	150	7	9775ca7dedb76fcbb74f80f86b33c94e394c320a
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|367C / Donor, Lineage, Cell class and subclass (all cells)	RNPC3 SMC3 SRGAP3 IGHMBP2 ZER1 DOP1B	1.15e-05	149	150	6	41f28138bde45d0b814e116837e5a32b5e80d54a
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SCG5 NKD2 ASB6 PRF1 CHST2 PDCD1LG2	1.73e-05	160	150	6	955acb023ce4ccfac5073c9d693db87db3856187
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DDN PARD6G FRMD1 DST RIPOR1 CDH10	2.27e-05	168	150	6	315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DDN PARD6G FRMD1 DST RIPOR1 CDH10	2.27e-05	168	150	6	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PARD6G ADAM12 HEYL NKD2 CHST2 NOTCH3	2.43e-05	170	150	6	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DDN PARD6G FRMD1 DIO3 RIPOR1 CDH10	2.59e-05	172	150	6	381ae1c3c07d0a424f43455ec571653b192a946a
ToppCell	droplet-Lung-nan-21m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KMO ARHGAP22 MTRF1 SRGAP3 FUT7 KIF11	2.68e-05	173	150	6	2eb6e9fc3a3654f6f86fbd112e80a18814afd103
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATAD5 DBN1 TERT ALDH18A1 KIF11 IGSF3	2.68e-05	173	150	6	f38bf7584e08d15a6e2c116b7c3551ba475a5e14
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DDN PARD6G FRMD1 DIO3 RIPOR1 CDH10	2.77e-05	174	150	6	dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCell	COVID-19-kidney-Podocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EPB41L5 DDN PARD6G FRMD1 ITIH5 RIPOR1	2.86e-05	175	150	6	a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCell	ILEUM-non-inflamed-(5)_Plasmablasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PRELID1 XBP1 CCDC167 TERT CHST2 HERPUD1	3.25e-05	179	150	6	58c8996120637315dcbd1991a71516c09173051e
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac\|lymph-node_spleen / Manually curated celltypes from each tissue	HK3 SCG5 CD163L1 IGSF21 NOTCH3 KIF11	3.35e-05	180	150	6	4eea8366cdb82c356325ce88f09ad8b302c17a07
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPB41L5 DDN PARD6G FRMD1 ITIH5 RIPOR1	3.67e-05	183	150	6	612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPB41L5 DDN PARD6G FRMD1 ITIH5 RIPOR1	3.67e-05	183	150	6	848fc6dd129150897ee339343e83c645b6e779eb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPB41L5 DDN PARD6G FRMD1 ITIH5 RIPOR1	3.67e-05	183	150	6	eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRIB2 DDN PARD6G FRMD1 DST RIPOR1	3.90e-05	185	150	6	9197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRIB2 DDN PARD6G FRMD1 DST RIPOR1	3.90e-05	185	150	6	ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RNPC3 SMC3 SRGAP3 IGHMBP2 ZER1 DOP1B	4.02e-05	186	150	6	74c238759c5d3fd39127ec0060d0c2cb16b326d4
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi\|lung / Disease (COVID-19 only), tissue and cell type	SCG5 XBP1 TERT SYNE3 HERPUD1 KIF11	4.02e-05	186	150	6	66676d9395172de5707e204826a1c9f73b448cca
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	REV3L JMJD1C DST SRGAP3 CD163L1 HERPUD1	4.14e-05	187	150	6	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPB41L5 DDN PARD6G FRMD1 DST RIPOR1	4.14e-05	187	150	6	24c2a3962da364e46e98abeab5f8234376fa26bb
ToppCell	Fibroblast-E_(Early_Fibroblastic_progenitor)\|World / shred on cell class and cell subclass (v4)	H2AZ2 ATAD5 HEYL H2AZ1 NOTCH3 KIF11	4.27e-05	188	150	6	be3db9768364568f44e32ae6b3bf99e49b0978bb
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SCG5 XBP1 TERT SYNE3 HERPUD1 KIF11	4.27e-05	188	150	6	567b08514d9d84cbb40f9b7a679eec304f023428
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SHH LLGL2 TMEM132D RALGPS1 KCNIP4 CDH10	4.40e-05	189	150	6	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TRIB2 ITIH5 HEYL NKD2 CHST2 NOTCH3	4.53e-05	190	150	6	84fbd5664ec886120963d4f50dfa1fd1851d36c1
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	H2AZ2 ATAD5 CCDC167 H2AZ1 FUT7 KIF11	4.94e-05	193	150	6	b835d28de9daeec5213172c96f62b332cda53bb5
ToppCell	normal_Pleural_Fluid-Myeloid_cells-Activated_DCs\|Myeloid_cells / Location, Cell class and cell subclass	ADAM12 BTN2A2 H2AZ1 AFDN CHST2 PDCD1LG2	5.08e-05	194	150	6	30f683725cb13ae32ef6846618801ec78e12397d
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	H2AZ2 ATAD5 CCDC167 H2AZ1 FUT7 KIF11	5.23e-05	195	150	6	67670d16ddd5d5ab7bc2254df329f5a7b2581556
ToppCell	IPF-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	KALRN DOCK8 PARD6G SRGAP3 DMTN IGSF3	5.23e-05	195	150	6	de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	H2AZ2 ATAD5 CCDC167 H2AZ1 FUT7 KIF11	5.23e-05	195	150	6	23dc2f8a3a038195a31feee7e3a51094a7a7c23e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A EPB41L5 LLGL2 SRGAP3 RALGPS1 KCNIP4	5.38e-05	196	150	6	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NBEAL1 LAMB2 ITIH5 BMP1 HEYL NOTCH3	5.53e-05	197	150	6	2872a78b1be61aa1d50bc9a49294a21e922dc033
ToppCell	10x5'-GI_large-bowel-Lymphocytic_B-GC_B_(I)\|GI_large-bowel / Manually curated celltypes from each tissue	H2AZ2 MCM6 CCDC167 TERT H2AZ1 KIF11	5.53e-05	197	150	6	80a0cfbd454409594effead7082586b06c2f411a
ToppCell	normal_Lung-T/NK_cells-Undetermined\|normal_Lung / Location, Cell class and cell subclass	H2AZ2 ATAD5 CCDC167 SMC3 H2AZ1 KIF11	5.69e-05	198	150	6	c65cdb54409087014125a76627e5efb5fe8dabc9
ToppCell	tumor_Lung-T/NK_cells-Undetermined\|tumor_Lung / Location, Cell class and cell subclass	H2AZ2 ATAD5 MCM6 SMC3 H2AZ1 KIF11	5.85e-05	199	150	6	2e222e2e080bc2be63d0fdf285e1790676b911ef
ToppCell	COVID-19_Convalescent-T/NK_proliferative\|COVID-19_Convalescent / Disease condition and Cell class	H2AZ2 ATAD5 MCM6 CCDC167 H2AZ1 KIF11	5.85e-05	199	150	6	c608d953b852b67a4e36bd63d45f0deec3eefbd9
ToppCell	Bronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	OBSCN PARD6G HEYL DST DIO3 NOTCH3	5.85e-05	199	150	6	929f809579368201331d9099d8904b6e3c41797b
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ATAD5 CCDC167 SMC3 C6orf15 H2AZ1 KIF11	5.85e-05	199	150	6	c7c501ad144ac5488d0b0496554d46616f2e01a6
ToppCell	Bronchial-NucSeq-Stromal-Pericyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	OBSCN PARD6G HEYL DST DIO3 NOTCH3	5.85e-05	199	150	6	854628ce91068093c14bd4d45ba38c41469f3549
ToppCell	MS-IIF-Lymphocyte-T/NK-MAIT\|IIF / Disease, condition lineage and cell class	DDN XBP1 DBN1 ADAM12 PRF1 HERPUD1	6.02e-05	200	150	6	7518bbf1c713b74f89be25ee700c6b0edc16ee8a
ToppCell	COVID_non-vent-Lymphocytic-Proliferative_Lymphocyte-\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	H2AZ2 ATAD5 MCM6 SMC3 H2AZ1 KIF11	6.02e-05	200	150	6	04bf9e6a0fbd792b49eed63dabba5d6fafed8c07
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	H2AZ2 ATAD5 MCM6 PRF1 H2AZ1 KIF11	6.02e-05	200	150	6	e269a61858ac610e914b684d9a3c084e9600fb1c
ToppCell	COVID_non-vent-Lymphocytic-Proliferative_Lymphocyte\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	H2AZ2 ATAD5 MCM6 SMC3 H2AZ1 KIF11	6.02e-05	200	150	6	f6b5320cdfe640a71e6e2df26f30d42e64b1c921
ToppCell	ILEUM-non-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TUT4 JMJD1C RBM25 DST HERPUD1	9.43e-05	135	150	5	b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SPEG RAB11A EPB41L5 PARD6G ASB6	1.01e-04	137	150	5	0c82f815c014d01213d23b466043d6e57186dceb
ToppCell	E18.5-samps-Mesenchymal-Pericyte-pericyte_D\|E18.5-samps / Age Group, Lineage, Cell class and subclass	DBN1 ITIH5 HEYL ALDH18A1 NOTCH3	1.50e-04	149	150	5	dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCell	Int-URO-Lymphocyte-T_NK-CD8_Naive\|Int-URO / Disease, Lineage and Cell Type	TRIB2 OBSCN PARD6G MCM6 ALDH18A1	1.64e-04	152	150	5	52d6f9cf1f4637c922f582705d625b4cbe3dc0c2
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPEG HEYL DCHS1 CHST2 PIGM	1.75e-04	154	150	5	16fdafb5c64d2db321554f87129a962d113f1668
ToppCell	Int-URO-Lymphocyte-T_NK-Treg\|Int-URO / Disease, Lineage and Cell Type	SCG5 RILPL1 ADAM12 SRGAP3 DMTN	1.97e-04	158	150	5	457d64dceedb67bfff1303334cda1253a839b3d6
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF21B USP30 SHH MCM6 PRF1	2.09e-04	160	150	5	5cc1b75e3c20d83112b3aa2f3c749a6c73910a2d
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TERT PRF1 CD163L1 FUT7 KIF11	2.09e-04	160	150	5	94e4f5fc2156dd8163811c3b8b0781ea9b3f2e06
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TULP2 MTRF1 ARHGAP31 SNAPC4 DMTN	2.27e-04	163	150	5	0ab043b68e8739adcedda01165a3758cd0d22728
ToppCell	LV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	KALRN NBEAL1 DOCK8 ITIH5 NOTCH3	2.41e-04	165	150	5	f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	HK3 SCG5 ARHGAP22 CD163L1 PIGM	2.54e-04	167	150	5	a48349f189f6a8d563744b0a294c3974f3a18f50
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	SCG5 PPP3CB CD163L1 ZER1 PIGM	2.62e-04	168	150	5	8459d0a1bf6d4b5c83001097331f8b78fceb9305
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DDN PARD6G FRMD1 RIPOR1 CDH10	2.62e-04	168	150	5	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCG5 FAM135B TMEM132D RALGPS1 IGSF21	2.62e-04	168	150	5	0f736d58cb0ff042fa3ce58e36bde37b6976f8fc
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_C\|368C / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 SPEG SRGAP3 IGHMBP2 DMTN	2.62e-04	168	150	5	0372c06b70f0ba95bf8cd1363ca7c5f31207f094
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATAD5 MCM6 ITIH5 HEYL CDH10	2.69e-04	169	150	5	335619507857383c3b0b507cdf05d786ed59e585
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DDN PARD6G FRMD1 ITIH5 RIPOR1	2.76e-04	170	150	5	60bbd738c12e64e483485586c30057304884f5a6
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	KALRN DTNB KMO INAVA SARDH	2.76e-04	170	150	5	09bcbc7eb3b1d35cf03f01ce2f2fe37373382dd4
ToppCell	droplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN DDN KMO DST NOTCH3	2.84e-04	171	150	5	4e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATAD5 SPTBN2 ARHGAP35 MST1R DST	2.84e-04	171	150	5	ea60d9e9df28ab991fbdb596784b44f6a9fc5827
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	KALRN NBEAL1 DOCK8 ITIH5 NOTCH3	2.84e-04	171	150	5	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	E15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TRIB2 RAB11A DST ARHGAP31 CLEC14A	2.84e-04	171	150	5	3112d15f2a28cf4a71992db4971d960716dc1264
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATAD5 HEYL C6orf15 C9orf50 NOTCH3	2.91e-04	172	150	5	03a0aff6b7971093a4347b5ed12546d78374c56f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DDN PARD6G FRMD1 DST RIPOR1	2.91e-04	172	150	5	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDN RILPL1 ADAM12 KMO SRGAP3	2.91e-04	172	150	5	30916a902c151907745756d14327e24adc34afef
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN2A2 FNTB SRGAP3 ZER1 PDCD1LG2	2.99e-04	173	150	5	6e92983d9f8a2a37f23e60a0d5bb1738217897bc
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-Alox5+_Lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN2A2 FNTB SRGAP3 ZER1 PDCD1LG2	2.99e-04	173	150	5	4c788c1dad1da495b3b5c10f95e779848dfe85dc
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRIB2 C1orf167 CLEC14A FUT7 CDH10	3.07e-04	174	150	5	6b5ff1cc5fe6705f7ea70b5a892dfbf91e32288d
Computational	Neighborhood of NF2	SETD1A H2AZ2 FNTB MYO9A FAN1 INTS5 ASB6 RALGPS1 ZER1 AFDN RIPOR1 SNRNP200	2.48e-05	302	101	12	GCM_NF2
Disease	Intellectual Disability	TLK2 SETD1A RAB11B ZNF142 TRIO DOCK8 RAB11A PPP2CA SRGAP3 TFB2M	8.16e-05	447	146	10	C3714756
Disease	red blood cell density measurement	RAB11B TRIB2 H2AZ2 KALRN FNTB MYO9A RAB11A EPB41L5 XBP1 TERT JMJD1C DST AFDN KIF11	1.26e-04	880	146	14	EFO_0007978
Disease	Aplastic anemia	TERT PRF1	2.41e-04	5	146	2	cv:C0002874
Disease	Aplastic anemia, idiopathic	TERT PRF1	2.41e-04	5	146	2	C0348890
Disease	APLASTIC ANEMIA	TERT PRF1	2.41e-04	5	146	2	609135
Disease	inflammatory bowel disease (implicated_via_orthology)	RAB11B RAB11A XBP1	2.52e-04	25	146	3	DOID:0050589 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	HK3 KALRN OBSCN XBP1 DBN1 ADAM12 TERT TESK1 BMP1 HEYL LLGL2 SRGAP3 DIO3 CDH10 NOTCH3	2.95e-04	1074	146	15	C0006142
Disease	schizophrenia (implicated_via_orthology)	SETD1A MAN2A2 KMO SRGAP3	3.66e-04	68	146	4	DOID:5419 (implicated_via_orthology)
Disease	Aplastic Anemia	TERT PRF1	5.02e-04	7	146	2	C0002874
Disease	Hypoplastic anemia	TERT PRF1	5.02e-04	7	146	2	C0178416
Disease	intestinal cancer (implicated_via_orthology)	RAB11B RAB11A NOTCH3	5.30e-04	32	146	3	DOID:10155 (implicated_via_orthology)
Disease	focal segmental glomerulosclerosis (is_marker_for)	SHH PPP3CB	6.68e-04	8	146	2	DOID:1312 (is_marker_for)
Disease	Colorectal Carcinoma	HK3 KALRN SCG5 SPTBN2 OBSCN BRINP1 ZZZ3 ANP32A DCHS1 IGSF21 SNRNP200	7.69e-04	702	146	11	C0009402
Disease	cancer	SPG7 ATAD5 SCG5 TERT FAM83C GGCX RBM25 FIGLA	8.83e-04	400	146	8	MONDO_0004992
Disease	Neurodevelopmental Disorders	TRIO DOCK8 SMC3 SRGAP3	1.19e-03	93	146	4	C1535926
Disease	Neuroblastoma	DOCK8 TERT CHD6	1.64e-03	47	146	3	C0027819
Disease	response to cisplatin	DTNB ARHGAP35 C6orf15	2.08e-03	51	146	3	GO_0072718
Disease	platelet crit	USP30 TRIB2 SPATA6L H2AZ2 KALRN FNTB EPB41L5 TERT JMJD1C DCHS1 CHST2 NOTCH3	2.82e-03	952	146	12	EFO_0007985
Disease	MHPG measurement, 5-HIAA measurement	ADAM12 CLEC14A	3.15e-03	17	146	2	EFO_0005132, EFO_0005133
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	TLK2 TRIO	3.15e-03	17	146	2	DOID:0060307 (is_implicated_in)
Disease	neutrophil percentage of leukocytes	KALRN DOCK8 ATAD5 RAB11A MCM6 TERT JMJD1C RTF1 SNAPC4	3.44e-03	610	146	9	EFO_0007990
Disease	Uterine leiomyoma, estrogen-receptor positive breast cancer	ATAD5 TERT	3.53e-03	18	146	2	EFO_1000649, HP_0000131
Disease	Adenocarcinoma of lung (disorder)	ARHGAP35 IPO4 TAOK3 ANP32A ALDH18A1	3.68e-03	206	146	5	C0152013
Disease	non-lobar intracerebral hemorrhage	NBEAL1 XBP1 NLRP13	3.79e-03	63	146	3	EFO_0010178
Disease	free cholesterol to total lipids in medium LDL percentage	RAB11B JMJD1C HERPUD1	3.79e-03	63	146	3	EFO_0022283
Disease	white matter hyperintensity measurement	NBEAL1 ARHGAP35 TAOK3 AP5B1 CHD6 HOOK2	4.01e-03	302	146	6	EFO_0005665
Disease	selenium measurement, response to dietary selenium supplementation	TRIO GPR156	4.36e-03	20	146	2	EFO_0006331, EFO_0600021
Disease	Global developmental delay	ZNF142 SPTBN2 RAB11A PPP2CA	4.38e-03	133	146	4	C0557874
Disease	rheumatoid arthritis, ulcerative colitis	INAVA SNAPC4	4.80e-03	21	146	2	EFO_0000685, EFO_0000729

Protein segments in the cluster

Peptide	Gene	Start	Entry
RQHDEAARRLLEPEA	AFDN	1666	P55196
TEEIAIPLRRSSRHQ	ATAD5	721	Q96QE3
PHIDRLAREGVRLTQ	ARSF	56	P54793
EEEIAQRLLSHPRQR	C1orf167	596	Q5SNV9
RSSLRAFLDPHRNLE	C9orf50	381	Q5SZB4
RNTAIERRDLVRHPV	BRINP1	81	O60477
TTHPLRELEELLRAQ	BTBD16	116	Q32M84
VLNRLHLAIPTRRDD	GTPBP4	356	Q9BZE4
RITPRHLQLAIRGDE	H2AZ2	81	Q71UI9
DPLARTTRLTHALAR	ADAM12	861	O43184
TPDRVSEADIQRLLH	SCG5	31	P05408
RIHLELRNRTPSDVK	ANP32A	6	P39687
RRDRIHESSPLDLAS	ASB6	131	Q9NWX5
AIRVSREPHFTERTL	CD163L1	736	Q9NR16
LREAVSRIRRHTAPD	DDN	611	O94850
TRPDRDRHVSIVREN	BMP1	226	P13497
RDHLTARPSDLELVA	NWD1	91	Q149M9
LLRLLRVDESESVHP	NBEAL1	531	Q6ZS30
SDLRHLRAVPTDEAR	RAB11A	126	P62491
SDLRHLRAVPTDEAR	RAB11B	126	Q15907
EPESTLRALRLLHDL	RBM25	136	P49756
TSPHRERATLLEEQL	PDCD1LG2	66	Q9BQ51
ARHLLDDSVLESRSP	RALGPS1	366	Q5JS13
SPNQRHRDLELSGDR	HERPUD1	16	Q15011
LSVVRPLDREQRAEH	DCHS1	1601	Q96JQ0
DLPTRHKIRELTSSR	MCM6	116	Q14566
SDAVLQRLPEEARHR	LLGL2	171	Q6P1M3
NKAREHSLLRSDRPA	NFRKB	561	Q6P4R8
DALFTILHDLRPQDR	ITIH5	316	Q86UX2
IPQHRSLEDRVSAAR	DIO3	216	P55073
RTPLERDDLHESVFR	DST	1091	Q03001
PELHSLRTQLRERDV	HOOK2	626	Q96ED9
STLVRTEPREHLLDQ	KIF11	936	P52732
SEHLRVPRVSLERDD	DOP1B	601	Q9Y3R5
VIRAVSHRDSRNPDL	JMJD1C	41	Q15652
LHVLLDSQDPRREAL	PRF1	346	P14222
LDLFDSTRDPDTRHR	KIF21B	156	O75037
RELQTRRSHLPLAQR	FUT7	96	Q11130
LTLEFEHSDSPRRLR	INTS2	126	Q9H0H0
EHSDSPRRLRLVLSE	INTS2	131	Q9H0H0
VRHRPEALELLEAQS	KCNIP4	66	Q6PIL6
PARSNHDRIRQEDLR	KALRN	61	O60229
ANREITDHLDRLPRD	NOTCH3	1996	Q9UM47
TDHLDRLPRDVAQER	NOTCH3	2001	Q9UM47
RADPVRIRLLSHLNS	HEYL	141	Q9NQ87
RLHTLGDNLLDPRRE	LAMB2	251	P55268
ERSLTAREHSPEEAR	AP5B1	251	Q2VPB7
AREHSPEEARELRAA	AP5B1	256	Q2VPB7
SSPVLHRLRLREDEN	DBN1	141	Q16643
SPSIDTLDHIRALDR	PPP2CB	171	P62714
TLDHIRALDRLQEVP	PPP2CB	176	P62714
SPSIDTLDHIRALDR	PPP2CA	171	P67775
TLDHIRALDRLQEVP	PPP2CA	176	P67775
RLRAPTSTEANHIRL	NOP14	671	P78316
RLLEETLAPFRLNHD	HK3	481	P52790
DEPKLNTSRLHRVLR	HUWE1	3196	Q7Z6Z7
EEPRVADRRLSAHVR	NKD2	206	Q969F2
LQEKSLEHLRLPDRS	PCNT	2501	O95613
LEHLRLPDRSSLLSE	PCNT	2506	O95613
LHSRELSPEARRSLE	CCDC167	36	Q9P0B6
QRLLSSLRADPRHSL	PARD6G	346	Q9BYG4
HRDLLRTPLFDQIID	ALDH18A1	621	P54886
RERDILAALSHPLVT	OBSCN	6511	Q5VST9
ASLLHQDSESRRLPR	C6orf15	166	Q6UXA7
LHSRELRTPRNALAA	GALR2	131	O43603
SEHRDVLVLLPSREQ	FRMD1	51	Q8N878
ERLREAQRAATHIPA	EPB41L5	21	Q9HCM4
RPHESLAREEALTAL	HDAC10	446	Q969S8
LQDSRPFRSLLHRDL	IGSF21	206	Q96ID5
HPERETVARLSRDAT	IGSF3	861	O75054
SRLRIPDDHAISDLS	KMO	346	O15229
RAPDFNEEHLRRSLR	DOCK8	1561	Q8NF50
SPIRFSLDRHTDLDR	CDH10	416	Q9Y6N8
SPLEQLRHLAEELRL	CCNDBP1	16	O95273
NLVRVESRDDHLSLP	CHD6	1661	Q8TD26
PLVLRHSEAARLAAD	FAM83C	36	Q9BQN1
QILHRLLADERSAPE	RAP1GDS1	536	P52306
NHRDPRQARRLATET	DIDO1	1556	Q9BTC0
VLDSPSRLDEEHRLI	DTNB	391	O60941
RQLSVSRHEAFPLRV	MAN2A2	741	P49641
LRPEHARERLQDDSV	FNTB	26	P49356
RHLENSEEPPERRSR	GPR156	526	Q8NFN8
RITPRHLQLAIRGDE	H2AZ1	81	P0C0S5
RSLDRFPEVELLSHR	FIGLA	201	Q6QHK4
RSRALELPSDREVLH	FAM135B	701	Q49AJ0
IALENPRTRSLHRAL	FAM135B	886	Q49AJ0
AHPELFLSEDRRSVR	BTN2A2	336	Q8WVV5
SLLEHVELPRSRERS	DMTN	71	Q08495
LSPEIHTLDDIRRLD	PPP3CB	211	P16298
LHREDPLSSLERQLA	INAVA	181	Q3KP66
FPLLARERHDRVRDN	IPO4	946	Q8TEX9
EDTLRRDHQLREAPD	CCDC124	101	Q96CT7
LNERREQIRTRHPDL	HMG20B	81	Q9P0W2
LRKRLIVPRSHSDSE	ORC2	166	Q13416
RLQLIHDAPEESLRA	FAN1	886	Q9Y2M0
PEELNRVRLSRHKLE	RTF1	356	Q92541
RTFDRALRALPITQH	XAB2	131	Q9HCS7
RFLEERHESRRPLST	SPATA6L	141	Q8N4H0
DEFSHLRPEQRLALL	SMC3	51	Q9UQE7
ETREPRERLLLTAAH	SHH	256	Q15465
HRKPSLRELRLDNSV	TMEM132D	276	Q14C87
IPRHRRRANLLQEEE	SYNE3	786	Q6ZMZ3
NSIRTLDRDLLRHSP	LRTM2	126	Q8N967
HREVTPDQKLLSRRL	PRELID1	41	Q9Y255
RLETRTHRPNVELCR	TEKT1	316	Q969V4
PTSAELLRHDFVRRD	TAOK3	266	Q9H2K8
IDHLRSLTPLDARDI	TFB2M	336	Q9H5Q4
RQRLTHLSPEEKALR	XBP1	61	P17861
FLREHPSLRLQTDAR	SURF2	11	Q15527
HLLSRARSPEELSLA	INTS5	521	Q6P9B9
LDRHVFIDLPTLQER	SPG7	471	Q9UQ90
EHLISSRFIRPSDRN	ARHGAP35	571	Q9NRY4
ENRRSLNRRHAELAP	MTRF1	101	O75570
RGVERTIRNLPLDHA	SETD1A	1201	O15047
LRPSDVEVELLAHTR	SARDH	116	Q9UL12
DSPTREHARRSEALQ	ARHGAP22	586	Q7Z5H3
HSLDPRRQELLEARF	TLK2	6	Q86UE8
ESLQVVRSRDPRAHR	CHST2	351	Q9Y4C5
LERRRSHCTLENEPL	CLEC14A	96	Q86T13
LSRDLSEPTERRHQS	C10orf90	461	Q96M02
RIDASQLPHRVLETR	SMIM2	6	Q9BVW6
DPRSTRLTRIHLRED	ZER1	76	Q7Z7L7
PDREHLTRNTARIRQ	TULP2	371	O00295
LQEIERRRNTPFHER	GGCX	666	P38435
DRTLLVRHLPAELTA	RNPC3	26	Q96LT9
SVELHARTRRDLEPD	REV3L	2301	O60673
IRSHRPTLDALREQA	SPTBN2	796	O15020
RLEVRAHPESRSLAV	SPEG	956	Q15772
NLLRHEDRPQRRSSV	SRGAP3	201	O43295
RPRFTLQELRDVLHE	RILPL1	291	Q5EBL4
DQPDLRTLHLERLQR	IGHMBP2	826	P38935
REPSERLTSQEILDH	TRIB2	291	Q92519
VEISRRLRHSNPRAD	SPNS1	341	Q9H2V7
LAQLSLSRLSPEHRR	NAPRT	496	Q6XQN6
RAQHSLPRAAALERT	TESK1	536	Q15569
RSLATNHPARKERRE	ARHGAP31	256	Q2M1Z3
SEIPRRQEHDISLDR	SYMPK	201	Q92797
RQEHDISLDRIPRDH	SYMPK	206	Q92797
IERPNLHDKSSRLVR	ZNF862	491	O60290
DPLLDQRRLDLVHTA	SNRNP200	946	O75643
TLDDIERLASRFLHP	UBL4A	131	P11441
SSLEDERDRQPRVTH	USP30	171	Q70CQ3
DLEQLRKIRRRSPHE	SLC30A9	146	Q6PML9
NDPDDLDVLRTRHAR	SNAPC4	1446	Q5SXM2
EAFPSRLALDEHRRQ	ZNF142	1361	P52746
DQLLIVRPVRSDHAR	VSIG10L	361	Q86VR7
DLENRLIELHSPDSR	SNTB2	261	Q13425
SRDVLDPRDLHDTRD	TUT4	1336	Q5TAX3
QSAHRRLEESLDALP	RIPOR1	1196	Q6ZS17
TLHLLPDRDNDKSLR	PIGM	191	Q9H3S5
HRTLTIELRRPENEF	TMLHE	356	Q9NVH6
RTLRNRSIAHPEEIS	ZZZ3	26	Q8IYH5
LHTRLARLSATEPEL	MST1R	276	Q04912
EDTDPRRLVQLLRQH	TERT	441	O14746
LSEAEVRQHREARPA	TERT	601	O14746
VRQHREARPALLTSR	TERT	606	O14746
PARSNHDRIRQEDLR	TRIO	91	O75962
PRSTDLILRHLTVAD	VN1R2	121	Q8NFZ6
EHEELQRLLDPNRTR	NLRP13	211	Q86W25
LVRERPRSLEDLHQK	MYO9A	1251	B2RTY4