Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LRP1B LRP1 LRP2	9.37e-05	16	113	3	GO:0005041
GeneOntologyMolecularFunction	apolipoprotein receptor activity	ABCA7 LRP1	9.49e-05	3	113	2	GO:0030226
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	LRP1B LRP1 LRP2	2.18e-04	21	113	3	GO:0030228
GeneOntologyMolecularFunction	activin receptor activity, type I	ACVR1C TGFBR1	3.14e-04	5	113	2	GO:0016361
GeneOntologyMolecularFunction	phosphatidylinositol binding	ARHGAP32 FRMPD4 INPPL1 NUMA1 SNX16 SNX30 SNX7 PLEKHA5	4.37e-04	316	113	8	GO:0035091
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	RERG DNAH3 MYO18A AGAP11 FANCM ABCA7 EEF2 MDN1 MTIF2 DDX23 KIF13A MOV10 AGAP2	4.41e-04	775	113	13	GO:0017111
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNAH3 MYH10 MYH11 MYO18A KIF13A	5.59e-04	118	113	5	GO:0003774
GeneOntologyMolecularFunction	pyrophosphatase activity	RERG DNAH3 MYO18A AGAP11 FANCM ABCA7 EEF2 MDN1 MTIF2 DDX23 KIF13A MOV10 AGAP2	9.22e-04	839	113	13	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	RERG DNAH3 MYO18A AGAP11 FANCM ABCA7 EEF2 MDN1 MTIF2 DDX23 KIF13A MOV10 AGAP2	9.32e-04	840	113	13	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	RERG DNAH3 MYO18A AGAP11 FANCM ABCA7 EEF2 MDN1 MTIF2 DDX23 KIF13A MOV10 AGAP2	9.32e-04	840	113	13	GO:0016818
GeneOntologyMolecularFunction	phospholipid binding	ARHGAP32 FRMPD4 INPPL1 NUMA1 AGAP11 SNX16 SNX30 MYOF SNX7 PLEKHA5	1.11e-03	548	113	10	GO:0005543
GeneOntologyMolecularFunction	activin receptor activity	ACVR1C TGFBR1	1.11e-03	9	113	2	GO:0017002
GeneOntologyMolecularFunction	cargo receptor activity	LRP1B ABCA7 LRP1 LRP2	1.38e-03	85	113	4	GO:0038024
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	PDGFRB RET ACVR1C TGFBR1	1.38e-03	85	113	4	GO:0019199
GeneOntologyMolecularFunction	lipoprotein particle receptor binding	HSPG2 LRP1 LRP2	1.39e-03	39	113	3	GO:0070325
GeneOntologyBiologicalProcess	positive regulation of cellular component organization	ARHGAP32 FRMPD4 PDGFRB HYAL1 SRC NUMA1 MYO18A CKAP5 PIWIL2 RET ABCA7 TGFBR1 SNX30 SETDB1 SNX7 ANAPC2 LRP1 LRP2 PRKCA TNKS2 ADGRL2	9.56e-06	1366	110	21	GO:0051130
GeneOntologyCellularComponent	myosin filament	MYH10 MYH11 MYO18A MYOM2	8.74e-06	25	111	4	GO:0032982
GeneOntologyCellularComponent	dendrite	ARHGAP32 MYH10 FRMPD4 SRC NUMA1 CKAP5 BRINP1 RET LRP1 LRP2 ARC PRKCA AGAP2 GABRA5	1.81e-04	858	111	14	GO:0030425
GeneOntologyCellularComponent	dendritic tree	ARHGAP32 MYH10 FRMPD4 SRC NUMA1 CKAP5 BRINP1 RET LRP1 LRP2 ARC PRKCA AGAP2 GABRA5	1.85e-04	860	111	14	GO:0097447
GeneOntologyCellularComponent	activin receptor complex	ACVR1C TGFBR1	4.13e-04	6	111	2	GO:0048179
GeneOntologyCellularComponent	myosin II complex	MYH10 MYH11 MYO18A	4.33e-04	28	111	3	GO:0016460
GeneOntologyCellularComponent	dense body	PIWIL2 SND1	5.77e-04	7	111	2	GO:0097433
GeneOntologyCellularComponent	somatodendritic compartment	ARHGAP32 KLHL24 MYH10 FRMPD4 SRC NUMA1 CKAP5 BRINP1 RET LRP1 LRP2 ARC PRKCA USH2A AGAP2 GABRA5	7.59e-04	1228	111	16	GO:0036477
Domain	-	HSPG2 LRP1B LRP1 LRP2 PRKCSH	7.99e-06	46	112	5	4.10.400.10
Domain	LDrepeatLR_classA_rpt	HSPG2 LRP1B LRP1 LRP2 PRKCSH	1.10e-05	49	112	5	IPR002172
Domain	LDLa	HSPG2 LRP1B LRP1 LRP2 PRKCSH	1.10e-05	49	112	5	SM00192
Domain	DUF5050	LRP1B LRP1	3.56e-05	2	112	2	IPR032485
Domain	DUF5050	LRP1B LRP1	3.56e-05	2	112	2	PF16472
Domain	P-loop_NTPase	RERG DNAH3 MYH10 MYH11 MYO18A CARD10 CHST1 FANCM ABCA7 EEF2 MDN1 MTIF2 DDX23 KIF13A MOV10 AGAP2	4.53e-05	848	112	16	IPR027417
Domain	Ldl_recept_b	LRP1B LRP1 LRP2	7.28e-05	14	112	3	PF00058
Domain	LDLRB	LRP1B LRP1 LRP2	7.28e-05	14	112	3	PS51120
Domain	LY	LRP1B LRP1 LRP2	9.06e-05	15	112	3	SM00135
Domain	LDLR_classB_rpt	LRP1B LRP1 LRP2	9.06e-05	15	112	3	IPR000033
Domain	LDLR_class-A_CS	HSPG2 LRP1B LRP1 LRP2	9.48e-05	40	112	4	IPR023415
Domain	Fatty_acid_desaturase	FADS3 FADS2	1.07e-04	3	112	2	IPR012171
Domain	Ldl_recept_a	HSPG2 LRP1B LRP1 LRP2	1.51e-04	45	112	4	PF00057
Domain	Myosin_tail_1	MYH10 MYH11 MYO18A	1.60e-04	18	112	3	PF01576
Domain	Myosin_tail	MYH10 MYH11 MYO18A	1.60e-04	18	112	3	IPR002928
Domain	6-blade_b-propeller_TolB-like	LRP1B LGI3 LRP1 LRP2	1.65e-04	46	112	4	IPR011042
Domain	Myosin-like_IQ_dom	MYH10 MYH11 MYO18A	1.90e-04	19	112	3	IPR027401
Domain	-	MYH10 MYH11 MYO18A	1.90e-04	19	112	3	4.10.270.10
Domain	LDLRA_1	HSPG2 LRP1B LRP1 LRP2	1.95e-04	48	112	4	PS01209
Domain	PX	ARHGAP32 SNX16 SNX30 SNX7	2.11e-04	49	112	4	PF00787
Domain	LDLRA_2	HSPG2 LRP1B LRP1 LRP2	2.11e-04	49	112	4	PS50068
Domain	PX	ARHGAP32 SNX16 SNX30 SNX7	2.28e-04	50	112	4	PS50195
Domain	-	ARHGAP32 SNX16 SNX30 SNX7	2.46e-04	51	112	4	3.30.1520.10
Domain	Phox	ARHGAP32 SNX16 SNX30 SNX7	2.66e-04	52	112	4	IPR001683
Domain	Myosin_S1_N	MYH10 MYH11	3.52e-04	5	112	2	IPR008989
Domain	cEGF	LRP1B LRP1 LRP2	4.94e-04	26	112	3	PF12662
Domain	cEGF	LRP1B LRP1 LRP2	4.94e-04	26	112	3	IPR026823
Domain	-	RERG DNAH3 MYO18A CARD10 CHST1 FANCM ABCA7 EEF2 MDN1 MTIF2 DDX23 MOV10 AGAP2	5.28e-04	746	112	13	3.40.50.300
Domain	Anoct_dimer	ANO4 ANO3	7.34e-04	7	112	2	PF16178
Domain	Anoct_dimer	ANO4 ANO3	7.34e-04	7	112	2	IPR032394
Domain	GS_dom	ACVR1C TGFBR1	7.34e-04	7	112	2	IPR003605
Domain	GS	ACVR1C TGFBR1	7.34e-04	7	112	2	PS51256
Domain	TGF_beta_GS	ACVR1C TGFBR1	7.34e-04	7	112	2	PF08515
Domain	GS	ACVR1C TGFBR1	7.34e-04	7	112	2	SM00467
Domain	FA_desaturase_dom	FADS3 FADS2	9.75e-04	8	112	2	IPR005804
Domain	FA_desaturase	FADS3 FADS2	9.75e-04	8	112	2	PF00487
Domain	Myosin_head_motor_dom	MYH10 MYH11 MYO18A	1.52e-03	38	112	3	IPR001609
Domain	MYOSIN_MOTOR	MYH10 MYH11 MYO18A	1.52e-03	38	112	3	PS51456
Domain	Myosin_head	MYH10 MYH11 MYO18A	1.52e-03	38	112	3	PF00063
Domain	MYSc	MYH10 MYH11 MYO18A	1.52e-03	38	112	3	SM00242
Domain	Anoctamin	ANO4 ANO3	1.55e-03	10	112	2	PF04547
Domain	Anoctamin	ANO4 ANO3	1.55e-03	10	112	2	IPR007632
Domain	Activin_recp	ACVR1C TGFBR1	1.55e-03	10	112	2	PF01064
Domain	Activin_recp	ACVR1C TGFBR1	1.55e-03	10	112	2	IPR000472
Domain	-	LRP1B LRP1 LRP2	1.64e-03	39	112	3	2.120.10.30
Domain	TGFB_receptor	ACVR1C TGFBR1	2.26e-03	12	112	2	IPR000333
Domain	Quinoprot_gluc/sorb_DH	LGI3 LRP1	2.26e-03	12	112	2	IPR011041
Domain	PX	SNX16 SNX30 SNX7	2.32e-03	44	112	3	SM00312
Domain	CYTOCHROME_B5_2	FADS3 FADS2	2.66e-03	13	112	2	PS50255
Domain	CYTOCHROME_B5_1	FADS3 FADS2	2.66e-03	13	112	2	PS00191
Domain	ATPase_dyneun-rel_AAA	DNAH3 MDN1	3.09e-03	14	112	2	IPR011704
Domain	Cyt-b5	FADS3 FADS2	3.09e-03	14	112	2	PF00173
Domain	-	FADS3 FADS2	3.09e-03	14	112	2	3.10.120.10
Domain	Cyt_B5-like_heme/steroid-bd	FADS3 FADS2	3.09e-03	14	112	2	IPR001199
Domain	Cyt-b5	FADS3 FADS2	3.09e-03	14	112	2	SM01117
Domain	AAA_5	DNAH3 MDN1	3.09e-03	14	112	2	PF07728
Domain	WW_DOMAIN_1	FRMPD4 WWP1 PLEKHA5	3.55e-03	51	112	3	PS01159
Domain	WW_DOMAIN_2	FRMPD4 WWP1 PLEKHA5	3.55e-03	51	112	3	PS50020
Domain	Myosin_N	MYH10 MYH11	3.56e-03	15	112	2	PF02736
Domain	Myosin_N	MYH10 MYH11	3.56e-03	15	112	2	IPR004009
Domain	WW_dom	FRMPD4 WWP1 PLEKHA5	3.75e-03	52	112	3	IPR001202
Domain	PH_dom-like	RANBP2 FRMPD4 ARHGAP15 TNS2 AGAP11 MTMR7 PLEKHA5 AGAP2	4.14e-03	426	112	8	IPR011993
Domain	EGF_1	HSPG2 HYAL1 LRP1B LRP1 LRP2 USH2A	4.38e-03	255	112	6	PS00022
Domain	EFTu-like_2	EEF2 MTIF2	5.12e-03	18	112	2	IPR004161
Domain	GTP_EFTU_D2	EEF2 MTIF2	5.12e-03	18	112	2	PF03144
Domain	G_TR_2	EEF2 MTIF2	5.12e-03	18	112	2	PS51722
Domain	Gal_Oxase/kelch_b-propeller	KLHL24 KBTBD2 KLHDC1	5.35e-03	59	112	3	IPR011043
Domain	TF_GTP-bd_dom	EEF2 MTIF2	5.70e-03	19	112	2	IPR000795
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	RANBP2 MYH10 MYH11 ZSWIM5 MTRES1 KTN1 NUMA1 MYO18A FAM47B CXXC1 NUP205 EEF2 MDN1 SND1 DDX23 ATG4C MYOM2 TOP1MT CCDC191 AGAP2	4.62e-08	1442	114	20	35575683
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ARHGAP32 RANBP2 MYH10 ZSCAN12 KTN1 SRC NUMA1 CKAP5 ZMYM2 EEF2 MDN1 LRP1 ARC PRKCA PLEKHA5 AGAP2	1.08e-07	963	114	16	28671696
Pubmed	A human MAP kinase interactome.	ARHGAP32 RANBP2 MYH10 MYH11 KTN1 SRC MYO18A ZMYM2 SETDB1 PLEKHA5 GAREM1	6.26e-07	486	114	11	20936779
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	RANBP2 EPPK1 NUMA1 CKAP5 ZMYM2 SETDB1 EEF2 MDN1 SND1	1.59e-06	332	114	9	32786267
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	NDUFB11 HSPG2 KTN1 APEX1 PTDSS2 LRP1B ABCA7 TMX2 TGFBR1 MYOF EEF2 LRP1 FADS2 UHRF1 PLEKHA5 PRKCSH	1.99e-06	1201	114	16	35696571
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RANBP2 MYH10 UBE4B KTN1 NUMA1 CKAP5 CXXC1 NUP205 EEF2 MDN1 SND1 DDX23 PRKCA PLEKHA5 RPL22L1 CORO7 MOV10	2.04e-06	1353	114	17	29467282
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	RANBP2 MYH10 EPPK1 KTN1 MYO18A CKAP5 APEX1 NUP205 SETDB1 MYOF EEF2 SND1 LRP1 FADS2 PRKCA PRKCSH ALDH5A1	2.34e-06	1367	114	17	32687490
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HSPG2 EPPK1 UBE4B WWP1 INPPL1 CARD10 ABCA7 SNX30 MYOF MDN1 SND1 ARC PCNX1 DISP2 GAREM1	3.42e-06	1105	114	15	35748872
Pubmed	DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells.	CKAP5 EEF2 MDN1 SND1	5.30e-06	35	114	4	24515614
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	HSPG2 ARHGAP32 IFFO1 WWP1 MYO18A TNS2 CXXC1 SETDB1 LRP2 FADS2 PLEKHA5	5.39e-06	608	114	11	16713569
Pubmed	LRP2 mediates folate uptake in the developing neural tube.	LRP1B LRP1 LRP2	5.55e-06	11	114	3	24639464
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	RANBP2 MYH10 EPPK1 NUMA1 ZMYM2 MDN1 UHRF1 DDX23 PRKCSH	6.38e-06	394	114	9	27248496
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MYH10 FRMPD4 UBE4B ZSWIM5 CKAP5 SETDB1 SEMA6D DISP2 FAIM2	8.28e-06	407	114	9	12693553
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	NDUFB11 RANBP2 ZSCAN12 UBE4B PDGFRB KTN1 CKAP5 ZMYM2 NUP205 TMX2 EEF2 FADS3 ICMT LRP1 FADS2	9.44e-06	1203	114	15	29180619
Pubmed	Ret-mediated mitogenesis requires Src kinase activity.	SRC RET	1.07e-05	2	114	2	10070972
Pubmed	Validation of PDGFRbeta and c-Src tyrosine kinases as tumor/vessel targets in patients with multiple myeloma: preclinical efficacy of the novel, orally available inhibitor dasatinib.	PDGFRB SRC	1.07e-05	2	114	2	18524994
Pubmed	Mitochondrial APE1/Ref-1 suppressed protein kinase C-induced mitochondrial dysfunction in mouse endothelial cells.	APEX1 PRKCA	1.07e-05	2	114	2	24861944
Pubmed	Striking differences of LDL receptor-related protein 1B expression in mouse and human.	LRP1B LRP1	1.07e-05	2	114	2	15963947
Pubmed	Translocation t(10;14)(q11.2:q22.1) fusing the kinetin to the RET gene creates a novel rearranged form (PTC8) of the RET proto-oncogene in radiation-induced childhood papillary thyroid carcinoma.	KTN1 RET	1.07e-05	2	114	2	10850414
Pubmed	Src family tyrosine kinases regulate adhesion-dependent tyrosine phosphorylation of 5'-inositol phosphatase SHIP2 during cell attachment and spreading on collagen I.	INPPL1 SRC	1.07e-05	2	114	2	12235291
Pubmed	Myosin heavy chain gene expression in normal and hyperplastic human prostate tissue.	MYH10 MYH11	1.07e-05	2	114	2	10906735
Pubmed	Platelet-derived growth factor receptor-beta (PDGFR-beta) activation promotes its association with the low density lipoprotein receptor-related protein (LRP). Evidence for co-receptor function.	PDGFRB LRP1	1.07e-05	2	114	2	15944146
Pubmed	Serine and threonine phosphorylation of the low density lipoprotein receptor-related protein by protein kinase Calpha regulates endocytosis and association with adaptor molecules.	LRP1 PRKCA	1.07e-05	2	114	2	15272003
Pubmed	Tyrosine 981, a novel ret autophosphorylation site, binds c-Src to mediate neuronal survival.	SRC RET	1.07e-05	2	114	2	14766744
Pubmed	Role of PKCα activation of Src, PI-3K/AKT, and ERK in EGF-stimulated proliferation of rat and human conjunctival goblet cells.	SRC PRKCA	1.07e-05	2	114	2	23882690
Pubmed	Human smooth muscle myosin heavy chain isoforms as molecular markers for vascular development and atherosclerosis.	MYH10 MYH11	1.07e-05	2	114	2	7916668
Pubmed	Prolyl hydroxylase-dependent modulation of eukaryotic elongation factor 2 activity and protein translation under acute hypoxia.	EGLN1 EEF2	1.07e-05	2	114	2	22308030
Pubmed	Constriction velocities of renal afferent and efferent arterioles of mice are not related to SMB expression.	MYH10 MYH11	1.07e-05	2	114	2	16316347
Pubmed	Identification of a MYO18A-PDGFRB fusion gene in an eosinophilia-associated atypical myeloproliferative neoplasm with a t(5;17)(q33-34;q11.2).	PDGFRB MYO18A	1.07e-05	2	114	2	19006078
Pubmed	Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.	LRP1 LRP2	1.07e-05	2	114	2	34445520
Pubmed	The PDGF receptor phosphorylates Tyr 138 in the c-Src SH3 domain in vivo reducing peptide ligand binding.	PDGFRB SRC	1.07e-05	2	114	2	9010229
Pubmed	A novel envelope mediated post entry restriction of murine leukaemia virus in human cells is Ref1/TRIM5α independent.	APEX1 TRIM5	1.07e-05	2	114	2	20929586
Pubmed	Association of the FADS gene cluster with coronary artery disease and plasma lipid concentrations in the northern Chinese Han population.	FADS3 FADS2	1.07e-05	2	114	2	28237083
Pubmed	Protein kinase C alpha-CARMA3 signaling axis links Ras to NF-kappa B for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells.	CARD10 PRKCA	1.07e-05	2	114	2	17724468
Pubmed	The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases.	INPPL1 SRC	1.07e-05	2	114	2	30228226
Pubmed	Molecular mechanism underlying the association of Coronin-7 with Golgi membranes.	SRC CORO7	1.07e-05	2	114	2	18581049
Pubmed	IL-1 beta induces proMMP-9 expression via c-Src-dependent PDGFR/PI3K/Akt/p300 cascade in rat brain astrocytes.	PDGFRB SRC	1.07e-05	2	114	2	18315570
Pubmed	Protein kinase C phosphorylates pp60src at a novel site.	SRC PRKCA	1.07e-05	2	114	2	2996780
Pubmed	Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.	LRP1B LRP1 LRP2	1.22e-05	14	114	3	15082773
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	MYH10 MYH11 EPPK1 KTN1 NUMA1 APEX1 MYOF EEF2 MDN1 SND1 PCNX1 PRKCSH	1.43e-05	807	114	12	30575818
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	MYH10 MYH11 EPPK1 FRMPD4 NUMA1 MYO18A EEF2 SND1 UHRF1 DDX23 RPL22L1 TOP1MT MOV10	1.46e-05	949	114	13	36574265
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	MYH10 MYH11 NUMA1 CKAP5 APEX1 MYOF DDX23 MOV10	1.72e-05	340	114	8	24332808
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	MYH10 PDGFRB DNAAF3 LRP1 LRP2	2.03e-05	100	114	5	25807483
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	UBE4B PDGFRB CKAP5 ZMYM2 LRP1B TRIM5 SETDB1 EEF2 MTIF2 LGI3 LRP1 LRP2 TNKS2 ALDH5A1 AGAP2	2.04e-05	1285	114	15	35914814
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	ARHGAP32 RANBP2 MYH10 FRMPD4 KTN1 MYO18A CKAP5 NDUFA6 LRP1B FADS2 PRKCA ALDH5A1 AGAP2 GABRA5	2.24e-05	1139	114	14	36417873
Pubmed	LINC00240 in the 6p22.1 risk locus promotes gastric cancer progression through USP10-mediated DDX21 stabilization.	KTN1 NUMA1 CKAP5	2.26e-05	17	114	3	37072811
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	MYH10 EPPK1 WWP1 CKAP5 ZMYM2 SEMA6D PRKCA MOV10	2.49e-05	358	114	8	32460013
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	RANBP2 MYH10 EPPK1 UBE4B NUMA1 EEF2 SND1 PRKCSH MOV10	2.89e-05	477	114	9	31300519
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	GCNT3 WWP1 SRC LRP1B MTMR7 MAPK12 LRP1 LRP2 PCSK7 PRKCA CES4A	2.94e-05	730	114	11	34857952
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	MYH10 MYO18A NUP205 MYOF EEF2 SND1 DDX23	3.04e-05	268	114	7	33024031
Pubmed	Placental expression of Fatty Acid Desaturases 1, 2 and 3 in selected pregnancy pathologies.	FADS3 FADS2	3.19e-05	3	114	2	36652541
Pubmed	Protein kinase C-alpha-mediated regulation of low-density lipoprotein receptor related protein and urokinase increases astrocytoma invasion.	LRP1 PRKCA	3.19e-05	3	114	2	17974965
Pubmed	Heterogeneous susceptibility of circulating SIV isolate capsids to HIV-interacting factors.	RANBP2 TRIM5	3.19e-05	3	114	2	23883001
Pubmed	Effects of h1-calponin ablation on the contractile properties of bladder versus vascular smooth muscle in mice lacking SM-B myosin.	MYH10 MYH11	3.19e-05	3	114	2	16973711
Pubmed	Catalytically inactive SHIP2 inhibits proliferation by attenuating PDGF signaling in 3T3-L1 preadipocytes.	PDGFRB INPPL1	3.19e-05	3	114	2	18814181
Pubmed	Association of gene polymorphisms in MYH11 and TGF-β signaling with the susceptibility and clinical outcomes of DeBakey type III aortic dissection.	MYH11 TGFBR1	3.19e-05	3	114	2	34729648
Pubmed	cDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family.	FADS3 FADS2	3.19e-05	3	114	2	10860662
Pubmed	Activation of Endogenous Retroviruses in Dnmt1(-/-) ESCs Involves Disruption of SETDB1-Mediated Repression by NP95 Binding to Hemimethylated DNA.	SETDB1 UHRF1	3.19e-05	3	114	2	27151458
Pubmed	Protein kinase Cα and Src kinase support human prostate-distributed dihydrotestosterone-metabolizing UDP-glucuronosyltransferase 2B15 activity.	SRC PRKCA	3.19e-05	3	114	2	22532564
Pubmed	Local and global dynamics of the basement membrane during branching morphogenesis require protease activity and actomyosin contractility.	HSPG2 MYH10	3.19e-05	3	114	2	25158168
Pubmed	Low density lipoprotein receptor-related protein 1 (LRP1) controls endocytosis and c-CBL-mediated ubiquitination of the platelet-derived growth factor receptor beta (PDGFR beta).	PDGFRB LRP1	3.19e-05	3	114	2	15753096
Pubmed	v-Src induces Shc binding to tyrosine 63 in the cytoplasmic domain of the LDL receptor-related protein 1.	SRC LRP1	3.19e-05	3	114	2	12789267
Pubmed	Umbilical cord PUFA are determined by maternal and child fatty acid desaturase (FADS) genetic variants in the Avon Longitudinal Study of Parents and Children (ALSPAC).	FADS3 FADS2	3.19e-05	3	114	2	22877655
Pubmed	Activation of protein kinase C alpha is necessary for sorting the PDGF beta-receptor to Rab4a-dependent recycling.	PDGFRB PRKCA	3.19e-05	3	114	2	19369415
Pubmed	LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation.	PDGFRB LRP1	3.19e-05	3	114	2	19742316
Pubmed	FADS gene polymorphisms in Koreans: association with ω6 polyunsaturated fatty acids in serum phospholipids, lipid peroxides, and coronary artery disease.	FADS3 FADS2	3.19e-05	3	114	2	21040914
Pubmed	Genetic variants in desaturase gene, erythrocyte fatty acids, and risk for type 2 diabetes in Chinese Hans.	FADS3 FADS2	3.19e-05	3	114	2	24985009
Pubmed	PDGF receptor activation induces p120-catenin phosphorylation at serine 879 via a PKCalpha-dependent pathway.	PDGFRB PRKCA	3.19e-05	3	114	2	18950621
Pubmed	Crosstalk between protein kinase C α and transforming growth factor β signaling mediated by Runx2 in intestinal epithelial cells.	TGFBR1 PRKCA	3.19e-05	3	114	2	36791912
Pubmed	Association of polyunsaturated fatty acids in breast milk with fatty acid desaturase gene polymorphisms among Chinese lactating mothers.	FADS3 FADS2	3.19e-05	3	114	2	27269715
Pubmed	TNF-alpha induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NF-kappaB/p300 binding in human tracheal smooth muscle cells.	PDGFRB SRC	3.19e-05	3	114	2	17158602
Pubmed	Functional interaction of protein kinase Calpha with the tyrosine kinases Syk and Src in human platelets.	SRC PRKCA	3.19e-05	3	114	2	15583006
Pubmed	The LDL receptor-related protein 1 (LRP1) regulates the PDGF signaling pathway by binding the protein phosphatase SHP-2 and modulating SHP-2- mediated PDGF signaling events.	PDGFRB LRP1	3.19e-05	3	114	2	23922991
Pubmed	Protein kinase Calpha activates c-Src and induces podosome formation via AFAP-110.	SRC PRKCA	3.19e-05	3	114	2	15314167
Pubmed	Src-dependent autophagic degradation of Ret in FAK-signalling-defective cancer cells.	SRC RET	3.19e-05	3	114	2	22732841
Pubmed	Platelet-derived growth factor β-receptor, transforming growth factor β type I receptor, and CD44 protein modulate each other's signaling and stability.	PDGFRB TGFBR1	3.19e-05	3	114	2	24860093
Pubmed	Maintenance DNA methylation in pre-meiotic germ cells regulates meiotic prophase by facilitating homologous chromosome pairing.	SETDB1 UHRF1	3.19e-05	3	114	2	33998651
Pubmed	MT1-MMP promotes vascular smooth muscle dedifferentiation through LRP1 processing.	PDGFRB LRP1	3.19e-05	3	114	2	19066283
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	PDGFRB WWP1 RET ACVR1C CXXC1 SETDB1 ANAPC2 PRKCA	3.26e-05	372	114	8	22939624
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	ARHGAP32 UBE4B SRC AGAP11 ARC PRKCA AGAP2	4.11e-05	281	114	7	28706196
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	RANBP2 NUMA1 ZMYM2 EEF2 ANAPC2 UHRF1 PRKCA PLEKHA5 KIF13A	4.36e-05	503	114	9	16964243
Pubmed	MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.	LRP1B LRP1 LRP2	4.37e-05	21	114	3	21337463
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	RANBP2 MYH10 MYH11 EPPK1 MYO18A TRIM5 EEF2 MDN1 PRKCSH MOV10	5.56e-05	647	114	10	26618866
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	MYH10 MYH11 NUMA1 MYO18A CKAP5 MYOF	5.65e-05	202	114	6	33005030
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	RANBP2 MYH10 MYH11 NUMA1 NUP205 EEF2	5.65e-05	202	114	6	24639526
Pubmed	Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts.	ARHGAP15 MTIF2 LRP2	5.79e-05	23	114	3	20468071
Pubmed	Targeted disruption of the histone lysine 79 methyltransferase Dot1L in nephron progenitors causes congenital renal dysplasia.	MYH11 PDGFRB RET	5.79e-05	23	114	3	33315499
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	HSPG2 NUMA1 CKAP5 ZMYM2 EEF2 SND1	5.80e-05	203	114	6	22083510
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RANBP2 MYH10 EPPK1 NUMA1 CKAP5 NUP205 MDN1 SND1 DDX23 MOV10	6.01e-05	653	114	10	22586326
Pubmed	MLLT11/AF1q boosts oncogenic STAT3 activity through Src-PDGFR tyrosine kinase signaling.	PDGFRB SRC	6.36e-05	4	114	2	27259262
Pubmed	Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.	LRP1 LRP2	6.36e-05	4	114	2	12413896
Pubmed	FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population.	FADS3 FADS2	6.36e-05	4	114	2	20562440
Pubmed	Targeting the histone demethylase PHF8-mediated PKCα-Src-PTEN axis in HER2-negative gastric cancer.	SRC PRKCA	6.36e-05	4	114	2	32958674
Pubmed	Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.	LRP1 LRP2	6.36e-05	4	114	2	7775583
Pubmed	TRIB3-EGFR interaction promotes lung cancer progression and defines a therapeutic target.	WWP1 PRKCA	6.36e-05	4	114	2	32694521
Pubmed	A heterodimeric SNX4--SNX7 SNX-BAR autophagy complex coordinates ATG9A trafficking for efficient autophagosome assembly.	SNX30 SNX7	6.36e-05	4	114	2	32513819
Pubmed	A signaling cascade mediated by ceramide, src and PDGFRβ coordinates the activation of the redox-sensitive neutral sphingomyelinase-2 and sphingosine kinase-1.	PDGFRB SRC	6.36e-05	4	114	2	23651497
Pubmed	Cytogenetically cryptic ZMYM2-FLT3 and DIAPH1-PDGFRB gene fusions in myeloid neoplasms with eosinophilia.	PDGFRB ZMYM2	6.36e-05	4	114	2	28751768
Pubmed	Src activates HIF-1α not through direct phosphorylation of HIF-1α specific prolyl-4 hydroxylase 2 but through activation of the NADPH oxidase/Rac pathway.	EGLN1 SRC	6.36e-05	4	114	2	21335603
Pubmed	FLJ10261 gene, located within the CCND1-EMS1 locus on human chromosome 11q13, encodes the eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products.	ANO4 ANO3	6.36e-05	4	114	2	12739008
Interaction	SHC1 interactions	ARHGAP32 MYH10 MYH11 PDGFRB INPPL1 SRC RET EEF2 LRP1 PRKCA MOV10 GAREM1	1.00e-06	362	114	12	int:SHC1
Interaction	RAC1 interactions	ARHGAP32 ARHGAP15 PDGFRB INPPL1 KTN1 SRC MYO18A BRINP1 NUP205 TGFBR1 MYOF EEF2 MDN1 SEMA6D ICMT LRP2 PRKCA PLEKHA5 ADGRL2 AGAP2	1.98e-06	1063	114	20	int:RAC1
Interaction	ITGB3 interactions	MYH10 PDGFRB SRC TNS2 MYOF MDN1 PRKCA MOV10	5.60e-06	170	114	8	int:ITGB3
Interaction	HSP90AA1 interactions	HSPG2 PDGFRB WWP1 KTN1 EGLN1 SRC NUMA1 PTDSS2 PIWIL2 RET ACVR1C CXXC1 TGFBR1 SETDB1 EEF2 SND1 ANAPC2 LRP1 UHRF1 PRKCA PRKCSH	7.33e-06	1263	114	21	int:HSP90AA1
Interaction	GRIN2A interactions	ARHGAP32 SRC PIGA LRP1 PRKCA AGAP2	1.47e-05	93	114	6	int:GRIN2A
GeneFamily	Low density lipoprotein receptors	LRP1B LRP1 LRP2	2.97e-05	13	87	3	634
GeneFamily	Sorting nexins\|PX-BAR domain containing	SNX16 SNX30 SNX7	3.59e-04	29	87	3	754
GeneFamily	Type 1 receptor serine/threonine kinases	ACVR1C TGFBR1	4.73e-04	7	87	2	345
GeneFamily	Fatty acid desaturases	FADS3 FADS2	6.29e-04	8	87	2	553
GeneFamily	Tudor domain containing	SETDB1 SND1 UHRF1	7.43e-04	37	87	3	780
GeneFamily	Anoctamins	ANO4 ANO3	1.00e-03	10	87	2	865
GeneFamily	Sorting nexins\|PX-BAR domain containing	SNX30 SNX7	1.46e-03	12	87	2	1290
GeneFamily	Myosin heavy chains	MYH10 MYH11	2.31e-03	15	87	2	1098
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP11 AGAP2	2.97e-03	17	87	2	1291
Coexpression	FAN_EMBRYONIC_CTX_OLIG	ANO4 CLN8 KLHL24 UBE4B KTN1 TNS2 SNX30 MTMR7 LGI3 PCSK7 ATG4C PRKCSH KIF13A FAIM2 GAREM1	9.89e-07	754	114	15	M39037
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RERG MYH11 PDGFRB FADS3 MDN1 CES4A AGAP2	3.74e-07	177	114	7	7c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RERG MYH11 PDGFRB FADS3 MDN1 CES4A AGAP2	3.74e-07	177	114	7	e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	NUMA1 MYO18A LRP1B MDN1 PRKCA KIF13A ALDH5A1	3.74e-07	177	114	7	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 SLC35F1 LRP1B LRP2 MYOM2 USH2A ANO3	4.86e-07	184	114	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 SLC35F1 LRP1B LRP2 MYOM2 USH2A ANO3	4.86e-07	184	114	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 SLC35F1 LRP1B LRP2 MYOM2 USH2A ANO3	4.86e-07	184	114	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RERG ARHGAP32 MYH11 PDGFRB ZSWIM5 MYOF SEMA6D	4.86e-07	184	114	7	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RERG MYH11 FRMPD4 PDGFRB SLC35F1 MYOF SEMA6D	5.41e-07	187	114	7	a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCell	Tracheal-10x5prime-Stromal-Pericyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	RERG MYH11 PDGFRB SLC35F1 FADS3 SEMA6D ANO3	8.22e-07	199	114	7	cefc3b50f65e95da850e4720c7b44bf584073491
ToppCell	Tracheal-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	RERG MYH11 PDGFRB SLC35F1 FADS3 SEMA6D ANO3	8.22e-07	199	114	7	aaa460c389cd6d38a13ba1a446f91a94f9573ad8
ToppCell	LPS_only-Mesenchymal_myocytic\|LPS_only / Treatment groups by lineage, cell group, cell type	ANO4 RERG MYH10 MYH11 PDGFRB SLC35F1 MYOF	8.50e-07	200	114	7	8bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RERG MYH10 MYH11 PDGFRB TGFBR1 ANO3	5.99e-06	175	114	6	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 ARHGAP32 EGLN1 FADS3 MAPK12 ADGRL2	7.26e-06	181	114	6	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-MEP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MYH10 DNAAF3 EEF2 LRP2 RPL22L1 GABRA5	7.26e-06	181	114	6	ee207ea171e2ffc22a7f850be57bb118a87e0f81
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	RERG MYH10 MYH11 PDGFRB MYOF KIF13A	7.73e-06	183	114	6	818fd886e0188091310825f9145fa53328f2c979
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	HSPG2 MYH10 TNS2 CARD10 RET DIPK2B	8.48e-06	186	114	6	a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB TNS2 RET LRP1 PRKCA ANO3	8.74e-06	187	114	6	d591a3c216997663ab77710fed0d230ffc37e41a
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RERG MYH11 FRMPD4 PDGFRB SLC35F1 SEMA6D	8.74e-06	187	114	6	fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB TNS2 RET LRP1 PRKCA ANO3	8.74e-06	187	114	6	d1dc8c9a2c2cd10c640257161a75e7730ec5bb41
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB TNS2 RET LRP1 PRKCA ANO3	8.74e-06	187	114	6	ac8e092b37e042975e2ee057d3f7c6821e58e8b5
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RERG MYH11 PDGFRB TNS2 SEMA6D ADGRL2	9.01e-06	188	114	6	ee151792c7ac9afe820f1a281c6dab383799f358
ToppCell	Mesenchymal-pericyte_cell\|World / Lineage, Cell type, age group and donor	RERG MYH11 FRMPD4 PDGFRB SLC35F1 SEMA6D	9.29e-06	189	114	6	d7ed96add29f219183c802895fbff519b627f635
ToppCell	Hippocampus-Neuronal-Excitatory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CHST1 ACVR1C ARC ANO3 AGAP2 GABRA5	9.29e-06	189	114	6	4b90d181eb0a42814eeb23bc82e52fd3a12392a7
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANO4 RERG MYH11 PDGFRB SLC35F1 MYOF	9.86e-06	191	114	6	08042952431ca1a6fd7dfc13f36eb28643979598
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANO4 RERG MYH11 PDGFRB SLC35F1 MYOF	9.86e-06	191	114	6	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	Mesenchymal-vascular_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	RERG MYH10 MYH11 PDGFRB SLC35F1 MYOM2	9.86e-06	191	114	6	fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RERG ARHGAP15 PDGFRB LRP1 FAIM2 ANO3	1.02e-05	192	114	6	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RERG MYH11 FRMPD4 PDGFRB SLC35F1 MYOM2	1.02e-05	192	114	6	55f95454399fd533df75db06584eaa48d6ee3830
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RERG MYH11 PDGFRB MTMR7 FADS3 SEMA6D	1.02e-05	192	114	6	88472b99970ba0decbf87164fc241a1c77b3b389
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RERG ARHGAP15 PDGFRB LRP1 FAIM2 ANO3	1.02e-05	192	114	6	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	LAM-LAM-LAM+\|LAM / Condition, Lineage and Cell class	ANO4 RERG MYH11 SLC35F1 FAIM2 ANO3	1.08e-05	194	114	6	4ba73a9145ed44896e359f6df9c1f32bbe24a189
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RERG MYH11 PDGFRB MTMR7 FADS3 SEMA6D	1.08e-05	194	114	6	52ecec2618c3bb5fdd7fb06b5a40bd6f0aedfe1d
ToppCell	LAM-LAM\|LAM / Condition, Lineage and Cell class	ANO4 RERG MYH11 SLC35F1 FAIM2 ANO3	1.08e-05	194	114	6	4c6561a64711c72c4ef4a3e67c41d2e8d31fba57
ToppCell	11.5-Distal-Mesenchymal-Pericyte\|Distal / Age, Tissue, Lineage and Cell class	RERG MYH11 PDGFRB SLC35F1 RHBDL2 PRKCA	1.08e-05	194	114	6	08701590496cf85ff790e54a81493c61177e76ff
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ANO4 RERG MYH11 FRMPD4 SLC35F1 SEMA6D	1.08e-05	194	114	6	67f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 RERG MYH10 TGFBR1 LRP1 FAIM2	1.11e-05	195	114	6	841fde528ecb293e07b5e00e499d1e9f0b0dce14
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RERG MYH11 PDGFRB SLC35F1 LRP1 PRKCA	1.11e-05	195	114	6	d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANO4 RERG MYH10 MYH11 PDGFRB ANO3	1.18e-05	197	114	6	6d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HYAL1 ABCA7 SNX30 MYOF LGI3 FADS2	1.21e-05	198	114	6	85215015bb86ada0e871c413a4ecdc903a3785ca
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HYAL1 ABCA7 SNX30 MYOF LGI3 FADS2	1.21e-05	198	114	6	38349e42a3f1fb700ff6dfd89c4bf5ff97f1a3e9
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ANO4 MYH10 MYH11 PDGFRB MYOF LRP1	1.25e-05	199	114	6	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	RERG MYH11 PDGFRB SLC35F1 MYOF SEMA6D	1.28e-05	200	114	6	b22cae282591d8dead9869c2adbb9632615f50f7
ToppCell	Control_saline-Mesenchymal_myocytic\|Control_saline / Treatment groups by lineage, cell group, cell type	ANO4 RERG MYH11 PDGFRB MYOF LRP1	1.28e-05	200	114	6	5ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ANO4 RERG MYH10 MYH11 PDGFRB MYOF	1.28e-05	200	114	6	67dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte\|LPS_only / Treatment groups by lineage, cell group, cell type	RERG MYH11 PDGFRB SLC35F1 MYOF SEMA6D	1.28e-05	200	114	6	8c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	ANO4 RERG MYH10 MYH11 PDGFRB LRP1	1.28e-05	200	114	6	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	Bronchial-10x5prime-Stromal-Pericyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	RERG MYH11 PDGFRB TNS2 SLC35F1 SEMA6D	1.28e-05	200	114	6	362706445edb33b313684efe50b1f44f5f816e67
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte\|Control_saline / Treatment groups by lineage, cell group, cell type	RERG MYH11 PDGFRB SLC35F1 SEMA6D LRP1	1.28e-05	200	114	6	cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCell	LPS_IL1RA-Mesenchymal_myocytic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ANO4 RERG MYH11 PDGFRB SLC35F1 MYOF	1.28e-05	200	114	6	77631c471cc5d453a749784f838cfa6408caf09b
ToppCell	Pericytes-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	RERG MYH10 MYH11 PDGFRB CCDC191	4.22e-05	150	114	5	dbc202bd6db4fb5c8b2abd1200e074a2a9e63a59
ToppCell	cellseq2-Epithelial-Epithelial_Neuro-Secretory-Ionocyte\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANO4 RET RHBDL2 CORO7 FAIM2	5.74e-05	160	114	5	9049707a4487f2337a17976ceb5fbd8815ab9e1d
ToppCell	cellseq2-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANO4 RET RHBDL2 CORO7 FAIM2	5.74e-05	160	114	5	f2cfec54cf48a655f473b830be7d141c54b521ff
ToppCell	cellseq2-Epithelial-Epithelial_Neuro-Secretory\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANO4 RET RHBDL2 CORO7 FAIM2	5.74e-05	160	114	5	0eb50b3c494e1b65d40104b3b5411b57bb72b959
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	RERG MYH10 MYH11 EPPK1 PDGFRB	5.91e-05	161	114	5	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYH11 PDGFRB SLC35F1 MYOM2 ANO3	6.64e-05	165	114	5	9de841c1c95967c562720feba930246debc626fd
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYH11 PDGFRB SLC35F1 MYOM2 ANO3	6.64e-05	165	114	5	a612a7d3a5415ecacc3df8fbff0ce498f982aad0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYH11 PDGFRB SLC35F1 MYOM2 ANO3	6.64e-05	165	114	5	cdc94a640ec01c6892521bcd6f0ee0a66ff23866
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRMPD4 MTRES1 MTIF2 RPL22L1 MOV10	6.83e-05	166	114	5	43f84d3cd58e93ce00c241656c4cba27604b4932
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CHST1 ACVR1C ARC GAREM1 GABRA5	7.23e-05	168	114	5	6db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCell	facs-Marrow-T_cells-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOF FADS3 LGI3 FADS2 ALDH5A1	7.43e-05	169	114	5	2a35846b0e0be0a19a5a04a86cbd72ce65257c8a
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HSPG2 ARHGAP32 PDGFRB LRP1B LRP1	7.64e-05	170	114	5	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INPPL1 DNAAF3 MYOF SEMA6D LRP1	7.64e-05	170	114	5	067657ca7fcf5a0ffbd168b5c4609a30ca508f22
ToppCell	Control-Fibroblasts-Pericytes\|Control / group, cell type (main and fine annotations)	RERG MYH11 PDGFRB SEMA6D ADGRL2	7.86e-05	171	114	5	080003f698f867935c2bfc55d241d3650f45a0ab
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5_RORB_LINC01202\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP15 PDGFRB SEMA6D ANO3 GABRA5	8.08e-05	172	114	5	18bdf34e1b94dcb1daf00c533e3ce1a8d67fcc0e
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP15 PDGFRB SEMA6D ANO3 GABRA5	8.08e-05	172	114	5	41ddfb316429efef5f3fa0b0621ced383d9206f0
ToppCell	Adult-Mesenchymal-pericyte_cell-D175\|Adult / Lineage, Cell type, age group and donor	RERG MYH11 PDGFRB SEMA6D ADGRL2	8.30e-05	173	114	5	fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP15 ACVR1C RHBDL2 MAPK12 AGAP2	8.30e-05	173	114	5	53e97835d7a518c278e7b90a0734eb0095d6aa33
ToppCell	droplet-Lung-1m-Hematologic-myeloid-Basophil/Mast_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP15 ACVR1C RHBDL2 MAPK12 AGAP2	8.30e-05	173	114	5	117163c5cd2b7aaa1c0682c8ac44b4249df4d2f8
ToppCell	facs-Lung-Endomucin-24m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRB SRC FADS3 FADS2 GAREM1	8.30e-05	173	114	5	a37f38478473290fe35aea8684befc3bf95b161f
ToppCell	droplet-Lung-LUNG-1m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP15 ACVR1C RHBDL2 MAPK12 AGAP2	8.30e-05	173	114	5	889a880de5fc19d26b82cfef3067869a28ef17ca
ToppCell	droplet-Lung-1m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP15 ACVR1C RHBDL2 MAPK12 AGAP2	8.30e-05	173	114	5	01df9baeedf30e3a4891738554cdd300394dbb96
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYH11 PDGFRB SLC35F1 FADS3 MYOM2	8.53e-05	174	114	5	015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	ANO4 PDGFRB LRP1B LRP1 FAIM2	9.00e-05	176	114	5	2e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACVR1C ABCA7 MYOF LRP1 UHRF1	9.00e-05	176	114	5	450c25ec5eeb65425f904e0a25aaafdf5682ef9c
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	ANO4 PDGFRB LRP1B LRP1 FAIM2	9.00e-05	176	114	5	f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RERG MYH11 PDGFRB SLC35F1 SEMA6D	9.49e-05	178	114	5	185b44700f06ec58b3c09c80520502166c965fd6
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RERG MYH11 PDGFRB SLC35F1 MYOM2	9.49e-05	178	114	5	066dbc4cc2083c549d98122ed44707127f34d582
ToppCell	COVID-19-kidney-vSMC/Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RERG MYH11 PDGFRB MTMR7 MYOM2	9.75e-05	179	114	5	111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RERG ARHGAP32 MYH11 PDGFRB FADS3	9.75e-05	179	114	5	bfc226bcf0b93525992344f968268a261d86fcbf
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RERG ARHGAP32 MYH11 PDGFRB FADS3	9.75e-05	179	114	5	36ad18f52e175ab636ceaa3be81212fa362c96c1
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ARHGAP32 ARC ADGRL2 ANO3 GABRA5	1.03e-04	181	114	5	58f76bb9ea1518c2b629a0256a3f6595a9278152
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RERG MYH11 PDGFRB TNS2 SEMA6D	1.03e-04	181	114	5	451b87ac95154bb80018b8dd245b4a6389d81411
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	DNAH3 MYH11 BRINP1 LRP2 USH2A	1.03e-04	181	114	5	c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_IL7R\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RERG CHST1 TGFBR1 SEMA6D MYOM2	1.03e-04	181	114	5	b9fe3833a6a56b9fbe5c257393fdbea5bf8ac4a3
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RERG MYH11 PDGFRB SEMA6D PRKCA	1.08e-04	183	114	5	8a799807fbf24456a9811e0c64068187940a2f71
ToppCell	facs-Heart-RA-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RERG PDGFRB ZSWIM5 FADS3 AGAP2	1.08e-04	183	114	5	0f02136359787bd78146617990968baa47a65d86
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RERG MYH11 PDGFRB SLC35F1 ANO3	1.08e-04	183	114	5	667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCell	facs-Heart-RA-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RERG PDGFRB ZSWIM5 FADS3 AGAP2	1.08e-04	183	114	5	2f0dcc65ad4d90ef946919b4462280fdd20c5ea0
ToppCell	Adult-Mesenchymal-pericyte_cell-D122\|Adult / Lineage, Cell type, age group and donor	RERG MYH11 PDGFRB TNS2 ADGRL2	1.08e-04	183	114	5	fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 CTSF RET FADS3 FADS2	1.08e-04	183	114	5	351d575339038bd4a66f408da518c567444208e8
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	RERG MYH10 MYH11 PDGFRB MYOF	1.08e-04	183	114	5	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RERG MYH11 PDGFRB SEMA6D PRKCA	1.11e-04	184	114	5	689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCell	droplet-Lung-30m-Mesenchymal-myofibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RERG ARHGAP32 MYH11 PDGFRB FADS3	1.11e-04	184	114	5	55dde9c4eebac2a33788c1ff1d8fe312d150fad4
ToppCell	normal_Lung-Endothelial_cells-Tumor_ECs\|normal_Lung / Location, Cell class and cell subclass	HSPG2 FRMPD4 CARD10 CHST1 DIPK2B	1.11e-04	184	114	5	7ee98acda030366ac6cf3890a6d93fd0426712ed
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP15 PDGFRB LRP1 FAIM2 ANO3	1.11e-04	184	114	5	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	droplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RERG ARHGAP32 MYH11 PDGFRB FADS3	1.11e-04	184	114	5	7128a2be291544d3df3ed6c80f21ddda8437dcba
ToppCell	droplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RERG ARHGAP32 MYH11 PDGFRB FADS3	1.11e-04	184	114	5	d14238f7b0b55a4c8d7040bea854bd221a66ac30
ToppCell	Posterior_cortex-Neuronal-Excitatory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ARHGAP32 BRINP1 ARC ANO3 GABRA5	1.11e-04	184	114	5	25ccf08a8a26d7e7827b6357f33a53aaf423577d
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RERG MYH11 PDGFRB MYOF SEMA6D	1.11e-04	184	114	5	102b6f621a5b551e622f97b12d787c080b052a72
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYH11 ARHGAP15 PDGFRB SLC35F1 ANO3	1.14e-04	185	114	5	7092436b4db90289516ed130ade596e3021cffaf
Drug	H-89, Dihydrochloride; Up 200; 0.5uM; PC3; HT_HG-U133A	HSPG2 KLHL24 CTSF MYH10 SETDB1 MYOF ANAPC2 RASSF8 ALDH5A1	5.90e-07	194	114	9	6921_UP
Drug	PtdIns(3)P	ARHGAP32 INPPL1 EGLN1 SRC SNX16 EEF2 MTMR7 ICMT	2.86e-06	175	114	8	CID000643964
Drug	Doxepin hydrochloride [1229-29-4]; Up 200; 12.6uM; MCF7; HT_HG-U133A	KLHL24 NUMA1 ZMYM2 FADS3 FCAR MAPK12 SND1 ADGRL2	6.85e-06	197	114	8	7415_UP
Disease	level of Sterol ester (27:1/20:3) in blood serum	MYH11 FADS3 FADS2	5.07e-05	19	113	3	OBA_2045199
Disease	Heschl's gyrus morphology measurement	PRKCA PCNX1 DISP2 MYOM2	5.17e-05	53	113	4	EFO_0005852
Disease	level of Phosphatidylinositol (18:0_20:4) in blood serum	FADS3 FADS2 ATG4C	9.16e-05	23	113	3	OBA_2045158
Disease	level of Phosphatidylcholine (16:0_18:0) in blood serum	FADS3 FADS2	2.16e-04	6	113	2	OBA_2045069
Disease	level of Phosphatidylcholine (16:1_20:4) in blood serum	FADS3 FADS2	2.16e-04	6	113	2	OBA_2045084
Disease	resting heart rate	MYH11 EPPK1 SLC35F1 FADS2 GAREM1	2.78e-04	149	113	5	EFO_0004351
Disease	level of Phosphatidylcholine (O-18:2_18:1) in blood serum	FADS3 FADS2	3.01e-04	7	113	2	OBA_2045133
Disease	lysophosphatidylcholine 22:4 measurement	FADS3 FADS2	3.01e-04	7	113	2	EFO_0021461
Disease	phosphatidylcholine 35:5 measurement	FADS3 FADS2	3.01e-04	7	113	2	EFO_0021472
Disease	cholesteryl ester 24:4 measurement	TNS2 FADS2	3.01e-04	7	113	2	EFO_0021447
Disease	level of Phosphatidylethanolamine (O-18:1_18:2) in blood serum	FADS3 FADS2	4.01e-04	8	113	2	OBA_2045147
Disease	phosphatidylcholine 39:5 measurement	FADS3 FADS2	5.14e-04	9	113	2	EFO_0021476
Disease	level of Phosphatidylcholine (18:2_20:1) in blood serum	FADS3 FADS2	5.14e-04	9	113	2	OBA_2045107
Disease	level of Phosphatidylcholine (O-18:0_20:4) in blood serum	FADS3 FADS2	5.14e-04	9	113	2	OBA_2045127
Disease	level of Phosphatidylcholine (O-18:1_18:2) in blood serum	FADS3 FADS2	5.14e-04	9	113	2	OBA_2045129
Disease	level of Phosphatidylcholine (O-18:1_20:3) in blood serum	FADS3 FADS2	5.14e-04	9	113	2	OBA_2045130
Disease	level of Phosphatidylcholine (16:0_20:5) in blood serum	FADS3 FADS2	5.14e-04	9	113	2	OBA_2045077
Disease	level of Phosphatidylcholine (18:0_20:5) in blood serum	FADS3 FADS2	5.14e-04	9	113	2	OBA_2045095
Disease	phosphatidylethanolamine measurement	GCNT3 FADS3 SEMA6D FADS2 USH2A	5.51e-04	173	113	5	EFO_0010228
Disease	information processing speed, cognitive function measurement	CLN8 KTN1	6.41e-04	10	113	2	EFO_0004363, EFO_0008354
Disease	Familial thoracic aortic aneurysm and aortic dissection	MYH11 TGFBR1	6.41e-04	10	113	2	cv:C4707243
Disease	level of Phosphatidylethanolamine (O-18:1_20:4) in blood serum	FADS3 FADS2	6.41e-04	10	113	2	OBA_2045148
Disease	cholesteryl ester 22:4 measurement	FADS3 FADS2	6.41e-04	10	113	2	EFO_0021443
Disease	cholesteryl ester 22:5 measurement	FADS3 FADS2	6.41e-04	10	113	2	EFO_0021444
Disease	level of Phosphatidylcholine (16:0_20:3) in blood serum	MYH11 FADS2	6.41e-04	10	113	2	OBA_2045075
Disease	urate measurement	RERG DNAH3 CHST1 CXXC1 FADS3 LRP1 LRP2 FADS2 UHRF1 ADGRL2 FAIM2	6.57e-04	895	113	11	EFO_0004531
Disease	QRS complex, QRS duration	SLC35F1 FADS2 PRKCA	6.90e-04	45	113	3	EFO_0005054, EFO_0005055
Disease	level of Phosphatidylcholine (O-16:1_20:4) in blood serum	FADS3 FADS2	7.82e-04	11	113	2	OBA_2045123
Disease	lysophosphatidylcholine 20:2 measurement	FADS3 FADS2	7.82e-04	11	113	2	EFO_0021458
Disease	cholesteryl ester 20:3 measurement	MYH11 FADS3 FADS2	8.86e-04	49	113	3	EFO_0010347
Disease	cholesteryl ester 20:2 measurement	FADS3 FADS2	9.36e-04	12	113	2	EFO_0021440
Disease	cholesteryl ester 24:5 measurement	TNS2 FADS2	9.36e-04	12	113	2	EFO_0021448
Disease	creatinine measurement, glomerular filtration rate	RERG KBTBD2 LRP2 ADGRL2	1.08e-03	117	113	4	EFO_0004518, EFO_0005208
Disease	level of Phosphatidylcholine (O-16:0_20:4) in blood serum	FADS3 FADS2	1.10e-03	13	113	2	OBA_2045116
Disease	level of Phosphatidylcholine (16:0_18:3) in blood serum	FADS3 FADS2	1.10e-03	13	113	2	OBA_2045072
Disease	household income	ARHGAP15 BRINP1 LRP1B DNAAF3 SEMA6D PCNX1	1.14e-03	304	113	6	EFO_0009695
Disease	level of Phosphatidylcholine (18:1_18:2) in blood serum	FADS2 ATG4C	1.28e-03	14	113	2	OBA_2045100
Disease	level of Phosphatidylcholine (18:1_20:2) in blood serum	FADS3 FADS2	1.28e-03	14	113	2	OBA_2045102
Disease	diacylglycerol 38:4 measurement	FADS3 FADS2	1.28e-03	14	113	2	EFO_0020066
Disease	cis/trans-18:2 fatty acid measurement, trans fatty acid measurement	FADS3 FADS2	1.48e-03	15	113	2	EFO_0006821, EFO_0006824
Disease	oleoyl-arachidonoyl-glycerol (18:1/20:4) [2] measurement	FADS3 FADS2	1.48e-03	15	113	2	EFO_0800508
Disease	level of Phosphatidylcholine (O-18:1_20:4) in blood serum	FADS3 FADS2	1.48e-03	15	113	2	OBA_2045131
Disease	lipid metabolism disorder (implicated_via_orthology)	FADS3 FADS2	1.48e-03	15	113	2	DOID:3146 (implicated_via_orthology)
Disease	hypertension (implicated_via_orthology)	EGLN1 SRC LRP2 PRKCA	1.51e-03	128	113	4	DOID:10763 (implicated_via_orthology)
Disease	intracerebral hemorrhage	TRIM5 DNAAF3	1.68e-03	16	113	2	EFO_0005669
Disease	Intellectual Disability	FRMPD4 PDGFRB ZMYM2 TMX2 LRP2 ALDH5A1 VPS53	1.70e-03	447	113	7	C3714756
Disease	Global developmental delay	FRMPD4 TMX2 VPS53 GABRA5	1.74e-03	133	113	4	C0557874
Disease	lateral occipital cortex volume measurement	BRINP1 PRKCA	1.90e-03	17	113	2	EFO_0010311
Disease	sphingosine 1-phosphate measurement	DNAAF3 EDARADD	2.14e-03	18	113	2	EFO_0800185
Disease	phosphatidylcholine 36:4 measurement	FADS3 FADS2	2.14e-03	18	113	2	EFO_0010382
Disease	level of Phosphatidylcholine (20:4_0:0) in blood serum	FADS3 FADS2	2.14e-03	18	113	2	OBA_2045110
Disease	level of Phosphatidylcholine (16:0_22:5) in blood serum	FADS3 FADS2	2.14e-03	18	113	2	OBA_2045079
Disease	schizophrenia, intelligence, self reported educational attainment	MYH11 ARHGAP15 LRP1B NUP205 SEMA6D PCNX1	2.20e-03	346	113	6	EFO_0004337, EFO_0004784, MONDO_0005090
Disease	diacylglycerol 38:5 measurement	FADS3 FADS2	2.38e-03	19	113	2	EFO_0020067
Disease	diacylglycerol 38:3 measurement	FADS3 FADS2	2.38e-03	19	113	2	EFO_0020065
Disease	Pheochromocytoma	EGLN1 RET	2.38e-03	19	113	2	C0031511
Disease	level of Phosphatidylcholine (16:0_18:2) in blood serum	FADS2 ATG4C	2.64e-03	20	113	2	OBA_2045071
Disease	Alzheimer disease	ANO4 ZSCAN12 CHST1 ABCA7 DNAAF3 SNX7 PCNX1	2.69e-03	485	113	7	MONDO_0004975
Disease	gait measurement	ARHGAP15 SNX7 UHRF1 ANO3	2.69e-03	150	113	4	EFO_0007680
Disease	level of Phosphatidylcholine (18:1_20:4) in blood serum	FADS3 FADS2	2.91e-03	21	113	2	OBA_2045104
Disease	level of Phosphatidylinositol (18:0_18:2) in blood serum	FADS3 FADS2	2.91e-03	21	113	2	OBA_2045156
Disease	level of Phosphatidylcholine (16:0_20:4) in blood serum	FADS3 FADS2	2.91e-03	21	113	2	OBA_2045076
Disease	PR interval	HSPG2 MYH11 SLC35F1 DNAAF3 FADS2 PRKCA GAREM1	3.01e-03	495	113	7	EFO_0004462
Disease	nucleus accumbens volume	KTN1 USH2A	3.19e-03	22	113	2	EFO_0006931
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	EGLN1 RET	3.49e-03	23	113	2	C1708353
Disease	phosphatidylserines measurement	FADS3 FADS2	3.49e-03	23	113	2	EFO_0020049
Disease	age at first sexual intercourse measurement	ARHGAP15 NUP205 DNAAF3 SEMA6D UHRF1 PLEKHA5	3.63e-03	383	113	6	EFO_0009749
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	ANO4 ARHGAP15 BRINP1 DNAAF3 SEMA6D SND1 PLEKHA5 ADGRL2 USH2A	3.72e-03	801	113	9	EFO_0003888, EFO_0007052, MONDO_0002491

Protein segments in the cluster

Peptide	Gene	Start	Entry
ILRLVDSAYKRRQEW	CARD10	731	Q9BWT7
ESTREEKERWIRSKY	AGAP11	421	Q8TF27
YERSFLREFHKWIER	ANAPC2	281	Q9UJX6
IYREFARWKVRNTAI	BRINP1	71	O60477
REMHVWREVFYRLER	ARC	111	Q7LC44
VKIFSSRDERSWFRE	ACVR1C	221	Q8NER5
LRFEATWETVYDKRA	ADGRL2	296	O95490
SREERESWIRAKYEQ	AGAP2	1026	Q99490
ERYKALVRWIDDESS	AMZ2	306	Q86W34
RLEYRQRWDEAFRKF	APEX1	181	P27695
FLEFWKRRRAVIAYD	ANO4	441	Q32M45
KRRRAVIAYDWDLID	ANO4	446	Q32M45
YSDDSKIWRPVEIFR	DIPK2B	101	Q9H7Y0
KRDTLWLALRETVYD	DISP2	1336	A7MBM2
VEEFRKDFISRIWLT	ATG4C	76	Q96DT6
KDFISRIWLTYREEF	ATG4C	81	Q96DT6
DVVTRTNKIRDRFWD	ABCA7	471	Q8IZY2
KRRRSILTYTWDLIE	ANO3	491	Q9BYT9
EIRLDAYKFVTQWRR	ANO3	786	Q9BYT9
RTGRYTLIEKWRDTE	RASSF8	36	Q8NHQ8
EILFKERAKLYRWDR	RANBP2	2931	P49792
RRSYEIMFREEFWRR	HSPG2	1456	P98160
RFRTRAYRRAAEKWE	NUP205	746	Q92621
LRTDRWLVIDRKVYN	FADS2	31	O95864
ESRSWFFERINKIDR	nan	361	O00370
FRWAERYRLAEPTEK	MDN1	1276	Q9NU22
EKRIVWTDARSDAIY	LRP1B	1436	Q9NZR2
FSWDDQKVRRVFVRK	FAIM2	91	Q9BWQ8
SEPRAREVVDWRKYE	MTIF2	436	P46199
ERRELKIQERTYSLW	MTMR7	446	Q9Y216
RVWAAIRDKYRSEAL	PRKCSH	271	P14314
VDYLEKRILWIDARS	LRP1	1441	Q07954
LYWCDARTDKIERID	LRP1	2066	Q07954
SEEEFKLWNRLYRLR	FANCM	681	Q8IYD8
REREVKLWDTRFFSS	CORO7	236	P57737
STYREIGRRLKFWNE	FCAR	66	P24071
RPVKFWERDYNTKRV	PCNX1	1516	Q96RV3
VFTATRYEDRRAEWV	PCSK7	436	Q16549
WRLKYERAVREVDFT	MYO18A	1371	Q92614
VSTRERYKWLRFSED	CES4A	101	Q5XG92
IDEYSRAVRDVKTDW	GAREM1	336	Q9H706
NEAKRRVRELYRAWY	NDUFA6	26	P56556
EFLRIKYWDRRRRAA	FAM47B	521	Q8NA70
RRTVERYDTEKDEWT	KBTBD2	396	Q8IY47
RWEEVQSYIRKRTAE	KTN1	496	Q86UP2
IDVFFRQSWKDERLR	GABRA5	96	P31644
ALDFDRVEKRLYWID	LRP2	3231	P98164
TDRDWRIFREDYSIT	DDX23	366	Q9BUQ8
SWIVKRSYEDFRVLD	ARHGAP32	166	A7KAX9
ERDEYKRRWEEEYTV	IFFO1	251	Q0D2I5
RDEAKLIAVEIYRWI	CKAP5	181	Q14008
YCWEKLRRAEVDLER	CXXC1	591	Q9P0U4
LRRAEVDLERVRVWY	CXXC1	596	Q9P0U4
VDLERVRVWYKLDEL	CXXC1	601	Q9P0U4
YALTVWRFFRDRTEE	ICMT	236	O60725
EAVMRWVYRAVDLRR	KLHL24	231	Q6TFL4
FRERDALEAVFRFWA	DNAAF3	161	Q8N9W5
ELWFAEFRDLRFVRT	DNAH3	356	Q8TD57
LERTAFRKDSQRWYV	FRMPD4	1081	Q14CM0
EAWKTYTERRNALRE	FNDC11	36	Q9BVV2
RAWRDYTRFQKLERE	CCDC191	361	Q8NCU4
KETRWKYHFEVVRDT	GCNT3	261	O95395
RTYESKEEARWRLSV	CTSF	196	Q9UBX1
ITVWYFDADERARAK	EGLN1	386	Q9GZT9
YHRADVEKVLRRWVD	EDARADD	186	Q8WWZ3
LRTRDETYIWEKITD	KLHDC1	101	Q8N7A1
WDTKDIYRQRSRALV	HYAL1	141	Q12794
RARYLAEKYEWDVAE	EEF2	631	P13639
DKWLVIERRVYDISR	FADS3	36	Q9Y5Q0
CYYIGKERRTWEERV	KLRC4	131	O43908
VEALAKATYERLFRW	MYH10	421	P35580
EWSRREAERLVKYRE	NDUFB11	116	Q9NX14
REVEEFLYRAVKRRW	MIER2	236	Q8N344
TSEERTRWAKAREYL	CROT	241	Q9UKG9
RYEIRWKVIESVSSD	PDGFRB	561	P09619
LVKEVAAWRERYEDS	NUMA1	806	Q14980
ERWSDALIKRREYLD	KIF13A	1096	Q9H1H9
IRYEVIRRCFEGKAW	USH2A	4186	O75445
IQAEEWYFGKITRRE	SRC	146	P12931
WYFGKITRRESERLL	SRC	151	P12931
YEAFCRWREVSAKER	ALDH5A1	106	P51649
IYSPEKREEAWRFIS	RHBDL2	111	Q9NX52
FFRRIDWEKLENREI	PRKCA	596	P17252
KTRVRFFRLDRWADV	MOV10	71	Q9HCE1
WVELKDDRIETYVRT	PIWIL2	641	Q8TC59
FFLRDITLRYKETRW	PTDSS2	431	Q9BVG9
WELLFYREVSEDRRQ	EPPK1	2991	P58107
VWELLFYREVSEDRR	EPPK1	3521	P58107
WELLFYREVSEDRRQ	EPPK1	4056	P58107
WIVLSSRRIEFYKES	ARHGAP15	106	Q53QZ3
TRERLYEWISIDKDE	INPPL1	881	O15357
RFAKERRLRIWRDYV	SND1	316	Q7KZF4
TESEKYRVVLRRWKS	MTRES1	216	Q9P0P8
SEFEVRRRYQDFLWL	SNX7	66	Q9UNH6
ALVVRFLTKRFIWEY	RERG	21	Q96A58
RILFLDDKRCEWIYR	SETDB1	376	Q15047
VKIFSSREERSWFRE	TGFBR1	231	P36897
ATYRSLVAREKVFWD	CLN8	51	Q9UBY8
TAEKWRFRLSYDIVA	CHST1	356	O43916
VEALAKATYERLFRW	MYH11	421	P35749
KATYERLFRWILTRV	MYH11	426	P35749
TWRNVAERTEKVYDR	PIGA	386	P37287
WEEYIIRTLSRVEFL	SLC35F1	236	Q5T1Q4
EVFRELTDVRRYWVD	TRIM5	286	Q9C035
ERDKRVTWIVEFFAN	TMX2	151	Q9Y320
KWAYERVEERFERIP	ZSWIM5	76	Q9P217
RDWLRVVASDKETYE	RPL22L1	91	Q6P5R6
RRYQDFDWLRSKLEE	SNX30	131	Q5VWJ9
FRVSWKDRDRDVIFL	UBE4B	166	O95155
DEIRSQYRADWKSRE	TOP1MT	291	Q969P6
RRYAWIKRQLVDYEE	VPS53	286	Q5VIR6
WERYTHRRKEVSEEN	TNKS2	1006	Q9H2K2
RWALDREQREKYELV	RET	226	P07949
SIFSRVEEDYLWRIK	ZMYM2	1191	Q9UBW7
GFWYDAEISRKRETR	UHRF1	236	Q96T88
RVWSLEESRYLQREK	nan	121	Q6AWC8
GWEKRVDSTDRVYFV	WWP1	461	Q9H0M0
ATAELERAWREYDKL	PLEKHA5	711	Q9HAU0
ERAWREYDKLEYDVT	PLEKHA5	716	Q9HAU0
IADEPWFTKTRVRYR	SEMA6D	406	Q8NFY4
EESWVVFRRYTDFSR	SNX16	136	P57768
IEEEKYTTRQDWDLR	ZSCAN12	21	O43309
ERRWDLDLTYVTERI	TNS2	126	Q63HR2
DDVDRTLDEWKRVTY	MAPK12	331	P53778
KWDYVERQLRDYDRI	LGI3	261	Q8N145
RWVTFLLKIYRAEDI	MYOF	356	Q9NZM1
ELAYEIFDKGRVRFW	MYOM2	1021	P54296