Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainRhoGAP

ARHGAP20 DEPDC1B

7.28e-0363382PF00620
DomainRHOGAP

ARHGAP20 DEPDC1B

7.51e-0364382PS50238
DomainRhoGAP_dom

ARHGAP20 DEPDC1B

7.51e-0364382IPR000198
Domain-

ARHGAP20 DEPDC1B

7.51e-03643821.10.555.10
DomainCH

ASPM SYNE2

7.73e-0365382SM00033
DomainCH

ASPM SYNE2

8.92e-0370382PF00307
DomainIQ

ASPM IQCF2

9.17e-0371382PF00612
Domain-

ASPM SYNE2

9.17e-03713821.10.418.10
DomainCH

ASPM SYNE2

9.67e-0373382PS50021
Domain-

RECQL RFX6 DEPDC1B

9.80e-032183831.10.10.10
DomainCH-domain

ASPM SYNE2

1.02e-0275382IPR001715
DomainIQ

ASPM IQCF2

1.18e-0281382SM00015
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RECQL PNPLA8 NOP58 EIF3B RPL38 NHP2 RNPS1 ZC3H15 VPS13C NOC3L

4.53e-061425411030948266
Pubmed

Functional proteomic analysis of human nucleolus.

RPF1 NOP58 NHP2 NOC3L

7.57e-0610641412429849
Pubmed

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

RPF1 NOP58 EIF3B RPL38 NHP2 RNPS1 NOC3L

2.13e-0573141729298432
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ASPM SLC39A6 PNPLA8 TMEM131 NOP58 DEPDC1B ZC3H15 SYNE2 NOC3L

4.73e-05148741933957083
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

TMEM131 ARID4A ZC3H15 VPS13C GCC2 SYNE2

5.11e-0556841637774976
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ERICH1 RECQL NOP58 NHP2 ARID4A RNPS1

7.44e-0560841636089195
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

RPF1 NOP58 EIF3B RNPS1 NOC3L

1.17e-0441041526949251
Pubmed

Cell-fate determination by ubiquitin-dependent regulation of translation.

NOP58 NHP2

1.22e-041441226399832
Pubmed

Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study.

CCDC60 OFCC1

1.22e-041441217903295
Pubmed

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.

RPF1 NOP58 RPL38 NHP2 RNPS1

1.47e-0443041538172120
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TMEM131 GCC2 SYNE2

1.50e-048741312465718
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ASPM RECQL NOP58 EIF3B RPL38 NHP2 RNPS1 NOC3L

1.56e-04135341829467282
Pubmed

Disruption of the lamin A and matrin-3 interaction by myopathic LMNA mutations.

NOP58 NHP2 RNPS1

2.01e-049641325948554
Pubmed

The deubiquitinase USP36 promotes snoRNP group SUMOylation and is essential for ribosome biogenesis.

NOP58 NHP2

2.81e-042141233852194
Pubmed

Comprehensive Proteomic Analysis of PGC7-Interacting Proteins.

NOP58 RPL38 ZC3H15 NOC3L

3.62e-0428741428712289
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

NOP58 EIF3B RPL38 NHP2 RNPS1 NOC3L

4.45e-0484741635850772
Pubmed

Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.

ASPM EIF3B GCC2

5.96e-0413941325476789
Pubmed

ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.

NOP58 NHP2 RNPS1 NOC3L

6.11e-0433041433301849
Pubmed

SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.

RECQL NOP58 RPL38

7.43e-0415041330154076
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

RPF1 NOP58 NHP2 NOC3L

7.53e-0434941425665578
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

RECQL NOP58 EIF3B RPL38 NHP2 RNPS1 NOC3L

8.03e-04131841730463901
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

TMEM131 RPL38 NHP2 RNPS1

8.54e-0436141430344098
Pubmed

Interactome Analysis of the Nucleocapsid Protein of SARS-CoV-2 Virus.

NOP58 NHP2 NOC3L

8.80e-0415941334578187
Pubmed

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

NOP58 EIF3B RPL38 RNPS1 ZC3H15

9.07e-0464141536057605
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

ASPM NOP58 EIF3B RPL38 ZC3H15 NOC3L

9.10e-0497141633306668
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RECQL NOP58 RPL38 SYNE2 NOC3L

9.85e-0465341522586326
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

RECQL NOP58 RPL38 NHP2 ZC3H15 SYNE2 NOC3L

9.94e-04136741732687490
Pubmed

Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.

CCDC112 EIF3B GEN1

1.05e-0316941331462741
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

RPF1 NOP58 RPL38 NHP2 NOC3L

1.16e-0367841530209976
GeneFamilyRNA binding motif containing

EIF3B RNPS1

2.73e-02213222725
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

CEP70 ASPM CCDC112 SLC39A6 RECQL VPS13C GCC2 SYNE2 TTLL7 NOC3L

5.01e-086564110M18979
CoexpressionDODD_NASOPHARYNGEAL_CARCINOMA_UP

ASPM ERICH1 SLC39A6 RECQL NOP58 EIF3B RNPS1 DEPDC1B ZC3H15 CXCL9 NOC3L

7.28e-0614074111M14427
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

CEP70 ASPM NOP58 ARID4A GEN1 GCC2 SYNE2

1.66e-06311407Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
ToppCellSepsis-Int-URO-Lymphocyte-B-Plasmablast|Int-URO / Disease, condition lineage and cell class

CEP70 ASPM TXLNB TTC21A EML6

9.84e-07196415e65b47d0ce1a5dd05f5f50e1639c8ec76fb42dc8
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CEP70 ASPM GEN1 DEPDC1B SYNE2

1.06e-06199415be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellLPS-antiTNF-Unknown|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ASPM C2orf92 GEN1 DEPDC1B

6.02e-06129414739b263296c28554967362060b154f7a95e1341d
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ASPM GEN1 DEPDC1B CXCL9

6.59e-0613241402491930097b75aaeedab9e8200711b0dc610944
ToppCell343B-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SERPINE2 TXLNB TTC21A ENTPD6

1.87e-05172414709c6b77a7a52b873eefb6caca28a41291d384af
ToppCell343B-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SERPINE2 TXLNB TTC21A ENTPD6

1.87e-05172414eb199c279fe8a2551121db37e9556893197d33ff
ToppCellURO-Lymphocyte-B-Plasmablast|URO / Disease, Lineage and Cell Type

CEP70 ASPM TEX14 ZCWPW2

1.87e-0517241448888ef50ac784b38aca81da68f8a94ce09c670d
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ASPM SERPINE2 DEPDC1B SYNE2

1.96e-05174414b43fb0fbb492c1be6e791a1c4d6c4e5956955ee4
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ASPM SERPINE2 DEPDC1B SYNE2

1.96e-0517441494575a605c725de83f66a6cf7df9d7bb360ffc56
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ASPM SERPINE2 DEPDC1B SYNE2

1.96e-0517441440c81ab36d7931e271e20d7d56fed32463c75f41
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPM SERPINE2 DEPDC1B SYNE2

1.96e-051744149d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPM SERPINE2 DEPDC1B SYNE2

1.96e-0517441453cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ASPM NOP58 EIF3B ENTPD6

2.05e-05176414dca70f309af24421f8dc708cbd88512814b8e79e
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ASPM NOP58 EIF3B ENTPD6

2.09e-051774149edfb50856f5e10672ab194ce0076d6a190e64de
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C SYNE2 TTLL7 CXCL9

2.14e-0517841401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellP15-Endothelial-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CEP70 ASPM GEN1 DEPDC1B

2.28e-051814140c5bc1660b8fc1e905ab4230202862de5be46ebd
ToppCell10x5'-bone_marrow-Mast-Mast_cell_lympho|bone_marrow / Manually curated celltypes from each tissue

ASPM TMEM131 ZCWPW2 TTLL7

2.28e-0518141456fa77ae31f3b7de6e441a439c33a11353b6573a
ToppCellP15-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CEP70 ASPM GEN1 DEPDC1B

2.28e-05181414f83565f09dd971c5cad2704a4a86bca0accd955e
ToppCell(02)_Cycling_Basal_(regeneration)-(1)_24hpi|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint

NOP58 EIF3B NHP2 RNPS1

2.71e-05189414311f3aed469be3c8ff913dcc5a2442daa8446d55
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CEP70 ASPM GEN1 DEPDC1B

2.82e-051914140ba5b112a82e489f5a21966f78a403a7436ce73b
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOP58 SERPINE2 ARHGAP20 VPS13C

2.82e-051914147d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOP58 SERPINE2 ARHGAP20 VPS13C

2.88e-0519241411088878043a6ff95ba1970361256a82e434b80a
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOP58 SERPINE2 ARHGAP20 VPS13C

3.06e-051954145c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NOP58 EIF3B VPS13C NOC3L

3.12e-05196414fd756b247b2d8a291e8e71bec6f1e463d6557536
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

ARID4A ZC3H15 GCC2 SYNE2

3.31e-0519941419674e1eaeb51e4196d847cb62aa437c852951d3
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NOP58 RPL38 GCC2 SYNE2

3.31e-051994143003badee037d4d63a8018a74c0aea213d049e43
ToppCellLPS_anti-TNF-Endothelial-Endothelial-FOXM1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ASPM GEN1 DEPDC1B SYNE2

3.31e-0519941498575fcce726589e93fbb4df1aab03e57cb56076
ToppCellSepsis-URO-Lymphocyte-B-Plasmablast|URO / Disease, condition lineage and cell class

CEP70 ASPM TEX14 ZCWPW2

3.31e-051994140df6cafb7f3b607cbe80b6f25b4fd62d421d01ee
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

ARID4A ZC3H15 GCC2 SYNE2

3.31e-05199414a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells-Neuroepithelial_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

ASPM GEN1 DEPDC1B SYNE2

3.37e-052004148f8b8c225cdc79baf16fe04be89bdb65e404a055
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CEP70 ASPM GEN1 DEPDC1B

3.37e-052004144cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells|10w / Sample Type, Dataset, Time_group, and Cell type.

ASPM GEN1 DEPDC1B SYNE2

3.37e-05200414a1f48eca9efb4f3ec3c9ace20f8c9257dd72c4ed
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

CEP70 ASPM GEN1 DEPDC1B

3.37e-052004149bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellSigmoid-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

ASPM TEX14 GEN1 DEPDC1B

3.37e-052004144e489ecf472857357d45e9f6c7a812aa48b72ebf
ToppCellLPS-antiTNF-Unknown-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ASPM GEN1 DEPDC1B

2.32e-04130413615c233c7c2600c1c2bc5cf5b1c501fc474564ef
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ASPM CCDC60 GEN1

2.53e-041344134d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPM CAPN9 GEN1

2.76e-04138413c1a46fbf1beffa12c3d1b78361e0613e2e9e2d13
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular|TCGA-Stomach / Sample_Type by Project: Shred V9

ASPM GEN1 ZC3H15

2.76e-0413841393497c0a5d5e54006653b2dedc7a7041e1a613e6
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A2|356C / Donor, Lineage, Cell class and subclass (all cells)

SERPINE2 TXLNB EML6

3.53e-041504136bdf9df586f348641a25a445e83a41e47e7f347e
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CEP70 ASPM CCDC60

3.88e-041554138e239470799426ea474a36f57e1b7e0d9365ca5f
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RFX6 TEX14 NOC3L

4.18e-041594137619d0d49738dd08daf01b42664691a5323aa793
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RFX6 TEX14 NOC3L

4.18e-041594134000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASPM DEPDC1B SLC26A6

4.42e-04162413ec29c6f1c31e41ddcb041a49c593910edaf0532c
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPF1 CCDC112 ENTPD6

4.50e-0416341313f76f2979558f5cd27fbfd1659b413b3cac18f5
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ASPM GEN1 DEPDC1B

4.50e-041634135285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASPM TXLNB DEPDC1B

4.58e-04164413ae09e5aabd1347b865474255e7411c04f63efb3b
ToppCellfacs-Marrow-KLS-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINE2 TTC21A CXCL9

4.83e-04167413d15168f46c1599d9fc68a05a7b822c4b439f2987
ToppCellfacs-Marrow-KLS-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINE2 TTC21A CXCL9

4.83e-041674132812353ff66e76f10bd327ceb0e6b009502a5258
ToppCellControl-NK|Control / Disease group and Cell class

SERPINE2 TTC21A EML6

4.91e-04168413683d389c8a1e791bfc773e63148115a21a6566db
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SERPINE2 SYNE2 EML6

5.00e-04169413d375a1df1ecc938f66bad92e54b8cda26ca9c472
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SERPINE2 SYNE2 EML6

5.00e-0416941358f805c0be507bd5fadc9ea3555032daabbc8ab8
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SERPINE2 SYNE2 EML6

5.00e-04169413e9c0e0f4c421c7bdbf1a7e33002f3cf22ea307cb
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ASPM GEN1 DEPDC1B

5.00e-04169413e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ASPM PADI4 DEPDC1B

5.08e-04170413cf22a843ae2d9cd6693507fed2b7c6a45abea10e
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ASPM POTEH DEPDC1B

5.17e-0417141313126a3fbee181412c13ffb0c347277b9d8f16f7
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ASPM NHP2 SYNE2

5.26e-04172413eee45759284baa3ed77da6a5fbcc4f8f6c553106
ToppCell5'-Adult-LargeIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ASPM SYNE2 EML6

5.35e-04173413b7e0193fd4983cb38d1bee441f608f73ee8743b9
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GEN1 SLC26A6 TTC21A

5.53e-0417541387e557f7508c88b2087db5d57e77d5e2c92ca083
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ASPM SERPINE2 DEPDC1B

5.53e-04175413553e68e8b439a2293efb969e1e2aa017ceb80daf
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ASPM SERPINE2 DEPDC1B

5.53e-0417541316d4e97271df1db9a0d167fc82a90d84d20dd1f2
ToppCellwk_20-22-Hematologic-Myeloid-Promonocyte-like|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ASPM PADI4 DEPDC1B

5.53e-04175413654299df246debe0a5b12f0d9568eb828bb94bb9
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ASPM SERPINE2 DEPDC1B

5.53e-04175413289d2aa7164bc02b1876b99f2fb67baa8e030c4e
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DEPDC1B TTLL7 EML6

5.53e-0417541389bf89466191da14896ed8928027f5b911436c22
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ASPM GEN1 DEPDC1B

5.53e-04175413876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

ASPM GEN1 DEPDC1B

5.53e-0417541374800a10f5ff25d5414fbccb0668f92ff077d1cc
ToppCellwk_20-22-Hematologic-Myeloid-Promyelocyte-like|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PADI4 EIF3B SLC26A6

5.62e-04176413ee33d7077a92c1fd371081e7c990c7266e711957
ToppCellControl-Lymphocyte-T_NK-CD8_TCM|Control / Disease, Lineage and Cell Type

RPL38 GCC2 SYNE2

5.62e-041764131a7948eb86ee1da607db4d0576312b2859d94523
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PNPLA8 TXLNB VPS13C

5.62e-04176413749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE2 TTLL7 CXCL9

5.72e-04177413ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE2 TTLL7 CXCL9

5.72e-04177413f471f7747d6e8db7546899019af9508f48a14f89
ToppCell(1)_Control_(PBS)-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|(1)_Control_(PBS) / Stress and Cell class

NOP58 SERPINE2 RPL38

5.72e-04177413d9e5ac5b8949a77e88e8094079167e4cf2c1bbd1
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE2 TTLL7 CXCL9

5.72e-04177413cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCellHealthy-Plasmablast|Healthy / disease group, cell group and cell class

ASPM DEPDC1B EML6

5.72e-041774134ff75c609ac9edf7a94bda42eb7124c559e8b6aa
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-plasmablast-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ASPM DEPDC1B EML6

5.72e-04177413d2c1f46913ac00bbc0bb9320d5652edc01b34179
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-plasmablast|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ASPM DEPDC1B EML6

5.72e-0417741365e090aad0ffb737ce034e25bd5b12a0b1dd9684
ToppCell368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CEP70 ASPM DEPDC1B

5.72e-04177413844017225e9039d1bc621a9630a30c2e9a51b36d
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-cDC1|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC112 ARHGAP20 CXCL9

5.72e-04177413345cebc19f93970a9a46be139208b300081f5493
ToppCell368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CEP70 ASPM DEPDC1B

5.72e-0417741326c25d10aa511b64cc7db43a8deea7b5d31bca96
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPM SERPINE2 SYNE2

5.81e-0417841315a99080e9f669572ab6d82934f324e6714846c1
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PADI4 NOP58 SYNE2

5.81e-0417841373936c2e7e8855b4ab65cad425686513dba331a3
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPM SERPINE2 SYNE2

5.81e-04178413200308e109abb7e6f8816a6f8cce6d56862d4098
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ASPM GEN1 EML6

5.91e-04179413021d782134126c6f7dce6b6ea50cc54bdaa39987
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ASPM GEN1 DEPDC1B

6.00e-04180413334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ASPM GEN1 DEPDC1B

6.00e-04180413f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCellCV-Healthy-2|CV / Virus stimulation, Condition and Cluster

ASPM RPL38 NHP2

6.00e-04180413e182e5c495dd82d4fcbf1a920086c70b064801f3
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ASPM TXLNB DEPDC1B

6.10e-041814136873c1138b28c130637d06b64981ad11c262e85f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ASPM GEN1 DEPDC1B

6.20e-04182413336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP70 TEX14 GEN1

6.20e-04182413fe46819c153a81911864473badc794f243705f98
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP70 TEX14 GEN1

6.20e-041824133948422707d6d5e021bcd7158e2eb69143613f62
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EIF3B SERPINE2 NHP2

6.30e-04183413523896bd1a93bdda81a009768baa3a1bdbd108b8
ToppCellControl-T/NK-proliferating_T/NK|Control / Disease group,lineage and cell class （2021.01.30）

ASPM SERPINE2 DEPDC1B

6.30e-04183413e740f05536d1e4b2512811771928eb65f6696409
ToppCellDividing_Macrophages-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

ASPM GEN1 DEPDC1B

6.40e-04184413f15ce786d25c6546804a6d1efcc2ad645f2ef54e
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

ASPM GEN1 DEPDC1B

6.50e-041854139766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ASPM GEN1 DEPDC1B

6.50e-0418541330e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell(101)_plasma|World / immune cells in Peripheral Blood (logTPM normalization)

ASPM DEPDC1B EML6

6.60e-0418641316267994c9ef1fb7118c4c665cbc96979ec2b703
ToppCelldroplet-Tongue-nan-24m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC39A6 SYNE2 TTLL7

6.60e-041864132913b5fd0617d024d600ba7015ec7b1961dade83
ToppCellfacs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPM GEN1 DEPDC1B

6.60e-041864139feef5936985e936b3d88f9d1bb012abb6468570
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPM RPL38 SYNE2

6.60e-041864134ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|lung / Disease (COVID-19 only), tissue and cell type

ASPM GEN1 EML6

6.60e-0418641366676d9395172de5707e204826a1c9f73b448cca
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPM RPL38 SYNE2

6.60e-0418641315ab6666748a641226e42e6ca6eeaf186a501c95
DrugClorgyline

CEP70 CCDC112 ARID4A VPS13C GCC2

1.25e-05168415ctd:D003010
DiseaseBreast Cancer, Familial

RECQL GEN1

7.61e-0430402C0346153
Diseasemean platelet volume

SERPINE2 NHP2 ARID4A GCC2 SYNE2 EML6

2.36e-031020406EFO_0004584
DiseaseMalignant neoplasm of breast

SLC39A6 RECQL SERPINE2 GEN1 SYNE2 CXCL9

3.05e-031074406C0006142
Diseasecutaneous melanoma, hair color

ARHGAP20 SYNE2

3.22e-0362402EFO_0000389, EFO_0003924
DiseaseFEV/FEC ratio

RFX6 ARHGAP20 VPS13C SYNE2 OFCC1 NOC3L

5.86e-031228406EFO_0004713

Protein segments in the cluster

PeptideGeneStartEntry
TISKNKKRKLKKKQQ

ERICH1

156

Q86X53
QIKQIKKDLKKYSKI

EIF3B

716

P55884
KKESIQIWKTKKQQK

CCDC112

221

Q8NEF3
RKNTPKQKEKKIKKQ

ARID4A

521

P29374
SNKEKKKKLKQFQKS

DEPDC1B

466

Q8WUY9
KIIQEKYRANKKKQK

ASPM

2581

Q8IZT6
ETAKKKKQQQLQKLK

CCDC60

76

Q8IWA6
QKKTITQIVKDKKKQ

RFX6

106

Q8HWS3
EGIKKKKQQKIKNIL

PADI4

516

Q9UM07
GKINKQLKKVLKKIV

NOP58

66

Q9Y2X3
ILKKINKAIVSKKNK

SERPINE2

91

P07093
FQQKALKQTKQKKSK

OFCC1

6

Q8IZS5
EKNFTKLAKKQKQLK

C2orf92

246

A0A1B0GVN3
QQVKKLEKALKKNVK

CEP70

301

Q8NHQ1
EKNTKIKQLLVKTKK

GCC2

1216

Q8IWJ2
YQKQKLEIKGKKQKR

GEN1

456

Q17RS7
KTLQKKKQQKIKEKL

IQCF2

26

Q8IXL9
IKKWEKQVSQKKKQK

CXCL9

86

Q07325
EKLQKNNITKKKKLV

EML6

1346

Q6ZMW3
LNAVLQKKKDIKFKK

CAPN9

546

O14815
KLYKCIKKAVKQKQI

NHP2

46

Q9NX24
KVKLENKLKNKQFKQ

NOC3L

21

Q8WTT2
KQKNIKQAIKSLKKY

PNPLA8

146

Q9NP80
KIKYNNNFKIKNKIK

ARHGAP20

116

Q9P2F6
VKKKSLLGVKENNKK

RNPS1

6

Q15287
VKQGNYVKVKKILKK

TEX14

31

Q8IWB6
QEKKAQLKIYKKFLK

SYNE2

2176

Q8WXH0
EKAQKLLQKVKKVFK

ENTPD6

191

O75354
KSVKIKKNKDNVKFK

RPL38

21

P63173
FLISQKKKLLKKQEQ

SLC26A6

571

Q9BXS9
LTLIKQFKDKKKKNQ

SLC39A6

441

Q13433
IQKKKVLTKKIKQCL

RECQL

36

P46063
KQQQRKEKLAAKKKL

RPF1

71

Q9H9Y2
QVKQKSKKLLNIKKE

TMEM131

1461

Q92545
KKKNIFTKNKVQLKI

VPS13C

2806

Q709C8
LKLKKVNKAEKVLKQ

TTC21A

806

Q8NDW8
KKLKLLQKKQVQIQK

TXLNB

181

Q8N3L3
VKKRKQTSKNNIEKK

ZCWPW2

216

Q504Y3
LKNKKGAKQQKFIKA

ZC3H15

31

Q8WU90
KQQVVKFLIKKKANL

POTEH

321

Q6S545
FQNYVKELKKKRKQK

TTLL7

141

Q6ZT98