Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	CCDC88C ARHGAP5 GRIPAP1 TRIO ARHGAP26 EIF2B5 TBC1D2 RASGEF1C HMGCR	1.91e-04	507	80	9	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	CCDC88C ARHGAP5 GRIPAP1 TRIO ARHGAP26 EIF2B5 TBC1D2 RASGEF1C HMGCR	1.91e-04	507	80	9	GO:0030695
GeneOntologyBiologicalProcess	intracellular transport	SCYL2 PIKFYVE DDX19B CCDC88C DDX19A GRIPAP1 SYNE3 PSAP MYO7A BLOC1S5 LSG1 TSC1 RILPL1 EEA1 LYST AGTPBP1 SMG6 XPO7	1.30e-05	1496	80	18	GO:0046907
GeneOntologyCellularComponent	centriole	FBF1 KIAA0586 SASS6 MPHOSPH9 RILPL1 WDR62	5.16e-05	172	80	6	GO:0005814
GeneOntologyCellularComponent	postsynaptic early endosome	GRIPAP1 EEA1	3.00e-04	7	80	2	GO:0098842
GeneOntologyCellularComponent	histone deacetylase complex	HDAC9 SIN3B HDAC4 TRRAP	3.18e-04	85	80	4	GO:0000118
GeneOntologyCellularComponent	nuclear protein-containing complex	DDX19B HDAC9 SIN3B PHC3 SYNE3 AFF2 HDAC4 POLA1 INTS13 SS18L1 POLR2D TRRAP SMG6 XPO7	6.77e-04	1377	80	14	GO:0140513
Domain	ARM-type_fold	SCYL2 CIP2A EIF2B5 USP24 ZYG11B TRRAP LYST AGTPBP1 ITPR2 XPO7	1.43e-06	339	78	10	IPR016024
Domain	CCDC74_C	CCDC74B CCDC74A	1.72e-05	2	78	2	PF14917
Domain	CCDC74	CCDC74B CCDC74A	1.72e-05	2	78	2	IPR033226
Domain	CCDC74_C	CCDC74B CCDC74A	1.72e-05	2	78	2	IPR029422
Domain	Hist_deacetylase_Gln_rich_N	HDAC9 HDAC4	5.15e-05	3	78	2	IPR024643
Domain	HDAC4_Gln	HDAC9 HDAC4	5.15e-05	3	78	2	PF12203
Domain	Histone_deAcase_II_euk	HDAC9 HDAC4	1.03e-04	4	78	2	IPR017320
Domain	PH_dom-like	PLEKHH1 TRIO MYO7A ARHGAP26 TBC1D2 PLCH1 LYST NOS1AP	3.99e-04	426	78	8	IPR011993
Domain	MYTH4	PLEKHH1 MYO7A	6.08e-04	9	78	2	PS51016
Domain	MyTH4_dom	PLEKHH1 MYO7A	6.08e-04	9	78	2	IPR000857
Domain	MyTH4	PLEKHH1 MYO7A	6.08e-04	9	78	2	PF00784
Domain	MyTH4	PLEKHH1 MYO7A	6.08e-04	9	78	2	SM00139
Domain	Hist_deacetyl	HDAC9 HDAC4	9.24e-04	11	78	2	PF00850
Domain	His_deacetylse_dom	HDAC9 HDAC4	9.24e-04	11	78	2	IPR023801
Domain	-	HDAC9 HDAC4	9.24e-04	11	78	2	3.40.800.20
Domain	His_deacetylse	HDAC9 HDAC4	9.24e-04	11	78	2	IPR000286
Domain	ARM-like	SCYL2 CIP2A ZYG11B TRRAP AGTPBP1 XPO7	9.29e-04	270	78	6	IPR011989
Domain	-	PLEKHH1 TRIO MYO7A ARHGAP26 TBC1D2 PLCH1 NOS1AP	1.23e-03	391	78	7	2.30.29.30
Domain	-	SCYL2 CIP2A ZYG11B TRRAP AGTPBP1	2.37e-03	222	78	5	1.25.10.10
Domain	G_patch	RBM6 SON	4.12e-03	23	78	2	SM00443
Domain	G_patch_dom	RBM6 SON	4.12e-03	23	78	2	IPR000467
Domain	Spectrin	SYNE3 TRIO	4.12e-03	23	78	2	PF00435
Domain	G_PATCH	RBM6 SON	4.12e-03	23	78	2	PS50174
Domain	G-patch	RBM6 SON	4.12e-03	23	78	2	PF01585
Domain	PH	PLEKHH1 TRIO ARHGAP26 TBC1D2 PLCH1	6.15e-03	278	78	5	SM00233
Domain	PH_DOMAIN	PLEKHH1 TRIO ARHGAP26 TBC1D2 PLCH1	6.24e-03	279	78	5	PS50003
Domain	PH_domain	PLEKHH1 TRIO ARHGAP26 TBC1D2 PLCH1	6.33e-03	280	78	5	IPR001849
Domain	ZnF_U1	ZFHX4 ZFHX3	6.50e-03	29	78	2	SM00451
Domain	Znf_U1	ZFHX4 ZFHX3	6.50e-03	29	78	2	IPR003604
Domain	FYVE	PIKFYVE EEA1	6.50e-03	29	78	2	PF01363
Domain	FYVE	PIKFYVE EEA1	6.50e-03	29	78	2	SM00064
Domain	Spectrin_repeat	SYNE3 TRIO	6.50e-03	29	78	2	IPR002017
Domain	Spectrin/alpha-actinin	SYNE3 TRIO	7.87e-03	32	78	2	IPR018159
Domain	SPEC	SYNE3 TRIO	7.87e-03	32	78	2	SM00150
Pathway	REACTOME_RHOJ_GTPASE_CYCLE	ARHGAP5 TRIO ARHGAP26	5.02e-05	16	65	3	MM15605
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DDX19B TET2 CCDC88C OPTN HDAC4 TRIO LSG1 PATZ1 CC2D1A MPHOSPH9 PLCH1 SHTN1 LYST ERBIN WDR62 NOS1AP	1.07e-10	861	80	16	36931259
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	PIKFYVE GRIPAP1 TRIO LSG1 CIP2A TSC1 HMGCR MPHOSPH9 PLCH1 ERBIN AGTPBP1 WDR62 KNL1 ITPR2	1.26e-09	733	80	14	34672954
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PLEKHH1 LRFN2 WDR7 TSC1 ZYG11B ERBIN AGTPBP1 NOS1AP SON XPO7	3.43e-08	407	80	10	12693553
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TET2 SIN3B PHC3 ZFHX4 CIP2A USP24 ZFHX3 SHTN1 WDR62 KNL1	4.40e-08	418	80	10	34709266
Pubmed	Mesenchymal dysplasia: a recessive mutation on chromosome 13 of the mouse.	BLOC1S5 LYST AGTPBP1	1.17e-07	5	80	3	8830098
Pubmed	Solo/Trio8, a membrane-associated short isoform of Trio, modulates endosome dynamics and neurite elongation.	TRIO EEA1 AGTPBP1	1.17e-07	5	80	3	16943433
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PIKFYVE HDAC9 CCDC88C UBE4A SIN3B GRIPAP1 CIP2A SS18L1 KIAA0586 PLCH1	2.03e-07	493	80	10	15368895
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SCYL2 PLEKHH1 TET2 HDAC9 ARHGAP5 UBE4A PSAP FBH1 MYO1E TRIO ZNF521 RILPL1 SHTN1 OLR1 AGTPBP1	2.10e-07	1285	80	15	35914814
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	SCYL2 SIN3B PHC3 ZFHX4 PATZ1 USP24 KNL1 SMG6	2.96e-07	282	80	8	23667531
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ARHGAP5 TRIO SSH3 CIP2A POLR2D TSC1 ZYG11B MPHOSPH9 ERBIN AGTPBP1 NOS1AP KNL1 ITPR2	7.71e-07	1049	80	13	27880917
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PLEKHH1 STK10 LRFN2 HDAC4 TRIO RASGEF1C RBM6 ZBTB8A ZFHX3 RILPL1 SHTN1 TRRAP ERBIN SMG6 XPO7	1.34e-06	1489	80	15	28611215
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PIKFYVE CCDC88C STK10 SYNE3 MYO1E TRIO MYO7A ARHGAP26 CC2D1A TRRAP LYST SMG6 ITPR2	1.37e-06	1105	80	13	35748872
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZFHX4 LSG1 INTS13 PATZ1 SS18L1 FBF1 ZFHX3 TRRAP AGTPBP1 WDR62 NOS1AP KNL1 SON	1.53e-06	1116	80	13	31753913
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	STK10 PHC3 EIF2B5 TBC1D2 USP24 RBM6 TRRAP ERBIN AGTPBP1 WDR62 SON	1.60e-06	774	80	11	15302935
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CCDC88C SIN3B HDAC4 TRIO WDR7 LSG1 PATZ1 TSC1 SHTN1 ERBIN FAM81A SMG6	2.03e-06	963	80	12	28671696
Pubmed	The histone deacetylase 9 gene encodes multiple protein isoforms.	HDAC9 SIN3B HDAC4	4.19e-06	14	80	3	12590135
Pubmed	Effect of 3-methyladenine on the fusion process of macropinosomes in EGF-stimulated A431 cells.	PIKFYVE EEA1	5.23e-06	2	80	2	17146146
Pubmed	The mouse ZFH-4 protein contains four homeodomains and twenty-two zinc fingers.	ZFHX4 ZFHX3	5.23e-06	2	80	2	10873665
Pubmed	A cDNA clone for a novel nuclear protein with DNA binding activity.	DDX19B SON	5.23e-06	2	80	2	1424986
Pubmed	DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε Degradation.	DDX19B DDX19A	5.23e-06	2	80	2	30699353
Pubmed	CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment.	CCDC74B CCDC74A	5.23e-06	2	80	2	31521166
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	TRIO LSG1 CIP2A KIAA0586 ERBIN WDR62	9.10e-06	209	80	6	36779422
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	SCYL2 SIN3B PHC3 LSG1 CC2D1A TSC1 SHTN1 ERBIN WDR62 KNL1 SON	9.56e-06	934	80	11	33916271
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	PSAP TRIO USP24 RBM6 TRRAP ITPR2	9.86e-06	212	80	6	33853758
Pubmed	The co-existence of transcriptional activator and transcriptional repressor MEF2 complexes influences tumor aggressiveness.	HDAC9 HDAC4	1.57e-05	3	80	2	28419090
Pubmed	HDAC1, HDAC4, and HDAC9 Bind to PC3/Tis21/Btg2 and Are Required for Its Inhibition of Cell Cycle Progression and Cyclin D1 Expression.	HDAC9 HDAC4	1.57e-05	3	80	2	27333946
Pubmed	RNA export factor Ddx19 is required for nuclear import of the SRF coactivator MKL1.	DDX19B DDX19A	1.57e-05	3	80	2	25585691
Pubmed	Dephosphorylation at a conserved SP motif governs cAMP sensitivity and nuclear localization of class IIa histone deacetylases.	HDAC9 HDAC4	1.57e-05	3	80	2	23297420
Pubmed	HDAC4 deacetylase associates with and represses the MEF2 transcription factor.	HDAC9 HDAC4	1.57e-05	3	80	2	10487761
Pubmed	Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1.	PIKFYVE EEA1	1.57e-05	3	80	2	16448788
Pubmed	Different class IIa HDACs repressive complexes regulate specific epigenetic responses related to cell survival in leiomyosarcoma cells.	HDAC9 HDAC4	1.57e-05	3	80	2	31754707
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	PLEKHH1 DDX19B MYO7A INTS13 ARHGAP26 SS18L1 FBF1 USP24 KNL1	1.62e-05	638	80	9	31182584
Pubmed	Interaction network of human early embryonic transcription factors.	TET2 PSAP HDAC4 ZFHX4 SS18L1 ZNF521 ZFHX3	1.70e-05	351	80	7	38297188
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	SCYL2 STK10 DDX19A BLOC1S5 CIP2A EIF2B5 CC2D1A MPHOSPH9 ERBIN AGTPBP1 NOS1AP	2.54e-05	1038	80	11	26673895
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	CCDC88C ARHGAP5 GRIPAP1 TRIO CIP2A SASS6 CC2D1A TSC1 MPHOSPH9 WDR62	2.61e-05	853	80	10	28718761
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	DDX19B DDX19A GRIPAP1 OPTN PSAP MYO1E POLA1 INTS13 TBC1D2 USP24 SHTN1 PAPSS1 XPO7	2.64e-05	1455	80	13	22863883
Pubmed	Behavioral abnormalities observed in Zfhx2-deficient mice.	ZFHX4 ZFHX3	3.13e-05	4	80	2	23300874
Pubmed	HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor.	HDAC9 HDAC4	3.13e-05	4	80	2	10523670
Pubmed	Deacetylation of Glutaminase by HDAC4 contributes to Lung Cancer Tumorigenesis.	HDAC9 HDAC4	3.13e-05	4	80	2	35864951
Pubmed	Chondrocyte mTORC1 activation stimulates miR-483-5p via HDAC4 in osteoarthritis progression.	HDAC4 TSC1	3.13e-05	4	80	2	30145794
Pubmed	Class IIa histone deacetylases: conducting development and differentiation.	HDAC9 HDAC4	3.13e-05	4	80	2	19412888
Pubmed	mHDA1/HDAC5 histone deacetylase interacts with and represses MEF2A transcriptional activity.	HDAC9 HDAC4	3.13e-05	4	80	2	10748098
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	HDAC9 PHC3 HDAC4 SS18L1 TRRAP	3.22e-05	157	80	5	30186101
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	TET2 HDAC4 MYO1E RBM6 ZFHX3 MPHOSPH9 ERBIN SMG6	3.31e-05	536	80	8	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	TET2 HDAC4 MYO1E RBM6 ZFHX3 MPHOSPH9 ERBIN SMG6	3.40e-05	538	80	8	10512203
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	SCYL2 PIKFYVE DDX19B UBE4A DDX19A LSG1 CIP2A SASS6 TSC1 WDR62 SON SMG6 ITPR2	3.52e-05	1496	80	13	32877691
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	SCYL2 LSG1 CIP2A USP24 CC2D1A MPHOSPH9 PLCH1 SHTN1 ERBIN	3.65e-05	708	80	9	39231216
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	SCYL2 GRIPAP1 HDAC4 MYO1E MYO7A PATZ1 CIP2A ARHGAP26 EIF2B5 ZYG11B EEA1 WDR62	4.75e-05	1321	80	12	27173435
Pubmed	Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays.	HDAC9 HMGCR ITPR2	5.03e-05	31	80	3	14684825
Pubmed	Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1.	HDAC9 HDAC4	5.20e-05	5	80	2	15194749
Pubmed	Tet1 and Tet2 maintain mesenchymal stem cell homeostasis via demethylation of the P2rX7 promoter.	TET2 LYST	5.20e-05	5	80	2	29858571
Pubmed	Distinct roles for CARMIL isoforms in cell migration.	MYO1E TRIO	5.20e-05	5	80	2	19846667
Pubmed	Myocyte enhancer factor 2 and class II histone deacetylases control a gender-specific pathway of cardioprotection mediated by the estrogen receptor.	HDAC9 HDAC4	5.20e-05	5	80	2	19893013
Pubmed	Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4.	HDAC9 HDAC4	5.20e-05	5	80	2	18332106
Pubmed	The functional interactome landscape of the human histone deacetylase family.	HDAC9 DDX19A SIN3B HDAC4 ZNF521 SON	5.61e-05	289	80	6	23752268
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	GRIPAP1 AFF2 WDR7 LSG1 CC2D1A ZFHX3 MPHOSPH9 ERBIN XPO7	7.46e-05	777	80	9	35844135
Pubmed	Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4.	HDAC9 HDAC4	7.79e-05	6	80	2	10825153
Pubmed	Muted, a new mutant affecting coat colour and otoliths of the mouse, and its position in linkage group XIV.	BLOC1S5 LYST	7.79e-05	6	80	2	5367369
Pubmed	Control of MEF2 transcriptional activity by coordinated phosphorylation and sumoylation.	HDAC9 HDAC4	7.79e-05	6	80	2	16356933
Pubmed	Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity.	HDAC9 ZNF521	7.79e-05	6	80	2	21173110
Pubmed	Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies.	HDAC9 ZFHX3	7.79e-05	6	80	2	23041239
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	HDAC9 ZNF432 SMG6 XPO7	8.94e-05	101	80	4	9872452
Pubmed	Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis.	SIN3B ZFHX3 TRRAP	9.33e-05	38	80	3	28218735
Pubmed	A global genomic transcriptional code associated with CNS-expressed genes.	ARHGAP5 ZFHX4 BLOC1S5 POLA1 CYP7B1 ZFHX3	9.49e-05	318	80	6	16919269
Pubmed	Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	USP24 PLCH1 AGTPBP1 SON	1.00e-04	104	80	4	10470851
Pubmed	The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.	TSC1 WDR62 NOS1AP XPO7	1.08e-04	106	80	4	31024071
Pubmed	Vestibular ganglion neurons survive hair cell defects in jerker, shaker, and Varitint-waddler mutants and downregulate calretinin expression.	MYO7A AGTPBP1	1.09e-04	7	80	2	17663432
Pubmed	The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase.	HDAC9 HDAC4	1.09e-04	7	80	2	12032081
Pubmed	Endosomal sorting by Semaphorin 4A in retinal pigment epithelium supports photoreceptor survival.	OPTN PSAP	1.09e-04	7	80	2	22465952
Pubmed	Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor.	HDAC9 HDAC4	1.09e-04	7	80	2	11022042
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	SCYL2 STK10 TRIO POLA1 SASS6 ERBIN KNL1	1.10e-04	472	80	7	38943005
Pubmed	Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.	SCYL2 STK10 GRIPAP1 SSH3 TSC1 ERBIN	1.34e-04	339	80	6	37232246
Pubmed	Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers.	HDAC9 HDAC4	1.45e-04	8	80	2	17786239
Pubmed	Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development.	SS18L1 KNL1	1.45e-04	8	80	2	35905187
Pubmed	N6 -methyladenosine-modified lncRNA ARHGAP5-AS1 stabilises CSDE1 and coordinates oncogenic RNA regulons in hepatocellular carcinoma.	ARHGAP5 METTL4	1.45e-04	8	80	2	36354136
Pubmed	Association of class II histone deacetylases with heterochromatin protein 1: potential role for histone methylation in control of muscle differentiation.	HDAC9 HDAC4	1.45e-04	8	80	2	12242305
Pubmed	Transcription repressor activity of spleen tyrosine kinase mediates breast tumor suppression.	HDAC9 HDAC4	1.45e-04	8	80	2	16288017
Pubmed	Normal lytic granule secretion by cytotoxic T lymphocytes deficient in BLOC-1, -2 and -3 and myosins Va, VIIa and XV.	MYO7A BLOC1S5	1.45e-04	8	80	2	15702992
Pubmed	BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.	SCYL2 PIKFYVE CIP2A SHTN1 ERBIN	1.45e-04	216	80	5	31519766
Pubmed	Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells.	TSC1 HMGCR	1.86e-04	9	80	2	33207246
Pubmed	Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo.	HDAC9 HDAC4	1.86e-04	9	80	2	11466315
Pubmed	Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development.	HDAC9 HDAC4	1.86e-04	9	80	2	15367668
Pubmed	Survival and lung pathology of mouse models of Hermansky-Pudlak syndrome and Chediak-Higashi syndrome.	BLOC1S5 LYST	1.86e-04	9	80	2	10193444
Pubmed	Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry.	ARHGAP5 ZNF432	1.86e-04	9	80	2	16777052
Pubmed	The DnaJ-related factor Mrj interacts with nuclear factor of activated T cells c3 and mediates transcriptional repression through class II histone deacetylase recruitment.	HDAC9 HDAC4	1.86e-04	9	80	2	16260608
Pubmed	Class II histone deacetylases: versatile regulators.	HDAC9 HDAC4	2.32e-04	10	80	2	12711221
Pubmed	Genome-wide association study of retinopathy in individuals without diabetes.	HDAC9 CYP7B1	2.32e-04	10	80	2	23393555
Pubmed	Histone Deacetylase 1 Is Essential for Rod Photoreceptor Differentiation by Regulating Acetylation at Histone H3 Lysine 9 and Histone H4 Lysine 12 in the Mouse Retina.	HDAC9 HDAC4	2.32e-04	10	80	2	28028172
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SCYL2 SIN3B USP24 CC2D1A SHTN1 TRRAP ERBIN	2.76e-04	549	80	7	38280479
Pubmed	MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration.	HDAC9 HDAC4	2.84e-04	11	80	2	31223056
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	SIN3B CIP2A SHTN1 OLR1 KNL1	3.19e-04	256	80	5	33397691
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	SCYL2 ARHGAP5 SSH3 CIP2A CC2D1A SHTN1 ERBIN	3.28e-04	565	80	7	25468996
Pubmed	Kinase signalling in excitatory neurons regulates sleep quantity and depth.	HDAC9 HDAC4	3.40e-04	12	80	2	36477539
Pubmed	MRG15 is a novel PALB2-interacting factor involved in homologous recombination.	SIN3B TRRAP	3.40e-04	12	80	2	19553677
Pubmed	A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.	GRIPAP1 RILPL1 XPO7	3.65e-04	60	80	3	19075228
Pubmed	Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.	MYO1E USP24 ZFHX3	3.83e-04	61	80	3	22916037
Pubmed	A genome-wide association study for reading and language abilities in two population cohorts.	ZFHX3 NOS1AP	4.01e-04	13	80	2	23738518
Pubmed	Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases.	HDAC9 HDAC4	4.01e-04	13	80	2	22693459
Pubmed	Analysis of BCL6-interacting proteins by tandem mass spectrometry.	PIKFYVE HDAC9 HDAC4	4.02e-04	62	80	3	16147992
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	PIKFYVE GRIPAP1 CIP2A RBM6 SASS6 TSC1 KNL1	4.17e-04	588	80	7	38580884
Interaction	CNTROB interactions	SCYL2 SYNE3 CIP2A SASS6 TSC1 MPHOSPH9 TRRAP LYST	2.84e-07	166	79	8	int:CNTROB
Interaction	KDM1A interactions	TET2 SIN3B PHC3 CCDC74B GRIPAP1 ZFHX4 CIP2A CCDC74A USP24 ZFHX3 TSC1 SHTN1 TRRAP WDR62 KNL1	3.20e-06	941	79	15	int:KDM1A
Interaction	RAB11A interactions	SCYL2 STK10 DDX19A GRIPAP1 OPTN HDAC4 TRIO WDR7 CIP2A CC2D1A TSC1 RILPL1 ERBIN ITPR2	3.74e-06	830	79	14	int:RAB11A
Interaction	YWHAH interactions	TET2 CCDC88C OPTN HDAC4 MYO1E TRIO LSG1 CC2D1A TSC1 MPHOSPH9 PLCH1 SHTN1 LYST ERBIN WDR62 NOS1AP	4.75e-06	1102	79	16	int:YWHAH
Interaction	C3orf18 interactions	UBE4A CIP2A EIF2B5 USP24 HMGCR XPO7	6.00e-06	115	79	6	int:C3orf18
Interaction	RAB9A interactions	SCYL2 PIKFYVE DDX19A GRIPAP1 OPTN WDR7 LSG1 CC2D1A TSC1 EEA1 ITPR2	1.98e-05	595	79	11	int:RAB9A
Interaction	YWHAG interactions	DDX19B TET2 CCDC88C OPTN HDAC4 USP24 TSC1 MPHOSPH9 PLCH1 SHTN1 TRRAP LYST ERBIN WDR62 NOS1AP SON	2.25e-05	1248	79	16	int:YWHAG
Interaction	CSPP1 interactions	SYNE3 CIP2A FBF1 SASS6 SMG6	3.77e-05	96	79	5	int:CSPP1
Interaction	PCM1 interactions	HDAC4 FBF1 KIAA0586 SASS6 CC2D1A TSC1 MPHOSPH9 EEA1 FAM81A	4.98e-05	434	79	9	int:PCM1
Interaction	EGR2 interactions	TET2 HDAC4 ZFHX4 SS18L1 ZNF521 ZFHX3	5.69e-05	171	79	6	int:EGR2
Interaction	PHF21A interactions	SIN3B GRIPAP1 ZFHX4 CIP2A USP24 ZFHX3 WDR62 KNL1	5.92e-05	343	79	8	int:PHF21A
Interaction	OFD1 interactions	SYNE3 CIP2A FBF1 SASS6 CC2D1A MPHOSPH9 TRRAP SMG6	6.42e-05	347	79	8	int:OFD1
Interaction	SFN interactions	TET2 HDAC9 CCDC88C HDAC4 MPHOSPH9 EEA1 PLCH1 SHTN1 LYST ERBIN WDR62	7.81e-05	692	79	11	int:SFN
Interaction	CPAP interactions	SYNE3 TRIO KIAA0586 SASS6 MPHOSPH9 LYST	8.04e-05	182	79	6	int:CPAP
Interaction	RAB5A interactions	SCYL2 PIKFYVE DDX19B CCDC88C GRIPAP1 WDR7 LSG1 CC2D1A TSC1 EEA1 ERBIN	9.33e-05	706	79	11	int:RAB5A
Interaction	NUP214 interactions	DDX19B HDAC9 DDX19A SYNE3 HDAC4 TRRAP	1.17e-04	195	79	6	int:NUP214
Interaction	GPR17 interactions	UBE4A CIP2A EIF2B5 USP24 HMGCR ITPR2 XPO7	1.22e-04	283	79	7	int:GPR17
Interaction	RCOR1 interactions	SIN3B GRIPAP1 ZFHX4 CIP2A USP24 ZFHX3 SHTN1 WDR62 KNL1	1.34e-04	494	79	9	int:RCOR1
Interaction	YWHAB interactions	TET2 CCDC88C OPTN HDAC4 TSC1 MPHOSPH9 PLCH1 SHTN1 TRRAP LYST ERBIN WDR62 SON	1.47e-04	1014	79	13	int:YWHAB
GeneFamily	Histone deacetylases, class IIA	HDAC9 HDAC4	5.23e-05	4	54	2	992
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZFHX4 ZFHX3	8.97e-04	15	54	2	529
GeneFamily	G-patch domain containing\|Minor histocompatibility antigens	RBM6 SON	1.95e-03	22	54	2	579
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	PIKFYVE EEA1	3.85e-03	31	54	2	81
GeneFamily	Nucleoporins	DDX19B DDX19A	4.10e-03	32	54	2	1051
GeneFamily	DEAD-box helicases	DDX19B DDX19A	6.98e-03	42	54	2	499
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	PLEKHH1 MYO7A	9.79e-03	50	54	2	1293
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP5 ARHGAP26	9.79e-03	50	54	2	721
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	PIKFYVE TET2 SIN3B PSAP HDAC4 ZFHX3 HMGCR SHTN1 SMG6	1.27e-05	467	80	9	M1347
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	PIKFYVE TET2 SIN3B PSAP HDAC4 ZFHX3 HMGCR SHTN1 SMG6	1.68e-05	484	80	9	MM999
Coexpression	GSE26559_TCF1_KO_VS_WT_LIN_NEG_CELL_DN	HDAC9 SIN3B EPYC KLK8 ZFHX3 OLR1	3.07e-05	196	80	6	M8422
Coexpression	GSE5503_PLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN	MYO1E WDR7 EIF2B5 KLK8 ZYG11B ITPR2	3.44e-05	200	80	6	M297
Coexpression	GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_UP	POLR2D TBC1D2 RBM6 PAPSS1 LYST ERBIN	3.44e-05	200	80	6	M3275
Coexpression	GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP	PLEKHH1 STK10 POLA1 PLCH1 METTL4 KNL1	3.44e-05	200	80	6	M7981
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	PIKFYVE STK10 HDAC4 TRIO WDR7 USP24 RBM6 ZFHX3 MPHOSPH9 TRRAP SON	5.67e-05	856	80	11	M4500
Coexpression	DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP	TET2 POLA1 CIP2A MPHOSPH9 WDR62 NOS1AP KNL1	5.95e-05	323	80	7	M2156
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2	ARHGAP5 UBE4A TRIO INTS13 CIP2A KIAA0586 USP24 ZFHX3 ZYG11B KNL1 ITPR2	6.55e-06	564	78	11	Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	PLEKHH1 ARHGAP5 UBE4A MYO1E TRIO INTS13 KIAA0586 USP24 ZYG11B PAPSS1 SON	1.08e-05	595	78	11	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1	SCYL2 PIKFYVE UBE4A DDX19A KIAA0586 TSC1 ZYG11B MPHOSPH9 EEA1 ERBIN AGTPBP1 SMG6	2.60e-05	780	78	12	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STK10 PSAP MYO7A CIP2A SHTN1 OLR1	5.33e-07	165	80	6	1dcd6b8aa192baeaa1f7bb334843edab6049b96f
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	UBE4A SYNE3 WDR7 HMGCR LYST AGTPBP1	1.25e-06	191	80	6	9454f642c3621370fa23640b631301346b300950
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	POLA1 CIP2A SASS6 MPHOSPH9 WDR62 KNL1	1.33e-06	193	80	6	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	Hematolymphoid-Microglia-TYROBP----L1-3\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HDAC9 ARHGAP26 RASGEF1C SHTN1 OLR1 ITPR2	1.64e-06	200	80	6	a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCell	Hematolymphoid-Microglia-TYROBP--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HDAC9 ARHGAP26 RASGEF1C SHTN1 OLR1 ITPR2	1.64e-06	200	80	6	dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCell	Hematolymphoid-Microglia-TYROBP-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HDAC9 ARHGAP26 RASGEF1C SHTN1 OLR1 ITPR2	1.64e-06	200	80	6	3bba5219453322198e8fdb0921d5f8c403598751
ToppCell	Hematolymphoid-Microglia\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HDAC9 ARHGAP26 RASGEF1C SHTN1 OLR1 ITPR2	1.64e-06	200	80	6	21bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCell	Hematolymphoid-Microglia-TYROBP---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HDAC9 ARHGAP26 RASGEF1C SHTN1 OLR1 ITPR2	1.64e-06	200	80	6	a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCell	Hematolymphoid-Microglia-TYROBP\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HDAC9 ARHGAP26 RASGEF1C SHTN1 OLR1 ITPR2	1.64e-06	200	80	6	33036d21c1c82109284473a515c4f890b33fdd5c
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PLEKHH1 MYO1E BLOC1S5 SHTN1 FAM81A	8.34e-06	153	80	5	91e9d70a5d3f6fd68c284ed0cc113f03d7d1e10b
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLEKHH1 MYO1E BLOC1S5 SHTN1 FAM81A	8.34e-06	153	80	5	f17f62646633cf95c810dcd5328978058741b276
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO7A CIP2A SHTN1 OLR1 KNL1	1.43e-05	171	80	5	845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STK10 PSAP MYO7A SHTN1 OLR1	1.64e-05	176	80	5	6548797336c9f4ca0f38e74a2c629e2a4defa252
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STK10 PSAP MYO7A SHTN1 OLR1	1.83e-05	180	80	5	cc31d2cd06161300b91b17a67bb432b75f0d719b
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STK10 PSAP MYO7A SHTN1 OLR1	1.93e-05	182	80	5	94d061b7b5ebbfc564c644bc8b2d52341927145d
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	ZFHX4 CYP7B1 ZYG11B EEA1 ITPR2	2.03e-05	184	80	5	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	PND03\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PSAP SHTN1 LYST OLR1 SON	2.20e-05	187	80	5	b3fcb36d853adfdea7172c5591de06f027e50af3
ToppCell	droplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	POLA1 CIP2A PLCH1 FAM81A KNL1	2.25e-05	188	80	5	0ec2a1b0505501ba18f10a5fce68c306a6292419
ToppCell	Control-Myeloid-Monocytes\|Control / group, cell type (main and fine annotations)	HDAC9 STK10 PSAP ARHGAP26 LYST	2.31e-05	189	80	5	3335d16bd0ffa0c1ddd06d7da645299148130c3f
ToppCell	facs-Skin-Anagen-3m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIP2A SASS6 MPHOSPH9 WDR62 KNL1	2.31e-05	189	80	5	bfa3ed1360991a3e32fad133017c413f8adc1eba
ToppCell	facs-Skin-Anagen-3m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIP2A SASS6 MPHOSPH9 WDR62 KNL1	2.31e-05	189	80	5	96f10c63656e446b4bb712f012e91ae986f8c2d0
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	POLA1 CIP2A MPHOSPH9 WDR62 KNL1	2.37e-05	190	80	5	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	Myeloid-Myeloid-B_(Activated_Macrophage)\|Myeloid / shred on cell class and cell subclass (v4)	PSAP EEA1 SHTN1 OLR1 ITPR2	2.43e-05	191	80	5	7bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCell	Immune-interstitial_macrophage_(C1Q_positive)\|World / Lineage, Cell type, age group and donor	HDAC9 PSAP MYO7A ARHGAP26 ITPR2	2.55e-05	193	80	5	64d598162a256ac6c9f8280c8a9133661dfbb10f
ToppCell	CF-Lymphoid-B_cell\|Lymphoid / Disease state, Lineage and Cell class	PIKFYVE HDAC9 MYO1E TRIO EEA1	2.55e-05	193	80	5	7ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TET2 PSAP ARHGAP26 TBC1D2 OLR1	2.68e-05	195	80	5	62dc745e1aa3e2e58afa16c7bb2cf9b03d4e8105
ToppCell	Children_(3_yrs)-Immune-monocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TET2 HDAC9 STK10 ARHGAP26 AGTPBP1	2.75e-05	196	80	5	cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCell	Children_(3_yrs)-Immune\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HDAC9 STK10 PSAP ARHGAP26 OLR1	2.82e-05	197	80	5	f18807124b91310fcd84238484a80ecdba684679
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TET2 STK10 PSAP ARHGAP26 TBC1D2	2.82e-05	197	80	5	1eb9ff8467118b943b5d443cb996168e1e1206b5
ToppCell	mild-cDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 HDAC9 ARHGAP5 MYO1E ZFHX3	3.03e-05	200	80	5	86f585bf9066b179bbcbc703bf43f15da4a07284
ToppCell	mild-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 PSAP ARHGAP26 ZFHX3 LYST	3.03e-05	200	80	5	934c2efc780318c66d667ca75be0de350361d351
ToppCell	Children_(3_yrs)-Immune-monocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TET2 HDAC9 STK10 ARHGAP26 AGTPBP1	3.03e-05	200	80	5	881ab995c90d75fd987d6e8f1f926a4bfcc4235f
ToppCell	severe-cDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HDAC9 ARHGAP5 MYO1E ZFHX3 FAM81A	3.03e-05	200	80	5	23e3d2fb86a71f62cca32640842fbba5dd163453
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_1\|E16.5-samps / Age Group, Lineage, Cell class and subclass	OPTN WDR7 PATZ1 FAM81A	5.70e-05	116	80	4	f32f7eddfe33adb3b5cf7c34667a481a305c5163
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_12\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HDAC9 MYO1E INTS13 FAM81A	6.10e-05	118	80	4	f0f40a0165156e3fc1584480b473b0e84e10d2cc
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_12\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HDAC9 MYO1E INTS13 FAM81A	6.30e-05	119	80	4	a6b359e7aafcc197f53eb5e19c3a905bc09497bb
ToppCell	metastatic_Lymph_Node-Endothelial_cells-Tumor_ECs\|Endothelial_cells / Location, Cell class and cell subclass	PHC3 KIAA0586 ZNF521 ERBIN	7.16e-05	123	80	4	de29861800d083e4977afbef59c1a81336824703
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZFHX4 EPYC RASGEF1C RILPL1	1.46e-04	148	80	4	d5cace5605bff2bb8248fadb51f2dad7539930ba
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb\|Cerebellum / BrainAtlas - Mouse McCarroll V32	AFF2 RASGEF1C PLCH1 NOS1AP	1.50e-04	149	80	4	6e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCell	10x5'-Lung-Myeloid_Monocytic-Cycling_mono\|Lung / Manually curated celltypes from each tissue	CIP2A SS18L1 KNL1 SMG6	1.79e-04	156	80	4	63b8cf14361b282872bc1c5b65d9fbc83e81a089
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLA1 SHTN1 KNL1 XPO7	1.79e-04	156	80	4	8349604bd801e20d33770f7d8243598c3756302b
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STK10 AFF2 SHTN1 OLR1	1.88e-04	158	80	4	6811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PSAP HDAC4 POLA1 OLR1	1.88e-04	158	80	4	f61ebe3a316e4259387cd9da83707f15e6473cae
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma\|TCGA-Bladder / Sample_Type by Project: Shred V9	PLEKHH1 PATZ1 SSH3 ZNF432	1.88e-04	158	80	4	dc559503bab3ec1b9ea54ef2e896d1be33e5344c
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STK10 AFF2 SHTN1 OLR1	2.07e-04	162	80	4	d712bc31840ad1523e3dbf884acbb428a8995001
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SASS6 MPHOSPH9 WDR62 KNL1	2.12e-04	163	80	4	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCYL2 KIAA0586 LYST ITPR2	2.17e-04	164	80	4	950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCYL2 KIAA0586 LYST ITPR2	2.17e-04	164	80	4	c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCell	droplet-Liver-nan-3m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCYL2 KIAA0586 LYST ITPR2	2.17e-04	164	80	4	bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_2\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CCDC74B CCDC74A ZNF432 RILPL1	2.22e-04	165	80	4	731147b4337fd0de4383dc8170b4f9ccd98caec6
ToppCell	Mild-Myeloid-Mast\|Mild / Condition, Lineage, Cell class and cell subclass	AFF2 RASGEF1C ZNF521 CYP7B1	2.22e-04	165	80	4	5fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCell	Mild-Myeloid-Mast-\|Mild / Condition, Lineage, Cell class and cell subclass	AFF2 RASGEF1C ZNF521 CYP7B1	2.22e-04	165	80	4	93d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCell	facs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A WDR7 ZNF521 NOS1AP	2.32e-04	167	80	4	961e722442d786ab15d1e490941d2be265a9057a
ToppCell	facs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A WDR7 ZNF521 NOS1AP	2.32e-04	167	80	4	3760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCell	PND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PSAP CIP2A SHTN1 KNL1	2.38e-04	168	80	4	4c402a1613fcf0a6e4d9b9d5551812940e91ff32
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	POLA1 CIP2A WDR62 KNL1	2.43e-04	169	80	4	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	AFF2 ZNF521 CYP7B1 PAPSS1	2.43e-04	169	80	4	f68195510b91e287fe1507455ca067ece77a3897
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HDAC9 MYO1E ZFHX3 SHTN1	2.49e-04	170	80	4	7bba77ae34a0259fad6ee98cf665ff50f77a1328
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HDAC9 MYO1E ZFHX3 SHTN1	2.49e-04	170	80	4	a43b977a7fe745536cf96b7c080397d9fa73086b
ToppCell	URO-Lymphocyte-B-Plasmablast\|URO / Disease, Lineage and Cell Type	CCDC74B MYO1E CIP2A KNL1	2.60e-04	172	80	4	48888ef50ac784b38aca81da68f8a94ce09c670d
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 ZFHX3 LYST XPO7	2.60e-04	172	80	4	d354424c1f861b6607dfd63b9724f4c237b30275
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PSAP MYO7A SHTN1 OLR1	2.66e-04	173	80	4	279efbab7810fa60ab12ea5d09a84800df4adef0
ToppCell	URO-Myeloid-cDC1\|URO / Disease, Lineage and Cell Type	HDAC9 ARHGAP5 CCDC74A SHTN1	2.66e-04	173	80	4	57f4e9f39ef6e02dca76f3dd0b39a0871917ed5a
ToppCell	10x5'-Lung-Myeloid_Dendritic-Cycling_Dendritic\|Lung / Manually curated celltypes from each tissue	PLEKHH1 POLA1 CIP2A CCDC74A	2.66e-04	173	80	4	62e0c18cfed9645e34a9d7029c94a8554f773714
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PSAP TRIO OLR1 ITPR2	2.72e-04	174	80	4	d5c22b43531414951666ee7542a66ed9380e2d14
ToppCell	ASK452-Immune-B_cell\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	SS18L1 ZNF521 FAM81A ITPR2	2.72e-04	174	80	4	69723f5666abc3af5f0431901a60246c9915ef81
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC74B CCDC74A WDR62 KNL1	2.72e-04	174	80	4	0227fea1678baa9168bd47c3b4aacb2592bb5867
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC74B CCDC74A WDR62 KNL1	2.72e-04	174	80	4	c2f8c59fca5f1ff6ffa6dc8cfce62da4b19fe9b3
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC74B CCDC74A WDR62 KNL1	2.72e-04	174	80	4	84024c04b0ce9f7068677d2d99ede56882b7dbd2
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TET2 STK10 SSH3 USP24	2.78e-04	175	80	4	c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCell	COVID-19_Severe-Classical_Monocyte-cMono_1\|Classical_Monocyte / Disease condition and Cell class	PSAP FBH1 SHTN1 ERBIN	2.78e-04	175	80	4	35ea2ed93538e6bf803029fcf7d9243f93e7733d
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CIP2A CYP7B1 ZFHX3 KNL1	2.78e-04	175	80	4	3e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCell	10x5'v1-week_14-16-Myeloid_DC-DC-DC1\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PLEKHH1 HDAC9 CCDC74A SHTN1	2.78e-04	175	80	4	398e2504021f587166ad04a2f0662bfcb4e1c0df
ToppCell	T_cells-Tph_and_Tfh\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	MYO1E MYO7A CYP7B1 LYST	2.84e-04	176	80	4	56c055488e34605d32562571a2fee621b47c9441
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T\|Lung / Manually curated celltypes from each tissue	POLA1 CIP2A WDR62 KNL1	2.84e-04	176	80	4	a40dfd8c4ba16757ff929b2f03a0628acf334de4
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP5 AFF2 LYST ERBIN	2.84e-04	176	80	4	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B-GC_B_(II)\|lymph-node_spleen / Manually curated celltypes from each tissue	AFF2 MYO1E FAM81A KNL1	2.84e-04	176	80	4	5788dd5b23ebb52f19d3b5bdbcfe25dee349cf77
ToppCell	3'_v3-blood-Mast-Mast_cell_granulo-myelo\|blood / Manually curated celltypes from each tissue	AFF2 TRIO CIP2A ZNF521	2.84e-04	176	80	4	d421b6b8e13894dbcf29548c0a6516c3dee8f9b1
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PSAP MYO7A SHTN1 OLR1	2.84e-04	176	80	4	b0b87eebcf5c994386b39ca607e17f10e9d9de74
ToppCell	facs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A CIP2A WDR62 KNL1	2.90e-04	177	80	4	8a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	SIN3B WDR7 HMGCR LYST	2.90e-04	177	80	4	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	facs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A CIP2A WDR62 KNL1	2.90e-04	177	80	4	e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO7A SHTN1 OLR1 KNL1	2.90e-04	177	80	4	67cc3a6461db5e0678f96b18224aeb83ad34b0f4
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PSAP MYO7A SHTN1 OLR1	2.90e-04	177	80	4	1e7b4c0e41649d57a2c219a3b7e693538b8b34e4
ToppCell	Severe-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PIKFYVE PSAP EEA1 NOS1AP	2.96e-04	178	80	4	b7374a97c51239782bed658381a02cb1b3d9bf66
ToppCell	metastatic_Brain-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	MYO7A SSH3 CCDC74A ZFHX3	2.96e-04	178	80	4	9a3581a0158dfa5a1cc942f8c532afb5e38b272a
ToppCell	10x5'-blood-Lymphocytic_NK-Cycling_NK\|blood / Manually curated celltypes from each tissue	POLA1 CIP2A WDR62 KNL1	3.03e-04	179	80	4	c93711273055a999335ba8d0f6500e4549f46cec
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLA1 CIP2A SASS6 KNL1	3.03e-04	179	80	4	54191c00b29f53b520cd3243b5791daa4a2c72d7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	POLA1 CIP2A WDR62 KNL1	3.03e-04	179	80	4	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	3'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PSAP ZFHX3 WDR62 ITPR2	3.03e-04	179	80	4	906555ce2ca264a0215b120c7ff7c9b411de6a34
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	TET2 HDAC9 ZFHX4 ZNF521	3.03e-04	179	80	4	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC88C HDAC4 MYO1E FAM81A	3.09e-04	180	80	4	023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIO SSH3 SS18L1 ITPR2	3.16e-04	181	80	4	4e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIO SSH3 SS18L1 ITPR2	3.16e-04	181	80	4	ad30c01290fb98adbd0caed301a584761212c977
ToppCell	COVID-19_Severe-Classical_Monocyte-cMono_1\|COVID-19_Severe / Disease condition and Cell class	PSAP FBH1 SHTN1 ERBIN	3.16e-04	181	80	4	0d07a67e8ee3bca687b378afbc4044434e63556d
ToppCell	droplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC9 CCDC88C ARHGAP5 ITPR2	3.16e-04	181	80	4	92d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCell	droplet-Lung-LUNG-30m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSAP MYO7A SHTN1 OLR1	3.16e-04	181	80	4	8fcdab61fad2efd324d2b27c58f5a594f1dc15de
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIO SSH3 SS18L1 ITPR2	3.16e-04	181	80	4	3a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OPTN AFF2 OLR1 KNL1	3.16e-04	181	80	4	566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OPTN AFF2 OLR1 KNL1	3.16e-04	181	80	4	db9528dc7cb0230e4c36cb27da69102c588c7ee9
Computational	Neighborhood of CDC16	DDX19B DDX19A USP24 MPHOSPH9 XPO7	2.40e-05	75	50	5	MORF_CDC16
Drug	Midecamycin [35457-80-8]; Down 200; 5uM; PC3; HT_HG-U133A	TRIO SSH3 ARHGAP26 CYP7B1 CC2D1A PLCH1 ITPR2	5.88e-06	196	80	7	6745_DN
Drug	vinblastine sulfate; Down 200; 0.1uM; MCF7; HT_HG-U133A	SCYL2 ARHGAP5 ARHGAP26 TBC1D2 USP24 PLCH1 ITPR2	6.28e-06	198	80	7	7517_DN
Drug	7-tricosene	TRRAP LYST	1.22e-05	2	80	2	CID006365493
Disease	Autosomal recessive primary microcephaly	SASS6 WDR62 KNL1	7.90e-06	15	78	3	cv:C3711387
Disease	Autosomal Recessive Primary Microcephaly	SASS6 WDR62 KNL1	2.64e-05	22	78	3	C3711387
Disease	intellectual disability (is_implicated_in)	CC2D1A TSC1 WDR62	6.85e-05	30	78	3	DOID:1059 (is_implicated_in)
Disease	colorectal cancer, particulate matter air pollution measurement	HDAC9 STK10	1.91e-04	8	78	2	EFO_0008255, MONDO_0005575
Disease	interventricular septum thickness	INTS13 ITPR2	3.06e-04	10	78	2	EFO_0009287
Disease	triacylglycerol 54:1 measurement	ZFHX4 ZNF432	3.06e-04	10	78	2	EFO_0010419
Disease	mean arterial pressure	HDAC9 GRIPAP1 HDAC4 WDR7 ZFHX3 MPHOSPH9 SMG6	3.56e-04	499	78	7	EFO_0006340
Disease	trimethylamine-N-oxide measurement	INTS13 ITPR2	6.15e-04	14	78	2	EFO_0010541
Disease	coronary artery disease, plasminogen activator inhibitor 1 measurement	HDAC9 ARHGAP26 SMG6	6.30e-04	63	78	3	EFO_0001645, EFO_0004792
Disease	platelet storage pool deficiency (implicated_via_orthology)	BLOC1S5 LYST	7.08e-04	15	78	2	DOID:2223 (implicated_via_orthology)
Disease	level of Phosphatidylethanolamine (16:0_20:4) in blood serum	MYO1E FAM81A	8.08e-04	16	78	2	OBA_2045137
Disease	primary autosomal recessive microcephaly (is_implicated_in)	WDR62 KNL1	8.08e-04	16	78	2	DOID:0070296 (is_implicated_in)
Disease	tissue plasminogen activator measurement, coronary artery disease	HDAC9 ARHGAP26 SMG6	8.92e-04	71	78	3	EFO_0001645, EFO_0004791
Disease	retinopathy	HDAC9 CYP7B1	9.14e-04	17	78	2	EFO_0003839
Disease	urate measurement, bone density	SCYL2 WDR7 TBC1D2 RBM6 COL6A5 ERBIN ITPR2	1.26e-03	619	78	7	EFO_0003923, EFO_0004531
Disease	Primary microcephaly	WDR62 KNL1	1.54e-03	22	78	2	C0431350
Disease	level of Phosphatidylethanolamine (16:0_18:2) in blood serum	MYO1E FAM81A	1.83e-03	24	78	2	OBA_2045136
Disease	beta-aminoisobutyric acid measurement	SYNE3 PAPSS1	1.83e-03	24	78	2	EFO_0010464
Disease	chronic obstructive pulmonary disease	TET2 HDAC9 HDAC4 RASGEF1C MPHOSPH9 METTL4 SMG6	2.29e-03	688	78	7	EFO_0000341
Disease	prostate carcinoma, breast carcinoma, ovarian carcinoma	TET2 CCDC88C	2.32e-03	27	78	2	EFO_0000305, EFO_0001075, EFO_0001663
Disease	myocardial infarction	HDAC9 HDAC4 ARHGAP26 HMGCR SMG6	2.37e-03	350	78	5	EFO_0000612
Disease	obesity (implicated_via_orthology)	ZFHX4 ZFHX3 TSC1 ITPR2	2.57e-03	215	78	4	DOID:9970 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
QHMRNLQQQELHRLL	SMG6	571	Q86US8
DTHKLDHINMNLNKL	ERBIN	756	Q96RT1
LENLKNMIHETNEHT	BLOC1S5	76	Q8TDH9
MKNLLTNHSNQNHLV	AFF2	81	P51816
QQQHSEMLAKLHEEI	CCDC74A	61	Q96AQ1
QQQHSEMLAKLHEEI	CCDC74B	61	Q96LY2
QMHLQKLESAHNPQQ	AGTPBP1	856	Q9UPW5
KMSHRDSNHQLQLLD	FAM81A	201	Q8TBF8
LAHQLARHNKLLQQM	ITPR2	2111	Q14571
HNKLAANSDHLMQIQ	INTS13	186	Q9NVM9
AQLHEHIKQQQEMLA	HDAC4	106	P56524
VTFQHQHQRLLENKM	LSG1	556	Q9H089
HMIHNRSKINLQDLQ	HMGCR	866	P04035
QHQTMDISLTKLDNH	CCDC88C	1306	Q9P219
LLVNEEILGNQIHMH	EIF2B5	276	Q13144
RALHLQNNNILEMHE	EPYC	261	Q99645
QVKQVEHENMLSLRH	MPHOSPH9	641	Q99550
QLLELGNKAHNDMHI	KNL1	1611	Q8NG31
LMTKQHNSRLEQSLH	RFPL4B	71	Q6ZWI9
KSKEQMELHHQNLNL	OLR1	116	P78380
MELHHQNLNLQETLK	OLR1	121	P78380
AQQQHLMLHTAALQQ	PHC3	71	Q8NDX5
KNHQNEIIAMAALVH	POLA1	551	P09884
RHSTEMLHNLNQQRK	PATZ1	21	Q9HBE1
NGHALLMQDTHKQLL	PAPSS1	426	O43252
EKQAMERLLSANHNH	PIKFYVE	601	Q9Y2I7
SHQLKLELNSMQEQL	EEA1	926	Q15075
KQEQHMHQEHLSLAQ	FBF1	1021	Q8TES7
MHQEHLSLAQQRLQL	FBF1	1026	Q8TES7
NMTLLDQLHTGLHQQ	IFNW1	101	P05000
LTHEQQLILNHKMEP	FBH1	441	Q8NFZ0
SIHQMKHHLQDSQQL	COL6A5	2366	A8TX70
KHSMNILNRIQEHFN	DDX19B	446	Q9UMR2
KLIRQQHEMCLNHSN	CC2D1A	581	Q6P1N0
DHHQQMFNIKQLLKA	LYST	1946	Q99698
DHNHDLMLLQLRDQA	KLK8	116	O60259
SQLQKNHDMNDELHL	CYP7B1	126	O75881
SHQALLQHLLLKEQM	HDAC9	391	Q9UKV0
HQLLLQNKDMLQHIS	NOS1AP	336	O75052
HSMNILNRIQEHFNK	DDX19A	446	Q9NUU7
QNMLEEQLTKNMHLH	GRIPAP1	796	Q4V328
KKDLEILHQQNIHQL	SASS6	236	Q6UVJ0
KHLPSLNEMEHQTLQ	METTL4	206	Q8N3J2
LTVLQMTHNKLLQEH	OPTN	386	Q96CV9
MTHNKLLQEHNNALK	OPTN	391	Q96CV9
IKHQQLSDLHKQNLE	RBM6	971	P78332
EVHMLLEHRKQQNES	POLR2D	36	O15514
LVQENPNHQHKMDQL	SYNE3	611	Q6ZMZ3
LLMNHLANVANNHKQ	ARHGAP26	506	Q9UNA1
MDKLVQNIARQLHHL	SIN3B	886	O75182
NETLHKEIHNLKQQL	SHTN1	296	A0MZ66
HKTKLEQLHIMQEQQ	SCYL2	606	Q6P3W7
HLNRVSQQHKINLMT	ARHGAP5	1391	Q13017
QEEQRQHLHLMVQLL	SSH3	91	Q8TE77
VKLQQEELNKHSHMI	CIP2A	871	Q8TCG1
IQKMLDENHHLIQCI	SS18L1	21	O75177
IHMQSDKHLNNVQNL	ZFHX4	716	Q86UP3
CQDVLSNKMHLQLHL	ZFHX4	1206	Q86UP3
LLKAMEHFPNHQQLQ	ZYG11B	411	Q9C0D3
MVTKLHSQIRQLQHD	TSC1	771	Q92574
MEISSHQSHLLQQLN	ZBTB8A	1	Q96BR9
QQQTRLMKINHDLRH	RILPL1	196	Q5EBL4
RMHQLLQALHQKLAA	RASGEF1C	151	Q8N431
TMETLLQNHQLRDHN	ZNF521	896	Q96K83
TQLSNKHELQLEQMH	STK10	581	O94804
LQKHLAELNHQKQLE	PSAP	141	P07602
KLEMENQHLKSHNQR	PLEKHH1	141	Q9ULM0
LLNIEEIHQLMHKLN	PLCH1	161	Q4KWH8
CMKQHLLEIDHRQQQ	WDR62	751	O43379
NLQIIIKELLSMHHQ	USP24	1651	Q9UPU5
DHLQDHLENQRMLKS	ZNF432	86	O94892
SQHGLLMQLLKLTHN	XPO7	211	Q9UIA9
HDQMVKINQNLHRLQ	UBE4A	526	Q14139
SLHALHLQNKENDML	TET2	1776	Q6N021
HLQNKENDMLSHTAN	TET2	1781	Q6N021
KNMAHHKLQTLATNL	WDR7	641	Q9Y4E6
NQLHMLTNRHDKFLD	TRRAP	2586	Q9Y4A5
INNHLIAKEMEHNTV	SON	1536	P18583
MEQHIRHLEKLQQQQ	KIAA0586	236	Q9BVV6
QQHVQLLMDKNHAKQ	TBC1D2	401	Q9BYX2
QRLQHHADKALTMNN	TRIO	826	O75962
LCQDMLNNKIHLQLH	ZFHX3	1256	Q15911
RMVNLHQLSLDHNLL	LRFN2	171	Q9ULH4
LLQKLQMQIGSHEHF	MYO1E	481	Q12965
DTTMLHKLNSQHKLN	MYO7A	521	Q13402