Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	neuregulin binding	ERBB3 ITGB4	1.80e-04	6	70	2	GO:0038132
GeneOntologyMolecularFunction	UDP-galactosyltransferase activity	B3GALT1 B3GNT4 WDFY3	1.90e-04	32	70	3	GO:0035250
GeneOntologyMolecularFunction	galactosyltransferase activity	B3GALT1 B3GNT4 WDFY3	2.49e-04	35	70	3	GO:0008378
GeneOntologyBiologicalProcess	regulation of secretion	ERBB3 SLC4A8 P2RX7 SEPTIN1 LRRC8A PLD2 DYSF F2RL2 CLCF1 LEPR PRL GAB2	1.69e-05	801	71	12	GO:0051046
GeneOntologyBiologicalProcess	positive regulation of secretion	SLC4A8 P2RX7 LRRC8A PLD2 F2RL2 CLCF1 LEPR PRL GAB2	1.78e-05	435	71	9	GO:0051047
GeneOntologyBiologicalProcess	secretion	ERBB3 SLC4A8 P2RX7 GNPTAB EXOC6B SEPTIN1 LRRC8A PLD2 DYSF F2RL2 CLCF1 LEPR PRL GAB2	6.05e-05	1221	71	14	GO:0046903
GeneOntologyBiologicalProcess	positive regulation of secretion by cell	SLC4A8 P2RX7 LRRC8A PLD2 F2RL2 CLCF1 LEPR GAB2	7.32e-05	404	71	8	GO:1903532
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	EXOC6B KDM2A WDFY3 SPEN ZBTB1	2.19e-06	102	71	5	10231032
Pubmed	Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication.	FASN PIK3C3	4.11e-06	2	71	2	34320401
Pubmed	Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes.	FASN LEPR	4.11e-06	2	71	2	21389266
Pubmed	Role of heparanase-driven inflammatory cascade in pathogenesis of diabetic nephropathy.	HPSE LEPR	4.11e-06	2	71	2	25008182
Pubmed	Asprosin-neutralizing antibodies as a treatment for metabolic syndrome.	NLRP12 P2RX7 LEPR	4.48e-06	16	71	3	33904407
Pubmed	The genetic basis of adrenal gland weight and structure in BXD recombinant inbred mice.	PITX2 LEPR	1.23e-05	3	71	2	21347846
Pubmed	Role of β4 integrin in HER-3-negative, K-RAS wild-type metastatic colorectal tumors receiving cetuximab.	ERBB3 ITGB4	1.23e-05	3	71	2	23617461
Pubmed	mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival.	PIK3C3 UVRAG	1.23e-05	3	71	2	26139536
Pubmed	Interaction of integrin alpha(6)beta(4) with ErbB3 and implication in heregulin-induced ErbB3/ErbB2-mediated DNA synthesis.	ERBB3 ITGB4	1.23e-05	3	71	2	20695903
Pubmed	Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease.	P2RX7 PITX2 F2RL2	1.82e-05	25	71	3	21518438
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZNF536 POGK PHF24 DISP2 RERE SPEN DCAF5	1.99e-05	407	71	7	12693553
Pubmed	Chronic activation of liver X receptor induces beta-cell apoptosis through hyperactivation of lipogenesis: liver X receptor-mediated lipotoxicity in pancreatic beta-cells.	FASN LEPR	2.46e-05	4	71	2	17369526
Pubmed	De novo lipogenesis maintains vascular homeostasis through endothelial nitric-oxide synthase (eNOS) palmitoylation.	FASN LEPR	2.46e-05	4	71	2	21098489
Pubmed	GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4.	GSTM3 FASN	2.46e-05	4	71	2	38228715
Pubmed	Class III PI-3-kinase activates phospholipase D in an amino acid-sensing mTORC1 pathway.	PIK3C3 PLD2	2.46e-05	4	71	2	22024166
Pubmed	Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG.	PIK3C3 UVRAG	2.46e-05	4	71	2	16799551
Pubmed	Identification of four new susceptibility loci for testicular germ cell tumour.	ZFPM1 GAB2	2.46e-05	4	71	2	26503584
Pubmed	Induction of ErbB-3 expression by alpha6beta4 integrin contributes to tamoxifen resistance in ERbeta1-negative breast carcinomas.	ERBB3 ITGB4	2.46e-05	4	71	2	18270579
Pubmed	Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy.	PIK3C3 UVRAG	4.09e-05	5	71	2	23878393
Pubmed	Argonaute2 mediates compensatory expansion of the pancreatic β cell.	AGO2 LEPR	4.09e-05	5	71	2	24361012
Pubmed	Rapid and Reversible Knockdown of Endogenously Tagged Endosomal Proteins via an Optimized HaloPROTAC Degrader.	PIK3C3 UVRAG	4.09e-05	5	71	2	30978004
Pubmed	NLRX1 Negatively Regulates Group A Streptococcus Invasion and Autophagy Induction by Interacting With the Beclin 1-UVRAG Complex.	PIK3C3 UVRAG	4.09e-05	5	71	2	30488027
Pubmed	Beclin1 antagonizes LAPTM4B-mediated EGFR overactivation in gastric cancer cells.	PIK3C3 UVRAG	4.09e-05	5	71	2	28479384
Pubmed	Architecture and dynamics of the autophagic phosphatidylinositol 3-kinase complex.	PIK3C3 UVRAG	4.09e-05	5	71	2	25490155
Pubmed	Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG.	PIK3C3 UVRAG	4.09e-05	5	71	2	18843052
Pubmed	Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.	PIK3C3 UVRAG	4.09e-05	5	71	2	25275521
Pubmed	A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic.	PIK3C3 UVRAG	4.09e-05	5	71	2	20643123
Pubmed	ORF3a-Mediated Incomplete Autophagy Facilitates Severe Acute Respiratory Syndrome Coronavirus-2 Replication.	PIK3C3 UVRAG	4.09e-05	5	71	2	34386498
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	P2RX7 DDX41 SPEN F2RL2 IL5RA LEPR	5.85e-05	329	71	6	17474147
Pubmed	Dapper1 promotes autophagy by enhancing the Beclin1-Vps34-Atg14L complex formation.	PIK3C3 UVRAG	6.13e-05	6	71	2	24980960
Pubmed	Regulation of Beclin 1 in autophagy.	PIK3C3 UVRAG	6.13e-05	6	71	2	19372752
Pubmed	NRBF2 regulates macroautophagy as a component of Vps34 Complex I.	PIK3C3 UVRAG	6.13e-05	6	71	2	24785657
Pubmed	DIRAS3 regulates the autophagosome initiation complex in dormant ovarian cancer cells.	PIK3C3 UVRAG	6.13e-05	6	71	2	24879154
Pubmed	The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression.	PIK3C3 UVRAG	6.13e-05	6	71	2	21062745
Pubmed	Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels.	PIK3C3 UVRAG	6.13e-05	6	71	2	25086043
Pubmed	The C-terminal region of ATG101 bridges ULK1 and PtdIns3K complex in autophagy initiation.	PIK3C3 UVRAG	6.13e-05	6	71	2	30081750
Pubmed	MicroRNA-103 represses hepatic de novo lipogenesis and alleviates NAFLD via targeting FASN and SCD1.	FASN LEPR	6.13e-05	6	71	2	32035613
Pubmed	ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction.	PIK3C3 UVRAG	6.13e-05	6	71	2	29313410
Pubmed	Interaction of Necl-4/CADM4 with ErbB3 and integrin α6 β4 and inhibition of ErbB2/ErbB3 signaling and hemidesmosome disassembly.	ERBB3 ITGB4	6.13e-05	6	71	2	23611113
Pubmed	NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity.	PIK3C3 UVRAG	6.13e-05	6	71	2	24849286
Pubmed	Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex.	PIK3C3 UVRAG	6.13e-05	6	71	2	8999962
Pubmed	PtdIns(4,5)P2 signaling regulates ATG14 and autophagy.	PIK3C3 UVRAG	6.13e-05	6	71	2	27621469
Pubmed	Direct binding of the EGF-like domain of neuregulin-1 to integrins ({alpha}v{beta}3 and {alpha}6{beta}4) is involved in neuregulin-1/ErbB signaling.	ERBB3 ITGB4	6.13e-05	6	71	2	20682778
Pubmed	A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis.	SLC4A8 ZFPM1 DCAF5	6.53e-05	38	71	3	38346162
Pubmed	Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase.	PIK3C3 UVRAG	8.57e-05	7	71	2	19050071
Pubmed	Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon.	PIK3C3 UVRAG	8.57e-05	7	71	2	25906440
Pubmed	Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.	PIK3C3 UVRAG	8.57e-05	7	71	2	19270693
Pubmed	Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.	PIK3C3 UVRAG	8.57e-05	7	71	2	19270696
Pubmed	PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex.	PIK3C3 UVRAG	8.57e-05	7	71	2	24056303
Pubmed	A fine-tuning mechanism underlying self-control for autophagy: deSUMOylation of BECN1 by SENP3.	PIK3C3 UVRAG	8.57e-05	7	71	2	31373534
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF536 AGO2 POGK ZNF362 WDFY3 RERE SKIL DDX41 TUBGCP5 DCAF5	8.69e-05	1116	71	10	31753913
Pubmed	Activation of RIG-I-Mediated Antiviral Signaling Triggers Autophagy Through the MAVS-TRAF6-Beclin-1 Signaling Axis.	PIK3C3 UVRAG	1.14e-04	8	71	2	30258449
Pubmed	CUL3 (cullin 3)-mediated ubiquitination and degradation of BECN1 (beclin 1) inhibit autophagy and promote tumor progression.	PIK3C3 UVRAG	1.14e-04	8	71	2	33977871
Pubmed	Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth.	PIK3C3 UVRAG	1.14e-04	8	71	2	27994061
Pubmed	EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance.	PIK3C3 UVRAG	1.47e-04	9	71	2	24034250
Pubmed	APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment.	APPL2 PIK3C3	1.47e-04	9	71	2	15016378
Pubmed	Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.	NLRP12 P2RX7	1.47e-04	9	71	2	24453977
Pubmed	Enpp2/Autotaxin in dermal papilla precursors is dispensable for hair follicle morphogenesis.	LIPH ITGB4	1.83e-04	10	71	2	23677168
Pubmed	Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex.	PIK3C3 UVRAG	1.83e-04	10	71	2	22493499
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF536 FASN FAM193A RERE NDUFA10 ZBTB1	2.15e-04	418	71	6	34709266
Pubmed	Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock.	NLRP12 P2RX7	2.23e-04	11	71	2	26572062
Pubmed	Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity.	NLRP12 LRRC8A	2.68e-04	12	71	2	32277911
Pubmed	RERE deficiency leads to decreased expression of GATA4 and the development of ventricular septal defects.	ERBB3 RERE	2.68e-04	12	71	2	30061196
Pubmed	Molecular markers of cardiac endocardial cushion development.	ERBB3 ZFPM1	3.16e-04	13	71	2	14648841
Pubmed	mTORC1 phosphorylates UVRAG to negatively regulate autophagosome and endosome maturation.	PIK3C3 UVRAG	3.16e-04	13	71	2	25533187
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	ZNF536 FASN PITX2 PUSL1 KDM2A SKIL SPEN NCAPH	3.56e-04	857	71	8	25609649
Pubmed	Axotomy-induced target disconnection promotes an additional death mechanism involved in motoneuron degeneration in amyotrophic lateral sclerosis transgenic mice.	NLRP12 P2RX7	3.68e-04	14	71	2	24424947
Pubmed	Allogeneic B cell immunomodulatory therapy in amyotrophic lateral sclerosis.	NLRP12 P2RX7	3.68e-04	14	71	2	38967302
Pubmed	Noradrenergic circuit control of non-REM sleep substates.	NLRP12 P2RX7	3.68e-04	14	71	2	34648731
Pubmed	Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-β-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning.	NLRP12 P2RX7	3.68e-04	14	71	2	35665767
Pubmed	Dissociation of the glucose and lipid regulatory functions of FoxO1 by targeted knockin of acetylation-defective alleles in mice.	FASN LEPR	3.68e-04	14	71	2	22055502
Pubmed	Early loss of cerebellar Purkinje cells in human and a transgenic mouse model of Alzheimer's disease.	NLRP12 P2RX7	3.68e-04	14	71	2	33688799
Pubmed	The activity of the aryl hydrocarbon receptor in T cells tunes the gut microenvironment to sustain autoimmunity and neuroinflammation.	NLRP12 P2RX7	3.68e-04	14	71	2	36787309
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FASN ADGRB2 DISP2 ZFPM1 WDFY3 DYSF SPEN ITGB4 UVRAG	4.06e-04	1105	71	9	35748872
Pubmed	δ-Catenin controls astrocyte morphogenesis via layer-specific astrocyte-neuron cadherin interactions.	NLRP12 P2RX7	4.24e-04	15	71	2	37707499
Pubmed	Inducing and measuring apoptotic cell death in mouse pancreatic β-cells and in isolated islets.	NLRP12 P2RX7	4.24e-04	15	71	2	35719268
Pubmed	AdipoRon accelerates bone repair of calvarial defect in diet-induced obesity mice.	NLRP12 P2RX7	4.24e-04	15	71	2	36873496
Pubmed	Behavioral and cortical arousal from sleep, muscimol-induced coma, and anesthesia by direct optogenetic stimulation of cortical neurons.	NLRP12 P2RX7	4.24e-04	15	71	2	38812551
Pubmed	Activation of neuronal Ras-related C3 botulinum toxin substrate 1 (Rac1) improves post-stroke recovery and axonal plasticity in mice.	NLRP12 P2RX7	4.24e-04	15	71	2	32964455
Pubmed	Intestinal transit-amplifying cells require METTL3 for growth factor signaling and cell survival.	NLRP12 P2RX7	4.24e-04	15	71	2	37883185
Pubmed	ERG K+ channels mediate a major component of action potential repolarization in lymphatic muscle.	NLRP12 P2RX7	4.24e-04	15	71	2	37689781
Pubmed	Tonic activity in lateral habenula neurons acts as a neutral valence brake on reward-seeking behavior.	NLRP12 P2RX7	4.84e-04	16	71	2	36049479
Pubmed	Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions.	B3GALT1 B3GNT4	4.84e-04	16	71	2	10580128
Pubmed	Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice.	WDFY3 UVRAG	4.84e-04	16	71	2	16096065
Pubmed	MIR205HG Is a Long Noncoding RNA that Regulates Growth Hormone and Prolactin Production in the Anterior Pituitary.	PITX2 PRL	4.84e-04	16	71	2	30982661
Pubmed	Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.	GSTM3 P2RX7 ITGB4 IL5RA	5.04e-04	179	71	4	19074885
Pubmed	Movement-related increases in subthalamic activity optimize locomotion.	NLRP12 P2RX7	5.48e-04	17	71	2	39068661
Pubmed	RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly.	PIK3C3 UVRAG	5.48e-04	17	71	2	21241894
Pubmed	A genetically targeted ion sensor reveals distinct seizure-related chloride and pH dynamics in GABAergic interneuron populations.	NLRP12 P2RX7	5.48e-04	17	71	2	37034992
Pubmed	Keap1-Nrf2 System Plays an Important Role in Invariant Natural Killer T Cell Development and Homeostasis.	NLRP12 P2RX7	5.48e-04	17	71	2	30995469
Pubmed	The bone microenvironment invigorates metastatic seeds for further dissemination.	NLRP12 P2RX7	5.48e-04	17	71	2	33878291
Pubmed	Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.	NLRP12 LEPR	5.48e-04	17	71	2	22297845
Pubmed	Ubiquitination of UVRAG by SMURF1 promotes autophagosome maturation and inhibits hepatocellular carcinoma growth.	PIK3C3 UVRAG	5.48e-04	17	71	2	30686098
Pubmed	Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism.	PIK3C3 UVRAG	6.16e-04	18	71	2	23954414
Pubmed	Generalized disruption of inherited genomic imprints leads to wide-ranging placental defects and dysregulated fetal growth.	LEPR PRL	6.16e-04	18	71	2	23085235
Pubmed	Vagal sensory neurons mediate the Bezold-Jarisch reflex and induce syncope.	NLRP12 P2RX7	6.16e-04	18	71	2	37914931
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	ZNF536 ZNF362 SPEN	6.66e-04	83	71	3	28794006
Pubmed	FOXL2 in the pituitary: molecular, genetic, and developmental analysis.	PITX2 PRL	6.87e-04	19	71	2	16840539
Pubmed	Abnormal Wnt and PI3Kinase signaling in the malformed intestine of lama5 deficient mice.	PITX2 ITGB4	6.87e-04	19	71	2	22666383
Pubmed	PITX genes are required for cell survival and Lhx3 activation.	PITX2 PRL	6.87e-04	19	71	2	15761027
Cytoband	12q24	B3GNT4 P2RX7	6.91e-04	25	71	2	12q24
Cytoband	1p35.1	TMEM39B ZNF362	1.14e-03	32	71	2	1p35.1
Cytoband	Ensembl 112 genes in cytogenetic band chr1p35	ADGRB2 TMEM39B ZNF362	1.28e-03	137	71	3	chr1p35
Cytoband	17q25	FASN ITGB4	1.68e-03	39	71	2	17q25
Coexpression	WHITESIDE_CISPLATIN_RESISTANCE_UP	ERBB3 FASN ITGB4	2.96e-06	11	70	3	M1499
Coexpression	LI_PBMC_MENACTRA_AGE_18_45YO_ANTI_POLYSACCHARIDE_ANTIBODY_CORRELATION_PROFILE_3DY_DN	ITGB4 PRL CFB	9.96e-06	16	70	3	M40964
Disease	asthma, body mass index	ERBB3 PIK3C3 RERE	4.00e-06	14	67	3	EFO_0004340, MONDO_0004979
Disease	basophil count	GEMIN8 ATAD2B ZFPM1 RERE CLCF1 IL5RA LEPR	1.12e-04	483	67	7	EFO_0005090
Disease	tumor necrosis factor ligand superfamily member 14 measurement	NLRP12 CFB	1.81e-04	9	67	2	EFO_0010613
Disease	C-X-C motif chemokine 5 measurement	NLRP12 ZFPM1	2.26e-04	10	67	2	EFO_0008058
Disease	basophil measurement	ZFPM1 RERE IL5RA	3.49e-04	60	67	3	EFO_0803539
Disease	quinate measurement	LEPR CFB	5.23e-04	15	67	2	EFO_0021167
Disease	Hypogonadotropic hypogonadism	LEPR PRL	5.23e-04	15	67	2	C0271623
Disease	Primary hypogonadism	LEPR PRL	5.23e-04	15	67	2	C0948896
Disease	Hypogonadism, Isolated Hypogonadotropic	LEPR PRL	5.23e-04	15	67	2	C3489396
Disease	Hypogonadism	LEPR PRL	5.97e-04	16	67	2	C0020619
Disease	Astrocytosis	ITGB4 LEPR	6.76e-04	17	67	2	C3887640
Disease	Gliosis	ITGB4 LEPR	6.76e-04	17	67	2	C0017639
Disease	Tourette syndrome, schizophrenia	ZNF536 RERE	7.59e-04	18	67	2	EFO_0004895, MONDO_0005090
Disease	eosinophil percentage of leukocytes	FAM193A ZFPM1 RERE NCAPH CLCF1 IL5RA LEPR	1.50e-03	746	67	7	EFO_0007991
Disease	neutrophil percentage of granulocytes	ZFPM1 RERE CLCF1 IL5RA	1.82e-03	228	67	4	EFO_0007994
Disease	Subfertility, Female	LEPR PRL	1.85e-03	28	67	2	C0341869
Disease	Sterility, Postpartum	LEPR PRL	1.85e-03	28	67	2	C0038279
Disease	Female sterility	LEPR PRL	1.85e-03	28	67	2	C0917730
Disease	Female infertility	LEPR PRL	1.85e-03	28	67	2	C0021361
Disease	eosinophil count	ERBB3 FAM193A ZNF362 ZFPM1 RERE DYSF NCAPH CLCF1 UVRAG IL5RA	1.86e-03	1488	67	10	EFO_0004842
Disease	eosinophil percentage of granulocytes	ZFPM1 RERE CLCF1 IL5RA	2.00e-03	234	67	4	EFO_0007996
Disease	brain connectivity measurement	ERBB3 EXOC6B LRRC8A RERE DYSF	2.17e-03	400	67	5	EFO_0005210
Disease	basophil count, eosinophil count	ZFPM1 RERE CLCF1 IL5RA	2.22e-03	241	67	4	EFO_0004842, EFO_0005090

Protein segments in the cluster

Peptide	Gene	Start	Entry
RCISHEYRYLYLSLR	ADGRB2	586	O60241
AGRIYISANRQLCYH	ERBB3	451	P21860
TLVERSTLDYLHYNR	CFAP61	1211	Q8NHU2
AYSLCRYRRVITVHQ	B3GALT1	291	Q9Y5Z6
DLTRYQFQSLRHCLT	ACSM5	331	Q6NUN0
EHLYALVGRSLRLYC	AMIGO3	286	Q86WK7
ALLRTCALYYHSGAL	DISP2	366	A7MBM2
CSEDTYSTLLQRYQR	FAM193A	106	P78312
ILTYQLCHTYVRCTR	AGO2	781	Q9UKV8
DRYVAICSPLHYSSR	OR5M10	121	Q6IEU7
IRITQSLCFIHRYYR	RFT1	441	Q96AA3
LFYCRKLRYLDLSHN	LRRC8A	681	Q8IWT6
YRLEDSVTYHCSRGL	CFB	181	P00751
YYSFVSHLRKIRTCT	GPR82	221	Q96P67
LQRQTYTCLSHRYGL	GNPTAB	6	Q3T906
YVNADHDLYCNTRRS	GEMIN8	171	Q9NWZ8
ERLYSLLSQCIYRHR	ATAD2B	1421	Q9ULI0
ASTYVQRAHLYSLRC	LOXL1	381	Q08397
RSERNLQAHLLYYCA	ZFPM1	251	Q8IX07
LQAHLLYYCASRQGT	ZFPM1	256	Q8IX07
RCLYTHEEYISLVLN	DCAF5	381	Q96JK2
TLQLRYHRSSLYCSD	LEPR	461	P48357
YRYLSTIHDRCLLRE	TUBGCP5	931	Q96RT8
FRTQLIRLCYSSDHE	GSTM3	111	P21266
CDHQRSVYLYLSSLR	LIPH	246	Q8WWY8
YRCLHIYSVLGARET	EXOC6B	296	Q9Y2D4
GQCLLLRRHSYLYAS	PGAP6	506	Q9HCN3
LRRHSYLYASCSCKA	PGAP6	511	Q9HCN3
TYQRSVLALRRAHDY	POGK	341	Q9P215
NFCRYLVHLADTIYR	PAXBP1	851	Q9Y5B6
ITKIYYCSRTHSQLA	DDX11	226	Q96FC9
RQTHGILEYYCRLLQ	DDX41	271	Q9UJV9
ERCHLDTTGTYTQYR	ITGB4	286	P16144
LRVYLHCTNTDNPRY	HPSE	431	Q9Y251
YSSRLLQYSDALEHL	NDUFA10	136	O95299
CYAAIIRTLNAYDHR	F2RL2	281	O00254
TNSRLRHCAYRCYAT	P2RX7	541	Q99572
DNYSRLRSYQVSLHC	IL5RA	141	Q01344
VLERYVYCITNRSHL	KDM2A	336	Q9Y2K7
FLTYRHCRNFSILLE	B3GNT4	96	Q9C0J1
TARCQSIYAYLNSHL	FGGY	356	Q96C11
QYHYLLDRNLSCRVV	SERPINA5	241	P05154
RRKQHLSSLQYYCAL	APPL2	171	Q8NEU8
SIHSLAAYYIDCIRQ	FASN	2281	P49327
TISCIFDYGNRYHLR	DYSF	1141	O75923
ALRAHSCLSDRLQYS	IL4I1	246	Q96RQ9
SRLSAYYNLLHCLRR	PRL	191	P01236
EYLYLHQCISRRAEN	GAB2	191	Q9UQC2
TSRTYLYRLATGCHR	PUSL1	126	Q8N0Z8
TLECYVHNLLRISVY	RRN3	221	Q9NYV6
CVRNSYDVFSLLRLH	UVRAG	186	Q9P2Y5
YIYCSRCTSDQLHIL	SKIL	191	P12757
DRYVAICSPLHYSSR	OR5M1	121	Q8NGP8
QCYTAFLHLRRYSNL	PIK3C3	801	Q8NEB9
EHLTCLRSQLFVAYR	SLC66A1L	21	A1A4F0
YVYRDTCNSSLASLR	PITX2	271	Q99697
HLDRGYNSCARTDLY	RERE	1136	Q9P2R6
SQLDHLSLYYCRCTL	SLC4A8	626	Q2Y0W8
CSLTLEDFLRYRHQA	PHF24	216	Q9UPV7
FLSTLHCQDYRSELL	NCAPH	261	Q15003
LRLTQNYEAYSHLLC	CLCF1	101	Q9UBD9
DYDRALQLLVNYHSC	TTPAL	91	Q9BTX7
THDLLYEGYRARCLQ	SEPTIN1	286	Q8WYJ6
ESATYSNRALCYLVL	TOMM34	226	Q15785
VYHCLNRTILYQFSR	WDFY3	2091	Q8IZQ1
SNVSDQYLTRHFCRY	SPEN	526	Q96T58
ILHRATLRDAAVYYC	TRAV26-2	91	A0A0B4J265
LTCTNRHLYQNTRSY	ZBTB1	236	Q9Y2K1
EAHANLYSRYLSCLQ	ZNF536	421	O15090
CYRAYSDSASLQIHL	ZNF362	346	Q5T0B9
VHTGLYTCLARNSYL	VSIG10L2	301	P0DP72
YTCLARNSYLDTRTQ	VSIG10L2	306	P0DP72
TYRTLCRGEYSILHR	PLD2	706	O14939
CRSLIHLFRTYSFLN	TMEM39B	176	Q9GZU3
RCRSAQVLHLYGATY	NLRP12	656	P59046