Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentanchoring junction

ATP7B ADGRB1 OBSCN TENM2 PTK2 HEG1 PTPRK KCND2 DSTYK PVR CGN CLTC DPP4 HSPG2 CAPN2 FRMPD2 EPB41L5 SORBS1 SPTBN4 SLC8A3 CDH22 XIRP2 DOCK7 LRP1 ANO7 POLDIP2

4.43e-0697620726GO:0070161
GeneOntologyCellularComponentsomatodendritic compartment

TRPM4 ABR KATNB1 ADGRB1 DPYSL5 TENM2 PTK2 HNRNPU ERMN SORT1 NELL2 PTPRK KCND2 SORCS2 CACNA1A CACNA1B HTR1D CAPN2 ARFGEF2 SPTBN4 SLC8A3 GNB5 LRP1 CNTNAP4 LRP6 WDFY3 SLC7A10

8.48e-05122820727GO:0036477
GeneOntologyCellularComponentmeprin A complex

MEP1A MEP1B

9.76e-0522072GO:0017090
GeneOntologyCellularComponentdendrite

ABR ADGRB1 DPYSL5 TENM2 PTK2 HNRNPU SORT1 NELL2 PTPRK KCND2 SORCS2 CACNA1A CACNA1B HTR1D CAPN2 ARFGEF2 SLC8A3 GNB5 LRP1 CNTNAP4 SLC7A10

1.30e-0485820721GO:0030425
GeneOntologyCellularComponentdendritic tree

ABR ADGRB1 DPYSL5 TENM2 PTK2 HNRNPU SORT1 NELL2 PTPRK KCND2 SORCS2 CACNA1A CACNA1B HTR1D CAPN2 ARFGEF2 SLC8A3 GNB5 LRP1 CNTNAP4 SLC7A10

1.34e-0486020721GO:0097447
GeneOntologyCellularComponentcell-cell junction

ATP7B ADGRB1 OBSCN TENM2 PTK2 HEG1 PTPRK PVR CGN DPP4 FRMPD2 EPB41L5 SORBS1 SPTBN4 CDH22 POLDIP2

2.81e-0459120716GO:0005911
DomainEGF-like_dom

GAS6 LAMC3 TENM2 MEP1A MEP1B NELL2 HEG1 HSPG2 ADAM29 TECTA LRP1 CNTNAP4 LRP6 TNXB

5.74e-0724920214IPR000742
DomainEGF

GAS6 MEP1A MEP1B HEG1 HSPG2 TECTA LRP1 CNTNAP4 LRP6 TNXB

1.14e-0612620210PF00008
DomainEGF

GAS6 LAMC3 TENM2 MEP1A MEP1B NELL2 HEG1 HSPG2 TECTA LRP1 CNTNAP4 LRP6 TNXB

1.76e-0623520213SM00181
DomainEGF_1

GAS6 LAMC3 TENM2 MEP1A MEP1B NELL2 HEG1 HSPG2 ADAM29 LRP1 CNTNAP4 LRP6 TNXB

4.33e-0625520213PS00022
DomainConA-like_dom

GAS6 ADGRV1 HNRNPU MEP1A MEP1B NELL2 PTPRK HERC1 HSPG2 COL9A1 CNTNAP4 WDFY3

4.89e-0621920212IPR013320
DomainEGF-like_CS

GAS6 LAMC3 TENM2 MEP1A MEP1B NELL2 HEG1 HSPG2 ADAM29 LRP1 CNTNAP4 LRP6 TNXB

5.58e-0626120213IPR013032
DomainEGF_2

GAS6 LAMC3 TENM2 MEP1A MEP1B NELL2 HEG1 HSPG2 ADAM29 LRP1 CNTNAP4 LRP6 TNXB

6.57e-0626520213PS01186
DomainEGF_3

GAS6 TENM2 MEP1A MEP1B NELL2 HEG1 HSPG2 ADAM29 LRP1 CNTNAP4 LRP6 TNXB

1.00e-0523520212PS50026
DomainATPase_dyneun-rel_AAA

MDN1 DNAH5 DYNC2H1 DNAH12

1.22e-05142024IPR011704
DomainAAA_5

MDN1 DNAH5 DYNC2H1 DNAH12

1.22e-05142024PF07728
Domain-

KATNB1 DMXL1 HIRA SORT1 SEMA6D HERC1 WDR24 DNAI3 TBC1D31 WDR6 TLE1 GNB5 WDFY3 MAPKBP1

1.67e-05333202142.130.10.10
DomainWD40/YVTN_repeat-like_dom

KATNB1 DMXL1 HIRA SORT1 SEMA6D HERC1 WDR24 DNAI3 TBC1D31 WDR6 TLE1 GNB5 WDFY3 MAPKBP1

1.79e-0533520214IPR015943
DomainWD40

KATNB1 DMXL1 HIRA HERC1 WDR24 DNAI3 TBC1D31 WDR6 TLE1 GNB5 WDFY3 MAPKBP1

2.64e-0525920212PF00400
DomainWD40

KATNB1 DMXL1 HIRA HERC1 WDR24 DNAI3 TBC1D31 WDR6 TLE1 GNB5 WDFY3 MAPKBP1

3.68e-0526820212SM00320
DomainWD40_repeat

KATNB1 DMXL1 HIRA HERC1 WDR24 DNAI3 TBC1D31 WDR6 TLE1 GNB5 WDFY3 MAPKBP1

4.26e-0527220212IPR001680
DomainWD_REPEATS_1

KATNB1 DMXL1 HIRA HERC1 WDR24 DNAI3 TBC1D31 WDR6 TLE1 GNB5 WDFY3 MAPKBP1

5.25e-0527820212PS00678
DomainWD_REPEATS_2

KATNB1 DMXL1 HIRA HERC1 WDR24 DNAI3 TBC1D31 WDR6 TLE1 GNB5 WDFY3 MAPKBP1

5.44e-0527920212PS50082
DomainWD_REPEATS_REGION

KATNB1 DMXL1 HIRA HERC1 WDR24 DNAI3 TBC1D31 WDR6 TLE1 GNB5 WDFY3 MAPKBP1

5.44e-0527920212PS50294
Domain-

GAS6 ADGRV1 NELL2 HSPG2 COL9A1 CNTNAP4 WDFY3

7.71e-059520272.60.120.200
DomainWD40_repeat_dom

KATNB1 DMXL1 HIRA HERC1 WDR24 DNAI3 TBC1D31 WDR6 TLE1 GNB5 WDFY3 MAPKBP1

9.87e-0529720212IPR017986
DomainClathrin_H-chain_propeller_rpt

CLTCL1 CLTC

1.16e-0422022IPR022365
DomainMeprin

MEP1A MEP1B

1.16e-0422022IPR008294
DomainClathrin-link

CLTCL1 CLTC

1.16e-0422022PF09268
Domain-

CLTCL1 CLTC

1.16e-04220222.130.10.110
DomainClathrin_heavy_chain

CLTCL1 CLTC

1.16e-0422022IPR016341
DomainClathrin_H-chain_propeller_N

CLTCL1 CLTC

1.16e-0422022IPR001473
DomainClathrin_H-chain_link/propller

CLTCL1 CLTC

1.16e-0422022IPR016025
DomainClathrin_propel

CLTCL1 CLTC

1.16e-0422022PF01394
DomainClathrin_H-chain_linker_core

CLTCL1 CLTC

1.16e-0422022IPR015348
DomainClathrin_H-chain_linker

CLTCL1 CLTC

3.47e-0432022IPR012331
DomainCLH

CLTCL1 CLTC

3.47e-0432022SM00299
DomainLaminin_G

GAS6 NELL2 HSPG2 COL9A1 CNTNAP4

4.05e-04582025IPR001791
DomainDynein_heavy_chain_D4_dom

DNAH5 DYNC2H1 DNAH12

4.16e-04142023IPR024317
DomainDynein_heavy_dom-2

DNAH5 DYNC2H1 DNAH12

4.16e-04142023IPR013602
DomainDHC_N2

DNAH5 DYNC2H1 DNAH12

4.16e-04142023PF08393
DomainAAA_8

DNAH5 DYNC2H1 DNAH12

4.16e-04142023PF12780
DomainWD40_repeat_CS

KATNB1 HIRA HERC1 WDR24 TBC1D31 TLE1 GNB5 WDFY3

4.22e-041642028IPR019775
DomainDHC_fam

DNAH5 DYNC2H1 DNAH12

5.15e-04152023IPR026983
DomainDynein_heavy

DNAH5 DYNC2H1 DNAH12

5.15e-04152023PF03028
DomainDynein_heavy_dom

DNAH5 DYNC2H1 DNAH12

5.15e-04152023IPR004273
DomainGalactose-bd-like

MYCBP2 LAMC3 MEP1B PTPRK HECTD3 CNTNAP4

5.49e-04942026IPR008979
DomainMAM_1

MEP1A MEP1B PTPRK

6.29e-04162023PS00740
Domain2-Hacid_dh_C

PHGDH CTBP2

6.88e-0442022PF02826
Domain2-Hacid_dh

PHGDH CTBP2

6.88e-0442022PF00389
DomainGPCR_chapero_1

ANKRD13B ANKRD13D

6.88e-0442022PF11904
DomainD_2_HYDROXYACID_DH_1

PHGDH CTBP2

6.88e-0442022PS00065
DomainD_2_HYDROXYACID_DH_2

PHGDH CTBP2

6.88e-0442022PS00670
DomainD_2_HYDROXYACID_DH_3

PHGDH CTBP2

6.88e-0442022PS00671
DomainD-isomer_2_OHA_DH_cat_dom

PHGDH CTBP2

6.88e-0442022IPR006139
DomainANKRD13

ANKRD13B ANKRD13D

6.88e-0442022IPR021832
DomainD-isomer_DH_CS

PHGDH CTBP2

6.88e-0442022IPR029753
DomainMAM

MEP1A MEP1B PTPRK

7.58e-04172023SM00137
DomainPH_dom-like

ABR OBSCN PTK2 ELMO1 ARHGEF9 TECPR1 FRMPD2 EPB41L5 SPTBN4 PLCH2 MYLIP WDFY3 PHLPP2

7.75e-0442620213IPR011993
DomainLaminin_G_2

GAS6 NELL2 HSPG2 CNTNAP4

8.95e-04402024PF02210
DomainMAM

MEP1A MEP1B PTPRK

9.02e-04182023PF00629
DomainMAM_dom

MEP1A MEP1B PTPRK

9.02e-04182023IPR000998
DomainMAM_2

MEP1A MEP1B PTPRK

9.02e-04182023PS50060
DomainVWC_out

NELL2 MUC5B TECTA

1.06e-03192023SM00215
DomainSortilin_C

SORT1 SORCS2

1.14e-0352022PF15901
DomainSortilin-Vps10

SORT1 SORCS2

1.14e-0352022PF15902
DomainVPS10

SORT1 SORCS2

1.14e-0352022IPR006581
DomainSortilin_N

SORT1 SORCS2

1.14e-0352022IPR031778
DomainSortilin_C

SORT1 SORCS2

1.14e-0352022IPR031777
DomainVPS10

SORT1 SORCS2

1.14e-0352022SM00602
DomainD-isomer_DH_NAD-bd

PHGDH CTBP2

1.14e-0352022IPR006140
DomainLamG

GAS6 NELL2 HSPG2 CNTNAP4

1.29e-03442024SM00282
DomainFERM_M

PTK2 FRMPD2 EPB41L5 MYLIP

1.52e-03462024PF00373
Domain6-blade_b-propeller_TolB-like

TENM2 WDR6 LRP1 LRP6

1.52e-03462024IPR011042
Domain-

MYCBP2 HERC1 TECPR1

1.65e-032220232.130.10.30
DomainDUF3398

DOCK6 DOCK7

1.70e-0362022PF11878
DomainPeptidase_M12A

MEP1A MEP1B

1.70e-0362022IPR001506
DomainAstacin

MEP1A MEP1B

1.70e-0362022PF01400
DomainDOCK_C/D_N

DOCK6 DOCK7

1.70e-0362022IPR021816
DomainPH_12

ELMO1 PLCH2

1.70e-0362022PF16457
DomainRCC1/BLIP-II

MYCBP2 HERC1 TECPR1

1.88e-03232023IPR009091
DomainFERM_central

PTK2 FRMPD2 EPB41L5 MYLIP

1.92e-03492024IPR019748
DomainFERM_domain

PTK2 FRMPD2 EPB41L5 MYLIP

1.92e-03492024IPR000299
DomainFERM/acyl-CoA-bd_prot_3-hlx

PTK2 FRMPD2 EPB41L5 MYLIP

2.07e-03502024IPR014352
DomainFERM_1

PTK2 FRMPD2 EPB41L5 MYLIP

2.07e-03502024PS00660
DomainFERM_2

PTK2 FRMPD2 EPB41L5 MYLIP

2.07e-03502024PS00661
DomainFERM_3

PTK2 FRMPD2 EPB41L5 MYLIP

2.07e-03502024PS50057
DomainBand_41_domain

PTK2 FRMPD2 EPB41L5 MYLIP

2.07e-03502024IPR019749
DomainB41

PTK2 FRMPD2 EPB41L5 MYLIP

2.07e-03502024SM00295
DomainEGF_CA

GAS6 TENM2 NELL2 HEG1 HSPG2 LRP1

2.13e-031222026SM00179
DomainTRAF-like

FBXO40 MEP1A MEP1B

2.13e-03242023IPR008974
DomainEGF-like_Ca-bd_dom

GAS6 TENM2 NELL2 HEG1 HSPG2 LRP1

2.31e-031242026IPR001881
DomainClathrin

CLTCL1 CLTC

2.36e-0372022PF00637
DomainAPC_su10/DOC_dom

MYCBP2 HECTD3

2.36e-0372022IPR004939
DomainDOC

MYCBP2 HECTD3

2.36e-0372022PS51284
DomainCa_chan_IQ

CACNA1A CACNA1B

2.36e-0372022SM01062
DomainCa_chan_IQ

CACNA1A CACNA1B

2.36e-0372022PF08763
DomainANAPC10

MYCBP2 HECTD3

2.36e-0372022PF03256
DomainVDCC_a1su_IQ

CACNA1A CACNA1B

2.36e-0372022IPR014873
DomainGPHH

CACNA1A CACNA1B

2.36e-0372022PF16905
DomainGPHH_dom

CACNA1A CACNA1B

2.36e-0372022IPR031649
DomainCHCR

CLTCL1 CLTC

2.36e-0372022PS50236
DomainAPC10

MYCBP2 HECTD3

2.36e-0372022SM01337
DomainFERM_C

FRMPD2 EPB41L5 MYLIP

2.70e-03262023PF09380
DomainHECT

HERC1 HECTD3 UBE3B

3.01e-03272023PF00632
DomainHECTc

HERC1 HECTD3 UBE3B

3.01e-03272023SM00119
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TRPM4 CLTCL1 ABR GTPBP6 MYCBP2 PIEZO1 INTS1 OBSCN LAMC3 ELAC2 HIRA TPCN1 TINAGL1 HEG1 MDN1 WIZ MAP3K11 HERC1 SIPA1L2 BRAT1 DOCK6 WDR24 ANKRD13D HSPG2 EP400 UBE3B AOC2 POLRMT ARFGEF2 HEYL NUP188 WDFY3 MAPKBP1

2.80e-1411052083335748872
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

PIGN DCAKD MYCBP2 SUSD6 RPN1 ERAP1 PIEZO1 LAMC3 GALNT7 ELAC2 DMXL1 TPCN1 SORT1 NELL2 HEG1 PTPRK PVR HSPG2 LEMD2 ARFGEF2 ALG11 CACHD1 SELENON LRP1 LRP6

6.87e-0812012082535696571
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DCAKD KBTBD3 TRPM4 CPAMD8 ABR GTPBP6 MYCBP2 GAS6 DPYSL5 OBSCN TMEM63B ADGRV1 GALNT7 PTK2 HNRNPU KIDINS220 PVR ARHGEF9 KATNIP DOCK6 FRMPD2 GPATCH2 TECTA SELENON INTS8 SPTBN4 LRP1 CTBP2

8.78e-0814892082828611215
Pubmed

Defining the membrane proteome of NK cells.

PIGN DCAKD CLTCL1 ATP7B ABR MYCBP2 RPN1 ERAP1 KATNB1 INTS1 GALNT7 ELMO1 HNRNPU KIDINS220 MDN1 CLTC MAP3K11 BRAT1 DPP4 LEMD2 ARFGEF2 ALG11 ORC2 NUP188

1.62e-0711682082419946888
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

RBM10 CSMD3 TENM2 KIDINS220 SEMA6D XPO5 CLTC ARHGEF9 KATNIP SIPA1L2 EP400 SORBS1 DOCK7 MAPKBP1

1.93e-074072081412693553
Pubmed

Pathogenic variants of DYNC2H1, KIAA0556, and PTPN11 associated with hypothalamic hamartoma.

PTPN11 KATNIP DYNC2H1

2.11e-073208331197031
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SETX MYCBP2 RPN1 RBM10 INTS1 DPYSL5 DBT PHGDH HNRNPU HIRA KIDINS220 WIZ CLTC SIPA1L2 DOCK6 HSPA6 EP400 CHD7 INTS8 DOCK7 POLDIP2 TNXB

6.57e-0710822082238697112
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

DCAKD RPN1 GALNT7 PHGDH SORT1 KIDINS220 PTPRK XPO5 PVR CLTC BRAT1 HSPA6 HECTD3 DYNC2H1 CAPN2 LEMD2 CACHD1 INTS8 LRP6 NUP188

1.13e-069422082031073040
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

HDAC9 ZSWIM8 GTPBP6 MYCBP2 ZNF224 PTK2 NELL2 WIZ PTPRK CLTC MAP3K11 WASHC4 ARFGEF2 SORBS1 CACHD1 INTS8 MSTO1 RBCK1 SPTBN4 FAIM LRP1 WDFY3 POLDIP2

3.11e-0612852082335914814
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

CLTCL1 MYCBP2 RPN1 PTK2 HNRNPU KIDINS220 CLTC DOCK7 LRP6

3.92e-06202208924639526
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

INTS1 CGN SORCS2 SIPA1L2 DOCK6 TECPR1 CHD7 SORBS1

4.21e-06153208810718198
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

DCAKD MYCBP2 BCKDHB DBT SORT1 PTPN11 WIZ PTPRK CGN CLTC HERC1 HSPA6 CACHD1 PPEF1 IGBP1 TBC1D31 PDP1 LRP6 UBR3 PHLPP2

5.68e-0610492082027880917
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

ANKRD13B OBSCN ERMN SORT1 PTPN11 XPO5 HSPA6 DPP4 EP400 UBE3B ARFGEF2 EPB41L5 FRRS1 NUP188

8.72e-065642081421565611
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

TRPM4 ATP7B HSP90AB4P INTS1 SORT1 PTPN11 MDN1 XPO5 PVR HERC1 DOCK6 HSPA6 DYNC2H1 ARFGEF2 ALG11 INTS8 NUP188 WDFY3 PRRC1

2.33e-0510612081933845483
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

OBSCN DNAH5 EPB41L5 CACHD1 SLC7A14 SPTBN4

3.36e-05101208610997877
Pubmed

Structural and functional consequences of tyrosine phosphorylation in the LRP1 cytoplasmic domain.

PTPN11 LRP1

3.56e-052208218381291
Pubmed

A giant protein that stimulates guanine nucleotide exchange on ARF1 and Rab proteins forms a cytosolic ternary complex with clathrin and Hsp70.

CLTC HERC1

3.56e-05220829233772
Pubmed

Maple syrup urine disease: identification and carrier-frequency determination of a novel founder mutation in the Ashkenazi Jewish population.

BCKDHB DBT

3.56e-052208211509994
Pubmed

Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels.

CACNA1A CACNA1B

3.56e-052208223426690
Pubmed

Disruption of the meprin alpha and beta genes in mice alters homeostasis of monocytes and natural killer cells.

MEP1A MEP1B

3.56e-052208219110362
Pubmed

Targeted disruption of the meprin beta gene in mice leads to underrepresentation of knockout mice and changes in renal gene expression profiles.

MEP1A MEP1B

3.56e-052208212556482
Pubmed

Mammalian alpha-keto acid dehydrogenase complexes: gene regulation and genetic defects.

BCKDHB DBT

3.56e-05220827672509
Pubmed

Meprin metalloproteases: Molecular regulation and function in inflammation and fibrosis.

MEP1A MEP1B

3.56e-052208228502593
Pubmed

Meprin-β activity modulates the β-catalytic subunit of protein kinase A in ischemia-reperfusion-induced acute kidney injury.

MEP1A MEP1B

3.56e-052208232174142
Pubmed

The tyrosine phosphatase SHP2 regulates focal adhesion kinase to promote EGF-induced lamellipodia persistence and cell migration.

PTK2 PTPN11

3.56e-052208223512980
Pubmed

Expression and distribution of meprin protease subunits in mouse intestine.

MEP1A MEP1B

3.56e-05220828660687
Pubmed

Tethering soluble meprin α in an enzyme complex to the cell surface affects IBD-associated genes.

MEP1A MEP1B

3.56e-052208230916990
Pubmed

Synthetic Aβ oligomers (Aβ(1-42) globulomer) modulate presynaptic calcium currents: prevention of Aβ-induced synaptic deficits by calcium channel blockers.

CACNA1A CACNA1B

3.56e-052208223376566
Pubmed

The alpha subunit of meprin A. Molecular cloning and sequencing, differential expression in inbred mouse strains, and evidence for divergent evolution of the alpha and beta subunits.

MEP1A MEP1B

3.56e-05220821374387
Pubmed

Poliovirus entry into human brain microvascular cells requires receptor-induced activation of SHP-2.

PTPN11 PVR

3.56e-052208217717529
Pubmed

Meprin A metalloproteases enhance renal damage and bladder inflammation after LPS challenge.

MEP1A MEP1B

3.56e-052208218971209
Pubmed

Focal Adhesion Kinase-Dependent Role of the Soluble Form of Neurotensin Receptor-3/Sortilin in Colorectal Cancer Cell Dissociation.

PTK2 SORT1

3.56e-052208227834811
Pubmed

CaV 2.1 α1  subunit motifs that control presynaptic CaV 2.1 subtype abundance are distinct from CaV 2.1 preference.

CACNA1A CACNA1B

3.56e-052208238155373
Pubmed

The NLRP1 inflammasomes.

CASP1 NLRP1

3.56e-052208225879281
Pubmed

A role for CAP, a novel, multifunctional Src homology 3 domain-containing protein in formation of actin stress fibers and focal adhesions.

PTK2 SORBS1

3.56e-05220829461600
Pubmed

Isoform-specific interactions between meprin metalloproteases and the catalytic subunit of protein kinase A: significance in acute and chronic kidney injury.

MEP1A MEP1B

3.56e-052208225354939
Pubmed

A highly conserved Toxo1 haplotype directs resistance to toxoplasmosis and its associated caspase-1 dependent killing of parasite and host macrophage.

CASP1 NLRP1

3.56e-052208224699513
Pubmed

Membrane association and oligomeric organization of the alpha and beta subunits of mouse meprin A.

MEP1A MEP1B

3.56e-05220828195177
Pubmed

SH2 domain-containing protein tyrosine phosphatase 2 and focal adhesion kinase protein interactions regulate pulmonary endothelium barrier function.

PTK2 PTPN11

3.56e-052208225317600
Pubmed

Structure of the NLRP1 caspase recruitment domain suggests potential mechanisms for its association with procaspase-1.

CASP1 NLRP1

3.56e-052208223508996
Pubmed

Metalloproteases meprin α and meprin β are C- and N-procollagen proteinases important for collagen assembly and tensile strength.

MEP1A MEP1B

3.56e-052208223940311
Pubmed

Functional coupling between Piezo1 and TRPM4 influences the electrical activity of HL-1 atrial myocytes.

TRPM4 PIEZO1

3.56e-052208238098265
Pubmed

Characterization of a second human clathrin heavy chain polypeptide gene (CLH-22) from chromosome 22q11.

CLTCL1 CLTC

3.56e-05220828733129
Pubmed

The structural genes, MEP1A and MEP1B, for the alpha and beta subunits of the metalloendopeptidase meprin map to human chromosomes 6p and 18q, respectively.

MEP1A MEP1B

3.56e-05220827774936
Pubmed

Low density lipoprotein receptor related protein 1 and 6 gene variants and ischaemic stroke risk.

LRP1 LRP6

3.56e-052208226031789
Pubmed

Molecular characterization of maple syrup urine disease patients from Tunisia.

BCKDHB DBT

3.56e-052208223313820
Pubmed

Meprin β contributes to collagen deposition in lung fibrosis.

MEP1A MEP1B

3.56e-052208228059112
Pubmed

Polarised expression of human intestinal N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase (human meprin) alpha and beta subunits in Madin-Darby canine kidney cells.

MEP1A MEP1B

3.56e-05220829288916
Pubmed

Human mutations in integrator complex subunits link transcriptome integrity to brain development.

INTS1 INTS8

3.56e-052208228542170
Pubmed

Balance of meprin A and B in mice affects the progression of experimental inflammatory bowel disease.

MEP1A MEP1B

3.56e-052208221071511
Pubmed

Identification of the cysteine residues implicated in the formation of alpha 2 and alpha/beta dimers of rat meprin.

MEP1A MEP1B

3.56e-05220828760356
Pubmed

CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.

CLTCL1 CLTC

3.56e-052208229097553
Pubmed

A novel meprin beta' mRNA in mouse embryonal and human colon carcinoma cells.

MEP1A MEP1B

3.56e-05220828567689
Pubmed

Secretion of human meprin from intestinal epithelial cells depends on differential expression of the alpha and beta subunits.

MEP1A MEP1B

3.56e-05220829914532
Pubmed

SHP-2 regulates myogenesis by coupling to FAK signaling pathway.

PTK2 PTPN11

3.56e-052208219698715
Pubmed

Focal adhesion kinase is a substrate and downstream effector of SHP-2 complexed with Helicobacter pylori CagA.

PTK2 PTPN11

3.56e-052208216354697
Pubmed

Immunohistochemical localization of the metalloproteinase meprin in salivary glands of male and female mice.

MEP1A MEP1B

3.56e-05220821701182
Pubmed

The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step.

CLTCL1 CLTC

3.56e-052208220065094
Pubmed

Newly identified exons encoding novel variants of p94/calpain 3 are expressed ubiquitously and overlap the alpha-glucosidase C gene.

GANC CAPN3

3.56e-052208214675785
Pubmed

Regulation of adhesion dynamics by calpain-mediated proteolysis of focal adhesion kinase (FAK).

PTK2 CAPN2

3.56e-052208220150423
Pubmed

The alpha and beta subunits of the metalloprotease meprin are expressed in separate layers of human epidermis, revealing different functions in keratinocyte proliferation and differentiation.

MEP1A MEP1B

3.56e-052208217195012
Pubmed

C-terminal binding protein-2 regulates response of epithelial ovarian cancer cells to histone deacetylase inhibitors.

HDAC9 CTBP2

3.56e-052208222945647
Pubmed

Developmental expression of meprin metalloprotease subunits in ICR and C3H/He mouse kidney and intestine in the embryo, postnatally and after weaning.

MEP1A MEP1B

3.56e-052208211267665
Pubmed

Def defines a conserved nucleolar pathway that leads p53 to proteasome-independent degradation.

CAPN3 UTP25

3.56e-052208223357851
Pubmed

Homo- and heterotetrameric forms of the membrane-bound metalloendopeptidases meprin A and B.

MEP1A MEP1B

3.56e-05220821929422
Pubmed

p125FAK tyrosine phosphorylation and focal adhesion assembly: studies with phosphotyrosine phosphatase inhibitors.

PTK2 PTPN11

3.56e-05220827589239
Pubmed

Cloning of the PABA peptide hydrolase alpha subunit (PPH alpha) from human small intestine and its expression in COS-1 cells.

MEP1A MEP1B

3.56e-05220828262185
Pubmed

Expression analysis of P/Q-type Ca2+ channel alpha 1A subunit mRNA in olfactory mitral cell in N-type Ca2+ channel alpha 1B subunit gene-deficient mice.

CACNA1A CACNA1B

3.56e-052208215050706
Pubmed

Phosphorylation of Def Regulates Nucleolar p53 Turnover and Cell Cycle Progression through Def Recruitment of Calpain3.

CAPN3 UTP25

3.56e-052208227657329
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

SETX HSP90AB4P GTPBP6 MYCBP2 RPN1 ERAP1 LAMC3 GALNT7 ELAC2 PHGDH HNRNPU KIDINS220 XPO5 PVR CLTC BRAT1 HSPA6 POLRMT DERA WDR6 NUP188

3.75e-0512972082133545068
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

MYCBP2 WIZ HSPA6 POLRMT CHD7 MSTO1 WDR6 TLE1 DOCK7 LRP1 CTBP2

4.84e-054182081134709266
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

SETX RBM10 INTS1 PHGDH HNRNPU MDN1 WIZ XPO5 HSPA6 ARFGEF2 CHD7 INTS8 ORC2

5.43e-055822081320467437
Pubmed

Interaction network of human early embryonic transcription factors.

RPN1 DBT HIRA SORT1 WIZ EP400 CHD7 WDR6 TLE1 CTBP2

5.54e-053512081038297188
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH5 DYNC2H1 DNAH12

7.31e-051420839373155
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ABR MYCBP2 TENM2 PTK2 HNRNPU HIRA MDN1 WIZ CLTC CACNA1A CHD7 SORBS1 SPTBN4 DOCK7 LRP1 CTBP2 WDFY3

7.56e-059632081728671696
Pubmed

A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins.

HNRNPU CLTC HSPA6 IGBP1

7.82e-0538208418247557
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SETX SUSD6 PIEZO1 ADGRV1 TPCN1 FAM149B1 DOCK6 WASHC4 EP400 CACHD1 PLCH2 NUP188

9.10e-055292081214621295
Pubmed

Meprin metalloproteases inactivate interleukin 6.

MEP1A MEP1B

1.06e-043208224474695
Pubmed

Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis.

CLTCL1 CLTC

1.06e-043208219509056
Pubmed

Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation.

CASP1 NLRP1

1.06e-043208225744023
Pubmed

Munc13-3 Is Required for the Developmental Localization of Ca2+ Channels to Active Zones and the Nanopositioning of Cav2.1 Near Release Sensors.

CACNA1A CACNA1B

1.06e-043208229466725
Pubmed

Purinergic neurotransmission receptor P2X4 silencing alleviates intracerebral hemorrhage-induced neuroinflammation by blocking the NLRP1/Caspase-1 pathway.

CASP1 NLRP1

1.06e-043208237652931
Pubmed

Proteolytic processing of galectin-3 by meprin metalloproteases is crucial for host-microbiome homeostasis.

MEP1A MEP1B

1.06e-043208237000885
Pubmed

NLRP1 is an inflammasome sensor for Toxoplasma gondii.

CASP1 NLRP1

1.06e-043208224218483
Pubmed

Three novel mutations of the BCKDHA, BCKDHB and DBT genes in Chinese children with maple syrup urine disease.

BCKDHB DBT

1.06e-043208234883003
Pubmed

Molecular and structural analyses of maple syrup urine disease and identification of a founder mutation in a Portuguese Gypsy community.

BCKDHB DBT

1.06e-043208218378174
Pubmed

Poldip2 controls leukocyte infiltration into the ischemic brain by regulating focal adhesion kinase-mediated VCAM-1 induction.

PTK2 POLDIP2

1.06e-043208233692398
Pubmed

Genetic association study of NLRP1, CARD, and CASP1 inflammasome genes with chronic Chagas cardiomyopathy among Trypanosoma cruzi seropositive patients in Bolivia.

CASP1 NLRP1

1.06e-043208229438387
Pubmed

BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module.

ADGRB1 ELMO1

1.06e-043208217960134
Pubmed

Maple Syrup Urine Disease

BCKDHB DBT

1.06e-043208220301495
Pubmed

The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.

CACNA1A CACNA1B

1.06e-043208238996073
Pubmed

Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles.

DYNC2H1 DNAH12

1.06e-04320828666668
Pubmed

Three Novel Genetic Variants in the FAM110D, CACNA1A, and NLRP12 Genes Are Associated With Susceptibility to Hypertension Among Dai People.

CACNA1A NLRP1

1.06e-043208233621312
Pubmed

NMDA and HIV-1 coat protein, GP120, produce necrotic but not apoptotic cell death in human CHP100 neuroblastoma cultures via a mechanism involving calpain.

CAPN2 CAPN3

1.06e-04320828954122
Pubmed

A new autoinflammatory and autoimmune syndrome associated with NLRP1 mutations: NAIAD (NLRP1-associated autoinflammation with arthritis and dyskeratosis).

CASP1 NLRP1

1.06e-043208227965258
Pubmed

Villin and actin in the mouse kidney brush-border membrane bind to and are degraded by meprins, an interaction that contributes to injury in ischemia-reperfusion.

MEP1A MEP1B

1.06e-043208221795642
Pubmed

Description of the mutations in 15 subjects with variant forms of maple syrup urine disease.

BCKDHB DBT

1.06e-043208217922217
Pubmed

Molecular genetics of maple syrup urine disease in the Turkish population.

BCKDHB DBT

1.06e-043208219480318
Pubmed

Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation.

CASP1 NLRP1

1.06e-043208217349957
Pubmed

Molecular moieties masking Ca2+-dependent facilitation of voltage-gated Cav2.2 Ca2+ channels.

CACNA1A CACNA1B

1.06e-043208229208674
InteractionTOP3B interactions

TRPM4 CLTCL1 ABR GTPBP6 MYCBP2 PIEZO1 INTS1 OBSCN LAMC3 ELAC2 PHGDH HNRNPU HIRA TPCN1 TINAGL1 HEG1 MDN1 WIZ XPO5 MAP3K11 HERC1 SIPA1L2 BRAT1 DOCK6 WDR24 ANKRD13D HSPG2 EP400 UBE3B AOC2 POLRMT ARFGEF2 HEYL NUP188 WDFY3 MAPKBP1

8.19e-07147020636int:TOP3B
InteractionSLAMF1 interactions

ERAP1 INTS1 ADGRV1 PTPN11 DSTYK ANKRD13D ARFGEF2 CACHD1 NUP188

5.62e-061252069int:SLAMF1
InteractionGPR17 interactions

SETX ERAP1 INTS1 TPCN1 MDN1 XPO5 DSTYK BRAT1 WASHC4 ARFGEF2 MSTO1 UBR3 WDFY3

7.37e-0628320613int:GPR17
InteractionDGCR2 interactions

GTPBP6 INTS1 TPCN1 KIDINS220 MDN1 PTPRK XPO5 DSTYK WASHC4 LEMD2

1.77e-0518120610int:DGCR2
InteractionGRP interactions

MEP1A MEP1B DPP4

2.06e-0562063int:GRP
InteractionDMGDH interactions

HNRNPU DMGDH XPNPEP1

2.06e-0562063int:DMGDH
InteractionLDLRAD4 interactions

KIDINS220 ANKRD13D WASHC4 ARFGEF2 RBCK1 UBR3

3.04e-05592066int:LDLRAD4
InteractionHCST interactions

PIGN INTS1 BCKDHB MDN1 XPO5 DSTYK BRAT1 ALG11 INTS8 WDFY3

5.14e-0520520610int:HCST
GeneFamilyWD repeat domain containing

KATNB1 DMXL1 HIRA HERC1 WDR24 DNAI3 TBC1D31 WDR6 TLE1 GNB5 WDFY3 MAPKBP1

1.27e-0626214412362
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

PTK2 FRMPD2 EPB41L5 MYLIP

6.69e-045014441293
GeneFamilyBone morphogenetic proteins|Astacins

MEP1A MEP1B

9.25e-0461442894
ToppCelldroplet-Liver-nan-3m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF144B HDAC9 ERAP1 ELMO1 ANKRD13D RFX4 GPN2 LRP6

1.47e-07127207839fa20a55de3af1a62ab5dfa4877879db3935ac2
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 HEPHL1 CACNA1B COL9A1 MUC5B TECTA PTCHD4 CNTNAP4

8.60e-071602078c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 HEPHL1 CACNA1B COL9A1 MUC5B TECTA PTCHD4 CNTNAP4

8.60e-07160207825c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

KBTBD3 PIEZO1 GAS6 GPR141 HEG1 ANKRD13D ITLN2 UTP25

1.30e-061692078665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

KBTBD3 PIEZO1 GAS6 GPR141 HEG1 ANKRD13D ITLN2 UTP25

1.30e-0616920786614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD1c+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

RNF144B TRPM4 PLBD1 GLDN PGAM2 VNN1 RAB44 CTBP2

1.48e-061722078200b2e63313b110b8ca59ee5b72c02cc8ed907cd
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

GAS6 TMEM63B SEMA6D CGN HMGCLL1 HSPG2 EPB41L5 ITLN2

2.00e-0617920781603117b52623663458a977c94bf7f9f6c1114b8
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN ADGRV1 CSMD3 DNAH5 COL9A1 MUC5B XIRP2 CNTNAP4

2.45e-0618420782cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN ADGRV1 CSMD3 DNAH5 COL9A1 MUC5B XIRP2 CNTNAP4

2.45e-0618420782b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN ADGRV1 CSMD3 DNAH5 COL9A1 MUC5B XIRP2 CNTNAP4

2.45e-061842078ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYCBP2 DPYSL5 TENM2 SVOP RAB26 CACNA1B SLC7A14 SPTBN4

3.11e-061902078416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYCBP2 DPYSL5 TENM2 SVOP HMGCLL1 CACNA1B PTCHD4 CNTNAP4

3.23e-0619120785d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYCBP2 DPYSL5 TENM2 SVOP HMGCLL1 CACNA1B PTCHD4 CNTNAP4

3.23e-06191207873dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCell(02)_MMP9/10+-(1)_GFP|(02)_MMP9/10+ / shred by cell type by condition

HDAC9 ABR SUSD6 PIEZO1 TINAGL1 PTPRK SMOX MUC5B

4.38e-061992078448ba982be804007f991d469eca9d885b21ae499
ToppCellMacroglial-Oligodendrocytes-OPALIN--|Macroglial / cells hierarchy compared to all cells using T-Statistic

GLDN ELMO1 ERMN SORT1 PTPRK CAPN3 SLC7A14 CNTNAP4

4.54e-06200207826b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCellMacroglial-Oligodendrocytes-OPALIN---|Macroglial / cells hierarchy compared to all cells using T-Statistic

GLDN ELMO1 ERMN SORT1 PTPRK CAPN3 SLC7A14 CNTNAP4

4.54e-0620020781314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCellMacroglial-Oligodendrocytes-OPALIN|Macroglial / cells hierarchy compared to all cells using T-Statistic

GLDN ELMO1 ERMN SORT1 PTPRK CAPN3 SLC7A14 CNTNAP4

4.54e-0620020785f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCellMacroglial-Oligodendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

GLDN ELMO1 ERMN SORT1 PTPRK CAPN3 SLC7A14 CNTNAP4

4.54e-0620020784dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCellMacroglial-Oligodendrocytes-OPALIN-|Macroglial / cells hierarchy compared to all cells using T-Statistic

GLDN ELMO1 ERMN SORT1 PTPRK CAPN3 SLC7A14 CNTNAP4

4.54e-0620020788b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCellMacroglial-Oligodendrocytes-OPALIN----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

GLDN ELMO1 ERMN SORT1 PTPRK CAPN3 SLC7A14 CNTNAP4

4.54e-062002078272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCellE16.5-samps-Myeloid-Fetal_macrophage-Proliferative_Myeloid|E16.5-samps / Age Group, Lineage, Cell class and subclass

PLBD1 GPR141 FPR1 CASP1 ORAI2 RAB44 FRRS1

7.25e-061522077e427758a6e39052616a0d8ecec0c1299e81d1d3c
ToppCellHealthy/Control-CD8+_T_naive|World / Disease group and Cell class

ZNF274 PGAM2 PHGDH NELL2 DPP4 CACHD1 ANO7

9.34e-06158207770680b29428b6bf882b1fae36f924b775961176b
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCAT1 ACSS2 MEP1A MEP1B VNN1 UGT3A2 DMGDH

1.10e-051622077de0fde4310a56dc96bfc134c44d104993526d9bc
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

OBSCN HNRNPU DSTYK KATNIP UBE3B UTP25 WDR6

1.29e-05166207732d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGRV1 PTK2 PTPRK SORCS2 DNAH5 EPB41L5 CACHD1

1.29e-051662077c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCellnormal_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

OBSCN LAMC3 PTK2 TINAGL1 SEMA6D CHD7 HEYL

1.50e-051702077d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRB1 DPYSL5 ADGRV1 NELL2 RAB26 PTCHD4 SLC7A14

1.75e-051742077271c51d220842402975d97c86c9acfdbdf62a32c
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CERKL PGAM2 SVOP RAB26 CACNA1A SLC7A14 SPTBN4

1.75e-0517420779f114e61458659005b6d0b4aa30a7a059e7aa5c6
ToppCellnormal_Lung-Fibroblasts-Pericytes|normal_Lung / Location, Cell class and cell subclass

GAS6 OBSCN LAMC3 PTK2 TINAGL1 SEMA6D HEYL

2.25e-051812077f74941e49950027360d71ea3b205fc20c6929766
ToppCellwk_15-18-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CERKL PGAM2 SVOP RAB26 PTCHD4 SLC7A14 SPTBN4

2.42e-0518320778820cfed27b292bc0bc9cde4005219ed41900552
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

CPAMD8 ADGRV1 PTPRK SORCS2 DNAH5 EPB41L5 CACHD1

2.59e-051852077673f0c688ae6984bc8027df2da335787924f4137
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

CPAMD8 ADGRV1 PTK2 PTPRK SORCS2 EPB41L5 LRP6

2.59e-05185207798b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PTK2 ELMO1 PTPRK DPP4 SORBS1 MYLIP LRP1

2.59e-0518520771d874608aa2062024323512f68889219471b2f00
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CERKL MYCBPAP DNAH5 DYNC2H1 FRMPD2 DNAI3 DNAH12

2.59e-0518520775e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MYCBP2 DPYSL5 SVOP CACNA1B CDH22 WDR6 CNTNAP4

2.87e-051882077b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

GALNT7 DSTYK ARHGEF9 ACCS TLE1 CTBP2 PHLPP2

3.18e-0519120772b427741a58921e161101a282d1fe526cd9e760d
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

HDAC9 GAS6 ADGRB1 LAMC3 TINAGL1 KCND2 HEYL

3.28e-05192207755f95454399fd533df75db06584eaa48d6ee3830
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF274 PTPRK CHD7 ORAI2 TCL1B TLE1 GNB5

3.28e-051922077ef86d82e4f04f9f54e821ef496d70fc81072d773
ToppCell343B-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TMEM63B ELAC2 DSTYK HSPA6 ARL5B TBC1D31 POLR3E

3.28e-051922077445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

HDAC9 GAS6 ADGRB1 LAMC3 TINAGL1 KCND2 HEYL

3.28e-0519220775000440dc1ed17e7474d340921bdff945646f27e
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-goblet|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACSS2 FER1L6 RAB26 MUC5B ITLN2 TDRD7 ANO7

3.39e-051932077402aad2f9e789ad1f2e1536cdc9ce61de7625427
ToppCellURO|World / Disease, Lineage and Cell Type

RNF144B PLBD1 BCAT1 VNN1 CLTC FPR1 LRP1

3.39e-051932077421dc0996c6c973f88e90197b651255ae4dd13a2
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CERKL ADGRV1 DNAH5 DYNC2H1 FRMPD2 CACHD1 DNAI3

3.39e-051932077ea345d34440b25f65358a53dc72831998d1c3620
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

FAXDC2 PTK2 PTPRK ARFGEF2 EPB41L5 FRRS1 LRP6

3.39e-051932077503a979328c68b096680b71359a26f02fafdff35
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RNF144B CPAMD8 ABR ELMO1 HEG1 HSPG2 NLRP1

3.39e-0519320770b328f725f6feba263783eaca60c142e80df90f3
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACSS2 FER1L6 RAB26 MUC5B ITLN2 TDRD7 ANO7

3.39e-0519320777ee3b1ef5c455f321b4e154ae62c69543fe9b30e
ToppCellsevere_influenza-B_naive|severe_influenza / disease group, cell group and cell class (v2)

ZNF274 PTPRK CHD7 ORAI2 TCL1B TLE1 GNB5

3.51e-0519420777c1e9ce5de3bb1657a67010de673c8bb60129cb6
ToppCellHealthy_donor-B_naive|World / disease group, cell group and cell class (v2)

ZNF274 PTPRK CHD7 ORAI2 TCL1B TLE1 GNB5

3.62e-051952077c66bbfdf0091cc62aa50edfa88820bbda191b7bb
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RNF144B HDAC9 ABR BCAT1 ELMO1 SLC41A2 LRP1

3.62e-051952077247803cf58c6d9c561a52aa34e581188ddad197e
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GAS6 TMEM63B CGN HSPG2 CAPN2 EPB41L5 ITLN2

3.62e-0519520772a1863f4b9fe73c30b0b1acf9b12fc98ef65040f
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GAS6 TMEM63B CGN HSPG2 CAPN2 EPB41L5 ITLN2

3.62e-05195207768f4cc84b5ae7f4159b780c78e4b66c94211779a
ToppCellAT1_cells|World / lung cells shred on cell class, cell subclass, sample id

GAS6 HEG1 SEMA6D CGN HSPG2 EPB41L5 ITLN2

3.62e-051952077792d6a49b0a875a00569071183d195287a9925c5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABR ELMO1 HEG1 DOCK6 HSPG2 NLRP1 TNXB

3.74e-0519620778ad8efb631164b46f0c082572270188e5ead20bf
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GAS6 TMEM63B CGN HSPG2 CAPN2 EPB41L5 ITLN2

3.74e-051962077eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABR ELMO1 HEG1 DOCK6 HSPG2 NLRP1 TNXB

3.74e-0519620779606ea7e42f707e69ea891b3521037613b9675f5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABR ELMO1 HEG1 DOCK6 HSPG2 NLRP1 TNXB

3.87e-051972077cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellAT1_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

GAS6 SEMA6D CGN HSPG2 CAPN2 EPB41L5 ITLN2

3.87e-05197207780d81be244c94c435accb643449b4ce6a3462c7f
ToppCellnormal_Lung-Epithelial_cells-AT1|Epithelial_cells / Location, Cell class and cell subclass

GAS6 HEG1 SEMA6D HSPG2 CAPN2 EPB41L5 ITLN2

3.87e-0519720777d19b93d6853828e2a036e37c4887edb1de4503c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABR ELMO1 HEG1 DOCK6 HSPG2 NLRP1 TNXB

3.87e-051972077412cb5f37df57121ddd1492021445479c7cbccbf
ToppCellCaecum-(6)_Macrophage-(61)_LYVE1_Macrophage|Caecum / shred on region, Cell_type, and subtype

GLDN PVR SIPA1L2 FPR1 LRP1 CTBP2 WDFY3

3.99e-051982077e684c3934c163aef4d284b69435832d2c9614f2a
ToppCellCaecum-Macrophage-LYVE1_Macrophage|Caecum / Region, Cell class and subclass

GLDN PVR SIPA1L2 FPR1 LRP1 CTBP2 WDFY3

3.99e-051982077a92c0cacb775aca6bbb302bd9e22c081a112a44d
ToppCell5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RNF144B CPAMD8 GAS6 TINAGL1 HEG1 HSPG2 SELENON

3.99e-0519820778a55589b9244283e4b0b423a4a6d6202e8e0fec9
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FAXDC2 PTK2 ERMN PTPRK SORCS2 CAPN3 LRP6

4.12e-0519920775d2e85e40b6b52b1809e680b952913d77215b3d0
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PLBD1 BCAT1 SORT1 VNN1 FPR1 LRP1 WDFY3

4.12e-05199207780ed217d28ba1c07facd0e103c25a02658dd848d
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FAXDC2 PTK2 ERMN PTPRK SORCS2 CAPN3 LRP6

4.12e-0519920776fb5f931e6217142de38c1fffc011e63bda4772b
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FAXDC2 PTK2 ERMN PTPRK SORCS2 CAPN3 LRP6

4.12e-0519920779dd4b17fb8c70ab9e126b23b72600463f3db832d
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FAXDC2 PTK2 ERMN PTPRK SORCS2 CAPN3 LRP6

4.12e-0519920771bb5797e8e0552bf9b44bf4c958d1aa6dbe6c756
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

GAS6 OBSCN LAMC3 TINAGL1 SEMA6D DOCK6 HEYL

4.26e-0520020770c648941447c738caf62f2d71e296d6cca492c8b
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

MYCBP2 CSMD3 TENM2 HERC1 CACNA1A CACNA1B SPTBN4

4.26e-05200207748d801219bc771d6c7e151dc88ca4c179988de85
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GAS6 OBSCN LAMC3 TINAGL1 SEMA6D DOCK6 HEYL

4.26e-052002077522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

GAS6 OBSCN LAMC3 TINAGL1 SEMA6D DOCK6 HEYL

4.26e-05200207794f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HDAC9 ABR MEP1A VNN1 FPR1 RENBP LRP1

4.26e-05200207778d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCellCiliated_cells-A-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

KCND2 COL9A1 FRMPD2 MUC5B DNAI3 DNAH12

6.26e-05146207620f080318e9cbfd9b8b90a5e9f704d6d85b969ee
ToppCell10x5'-bone_marrow-Myeloid_Monocytic-Cycling_mono|bone_marrow / Manually curated celltypes from each tissue

PLBD1 GLDN GAS6 FPR1 LRP1 WDFY3

6.75e-051482076de35eeefad0e27a0d127e2e4bedead2bddb75152
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CSMD3 CACNA1A CACNA1B ADAM29 CNTNAP4 CYP4F22

7.27e-0515020760205318a870e091add66ee4305747dda9f51510d
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLBD1 GPR141 SLC41A2 PTPRK DYNC2H1 FPR1

8.12e-0515320760ef7c45cdd854c79e527006034029767f8e108b2
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

HEG1 KCND2 SORCS2 PPEF1 HEYL CRYGN

8.41e-051542076511923b27469ea20f8bd82a9ec27119a6e884644
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KATNB1 CSMD3 LACTBL1 CACNA1A COL9A1 SPTBN4

8.72e-05155207651f6447945389649d99dcf7603b396195c631ead
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KATNB1 CSMD3 LACTBL1 CACNA1A COL9A1 SPTBN4

8.72e-05155207623dc71cab28094ca0ac4d2baf4e24871ed107781
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

CSMD3 TENM2 KCND2 CACNA1A CACNA1B XIRP2

1.00e-0415920765335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellAdult-Immune-mast_cell-D175|Adult / Lineage, Cell type, age group and donor

ZNF274 ADGRB1 CACNA1A POLRMT RAB44 PLCH2

1.00e-0415920769f53fe2e0f25448d62a591c8e528e9a49b5400d5
ToppCelldroplet-Marrow-BM-30m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLBD1 GPR141 TINAGL1 SMOX CAPN2 LRP1

1.04e-041602076822adcf5f9208f305cafffd8ed97f3a061e82b03
ToppCellHealthy/Control-CD8+_T_naive|Healthy/Control / Disease group and Cell class

PGAM2 PHGDH NELL2 SORBS1 CACHD1 ANO7

1.04e-041602076e1386c21fcbbf57fa32d8bdfba3cb1887477ff73
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TINAGL1 PTPRK ZC3H12A ITLN2 CYP4F22 PHLPP2

1.07e-0416120760d863d7d369391dd6148e1de6d6f8033dcb8fe0f
ToppCelldroplet-Marrow-BM-30m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLBD1 GPR141 TINAGL1 SMOX CAPN2 LRP1

1.11e-04162207676e289ad9fd3694f77fd0d19e74c1cb8e87b8094
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ELMO1 HEG1 DOCK6 HSPA6 HSPG2 TNXB

1.11e-0416220765428c9fdb816f564395ebb4520448e5f3a42b025
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

CSMD3 NELL2 CACNA1A ADAM29 CNTNAP4 CYP4F22

1.15e-04163207619c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

CPAMD8 ADGRV1 SORCS2 DNAH5 EPB41L5 CACHD1

1.15e-041632076e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLBD1 GPR141 FPR1 ADAM29 SPTBN4 CTBP2

1.19e-04164207610741c7706a37b24aa08a300b27d60d6b8600167
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLBD1 GPR141 FPR1 ADAM29 SPTBN4 CTBP2

1.19e-0416420767077683afee91828ad2b95e0f81c2b27aae0f831
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GLDN DPYSL5 CGN XIRP2 CNTNAP4 ANO7

1.27e-0416620766a6ed5c7a43fee9a8a9be42dfa99303815b8e8ef
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

CERKL MYCBPAP DNAH5 DYNC2H1 DNAI3 DNAH12

1.31e-04167207626cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellfacs-Brain_Myeloid-Hippocampus-24m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSMD3 PHGDH TPCN1 MEP1A HEPHL1 LRP1

1.31e-041672076a21a2b301d0a3d7a41e605f7a3c37548962a331d
ToppCellfacs-Brain_Myeloid-Hippocampus-24m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSMD3 PHGDH TPCN1 MEP1A HEPHL1 LRP1

1.31e-0416720760e746483773bde6582874a33591ab2a578d724eb
ToppCellfacs-Brain_Myeloid-Hippocampus-24m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSMD3 PHGDH TPCN1 MEP1A HEPHL1 LRP1

1.31e-0416720767f3224af9b30082b927a822b91f96e0c88151b4e
ToppCellASK428-Immune-Mast_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

GPR141 TENM2 TPCN1 DSTYK PNMA3 DPP4

1.36e-041682076c399fcb4d1d0be48026c2ecabc34a5935e7adf73
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD13B PIGN PGAM2 WIZ ARFGEF2 GNB5

1.36e-041682076b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RNF144B CPAMD8 ELMO1 HEG1 HEPHL1 HSPG2

1.40e-041692076c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

CPAMD8 ADGRV1 PTK2 PTPRK SORCS2 CACHD1

1.45e-041702076269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCellfacs-Brain_Myeloid-Hippocampus-24m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSMD3 PHGDH TPCN1 MEP1A HEPHL1 LRP1

1.45e-041702076b4f2c05db2c2591561fd42febc72eed3b5e8f9fb
DrugIoversol [87771-40-2]; Down 200; 5uM; MCF7; HT_HG-U133A

ZSWIM8 SETX SUSD6 BCKDHB PTK2 PHGDH PTPN11 KIDINS220 EP400 UTP25 GNB5 LRP6

2.43e-07196206125326_DN
DrugFrie Mao 1-43

TRPM4 CLTCL1 NMUR1 ADGRV1 SORT1 CGN CLTC

1.29e-06612067CID002733618
Drug2-aminoresorcinol

GANC CAPN3 AOC2

2.90e-0642063CID000069450
DrugOne-time

CLTCL1 KCND2 CLTC HTR1D RENBP POLR3E

4.56e-06482066CID000040813
DrugChlorzoxazone [95-25-0]; Down 200; 23.6uM; HL60; HG-U133A

RBM10 BCAT1 DBT HNRNPU DMXL1 EP400 WDR6 GNB5 MYLIP NUP188

1.15e-05194206101416_DN
DrugChlortetracycline hydrochloride [64-72-2]; Down 200; 7.8uM; HL60; HG-U133A

PIGN RBM10 DBT ELAC2 HNRNPU ZC3H12A EP400 WDR6 NUP188 MAPKBP1

1.15e-05194206102042_DN
DrugFlurbiprofen [5104-49-4]; Down 200; 16.4uM; HL60; HT_HG-U133A

DCAKD KATNB1 GAS6 BCKDHB DBT WIZ DSTYK CACNA1A NLRP1 LRP6

1.25e-05196206103095_DN
DrugDeoxycorticosterone [64-85-7]; Down 200; 12.2uM; HL60; HT_HG-U133A

HDAC9 SUSD6 PIEZO1 KATNB1 BCKDHB PTPN11 KIDINS220 UBE3B NLRP1 ORAI2

1.31e-05197206103099_DN
Drugquinocetone

LAMC3 ADGRV1 ACSS2 HSPA6 HSPG2 DYNC2H1 SLC7A14 DNAH12 PLCH2 LRP1 LY75

1.72e-0524820611ctd:C502851
DrugCP-80

CLTCL1 CLTC CACNA1A CACNA1B FPR1

1.73e-05362065CID000452640
Drugcyclopropavir

CLTCL1 PTPN11 PVR CLTC PPEF1

1.99e-05372065CID003006048
DrugEGTA-AM

CGN CACNA1A CACNA1B CASP1 NLRP1 TECTA

2.06e-05622066CID000121907
DrugNa 7

CLTCL1 BCKDHB CLTC

3.95e-0582063CID000446006
DrugMIBK

KLHL2 CLTCL1 BCKDHB PTPN11 CLTC CACNA1B

4.13e-05702066CID000007909
DrugFenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; MCF7; HT_HG-U133A

TRPM4 INTS1 HIRA WIZ DSTYK KATNIP HECTD3 EPB41L5 LRP6

6.89e-0519320693412_DN
Druglomofungin

GANC CAPN3 POLRMT POLR3E

7.09e-05252064CID005351222
DrugProadifen hydrochloride [62-68-0]; Down 200; 10.2uM; HL60; HT_HG-U133A

BCKDHB HNRNPU MEP1B WIZ PVR DOCK6 CAPN2 NLRP1 NUP188

7.46e-0519520692707_DN
DrugHomatropine hydrobromide (R,S) [51-56-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A

ERAP1 FAXDC2 BCKDHB DBT SORT1 PVR HSPG2 EP400 TLE1

7.76e-0519620691684_UP
DrugNaltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; PC3; HT_HG-U133A

PLBD1 ABR BCKDHB HEG1 EP400 CAPN2 CASP1 NLRP1 LRP6

7.76e-0519620692047_UP
DrugCephalothin sodium salt [58-71-9]; Up 200; 9.6uM; PC3; HT_HG-U133A

FBXO40 CLTCL1 LAMC3 SORT1 VNN1 DSTYK PVR NLRP1 MUC5B

7.76e-0519620694482_UP
DrugChlorogenic acid [327-97-9]; Up 200; 11.2uM; PC3; HT_HG-U133A

FBXO40 CLTCL1 ERAP1 ADGRB1 HEG1 WIZ VNN1 EPB41L5 TLE1

8.07e-0519720694024_UP
DrugAllantoin [97-59-6]; Up 200; 25.2uM; PC3; HT_HG-U133A

DCAKD ERAP1 DBT HIRA PTPN11 KIDINS220 DPP4 NLRP1 WDFY3

8.07e-0519720691800_UP
DrugMetronidazole [443-48-1]; Down 200; 23.4uM; HL60; HG-U133A

RBM10 DMXL1 HIRA ZC3H12A EP400 DERA UTP25 WDFY3 PRRC1

8.07e-0519720692003_DN
Drugflavocommelin

GANC CAPN3

8.15e-0522062CID005317357
DrugBadg

CLTCL1 CLTC

8.15e-0522062CID000125951
Drugugandensolide

GANC CAPN3

8.15e-0522062CID012444581
Drug4-methylbenzene-1,2,3-triol

GANC CAPN3

8.15e-0522062CID000156015
Drug(5aS,9aS)-6,6,9a-trimethyl-5,5a,7,8,9,9b-hexahydro-1H-benz[e]isobenzofuran-3-one

GANC CAPN3

8.15e-0522062CID010130877
Drugpereniporin B

GANC CAPN3

8.15e-0522062CID000161192
Drugkengaquinone

GANC CAPN3

8.15e-0522062CID011509704
Drugkenganthranols A

GANC CAPN3

8.15e-0522062CID000636820
DrugAC1LDIKR

GANC CAPN3

8.15e-0522062CID000619164
Drugthiophthalimide

GANC CAPN3

8.15e-0522062CID003032671
Drugaloeresin A

GANC CAPN3

8.15e-0522062CID005317657
DrugN-phenylphthalimide

GANC DPP4 CAPN3

8.36e-05102063CID000068215
Drugacetylaminophenylarsine oxide

CLTCL1 CLTC SMOX

8.36e-05102063CID006337999
DrugL(-)-vesamicol hydrochloride [112709-59-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A

TRPM4 DBT HIRA HEG1 DYNC2H1 CASP1 ORAI2 LRP6 MAPKBP1

8.39e-0519820696497_DN
DrugAzacyclonol [115-46-8]; Down 200; 15uM; HL60; HG-U133A

PIGN RBM10 DBT HNRNPU UBE3B WDR6 MYLIP NUP188 MAPKBP1

8.39e-0519820692020_DN
DrugDanazol [17230-88-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A

GAS6 FAXDC2 PVR DOCK6 DYNC2H1 UBE3B CASP1 LRP6 MAPKBP1

8.39e-0519820691538_DN
DrugMetformin hydrochloride [1115-70-4]; Down 200; 24.2uM; PC3; HT_HG-U133A

ERAP1 KATNB1 DPP4 WASHC4 CASP1 ARFGEF2 ORAI2 FAIM LRP6

8.39e-0519820691816_DN
DrugMethylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; HL60; HT_HG-U133A

DCAKD GAS6 FAXDC2 NELL2 DSTYK PVR ACSBG2 HTR1D RENBP

8.39e-0519820692994_UP
DrugGlycopyrrolate [596-51-0]; Up 200; 10uM; PC3; HT_HG-U133A

ABR LAMC3 VNN1 PVR CACNA1A ZC3H12A CASP1 TLE1 LRP1

8.39e-0519820697386_UP
DrugCefotetan [69712-56-7]; Down 200; 7uM; HL60; HT_HG-U133A

RBM10 KATNB1 HSPG2 EP400 CAPN3 NLRP1 ORAI2 GNB5 WDFY3

8.72e-0519920691319_DN
DrugKanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; MCF7; HT_HG-U133A

ERAP1 FAXDC2 BCKDHB SORT1 WIZ DOCK6 HSPG2 CASP1 SORBS1

8.72e-0519920693224_UP
DrugAmoxicillin [26787-78-0]; Down 200; 11uM; HL60; HT_HG-U133A

SETX BCAT1 BCKDHB DBT HIRA ZC3H12A WDFY3 MAPKBP1 PRRC1

8.72e-0519920691265_DN
DrugBenzocaine [94-09-7]; Up 200; 24.2uM; HL60; HT_HG-U133A

ADGRB1 BCKDHB PGAM2 WIZ DSTYK FAM149B1 PKD1L1-AS1 LRP6 NUP188

9.06e-0520020692167_UP
Drugp-nitrophenyl-alpha-D-glucopyranoside

GANC ADGRV1 CACNA1B DPP4 CAPN2 CAPN3 XPNPEP1

9.09e-051162067CID000065115
DrugArg-pro

CLTCL1 KIDINS220 CLTC DPP4 CASP1 XPNPEP1

1.01e-04822066CID000151003
Diseasecortical thickness

ANKRD13B HDAC9 CPAMD8 MYCBP2 DPYSL5 LAMC3 ADGRV1 TENM2 ELAC2 NELL2 XPO5 DPP4 HSPG2 HTR1D ARFGEF2 CHD7 RFX4 RAB44 DOCK7 LRP1 CTBP2

2.63e-05111320121EFO_0004840
DiseaseMaple syrup urine disease

BCKDHB DBT

1.38e-0432012cv:C0024776
Diseasefamilial hemiplegic migraine 1 (implicated_via_orthology)

CACNA1A CACNA1B

1.38e-0432012DOID:0111181 (implicated_via_orthology)
Diseasemigraine (implicated_via_orthology)

CACNA1A CACNA1B

2.75e-0442012DOID:6364 (implicated_via_orthology)
DiseaseVesico-Ureteral Reflux

DSTYK TNXB

2.75e-0442012C0042580
Diseasealcohol consumption measurement

PIGN ADGRB1 DPYSL5 LAMC3 ADGRV1 GALNT7 CSMD3 TENM2 SEMA6D PTPRK KCND2 DNAH5 SVOP CACNA1A DPP4 UBE3B SELENON DERA CTBP2 PHLPP2

3.41e-04124220120EFO_0007878
Diseasehereditary spastic paraplegia 76 (implicated_via_orthology)

CAPN2 CAPN3

4.56e-0452012DOID:0110821 (implicated_via_orthology)
DiseaseIntermediate Maple Syrup Urine Disease

BCKDHB DBT

4.56e-0452012C1621920
DiseaseClassic Maple Syrup Urine Disease

BCKDHB DBT

4.56e-0452012C0268568
DiseaseIntermittent Maple Syrup Urine Disease

BCKDHB DBT

4.56e-0452012C0268569
DiseaseMaple Syrup Urine Disease, Thiamine Responsive

BCKDHB DBT

4.56e-0452012C0751285
Diseasemaple syrup urine disease (is_implicated_in)

BCKDHB DBT

4.56e-0452012DOID:9269 (is_implicated_in)
Diseaseperipheral arterial disease

HDAC9 CSMD3 PTPN11 SLC8A3

5.06e-04542014EFO_0004265
Diseasepappalysin-1 measurement

RPN1 CHD7

6.80e-0462012EFO_0802845
DiseaseMaple Syrup Urine Disease

BCKDHB DBT

6.80e-0462012C0024776
Diseaseneuritic plaque measurement

HDAC9 ZNF274 LAMC3 GALNT7 PTK2 CACNA1A DYNC2H1 EPB41L5 CDH22

6.91e-043492019EFO_0006798
Diseasecortical surface area measurement

HDAC9 CPAMD8 ABR MYCBP2 DPYSL5 LAMC3 ADGRV1 TENM2 ELAC2 TINAGL1 DSTYK CACNA1A DPP4 HTR1D CAPN2 CHD7 CACHD1 RFX4 CTBP2 TNXB

9.20e-04134520120EFO_0010736
Diseasehereditary ataxia (implicated_via_orthology)

CACNA1A CACNA1B

9.48e-0472012DOID:0050951 (implicated_via_orthology)
Diseaseresting heart rate, chronic obstructive pulmonary disease

ADGRV1 HERC1 LEMD2

1.10e-03302013EFO_0000341, EFO_0004351
DiseaseDisorder of amino acid metabolism

BCKDHB DBT

1.26e-0382012cv:C0002514
Diseaseprostate cancer (implicated_via_orthology)

ELAC2 MEP1A MEP1B

1.46e-03332013DOID:10283 (implicated_via_orthology)
DiseaseGrey matter density measurement

ELAC2 KATNIP LEMD2

1.59e-03342013EFO_0010306
DiseaseGlaucoma

CPAMD8 TDRD7

1.61e-0392012C0017601
DiseaseAlzheimer disease

FBXO40 GPR141 TENM2 ELMO1 DMXL1 TPCN1 SORT1 SIPA1L2 RBCK1 TNXB

1.91e-0348520110MONDO_0004975
DiseaseDisproportionate short stature

PTPN11 HSPG2 COL9A1 DYNC2H1

1.92e-03772014C0878659
DiseaseCataract

CPAMD8 INTS1 TDRD7

2.04e-03372013C0086543
DiseaseColorectal Carcinoma

CPAMD8 ATP7B RBM10 OBSCN CSMD3 UGT3A2 FRMPD2 ADAM29 SLC22A9 CDH22 GNB5 LRP1

3.31e-0370220112C0009402
Diseasetriglyceride measurement, phospholipid measurement

GAS6 DMGDH CAPN3 HEYL DOCK7

3.32e-031462015EFO_0004530, EFO_0004639
DiseaseDiabetic Nephropathy

GAS6 ELMO1 PTPN11

3.36e-03442013C0011881
Diseaselipid measurement, lipoprotein measurement

GAS6 PTPN11 DOCK6 DOCK7

3.38e-03902014EFO_0004529, EFO_0004732
DiseaseFVC change measurement, response to placebo

KATNIP SMOX

3.43e-03132012EFO_0008344, EFO_0010339
Diseaselevel of Phosphatidylinositol (18:1_18:1) in blood serum

DOCK6 DOCK7

3.43e-03132012OBA_2045159
DiseaseProstatic Neoplasms

TRPM4 ATP7B ABR PGAM2 ELAC2 PHGDH PTPRK PVR CHD7 PDP1 CTBP2

3.50e-0361620111C0033578
DiseaseMalignant neoplasm of prostate

TRPM4 ATP7B ABR PGAM2 ELAC2 PHGDH PTPRK PVR CHD7 PDP1 CTBP2

3.50e-0361620111C0376358
DiseaseAutosomal recessive limb-girdle muscular dystrophy

TRAPPC11 CAPN3

3.98e-03142012cv:C2931907
Diseasetriglyceride measurement, alcohol drinking

GAS6 CAPN3 HEYL DOCK7

4.75e-03992014EFO_0004329, EFO_0004530
Diseasetriglyceride measurement, alcohol consumption measurement

GAS6 CAPN3 HEYL DOCK7

5.10e-031012014EFO_0004530, EFO_0007878
DiseaseSpondyloepiphyseal Dysplasia

HSPG2 COL9A1

5.20e-03162012C0038015
Diseaseidiopathic scoliosis (implicated_via_orthology)

KATNB1 PTPN11

5.20e-03162012DOID:0060250 (implicated_via_orthology)
DiseaseSpondyloepiphyseal Dysplasia Tarda, X-Linked

HSPG2 COL9A1

5.20e-03162012C3541456
DiseaseSchwartz-Jampel Syndrome, Type 1

HSPG2 COL9A1

5.20e-03162012C4551479
Diseaseamyloid-beta measurement, Alzheimer's disease biomarker measurement

PIGN MYLIP

5.20e-03162012EFO_0005194, EFO_0006514
DiseaseSchwartz-Jampel Syndrome

HSPG2 COL9A1

5.20e-03162012C0036391
DiseaseMelnick-Needles Syndrome

HSPG2 COL9A1

5.20e-03162012C0025237
Diseasereaction time measurement

FAXDC2 TENM2 PTPN11 SEMA6D PTPRK DPP4 OR5AU1 NLRP1 UTP25 ANO7 PRRC1

5.69e-0365820111EFO_0008393
DiseaseVan Buchem disease

HSPG2 COL9A1

5.87e-03172012C0432272
DiseaseMouth Neoplasms

ATP7B LAMC3 PTK2

5.98e-03542013C0026640
DiseaseMalignant neoplasm of mouth

ATP7B LAMC3 PTK2

5.98e-03542013C0153381
Diseaseapolipoprotein B measurement

GAS6 DPYSL5 ZNF224 PTK2 SORT1 PTPN11 PVR SORCS2 DOCK6 MYLIP DOCK7

6.01e-0366320111EFO_0004615
Diseasebasophil count, eosinophil count

RPN1 ELMO1 MAP3K11 CHD7 TNXB SLC7A10

6.33e-032412016EFO_0004842, EFO_0005090
Diseasebipolar disorder, sex interaction measurement

ADGRB1 SIPA1L2

6.57e-03182012EFO_0008343, MONDO_0004985
Diseaselevel of Phosphatidylinositol (18:0_18:1) in blood serum

DOCK6 DOCK7

6.57e-03182012OBA_2045155
DiseaseDisorder of organic acid metabolism

BCKDHB DBT

6.57e-03182012cv:C1263739

Protein segments in the cluster

PeptideGeneStartEntry
LTSAADIWSHDVMAQ

ABR

816

Q12979
MLSHDNITWIAGAVT

ACSBG2

241

Q5FVE4
SEATIGLHTMWNEHF

ALG11

386

Q2TAA5
SDHTTVHWARFNDIM

ADAM29

566

Q9UKF5
MLLFRSATGEAWHNI

CACNA1A

1746

O00555
GMTERHWEAVFTLQS

EP400

1226

Q96L91
AVMQVFTEWLRDGHA

BRAT1

611

Q6PJG6
AFVELMDHGIVSWDT

ELMO1

161

Q92556
VDTSLLGFEHMTWQR

ANKRD13D

156

Q6ZTN6
HFLMWDIGGQESLRS

ARL5B

61

Q96KC2
TVFTDHMLTVEWSSE

BCAT1

51

P54687
QMWLHLQTDESVGSV

CSMD3

636

Q7Z407
HTAWYSEQASLEMRE

CTBP2

321

P56545
DPQRTHVMWATSKDF

ACCS

311

Q96QU6
VHRLTESMTHWGQEL

SLC7A10

476

Q9NS82
TEAWQSYMAVTGHLR

ADGRB1

1031

O14514
TASQVSVHIGMDDRW

ATP7B

1396

P35670
TGDTTFSWHREDMQE

FCRL4

316

Q96PJ5
SVQWETVSETAFGMR

ADGRV1

3236

Q8WXG9
LETSTSSFEHRWMVI

ARFGEF2

486

Q9Y6D5
VRNEVMATSHVTDEW

CACHD1

701

Q5VU97
MTETAWTIIQHNGSD

CNTNAP4

626

Q9C0A0
SDDRIWVTEHFSGIM

GLDN

331

Q6ZMI3
IVDTFWQTETGGHML

ACSS2

461

Q9NR19
HWLSDTFEINRMGSV

DNAI3

486

Q8IWG1
MLLFRSATGEAWHEI

CACNA1B

1646

Q00975
ETEMGGISTTYWHRL

PKD1L1-AS1

86

Q9H7B7
NERHGQSFVDSSSMW

CHD7

131

Q9P2D1
HLDWMSREDGSHILT

DMXL1

1141

Q9Y485
GSVRMFEWGHSQQIT

DMXL1

2766

Q9Y485
VSAEAVWDHVTMANR

ARHGEF9

11

O43307
IFLVIETHGMAVSWD

MUC5B

991

Q9HC84
QMWDTAGQERFRSVT

RAB26

116

Q9ULW5
VEFSHLQDATRWMEA

RBM10

176

P98175
EDIETVTASQMRWTH

HSPG2

36

P98160
LWDTAGQERYHSMTR

RAB44

886

Q7Z6P3
WSCFGTRVIRDMTLH

RFX4

431

Q33E94
VWDSFTTNKEHAVTM

GNB5

131

O14775
ELHGMTSERQFWTVS

INTS8

531

Q75QN2
HAVAASAGMWTLVIV

GPR141

131

Q7Z602
HTGWQAALVSTIIMV

ORAI2

191

Q96SN7
VYHSNRSEWEEVSPM

KBTBD3

571

Q8NAB2
HSRASVMWNRTQVVG

RNF144B

246

Q7Z419
TTLLGFDHMTWQRGN

ANKRD13B

166

Q86YJ7
DQAHAERWAMTSETS

ANO7

31

Q6IWH7
DRATWMALYHNISGV

AOC2

216

O75106
RHLGDNTFWTDTLAM

ANKRD53

486

Q8N9V6
VSWSADHRVIDGATM

DBT

446

P11182
AWGTQVHVIREVASM

BCKDHB

276

P21953
VSLQASSGHMWGTFR

POLDIP2

321

Q9Y2S7
GQELDRVVAFWMEHS

RENBP

26

P51606
LGFLWATVHTTRMSV

OR8D2

151

Q9GZM6
MNFGDWHLFRSTVLE

KIDINS220

1261

Q9ULH0
GHSHGTFEWVDSMLV

MDN1

2216

Q9NU22
HGALRSIFSQMAQWD

GPN2

121

Q9H9Y4
APFHADRVMWSVVSQ

NMUR1

311

Q9HB89
EMNVVRFTGSSWIKH

NELL2

776

Q99435
FLRWSSGETATMHIL

INTS1

1151

Q8N201
ALVHTLDGWSVVQTM

GTPBP6

126

O43824
QTESHRVAGEDMLVW

LEMD2

476

Q8NC56
ELLWSHTFQSGDEMT

HSP90AB4P

361

Q58FF6
RLWVSVEDAQMHTVT

RBCK1

56

Q9BYM8
LIDQVNDTSDGRHMW

KATNIP

1461

O60303
RAWMDGSHRDIFVTS

LRP1

681

Q07954
EWIEMALGASAVVHT

HERC1

266

Q15751
NHTLAVSADGSMVWA

HERC1

4196

Q15751
HKNLDTVRAVWTMGD

KATNB1

506

Q9BVA0
GITMTVAHELAHQWF

ERAP1

346

Q9NZ08
SLPTMTVSDWYEQHR

IGBP1

261

P78318
DLRRWASFMDAGVEH

MSTO1

531

Q9BUK6
EGRQHRSTWSPTMVV

NLRP1

771

Q9C000
VRSRTHVHWMSESGI

GANC

316

Q8TET4
IHEVRIGWSLTTSGM

HNRNPU

356

Q00839
NTMIGTWEDIAFHIS

DNAH12

831

Q6ZR08
VWRAFENPHTSTMAL

KCND2

171

Q9NZV8
AMENYGIEWHSVRDS

MYLIP

181

Q8WY64
VMDILVFHSSRQSGW

LRP6

876

O75581
MRVWLGLSQHSVDQS

LY75

1596

O60449
GAMLYHSWVSEITEI

HEYL

311

Q9NQ87
VARQHIEMSTTGWVG

DPP4

341

P27487
SWHFAGELQRALSAM

GOLGA6L7

131

A0A1B0GV03
TERAMGLSEEWTVHS

HEG1

236

Q9ULI3
MTSRRWFHPNITGVE

PTPN11

1

Q06124
ETSADEMTFREGHQW

ERMN

101

Q8TAM6
ATDGLWETMHRQDVV

PDP1

416

Q9P0J1
MNRVNSIHVESGAWV

CRYGN

36

Q8WXF5
FHSGSSVTRMLWEQI

DSTYK

531

Q6XUX3
DSFWRHTGYVMAQID

PLBD1

156

Q6P4A8
MEVQLSHADVDGSWT

OBSCN

2096

Q5VST9
HIDMDTREWSDGVLT

DYNC2H1

2021

Q8NCM8
QEGHIWGSMRRTAFI

FAXDC2

16

Q96IV6
LRFMDSAQVAHWLDG

EPB41L5

86

Q9HCM4
MSAVVIHNDTVLWTG

LACTBL1

41

A8MY62
DNVSWRHPTMGSVFI

CASP1

336

P29466
KIMHQSSGWERVFGT

DOCK6

1736

Q96HP0
SKIVHQSTGWERMFG

DOCK7

1826

Q96N67
MARHVLDNSGEWSVT

DCAKD

171

Q8WVC6
VSEMHRLSSALWGED

FRMPD2

516

Q68DX3
THWSMGTAARIIAVA

FRRS1

481

Q6ZNA5
VVIVFHNEGWSTLMR

GALNT7

211

Q86SF2
HNEGWSTLMRTVHSV

GALNT7

216

Q86SF2
HGMWQTISVEELARN

GAS6

376

Q14393
HFRGRVSIWAMVTSV

CPAMD8

311

Q8IZJ3
FEAHWTRSGENRTTM

TMEM63B

501

Q5T3F8
TTNTWVLHMDGENFR

FAIM

96

Q9NVQ4
TAGHAATMIAIVWAI

HTR1D

151

P28221
HWSVQRLFTGMQTLE

CERKL

236

Q49MI3
SWEFNEVTSMSEHLK

FBXO40

651

Q9UH90
HGDIFMNRTENWIGS

HEPHL1

766

Q6MZM0
MTRTGWHATEQYLIE

DMGDH

151

Q9UI17
LSHWEMSRAQESVGF

MAPKBP1

826

O60336
WTLVASVHENDMRGK

ITLN2

91

Q8WWU7
FDSQWHKIMIGVERS

COL9A1

176

P20849
TAGWHNITVLAMEAD

CDH22

461

Q9UJ99
ADTTVQSDMKHWPFR

HSPA6

81

P17066
QSDMKHWPFRVVSEG

HSPA6

86

P17066
IWNELHSSGAARMAV

HDAC9

741

Q9UKV0
ILRNHSGDVMDVAWS

HIRA

126

P54198
GNSWHFSRTMEELVH

GPATCH2

16

Q9NW75
TRRHEDGEFWMSFSD

CAPN2

316

P17655
RLQHQVTEDGEFWMS

CAPN3

386

P20807
MSAHNRGTELDLSWI

DERA

1

Q9Y315
VMVAINTWGVSLFHL

SLC13A4

596

Q9UKG4
QEMFSGTRAIQHWLT

POLRMT

1041

O00411
ESARLISHMGSVVEW

POLRMT

1056

O00411
VFALWESGDMSDQHR

POLR3E

636

Q9NVU0
MWDRILSGREHNFNT

MEP1B

176

Q16820
WRHLAEGSAVSLDMF

CYP4F22

186

Q6NT55
TDFGLAREWHKTTQM

MAP3K11

266

Q16584
LVHDAFRLWMTTEAH

DNAH5

4121

Q8TE73
HGVSGVQDRMSVIWE

DPYSL5

346

Q9BPU6
RMTSGSWTETHAVNA

PTPRK

331

Q15262
MEWRNHSGRVSEFVL

OR6A2

1

O95222
DHSGLISVEEFRAMW

PPEF1

581

O14829
MEQLTRSHWEGFASD

FAM149B1

286

Q96BN6
DHMGTFRSILDQLDW

ORC2

361

Q13416
FVSSRWVPQMADHTE

HMGCLL1

121

Q8TB92
WDEGSMNDVALATHF

FER1L6

326

Q2WGJ9
MEVTHVSQLTWARHG

PVR

56

P15151
LDSHGVDFSRVRMWS

UTP25

506

Q68CQ4
RIHVSTDQGDTWSMA

SORT1

326

Q99523
QTMITFDQGGRWTHL

SORT1

426

Q99523
GLQESSHREWGQEMV

SVOP

516

Q8N4V2
NHSAFWGMTLDEGIR

TINAGL1

161

Q9GZM7
FDTVTKELVSWMRGH

TBC1D31

111

Q96DN5
WMRGHESSVFSISVH

TBC1D31

121

Q96DN5
HDSGIIMQIIDVSWT

TAS2R3

76

Q9NYW6
IAEWATHRFQAMGIT

SLC22A9

221

Q8IVM8
LVMVRHGESTWNQEN

PGAM2

6

P15259
SFMVVPSFSIAEHWR

OR5AU1

36

Q8NGC0
RSEEVHWLHVDMGVS

PTK2

91

Q05397
LVIWVAGFRMTHTVT

FPR1

46

P21462
GALAFDAWLEHTTEM

PNMA3

176

Q9UL41
DRKPVWFQTVMSDGH

PTCHD4

416

Q6ZW05
RSIDLGWSGFISHQM

MEP1A

561

Q16819
VMTVFGHISFRSDWE

SORCS2

621

Q96PQ0
TITSMTRVIEVSHWG

RPN1

226

P04843
MWHVIARDFGQSADI

SIPA1L2

856

Q9P2F8
DIGQDMRVHNSTFLW

SETX

396

Q7Z333
SAGMVLDIVQHWEVF

SLC41A2

176

Q96JW4
HFERAPFMSQERTVW

TENM2

981

Q9NT68
QGLWAQMSVFHREDL

NLRP7

421

Q8WX94
DMAAGHLSEAWSRVT

MYCBP2

4181

O75592
NVSRTDWHMAFTGMS

PRRC1

406

Q96M27
ARSHLRQMGVTEWSV

WIZ

1246

O95785
QWSEEASMVFRNHVE

TDRD7

1031

Q8NHU6
AWGSRASETVMVHQA

SUSD6

241

Q92537
WRVSDDTVMHLATAE

ADPRH

51

P54922
LEETSEETGHWQSMF

CGN

561

Q9P2M7
LVTDNAVYHWSMEGE

CLTC

121

Q00610
LVTETAVYHWSMEGD

CLTCL1

121

P53675
LANHTISRWMADSVG

SLC7A14

161

Q8TBB6
MSVLDLGESWRVYHA

TECTA

481

O75443
TSTWLFETHTMDELR

XIRP2

1276

A4UGR9
WLAVGMESSNVEVLH

TLE1

671

Q04724
GTAIITEEHAAMWTD

XPNPEP1

61

Q9NQW7
TMSLWEFEDSHSRQG

ZC3H12A

16

Q5D1E8
IGSAELSFEHDAWMS

TRAPPC11

306

Q7Z392
SAVEFHSAWAMGMRV

VNN1

246

O95497
HSDGVVRFWRMEFLQ

WDFY3

3236

Q8IZQ1
DNIFLTRMHWSNVGG

ELAC2

106

Q9BQ52
STFWSHGLAEMAGQR

PHLPP2

781

Q6ZVD8
VATHDIEMEAASSWQ

PLCH2

636

O75038
RWFTVQAGLSSSVHM

TECPR1

551

Q7Z6L1
MVEREISTGAHSDWK

ZNF514

61

Q96K75
MLETFGHLVSVGWET

ZNF274

316

Q96GC6
HRSLNVDMEWLYGAS

SELENON

336

Q9NZV5
MHAVTSEWISLTVGV

SORBS1

981

Q9BX66
TLHLSWMVTEGEFDS

TNXB

1896

P22105
SHSMDEVSLSAFGEW

SMOX

211

Q9NWM0
LAGYIDWVSMSHITA

XPO5

231

Q9HAV4
TQMTWGALFRHEILS

XPO5

371

Q9HAV4
FDSENRMWTTVHPGA

RAET1G

151

Q6H3X3
DVIDSLVGHSMWLRS

MYCBPAP

776

Q8TBZ2
HGNLMTERQVSRWFV

NUP188

191

Q5SRE5
RFHSQVRDLLSWMDG

SPTBN4

1946

Q9H254
GHRSWAFSDTEAAMA

WDR6

656

Q9NNW5
IIMHEGSWGISHTRV

PIGN

76

O95427
SSFWEIADHGQIDSM

TCL1B

101

O95988
IIMEGVTSQTSHWSR

TPCN1

651

Q9ULQ1
SHVSWITGQAMEIGS

ZSWIM8

1306

A7E2V4
ETLELFQSVHGWLMV

UBE3B

586

Q7Z3V4
LEDHGLLVTWMNFVS

UBR3

531

Q6ZT12
TTVALHDWATYSEMR

WASHC4

741

Q2M389
QTSLVSDGETWHVMG

PHGDH

496

O43175
TRWLQEFTRHHGTMS

PIEZO1

1526

Q92508
ALWQMDVTHVSSFGR

ERVK-19

651

Q9WJR5
AMFEEHRDVTTGIAW

WDR24

291

Q96S15
VFRSLLTDHMDFWGR

UGT3A2

186

Q3SY77
METVSEAGTHQEWSF

ZNF224

86

Q9NZL3
VRWEVQSGESNQMVH

SEMA6D

646

Q8NFY4
GDIQWRSFHLEASLM

TRPM4

416

Q8TD43
ESDGSQCQHWVRLTM

HECTD3

271

Q5T447
EWFHVAPMNTRRSSV

KLHL2

426

O95198
EKTVASWQHMATEAA

LAMC3

1276

Q9Y6N6
LVVGTHSWRDQFMEA

SLC8A3

691

P57103
HSWRDQFMEAITVSA

SLC8A3

696

P57103