Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR10G6 LHCGR OR6B1 VIPR2 ADORA3 IL13RA2 OR4N2 OR4N4 TAS2R36 GPR149 SCARB2 MRGPRF FSHR HTR3E OR2V1 LMBR1 OR1C1 OR8B12 ADGRA1 OR8U3 FGFR1 RXFP1 LTB4R2 TAS2R30 ADGRE2 GRM6 GRM7 IL22RA1 OR14A16 OR8U9	3.99e-14	1353	88	30	GO:0004888
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR10G6 LHCGR OR6B1 VIPR2 ADORA3 OR4N2 OR4N4 TAS2R36 GPR149 MRGPRF FSHR OR2V1 OR1C1 OR8B12 ADGRA1 OR8U3 RXFP1 LTB4R2 TAS2R30 ADGRE2 GRM6 GRM7 OR14A16 OR8U9	3.75e-13	884	88	24	GO:0004930
GeneOntologyMolecularFunction	olfactory receptor activity	OR10G6 OR6B1 OR4N2 OR4N4 OR2V1 OR1C1 OR8B12 OR8U3 OR14A16 OR8U9	1.99e-05	431	88	10	GO:0004984
GeneOntologyMolecularFunction	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	CSGALNACT2 CSGALNACT1	5.74e-05	3	88	2	GO:0047237
GeneOntologyMolecularFunction	group III metabotropic glutamate receptor activity	GRM6 GRM7	1.15e-04	4	88	2	GO:0001642
GeneOntologyMolecularFunction	transmembrane ascorbate ferrireductase activity	CYB561D1 CYB561A3	1.15e-04	4	88	2	GO:0140571
GeneOntologyMolecularFunction	protein-cysteine S-palmitoyltransferase activity	ZDHHC11B ZDHHC19 ZDHHC11	2.00e-04	26	88	3	GO:0019706
GeneOntologyMolecularFunction	protein-cysteine S-acyltransferase activity	ZDHHC11B ZDHHC19 ZDHHC11	2.00e-04	26	88	3	GO:0019707
GeneOntologyMolecularFunction	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	CSGALNACT2 CSGALNACT1	2.85e-04	6	88	2	GO:0047238
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	LHCGR VIPR2 FSHR RXFP1 LTB4R2	3.06e-04	133	88	5	GO:0008528
GeneOntologyMolecularFunction	S-acyltransferase activity	ZDHHC11B ZDHHC19 ZDHHC11	3.08e-04	30	88	3	GO:0016417
GeneOntologyMolecularFunction	peptide receptor activity	LHCGR VIPR2 FSHR RXFP1 LTB4R2	3.87e-04	140	88	5	GO:0001653
GeneOntologyMolecularFunction	palmitoyltransferase activity	ZDHHC11B ZDHHC19 ZDHHC11	5.77e-04	37	88	3	GO:0016409
GeneOntologyMolecularFunction	G protein-coupled glutamate receptor activity	GRM6 GRM7	6.78e-04	9	88	2	GO:0098988
GeneOntologyMolecularFunction	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity	GRM6 GRM7	6.78e-04	9	88	2	GO:0001640
GeneOntologyMolecularFunction	hormone binding	LHCGR VIPR2 FSHR RXFP1	1.12e-03	103	88	4	GO:0042562
GeneOntologyMolecularFunction	ATP transmembrane transporter activity	SLC17A9 ANKH	1.69e-03	14	88	2	GO:0005347
GeneOntologyMolecularFunction	peptide hormone binding	LHCGR VIPR2 FSHR	1.84e-03	55	88	3	GO:0017046
GeneOntologyMolecularFunction	carbohydrate derivative transmembrane transporter activity	SLC17A9 SLC35D2 ANKH	2.25e-03	59	88	3	GO:1901505
GeneOntologyMolecularFunction	nucleobase-containing compound transmembrane transporter activity	SLC17A9 SLC35D2 ANKH	2.25e-03	59	88	3	GO:0015932
GeneOntologyMolecularFunction	odorant binding	OR8B12 OR8U3 OR14A16 OR8U9	2.41e-03	127	88	4	GO:0005549
GeneOntologyMolecularFunction	hexosyltransferase activity	CSGALNACT2 FUT9 ALG8 B3GALT5 CSGALNACT1	2.42e-03	211	88	5	GO:0016758
GeneOntologyMolecularFunction	oxidoreductase activity, acting on metal ions	CYB561D1 CYB561A3	2.81e-03	18	88	2	GO:0016722
GeneOntologyMolecularFunction	transporter activity	SLC17A9 SLC35D2 GSDMD NPC1L1 HTR3E CYB561D1 SLC35F2 SLC12A8 SLC49A3 KCNK13 CYB561A3 GRM7 ANKH	4.13e-03	1289	88	13	GO:0005215
GeneOntologyMolecularFunction	protein-hormone receptor activity	LHCGR FSHR	4.19e-03	22	88	2	GO:0016500
GeneOntologyMolecularFunction	purine ribonucleotide transmembrane transporter activity	SLC17A9 ANKH	4.57e-03	23	88	2	GO:0005346
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR10G6 LHCGR OR6B1 VIPR2 ADORA3 OR4N2 OR4N4 TAS2R36 GPR149 MRGPRF FSHR OR2V1 OR1C1 OR8B12 ADGRA1 OR8U3 RXFP1 LTB4R2 TAS2R30 ADGRE2 GRM6 GRM7 OR14A16 HTT OR8U9	3.36e-10	1395	87	25	GO:0007186
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR10G6 OR6B1 OR4N2 OR4N4 TAS2R36 OR2V1 OR1C1 OR8B12 OR8U3 TAS2R30 OR14A16 OR8U9	8.95e-07	485	87	12	GO:0050907
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR10G6 OR6B1 OR4N2 OR4N4 TAS2R36 OR2V1 OR1C1 OR8B12 OR8U3 TAS2R30 GRM6 OR14A16 OR8U9	9.51e-07	582	87	13	GO:0050906
GeneOntologyBiologicalProcess	detection of stimulus	OR10G6 OR6B1 OR4N2 OR4N4 TAS2R36 OR2V1 OR1C1 OR8B12 TIMELESS OR8U3 TAS2R30 GRM6 OR14A16 OR8U9	1.86e-06	722	87	14	GO:0051606
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR10G6 OR6B1 OR4N2 OR4N4 TAS2R36 OR2V1 OR1C1 OR8B12 OR8U3 TAS2R30 OR14A16 OR8U9	2.00e-06	524	87	12	GO:0009593
GeneOntologyBiologicalProcess	lipoprotein metabolic process	RAB3GAP1 ZDHHC11B PIGC NPC1L1 ZDHHC19 ATM ZDHHC11	2.94e-06	147	87	7	GO:0042157
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR10G6 OR6B1 OR4N2 OR4N4 TAS2R36 OR2V1 OR1C1 OR8B12 OR8U3 TAS2R30 OR14A16 OR8U9	3.12e-06	547	87	12	GO:0007606
GeneOntologyBiologicalProcess	dermatan sulfate proteoglycan biosynthetic process	CSGALNACT2 UST CSGALNACT1	4.00e-06	8	87	3	GO:0050651
GeneOntologyBiologicalProcess	regulation of adenylate cyclase activity	LHCGR ADORA3 FSHR RXFP1 LTB4R2	4.97e-06	59	87	5	GO:0045761
GeneOntologyBiologicalProcess	sensory perception	OR10G6 OR6B1 OR4N2 OR4N4 TAS2R36 SCARB2 OR2V1 OR1C1 OR8B12 OR8U3 FGFR1 TAS2R30 GRM6 GRM7 OR14A16 OR8U9	9.21e-06	1072	87	16	GO:0007600
GeneOntologyBiologicalProcess	regulation of cyclase activity	LHCGR ADORA3 FSHR RXFP1 LTB4R2	1.08e-05	69	87	5	GO:0031279
GeneOntologyBiologicalProcess	activation of adenylate cyclase activity	LHCGR ADORA3 FSHR RXFP1	1.24e-05	34	87	4	GO:0007190
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR10G6 OR6B1 OR4N2 OR4N4 OR2V1 OR1C1 OR8B12 OR8U3 OR14A16 OR8U9	1.39e-05	432	87	10	GO:0050911
GeneOntologyBiologicalProcess	regulation of lyase activity	LHCGR ADORA3 FSHR RXFP1 LTB4R2	1.42e-05	73	87	5	GO:0051339
GeneOntologyBiologicalProcess	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	CSGALNACT2 CSGALNACT1	1.76e-05	2	87	2	GO:0050653
GeneOntologyBiologicalProcess	dermatan sulfate proteoglycan metabolic process	CSGALNACT2 UST CSGALNACT1	2.01e-05	13	87	3	GO:0050655
GeneOntologyBiologicalProcess	positive regulation of adenylate cyclase activity	LHCGR ADORA3 FSHR RXFP1	2.40e-05	40	87	4	GO:0045762
GeneOntologyBiologicalProcess	sensory perception of smell	OR10G6 OR6B1 OR4N2 OR4N4 OR2V1 OR1C1 OR8B12 OR8U3 OR14A16 OR8U9	2.61e-05	465	87	10	GO:0007608
GeneOntologyBiologicalProcess	positive regulation of cyclase activity	LHCGR ADORA3 FSHR RXFP1	4.99e-05	48	87	4	GO:0031281
GeneOntologyBiologicalProcess	positive regulation of lyase activity	LHCGR ADORA3 FSHR RXFP1	5.41e-05	49	87	4	GO:0051349
GeneOntologyBiologicalProcess	proteoglycan metabolic process	CSGALNACT2 SLC35D2 SULF1 UST CSGALNACT1	5.65e-05	97	87	5	GO:0006029
GeneOntologyBiologicalProcess	protein lipidation	RAB3GAP1 ZDHHC11B PIGC ZDHHC19 ZDHHC11	6.85e-05	101	87	5	GO:0006497
GeneOntologyBiologicalProcess	lipoprotein biosynthetic process	RAB3GAP1 ZDHHC11B PIGC ZDHHC19 ZDHHC11	8.62e-05	106	87	5	GO:0042158
GeneOntologyBiologicalProcess	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine	ZDHHC11B ZDHHC19 ZDHHC11	1.38e-04	24	87	3	GO:0018231
GeneOntologyBiologicalProcess	peptidyl-L-cysteine S-palmitoylation	ZDHHC11B ZDHHC19 ZDHHC11	1.38e-04	24	87	3	GO:0018230
GeneOntologyBiologicalProcess	diphosphate metabolic process	FGFR1 ANKH	1.74e-04	5	87	2	GO:0071344
GeneOntologyBiologicalProcess	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	LHCGR VIPR2 FSHR RXFP1 ADGRE2 GRM6 GRM7	2.08e-04	286	87	7	GO:0007188
GeneOntologyBiologicalProcess	proteoglycan biosynthetic process	CSGALNACT2 SLC35D2 UST CSGALNACT1	2.19e-04	70	87	4	GO:0030166
GeneOntologyBiologicalProcess	synaptic transmission, glutamatergic	RAB3GAP1 CNIH2 GRM6 GRM7 CNIH3	2.42e-04	132	87	5	GO:0035249
GeneOntologyBiologicalProcess	positive regulation of aggrephagy	ZDHHC19 HTT	2.61e-04	6	87	2	GO:1905337
GeneOntologyBiologicalProcess	glycosaminoglycan biosynthetic process	CSGALNACT2 SLC35D2 UST CSGALNACT1	3.01e-04	76	87	4	GO:0006024
GeneOntologyBiologicalProcess	protein palmitoylation	ZDHHC11B ZDHHC19 ZDHHC11	3.61e-04	33	87	3	GO:0018345
GeneOntologyBiologicalProcess	ATP export	SLC17A9 ANKH	3.64e-04	7	87	2	GO:1904669
GeneOntologyBiologicalProcess	cementum mineralization	FGFR1 ANKH	3.64e-04	7	87	2	GO:0071529
GeneOntologyBiologicalProcess	aminoglycan biosynthetic process	CSGALNACT2 SLC35D2 UST CSGALNACT1	3.66e-04	80	87	4	GO:0006023
GeneOntologyBiologicalProcess	glycoprotein metabolic process	CSGALNACT2 SLC35D2 SULF1 FUT9 ALG8 B3GALT5 UST CSGALNACT1	4.64e-04	430	87	8	GO:0009100
GeneOntologyBiologicalProcess	regulation of aggrephagy	ZDHHC19 HTT	4.84e-04	8	87	2	GO:1905335
GeneOntologyBiologicalProcess	ovarian follicle development	LHCGR GPR149 FSHR ATM	5.03e-04	87	87	4	GO:0001541
GeneOntologyBiologicalProcess	adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway	GRM6 GRM7	6.21e-04	9	87	2	GO:0007196
GeneOntologyBiologicalProcess	regulation of mast cell degranulation	ADORA3 IL13RA2 ADGRE2	7.39e-04	42	87	3	GO:0043304
GeneOntologyBiologicalProcess	glycoprotein biosynthetic process	CSGALNACT2 SLC35D2 FUT9 ALG8 B3GALT5 UST CSGALNACT1	7.83e-04	357	87	7	GO:0009101
GeneOntologyBiologicalProcess	mucopolysaccharide metabolic process	CSGALNACT2 SLC35D2 UST CSGALNACT1	8.51e-04	100	87	4	GO:1903510
GeneOntologyBiologicalProcess	regulation of protein localization to nucleolus	POLR1A TERT	9.44e-04	11	87	2	GO:1904749
GeneOntologyCellularComponent	Golgi membrane	TLCD3B CSGALNACT2 SLC35D2 SCARB2 CNIH1 FUT9 B3GALT5 ZDHHC19 TVP23B GRM6 ZDHHC11 UST CSGALNACT1	1.10e-05	721	89	13	GO:0000139
MousePheno	abnormal estrus	LHCGR GPR149 FSHR ATM	1.78e-05	34	65	4	MP:0009016
Domain	G_PROTEIN_RECEP_F1_1	OR10G6 LHCGR OR6B1 ADORA3 OR4N2 OR4N4 GPR149 MRGPRF FSHR OR2V1 OR1C1 OR8B12 OR8U3 RXFP1 LTB4R2 OR14A16 OR8U9	6.86e-09	685	83	17	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR10G6 LHCGR OR6B1 ADORA3 OR4N2 OR4N4 GPR149 MRGPRF FSHR OR2V1 OR1C1 OR8B12 OR8U3 RXFP1 LTB4R2 OR14A16 OR8U9	7.81e-09	691	83	17	PS50262
Domain	GPCR_Rhodpsn	OR10G6 LHCGR OR6B1 ADORA3 OR4N2 OR4N4 GPR149 MRGPRF FSHR OR2V1 OR1C1 OR8B12 OR8U3 RXFP1 LTB4R2 OR14A16 OR8U9	7.97e-09	692	83	17	IPR000276
Domain	GPCR_Rhodpsn_7TM	LHCGR OR6B1 ADORA3 OR4N2 OR4N4 GPR149 MRGPRF FSHR OR2V1 OR1C1 OR8B12 OR8U3 RXFP1 LTB4R2 OR14A16 OR8U9	3.47e-08	670	83	16	IPR017452
Domain	7tm_1	OR10G6 LHCGR OR6B1 ADORA3 OR4N2 OR4N4 GPR149 MRGPRF FSHR OR1C1 OR8B12 OR8U3 RXFP1 LTB4R2 OR14A16 OR8U9	4.01e-08	677	83	16	PF00001
Domain	Cornichon_conserved	CNIH2 CNIH1 CNIH3	8.46e-08	3	83	3	IPR033466
Domain	CORNICHON	CNIH2 CNIH1 CNIH3	8.46e-08	3	83	3	PS01340
Domain	Cornichon	CNIH2 CNIH1 CNIH3	3.37e-07	4	83	3	PF03311
Domain	Cornichon	CNIH2 CNIH1 CNIH3	3.37e-07	4	83	3	IPR003377
Domain	Cornichon	CNIH2 CNIH1 CNIH3	3.37e-07	4	83	3	SM01398
Domain	Olfact_rcpt	OR10G6 OR6B1 OR4N2 OR4N4 OR2V1 OR1C1 OR8B12 OR8U3 OR14A16 OR8U9	9.41e-06	393	83	10	IPR000725
Domain	Cytochrom_B561	CYB561D1 CYB561A3	1.93e-04	5	83	2	PF03188
Domain	CYTOCHROME_B561	CYB561D1 CYB561A3	2.89e-04	6	83	2	PS50939
Domain	B561	CYB561D1 CYB561A3	2.89e-04	6	83	2	SM00665
Domain	Cyt_b561/ferric_Rdtase_TM	CYB561D1 CYB561A3	2.89e-04	6	83	2	IPR006593
Domain	Gphrmn_rcpt_fam	LHCGR FSHR	2.89e-04	6	83	2	IPR002131
Domain	GPCR_2_secretin-like_CS	VIPR2 ADGRA1 ADGRE2	4.58e-04	34	83	3	IPR017983
Domain	Chond_GalNAc	CSGALNACT2 CSGALNACT1	5.37e-04	8	83	2	IPR008428
Domain	GPCR_3_mtglu_rcpt	GRM6 GRM7	5.37e-04	8	83	2	IPR000162
Domain	CHGN	CSGALNACT2 CSGALNACT1	5.37e-04	8	83	2	PF05679
Domain	LDLR_class-A_CS	LRP12 CORIN RXFP1	7.43e-04	40	83	3	IPR023415
Domain	LRR_5	LHCGR FSHR	8.58e-04	10	83	2	PF13306
Domain	LRR_5	LHCGR FSHR	8.58e-04	10	83	2	IPR026906
Domain	Ldl_recept_a	LRP12 CORIN RXFP1	1.05e-03	45	83	3	PF00057
Domain	-	LRP12 CORIN RXFP1	1.12e-03	46	83	3	4.10.400.10
Domain	LDLRA_1	LRP12 CORIN RXFP1	1.27e-03	48	83	3	PS01209
Domain	LDLRA_2	LRP12 CORIN RXFP1	1.35e-03	49	83	3	PS50068
Domain	LDrepeatLR_classA_rpt	LRP12 CORIN RXFP1	1.35e-03	49	83	3	IPR002172
Domain	LDLa	LRP12 CORIN RXFP1	1.35e-03	49	83	3	SM00192
Domain	G_PROTEIN_RECEP_F2_2	VIPR2 ADGRA1 ADGRE2	1.43e-03	50	83	3	PS00650
Domain	7tm_2	VIPR2 ADGRA1 ADGRE2	1.43e-03	50	83	3	PF00002
Domain	NCD3G	GRM6 GRM7	1.47e-03	13	83	2	PF07562
Domain	GPCR_3_9-Cys_dom	GRM6 GRM7	1.47e-03	13	83	2	IPR011500
Domain	GPCR_3_CS	GRM6 GRM7	1.72e-03	14	83	2	IPR017979
Domain	GPCR_2_secretin-like	VIPR2 ADGRA1 ADGRE2	2.41e-03	60	83	3	IPR000832
Domain	GPCR_2-like	VIPR2 ADGRA1 ADGRE2	2.41e-03	60	83	3	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	VIPR2 ADGRA1 ADGRE2	2.53e-03	61	83	3	PS50261
Domain	GPCR_3	GRM6 GRM7	3.88e-03	21	83	2	IPR000337
Domain	7tm_3	GRM6 GRM7	4.25e-03	22	83	2	PF00003
Domain	G_PROTEIN_RECEP_F3_2	GRM6 GRM7	4.25e-03	22	83	2	PS00980
Domain	G_PROTEIN_RECEP_F3_3	GRM6 GRM7	4.25e-03	22	83	2	PS00981
Domain	G_PROTEIN_RECEP_F3_1	GRM6 GRM7	4.25e-03	22	83	2	PS00979
Domain	G_PROTEIN_RECEP_F3_4	GRM6 GRM7	4.25e-03	22	83	2	PS50259
Domain	GPCR_3_C	GRM6 GRM7	4.25e-03	22	83	2	IPR017978
Domain	zf-DHHC	ZDHHC19 ZDHHC11	4.65e-03	23	83	2	PF01529
Domain	DHHC	ZDHHC19 ZDHHC11	5.48e-03	25	83	2	PS50216
Domain	Znf_DHHC_palmitoyltrfase	ZDHHC19 ZDHHC11	5.48e-03	25	83	2	IPR001594
Pathway	WP_GPCRS_NONODORANT	LHCGR VIPR2 ADORA3 FSHR RXFP1 LTB4R2 ADGRE2 GRM6 GRM7	4.35e-06	266	67	9	MM15843
Pathway	REACTOME_GPCR_LIGAND_BINDING	LHCGR VIPR2 ADORA3 UTS2 FSHR RXFP1 LTB4R2 TAS2R30 ADGRE2 GRM6 GRM7	5.16e-06	430	67	11	MM15160
Pathway	REACTOME_GPCR_LIGAND_BINDING	LHCGR VIPR2 ADORA3 UTS2 FSHR RXFP1 LTB4R2 TAS2R30 ADGRE2 GRM6 GRM7	1.04e-05	463	67	11	M507
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR10G6 OR6B1 OR4N2 OR4N4 OR2V1 OR1C1 OR8B12 OR8U3 OR14A16 OR8U9	2.53e-05	417	67	10	M4072
Pathway	REACTOME_SENSORY_PERCEPTION	OR10G6 OR6B1 LRP12 OR4N2 OR4N4 OR2V1 OR1C1 OR8B12 OR8U3 TAS2R30 OR14A16 OR8U9	3.94e-05	636	67	12	M41834
Pathway	KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	LHCGR VIPR2 ADORA3 FSHR RXFP1 LTB4R2 GRM6 GRM7	4.22e-05	272	67	8	M13380
Pathway	WP_GPCRS_OTHER	ADORA3 FSHR RXFP1 LTB4R2 ADGRE2	7.84e-05	93	67	5	M39629
Pathway	KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE	CSGALNACT2 UST CSGALNACT1	1.48e-04	22	67	3	M19166
Pathway	REACTOME_SIGNALING_BY_GPCR	LHCGR VIPR2 ADORA3 UTS2 FSHR RXFP1 LTB4R2 TAS2R30 ADGRE2 GRM6 GRM7	2.12e-04	646	67	11	MM14962
Pathway	REACTOME_COPII_MEDIATED_VESICLE_TRANSPORT	CNIH2 CNIH1 SEC22A CNIH3	3.19e-04	69	67	4	M27113
Pathway	REACTOME_SIGNALING_BY_GPCR	LHCGR VIPR2 ADORA3 UTS2 FSHR RXFP1 LTB4R2 TAS2R30 ADGRE2 GRM6 GRM7	4.33e-04	702	67	11	M746
Pathway	REACTOME_CARGO_CONCENTRATION_IN_THE_ER	CNIH2 CNIH1 CNIH3	5.06e-04	33	67	3	M27591
Pathway	WP_OVARIAN_INFERTILITY	LHCGR FSHR ATM	6.02e-04	35	67	3	MM15948
Pathway	KEGG_MEDICUS_REFERENCE_CHONDROITIN_SULFATE_BIOSYNTHESIS	CSGALNACT2 CSGALNACT1	6.12e-04	8	67	2	M47920
Pathway	REACTOME_COPII_MEDIATED_VESICLE_TRANSPORT	CNIH2 CNIH1 SEC22A CNIH3	6.46e-04	83	67	4	MM14819
Pathway	REACTOME_CARGO_CONCENTRATION_IN_THE_ER	CNIH2 CNIH1 CNIH3	6.55e-04	36	67	3	MM15300
Pathway	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	TAS2R30 GRM6 GRM7	7.10e-04	37	67	3	MM15067
Pathway	WP_OVARIAN_INFERTILITY	LHCGR FSHR ATM	8.30e-04	39	67	3	M39458
Pathway	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	TAS2R30 GRM6 GRM7	8.30e-04	39	67	3	M793
Pathway	WP_GLYCOSAMINOGLYCAN_SYNTHESIS_IN_FIBROBLASTS	CSGALNACT2 UST CSGALNACT1	9.61e-04	41	67	3	M48095
Pathway	REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS	LHCGR FSHR	1.42e-03	12	67	2	M13070
Pathway	REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM	CSGALNACT2 UST CSGALNACT1	1.52e-03	48	67	3	MM14696
Pathway	REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM	CSGALNACT2 UST CSGALNACT1	1.71e-03	50	67	3	M678
Pathway	REACTOME_METABOLISM_OF_CARBOHYDRATES	CSGALNACT2 SLC35D2 FUT9 B3GALT5 UST CSGALNACT1	1.79e-03	271	67	6	MM15406
Pathway	KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GLOBO_SERIES	FUT9 B3GALT5	1.95e-03	14	67	2	M12899
Pathway	WP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE	GRM6 GRM7	2.25e-03	15	67	2	M39442
Pathway	WP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE	GRM6 GRM7	2.25e-03	15	67	2	MM15845
Pathway	REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CELL_DEATH_GENES	TMEM219 ATM	2.25e-03	15	67	2	MM15227
Pathway	REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS	LHCGR FSHR	2.25e-03	15	67	2	MM14972
Pubmed	ZDHHC19 localizes to the cell membrane of spermatids and is involved in spermatogenesis†.	ZDHHC11B ZDHHC19 ZDHHC11	1.68e-08	3	90	3	34897408
Pubmed	Upregulation of cornichon transcripts in the dorsolateral prefrontal cortex in schizophrenia.	CNIH2 CNIH1 CNIH3	1.68e-08	3	90	3	23103966
Pubmed	Systematic identification of pathological lamin A interactors.	CSGALNACT2 SCARB2 LMBR1 ALG8 KCNK13 ADGRE2 SEC22A CNIH3 VSTM1	2.40e-07	337	90	9	24623722
Pubmed	The G protein-coupled receptor repertoires of human and mouse.	GPR149 ADGRA1 RXFP1 GRM6 GRM7	2.01e-06	79	90	5	12679517
Pubmed	Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons.	OR2V1 OR1C1 OR14A16 OR4N4C	6.30e-06	46	90	4	32126975
Pubmed	Mechanisms of gonadotropin desensitization.	LHCGR FSHR	6.62e-06	2	90	2	11988313
Pubmed	ZDHHC11 and ZDHHC11B are critical novel components of the oncogenic MYC-miR-150-MYB network in Burkitt lymphoma.	ZDHHC11B ZDHHC11	6.62e-06	2	90	2	28331227
Pubmed	Evidence for chromosome 2p16.3 polycystic ovary syndrome susceptibility locus in affected women of European ancestry.	LHCGR FSHR	6.62e-06	2	90	2	23118426
Pubmed	Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer.	ATM TERT	6.62e-06	2	90	2	22341440
Pubmed	Analysis of pituitary gonadotropin concentration in blood serum and immunolocalization and immunoexpression of follicle stimulating hormone and luteinising hormone receptors in ovaries of postmenopausal women.	LHCGR FSHR	6.62e-06	2	90	2	22207559
Pubmed	Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease.	ATM HTT	6.62e-06	2	90	2	25540325
Pubmed	Association of human follitropin (FSH) receptor with splicing variant of human lutropin/choriogonadotropin receptor negatively controls the expression of human FSH receptor.	LHCGR FSHR	6.62e-06	2	90	2	15890674
Pubmed	Telomerase reverse transcriptase protects ATM-deficient hematopoietic stem cells from ROS-induced apoptosis through a telomere-independent mechanism.	ATM TERT	6.62e-06	2	90	2	21297001
Pubmed	The effect of splice variant of the human luteinizing hormone (LH) receptor on the expression of gonadotropin receptor.	LHCGR FSHR	6.62e-06	2	90	2	17092637
Pubmed	The Luteinizing Hormone Receptor Knockout Mouse as a Tool to Probe the In Vivo Actions of Gonadotropic Hormones/Receptors in Females.	LHCGR FSHR	6.62e-06	2	90	2	33605422
Pubmed	Associations of FSHR and LHCGR gene variants with ovarian reserve and clinical pregnancy rates.	LHCGR FSHR	6.62e-06	2	90	2	34391684
Pubmed	Alterations of the FSH and LH receptor genes and evaluation of sperm ultrastructure in men with idiopathic hypergonadotropic hypogonadism.	LHCGR FSHR	6.62e-06	2	90	2	23884663
Pubmed	AMPA receptor modulation by cornichon-2 dictated by transmembrane AMPA receptor regulatory protein isoform.	CNIH2 CNIH1	6.62e-06	2	90	2	22211840
Pubmed	Alterations in the chondroitin sulfate chain in human osteoarthritic cartilage of the knee.	CSGALNACT2 CSGALNACT1	6.62e-06	2	90	2	24280246
Pubmed	Reduced Gonadotrophin Receptor Expression Is Associated with a More Aggressive Ovarian Cancer Phenotype.	LHCGR FSHR	6.62e-06	2	90	2	33374698
Pubmed	Leutinizing hormone/choriogonadotropin receptor and follicle stimulating hormone receptor gene variants in polycystic ovary syndrome.	LHCGR FSHR	6.62e-06	2	90	2	25649397
Pubmed	Identification of novel splice variants of Adhesion G protein-coupled receptors.	ADGRA1 ADGRE2	6.62e-06	2	90	2	17056209
Pubmed	Stress-induced premature senescence in hTERT-expressing ataxia telangiectasia fibroblasts.	ATM TERT	6.62e-06	2	90	2	14570874
Pubmed	Constitutively active follicle-stimulating hormone receptor enables androgen-independent spermatogenesis.	LHCGR FSHR	6.62e-06	2	90	2	29584617
Pubmed	Intrinsic differences in the response of the human lutropin receptor versus the human follitropin receptor to activating mutations.	LHCGR FSHR	6.62e-06	2	90	2	17609213
Pubmed	Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex.	ATM HTT	6.62e-06	2	90	2	28017939
Pubmed	Molecular cloning and expression of human chondroitin N-acetylgalactosaminyltransferase: the key enzyme for chain initiation and elongation of chondroitin/dermatan sulfate on the protein linkage region tetrasaccharide shared by heparin/heparan sulfate.	CSGALNACT2 CSGALNACT1	6.62e-06	2	90	2	11788602
Pubmed	Differential roles of two N-acetylgalactosaminyltransferases, CSGalNAcT-1, and a novel enzyme, CSGalNAcT-2. Initiation and elongation in synthesis of chondroitin sulfate.	CSGALNACT2 CSGALNACT1	6.62e-06	2	90	2	12446672
Pubmed	The murine luteinizing hormone and follicle-stimulating hormone receptor genes: transcription initiation sites, putative promoter sequences and promoter activity.	LHCGR FSHR	6.62e-06	2	90	2	1459341
Pubmed	The mouse cornichon gene family.	CNIH2 CNIH1	6.62e-06	2	90	2	10022955
Pubmed	Targeting gonadotropin receptor genes: reproductive biology, aging, and related health implications.	LHCGR FSHR	6.62e-06	2	90	2	16034175
Pubmed	Gonadotropin receptor polymorphisms (FSHR N680S and LHCGR N312S) are not predictive of clinical outcome and live birth in assisted reproductive technology.	LHCGR FSHR	6.62e-06	2	90	2	35842313
Pubmed	Heterodimerization between the lutropin and follitropin receptors is associated with an attenuation of hormone-dependent signaling.	LHCGR FSHR	6.62e-06	2	90	2	23825122
Pubmed	Mutations of the Huntington's disease protein impact on the ATM-dependent signaling and repair pathways of the radiation-induced DNA double-strand breaks: corrective effect of statins and bisphosphonates.	ATM HTT	6.62e-06	2	90	2	24277524
Pubmed	Expression of genes encoding for proteins involved in heparan sulphate and chondroitin sulphate chain synthesis and modification in normal and malignant plasma cells.	CSGALNACT2 CSGALNACT1	6.62e-06	2	90	2	19298595
Pubmed	Testis-specific hnRNP is expressed in colorectal cancer cells and accelerates cell growth mediating ZDHHC11 mRNA stabilization.	ZDHHC11B ZDHHC11	6.62e-06	2	90	2	35384384
Pubmed	Infertility and ovarian follicle reserve depletion are associated with dysregulation of the FSH and LH receptor density in human antral follicles.	LHCGR FSHR	6.62e-06	2	90	2	28188844
Pubmed	FSH and LH receptors are differentially expressed in cumulus cells surrounding developmentally competent and incompetent mouse fully grown antral oocytes.	LHCGR FSHR	6.62e-06	2	90	2	24476692
Pubmed	Evidence for expression and functionality of FSH and LH/hCG receptors in human endometrium.	LHCGR FSHR	6.62e-06	2	90	2	29974367
Pubmed	Combined assessment of polymorphisms in the LHCGR and FSHR genes predict chance of pregnancy after in vitro fertilization.	LHCGR FSHR	6.62e-06	2	90	2	26769719
Pubmed	Triptorelin and cetrorelix induce immune responses and affect uterine development and expressions of genes and proteins of ESR1, LHR, and FSHR of mice.	LHCGR FSHR	1.98e-05	3	90	2	27075695
Pubmed	Chondroitin sulphate N-acetylgalactosaminyl-transferase-1 inhibits recovery from neural injury.	CSGALNACT2 CSGALNACT1	1.98e-05	3	90	2	24220492
Pubmed	Aetiological coding sequence variants in non-syndromic premature ovarian failure: From genetic linkage analysis to next generation sequencing.	LHCGR FSHR	1.98e-05	3	90	2	25960166
Pubmed	LH (Trp8Arg/Ile15Thr), LHR (insLQ) and FSHR (Asn680Ser) polymorphisms genotypic prevalence in women with endometriosis and infertility.	LHCGR FSHR	1.98e-05	3	90	2	25935136
Pubmed	Genetic polymorphisms of GnRH and gonadotrophic hormone receptors affect the phenotype of polycystic ovary syndrome.	LHCGR FSHR	1.98e-05	3	90	2	19403562
Pubmed	Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone-receptor interactions.	LHCGR FSHR	1.98e-05	3	90	2	8747461
Pubmed	Regulation of luteinizing hormone-receptor and follicle-stimulating hormone-receptor messenger ribonucleic acid levels during development in the neonatal mouse ovary.	LHCGR FSHR	1.98e-05	3	90	2	9282997
Pubmed	Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors.	LHCGR FSHR	1.98e-05	3	90	2	11847099
Pubmed	Ras homolog enriched in striatum inhibits the functional activity of wild type thyrotropin, follicle-stimulating hormone, luteinizing hormone receptors and activating thyrotropin receptor mutations by altering their expression in COS-7 cells.	LHCGR FSHR	1.98e-05	3	90	2	17556863
Pubmed	Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity.	LHCGR FSHR	1.98e-05	3	90	2	15889138
Pubmed	GlcUAβ1-3Galβ1-3Galβ1-4Xyl(2-O-phosphate) is the preferred substrate for chondroitin N-acetylgalactosaminyltransferase-1.	CSGALNACT2 CSGALNACT1	1.98e-05	3	90	2	25568321
Pubmed	The G-protein coupled estrogen receptor (GPER/GPR30) is a gonadotropin receptor dependent positive prognosticator in ovarian carcinoma patients.	LHCGR FSHR	1.98e-05	3	90	2	23951246
Pubmed	Mammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint control.	TIMELESS ATM	1.98e-05	3	90	2	19996108
Pubmed	Gene Expression in Granulosa Cells From Small Antral Follicles From Women With or Without Polycystic Ovaries.	LHCGR FSHR	1.98e-05	3	90	2	31276164
Pubmed	Expression of mRNA for the LH and FSH receptors in mouse oocytes and preimplantation embryos.	LHCGR FSHR	1.98e-05	3	90	2	11226072
Pubmed	Association of gonadotropin receptor precursors with the protein folding chaperone calnexin.	LHCGR FSHR	1.98e-05	3	90	2	9528938
Pubmed	A genome-wide association study identified a novel genetic loci STON1-GTF2A1L/LHCGR/FSHR for bilaterality of neovascular age-related macular degeneration.	LHCGR FSHR	1.98e-05	3	90	2	28775256
Pubmed	A threshold concentration of FSH is needed during IVM of ex vivo collected human oocytes.	LHCGR FSHR	1.98e-05	3	90	2	34050448
Pubmed	Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus.	LHCGR VIPR2 FSHR RXFP1	3.37e-05	70	90	4	12036966
Pubmed	Influence of mutations affecting gonadotropin production or responsiveness on expression of inhibin subunit mRNA and protein in the mouse ovary.	LHCGR FSHR	3.96e-05	4	90	2	15232063
Pubmed	ZDHHC11 modulates innate immune response to DNA virus by mediating MITA-IRF3 association.	ZDHHC11B ZDHHC11	3.96e-05	4	90	2	29429998
Pubmed	The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stress.	ZFHX3 ATM	3.96e-05	4	90	2	20876357
Pubmed	β-arrestins regulate gonadotropin receptor-mediated cell proliferation and apoptosis by controlling different FSHR or LHCGR intracellular signaling in the hGL5 cell line.	LHCGR FSHR	3.96e-05	4	90	2	27502035
Pubmed	Correlation of C4ST-1 and ChGn-2 expression with chondroitin sulfate chain elongation in atherosclerosis.	CSGALNACT2 CSGALNACT1	3.96e-05	4	90	2	21284936
Pubmed	IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses.	IL13RA2 TMEM219	3.96e-05	4	90	2	27629921
Pubmed	Distribution of group-III metabotropic glutamate receptors in the retina.	GRM6 GRM7	3.96e-05	4	90	2	17311335
Pubmed	Antagonistic interactions between osterix and pyrophosphate during cementum formation.	FGFR1 ANKH	6.59e-05	5	90	2	31059863
Pubmed	Cytochromes b561: ascorbate-mediated trans-membrane electron transport.	CYB561D1 CYB561A3	6.59e-05	5	90	2	23249217
Pubmed	Galectin-3 Interacts with the CHI3L1 Axis and Contributes to Hermansky-Pudlak Syndrome Lung Disease.	IL13RA2 TMEM219	6.59e-05	5	90	2	29427412
Pubmed	The human olfactory receptor gene family.	OR10G6 OR6B1 OR4N2 OR4N4 OR1C1 OR8B12 OR8U3 OR14A16	8.26e-05	541	90	8	14983052
Pubmed	Pias1 interaction and sumoylation of metabotropic glutamate receptor 8.	GRM6 GRM7	9.87e-05	6	90	2	16144832
Pubmed	Cornichon proteins determine the subunit composition of synaptic AMPA receptors.	CNIH2 CNIH3	9.87e-05	6	90	2	23522044
Pubmed	ZDHHC11 Positively Regulates NF-κB Activation by Enhancing TRAF6 Oligomerization.	ZDHHC11B ZDHHC11	9.87e-05	6	90	2	34490261
Pubmed	Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating.	CNIH2 CNIH3	9.87e-05	6	90	2	20805473
Pubmed	Dissociation of heterotrimeric g proteins in cells.	LHCGR VIPR2 ADORA3 UTS2 FSHR	1.05e-04	179	90	5	18577758
Pubmed	Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfate.	CSGALNACT2 UST CSGALNACT1	1.22e-04	37	90	3	32201365
Pubmed	Chondroitin sulfate N-acetylgalactosaminyltransferase-1 plays a critical role in chondroitin sulfate synthesis in cartilage.	CSGALNACT2 CSGALNACT1	1.38e-04	7	90	2	17145758
Pubmed	Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3.	LHCGR FSHR	1.38e-04	7	90	2	21151128
Pubmed	Chondroitin sulfate N-acetylgalactosaminyltransferase-1 is required for normal cartilage development.	CSGALNACT2 CSGALNACT1	1.38e-04	7	90	2	20812917
Pubmed	Metabotropic glutamate receptor subtype 7 ablation causes deficit in fear response and conditioned taste aversion.	GRM6 GRM7	1.38e-04	7	90	2	9920659
Pubmed	In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes.	ZDHHC11B ZDHHC11	1.38e-04	7	90	2	23687301
Pubmed	Fgf and Wnt signaling interaction in the mesenchymal niche regulates the murine hair cycle clock.	CORIN FGFR1	1.38e-04	7	90	2	33037205
Pubmed	Chondroitin sulfate N-acetylgalactosaminyltransferase 1 is necessary for normal endochondral ossification and aggrecan metabolism.	CSGALNACT2 CSGALNACT1	1.38e-04	7	90	2	21148564
Pubmed	Biosynthesis of chondroitin sulphate by a Golgi-apparatus-enriched preparation from cultures of mouse mastocytoma cells.	CSGALNACT2 CSGALNACT1	1.84e-04	8	90	2	6781479
Pubmed	Mouse minipuberty coincides with gonocyte transformation into spermatogonial stem cells: a model for human minipuberty.	LHCGR FSHR	1.84e-04	8	90	2	28531375
Pubmed	A mouse knockout library for secreted and transmembrane proteins.	ZDHHC11B UTS2 CNIH1 SLC49A3 ZDHHC11 IL22RA1 CSGALNACT1	1.97e-04	460	90	7	20562862
Pubmed	Neuregulin 1 Regulates Proliferation of Leydig Cells to Support Spermatogenesis and Sexual Behavior in Adult Mice.	LHCGR FSHR	2.36e-04	9	90	2	27732090
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR10G6 OR6B1 OR4N2 OR2V1 OR8B12 OR8U3	2.61e-04	340	90	6	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR10G6 OR6B1 OR4N2 OR2V1 OR8B12 OR8U3	2.61e-04	340	90	6	11802173
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	LRP12 CSGALNACT2 CALU SCARB2 CD151 TIMELESS ATM ADGRE2 UST CSGALNACT1 HTT	2.73e-04	1201	90	11	35696571
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR10G6 OR6B1 OR4N2 OR2V1 OR8B12 OR8U3	2.73e-04	343	90	6	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR10G6 OR6B1 OR4N2 OR2V1 OR8B12 OR8U3	2.86e-04	346	90	6	14611657
Pubmed	Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.	GRM6 GRM7	2.94e-04	10	90	2	9069281
Pubmed	The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis.	VIPR2 ZFHX3	3.59e-04	11	90	2	26232227
Pubmed	Dysregulated cell signalling and reduced satellite cell potential in ageing muscle.	SULF1 FGFR1	4.30e-04	12	90	2	31647919
Pubmed	Postnatal lethality and chondrodysplasia in mice lacking both chondroitin sulfate N-acetylgalactosaminyltransferase-1 and -2.	CSGALNACT2 CSGALNACT1	4.30e-04	12	90	2	29287114
Pubmed	Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome.	LHCGR FSHR	5.07e-04	13	90	2	22885925
Pubmed	Genome-wide association study identifies three new melanoma susceptibility loci.	ATM TERT	5.91e-04	14	90	2	21983787
Pubmed	Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors.	SULF1 FGFR1	8.78e-04	17	90	2	30838872
Pubmed	Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.	CALU MRGPRF CNIH1 ALG8 CYB561A3 TMBIM1	8.96e-04	430	90	6	16303743
Interaction	BIK interactions	BMP10 CNIH1 ALG8 ADGRE2 SEC22A TMBIM1 CNIH3	9.41e-07	132	80	7	int:BIK
Interaction	GPX8 interactions	RNF130 BMP10 SCARB2 CNIH1 CORIN ALG8 CYB561A3 CNIH3 VSTM1	1.35e-06	273	80	9	int:GPX8
Interaction	AQP6 interactions	BMP10 CNIH1 CYB561D1 CORIN ADGRE2 CYB561A3 SEC22A CNIH3 VSTM1	6.34e-06	330	80	9	int:AQP6
Interaction	TMEM59 interactions	RNF130 LRP12 CSGALNACT2 SGCA LMBR1 FGFR1 UST	7.67e-06	181	80	7	int:TMEM59
Interaction	GGT6 interactions	BMP10 SEC22A TMBIM1	2.12e-05	14	80	3	int:GGT6
Cytoband	5p15.33	ZDHHC11B ZDHHC11 TERT	3.35e-05	32	89	3	5p15.33
Cytoband	3p25.2	CAND2 TAMM41	2.02e-04	11	89	2	3p25.2
Cytoband	Ensembl 112 genes in cytogenetic band chr5p15	ZDHHC11B ZDHHC11 TERT ANKH	6.88e-04	204	89	4	chr5p15
GeneFamily	Glycoprotein hormone receptors	LHCGR FSHR	3.81e-05	3	65	2	199
GeneFamily	Zinc fingers DHHC-type\|Ankyrin repeat domain containing	ZDHHC11B ZDHHC19 ZDHHC11	8.50e-05	24	65	3	76
GeneFamily	Cytochrome b561	CYB561D1 CYB561A3	1.26e-04	5	65	2	497
GeneFamily	Glutamate metabotropic receptors\|Protein phosphatase 1 regulatory subunits	GRM6 GRM7	3.51e-04	8	65	2	281
GeneFamily	Beta 4-glycosyltransferases	CSGALNACT2 CSGALNACT1	1.67e-03	17	65	2	425
ToppCell	TCGA-Breast-Metastatic-Breast_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	LHCGR BMP10 FSHR ZDHHC19 RXFP1	1.05e-05	149	86	5	c7dc495141cd921b6b6f291a68851b7b807d0d0a
ToppCell	TCGA-Breast-Metastatic-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	LHCGR BMP10 FSHR ZDHHC19 RXFP1	1.05e-05	149	86	5	2e9b898f3df22f8e872f2c278eff454c39e55b3b
ToppCell	TCGA-Breast-Metastatic\|TCGA-Breast / Sample_Type by Project: Shred V9	LHCGR BMP10 FSHR ZDHHC19 RXFP1	1.05e-05	149	86	5	144ac2c458209ce510674bc2f83eb4c8e4d3c953
ToppCell	PND07-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LRP12 TMEM219 TAMM41 ATM TTC19	1.27e-05	155	86	5	b5d5c38b269e9318970fcce564df1c8ed7a7ccc6
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_12\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	UTS2 PAQR4 SLC12A8 KCNK13 GRM7	1.52e-05	161	86	5	1670108afc0af90861eb80a84e59995571c0da1b
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_12\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	UTS2 PAQR4 SLC12A8 KCNK13 GRM7	1.52e-05	161	86	5	1d446f5ba57d84949823a35cbedaee8f448fe40f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZFHX3 KCNK13 FGFR1 RXFP1 UST	1.81e-05	167	86	5	a6ff7a3d9b80839c0efa91658836812e868561fa
Disease	Paroxysmal atrial fibrillation	CAND2 SGCA CALU ZFHX3 UST	6.37e-05	156	79	5	C0235480
Disease	familial atrial fibrillation	CAND2 SGCA CALU ZFHX3 UST	6.37e-05	156	79	5	C3468561
Disease	Persistent atrial fibrillation	CAND2 SGCA CALU ZFHX3 UST	6.37e-05	156	79	5	C2585653
Disease	Atrial Fibrillation	CAND2 SGCA CALU ZFHX3 UST	7.18e-05	160	79	5	C0004238
Disease	granulosa cell tumor (is_marker_for)	LHCGR FSHR	3.83e-04	11	79	2	DOID:2999 (is_marker_for)
Disease	Myeloproliferative disease	FGFR1 TERT	4.59e-04	12	79	2	C0027022
Disease	cognitive behavioural therapy	GPR149 ZFHX3 FGFR1	5.13e-04	58	79	3	EFO_0007820
Disease	lung non-small cell carcinoma (is_implicated_in)	ZFHX3 FGFR1 ATM TERT	5.39e-04	139	79	4	DOID:3908 (is_implicated_in)
Disease	Endometrioma	RXFP1 UST ANKH CNIH3	9.33e-04	161	79	4	C0269102
Disease	Endometriosis	RXFP1 UST ANKH CNIH3	9.33e-04	161	79	4	C0014175
Disease	Depressive disorder	ALG8 TIMELESS FGFR1 GRM7 HTT	1.09e-03	289	79	5	C0011581
Disease	Disproportionate short stature	SULF1 FGFR1 ANKH	1.17e-03	77	79	3	C0878659
Disease	Glioma	FGFR1 ATM TERT	1.67e-03	87	79	3	C0017638
Disease	Etat Marbre	UTS2 HTT	1.73e-03	23	79	2	C0266487
Disease	lung squamous cell carcinoma (is_implicated_in)	ATM TERT	1.88e-03	24	79	2	DOID:3907 (is_implicated_in)
Disease	myeloproliferative disorder	ATM TERT	2.04e-03	25	79	2	EFO_0004251

Protein segments in the cluster

Peptide	Gene	Start	Entry
LAFCLCMAEAILLFS	CYB561D1	61	Q8N8Q1
LLCCAISVLYMLACT	CSGALNACT1	21	Q8TDX6
YFALCLSLMVGSLLE	HTR3E	311	A5X5Y0
YSCLFMTCLLLIFTH	ADORA3	81	P0DMS8
YMGLSVSLLCLLLAA	ADGRE2	541	Q9UHX3
MCALYASLALLSGLS	GSDMD	466	P57764
VYACTAVMLLCLLAS	ADGRA1	21	Q86SQ6
ICLLVLGALCLYFSM	B3GALT5	11	Q9Y2C3
FLMCLSLCTAFALSK	CALU	6	O43852
MAFVCLAIGCLYTFL	IL13RA2	1	Q14627
LTYKLALCLCMINFY	RAB3GAP1	456	Q15042
MTLLCFLGLLASYAV	OR4N4C	206	A0A096LPK9
SFGLLSALTLCYMII	RNF130	391	Q86XS8
LSFADFCMGLYLLLI	LHCGR	401	P22888
FCMGLYLLLIASVDS	LHCGR	406	P22888
ALGCTCKLYSLRMFE	LRP12	511	Q9Y561
MLYAALGAICFTLFL	TMBIM1	251	Q969X1
ALYLMCTVPAFCRLT	NLRC3	321	Q7RTR2
PYLYSCISLMGCLLL	LMBR1	191	Q8WVP7
CIILGCFMACLLIYI	FUT9	16	Q9Y231
LLFCLVMASCQYSLL	PCNX2	871	A6NKB5
FDTLLFACCVFMLLL	OR2V1	196	Q8NHB1
MTLLCFLGLLASYAV	OR4N2	206	Q8NGD1
MTLLCFLGLLASYAV	OR4N4	206	Q8N0Y3
YVMLILCTASILISC	KCNK13	196	Q9HB14
LGCFLAFMTAECLLL	OR8U9	101	P0C7N5
VYARLLALDMCGVCL	PAQR4	111	Q8N4S7
TLNIYLFCLTCLMTF	GPR149	31	Q86SP6
LFCLTCLMTFAALVG	GPR149	36	Q86SP6
LLFLALFGVSLYSMC	NPC1L1	851	Q9UHC9
YTVTMSCQVCLLLLL	OR8B12	131	Q8NGG6
SCQVCLLLLLGAYGM	OR8B12	136	Q8NGG6
LFLDMLKFLCLCVTT	ATM	896	Q13315
LLCSLVLFMYLLECA	CSGALNACT2	21	Q8N6G5
FYCQELGTLLMCLIH	HTT	1771	P42858
LIGCLGYSLLLMVTC	GRM6	751	O15303
MGSLVLTLCALFCLA	BMP10	1	O95393
EIIIYCTGAFLISCM	FGFR1	376	P11362
SLYMGALVRCTTLCL	ANKH	196	Q9HCJ1
LSCYQHIMLFGCTLA	CORIN	181	Q9Y5Q5
LFSMGFLVAVLCYLS	IL22RA1	236	Q8N6P7
IICSLGYSILLMVTC	GRM7	756	Q14831
FYLSCLLLGSLGSMC	CYB561A3	6	Q8NBI2
MCNLAFADLCIGIYL	FSHR	401	P23945
FGMIFTCCLYRSLKL	CD151	236	P48509
FECMYSLLESCLGQL	CAND2	1091	O75155
SFLTFGLICLCNMYL	SEC22A	256	Q96IW7
LFLLGLYISSLASCM	SLC12A8	311	A0AV02
LLSVLFLCMYLATTL	OR1C1	26	Q15619
FLALTCFMLILTSYG	OR10G6	226	Q8NH81
MCILHSILFLLIYLC	OR14A16	21	Q8NHC5
LLCAIYFLSMIISVC	TAS2R30	236	P59541
LLCAIYFLSMIISVC	TAS2R36	236	P0DTE0
CIGSMLSFEYLIQLC	SZT2	946	Q5T011
MYKLASCCLLFIGFL	UTS2	1	O95399
LSCFLGFLLMYSTVL	SLC35D2	246	Q76EJ3
LLFLMGGTFCIISLC	TMEM178B	206	H3BS89
LYLLLRGSCLNCHML	POLR1A	96	O95602
DLEIGMYALLCVFCL	TMEM132B	896	Q14DG7
MYALLCVFCLAILVF	TMEM132B	901	Q14DG7
CALSMYASVLLTGLL	LTB4R2	101	Q9NPC1
VMNYIFLLLCLCGLV	MRGPRF	46	Q96AM1
MGRCCFYTAGTLSLL	SCARB2	1	Q14108
LLGTCLLYCARSSMP	SLC17A9	31	Q9BYT1
LLLMSISCLCPFYLI	PIGC	256	Q92535
IALLFVAFALCMFCL	SLC35F2	261	Q8IXU6
LGCFLTFMITECFLL	OR8U3	101	Q8NH85
LYFFIALMCTECVLL	OR6B1	101	O95007
LSYGCILATILCMPT	OR6B1	216	O95007
ALLLTLLLAYVMCCR	SGCA	301	Q16586
GFLRCLTLCALSSFM	ALG8	361	Q9BVK2
AAFCYMLALLLTAAL	CNIH1	6	O95406
AAFCYMLTLVLCASL	CNIH2	6	Q6PI25
AAFCYMLSLVLCAAL	CNIH3	6	Q8TBE1
FLLLATCLLFMTLCK	C10orf105	46	Q8TEF2
LMAGLCTFFSCILAV	SLC49A3	426	Q6UXD7
CMATLLVFCLGSLLY	UST	51	Q9Y2C2
MNCELLATCSALGYL	TIMELESS	6	Q9UNS1
LGMCLDACARYLLFS	TTC19	236	Q6DKK2
AFLLTSALMGILCCF	SMIM9	76	A6NGZ8
SLCCADCLMGIYLFV	RXFP1	446	Q9HBX9
LIALSFLAPCMCCYL	SPRED2	381	Q7Z698
CKALYLLGACEMLSF	TAMM41	336	Q96BW9
MTAEFLSLLCLGLCL	VSTM1	1	Q6UX27
GCKLSLVFLQYCIMA	VIPR2	201	P41587
SATAGMLCLIAILLY	ZDHHC11	176	Q9H8X9
MLLSFLCCRVLLFPY	TLCD3B	196	Q71RH2
FFMLLVLSLCLYSGA	ZDHHC19	156	Q8WVZ1
VLSLCLYSGAMLVTC	ZDHHC19	161	Q8WVZ1
FLLLFCGLLCCVTAM	TMEM219	211	Q86XT9
YLLCGLLSSSFITCM	TVP23B	51	Q9NYZ1
SATAGMLCLIAILLY	ZDHHC11B	176	P0C7U3
SMLSFISATCLLLCL	TMEM202	156	A6NGA9
MKYSCCALVLAVLGT	SULF1	1	Q8IWU6
ILSTLLCSLCYGDME	TERT	836	O14746
ILMCFLCKLSFGYVR	ZFHX3	281	Q15911