Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity

ALG10 ALG10B

6.91e-062532GO:0106073
DomainAlg10

ALG10 ALG10B

7.90e-062532IPR016900
DomainDIE2_ALG10

ALG10 ALG10B

7.90e-062532PF04922
DomainLipase_panc

PNLIP PNLIPRP1

4.72e-054532IPR002331
DomainLipase/vitellogenin

PNLIP PNLIPRP1

3.50e-0410532IPR013818
DomainTAG_lipase

PNLIP PNLIPRP1

3.50e-0410532IPR000734
DomainLipase_LIPH

PNLIP PNLIPRP1

3.50e-0410532IPR016272
DomainLipase

PNLIP PNLIPRP1

3.50e-0410532PF00151
DomainLipase_N

PNLIP PNLIPRP1

3.50e-0410532IPR033906
DomainLH2

PNLIP PNLIPRP1

1.17e-0318532SM00308
DomainPLAT

PNLIP PNLIPRP1

1.60e-0321532PS50095
Domain-

PNLIP PNLIPRP1

1.60e-03215322.60.60.20
DomainPLAT

PNLIP PNLIPRP1

1.60e-0321532PF01477
DomainPLAT/LH2_dom

PNLIP PNLIPRP1

1.60e-0321532IPR001024
DomainPeptidase_M14

AGBL1 AGTPBP1

1.92e-0323532PF00246
DomainPeptidase_M14

AGBL1 AGTPBP1

1.92e-0323532IPR000834
DomainLIPASE_SER

PNLIP PNLIPRP1

2.46e-0326532PS00120
Domain-

SGTB PSMD3 TANC1 COA7

2.81e-032075341.25.40.10
DomainTPR-like_helical_dom

SGTB PSMD3 TANC1 COA7

4.28e-03233534IPR011990
Domain-

DPP4 PNLIP PNLIPRP1

4.69e-031195333.40.50.1820
DomainAB_hydrolase

DPP4 PNLIP PNLIPRP1

4.69e-03119533IPR029058
Pubmed

Pancreatic lipase and its related proteins: where are we now?

PNLIP PNLIPRP1

7.36e-06355238081381
Pubmed

A point mutation in the gene for asparagine-linked glycosylation 10B (Alg10b) causes nonsyndromic hearing impairment in mice (Mus musculus).

ALG10 ALG10B

7.36e-06355224303013
Pubmed

Integration of metabolomics and transcriptomics revealed a fatty acid network exerting growth inhibitory effects in human pancreatic cancer.

PNLIP PNLIPRP1

7.36e-06355223918603
Pubmed

Two novel human pancreatic lipase related proteins, hPLRP1 and hPLRP2. Differences in colipase dependence and in lipase activity.

PNLIP PNLIPRP1

7.36e-0635521379598
Pubmed

Cloning of an interleukin-4 inducible gene from cytotoxic T lymphocytes and its identification as a lipase.

PNLIP PNLIPRP1

7.36e-0635522302735
Pubmed

Changes in CD73, CD39 and CD26 expression on T-lymphocytes of ANCA-associated vasculitis patients suggest impairment in adenosine generation and turn-over.

DPP4 ENTPD1

7.36e-06355228916770
Pubmed

IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes.

DPP4 TLR7

7.36e-06355231355779
Pubmed

Expression of TLR7, TLR9, JAK2, and STAT3 genes in peripheral blood mononuclear cells from patients with systemic sclerosis.

JAK2 TLR7

1.47e-05455229147913
Pubmed

The IKr drug response is modulated by KCR1 in transfected cardiac and noncardiac cell lines.

ALG10 ALG10B

1.47e-05455214525949
Pubmed

Cytokine receptor-like factor 1 (CRLF1) protects against 6-hydroxydopamine toxicity independent of the gp130/JAK signaling pathway.

JAK2 CRLF1

1.47e-05455223818941
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ZNF462 JAK2 ERV3-1 MBNL2 ENTPD1 NAT10 ASH1L TANC1 GREB1 UQCRC1 PFKL

1.80e-051489551128611215
Pubmed

Large-scale investigation of genomic markers for severe periodontitis.

DPP4 FGL2

2.45e-05555215490304
Pubmed

Modulation of cytokine release and gene expression by the immunosuppressive domain of gp41 of HIV-1.

TLR7 MS4A6A PTGFRN FGL2

2.65e-0510855423383108
Pubmed

Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells.

LPAR6 ENTPD1

3.67e-05655211004484
Pubmed

A novel subfamily of mouse cytosolic carboxypeptidases.

AGBL1 AGTPBP1

3.67e-05655217244818
Pubmed

Assignment of the mouse vesicular monoamine transporter genes, Slc18a1 and Slc18a2, to chromosomes 8 and 19 by linkage analysis.

PNLIP PNLIPRP1

3.67e-0565528661734
Pubmed

The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids.

AGBL1 AGTPBP1

3.67e-05655225103237
Pubmed

Assignment of Gpam to distal mouse chromosome 19 by linkage analysis.

PNLIP PNLIPRP1

3.67e-0565529434961
Pubmed

The carboxypeptidase-like substrate-binding site in Nna1 is essential for the rescue of the Purkinje cell degeneration (pcd) phenotype.

AGBL1 AGTPBP1

3.67e-05655216952463
Pubmed

A family of protein-deglutamylating enzymes associated with neurodegeneration.

AGBL1 AGTPBP1

5.13e-05755221074048
Pubmed

Glutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunity.

AGBL1 AGTPBP1

8.78e-05955226829768
Pubmed

A cluster of stearoyl CoA desaturase genes, Scd1 and Scd2, on mouse chromosome 19.

PNLIP PNLIPRP1

8.78e-0595529530639
Pubmed

IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development.

AGBL1 AGTPBP1

1.60e-041255228794449
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ZNF34 NEUROD2 SGTB TRPM7 ASH1L SH3GLB2 UQCRC1 UBASH3A AGTPBP1

1.71e-04128555935914814
Pubmed

Chromosomal localization of lipolytic enzymes in the mouse: pancreatic lipase, colipase, hormone-sensitive lipase, hepatic lipase, and carboxyl ester lipase.

PNLIP PNLIPRP1

2.21e-04145528105016
Pubmed

Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice.

ZNF462 ASH1L

2.90e-041655216096065
Pubmed

HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis.

NAT10 PSMD3 GCN1

3.61e-048755333711283
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NWD2 TANC1 GCN1

3.61e-048755312465718
Pubmed

Functional genetic analysis of mouse chromosome 11.

ALG10 ALG10B

6.08e-042355212955145
Pubmed

Quantitative trait loci for obesity- and diabetes-related traits and their dietary responses to high-fat feeding in LGXSM recombinant inbred mouse strains.

CD55 TLR7

6.63e-042455215561968
Pubmed

Genome-wide association study of proneness to anger.

PNLIP PNLIPRP1

6.63e-042455224489884
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

ARHGEF12 SH3GLB2 PSMD3 PFKL

6.77e-0425155429778605
Pubmed

Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.

FCRL3 UBASH3A

7.20e-042555221829393
Pubmed

Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.

AGBL1 AGTPBP1

7.20e-042555229593216
Pubmed

UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target.

PFKL GCN1

1.04e-033055232867711
Pubmed

DR3 signaling modulates the function of Foxp3+ regulatory T cells and the severity of acute graft-versus-host disease.

ENTPD1 FGL2

1.26e-033355227760760
Pubmed

The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis.

PNLIP PNLIPRP1

1.49e-033655225063451
GeneFamilyAlpha-1,2-glucosyltransferases

ALG10 ALG10B

4.53e-062392448
GeneFamilyADAM metallopeptidase domain containing|CD molecules

DPP4 FCRL3 ENTPD1 CD55 PTGFRN

1.50e-03394395471
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF462 ZNF34 RBAK ZFPM1 ZNF112 ZFY

4.09e-0371839628
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KCTD19 ENTPD1 MS4A6A AGTPBP1 FGL2

1.51e-061615453a5f2877e3b29463a3a6da05009b0ab8747b4c47
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

CD55 ARHGEF12 ADGRF5 TANC1 ZFY

1.98e-06170545e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 LPAR6 CD55 ADGRF5 TANC1

2.69e-06181545a53f05c4c47465ee62e353716456bd09ab464b23
ToppCellDendritic_Cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

LPAR6 ENTPD1 TLR7 MS4A6A FGL2

3.49e-06191545b51c8ff1279581088557bb36760c70209c77148c
ToppCellChildren_(3_yrs)-Immune-monocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

JAK2 ENTPD1 MS4A6A AGTPBP1 FGL2

3.68e-0619354558e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCell356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

LPAR6 ENTPD1 TLR7 MS4A6A FGL2

3.77e-0619454511ff53a748160570d2908ea9eb9779c038e5b676
ToppCelldroplet-Bladder-Unstain-18m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTMR7 CRLF1 ENTPD1 ADGRF5 FGL2

3.77e-061945459d7cbbcf995274019ca10be0562f114513ec197a
ToppCell356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|356C / Donor, Lineage, Cell class and subclass (all cells)

LPAR6 ENTPD1 TLR7 MS4A6A FGL2

3.87e-061955459231e929657542b78a6480d44402866511129c7f
ToppCell(3)_Macrophage_MARCOneg|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

LPAR6 ENTPD1 TLR7 MS4A6A FGL2

4.06e-06197545b0ee2ce1179b60b4542559acb300a34295277dbc
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PNLIPRP1 LPAR6 ENTPD1 MS4A6A FGL2

4.06e-06197545e2c53742c7d8d1b63d93843f82330b9e20f1faa6
ToppCellwk_15-18-Hematologic-Myeloid-CX3CR1+_Mac|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

LPAR6 ENTPD1 TLR7 MS4A6A FGL2

4.06e-06197545701334bc164e3b41132232f27574a87e9c3a5be5
ToppCellcontrol-HLA-DR+_CD83+_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

JAK2 ENTPD1 MS4A6A PGBD5 FGL2

4.27e-06199545f1b370d2869ad29c9d8ff41fdcc486fffa781ee2
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LPAR6 ENTPD1 TLR7 MS4A6A FGL2

4.37e-06200545a2548b0c77ba1616638351b111cce2fe0cacaa95
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LPAR6 ENTPD1 TLR7 MS4A6A FGL2

4.37e-06200545e4a499b69554f78161c2c47199da77c201910e73
ToppCell10x5'-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

LPAR6 ZNF112 MS4A6A FGL2

2.59e-051415447671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCellMonocytes-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

JAK2 LPAR6 FGL2

2.90e-0549543bf67f5dee042fd680c661db637fde715e48b14c5
ToppCellMonocytes-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

ENTPD1 EQTN MS4A6A FGL2

3.30e-05150544b580b06795973fec16ea6f7f5b6b9d580bf7fcf5
ToppCellnormal_Lymph_Node-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

TRPM7 LPAR6 MS4A6A FGL2

3.56e-051535445424494ea1f09542799045a875cc3eac13de5079
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-midbrain/hindbrain_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

NWD2 EML5 MS4A6A FGL2

3.65e-05154544df1b58a20af73fa79c6c069c0117a9ffd85b476f
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NT5C1A KCTD19 CD55 ADGRF5

3.75e-051555448fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Lymphocytic-T_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCTD19 UBASH3A AGBL1 PGBD5

3.84e-051565440bd32876413f3308f838f266e8c39ea0937ce5b9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MTMR7 CPHXL2 ALG10 COA7

3.84e-05156544d34f386985dd17293b1e320d732ab11b46be76ce
ToppCellDendritic_Cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

LPAR6 ENTPD1 MS4A6A FGL2

4.89e-05166544fbeb74b98b58085de323f744b18d4a8f7b22d5d4
ToppCellDendritic_Cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

LPAR6 ENTPD1 MS4A6A FGL2

5.13e-0516854433618e5dbcee31f30afacacc9f6046782c100fb3
ToppCell390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|390C / Donor, Lineage, Cell class and subclass (all cells)

LPAR6 ENTPD1 TLR7 MS4A6A

5.25e-051695442c851b2703c7b8b656026f996f5fc027e4a79b36
ToppCell3'_v3-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

LPAR6 ENTPD1 MS4A6A FGL2

5.25e-05169544241644823e6f949aaf4c671d4579721d7ef6b0e5
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MTMR7 NWD2 PNLIPRP1 MED12L

5.62e-051725441bbf5ed7d13635f9a7e528060341e0652699bd7c
ToppCelldroplet-Lung-nan-21m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAK2 DPP4 MED12L FGL2

5.88e-051745442afa5eea54b67c549c5058ece98296eee3829c11
ToppCellDendritic_Cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

LPAR6 ENTPD1 MS4A6A FGL2

6.01e-05175544584290a51f9975782a5ac8c6ad67c778d8323f8c
ToppCellDendritic_Cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

LPAR6 ENTPD1 MS4A6A FGL2

6.28e-05177544d2cd081bdda0eba9f6f6473c4d3939e4bee3440e
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTMR7 CD55 TLR7 ALG10B

6.28e-05177544c2b8a3a149d70f77612759dea34df9e43953c566
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTMR7 CD55 TLR7 ALG10B

6.28e-05177544384f841aa7b2d05815af7885e481f5affc55d897
ToppCellfacs-Thymus-Epithelium-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTMR7 CD55 TLR7 ALG10B

6.28e-051775440e9e44119653abfd270e602e5e477a15e774638f
ToppCellDendritic_Cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

LPAR6 ENTPD1 MS4A6A FGL2

6.42e-0517854461ce3ec64c4cffceac08412e20c26e9c90ab8197
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LPAR6 ENTPD1 MS4A6A FGL2

6.56e-05179544409364d916c5e7e2291284cc74351d8f8a8447ac
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAK2 DPP4 CD55 ADGRF5

6.85e-05181544fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TLR7 ZFPM1 MS4A6A FGL2

7.00e-051825444a85429d365c4b2d73fc921f261b4b7635ac40bd
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TLR7 ZFPM1 MS4A6A FGL2

7.00e-0518254453213af34af3337f5edc734d3b7b79e4349eac0d
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRLF1 EML5 MED12L PGBD5

7.00e-05182544be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TLR7 ZFPM1 MS4A6A FGL2

7.00e-051825447909089ed6325c44edd6f9b7e8b1d542398222ea
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 LPAR6 CD55 ADGRF5

7.15e-05183544709a486154b3157427deb3b8886b63ac39ea42dd
ToppCelldroplet-Liver-nan-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 LPAR6 CD55 ADGRF5

7.15e-05183544dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCellCOVID-19-APC-like-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

ENTPD1 MED12L MS4A6A FGL2

7.15e-05183544703364836b42aa6ac6c68b42b700ac23c4a1afc7
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

C17orf75 SGTB CCDC82 ENTPD1

7.15e-05183544f142b320023eef00b48d4820c46214c9794d37e7
ToppCellControl-APC-like-Dendritic_cells|Control / group, cell type (main and fine annotations)

ENTPD1 MED12L MS4A6A FGL2

7.15e-051835448f9c8e2436f18ea7c265b08e4e149e19cb513a16
ToppCellControl-APC-like|Control / group, cell type (main and fine annotations)

ENTPD1 MED12L MS4A6A FGL2

7.15e-05183544c313ac72cc9fa1583456d452393f61f0a4ca33a8
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LPAR6 ENTPD1 MED12L FGL2

7.15e-05183544bd78e5c2670e67b4363078e3ca5a5b7081d24b7e
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LPAR6 ENTPD1 MED12L FGL2

7.15e-05183544d1bf3abf42eb9d7facf775becf1338d1faadd647
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PNLIP CD55 ZNF112 FGL2

7.15e-05183544919c9861073d12fd12aecd7469b1478b13838c43
ToppCellCOVID-19-APC-like|COVID-19 / group, cell type (main and fine annotations)

ENTPD1 MED12L MS4A6A FGL2

7.15e-05183544b8f5afaf9ff1b2b1bc60be58654d1b23859dafa9
ToppCellCOPD-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

ENTPD1 CD55 AGTPBP1 FGL2

7.30e-05184544ceec41ed5636032aaf7716d1203816ea58bd39bd
ToppCellfacs-Thymus|facs / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PNLIP PNLIPRP1 LPAR6 UBASH3A

7.30e-0518454458beef66bbbde2479ec69dfef392d5941cedf230
ToppCellDendritic_Cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

LPAR6 ENTPD1 MS4A6A FGL2

7.45e-05185544952ded6830b5cabf64d153fc2e003e681e4370a2
ToppCell343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|343B / Donor, Lineage, Cell class and subclass (all cells)

LPAR6 TLR7 MS4A6A FGL2

7.45e-05185544d4ba36bdb8b7e3a62e827269484f89f790eaa5ef
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD4-positive,_alpha-beta_T_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DPP4 SGTB LPAR6 UBASH3A

7.45e-05185544608c16c0ff251926e3e62a6cb66f835163302538
ToppCellIPF-Epithelial-ATII|World / Disease state, Lineage and Cell class

DPP4 ADGRF5 TANC1 AGBL1

7.61e-051865446a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCellDendritic_Cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

LPAR6 ENTPD1 MS4A6A FGL2

7.61e-051865441d52912bd17e232cf39b2423a4d93585c164ba34
ToppCell15-Trachea-Epithelial-Secretory_progenitor|Trachea / Age, Tissue, Lineage and Cell class

CRLF1 ERV3-1 CD55 ADGRF5

7.77e-05187544be9fce9e74b2f170a2067f1b31d802912a578329
ToppCellLAM-Myeloid-DC|LAM / Condition, Lineage and Cell class

LPAR6 ENTPD1 MS4A6A FGL2

7.93e-05188544b4140110c2f7d25fd8a0d2749e33e02003ac4bf2
ToppCellControl-Myeloid-cMonocyte|Myeloid / Disease state, Lineage and Cell class

CD55 MS4A6A AGTPBP1 FGL2

7.93e-0518854447126c371a242c937499fd278a74a882df8f759c
ToppCell356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LPAR6 ENTPD1 TLR7 MS4A6A

8.26e-05190544d541e076137cf7334bdb0ed69db2f9a27c668c65
ToppCellIPF-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

CD55 MS4A6A AGTPBP1 FGL2

8.26e-05190544ffa890138394f579fee53fcfac6c121bf86adc26
ToppCellIPF-Myeloid-cMonocyte|IPF / Disease state, Lineage and Cell class

CD55 MS4A6A AGTPBP1 FGL2

8.26e-05190544a099f51f2b7618b6712af38eedd5ee64d8663a4a
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|368C / Donor, Lineage, Cell class and subclass (all cells)

LPAR6 ENTPD1 MS4A6A FGL2

8.26e-05190544cbba3d94a4c3e0b0d14f3b7c60dba5d6e097c5e3
ToppCell(3)_MNP-(3)_DC_2|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

LPAR6 ENTPD1 MS4A6A FGL2

8.43e-051915443ff163484af8c12ef4eef87246cf044257fd2547
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LPAR6 TLR7 MS4A6A FGL2

8.43e-0519154494c7da03e5264f4d73bb507ce339a935d90279a0
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PNLIP PNLIPRP1 PTGFRN

8.45e-057054326178ee967d647224d93c7a6380f2d15d8fcfb8f
ToppCellControl-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

ARHGEF12 ADGRF5 TANC1 AGBL1

8.60e-051925441bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LPAR6 ENTPD1 MS4A6A FGL2

8.60e-05192544314d94d676d13f4ca0eea8ba222c7eb00946849c
ToppCellFetal_29-31_weeks-Immune-monocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LPAR6 ENTPD1 MS4A6A FGL2

8.60e-051925445417f024fcc89eaeab33f4a2c6421d1cfabd681b
ToppCellControl-Myeloid-cMonocyte|Control / Disease state, Lineage and Cell class

CD55 MS4A6A AGTPBP1 FGL2

8.60e-05192544ad04c9c4bdebf94615cee1904ca48197e62c923b
ToppCellMNPs-Dendritic_Cells|MNPs / lung cells shred on cell class, cell subclass, sample id

LPAR6 ENTPD1 MS4A6A FGL2

8.78e-051935440e6b8e179bfe1c6e93137c76c76a91c7782a4989
ToppCell11.5-Airway-Epithelial-Bud_tip_progenitor|Airway / Age, Tissue, Lineage and Cell class

DPP4 CRLF1 CD55 ADGRF5

8.78e-05193544f0a07bb221a497a9f7cc706045d5205269be4515
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LPAR6 TLR7 MS4A6A FGL2

8.78e-05193544fc2eb6a7b4f1e687bf37e59e3cd52b14f99ffea4
ToppCellLAM-Myeloid-DC|Myeloid / Condition, Lineage and Cell class

LPAR6 ENTPD1 MS4A6A FGL2

8.78e-05193544f665cce40053ae5d6e28f9f70ddf78e8598c9514
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LPAR6 ENTPD1 MS4A6A FGL2

8.78e-051935442d0dd2671ff27b922eb316f1ed0140353536ef30
ToppCellfacs-Liver-Non-hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 CD55 ADGRF5 TANC1

8.78e-051935448084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCellDendritic_Cells|World / lung cells shred on cell class, cell subclass, sample id

LPAR6 ENTPD1 MS4A6A FGL2

8.78e-051935447792eb6e247af2d7a8f80476f37dcd880922d625
ToppCellControl-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

CD55 MS4A6A AGTPBP1 FGL2

8.95e-05194544f852f5258617a66a4fbd56d64c7b47272e7b8b60
ToppCell368C-Myeloid-Dendritic-cDC2|368C / Donor, Lineage, Cell class and subclass (all cells)

LPAR6 ENTPD1 MS4A6A FGL2

8.95e-05194544eb9656d6d2da9aa074e6f5c06d750a6f9828208a
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|367C / Donor, Lineage, Cell class and subclass (all cells)

LPAR6 TLR7 MS4A6A FGL2

8.95e-05194544e3688f4252aae5f849f025d7f453ff4c0c14590b
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LPAR6 TLR7 MS4A6A FGL2

8.95e-051945448e2819a9d0529f7b2de1a7c1190575175d6173ee
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LPAR6 TLR7 MS4A6A FGL2

8.95e-05194544ad72be9f6871b334e1f477d868c15e7792fadea5
ToppCell343B-Myeloid-Dendritic-cDC2|343B / Donor, Lineage, Cell class and subclass (all cells)

ENTPD1 TLR7 MS4A6A FGL2

8.95e-05194544aa6c9b71006fd3863a802d112d9c3838865a52bf
ToppCellControl-Myeloid-MoAM4|Myeloid / Condition, Lineage and Cell class

LPAR6 ENTPD1 MS4A6A FGL2

8.95e-051945447ab808dd1876b0eec2831caa16d04fd859b1dc50
ToppCellILEUM-inflamed-(3)_moDC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

LPAR6 ENTPD1 MS4A6A FGL2

8.95e-05194544c9d2acab0bbcfa9a9113cf3b9f8147403f0beb43
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LPAR6 ENTPD1 MS4A6A FGL2

8.95e-05194544e56c6e5c9b7d287ae94566b561e21cec2055f83d
ToppCell368C-Myeloid-Dendritic|368C / Donor, Lineage, Cell class and subclass (all cells)

LPAR6 ENTPD1 MS4A6A FGL2

8.95e-051945444f88759d92ac229b1edd2d4b69b878bbf2d9b6bd
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

LPAR6 ENTPD1 MS4A6A FGL2

8.95e-0519454458046894446cb250814252a23f60fdd59c114d77
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LPAR6 ENTPD1 MS4A6A FGL2

8.95e-0519454444a90be1d2b2ae08f8c523bee65dd1e536ec0f95
ToppCelldroplet-Bladder-Unstain-18m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTMR7 ENTPD1 ADGRF5 FGL2

9.13e-05195544fbfe4a8ae9775764108b45920eec92003b24fb2e
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LPAR6 ENTPD1 MS4A6A FGL2

9.13e-051955449cfbdb528088ad0ab100c7431c7d8f140a846de8
ToppCellControl-Multiplet|Control / Disease state, Lineage and Cell class

ARHGEF12 ADGRF5 TANC1 AGBL1

9.13e-05195544618900c80bea09d46dad3f741bd1bff8bf0a64ee
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LPAR6 ENTPD1 MS4A6A FGL2

9.13e-0519554466f3b3e15eaa21bc7cf2f204cac81de1a160a748
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LPAR6 TLR7 MS4A6A FGL2

9.13e-05195544b6bf75669f267ecdc96818c7022db852e37a9fe1
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)-DC2_L.1.2.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LPAR6 ENTPD1 MS4A6A FGL2

9.13e-05195544bbf5f79be4fcea754328f1af7ee5625075248100
ToppCelldroplet-Bladder-Unstain-18m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTMR7 ENTPD1 ADGRF5 FGL2

9.13e-051955442a6056172c41c46acfe0242be22269ef1d07921e
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Dendritic_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

LPAR6 ENTPD1 MS4A6A FGL2

9.13e-05195544c12c73861f53e28f6e357001eccc1300db06e816
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LPAR6 ENTPD1 MS4A6A FGL2

9.13e-0519554485fee07d71c0393ea42bcf1130566dff4a62f507
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LPAR6 ENTPD1 MS4A6A FGL2

9.13e-051955447dd0cb8f3753fe761fac200cbd161708b6528c51
DiseaseLong Qt Syndrome 2

ALG10 ALG10B

9.13e-063522C3150943
Diseasenonsyndromic deafness (implicated_via_orthology)

ALG10 ALG10B

4.55e-056522DOID:0050563 (implicated_via_orthology)
Diseasemonocyte count

DPP4 TRPM7 ASH1L MED12L ARHGEF12 PSMD3 ADGRF5 ZFPM1 MS4A6A PTGFRN

8.82e-0513205210EFO_0005091
Diseasecardiac troponin I measurement

MBNL2 GREB1 ZFPM1 PTGFRN

2.65e-04176524EFO_0010071
Diseasealcohol dependence

MBNL2 ALG10 ADGRF5 ALG10B

3.07e-04183524MONDO_0007079
DiseaseOvarian Serous Adenocarcinoma

JAK2 TRPM7

7.53e-0423522C1335177
Diseaseasthma, cardiovascular disease

NEUROD2 PSMD3

1.28e-0330522EFO_0000319, MONDO_0004979
DiseaseParkinson disease

CCDC82 MBNL2 ASH1L MED12L

2.47e-03321524MONDO_0005180
Diseaseschizophrenia, type 2 diabetes mellitus

NEUROD2 PTGFRN

2.63e-0343522MONDO_0005090, MONDO_0005148
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

ASH1L TANC1

3.40e-0349522DOID:0060037 (implicated_via_orthology)
Diseaseplatelet-to-lymphocyte ratio

JAK2 MED12L PSMD3 ZFPM1

3.83e-03363524EFO_0008446
Diseasevascular endothelial growth factor measurement

ZNF462 ZFPM1

4.41e-0356522EFO_0004762

Protein segments in the cluster

PeptideGeneStartEntry
EYYSSCHKNRYAHPA

ERV3-1

141

Q14264
YICDYRLDKSAHLFY

ASH1L

2781

Q9NR48
CYLKAYHTNLYLSAD

NT5C1A

161

Q9BXI3
TYAHKYLLADNRHYT

ALG10B

341

Q5I7T1
GTDICYYKNHFSRSS

AGTPBP1

801

Q9UPW5
HEICYYKNHYRQSTA

AGBL1

686

Q96MI9
LLCYLYSDLYKHTNS

ARHGEF12

401

Q9NZN5
HSSLCKTYASFYEYK

NWD2

376

Q9ULI1
GYYRLTADAHHYLCK

JAK2

371

O60674
VHYYLYTSKLSFSSC

KCTD19

66

Q17RG1
YLYDLYVSCSHLRSK

MED12L

931

Q86YW9
RLSKYAAYNTYHHCE

GREB1

1456

Q4ZG55
LSYYYKDNHASICRS

MTMR7

191

Q9Y216
AACNHLRSYKYYTDS

PNLIP

276

P16233
KSTQPCEYYFRVYHS

COX6B2

51

Q6YFQ2
DHYGYRQSVTYACNK

CD55

241

P08174
FVACNHLRSYKYYLE

PNLIPRP1

276

P54315
RNEKCHDYYTTEFLY

PFKL

626

P17858
FSNVNNYYVHKRLYC

ZFPM1

586

Q8IX07
HSYTASYDIYDLNKR

DPP4

126

P27487
NIYCSRSKADYTSHL

GCN1

2176

Q92616
SSHCFYNDSFKYTLY

LPAR6

6

P43657
LYGKDYNVYTHSFLC

ENTPD1

241

P49961
SHYCLYSYRGSRLAQ

C17orf75

36

Q9HAS0
NAYSTREHTAYYIKA

UQCRC1

121

P31930
ELYYVNRDTLFCYHK

NAT10

506

Q9H0A0
AHLSYICRYDDKYSK

PGBD5

446

Q8N414
YAKYYFDLCALANDH

CCNYL3

176

P0C7X3
RYCKYSVHLSGELYN

CCDC82

431

Q8N4S0
HSTAYRFLSYNSAEC

CPHXL2

211

A0A1W2PPK0
YHDSLYTTDCYTAKA

MS4A6A

166

Q9H2W1
RDNSKYHCTAYRKFY

FCRL3

156

Q96P31
ESALRITKHCYCTYY

MBNL2

346

Q5VZF2
QHLIYKDCSDYYAIG

FGL2

206

Q14314
YLQVSSGCYKRHVYE

EML5

1836

Q05BV3
YKLRHLSYKSCESQY

EQTN

206

Q9NQ60
KHAYCSNLSFRLYDQ

CRLF1

376

O75462
RDVSKENSGYYYCHV

PTGFRN

361

Q9P2B2
FVKSQTTYYAQCYRH

SH3GLB2

256

Q9NR46
KYLASKVVAYHYCQA

TANC1

496

Q9C0D5
KVVAYHYCQADNTYT

TANC1

501

Q9C0D5
GTYHCIFRYKNSYSI

ADGRF5

541

Q8IZF2
TYAHKYLLADNRHYT

ALG10

341

Q5BKT4
QHSDSCYKLGAYYVT

COA7

66

Q96BR5
LAYYSSRQYASALKH

TTC30B

196

Q8N4P2
RALDLVAAKCYYYHA

PSMD3

201

O43242
KLFNELSYYTEHYRS

RBAK

546

Q9NYW8
EQLHYFRYDKYARSC

TLR7

461

Q9NYK1
YKRYVCSNSFSHNLY

ZNF112

471

Q9UJU3
LAYYSSRQYASALKH

TTC30A

196

Q86WT1
TELYYCKHCSYSNRS

ZNF462

1111

Q96JM2
YYCNRAAAQSKLGHY

SGTB

121

Q96EQ0
SHSYRAKYVRLSYDT

TRPM7

101

Q96QT4
HYCSYCGKTFRYSAN

ZNF34

251

Q8IZ26
YCEYRSADSSNLKTH

ZFY

576

P08048
RASFVSHYILQKYCS

UBASH3A

211

P57075
YCYICHSLKYDKLYS

MTNR1A

126

P48039
RTHGYCAAYETLYAA

NEUROD2

266

Q15784