Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	1-acylglycerol-3-phosphate O-acyltransferase activity	GPAT3 LCLAT1 GPAT2 TAFAZZIN	1.19e-05	21	138	4	GO:0003841
GeneOntologyMolecularFunction	lysophosphatidic acid acyltransferase activity	GPAT3 LCLAT1 GPAT2 TAFAZZIN	2.08e-05	24	138	4	GO:0042171
GeneOntologyMolecularFunction	lysophospholipid acyltransferase activity	GPAT3 LCLAT1 GPAT2 TAFAZZIN	2.08e-05	24	138	4	GO:0071617
GeneOntologyMolecularFunction	acylglycerol O-acyltransferase activity	GPAT3 LCLAT1 GPAT2 TAFAZZIN	6.76e-05	32	138	4	GO:0016411
GeneOntologyMolecularFunction	cargo receptor ligand activity	TCN2 HPSE	2.82e-04	4	138	2	GO:0140355
GeneOntologyMolecularFunction	glycerol-3-phosphate O-acyltransferase activity	GPAT3 GPAT2	4.68e-04	5	138	2	GO:0004366
Domain	WD40_repeat_dom	IFT140 POC1A ARPC1A EML2 PAAF1 WDFY4 ARPC1B WDR47 WDR11 ARHGEF10 PWP2 WDR17	1.98e-06	297	137	12	IPR017986
Domain	WD40	IFT140 POC1A ARPC1A EML2 PAAF1 WDFY4 ARPC1B WDR47 WDR11 PWP2 WDR17	3.35e-06	259	137	11	PF00400
Domain	WD40	IFT140 POC1A ARPC1A EML2 PAAF1 WDFY4 ARPC1B WDR47 WDR11 PWP2 WDR17	4.64e-06	268	137	11	SM00320
Domain	WD40_repeat	IFT140 POC1A ARPC1A EML2 PAAF1 WDFY4 ARPC1B WDR47 WDR11 PWP2 WDR17	5.35e-06	272	137	11	IPR001680
Domain	PlsC	GPAT3 LCLAT1 GPAT2 TAFAZZIN	6.12e-06	17	137	4	SM00563
Domain	Plipid/glycerol_acylTrfase	GPAT3 LCLAT1 GPAT2 TAFAZZIN	6.12e-06	17	137	4	IPR002123
Domain	WD_REPEATS_1	IFT140 POC1A ARPC1A EML2 PAAF1 WDFY4 ARPC1B WDR47 WDR11 PWP2 WDR17	6.58e-06	278	137	11	PS00678
Domain	WD_REPEATS_2	IFT140 POC1A ARPC1A EML2 PAAF1 WDFY4 ARPC1B WDR47 WDR11 PWP2 WDR17	6.81e-06	279	137	11	PS50082
Domain	WD_REPEATS_REGION	IFT140 POC1A ARPC1A EML2 PAAF1 WDFY4 ARPC1B WDR47 WDR11 PWP2 WDR17	6.81e-06	279	137	11	PS50294
Domain	WD40/YVTN_repeat-like_dom	IFT140 POC1A ARPC1A EML2 PAAF1 WDFY4 ARPC1B WDR47 WDR11 ARHGEF10 PWP2 WDR17	6.82e-06	335	137	12	IPR015943
Domain	-	IFT140 POC1A ARPC1A EML2 PAAF1 WDFY4 ARPC1B WDR47 WDR11 ARHGEF10 WDR17	3.52e-05	333	137	11	2.130.10.10
Domain	CARG-binding_factor_N	HNRNPAB HNRNPD	5.34e-05	2	137	2	IPR012956
Domain	CBFNT	HNRNPAB HNRNPD	5.34e-05	2	137	2	PF08143
Domain	ARPC1	ARPC1A ARPC1B	5.34e-05	2	137	2	IPR017383
Domain	Acyltransferase	GPAT3 LCLAT1 TAFAZZIN	2.02e-04	16	137	3	PF01553
Domain	WD40_repeat_CS	POC1A PAAF1 WDFY4 WDR47 WDR11 PWP2 WDR17	2.09e-04	164	137	7	IPR019775
Domain	Pept_S9_AS	APEH PREP	3.17e-04	4	137	2	IPR002471
Domain	PRO_ENDOPEP_SER	APEH PREP	5.26e-04	5	137	2	PS00708
Domain	PKD_2	PKDREJ PKD2	5.26e-04	5	137	2	IPR003915
Domain	Spectrin	SPTBN4 MACF1 MCF2L	6.14e-04	23	137	3	PF00435
Domain	Pentatricopeptide_repeat	IFT140 NCAPG2 PRORP	6.14e-04	23	137	3	IPR002885
Domain	Galactose-bd-like	EPHB3 DDR1 LAMB1 CUL9 EPHA1	6.42e-04	94	137	5	IPR008979
Domain	PKD/REJ-like	PKDREJ KIAA0319	7.86e-04	6	137	2	IPR002859
Domain	REJ	PKDREJ KIAA0319	7.86e-04	6	137	2	PF02010
Domain	PH_dom-like	RANBP2 PLEKHG4 AGAP11 WDFY4 TYK2 SPTBN4 MTMR7 ARHGEF10 MCF2L ARAP1	1.20e-03	426	137	10	IPR011993
Domain	Spectrin_repeat	SPTBN4 MACF1 MCF2L	1.23e-03	29	137	3	IPR002017
Domain	DHC_N1	DNAH8 DNAH9	1.45e-03	8	137	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH8 DNAH9	1.45e-03	8	137	2	IPR013594
Domain	SAM_1	EPHB3 SASH1 ARAP1 EPHA1	1.57e-03	68	137	4	PF00536
Domain	SPEC	SPTBN4 MACF1 MCF2L	1.64e-03	32	137	3	SM00150
Domain	Spectrin/alpha-actinin	SPTBN4 MACF1 MCF2L	1.64e-03	32	137	3	IPR018159
Domain	-	EPHB3 DDR1 CUL9 EPHA1	2.04e-03	73	137	4	2.60.120.260
Domain	Peptidase_S9	APEH PREP	2.81e-03	11	137	2	PF00326
Domain	PKD_channel	PKDREJ PKD2	2.81e-03	11	137	2	PF08016
Domain	Peptidase_S9	APEH PREP	2.81e-03	11	137	2	IPR001375
Domain	PKD1_2_channel	PKDREJ PKD2	2.81e-03	11	137	2	IPR013122
Domain	GDS_CDC24_CS	PLEKHG4 ARHGEF10 MCF2L	2.91e-03	39	137	3	IPR001331
Domain	G-protein_beta_WD-40_rep	POC1A PAAF1 PWP2 WDR17	3.54e-03	85	137	4	IPR020472
Domain	ARM-type_fold	WAPL CUL9 CTIF HUWE1 WDFY4 NCAPG2 GCN1 AGBL1	3.58e-03	339	137	8	IPR016024
Domain	Tyr_kinase_cat_dom	EPHB3 DDR1 TYK2 EPHA1	4.01e-03	88	137	4	IPR020635
Domain	TyrKc	EPHB3 DDR1 TYK2 EPHA1	4.01e-03	88	137	4	SM00219
Domain	SAM	EPHB3 SASH1 ARAP1 EPHA1	4.01e-03	88	137	4	SM00454
Domain	RECEPTOR_TYR_KIN_V_2	EPHB3 EPHA1	4.59e-03	14	137	2	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHB3 EPHA1	4.59e-03	14	137	2	PS00790
Domain	Dynein_heavy_chain_D4_dom	DNAH8 DNAH9	4.59e-03	14	137	2	IPR024317
Domain	Tyr_kinase_rcpt_V_CS	EPHB3 EPHA1	4.59e-03	14	137	2	IPR001426
Domain	Dynein_HC_stalk	DNAH8 DNAH9	4.59e-03	14	137	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH8 DNAH9	4.59e-03	14	137	2	IPR013602
Domain	DHC_N2	DNAH8 DNAH9	4.59e-03	14	137	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH8 DNAH9	4.59e-03	14	137	2	IPR011704
Domain	EphA2_TM	EPHB3 EPHA1	4.59e-03	14	137	2	PF14575
Domain	Ephrin_rcpt_lig-bd_dom	EPHB3 EPHA1	4.59e-03	14	137	2	IPR001090
Domain	Eph_TM	EPHB3 EPHA1	4.59e-03	14	137	2	IPR027936
Domain	EPH_lbd	EPHB3 EPHA1	4.59e-03	14	137	2	SM00615
Domain	Ephrin_lbd	EPHB3 EPHA1	4.59e-03	14	137	2	PF01404
Domain	MT	DNAH8 DNAH9	4.59e-03	14	137	2	PF12777
Domain	AAA_8	DNAH8 DNAH9	4.59e-03	14	137	2	PF12780
Domain	Tyr_kinase_ephrin_rcpt	EPHB3 EPHA1	4.59e-03	14	137	2	IPR016257
Domain	EPH_LBD	EPHB3 EPHA1	4.59e-03	14	137	2	PS51550
Domain	AAA_5	DNAH8 DNAH9	4.59e-03	14	137	2	PF07728
Domain	-	PIWIL2 ERI1 REV3L	4.95e-03	47	137	3	3.30.420.10
Domain	DHC_fam	DNAH8 DNAH9	5.27e-03	15	137	2	IPR026983
Domain	Dynein_heavy	DNAH8 DNAH9	5.27e-03	15	137	2	PF03028
Domain	Dynein_heavy_dom	DNAH8 DNAH9	5.27e-03	15	137	2	IPR004273
Domain	SAM_DOMAIN	EPHB3 SASH1 ARAP1 EPHA1	5.27e-03	95	137	4	PS50105
Domain	PROTEIN_KINASE_TYR	EPHB3 DDR1 TYK2 EPHA1	5.67e-03	97	137	4	PS00109
Domain	SAM	EPHB3 SASH1 ARAP1 EPHA1	5.67e-03	97	137	4	IPR001660
Domain	Tyr_kinase_AS	EPHB3 DDR1 TYK2 EPHA1	5.67e-03	97	137	4	IPR008266
Domain	ATPase_P-typ_cation-transptr_C	ATP13A3 ATP1A4	6.76e-03	17	137	2	IPR006068
Domain	Cation_ATPase_C	ATP13A3 ATP1A4	6.76e-03	17	137	2	PF00689
Domain	Quinoprotein_ADH-like_supfam	EML2 PWP2 WDR17	6.92e-03	53	137	3	IPR011047
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	GPC1 RANBP2 WAPL NUP107 PLEKHG4 BMS1 ERI1 HUWE1 AGPS NCAPH NCAPG2 HNRNPAB ARPC1B HNRNPD WDR47 DECR1 FASN WDR11 MACF1 GCN1 TOP2B PCID2	2.93e-08	1353	141	22	29467282
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	TANC2 RANBP2 SHROOM3 WAPL NUP107 HUWE1 NCAPH HNRNPAB HNRNPD FASN TOX4 MACF1 GCN1 ARAP1	1.19e-07	582	141	14	20467437
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	HUWE1 KIAA0319 ARHGEF10 PRORP MCF2L DNAH9	4.37e-06	104	141	6	9205841
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CNTN4 WAPL ZNF473 TTLL5 APEH LAMB1 CUL9 SPOCK2 HUWE1 REV3L ADD3 WDR47 SPTBN4 DNAJC14 ARHGEF10 MACF1 QTRT1 WDR17	4.87e-06	1285	141	18	35914814
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	RANBP2 WAPL ACOT9 BMS1 ERI1 HUWE1 AGPS NCAPH HNRNPAB ARPC1B HNRNPD DECR1 FASN TOX4 PWP2 GCN1 TOP2B PCID2	6.88e-06	1318	141	18	30463901
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	IFT140 SHROOM3 WAPL SASH1 BMS1 AGAP11 NCAPH CAMKK2 LHFPL2 CACNA1G ARAP1	1.13e-05	529	141	11	14621295
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TANC2 SHROOM3 APEH CUL9 EML2 IRF5 HUWE1 REV3L ACOX3 TYK2 FASN DNAJC14 MCF2L GCN1 PLK3 ARAP1	1.13e-05	1105	141	16	35748872
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	IFT140 CUL9 SPOCK2 KIAA0319 SPTBN4 MACF1	1.58e-05	130	141	6	12421765
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	RANBP2 WAPL HNRNPAB HNRNPD TOX4 ATP1A4 GCN1 TOP2B	1.59e-05	271	141	8	32433965
Pubmed	Lack of interaction between systemic lupus erythematosus-associated polymorphisms in TYK2 and IRF5.	IRF5 TYK2	1.63e-05	2	141	2	20197570
Pubmed	γ-Adducin stimulates the thiazide-sensitive NaCl cotransporter.	ADD3 SLC12A3	1.63e-05	2	141	2	21164023
Pubmed	Association of common variation in ADD3 and GPC1 with biliary atresia susceptibility.	GPC1 ADD3	1.63e-05	2	141	2	32315284
Pubmed	Evidence for genetic association and interaction between the TYK2 and IRF5 genes in systemic lupus erythematosus.	IRF5 TYK2	1.63e-05	2	141	2	19567624
Pubmed	Genetic association and interaction between the IRF5 and TYK2 genes and systemic lupus erythematosus in the Han Chinese population.	IRF5 TYK2	1.63e-05	2	141	2	26294277
Pubmed	Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis.	IRF5 TYK2	1.63e-05	2	141	2	17599733
Pubmed	Polymorphisms in IRF5 and TYK2 Genes Are Associated with Rheumatoid Arthritis in a Chinese Han Population.	IRF5 TYK2	1.63e-05	2	141	2	33583939
Pubmed	Impaired glutamylation of RPGRORF15 underlies the cone-dominated phenotype associated with truncating distal ORF15 variants.	TTLL5 RPGR	1.63e-05	2	141	2	36445968
Pubmed	GPAT2, a mitochondrial outer membrane protein, in piRNA biogenesis in germline stem cells.	PIWIL2 GPAT2	1.63e-05	2	141	2	23611983
Pubmed	The sodium/proton exchanger NHA2 regulates blood pressure through a WNK4-NCC dependent pathway in the kidney.	SLC12A3 SLC9B2	1.63e-05	2	141	2	32956652
Pubmed	Soluble (Pro)Renin Receptor as a Negative Regulator of NCC (Na+-Cl- Cotransporter) Activity.	SLC12A3 ATP6AP2	1.63e-05	2	141	2	34495675
Pubmed	Cytosolic Pellino-1-Mediated K63-Linked Ubiquitination of IRF5 in M1 Macrophages Regulates Glucose Intolerance in Obesity.	PELI1 IRF5	1.63e-05	2	141	2	28746869
Pubmed	Defining the membrane proteome of NK cells.	RANBP2 NUP107 HUWE1 AGPS NCAPH NCAPG2 LCLAT1 ACOX3 FASN DNAJC14 WDR11 PREP ATP13A3 GOLGA5 GCN1 RUSF1	2.23e-05	1168	141	16	19946888
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	RANBP2 COG7 BMS1 LAMB1 HUWE1 NCAPH HPSE NCAPG2 HNRNPAB ARPC1B HNRNPD LCLAT1 DECR1 FASN COMMD7 ATP13A3 GCN1 TOP2B	2.25e-05	1440	141	18	30833792
Pubmed	Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.	WAPL SPOCK2 SLC35D1 LHFPL2 GCN1	2.30e-05	83	141	5	9039502
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	RANBP2 HUWE1 AGPS NCAPH NCAPG2 ARPC1B HNRNPD FASN DNAH8 GCN1 TOP2B LCMT1	3.19e-05	704	141	12	29955894
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SHROOM3 NUP107 TTLL5 BMS1 GPAT3 APEH LAMB1 NCAPG2 ADD3 CAMKK2 DNAJC14 WDR11 ARHGEF10 ATP6AP2 PWP2 MACF1 GOLGA5 TOP2B	3.43e-05	1487	141	18	33957083
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TANC2 CNTN4 ZNF473 CTIF WDFY4 TOX4 WDR11 MACF1 ARHGAP28 PRORP	3.53e-05	493	141	10	15368895
Pubmed	Tyrosine kinase 2 and interferon regulatory factor 5 polymorphisms are associated with discoid and subacute cutaneous lupus erythematosus.	IRF5 TYK2	4.88e-05	3	141	2	19758313
Pubmed	Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.	IRF5 TYK2	4.88e-05	3	141	2	15657875
Pubmed	MACF1 links Rapsyn to microtubule- and actin-binding proteins to maintain neuromuscular synapses.	MACF1 TOP2B	4.88e-05	3	141	2	30842214
Pubmed	Loss of RPGR glutamylation underlies the pathogenic mechanism of retinal dystrophy caused by TTLL5 mutations.	TTLL5 RPGR	4.88e-05	3	141	2	27162334
Pubmed	Nodal β spectrins are required to maintain Na+ channel clustering and axon integrity.	SPTBN4 AVIL	4.88e-05	3	141	2	32052742
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	MBTD1 RANBP2 WAPL NUP107 PLEKHG4 BMS1 CUL9 HUWE1 REV3L NCAPH WDR47 FASN TOP2B	4.92e-05	857	141	13	25609649
Pubmed	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	IRF5 WDFY4 SLC15A4	5.09e-05	18	141	3	19838193
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SASH1 CAMKK2 TOX4 MACF1 ARAP1	5.91e-05	101	141	5	9872452
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	RANBP2 NUP107 COG7 HUWE1 HNRNPAB HNRNPD ADD3 FASN PWP2 GCN1 TOP2B	6.21e-05	638	141	11	33239621
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	ZCCHC9 BMS1 ERI1 HNRNPAB HNRNPD DECR1 TOX4 PWP2 MACF1 GCN1 TOP2B PCID2	6.56e-05	759	141	12	35915203
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	RANBP2 WAPL POC1A NUP107 COG7 ACOT9 LAMB1 HNRNPAB HNRNPD DECR1 FASN TOX4 GCN1 TOP2B ARAP1	7.44e-05	1155	141	15	20360068
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	RANBP2 HMGB2 NCAPH HNRNPAB HNRNPD SPTBN4 FASN AVIL PWP2 MACF1 MYOM2 MCF2L ATP1A4 DNAH8 TOP2B PCID2 LCMT1	7.94e-05	1442	141	17	35575683
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SHROOM3 NUP107 BMS1 APEH HUWE1 AGPS NCAPH ADD3 WDR11 RPGR GOLGA5 GCN1	8.18e-05	777	141	12	35844135
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	GPC1 COG7 ARPC1A APEH LAMB1 HMGB2 ERI1 HUWE1 PAAF1 NCAPH HNRNPAB ARPC1B HNRNPD FASN ARHGEF10 MACF1 GCN1	8.85e-05	1455	141	17	22863883
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	TANC2 ZCCHC9 PLEKHG4 ACOT9 HMGB2 HUWE1 ARPC1B TOX4 ARHGEF10 ARHGAP28 MCF2L GCN1 ARAP1	9.60e-05	916	141	13	32203420
Pubmed	Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation.	EPHB3 HUWE1	9.74e-05	4	141	2	27184401
Pubmed	Axon Initial Segments Are Required for Efficient Motor Neuron Axon Regeneration and Functional Recovery of Synapses.	SPTBN4 AVIL	9.74e-05	4	141	2	36096668
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	EPHB3 DDR1 PLEKHG4 COG7 HUWE1 NCOA4 NCAPG2 LCLAT1 KIAA0319 SLC15A4 MACF1 ATP13A3 GOLGA5 RUSF1	1.11e-04	1061	141	14	33845483
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	RANBP2 WAPL NUP107 FASN PWP2 GCN1 TOP2B	1.28e-04	272	141	7	31010829
Pubmed	Functional consequences of necdin nucleocytoplasmic localization.	LAMB1 HUWE1 NCOA4 NCAPH	1.36e-04	64	141	4	22442722
Pubmed	Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.	EPHB3 TYK2 EPHA1	1.41e-04	25	141	3	15254900
Pubmed	Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution.	SASH1 CUL9 RPGR MCF2L	1.53e-04	66	141	4	15790807
Pubmed	Polycystin channels and kidney disease.	PKDREJ PKD2	1.62e-04	5	141	2	11698076
Pubmed	Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program.	MLYCD FASN	1.62e-04	5	141	2	37163372
Pubmed	Transforming Growth Factor-β1 Promotes M1 Alveolar Macrophage Polarization in Acute Lung Injury by Up-Regulating DNMT1 to Mediate the microRNA-124/PELI1/IRF5 Axis.	PELI1 IRF5	1.62e-04	5	141	2	34504806
Pubmed	RanGTP mediates nuclear pore complex assembly.	RANBP2 NUP107	1.62e-04	5	141	2	12894213
Pubmed	Folic acid supplementation can adversely affect murine neural tube closure and embryonic survival.	SHROOM3 FREM2	1.62e-04	5	141	2	21693562
Pubmed	TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.	IRF5 SLC15A4	1.62e-04	5	141	2	32433612
Pubmed	Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin.	RPGR INVS	1.62e-04	5	141	2	15723066
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	RANBP2 BMS1 LAMB1 HUWE1 PAAF1 NCAPG2 TYK2 FASN MTMR7 PREP ATP6AP2 PRORP GCN1	1.76e-04	974	141	13	28675297
Pubmed	Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation.	NUP107 HUWE1 FASN GCN1	2.15e-04	72	141	4	36376293
Pubmed	Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity.	WAPL TOP2B	2.42e-04	6	141	2	31202577
Pubmed	Genome-wide association study does not reveal major genetic determinants for anti-cytomegalovirus antibody response.	FREM2 AGBL1	2.42e-04	6	141	2	21993531
Pubmed	A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.	RANBP2 PELI1 NCAPG2 PDPN FREM2 ATP6AP2 DNAH8	2.43e-04	302	141	7	30561431
Pubmed	Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro.	SHROOM3 ADD3 LHFPL2	2.44e-04	30	141	3	29555813
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	SHROOM3 WAPL NUP107 LAMB1 NCAPH HNRNPAB HNRNPD FASN CACNA1G GOLGA5 PCID2	2.66e-04	754	141	11	35906200
Pubmed	Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.	LAMB1 NCAPH HNRNPAB HNRNPD FREM2 GCN1	2.81e-04	219	141	6	31353912
Pubmed	Interaction proteomics of the HMGA chromatin architectural factors.	HMGB2 HNRNPAB HNRNPD	2.97e-04	32	141	3	18850631
Pubmed	The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis.	HNRNPAB HNRNPD PDPN	2.97e-04	32	141	3	28546511
Pubmed	Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.	HUWE1 AGPS ARPC1B FAH MACF1	3.02e-04	143	141	5	30397336
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CAMKK2 ARHGEF10 MACF1 CACNA1G GCN1 ARAP1	3.25e-04	225	141	6	12168954
Pubmed	GPAT2 is required for piRNA biogenesis, transposon silencing, and maintenance of spermatogonia in mice†.	PIWIL2 GPAT2	3.38e-04	7	141	2	30951587
Pubmed	Polycystic Kidney Disease, Autosomal Dominant	IFT140 PKD2	3.38e-04	7	141	2	20301424
Pubmed	Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia.	DDR1 TYK2	3.38e-04	7	141	2	18270328
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH8 DNAH9	3.38e-04	7	141	2	31178125
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RANBP2 NUP107 BMS1 CUL9 HUWE1 FASN PREP PWP2 MACF1 GCN1	3.47e-04	653	141	10	22586326
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	RANBP2 NUP107 BMS1 LAMB1 HUWE1 HNRNPAB HNRNPD FASN ATP6AP2 GCN1	3.64e-04	657	141	10	36180527
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	GPC1 TANC2 RANBP2 SASH1 HNRNPD MACF1	3.74e-04	231	141	6	16452087
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	GPC1 RANBP2 NUP107 ARPC1A HNRNPAB ARPC1B DECR1 MACF1 TOP2B PCID2	3.78e-04	660	141	10	32780723
Pubmed	Genome-wide association study of selenium concentrations.	ARHGEF10 LHFPL2 MYOM2	3.88e-04	35	141	3	25343990
Pubmed	Nsp2 has the potential to be a drug target revealed by global identification of SARS-CoV-2 Nsp2-interacting proteins.	WAPL NUP107 GCN1 ARAP1	3.88e-04	84	141	4	34159380
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	GPC1 RANBP2 ZNF473 NUP107 GPAT3 AGPS HNRNPD LCLAT1 FASN ATP6AP2 GOLGA5 RUSF1 TOP2B PCID2	3.98e-04	1203	141	14	29180619
Pubmed	Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model.	SLC12A3 PKD2 INVS	4.22e-04	36	141	3	33737325
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	RANBP2 WAPL NUP107 NCAPH HNRNPAB ADD3 FASN TOX4 MACF1 GOLGA5 GCN1 TOP2B	4.41e-04	934	141	12	33916271
Pubmed	Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells.	NCAPH NCAPG2	4.50e-04	8	141	2	14532007
Pubmed	The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.	ARPC1A ARPC1B	4.50e-04	8	141	2	9230079
Pubmed	Reconstitution and subunit geometry of human condensin complexes.	NCAPH NCAPG2	4.50e-04	8	141	2	17268547
Pubmed	Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins.	ARPC1A ARPC1B	4.50e-04	8	141	2	9359840
Pubmed	Eph:ephrin-B1 forward signaling controls fasciculation of sensory and motor axons.	EPHB3 EPHA1	4.50e-04	8	141	2	24056079
Pubmed	Gradual differentiation and confinement of the cardiac conduction system as indicated by marker gene expression.	EPHB3 CACNA1G	4.50e-04	8	141	2	31306714
Pubmed	Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisions.	NCAPH NCAPG2	4.50e-04	8	141	2	25474630
Pubmed	Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.	IRF5 WDFY4 SLC15A4	4.96e-04	38	141	3	23273568
Pubmed	ARAP1 association with CIN85 affects epidermal growth factor receptor endocytic trafficking.	WAPL ARAP1	5.77e-04	9	141	2	21275903
Pubmed	Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.	RANBP2 TOP2B	5.77e-04	9	141	2	18394993
Pubmed	Chromosomal mapping of the psychomotor stimulant effects of cocaine in BXD recombinant inbred mice.	CHRNA3 OPCML	5.77e-04	9	141	2	8748389
Pubmed	Polycystic kidneys caused by sustained expression of Cux1 isoform p75.	PKD2 INVS	5.77e-04	9	141	2	18356167
Pubmed	Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.	EPHB3 DDR1 EPHA1	5.77e-04	40	141	3	30898150
Pubmed	WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.	IFT140 ARPC1B WDR47	5.77e-04	40	141	3	29078390
Pubmed	Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development.	IFT140 PDPN DNAH9	5.77e-04	40	141	3	32317081
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	GPC1 NUP107 ACOT9 BMS1 TEAD4 LCLAT1 PRORP GOLGA5	5.78e-04	457	141	8	32344865
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	GPC1 ACOT9 ARPC1A BMS1 HMGB2 NCAPH HNRNPAB ARPC1B HNRNPD ADD3 DECR1 FASN WDR11 PWP2	6.13e-04	1257	141	14	36526897
Pubmed	Human variation in alcohol response is influenced by variation in neuronal signaling genes.	CNTN4 LAMB1 CHRNA3 FAH TOP2B	6.84e-04	171	141	5	20201926
Pubmed	Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion.	ARPC1A ARPC1B	7.19e-04	10	141	2	12473693
Cytoband	6q22	MFSD4B PREP	2.59e-04	8	141	2	6q22
Cytoband	2p22-p21	THUMPD2 NLRC4	2.59e-04	8	141	2	2p22-p21
Cytoband	1p32-p31	SLC35D1 MACF1	3.32e-04	9	141	2	1p32-p31
Cytoband	Ensembl 112 genes in cytogenetic band chr4q21	SHROOM3 GPAT3 HPSE HNRNPD	7.82e-04	133	141	4	chr4q21
Cytoband	12q24.2	CAMKK2 GCN1	1.09e-03	16	141	2	12q24.2
Cytoband	10q23.2	WAPL AGAP11	1.24e-03	17	141	2	10q23.2
GeneFamily	WD repeat domain containing	IFT140 POC1A ARPC1A EML2 PAAF1 WDFY4 ARPC1B WDR47 WDR11 PWP2 WDR17	6.46e-08	262	89	11	362
GeneFamily	Glycerol-3-phosphate acyltransferases	GPAT3 GPAT2	1.43e-04	4	89	2	1035
GeneFamily	Actin related protein 2/3 complex	ARPC1A ARPC1B	8.43e-04	9	89	2	39
GeneFamily	Sterile alpha motif domain containing	EPHB3 SASH1 ARAP1 EPHA1	9.34e-04	88	89	4	760
GeneFamily	1-acylglycerol-3-phosphate O-acyltransferases	GPAT3 LCLAT1	1.28e-03	11	89	2	46
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHB3 EPHA1	2.10e-03	14	89	2	1095
GeneFamily	Dyneins, axonemal	DNAH8 DNAH9	3.11e-03	17	89	2	536
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHG4 ARHGEF10 MCF2L	4.22e-03	66	89	3	722
Coexpression	GSE19772_CTRL_VS_HCMV_INF_MONOCYTES_UP	TCN2 IRF5 LCLAT1 CD160 SLC35D1 DECR1 FAH INVS	1.26e-05	200	140	8	M7282
Coexpression	GSE5589_WT_VS_IL10_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN	PKDREJ THUMPD2 MLYCD WDR47 TOX4 ARHGEF10 COMMD7 PRORP	1.26e-05	200	140	8	M6652
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPC1 PLCXD2 NCAPH CD160 MLYCD WDR47 TYK2	1.35e-06	173	141	7	b6bb2a136a40f0946bbcde8d5972d3f059d080c7
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTN4 SHROOM3 PLCXD2 SPOCK2 PDPN MTMR7 OSGIN1	1.69e-06	179	141	7	d5e3e7f1cd8f683f39a7416f12af7e766dcbead8
ToppCell	tumor_Lung-T/NK_cells-Treg\|T/NK_cells / Location, Cell class and cell subclass	ACOT9 ICAM3 CUL9 PELI1 SPOCK2 ARPC1B IFI6	2.99e-06	195	141	7	dd112ef3f8bd0790719827b6bb120918687afdff
ToppCell	facs-Bladder-nan-3m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB1 REV3L ADD3 PKD2 MACF1 TOP2B ARAP1	3.09e-06	196	141	7	44f5b1b474399c9316729155f2ea95a82ca66e30
ToppCell	facs-Bladder-nan-3m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB1 REV3L ADD3 PKD2 MACF1 TOP2B ARAP1	3.09e-06	196	141	7	c0e90d964baa2eb4fbd18a52379ccec5d3bf59a8
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CNTN4 LAMB1 COL6A5 REV3L PDPN FASN ATP13A3	3.41e-06	199	141	7	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TOPAZ1 OPCML SPATA16 VRTN DNAH8 AGBL1	8.40e-06	150	141	6	0205318a870e091add66ee4305747dda9f51510d
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTN4 COL6A5 TEAD4 GPX6 WDR17 DNAH9	1.21e-05	160	141	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTN4 COL6A5 TEAD4 GPX6 WDR17 DNAH9	1.21e-05	160	141	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	P28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GPC1 DDR1 POC1A HPSE PDPN FAH	1.60e-05	168	141	6	8c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COG7 SLC35D1 DECR1 FREM2 PRORP PRODH	1.95e-05	174	141	6	c58328c2f262506a4518f49f148e29874faf9171
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Spp1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ZNF473 PLEKHG4 PKDREJ DNAH9	2.59e-05	54	141	4	98b31718fa200432cf86b59a52484da101219f96
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Spp1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ZNF473 PLEKHG4 PKDREJ DNAH9	2.59e-05	54	141	4	872e7374dac64be2c8ebe71e88a2ec6814168d89
ToppCell	droplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TANC2 GPAT3 NCOA4 MTMR7 LHFPL2 ATP13A3	2.67e-05	184	141	6	15ea746c77785120f69f9ab370fb7eb9b70692f8
ToppCell	droplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TANC2 GPAT3 NCOA4 MTMR7 LHFPL2 ATP13A3	2.67e-05	184	141	6	bd5e8fc453a6393b8778734a2c3c2f1281769bcd
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOT9 CASTOR2 TEAD4 RTN2 ADD3 LHFPL2	2.76e-05	185	141	6	efcfbf5a48b3ea9a425183e5c2eec6a9585415a0
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOT9 CASTOR2 TEAD4 RTN2 ADD3 LHFPL2	2.76e-05	185	141	6	642088ace9230d38b0579853c54ff4dd8b5d5df4
ToppCell	IPF-Lymphoid-T_Regulatory\|Lymphoid / Disease state, Lineage and Cell class	ACOT9 CUL9 PELI1 SPOCK2 ERI1 ATP13A3	3.11e-05	189	141	6	7a260485c2a7c743c14d048e5e480ae0a9b8e32c
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CNTN4 HMGB2 CASTOR2 REV3L NCAPH NCAPG2	3.60e-05	194	141	6	7a66bd7d4fc9c6db861cedd2487f241e406869d1
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ICAM3 CUL9 PELI1 SPOCK2 ARPC1B DNAH8	3.92e-05	197	141	6	54fb7197db3c0dc87a1114e1ab1d2bfafd564b35
ToppCell	PBMC\|World / Compartment, Disease Groups and Clusters	ARPC1A ICAM3 HMGB2 ARPC1B HNRNPD COMMD7	4.03e-05	198	141	6	84f5b43dad0c57556171dbc0b799735654582ecf
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ICAM3 CUL9 PELI1 SPOCK2 ARPC1B DNAH8	4.03e-05	198	141	6	03423d6c614440b9c738f75ac3f5a6941719a279
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CNTN4 LAMB1 COL6A5 REV3L PDPN MACF1	4.14e-05	199	141	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GPC1 DDR1 LAMB1 ERI1 ATP6AP2 PKD2	4.14e-05	199	141	6	174f6013af6eafa577f84205a62927f2b367fda3
Disease	protrudin measurement	HPSE GOLGA5	2.18e-04	5	139	2	EFO_0802976
Disease	autosomal dominant limb-girdle muscular dystrophy type 3 (implicated_via_orthology)	HNRNPAB HNRNPD	3.26e-04	6	139	2	DOID:0110306 (implicated_via_orthology)
Disease	Lissencephaly	LAMB1 MACF1	3.26e-04	6	139	2	C0266463
Disease	syndromic X-linked intellectual disability (implicated_via_orthology)	HUWE1 ATP6AP2	6.06e-04	8	139	2	DOID:0060309 (implicated_via_orthology)
Disease	psoriatic arthritis	DDR1 REV3L MFSD4B TYK2	7.75e-04	87	139	4	EFO_0003778
Disease	cerebral palsy (implicated_via_orthology)	AGAP11 ADD3	9.67e-04	10	139	2	DOID:1969 (implicated_via_orthology)
Disease	Paranoia	TYK2 DNAH8	1.18e-03	11	139	2	C1456784
Disease	response to virus	FREM2 AGBL1	1.18e-03	11	139	2	GO_0009615
Disease	Primary biliary cirrhosis	ICAM3 IRF5 TYK2	1.43e-03	47	139	3	C0008312
Disease	Erythrocyte Mean Corpuscular Hemoglobin Test	MLYCD FAH	1.66e-03	13	139	2	C0369183
Disease	Finding of Mean Corpuscular Hemoglobin	MLYCD FAH	1.66e-03	13	139	2	C1261502
Disease	C-reactive protein measurement	EML2 IRF5 ERI1 MFSD4B MLYCD CAMKK2 SPATA16 GYS2 MACF1 PRORP GCN1 TOP2B ARAP1 OSGIN1	1.71e-03	1206	139	14	EFO_0004458
Disease	Ciliopathies	PKD2 RPGR DNAH8 INVS	1.85e-03	110	139	4	C4277690
Disease	psoriasis	DDR1 REV3L MFSD4B TYK2 PRORP QTRT1	1.91e-03	273	139	6	EFO_0000676
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	PKD2 KIF28P	1.93e-03	14	139	2	DOID:898 (implicated_via_orthology)
Disease	Situs ambiguus	SHROOM3 DNAH9	2.22e-03	15	139	2	C0266642
Disease	testosterone measurement	DDR1 SHROOM3 PKDREJ SLC22A7 NLRC4 LCLAT1 MLYCD TYK2 FASN WDR11 LHFPL2 MACF1 ARAP1 OSGIN1	2.84e-03	1275	139	14	EFO_0004908
Disease	Vascular Diseases	SLC12A3 PKD2	2.86e-03	17	139	2	C0042373
Disease	parahippocampal gyrus volume measurement	EPHB3 FREM2	3.21e-03	18	139	2	EFO_0010318
Disease	rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement	IRF5 WDFY4 TYK2	3.30e-03	63	139	3	EFO_0000685, EFO_0007791, EFO_0009459
Disease	rheumatoid arthritis, COVID-19	IRF5 TYK2 GPX6	3.46e-03	64	139	3	EFO_0000685, MONDO_0100096
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	CYP8B1 MLYCD FASN	3.61e-03	65	139	3	DOID:0080208 (biomarker_via_orthology)
Disease	primary biliary cirrhosis	IRF5 WDFY4 TYK2 PRORP	3.67e-03	133	139	4	EFO_1001486
Disease	unipolar depression, memory performance, cognitive function measurement	CNTN4 KIAA0319	3.96e-03	20	139	2	EFO_0003761, EFO_0004874, EFO_0008354
Disease	coagulation factor measurement	MCF2L PCID2	3.96e-03	20	139	2	EFO_0004634
Disease	rheumatoid arthritis, ulcerative colitis	APEH TYK2	4.36e-03	21	139	2	EFO_0000685, EFO_0000729
Disease	Neutropenia	TPMT TCN2	4.36e-03	21	139	2	C0027947
Disease	prothrombin time measurement	MCF2L PCID2	4.36e-03	21	139	2	EFO_0008390

Protein segments in the cluster

Peptide	Gene	Start	Entry
SLLTDGSWDMSKFLN	ERI1	226	Q8IV48
MDTSKAQGELGWLLD	EPHA1	31	P21709
SFGIVMWEVLSFGDK	EPHA1	811	P21709
IWLGDSLGSMTQKSD	ARHGEF10	1266	O15013
WSVKDQTMGLGKTFS	AVIL	346	O75366
LISKMDSWNTAGIGE	COG7	596	P83436
SMGWSNLFTSEKGSD	AGAP11	86	Q8TF27
GSKDNSLDMLGTDIW	CTIF	86	O43310
SWKELALFTEGEGML	ACOX3	31	O15254
LIGSSMNLKDYWESG	CHRNA3	191	P32297
ITWMKAEDSSKVSGG	ADD3	466	Q9UEY8
GTLSSGFLQEKVWVM	CD160	156	O95971
SGDPLDLKMFEAIGW	ATP13A3	556	Q9H7F0
DGGMSIWDVKSLESA	ARPC1B	351	O15143
LMGKFTTASDVWAFG	DDR1	816	Q08345
DMLIFGSLTAWFLKE	GYS2	151	P54840
FTSASGELWKMVRIG	CASTOR2	256	A6NHX0
RWKLNGTDVDTGMDF	CNTN4	61	Q8IWV2
KFSGHVSWVGKTSME	ACOT9	166	Q9Y305
GVKGWLTMSSLFNKE	C1orf232	61	A0A0U1RR37
PLSKTGSGFMWVDDI	CD163L1	1196	Q9NR16
GEKDTWSGMRTTGQL	BMS1	1121	Q14692
GESNASWVMKGTLEF	AGBL1	806	Q96MI9
TGIDGAMTIWDFKTL	ARPC1A	346	Q92747
MWLASDFSDGDAKLE	RANBP2	2106	P49792
LDEAMGSSEWLALTK	RLN3	81	Q8WXF3
LGDIDGLMDEFSKWL	NUP107	521	P57740
FASGGSDEQVMVWKS	POC1A	286	Q8NBT0
GDFWAESSMLGLKIT	DNAJC14	571	Q6Y2X3
SDGWLAFMGVFENLK	NLRC4	951	Q9NPP4
KTKAAVSMEGFSWGN	MBTD1	131	Q05BQ5
ELKSPSMSDFLWGLE	MTMR7	291	Q9Y216
SMVLITDKFWGTSGV	GPC1	296	P35052
SIGDTAKKLGEMWSE	HMGB2	121	P26583
MSWFVDLAGKAEDLL	GOLGA5	1	Q8TBA6
LSKKSLWLSDGSMGF	FREM2	2866	Q5SZK8
QDSKSFGIMVSWKGI	LCLAT1	31	Q6UWP7
VLKGMLSEWFSSGFL	MLYCD	181	O95822
ESLKLMSATGFLWSL	DNAH8	3216	Q96JB1
GMWIKEDLDSLVFGI	MACF1	1366	O94854
EAMGLFTKWSRSLGF	LCN6	146	P62502
IAFMSADWLIGKARS	LHFPL2	26	Q6ZUX7
TFTTVGDWLDAIKMG	EPHB3	926	P54753
AAMLIERSSDFGKTW	LAMB1	146	P07942
WRTKAGSVELLGAMA	GCN1	1511	Q92616
LLEMFSGELSWSADS	IRF5	426	Q13568
LFETFNWALSMGGKV	HUWE1	1166	Q7Z6Z7
SDTFAAGFMWLDKLG	HPSE	356	Q9Y251
GMKESEAAGLNSIFW	MFSD4B	261	Q5TF39
SGGMDAQLKIWSAED	PAAF1	151	Q9BRP4
ETSLSKELVASGMGW	ICAM3	66	P32942
KELVASGMGWAAFNL	ICAM3	71	P32942
WFKEETRLATGLDGM	OPCML	256	Q14982
MGNLSQLSSGEDKWL	NCOA4	546	Q13772
SGSDWVTIKFMKVDG	PREP	146	P48147
TRAGIEDSKKWGMLF	PCID2	156	Q5JVF3
AALSMGFSVKEDLSW	ATP6AP2	46	O75787
GVEAMSKSLAAEWGK	DECR1	216	Q16698
LAWELYLKMETSGES	TTC26	446	A0AVF1
LMSLFVLASKDGWVD	CACNA1G	1476	O43497
MEGAELAGKILSTWL	GPAT3	1	Q53EU6
KADIMFLVDSSWSIG	COL6A5	626	A8TX70
EASLWSSGFGMKLEA	GPAT2	21	Q6NUI2
SSDSGSGFWKALTFM	IFI6	31	P09912
DMEWKFGVTSGSSEL	COMMD7	136	Q86VX2
DLGKLLMQGSFSVWT	MCF2L	826	O15068
FSGKALDVWAMGVTL	CAMKK2	366	Q96RR4
MADRLLSFGSSWLEG	CUL9	1601	Q8IWT3
FLWDDSMALTTGGKD	EML2	626	O95834
PENFGSMLELSWKGT	FAH	356	P16930
PATGEWKDGLFSSIM	DNAH9	2196	Q9NYC9
DLLGSSSQLFWEPMK	GPX6	161	P59796
KWTSQDSLLGMEFSG	FASN	1591	P49327
LLSGSTSGWKDMFNV	DHRS11	106	Q6UWP2
AFGTRLLVSSDMKSW	SLC22A7	416	Q9Y694
SIKAIGWMSSHTDFG	SLC15A4	511	Q8N697
LDMFNWKKSSSGSLL	IFT140	181	Q96RY7
MFKDLGDLRESSLWT	KIF28P	946	B7ZC32
SLSFVMLTSKGWSLD	CYP8B1	146	Q9UNU6
DTDFGGNMKSVLTWK	OSGIN1	96	Q9UJX0
AKWKTSDGQMDGLTT	PELI1	171	Q96FA3
FMWAAGKGSDDVLRT	INVS	326	Q9Y283
TSAALTEDGRLFMWG	RPGR	151	Q92834
TAQREEWKMFIGGLS	HNRNPD	91	Q14103
ATATWLVKDSTGMLG	RUSF1	131	Q96GQ5
WKDTRTSGVVFTGLM	RTN2	351	O75298
MGKTFSQLGSWREDE	TMEM106A	1	Q96A25
VMTGKSGRNLSDFWE	HHLA1	191	C9JL84
MFVGGLSWDTSKKDL	HNRNPAB	71	Q99729
SGGESKSQFWRMVAL	QTRT1	231	Q9BXR0
EWLVGMLGAESTKLN	TOP2B	1056	Q02880
NLGAGMDTTFWRLKD	LCMT1	96	Q9UIC8
FRKMWALATGLGSEA	PLEKHG4	606	Q58EX7
LAAGDSKMAETSVGW	PIWIL2	126	Q8TC59
MWKVSALLFVLGSAS	PDPN	1	Q86YL7
YKWSILSSSGGEMLF	PKDREJ	491	Q9NTG1
LGVSGTMDLLDWSSL	PRODH	306	O43272
AFLAGMGWTSEKAEV	SLC9B2	371	Q86UD5
SWGARAGKSMSAEDL	SHROOM3	1211	Q8TF72
IALMDKEGLTALSWA	TANC2	1126	Q9HCD6
MFWLGGGREESISKL	SPATA16	291	Q9BXB7
DGKSAISLNDALMWA	WDR17	1291	Q8IZU2
TMFAEGVLLKKTFSW	SLC35D1	146	Q9NTN3
GKTSFESWIISQMAG	PRORP	136	O15091
LTSVMGKAAGEREFW	TCN2	381	P20062
SGGSWKLLTIDQDLM	APEH	406	P13798
LASAEGFLMTSEWAK	ADGRD2	701	Q7Z7M1
WLKESISDVGFGMLK	AGPS	626	O00116
DFMGWLGAIQKAAAS	ARAP1	941	Q96P48
KSSDTWFMLARIAGL	ATP1A4	421	Q13733
MWSLLTALSGKEADA	NCAPH	651	Q15003
MLEDTGFWLESKILS	NCAPG2	846	Q86XI2
WVKTDQALLMLFSDG	PLK3	566	Q9H4B4
EGASVSSAGLFMWKT	VWDE	1136	Q8N2E2
SSAGLFMWKTDLLTT	VWDE	1141	Q8N2E2
GWMIASGSQDKTVRF	WDR47	766	O94967
LEGLRLWKTAFSAMT	REV3L	1946	O60673
GKVNMSSEFLRFKWG	TAFAZZIN	151	Q16635
GIKVWDGLMEIDSFL	PLCXD2	136	Q0VAA5
VGSKDMSTWVFGAER	PWP2	161	Q15269
FWREIESIKDSSMGG	ARHGAP28	81	Q9P2N2
SDKVLMTFENLAAWG	WDFY4	2921	Q6ZS81
IAWAMASLADIKAGA	THUMPD2	286	Q9BTF0
TGWLEDFLMGMDSTL	RAET1G	191	Q6H3X3
LSTKWGETTFMAKLG	WAPL	31	Q7Z5K2
LLAISLAGMEWESKA	SLC12A3	271	P55017
FSRLWTDVMGILDGS	SASH1	41	O94885
SWMDGIASQIGAADK	SPTBN4	1956	Q9H254
MEDFWKFTEGSLLDG	PKD2	276	Q13563
GRSVASSKLWMLEFS	TEAD4	216	Q15561
ILEWAKELSLSGFSM	RWDD2B	206	P57060
ITGKAMLLEIFWSGS	SLF1	566	Q9BQI6
MLLEIFWSGSETSGL	SLF1	571	Q9BQI6
FLKSGSLDGAIWVMR	TOPAZ1	1421	Q8N9V7
LPATSWEDMKKGSFE	ZCCHC9	16	Q8N567
TEWGDSFGSMSVLIK	ZNF875	276	P10072
IAWKGDTLVLGDMDG	WDR11	716	Q9BZH6
GEGSLLFEAASMLLW	VRTN	81	Q9H8Y1
TNIGKFDMIWDRGAL	TPMT	141	P51580
GEVSKIVASMWDSLG	TOX4	251	O94842
LMKDSGGQTFSASWA	TTLL5	691	Q6EMB2
GWMFSKLDTSADLFL	SPOCK2	251	Q92563
LSTAMDKWGFGATLL	TYK2	791	P29597
VTLKDVGMDFTLGDW	ZNF473	6	Q8WTR7
LTFLGKDWGLEEMSE	KIAA0319	141	Q5VV43
SKWTKMFFGEGQASL	MYOM2	326	P54296