Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessentrainment of circadian clock by photoperiod

PPP1CA PPP1CB PPP1CC

4.64e-0525583GO:0043153
GeneOntologyBiologicalProcessphotoperiodism

PPP1CA PPP1CB PPP1CC

6.58e-0528583GO:0009648
GeneOntologyBiologicalProcessentrainment of circadian clock

PPP1CA PPP1CB PPP1CC

8.12e-0530583GO:0009649
GeneOntologyCellularComponentPTW/PP1 phosphatase complex

PPP1CA PPP1CB PPP1CC

7.04e-077583GO:0072357
GeneOntologyCellularComponentprotein phosphatase type 1 complex

PPP1CA PPP1CB PPP1CC

1.90e-0519583GO:0000164
GeneOntologyCellularComponentglycogen granule

PPP1CA PPP1CB

2.10e-048582GO:0042587
GeneOntologyCellularComponentprotein serine/threonine phosphatase complex

PPP1CA PPP1CB PPP1CC

4.80e-0455583GO:0008287
GeneOntologyCellularComponentphosphatase complex

PPP1CA PPP1CB PPP1CC

4.80e-0455583GO:1903293
DomainSTPPase_N

PPP1CA PPP1CB PPP1CC

2.99e-083593IPR031675
DomainSTPPase_N

PPP1CA PPP1CB PPP1CC

2.99e-083593PF16891
DomainSer/Thr-sp_prot-phosphatase

PPP1CA PPP1CB PPP1CC

8.37e-0613593IPR006186
DomainSER_THR_PHOSPHATASE

PPP1CA PPP1CB PPP1CC

8.37e-0613593PS00125
DomainPP2Ac

PPP1CA PPP1CB PPP1CC

8.37e-0613593SM00156
DomainTMEM183

TMEM183A TMEM183BP

9.81e-062592IPR026509
DomainCalcineurin-like_PHP_ApaH

PPP1CA PPP1CB PPP1CC

9.27e-0528593IPR004843
DomainMetallophos

PPP1CA PPP1CB PPP1CC

9.27e-0528593PF00149
DomainMetallo-depent_PP-like

PPP1CA PPP1CB PPP1CC

1.14e-0430593IPR029052
Domain-

PPP1CA PPP1CB PPP1CC

1.14e-04305933.60.21.10
DomainGasdermin

GSDMA GSDMC

1.46e-046592PF04598
DomainGasdermin

GSDMA GSDMC

2.71e-048592IPR007677
DomainCl-channel_core

CLCN3 CLCN5

3.48e-049592IPR014743
Domain-

CLCN3 CLCN5

3.48e-0495921.10.3080.10
DomainVoltage_CLC

CLCN3 CLCN5

3.48e-049592PF00654
DomainCl-channel_volt-gated

CLCN3 CLCN5

3.48e-049592IPR001807
DomainDynein_HC_stalk

DNHD1 DNAH8

8.71e-0414592IPR024743
DomainDynein_heavy_dom-2

DNHD1 DNAH8

8.71e-0414592IPR013602
DomainDHC_N2

DNHD1 DNAH8

8.71e-0414592PF08393
DomainMT

DNHD1 DNAH8

8.71e-0414592PF12777
DomainDHC_fam

DNHD1 DNAH8

1.00e-0315592IPR026983
DomainDynein_heavy_dom

DNHD1 DNAH8

1.00e-0315592IPR004273
DomainDynein_heavy

DNHD1 DNAH8

1.00e-0315592PF03028
DomainCBS

CLCN3 CLCN5

1.14e-0316592SM00116
DomainF-box_dom

FBXO8 TMEM183A TMEM183BP

1.72e-0375593IPR001810
DomainCBS_dom

CLCN3 CLCN5

1.80e-0320592IPR000644
DomainCBS

CLCN3 CLCN5

1.80e-0320592PF00571
DomainCBS

CLCN3 CLCN5

1.80e-0320592PS51371
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_MRAS_SHOC2_PP1_HOLOPHOSPHATASE

PPP1CA PPP1CB PPP1CC

1.57e-068443M47933
PathwayKEGG_MEDICUS_REFERENCE_CENPE_INTERACTION_WITH_NDC80_COMPLEX

PPP1CA PPP1CB PPP1CC

6.12e-0612443M47887
PathwayKEGG_MEDICUS_REFERENCE_DEPHOSPHORYLATION_OF_KINETOCHORE

PPP1CA PPP1CB PPP1CC

6.12e-0612443M47891
PathwayREACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_RSV_GENOME_REPLICATION_TRANSCRIPTION_AND_TRANSLATION

PPP1CA PPP1CB PPP1CC

1.54e-0516443M48235
PathwayREACTOME_TRIGLYCERIDE_CATABOLISM

PPP1CA PPP1CB PPP1CC

5.49e-0524443M10064
PathwayREACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING

PPP1CA PPP1CB PPP1CC

7.02e-0526443M628
PathwayREACTOME_TRIGLYCERIDE_METABOLISM

PPP1CA PPP1CB PPP1CC

2.22e-0438443M27856
PathwayREACTOME_SIGNALING_BY_MRAS_COMPLEX_MUTANTS

PPP1CB PPP1CC

2.63e-048442M38999
PathwayWP_COMMON_PATHWAYS_UNDERLYING_DRUG_ADDICTION

PPP1CA PPP1CB PPP1CC

2.78e-0441443M39655
PathwayWP_ENDOPLASMIC_RETICULUM_STRESS_RESPONSE_IN_CORONAVIRUS_INFECTION

PPP1CA PPP1CB PPP1CC

3.92e-0446443M39901
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

PPP1CA PPP1CB PPP1CC

4.18e-0447443M646
PathwayKEGG_REGULATION_OF_ACTIN_CYTOSKELETON

ITGA6 CHRM5 PPP1CA PPP1CB PPP1CC

5.05e-04213445M18306
PathwayWP_HIPPOMERLIN_SIGNALING_DYSREGULATION

ITGA6 PPP1CA PPP1CB PPP1CC

5.38e-04121444M39823
PathwayKEGG_LONG_TERM_POTENTIATION

PPP1CA PPP1CB PPP1CC

1.34e-0370443M3115
PathwayREACTOME_CIRCADIAN_CLOCK

PPP1CA PPP1CB PPP1CC

1.34e-0370443M938
Pubmed

Dissociation of SHP-1 from spinophilin during platelet activation exposes an inhibitory binding site for protein phosphatase-1 (PP1).

SGPL1 PPP1CA PPP1CB PPP1CC

1.20e-10660425785436
Pubmed

1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription.

PPP1CA PPP1CB PPP1CC

4.88e-09360325073485
Pubmed

Protein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clock.

PPP1CA PPP1CB PPP1CC

4.88e-09360321712997
Pubmed

Chromosomal localization of human, rat, and mouse protein phosphatase type 1 beta catalytic subunit genes (PPP1CB) by fluorescence in situ hybridization.

PPP1CA PPP1CB PPP1CC

4.88e-0936037857673
Pubmed

Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein.

PPP1CA PPP1CB PPP1CC

1.95e-08460316131488
Pubmed

Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1.

PPP1CA PPP1CB PPP1CC

1.95e-08460310194355
Pubmed

Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1.

PPP1CA PPP1CB PPP1CC

1.95e-08460322768081
Pubmed

Nuclear protein phosphatase-1 regulates HIV-1 transcription.

PPP1CA PPP1CB PPP1CC

1.95e-08460312788939
Pubmed

Protein phosphatase 1 inhibits p53 signaling by dephosphorylating and stabilizing Mdmx.

PPP1CA PPP1CB PPP1CC

1.95e-08460323277204
Pubmed

Binding of the concave surface of the Sds22 superhelix to the alpha 4/alpha 5/alpha 6-triangle of protein phosphatase-1.

PPP1CA PPP1CB PPP1CC

1.95e-08460312226088
Pubmed

N-CoR controls differentiation of neural stem cells into astrocytes.

PPP1CA PPP1CB PPP1CC

1.95e-08460312410313
Pubmed

Distinct roles for the α , β and γ1 isoforms of protein phosphatase 1 in the outside-in αIIbβ3 integrin signalling-dependent functions.

PPP1CA PPP1CB PPP1CC

4.87e-08560323197154
Pubmed

The heterotrimeric G protein Gβ1 interacts with the catalytic subunit of protein phosphatase 1 and modulates G protein-coupled receptor signaling in platelets.

PPP1CA PPP1CB PPP1CC

4.87e-08560328615442
Pubmed

Association of the type 1 protein phosphatase PP1 with the A-kinase anchoring protein AKAP220.

PPP1CA PPP1CB PPP1CC

4.87e-08560310209101
Pubmed

A PP1-PP2A phosphatase relay controls mitotic progression.

PPP1CA PPP1CB PPP1CC

4.87e-08560325487150
Pubmed

SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1.

PPP1CA PPP1CB PPP1CC

4.87e-08560320424263
Pubmed

The human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activity.

PPP1CA PPP1CB PPP1CC

4.87e-08560312016208
Pubmed

Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle.

PPP1CA PPP1CB PPP1CC

4.87e-08560311551964
Pubmed

The interaction of PP1 with BRCA1 and analysis of their expression in breast tumors.

PPP1CA PPP1CB PPP1CC

4.87e-08560317511879
Pubmed

SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1.

PPP1CA PPP1CB PPP1CC

9.73e-08660314640981
Pubmed

Inhibitory member of the apoptosis-stimulating proteins of the p53 family (iASPP) interacts with protein phosphatase 1 via a noncanonical binding motif.

PPP1CA PPP1CB PPP1CC

9.73e-08660321998301
Pubmed

Protein phosphatase 1 regulates the phosphorylation state of the polarity scaffold Par-3.

PPP1CA PPP1CB PPP1CC

9.73e-08660318641122
Pubmed

A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent inhibition of GSK-3beta.

PPP1CA PPP1CB PPP1CC

1.70e-07760312147701
Pubmed

Inhibitor-2 prevents protein phosphatase 1-induced cardiac hypertrophy and mortality.

PPP1CA PPP1CB PPP1CC

1.70e-07760318689497
Pubmed

SARP, a new alternatively spliced protein phosphatase 1 and DNA interacting protein.

PPP1CA PPP1CB PPP1CC

1.70e-07760317123353
Pubmed

The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1.

PPP1CA PPP1CB PPP1CC

2.72e-07860321930935
Pubmed

A protein phosphatase from human T cells augments tat transactivation of the human immunodeficiency virus type 1 long-terminal repeat.

PPP1CA PPP1CB PPP1CC

2.72e-07860312036313
Pubmed

Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation.

PPP1CA PPP1CB PPP1CC

2.72e-07860316262633
Pubmed

Consensus PP1 binding motifs regulate transcriptional corepression and alternative RNA splicing activities of the steroid receptor coregulators, p54nrb and PSF.

PPP1CA PPP1CB PPP1CC

4.07e-07960321566083
Pubmed

RRP1B targets PP1 to mammalian cell nucleoli and is associated with Pre-60S ribosomal subunits.

PPP1CA PPP1CB PPP1CC

4.07e-07960320926688
Pubmed

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts.

PPP1CA PPP1CB PPP1CC

1.06e-061260310830164
Pubmed

Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription.

PPP1CA PPP1CB PPP1CC

1.75e-061460316048649
Pubmed

NKG2D Engagement Alone Is Sufficient to Activate Cytokine-Induced Killer Cells While 2B4 Only Provides Limited Coactivation.

KLRK1 CD244

2.93e-06260234691037
Pubmed

The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases.

PPP1CB PPP1CC

2.93e-0626022544298
Pubmed

Origination and evolution of a human-specific transmembrane protein gene, c1orf37-dup.

TMEM183A TMEM183BP

2.93e-06260216644869
Pubmed

Protein phosphatase 1-dependent transcriptional programs for long-term memory and plasticity.

PPP1CB PPP1CC

2.93e-06260220592054
Pubmed

Chloride/proton antiporters ClC3 and ClC5 support bone formation in mice.

CLCN3 CLCN5

2.93e-06260238666049
Pubmed

PP-1α and PP-1γ display antagonism and differential roles in tumorigenicity of lung cancer cells.

PPP1CA PPP1CC

2.93e-06260223176181
Pubmed

Recruitment of activating NK-cell receptors 2B4 and NKG2D to membrane microdomains in mammalian cells is dependent on their transmembrane regions.

KLRK1 CD244

2.93e-06260225545687
Pubmed

Protein phosphatase 1 abrogates IRF7-mediated type I IFN response in antiviral immunity.

PPP1CA PPP1CB

2.93e-06260227469204
Pubmed

Spermiogenesis is impaired in mice bearing a targeted mutation in the protein phosphatase 1cgamma gene.

PPP1CA PPP1CC

2.93e-0626029882500
Pubmed

Regulation of HIV-1 transcription by protein phosphatase 1.

PPP1CA PPP1CB PPP1CC

3.26e-061760317266553
Pubmed

[Action of protein phosphatase-1 on Tat-dependent HIV-1 transcription and its related inhibitors].

PPP1CA PPP1CB PPP1CC

3.26e-061760321351466
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SLC12A6 GTF2IRD2B CLCN3 CLCN5 SETD5 POLQ CCDC191 DNAH8 SLC27A4 PPP1CA PPP1CB PPP1CC

5.45e-061442601235575683
Pubmed

New insights into the control of HIV-1 transcription: when Tat meets the 7SK snRNP and super elongation complex (SEC).

PPP1CA PPP1CB PPP1CC

8.43e-062360321360054
Pubmed

The PP1 binding code: a molecular-lego strategy that governs specificity.

PPP1CA PPP1CB

8.77e-06360222360570
Pubmed

Differential expression of natural killer cell activating receptors in blood versus bone marrow in patients with monoclonal gammopathy.

KLRK1 CD244

8.77e-06360223360454
Pubmed

Mutually exclusive binding of PP1 and RNA to AKAP149 affects the mitochondrial network.

PPP1CA PPP1CC

8.77e-06360219074462
Pubmed

PAI1: a novel PP1-interacting protein that mediates human plasma's anti-apoptotic effect in endothelial cells.

PPP1CA PPP1CB

8.77e-06360228296156
Pubmed

NK cell function triggered by multiple activating receptors is negatively regulated by glycogen synthase kinase-3β.

KLRK1 CD244

8.77e-06360226022178
Pubmed

NOM1 targets protein phosphatase I to the nucleolus.

PPP1CA PPP1CC

8.77e-06360217965019
Pubmed

The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation.

PPP1CA PPP1CC

8.77e-06360212138106
Pubmed

Stepwise phosphorylation of p65 promotes NF-κB activation and NK cell responses during target cell recognition.

KLRK1 CD244

8.77e-06360227221592
Pubmed

Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells.

PPP1CA PPP1CC

8.77e-06360211739654
Pubmed

NKG2D ligation relieves 2B4-mediated NK-cell self-tolerance in mice.

KLRK1 CD244

8.77e-06360224610736
Pubmed

Myr 8, a novel unconventional myosin expressed during brain development associates with the protein phosphatase catalytic subunits 1alpha and 1gamma1.

PPP1CA PPP1CC

8.77e-06360211588169
Pubmed

Characterization of protein phosphatases in mouse oocytes.

PPP1CA PPP1CC

8.77e-0636029882488
Pubmed

Support of bone mineral deposition by regulation of pH.

CLCN3 CLCN5

8.77e-06360230044661
Pubmed

XLP1 inhibitory effect by 2B4 does not affect DNAM-1 and NKG2D activating pathways in NK cells.

KLRK1 CD244

8.77e-06360224496997
Pubmed

Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation.

PPP1CA PPP1CB PPP1CC

9.63e-062460327754788
Pubmed

Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling.

PPP1CA PPP1CC

1.75e-05460223499489
Pubmed

PP1 and PP2A phosphatases--cooperating partners in modulating retinoblastoma protein activation.

PPP1CA PPP1CB

1.75e-05460222299668
Pubmed

TGF-β1 down-regulation of NKG2D/DAP10 and 2B4/SAP expression on human NK cells contributes to HBV persistence.

KLRK1 CD244

1.75e-05460222438812
Pubmed

Role of ClC-5 in renal endocytosis is unique among ClC exchangers and does not require PY-motif-dependent ubiquitylation.

CLCN3 CLCN5

1.75e-05460220351103
Pubmed

Fasting-induced protein phosphatase 1 regulatory subunit contributes to postprandial blood glucose homeostasis via regulation of hepatic glycogenesis.

PPP1CA PPP1CB

1.75e-05460221471512
Pubmed

NIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1.

PPP1CA PPP1CC

1.75e-05460210880350
Pubmed

Copy number variation influences gene expression and metabolic traits in mice.

KLRK1 CD244

1.75e-05460219648292
Pubmed

Identification of the spermatogenic zip protein Spz1 as a putative protein phosphatase-1 (PP1) regulatory protein that specifically binds the PP1cgamma2 splice variant in mouse testis.

PPP1CA PPP1CC

1.75e-05460215226296
Pubmed

Gasdermin D is the only Gasdermin that provides protection against acute Salmonella gut infection in mice.

GSDMA GSDMC

1.75e-05460237988464
Pubmed

Chloride and the endosomal-lysosomal pathway: emerging roles of CLC chloride transporters.

CLCN3 CLCN5

1.75e-05460217110406
Pubmed

Interaction of inhibitor-2 with the catalytic subunit of type 1 protein phosphatase. Identification of a sequence analogous to the consensus type 1 protein phosphatase-binding motif.

PPP1CA PPP1CC

1.75e-05460210807923
Pubmed

Cardiac-specific deletion of protein phosphatase 1β promotes increased myofilament protein phosphorylation and contractile alterations.

PPP1CB PPP1CC

1.75e-05460226334248
Pubmed

Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium.

GSDMA GSDMC

1.75e-05460219051310
Pubmed

Glucose-dependent regulation of AMP-activated protein kinase in MIN6 beta cells is not affected by the protein kinase A pathway.

PPP1CA PPP1CB

1.75e-05460223116618
Pubmed

Structural basis for protein phosphatase 1 regulation and specificity.

PPP1CA PPP1CB

1.75e-05460222284538
Pubmed

The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits.

PPP1CA PPP1CC

1.75e-05460212016225
Pubmed

Inhibitor-2 regulates protein phosphatase-1 complexed with NimA-related kinase to induce centrosome separation.

PPP1CA PPP1CC

1.75e-05460212221103
Pubmed

Phosphorylation of protein phosphatase 1 by cyclin-dependent protein kinase 5 during nerve growth factor-induced PC12 cell differentiation.

PPP1CA PPP1CC

1.75e-05460217202132
Pubmed

A vitamin D receptor-Ser/Thr phosphatase-p70 S6 kinase complex and modulation of its enzymatic activities by the ligand.

PPP1CA PPP1CC

1.75e-05460212036952
Pubmed

Synphilin-1A is a phosphoprotein phosphatase 1-interacting protein and affects PPP1 sorting to subcellular compartments.

PPP1CA PPP1CC

1.75e-05460224902662
Pubmed

Identification and characterization of a novel human PP1 phosphatase complex.

PPP1CA PPP1CB PPP1CC

2.12e-053160320516061
Pubmed

A quantitative telomeric chromatin isolation protocol identifies different telomeric states.

PPP1CA PPP1CB PPP1CC

2.81e-053460324270157
Pubmed

Members of a novel gene family, Gsdm, are expressed exclusively in the epithelium of the skin and gastrointestinal tract in a highly tissue-specific manner.

GSDMA GSDMC

2.92e-05560217350798
Pubmed

Dab2 stabilizes Axin and attenuates Wnt/beta-catenin signaling by preventing protein phosphatase 1 (PP1)-Axin interactions.

PPP1CA PPP1CC

2.92e-05560219581931
Pubmed

Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores.

PPP1CA PPP1CC

2.92e-05560222801782
Pubmed

A protein phosphatase-1gamma1 isoform selectivity determinant in dendritic spine-associated neurabin.

PPP1CB PPP1CC

2.92e-05560215016827
Pubmed

Human T-cell leukemia virus type 1 (HTLV-1) p12I down-modulates ICAM-1 and -2 and reduces adherence of natural killer cells, thereby protecting HTLV-1-infected primary CD4+ T cells from autologous natural killer cell-mediated cytotoxicity despite the reduction of major histocompatibility complex class I molecules on infected cells.

KLRK1 CD244

2.92e-05560217609265
Pubmed

Initiation factor 2B activity is regulated by protein phosphatase 1, which is activated by the mitogen-activated protein kinase-dependent pathway in insulin-like growth factor 1-stimulated neuronal cells.

PPP1CA PPP1CC

2.92e-05560212624094
Pubmed

HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint.

PPP1CB PPP1CC

2.92e-0556029009195
Pubmed

Novel Jbts17 mutant mouse model of Joubert syndrome with cilia transition zone defects and cerebellar and other ciliopathy related anomalies.

ISL1 CPLANE1

2.92e-05560225877302
Pubmed

An essential role for ClC-4 in transferrin receptor function revealed in studies of fibroblasts derived from Clcn4-null mice.

CLCN3 CLCN5

2.92e-05560219339555
Pubmed

The nuclear envelope protein, LAP1B, is a novel protein phosphatase 1 substrate.

PPP1CA PPP1CC

2.92e-05560224116158
Pubmed

ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2.

PPP1CA PPP1CB PPP1CC

3.94e-053860330629181
Pubmed

Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development.

NTNG2 SLC27A4

4.37e-05660212697906
Pubmed

Expression of CLCN voltage-gated chloride channel genes in human blood vessels.

CLCN3 CLCN5

4.37e-05660210198195
Pubmed

Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins.

PPP1CA PPP1CC

4.37e-05660223088536
Pubmed

Protein phosphatase-1 regulates Akt1 signal transduction pathway to control gene expression, cell survival and differentiation.

PPP1CA PPP1CB

4.37e-05660220186153
Pubmed

Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions.

PPP1CA PPP1CB PPP1CC

4.61e-054060323555304
Pubmed

Association of a protein phosphatase 1 activity with the human factor C1 (HCF) complex.

PPP1CA PPP1CC

6.11e-05760210637318
Pubmed

Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes.

PPP1CB PPP1CC

6.11e-05760217369396
InteractionPPP1R2C interactions

PPP1CA PPP1CB PPP1CC

9.51e-084593int:PPP1R2C
InteractionCSRNP2 interactions

PPP1CA PPP1CB PPP1CC

2.37e-075593int:CSRNP2
InteractionSFRP5 interactions

PPP1CA PPP1CB PPP1CC

4.74e-076593int:SFRP5
InteractionPPP1R2B interactions

PPP1CA PPP1CB PPP1CC

8.48e-0614593int:PPP1R2B
InteractionPPP1R3B interactions

PPP1CA PPP1CB PPP1CC

2.23e-0519593int:PPP1R3B
InteractionPLCL2 interactions

PPP1CA PPP1CB PPP1CC

2.23e-0519593int:PLCL2
InteractionCSRNP1 interactions

PPP1CA PPP1CB PPP1CC

3.05e-0521593int:CSRNP1
InteractionSFRP1 interactions

PPP1CA PPP1CB PPP1CC

5.24e-0525593int:SFRP1
InteractionUBXN2A interactions

PPP1CA PPP1CB PPP1CC

5.91e-0526593int:UBXN2A
InteractionPPP1R15B interactions

CHRM5 PPP1CA PPP1CB PPP1CC

9.77e-0582594int:PPP1R15B
InteractionPPP1R11 interactions

PPP1CA PPP1CB PPP1CC

1.01e-0431593int:PPP1R11
InteractionPPP1R3C interactions

PPP1CA PPP1CB PPP1CC

1.22e-0433593int:PPP1R3C
InteractionDELEC1 interactions

PPP1CA PPP1CB PPP1CC

1.34e-0434593int:DELEC1
InteractionSFRP2 interactions

PPP1CA PPP1CB PPP1CC

1.46e-0435593int:SFRP2
InteractionPHACTR3 interactions

PPP1CA PPP1CB PPP1CC

1.73e-0437593int:PHACTR3
InteractionRASSF9 interactions

PPP1CA PPP1CB PPP1CC

2.02e-0439593int:RASSF9
InteractionPPP1R15A interactions

PPP1CA PPP1CB PPP1CC

2.18e-0440593int:PPP1R15A
InteractionRASSF7 interactions

PPP1CA PPP1CB PPP1CC

2.52e-0442593int:RASSF7
InteractionLGALS9B interactions

SLC12A6 CLCN3 CLCN5

3.10e-0445593int:LGALS9B
InteractionUBXN2B interactions

PPP1CA PPP1CB PPP1CC

3.10e-0445593int:UBXN2B
InteractionC12orf57 interactions

ANKRD50 PPP1CA PPP1CC

3.10e-0445593int:C12orf57
InteractionRORC interactions

PPP1CA PPP1CB PPP1CC

3.10e-0445593int:RORC
InteractionADISSP interactions

PPP1CA PPP1CB PPP1CC

3.31e-0446593int:ADISSP
InteractionTPRN interactions

PPP1CA PPP1CB PPP1CC

3.99e-0449593int:TPRN
GeneFamilyProtein phosphatase catalytic subunits|EF-hand domain containing

PPP1CA PPP1CB PPP1CC

3.28e-0613423693
GeneFamilyChloride voltage-gated channels

CLCN3 CLCN5

2.34e-0410422302
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Lymphocytic-mature_NK_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 FRMD7 P2RY10 IL18R1

2.98e-06166605410843ad44f9b22d5476119ac0d7c9168e17ac4b
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-NK-NK-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CD244 RASA2 A4GALT SCUBE3 ITM2A

3.35e-06170605aaf29c2d4de172d366cbfc863bc741941667dde1
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KLRK1 CD244 P2RY10 IL18R1

4.04e-05142604c2a3cd9998fd9a8e6b2665347ca5c32511776488
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KLRK1 CD244 P2RY10 IL18R1

4.39e-0514560423a1ee986774725a9f5a9154fbbd023031fb0452
ToppCellControl-Lymphocytic_NKT-iNKT/MAIT-T-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KLRK1 CD244 IL18R1 SLC27A4

4.75e-05148604003e10bf477984248211b99d75daa8f7dcdb12c8
ToppCellLymphoid-Lymphoid-NK_cells|Lymphoid / shred on cell class and cell subclass (v4)

KLRK1 CD244 IL18R1 SEMA4C

4.75e-05148604d51a4b654a88d58dcdf29c2bc362c0cc1c40723a
ToppCell356C-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SLC15A2 SLC22A15 UGT2B4 CCDC191

5.14e-051516042dc132895609e4efe17954e31f53d9c1ccf256ef
ToppCellfacs-GAT-Fat-3m-Lymphocytic-NK_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 P2RY10 IL18R1

5.14e-051516043d07b79ecbcfad13116f0f2b039bd181a7ffe853
ToppCell356C-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SLC15A2 SLC22A15 UGT2B4 CCDC191

5.14e-0515160422afd8201eff8471da3456be065f2790de5e4bfe
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 FRMD7 IL18R1

5.41e-051536042a94092937267cd2282452dfde3d328d763d4294
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 FRMD7 IL18R1

5.41e-05153604ad33c81fe6ac10e7c263d42541aae0d796923bad
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOK6 GALNT17 P2RY10 ITM2A

5.69e-051556047aba8ef53c9170ad8ed955c904c8991097ab1e32
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 MKRN1 P2RY10

5.83e-051566045d97755db872d51522f6412a93704f3c79a084cd
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GALNT17 P2RY10 ITM2A SLC27A4

5.83e-05156604fbe23876f0899853cea3c5c4f3044a9cea064d5b
ToppCellAdult-Immune-mast_cell-D231|Adult / Lineage, Cell type, age group and donor

NTNG2 P2RY10 IL18R1 ITM2A

5.98e-051576044c63bb91f8708644e6ce2500072a4eeb8e1079dd
ToppCellCOVID-19_Severe-NK_CD56bright|World / disease group, cell group and cell class

KLRK1 TDRD15 RGN IL18R1

5.98e-051576049dcbabb377da7e93ec9f9abf09576a92877a7e02
ToppCellfacs-Spleen-nan-18m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 IL18R1 SEMA4C

5.98e-05157604a84377028c661f8f3ecae0f6082abdd859faf0c8
ToppCellCOVID-19_Severe-NK_CD56bright|COVID-19_Severe / disease group, cell group and cell class

KLRK1 RGN CD244 IL18R1

6.28e-051596049e2067f0d76769717f7048dab505fadd36bbb83e
ToppCell10x5'-Lung-Lymphocytic_NK-NK_CD56bright_CD16-|Lung / Manually curated celltypes from each tissue

KLRK1 GALNT17 RASA2 IL18R1

6.28e-05159604595643e9433265308e5aab7f906229025701cf6a
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 UTP6 CPLANE1 SEMA4C

6.43e-0516060455f599df6e3b7a5a505df4b094c834281311d94a
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 NTNG2 CD244 ITM2A

6.43e-05160604398f162e8a75c6cb5c3e4d1832e98d386e1f222b
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 UTP6 CPLANE1 SEMA4C

6.43e-05160604296e53e1e0786346d38db2d4188b9a1c0430627b
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-CD45____NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 NTNG2 CD244 ITM2A

6.43e-0516060412aaab0291035f578e2433efd169ae72f393a5a5
ToppCellControl-Mast_cells-Transitioning_MDM|Control / group, cell type (main and fine annotations)

NTNG2 IL18R1 SEMA4C ZNF445

6.59e-051616045807ee48f871a3eb24ebf78fd107cf5f2a4ec846
ToppCelldroplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLRK1 CD244 P2RY10 IL18R1

6.59e-05161604cd4a736d0cec31477c6e8d3b07a04ede1559854b
ToppCelldroplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLRK1 CD244 P2RY10 IL18R1

6.59e-0516160428930ba576625b98cc15993d1499e9dc5edbb5a9
ToppCelldroplet-Heart-nan-24m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 MKRN1 P2RY10

6.59e-051616047e60001637ef0f6fc67ef8a36ab80ebb25b0b0ab
ToppCelldroplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLRK1 CD244 P2RY10 IL18R1

6.75e-05162604ccba6d8d644fe56060ad388ec3a062b7e3b9f086
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 P2RY10 IL18R1

6.91e-05163604a0315855c354e830e109d41bd6e3396488aa8de9
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 IL18R1 ITM2A

7.08e-051646049fed5df40f50bde35db8bf89c291cbdc0e104112
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 IL18R1 ITM2A

7.08e-05164604e712d6b89461f741dbd773ba9a27ecaddf97cbaa
ToppCelldroplet-Liver-nan-3m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 CCDC191 DNAH8

7.08e-05164604950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 P2RY10 IL18R1

7.08e-05164604a59078c8f88e416e940c9b15151ce7de1bbe987e
ToppCelldroplet-Liver-nan-3m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 CCDC191 DNAH8

7.08e-05164604c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 P2RY10 IL18R1

7.08e-05164604e9e5a1462d8ed60b2e5bf603c8c47eb85bce83d5
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KLRK1 CD244 POLQ IL18R1

7.08e-05164604ae09e5aabd1347b865474255e7411c04f63efb3b
ToppCelldroplet-Liver-nan-3m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 CCDC191 DNAH8

7.08e-05164604bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCellfacs-Marrow-KLS-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOK6 CLCN3 MKRN1 PPP1CB

7.25e-051656044f95c2fe5ab4416c736fe0d1936695a2b26777eb
ToppCellfacs-Marrow-KLS-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOK6 CLCN3 MKRN1 PPP1CB

7.25e-051656043e913b49a868fdd5589200ae3e9be77c0938ba14
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 IL18R1 ITM2A

7.25e-051656048741df8066a44c841752a99ad306d26ea68f5344
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 CD244 P2RY10 IL18R1

7.42e-051666040b7503e27e26dcbf7f1b893c32ce0b21ce58bd4a
ToppCelldroplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLRK1 CD244 P2RY10 IL18R1

7.59e-05167604895844a45721988788d01120eb880603ba3ca139
ToppCelldroplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLRK1 CD244 P2RY10 IL18R1

7.59e-05167604cde82e3dacf347226a78873b166608b7851b34d4
ToppCelldroplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLRK1 CD244 P2RY10 IL18R1

7.59e-051676046f54a699d9266c5f09ed890a11b403a6c8476fc1
ToppCellfacs-Heart-LA-24m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 DOK6 P2RY10 IL18R1

7.59e-05167604ed75e9715c795e1cc8e58c8a90ed392569404147
ToppCellfacs-Heart-LA-24m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 DOK6 P2RY10 IL18R1

7.59e-05167604f34b34f531b9ed548ed5701305898092c41b9a9b
ToppCellImmune_cells-NK_cells|Immune_cells / Lineage and Cell class

KLRK1 CD244 IL18R1 ITM2A

7.77e-05168604125d70c37eb49eb4d1f503bb8d536b225254c7cb
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNHD1 NTNG2 POLQ TMEM100

7.95e-051696048a6d05b5d60b2b2e43a8ff7521feb79cd6dbd940
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

SLC12A6 SLC15A2 ITGA6 ANKRD50

8.32e-05171604adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND01-03-samps / Age Group, Lineage, Cell class and subclass

NTNG2 ITGA6 ANKRD50 TMEM100

8.90e-05174604b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCN5 SORCS2 TMEM100 DNAH8

9.30e-051766047292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCN5 SORCS2 TMEM100 DNAH8

9.30e-0517660488ca2f83d8301633232735f39b0683efe49d0b86
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-NK-NK-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RASA2 A4GALT SLC22A15 ZNF445

1.04e-04181604a7f0a83e4f48eca8e753bda13c744cf41359fcc0
ToppCellfacs-Trachea-nan-24m-Lymphocytic|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 P2RY10 IL18R1 PPP1CC

1.08e-04183604568c7e3bde7c6ad2c28ec02c2b073f482c337698
ToppCellfacs-Trachea-nan-24m-Lymphocytic-T_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 P2RY10 IL18R1 PPP1CC

1.08e-041836042b3ecfc51cdc5333345692747f4fed4c746a769d
ToppCellfacs-Trachea-nan-24m-Lymphocytic-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 P2RY10 IL18R1 PPP1CC

1.08e-0418360479d7aac3b2483ca32430af5ac9f0e578ae064894
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GALNT17 A4GALT SORCS2 TMEM100

1.13e-041856047dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCellfacs-Trachea-24m-Hematologic-lymphocytic-T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLRK1 P2RY10 IL18R1 PPP1CC

1.17e-04187604e4a219483118288d414d9017b81927255a5ab8bb
ToppCellfacs-Trachea-24m-Hematologic-lymphocytic-T_cell-T_cell_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLRK1 P2RY10 IL18R1 PPP1CC

1.17e-0418760481286565fcd51252c444e490b5f6d401c83b4666
ToppCellremission-B_memory|World / disease stage, cell group and cell class

SLC15A2 P2RY10 CCDC191 DNAH8

1.25e-04190604c3f55f752e47b5a71e111367cdbed4a39ab5cb21
ToppCellfacs-Trachea-24m-Hematologic-lymphocytic|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLRK1 P2RY10 IL18R1 PPP1CC

1.25e-0419060410f7d33fd1ff096f8fe5b7b11a58819d6cc14fbc
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Hematologic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCN5 MKRN1 PPP1CB

1.26e-04726035e5eb8c7014396767f3dc7d99cb552edd273bfbd
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Hematologic-erythroblast|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCN5 MKRN1 PPP1CB

1.26e-047260378e158835ec2a37faadf5acdbb62f266cc184e44
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Hematologic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCN5 MKRN1 PPP1CB

1.26e-0472603c4bf1d59845fa54aeb2c8ebeda17bba6641cfb3d
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-erythrocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 NTNG2 MKRN1

1.37e-04746036f222ebf7cb106bbb2ae3fb3cda660dfec3ea5d0
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P2RY10 IL18R1 DNAH8 ITM2A

1.41e-041966049a28571e01d020e2ebe77690619182f4e4ffe696
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

P2RY10 ITGA6 ITM2A PPP1CB

1.44e-04197604479841809554a9d0b1e4f23da6e657392b0f4971
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KLRK1 DOK6 SCUBE3 SEMA4C

1.44e-04197604e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IQCH RGS22 CPLANE1 CCDC191

1.44e-0419760474a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA6 IL18R1 TMEM100 ITM2A

1.46e-041986042400f8b8c51739ea2ae2b9f24f44eaeefa2bb6fc
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA6 IL18R1 TMEM100 ITM2A

1.46e-0419860440c2171e79f578c9116d872c189f953dc61d052d
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Capillary|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ITGA6 IL18R1 TMEM100 ITM2A

1.49e-041996043fea92affacd4c1f588fa81807df35d6c69b7241
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Capillary-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ITGA6 IL18R1 TMEM100 ITM2A

1.49e-04199604993999adf346b4fd557989bc53c17eb0ccb996c9
ToppCelldistal-1-Endothelial-Capillary|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ITGA6 IL18R1 TMEM100 ITM2A

1.49e-041996044b22769882fdd83f9cdca59e4d39ef441e62856b
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A4GALT ITGA6 IL18R1 TMEM100

1.49e-04199604e2d5c5cab102e67b0131b02392d81adaedc15965
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA6 IL18R1 TMEM100 ITM2A

1.49e-041996046cfe5a3d0ad530411ebc11decb4ab4c529e018d5
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Capillary|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

ITGA6 IL18R1 TMEM100 ITM2A

1.49e-0419960489f4db619fbed90f7fdf6ece7a671e514b5c6d76
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA6 IL18R1 TMEM100 ITM2A

1.52e-04200604ec9a18576a3d08ddfceb70d114c4ab861fbb0d08
ToppCellParenchyma_COVID-19-Endothelial-TX-Capillary|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ITGA6 IL18R1 TMEM100 ITM2A

1.52e-042006046c0498a5868891e8e22c03469d00669b20249b1a
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Neuronal-Intermediate|GW08 / Sample Type, Dataset, Time_group, and Cell type.

RGN IQCH SLC15A2 ITM2A

1.52e-04200604401d50fa394fa863fa7836344110ae5c7af3250a
ToppCellmedial-Endothelial-Capillary|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ITGA6 IL18R1 TMEM100 ITM2A

1.52e-04200604fd4dcdc67db2a5dbdd54bd2ae975c66df904d4d8
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA6 IL18R1 TMEM100 ITM2A

1.52e-0420060424e43d3d16d07571f77e0cd5b2e4758c6ff802cb
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Capillary-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ITGA6 IL18R1 TMEM100 ITM2A

1.52e-042006047020045b933cb104fb99b79524cb0d4734b8636d
ToppCelldistal-2-Endothelial-Capillary|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ITGA6 IL18R1 TMEM100 ITM2A

1.52e-042006048daf09d63c2fda6da6e5b66f96e7449ee8b17029
ToppCellmedial-2-Endothelial-Capillary|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ITGA6 IL18R1 TMEM100 ITM2A

1.52e-04200604e4f390dfd4dd25600f0f7a17c5523283a5966e92
ToppCellmedial-Endothelial-Capillary-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ITGA6 IL18R1 TMEM100 ITM2A

1.52e-042006044291b5453e98e20ec8150a96ccc865a5964bc645
ToppCellControl_saline-Endothelial-Endothelial|Control_saline / Treatment groups by lineage, cell group, cell type

A4GALT ITGA6 TMEM100 ITM2A

1.52e-04200604e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCellcellseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ITGA6 IL18R1 TMEM100 ITM2A

1.52e-0420060413f6ac0dfc9206dd2e6cbd84357a5883952ee5c7
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Capillary|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ITGA6 IL18R1 TMEM100 ITM2A

1.52e-04200604e9913511a129bb3cee85e7ebf565b951dab91542
ToppCellControl_saline-Endothelial|Control_saline / Treatment groups by lineage, cell group, cell type

A4GALT ITGA6 TMEM100 ITM2A

1.52e-042006043372c488a39fe812fa94e4f0564594186fea3db5
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKRN1 POLQ PPP1CB

1.99e-04846036c8018d65df335c81fe4099a34e0053c8dbcf88d
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-red_blood_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 NTNG2 MKRN1

2.13e-04866034d20625cb666cd09509e07e8db527b94b379509a
ToppCelldroplet-Spleen-nan-21m-Hematologic-erythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKRN1 PPP1CB SEMA4C

2.36e-0489603e7d9498a1a3aa974fdd68b394c3eaff8e35c9727
ComputationalNeighborhood of PTPRB

NTNG2 CLCN3 SGPL1 P2RY10 ISL1 RREB1

8.87e-05254326MORF_PTPRB
ComputationalNeighborhood of FSHR

NTNG2 CLCN3 SGPL1 P2RY10 ISL1 RREB1

1.49e-04279326MORF_FSHR
ComputationalNeighborhood of KDR

NTNG2 SGPL1 P2RY10 RREB1

1.63e-0494324MORF_KDR
ComputationalNeighborhood of CAMK4

NTNG2 CLCN3 SGPL1 P2RY10 ISL1 RREB1

1.84e-04290326MORF_CAMK4
ComputationalNeighborhood of ERCC4

NTNG2 CLCN3 SGPL1 P2RY10 ISL1 RREB1

3.18e-04321326MORF_ERCC4
ComputationalNeighborhood of IFNA1

NTNG2 CLCN3 P2RY10 ISL1 RREB1

3.18e-04205325MORF_IFNA1
ComputationalNeighborhood of CASP10

NTNG2 SGPL1 P2RY10 RREB1

3.79e-04117324MORF_CASP10
ComputationalNeighborhood of TTN

NTNG2 CLCN3 RREB1

4.27e-0450323MORF_TTN
ComputationalNeighborhood of CD8A

NTNG2 SGPL1 P2RY10 RREB1

5.02e-04126324MORF_CD8A
ComputationalNeighborhood of IL16

NTNG2 CLCN3 SGPL1 P2RY10 RREB1

6.42e-04239325MORF_IL16
ComputationalNeighborhood of RAD51L3

NTNG2 CLCN3 SGPL1 P2RY10 ISL1 RREB1

8.57e-04387326MORF_RAD51L3
ComputationalNeighborhood of MAGEA8

NTNG2 CLCN3 P2RY10 ISL1 RREB1

9.40e-04260325MORF_MAGEA8
ComputationalNeighborhood of PDCD1

NTNG2 SGPL1 RREB1

1.29e-0373323MORF_PDCD1
ComputationalNeighborhood of MAGEA9

NTNG2 CLCN3 SGPL1 P2RY10 ISL1 RREB1

1.36e-03423326MORF_MAGEA9
ComputationalNeighborhood of TNFRSF6

NTNG2 SGPL1 P2RY10 RREB1

1.44e-03167324MORF_TNFRSF6
ComputationalNeighborhood of PPP2R5B

NTNG2 SGPL1 P2RY10 RREB1

1.64e-03173324MORF_PPP2R5B
ComputationalNeighborhood of DMPK

NTNG2 CLCN3 P2RY10 RREB1

1.71e-03175324MORF_DMPK
ComputationalNeighborhood of MLLT10

NTNG2 CLCN3 SGPL1 P2RY10 RREB1

1.83e-03302325MORF_MLLT10
ComputationalNeighborhood of PRKCA

NTNG2 CLCN3 P2RY10 RREB1

1.93e-03181324MORF_PRKCA
ComputationalNeighborhood of CTSB

NTNG2 CLCN3 P2RY10 RREB1

2.18e-03187324MORF_CTSB
ComputationalNeighborhood of BNIP1

NTNG2 SGPL1 P2RY10 RREB1

2.31e-03190324MORF_BNIP1
ComputationalNeighborhood of SUPT3H

NTNG2 CLCN3 P2RY10 ISL1 RREB1

2.62e-03328325MORF_SUPT3H
ComputationalNeighborhood of ATF2

NTNG2 CLCN3 P2RY10 ISL1 RREB1

2.69e-03330325MORF_ATF2
DiseaseDent disease (implicated_via_orthology)

CLCN3 CLCN5

1.06e-053562DOID:0050699 (implicated_via_orthology)
Diseaseosteopetrosis (implicated_via_orthology)

CLCN3 CLCN5

7.38e-057562DOID:13533 (implicated_via_orthology)
Diseasecancer (implicated_via_orthology)

PHC3 ITGA6 PPP1CA PPP1CB PPP1CC

1.56e-04268565DOID:162 (implicated_via_orthology)
DiseaseCharcot-Marie-Tooth disease (is_implicated_in)

SLC12A6 MFN2

2.31e-0412562DOID:10595 (is_implicated_in)
DiseaseNoonan-Like Syndrome With Loose Anagen Hair

RASA2 PPP1CB

5.93e-0419562C3501846
DiseaseCostello syndrome (disorder)

RASA2 PPP1CB

5.93e-0419562C0587248
DiseaseNoonan syndrome-like disorder with loose anagen hair

RASA2 PPP1CB

5.93e-0419562C1843181
DiseaseCardio-facio-cutaneous syndrome

RASA2 PPP1CB

5.93e-0419562C1275081
DiseaseLEOPARD Syndrome

RASA2 PPP1CB

7.98e-0422562C0175704
DiseaseCharcot-Marie-Tooth disease (implicated_via_orthology)

SGPL1 MFN2

9.51e-0424562DOID:10595 (implicated_via_orthology)
DiseaseNoonan Syndrome

RASA2 PPP1CB

9.51e-0424562C0028326
Diseasemelanoma

KLRK1 IQCH RASA2 SLC15A2

1.27e-03248564C0025202
Diseaseasthma, seasonal allergic rhinitis

GSDMA IL18R1

1.69e-0332562EFO_0003956, MONDO_0004979
Diseasefatty liver disease (biomarker_via_orthology)

MFN2 SLC27A4

1.80e-0333562DOID:9452 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
ICIFWKRQREKNKAS

BTNL10

271

A8MVZ5
LAVFFLWCQQKKRAR

C1orf167

626

Q5SNV9
RVFKKWCSIRSLAES

A4GALT

256

Q9NPC4
ICAFLLRKKRFGQWT

AFAP1

156

Q8N556
FCLVLRKRKSTLFWG

GSDMA

36

Q96QA5
FVILRKKKDSRSSFW

GSDMC

36

Q9BYG8
WLCQRLFVRKQFAKV

ANKRD50

336

Q9ULJ7
YCLLRKSFTCWKKNV

DNHD1

366

Q96M86
IGKKNFKKRWFCLTS

RASA2

621

Q15283
IQATWKCYKARKFFL

IQCH

376

Q86VS3
KWKLNVIRRNKHSCF

IL18R1

106

Q13478
WPRFIRHKCKQRFTK

MAK16

101

Q9BXY0
NTFNWAKIRKLSFKR

FRMD7

221

Q6ZUT3
IKKFQFIKSLRCFWK

OR51G1

306

Q8NGK1
KKSDFSTRWQKQRCP

KLRK1

26

P26718
KRLLNCFARVWFSEK

DNAH8

4126

Q96JB1
AKFIFCTRTLNWKKL

FBXO8

171

Q9NRD0
LVFILWKCGFFKRSR

ITGA6

1071

P23229
CSKKFALSRWNRKPD

PHC3

816

Q8NDX5
TWTTKAKERAFKRQF

MFN2

651

O95140
KRRYNIKLWKTFTDC

PPP1CA

141

P62136
RRFNIKLWKTFTDCF

PPP1CB

141

P62140
FWTPKSIKTRRCIFK

CPLANE1

1706

Q9H799
LGIFRRCWLVFKKAS

DOK6

21

Q6PKX4
LFQTFIKEWRCKKRF

POLQ

1836

O75417
KFCVHFLQKKIFRAW

CCDC191

831

Q8NCU4
FIRTNIAWCRKRKTT

CLCN5

406

P51795
CDKVKSSLYKRWNFI

GALNT17

541

Q6IS24
FNKRAIDKCWKIRHF

ITM2A

236

O43736
ANCVRWRKKFSFMCK

FAM102B

51

Q5T8I3
FLRVEKSLKKFCINW

GTF2IRD2B

596

Q6EKJ0
KSLKKFCINWSRLVS

GTF2IRD2B

601

Q6EKJ0
KWFGRKRTLSAFLCL

SLC22A15

361

Q8IZD6
KQHKVWRKCSIRIFT

SLC12A6

931

Q9UHW9
AFTARSRKLWINFKT

SCUBE3

886

Q8IX30
FKCIWFAISNRFKNR

SLC15A2

256

Q16348
ACFCVWRRKRKEKQS

CD244

246

Q9BZW8
LWVLCRFISKKNKAI

P2RY10

56

O00398
LKCIRKWRSAKQFES

MKRN1

311

Q9UHC7
CGKCKKNFRTRSWRA

NTNG2

316

Q96CW9
FCKKWATKTRLSKVF

UTP6

116

Q9NYH9
LCTFSRAKKIIIFVW

TRHR

136

P34981
PVSCKLFSWTRKAFR

TDRD15

871

B5MCY1
KWISSSCKIIAFRKA

RGS22

1011

Q8NE09
TLKNSKCLLFWCRKI

TMEM183BP

231

Q1AE95
QQRSFRKRKSTSWCI

SORCS2

671

Q96PQ0
TFSSCKKRWIKQALE

SETD5

776

Q9C0A6
AKKVCRWDSFTKQVQ

RGN

36

Q15493
RVWFQNKRCKDKKRS

ISL1

226

P61371
LQRKWTTFLKARLAC

SEMA4C

271

Q9C0C4
FQPESLWSRFKKKCF

SGPL1

61

O95470
TFRKTFKMLLLCRWK

CHRM5

501

P08912
NIAWCRRRKSTKFGK

CLCN3

411

P51790
FRFCVKAKRKTNLTW

TAS2R7

156

Q9NYW3
TLKNSKCLLFWCRKI

TMEM183A

231

Q8IXX5
KKVCSVCNKRFWSLQ

RREB1

1511

Q92766
RKKFSASRFWDDCIK

SLC27A4

311

Q6P1M0
FIITKCLFCVWKFVR

UGT2B4

506

P06133
KRRYNIKLWKTFTDC

PPP1CC

141

P36873
ASSALCWKVRQRSKK

TMEM100

101

Q9NV29
VLNKIREFKTCFFSW

XNDC1N

171

Q6ZNB5
KAFKCRVCGKAFRWS

ZNF445

511

P59923
KCTKCRKTFRWRSNF

ZNF445

626

P59923
KSFTWKSRLRIHQKC

ZNF484

531

Q5JVG2