Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionantigen binding

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-5 IGKV1D-39 IGKV1D-33 IGKV1D-12 IGKV3-20

1.85e-051901198GO:0003823
GeneOntologyMolecularFunctioncalmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity

PDE1A PDE1B

1.05e-0431192GO:0048101
GeneOntologyMolecularFunctioncalmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity

PDE1A PDE1B

1.05e-0431192GO:0004117
GeneOntologyBiologicalProcessimmunoglobulin production

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-13 IGKV1D-12 IGKV3-20

1.89e-1224112716GO:0002377
GeneOntologyBiologicalProcessproduction of molecular mediator of immune response

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 MALT1 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-13 IGKV1D-12 IGKV3-20

4.72e-1040312717GO:0002440
GeneOntologyBiologicalProcessadaptive immune response

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 MALT1 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-13 IGKV1D-12 IGKV3-20 NCKAP1L

3.84e-0683812718GO:0002250
GeneOntologyCellularComponentimmunoglobulin complex

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-13 IGKV1D-12 IGKV3-20

4.03e-1516612616GO:0019814
GeneOntologyCellularComponentIgM immunoglobulin complex, circulating

IGKV3D-20 IGKV3D-11 IGKV3-20

1.17e-0581263GO:0071754
GeneOntologyCellularComponentpentameric IgM immunoglobulin complex

IGKV3D-20 IGKV3D-11 IGKV3-20

1.17e-0581263GO:0071756
GeneOntologyCellularComponentmonomeric IgA immunoglobulin complex

IGKV3D-20 IGKV3D-11 IGKV3-20

1.75e-0591263GO:0071748
GeneOntologyCellularComponentpolymeric IgA immunoglobulin complex

IGKV3D-20 IGKV3D-11 IGKV3-20

2.49e-05101263GO:0071749
GeneOntologyCellularComponentIgA immunoglobulin complex, circulating

IGKV3D-20 IGKV3D-11 IGKV3-20

2.49e-05101263GO:0071746
GeneOntologyCellularComponentsecretory IgA immunoglobulin complex

IGKV3D-20 IGKV3D-11 IGKV3-20

2.49e-05101263GO:0071751
GeneOntologyCellularComponentIgA immunoglobulin complex

IGKV3D-20 IGKV3D-11 IGKV3-20

9.23e-05151263GO:0071745
GeneOntologyCellularComponentIgM immunoglobulin complex

IGKV3D-20 IGKV3D-11 IGKV3-20

9.23e-05151263GO:0071753
GeneOntologyCellularComponentimmunoglobulin complex, circulating

IGKV3D-20 IGKV3D-11 IGKV3-20

1.37e-04171263GO:0042571
GeneOntologyCellularComponentphotoreceptor connecting cilium

PCDHB13 PCDHB8 KIAA1549 IFT52

1.99e-04481264GO:0032391
GeneOntologyCellularComponentblood microparticle

IGKV1-39 IGKV1-17 IGKV1-5 IGKV1D-33 IGKV1D-12 IGKV3-20

2.41e-041441266GO:0072562
GeneOntologyCellularComponentdynein complex

TPR DNAH1 DYNC1H1 DYNC1LI2

3.15e-04541264GO:0030286
GeneOntologyCellularComponentcytoplasmic dynein complex

TPR DYNC1H1 DYNC1LI2

3.95e-04241263GO:0005868
GeneOntologyCellularComponentcilium

PDE1A ABCC4 FBXL13 SPEF2 PCDHB13 PCDHB8 ARFGEF2 KIAA1549 CDH23 DNAH1 IFT52 VCAN KCNJ10 TEKT4

1.04e-0389812614GO:0005929
GeneOntologyCellularComponentnon-motile cilium

PCDHB13 PCDHB8 KIAA1549 CDH23 IFT52 VCAN

1.22e-031961266GO:0097730
GeneOntologyCellularComponentciliary transition zone

PCDHB13 PCDHB8 KIAA1549 IFT52

1.46e-03811264GO:0035869
GeneOntologyCellularComponentphotoreceptor cell cilium

PCDHB13 PCDHB8 KIAA1549 IFT52 VCAN

1.55e-031391265GO:0097733
GeneOntologyCellularComponent9+0 non-motile cilium

PCDHB13 PCDHB8 KIAA1549 IFT52 VCAN

2.36e-031531265GO:0097731
Domain-

COL6A3 SEC24A MATN3 COL6A5 ITIH3

7.54e-057411053.40.50.410
DomainPDEase_N

PDE1A PDE1B

1.03e-0431102IPR013706
DomainPDEase_I_N

PDE1A PDE1B

1.03e-0431102PF08499
DomainDCB_dom

ARFGEF2 ARFGEF1

2.05e-0441102IPR032629
DomainSec7_C

ARFGEF2 ARFGEF1

2.05e-0441102IPR015403
DomainDUF1981

ARFGEF2 ARFGEF1

2.05e-0441102PF09324
DomainSec7_N

ARFGEF2 ARFGEF1

2.05e-0441102IPR032691
DomainSec7_N

ARFGEF2 ARFGEF1

2.05e-0441102PF12783
DomainDCB

ARFGEF2 ARFGEF1

2.05e-0441102PF16213
DomainVWF_A

COL6A3 SEC24A MATN3 COL6A5 ITIH3

2.98e-04991105IPR002035
DomainVWA

COL6A3 MATN3 COL6A5 ITIH3

3.30e-04561104PF00092
DomainCadherin_CS

DCHS2 DSG2 PCDHB13 PCDHB8 CDH23

4.65e-041091105IPR020894
DomainRNase_PH_C

EXOSC8 PNPT1

5.08e-0461102PF03725
Domain-

EXOSC8 PNPT1

5.08e-04611023.30.230.70
DomainPNPase/RNase_PH_dom

EXOSC8 PNPT1

5.08e-0461102IPR027408
DomainCADHERIN_1

DCHS2 DSG2 PCDHB13 PCDHB8 CDH23

5.48e-041131105PS00232
DomainCadherin

DCHS2 DSG2 PCDHB13 PCDHB8 CDH23

5.48e-041131105PF00028
DomainCADHERIN_2

DCHS2 DSG2 PCDHB13 PCDHB8 CDH23

5.70e-041141105PS50268
Domain-

DCHS2 DSG2 PCDHB13 PCDHB8 CDH23

5.70e-0411411052.60.40.60
DomainCA

DCHS2 DSG2 PCDHB13 PCDHB8 CDH23

5.94e-041151105SM00112
DomainCadherin-like

DCHS2 DSG2 PCDHB13 PCDHB8 CDH23

6.17e-041161105IPR015919
DomainCadherin

DCHS2 DSG2 PCDHB13 PCDHB8 CDH23

6.67e-041181105IPR002126
DomainExoRNase_PH_dom2

EXOSC8 PNPT1

7.08e-0471102IPR015847
DomainRNase_PH

EXOSC8 PNPT1

7.08e-0471102PF01138
DomainHATC_C_dom

ZNF862 SPEF2

9.40e-0481102IPR008906
DomainDimer_Tnp_hAT

ZNF862 SPEF2

9.40e-0481102PF05699
DomainRibosomal_S5_D2-typ_fold

EXOSC8 EFTUD2 PNPT1

1.04e-03341103IPR020568
DomainVWFA

COL6A3 MATN3 COL6A5 ITIH3

1.40e-03821104PS50234
DomainExoRNase_PH_dom1

EXOSC8 PNPT1

1.50e-03101102IPR001247
DomainVWA

COL6A3 MATN3 COL6A5 ITIH3

1.53e-03841104SM00327
DomainEGF_3

MATN3 CUBN LRP1B CNTNAP5 VCAN OTOG

2.69e-032351106PS50026
DomainDynein_heavy_chain_D4_dom

DNAH1 DYNC1H1

2.99e-03141102IPR024317
DomainDynein_HC_stalk

DNAH1 DYNC1H1

2.99e-03141102IPR024743
DomainDynein_heavy_dom-2

DNAH1 DYNC1H1

2.99e-03141102IPR013602
DomainDHC_N2

DNAH1 DYNC1H1

2.99e-03141102PF08393
DomainATPase_dyneun-rel_AAA

DNAH1 DYNC1H1

2.99e-03141102IPR011704
DomainMT

DNAH1 DYNC1H1

2.99e-03141102PF12777
DomainAAA_8

DNAH1 DYNC1H1

2.99e-03141102PF12780
DomainAAA_5

DNAH1 DYNC1H1

2.99e-03141102PF07728
DomainDHC_fam

DNAH1 DYNC1H1

3.43e-03151102IPR026983
DomainDynein_heavy

DNAH1 DYNC1H1

3.43e-03151102PF03028
Domain-

ARFGEF2 ARFGEF1

3.43e-031511021.10.1000.11
DomainDynein_heavy_dom

DNAH1 DYNC1H1

3.43e-03151102IPR004273
DomainSec7

ARFGEF2 ARFGEF1

3.43e-03151102PF01369
DomainSec7_alpha_orthog

ARFGEF2 ARFGEF1

3.43e-03151102IPR023394
DomainEGF-like_dom

MATN3 CUBN LRP1B CNTNAP5 VCAN OTOG

3.57e-032491106IPR000742
DomainQuinoprotein_ADH-like_supfam

EML6 AASDH PWP2

3.76e-03531103IPR011047
DomainSEC7

ARFGEF2 ARFGEF1

3.91e-03161102PS50190
DomainSec7

ARFGEF2 ARFGEF1

3.91e-03161102SM00222
DomainSec7_dom

ARFGEF2 ARFGEF1

3.91e-03161102IPR000904
DomainPDEase

PDE1A PDE1B

5.51e-03191102IPR023088
DomainEGF_CA

MATN3 CUBN LRP1B VCAN

5.88e-031221104SM00179
PathwayREACTOME_CD22_MEDIATED_BCR_REGULATION

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

1.10e-16619413M27581
PathwayREACTOME_FCGR_ACTIVATION

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

6.22e-16699413M27108
PathwayREACTOME_SCAVENGING_OF_HEME_FROM_PLASMA

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

6.22e-16699413M27150
PathwayREACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

9.25e-16719413M1078
PathwayREACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

9.25e-16719413M27203
PathwayREACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

4.78e-15809413M6121
PathwayREACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

6.69e-15829413M27110
PathwayREACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

1.28e-14869413M601
PathwayREACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

1.28e-14869413M27206
PathwayREACTOME_FCERI_MEDIATED_MAPK_ACTIVATION

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

1.49e-14879413M27205
PathwayREACTOME_PARASITE_INFECTION

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11 NCKAP1L

2.94e-141169414M29843
PathwayREACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

4.88e-14959413M29842
PathwayREACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

7.40e-14989413M27152
PathwayREACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 MALT1 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

2.77e-131369414M27207
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11 NCKAP1L

5.58e-131439414M27107
PathwayREACTOME_COMPLEMENT_CASCADE

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

6.14e-131159413M19752
PathwayREACTOME_POTENTIAL_THERAPEUTICS_FOR_SARS

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IFNGR2 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

1.56e-121549414M39007
PathwayREACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 MALT1 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

4.37e-121669414M608
PathwayREACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

4.49e-121349413M29840
PathwayREACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 MALT1 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

2.06e-111869414M27175
PathwayREACTOME_LEISHMANIA_INFECTION

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11 NCKAP1L

1.83e-102199414M29836
PathwayREACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

3.72e-101909413M8240
PathwayREACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

4.82e-101949413M16312
PathwayREACTOME_SARS_COV_INFECTIONS

IGKV1-39 IGKV1-33 TPR IGKV1-17 IGKV1-16 IGKV1-12 ANO9 SEC24A IFNGR2 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

1.19e-084719417M39009
PathwayREACTOME_ADAPTIVE_IMMUNE_SYSTEM

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 FBXL13 SEC24A IGKV1-5 MALT1 ANAPC2 IGKV3D-20 GAN IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 DYNC1H1 IGKV3-11 DYNC1LI2 HERC5

8.72e-088289421M1058
PathwayREACTOME_VESICLE_MEDIATED_TRANSPORT

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 SEC24A SEC31B IGKV1-5 SYNJ1 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 DYNC1H1 IGKV3-11 DYNC1LI2

1.16e-067259418M27507
PathwayREACTOME_VIRAL_INFECTION_PATHWAYS

IGKV1-39 IGKV1-33 TPR IGKV1-17 IGKV1-16 IGKV1-12 ANO9 SEC24A IFNGR2 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 DYNC1H1 IGKV3-11 DYNC1LI2 HERC5

1.23e-068889420M48034
PathwayREACTOME_HEMOSTASIS

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 PDE1A ABCC4 PDE1B ITIH3 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 IGKV3-11

2.15e-066799417M8395
PathwayREACTOME_INNATE_IMMUNE_SYSTEM

IGKV1-39 HEXB IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 OLFM4 MUC16 IGKV1-5 MALT1 SERPINB12 IGKV3D-20 IGKV1D-39 MAPK11 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 DYNC1H1 IGKV3-11 HERC5 NCKAP1L

3.57e-0611289422M1036
PathwayREACTOME_INFECTIOUS_DISEASE

IGKV1-39 IGKV1-33 TPR IGKV1-17 IGKV1-16 IGKV1-12 ANO9 SEC24A IFNGR2 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-12 IGKV3-20 DYNC1H1 IGKV3-11 DYNC1LI2 HERC5 NCKAP1L

6.66e-0610819421M27548
PathwayREACTOME_ECM_PROTEOGLYCANS

COL6A3 MATN3 COL6A5 VCAN

2.66e-0447944MM14925
PathwayREACTOME_CAM_PDE_1_ACTIVATION

PDE1A PDE1B

6.48e-046942MM14494
Pubmed

Variation in the crossover point of kappa immunoglobulin gene V-J recombination: evidence from a cryptic gene.

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-17 IGKV1D-13

1.24e-22913296777049
Pubmed

Characteristics of the immunoglobulin Vkappa genes, pseudogenes, relics and orphons in the mouse genome.

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-13

2.51e-22201321110427970
Pubmed

Structure and implied functions of truncated B-cell receptor mRNAs in early embryo and adult mesenchymal stem cells: Cdelta replaces Cmu in mu heavy chain-deficient mice.

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-17 IGKV1D-13

1.38e-1816132917124007
Pubmed

IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes.

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-13 IGKV3-20

2.77e-18771321315608191
Pubmed

Human myeloperoxidase in innate and acquired immunity.

IGKV1-39 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-5 IGKV1D-39 IGKV1D-33 IGKV1D-13 IGKV1D-12

5.85e-1818132920399194
Pubmed

Amino acid sequence of the variable region of M149 mouse myeloma light chain: comparison with the nucleotide sequence of K2 and K3 clones.

IGKV1-39 IGKV1-13 IGKV1-9 IGKV1-5 IGKV1D-39 IGKV1D-33 IGKV1D-13

3.15e-151113276795447
Pubmed

Multiple related immunoglobulin variable-region genes identified by cloning and sequence analysis.

IGKV1-39 IGKV1-13 IGKV1-9 IGKV1-5 IGKV1D-39 IGKV1D-33 IGKV1D-13

3.15e-15111327279004
Pubmed

Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes.

IGKV1-39 IGKV1-13 IGKV1-9 IGKV1-5 IGKV1D-39 IGKV1D-33 IGKV1D-13

3.15e-151113276767723
Pubmed

The V kappa genes of the L regions and the repertoire of V kappa gene sequences in the human germ line.

IGKV1-17 IGKV1-12 IGKV3D-11 IGKV1D-17 IGKV1D-13 IGKV1D-12 IGKV3-11

1.82e-131713278223863
Pubmed

Evolutionary dynamics of the human immunoglobulin kappa locus and the germline repertoire of the Vkappa genes.

IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12

9.61e-1336132811298326
Pubmed

Clonal characterization of the human IgG antibody repertoire to Haemophilus influenzae type b polysaccharide. IV. The less frequently expressed VL are heterogeneous.

IGKV1-33 IGKV1-6 IGKV1D-33

5.34e-08313231940382
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 DCHS2 ACACB SPEG MATN3 NSUN7 GAN IGKV1D-39 IGKV1D-33 IGKV1D-16

6.10e-084971321336774506
Pubmed

A large section of the gene locus encoding human immunoglobulin variable regions of the kappa type is duplicated.

IGKV3D-11 IGKV1D-13 IGKV1D-12

2.13e-07413233927006
Pubmed

Organization and evolution of a gene cluster for human immunoglobulin variable regions of the kappa type.

IGKV1-13 IGKV1-12 IGKV1-9

5.31e-07513236086934
Pubmed

Primary structures of N-terminal extra peptide segments linked to the variable and constant regions of immunoglobulin light chain precursors: implications on the organization and controlled expression of immunoglobulin genes.

IGKV3D-20 IGKV3D-11 IGKV3-20

1.06e-066132398179
Pubmed

Mechanisms of antibody diversity: multiple genes encode structurally related mouse kappa variable regions.

IGKV3D-20 IGKV3D-11 IGKV3-20

1.06e-066132399744
Pubmed

Mouse immunoglobulin chains. Pattern of sequence variation among kappa chains with limited sequence differences.

IGKV3D-20 IGKV3D-11 IGKV3-20

1.06e-06613234691517
Pubmed

Recognition of immunoglobulins by Fcgamma receptors.

IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-33 IGKV3-20

1.10e-0648132511955599
Pubmed

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.

IGKV1-39 IGKV1-17 IGKV1-5 IGKV3D-11 IGKV1D-33 IGKV1D-12 IGKV3-20

1.32e-06143132722516433
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

PDXDC1 ACACB DSG2 SEC24A ARFGEF2 ARFGEF1 MUC16 CEP192 BIRC6 EFTUD2 ROBO1 AFDN DYNC1H1 DYNC1LI2

1.66e-067771321435844135
Pubmed

The 3' part of the immunoglobulin kappa locus of the mouse.

IGKV3D-20 IGKV3D-11 IGKV3-20

1.85e-06713239603450
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

IGKV1-39 HEXB IGKV1-17 DDAH2 COL6A3 CEL OLFM4 CUBN ITIH3 IGKV1-5 IGKV3D-11 ATIC IGKV1D-33 IGKV1D-12 IGKV3-20 DYNC1H1

3.22e-0610701321623533145
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DSG2 SEC24A CEP192 SYNJ1 N4BP2 GAN MACF1 AFDN AKAP13 TNKS1BP1 PLEKHM3 TRAPPC14 OTOG AHNAK2

5.39e-068611321436931259
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

IGKV1-39 IGKV1-33 TPR IGKV1-17 ADAR HMG20A EFTUD2 IGKV1-5 SERPINB12 IGKV1D-33 IGKV1D-12 IGKV3-20

7.69e-066521321231180492
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

TPR DSG2 IARS1 MACF1 TNKS1BP1 ATIC DYNC1H1 DYNC1LI2 AHNAK2

1.02e-05360132933111431
Pubmed

Functional and non-functional joining in immunoglobulin light chain genes of a mouse myeloma.

IGKV1-12 IGKV1D-12

1.43e-05213226776411
Pubmed

Variable region sequences of autoantibodies from mice with experimental systemic lupus erythematosus.

IGKV1-12 IGKV1D-12

1.43e-05213228325334
Pubmed

Isolation and differential tissue distribution of two human cDNAs encoding PDE1 splice variants.

PDE1A PDE1B

1.43e-052132211747989
Pubmed

Phage display of a human antibody against Clostridium tetani toxin.

IGKV1-39 IGKV1D-39

1.43e-05213227926831
Pubmed

Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex.

ARFGEF2 ARFGEF1

1.43e-052132223918382
Pubmed

The Double Mutation DSG2-p.S363X and TBX20-p.D278X Is Associated with Left Ventricular Non-Compaction Cardiomyopathy: Case Report.

DSG2 TBX20

1.43e-052132234202524
Pubmed

Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma.

ARFGEF2 ARFGEF1

1.43e-052132217360629
Pubmed

Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex.

ARFGEF2 ARFGEF1

1.43e-052132210716990
Pubmed

Membrane association of the Arabidopsis ARF exchange factor GNOM involves interaction of conserved domains.

ARFGEF2 ARFGEF1

1.43e-052132218203920
Pubmed

Cloning and characterization of 1116NS19.9 heavy and light chain cDNAs and expression of antibody fragments in Escherichia coli.

IGKV1-12 IGKV1D-12

1.43e-05213228372513
Pubmed

Purification and cloning of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors.

ARFGEF2 ARFGEF1

1.43e-052132210212200
Pubmed

Neuronal migration defects in the Loa dynein mutant mouse.

DNAH1 DYNC1H1

1.43e-052132221612657
Pubmed

Redundant roles of BIG2 and BIG1, guanine-nucleotide exchange factors for ADP-ribosylation factors in membrane traffic between the trans-Golgi network and endosomes.

ARFGEF2 ARFGEF1

1.43e-052132218417613
Pubmed

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.

HEXB CRYBG1 MACF1 AKAP13 DYNC1H1 NCKAP1L

1.86e-05143132630397336
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

DDAH2 ABCC4 DSG2 CEP192 BIRC6 PNPLA6 ANAPC2 ABCD4 ROBO1 MACF1 AFDN TARBP1

2.03e-057191321235337019
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

HEXB PPP4R1 DCHS2 ETS2 ARFGEF2 SEC31B LRP1B HMG20A SYNJ1 ROBO1 MACF1 AFDN TMEM131 ATIC TARBP1 DYNC1H1

3.09e-0512851321635914814
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

PDXDC1 HEXB PPP4R1 IARS1 SEC24A ARFGEF2 DNAJB4 ZZEF1 BIRC6 EFTUD2 MACF1 TNKS1BP1 EIF3A ATIC DYNC1H1 DYNC1LI2 AHNAK2

3.82e-0514551321722863883
Pubmed

140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry.

TPR PDE1A PDE1B BIRC6 DYNC1H1 DYNC1LI2

3.89e-05163132616512683
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

TPR BIRC6 PNPT1 PWP2 MACF1 UTP20 AFDN TNKS1BP1 ATIC DYNC1H1 HERC5

4.18e-056531321122586326
Pubmed

Interaction of phosphodiesterase 3A with brefeldin A-inhibited guanine nucleotide-exchange proteins BIG1 and BIG2 and effect on ARF1 activity.

ARFGEF2 ARFGEF1

4.28e-053132219332778
Pubmed

Specific functions of BIG1 and BIG2 in endomembrane organization.

ARFGEF2 ARFGEF1

4.28e-053132220360857
Pubmed

The TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathways.

INSIG1 EIF3A

4.28e-053132220068067
Pubmed

The proto-oncoprotein Brx activates estrogen receptor beta by a p38 mitogen-activated protein kinase pathway.

AKAP13 MAPK11

4.28e-053132211579095
Pubmed

Immunoglobulin genes of the kappa light chain type from two human lymphoid cell lines are closely related.

IGKV1-39 IGKV1D-39

4.28e-05313226091049
Pubmed

AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors.

ARFGEF2 ARFGEF1

4.28e-053132216866877
Pubmed

Receptor-mediated stimulation of lipid signalling pathways in CHO cells elicits the rapid transient induction of the PDE1B isoform of Ca2+/calmodulin-stimulated cAMP phosphodiesterase.

PDE1A PDE1B

4.28e-05313229003415
Pubmed

Systematic dissection of dynein regulators in mitosis.

DNAH1 DYNC1H1

4.28e-053132223589491
Pubmed

A C-terminal sequence in the guanine nucleotide exchange factor Sec7 mediates Golgi association and interaction with the Rsp5 ubiquitin ligase.

ARFGEF2 ARFGEF1

4.28e-053132218832381
Pubmed

Kinetic properties of Ca2+/calmodulin-dependent phosphodiesterase isoforms dictate intracellular cAMP dynamics in response to elevation of cytosolic Ca2+.

PDE1A PDE1B

4.28e-053132218335582
Pubmed

[Rule of antibody structure. The primary structure of a monoclonal immunoglobulin L-chain of kappa-type, subgroup 3 (Bence-Jones protein Ti). IV. The complete amino acid sequence and its significance for the mechanism of antibody production].

IGKV3D-20 IGKV3-20

4.28e-05313225027703
Pubmed

Molecular cloning and characterization of a calmodulin-dependent phosphodiesterase enriched in olfactory sensory neurons.

PDE1A PDE1B

4.28e-05313227568196
Pubmed

Peroxisome proliferator-activated receptor-delta induces insulin-induced gene-1 and suppresses hepatic lipogenesis in obese diabetic mice.

INSIG1 PPARD

4.28e-053132218627005
Pubmed

Involvement of BIG1 and BIG2 in regulating VEGF expression and angiogenesis.

ARFGEF2 ARFGEF1

4.28e-053132231199673
Pubmed

Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes.

PDE1A PDE1B

4.28e-053132217726023
Pubmed

Matrilin-3 inhibits chondrocyte hypertrophy as a bone morphogenetic protein-2 antagonist.

MATN3 BMP2

4.28e-053132225331953
Pubmed

Distinct functions for Arf guanine nucleotide exchange factors at the Golgi complex: GBF1 and BIGs are required for assembly and maintenance of the Golgi stack and trans-Golgi network, respectively.

ARFGEF2 ARFGEF1

4.28e-053132218003980
Pubmed

Enhancement of β-catenin activity by BIG1 plus BIG2 via Arf activation and cAMP signals.

ARFGEF2 ARFGEF1

4.28e-053132227162341
Pubmed

The Sec7 guanine nucleotide exchange factor GBF1 regulates membrane recruitment of BIG1 and BIG2 guanine nucleotide exchange factors to the trans-Golgi network (TGN).

ARFGEF2 ARFGEF1

4.28e-053132223386609
Pubmed

Immunoglobulin genes of different subgroups are interdigitated within the VK locus.

IGKV3D-11 IGKV3-11

4.28e-05313226440122
Pubmed

A crucial role for Arf6 in the response of commissural axons to Slit.

ARFGEF2 ARFGEF1 ROBO1

4.95e-0519132330674481
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

ARFGEF2 ARFGEF1 PNPLA6 AKAP13 TARBP1

4.97e-05104132531240132
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

HEXB ABCC4 DSG2 ARFGEF2 ARFGEF1 KIAA1549 DNAJB4 EXTL2 ZZEF1 LRP1B ROBO1 UTP20 TNKS1BP1 TMEM131 EIF3A

5.37e-0512011321535696571
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

TPR DSG2 ROBO1 TNKS1BP1 DYNC1H1 KNL1 AHNAK2

5.82e-05256132733397691
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

TPR ACACB DSG2 ADAR EFTUD2 SYNJ1 MACF1 TNKS1BP1 EIF3A ATIC HERC5 KNL1 AHNAK2

5.92e-059341321333916271
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

PDXDC1 IARS1 ZZEF1 DNAH1 EFTUD2 PACS2 MACF1 AKAP13 EIF3A ATIC DYNC1H1 AHNAK2

6.18e-058071321230575818
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

TPR ARFGEF2 SEC31B EFTUD2 ANAPC2 MACF1 TNKS1BP1 DYNC1H1 DYNC1LI2 KNL1

8.02e-055821321020467437
Pubmed

Evolution of immunoglobulin V genes: evidence indicating that recently duplicated human V kappa sequences have diverged by gene conversion.

IGKV1-16 IGKV1D-16

8.54e-05413226402305
Pubmed

Differences between germ-line and rearranged immunoglobulin V kappa coding sequences suggest a localized mutation mechanism.

IGKV1-12 IGKV1D-12

8.54e-05413226264318
Pubmed

Human NB-2 of the contactin subgroup molecules: chromosomal localization of the gene (CNTN5) and distinct expression pattern from other subgroup members.

ARFGEF2 ARFGEF1

8.54e-054132211013081
Pubmed

Interaction of FK506-binding protein 13 with brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1): effects of FK506.

ARFGEF2 ARFGEF1

8.54e-054132212606707
Pubmed

Isolation and characterization of genes associated with chromosome-6 mediated tumor suppression in human malignant melanoma.

CRYBG1 KNL1

8.54e-05413228700511
Pubmed

Protein kinase A-anchoring (AKAP) domains in brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BIG2).

ARFGEF2 ARFGEF1

8.54e-054132212571360
Pubmed

Effects of brefeldin A-inhibited guanine nucleotide-exchange (BIG) 1 and KANK1 proteins on cell polarity and directed migration during wound healing.

ARFGEF2 ARFGEF1

8.54e-054132222084092
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

TPR DSG2 IARS1 EXOSC8 ADAR EFTUD2 PNPLA6 SERPINB12 PWP2 CRYBG1 GAN UTP20 TNKS1BP1 EIF3A DYNC1H1

8.93e-0512571321536526897
Pubmed

Functional proteomics mapping of a human signaling pathway.

ETS2 ARFGEF2 PPARD ZZEF1 HMG20A ANAPC2 MACF1 AFDN DYNC1H1 KNL1

9.10e-055911321015231748
Pubmed

Extensive molecular differences between anterior- and posterior-half-sclerotomes underlie somite polarity and spinal nerve segmentation.

HEXB TPR ETS2 ROBO1

9.32e-0562132419463158
Pubmed

A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models.

EFTUD2 ANAPC2 DYNC1H1

1.02e-0424132333705438
Pubmed

Differential and restricted expression of novel collagen VI chains in mouse.

COL6A3 COL6A5

1.42e-045132221477648
Pubmed

Intracellular transport of human immunodeficiency virus type 1 genomic RNA and viral production are dependent on dynein motor function and late endosome positioning.

DNAH1 DYNC1H1

1.42e-045132219286658
Pubmed

The expanded collagen VI family: new chains and new questions.

COL6A3 COL6A5

1.42e-045132223869615
Pubmed

The human immunoglobulin kappa locus. Characterization of the duplicated O regions.

IGKV1-39 IGKV1D-39

1.42e-04513221907917
Pubmed

Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis.

BMP2 VCAN TBX20

1.46e-0427132323824573
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

TPR DSG2 IARS1 ADAR EFTUD2 SERPINB12 PWP2 MACF1 UTP20 AFDN EIF3A ATIC DYNC1H1

1.48e-0410241321324711643
Pubmed

Defining the membrane proteome of NK cells.

HEXB ABCC4 IARS1 ARFGEF2 ADAR BIRC6 EFTUD2 PNPLA6 AKAP13 EIF3A ATIC DYNC1H1 DYNC1LI2 NCKAP1L

1.48e-0411681321419946888
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

CEP192 HELB ROBO1 MACF1 TNKS1BP1 EIF3A

1.53e-04209132636779422
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

TPR IARS1 ADAR BIRC6 EFTUD2 PNPLA6 SERPINB12 MACF1 UTP20 AFDN AKAP13 EIF3A ATIC DYNC1H1 AHNAK2

1.99e-0413531321529467282
Pubmed

In vitro reconstitution of a highly processive recombinant human dynein complex.

DYNC1H1 DYNC1LI2

2.12e-046132224986880
Pubmed

Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction of GPR motifs with Gi alpha.

ROBO1 MACF1

2.12e-046132212719437
Pubmed

The human VK locus. Characterization of a duplicated region encoding 28 different immunoglobulin genes.

IGKV3D-20 IGKV3-20

2.12e-04613223351922
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

IARS1 EML6 ADAR MACF1 TNKS1BP1 DYNC1H1 AHNAK2

2.88e-04332132737433992
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

FBXL13 ETS2 CDH23 ADAR MACF1

2.96e-04152132534299191
Pubmed

Trim58 degrades Dynein and regulates terminal erythropoiesis.

DYNC1H1 DYNC1LI2

2.97e-047132225241935
Pubmed

The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice.

BMP2 MAPK11

2.97e-047132220551513
Pubmed

Three novel collagen VI chains with high homology to the alpha3 chain.

COL6A3 COL6A5

2.97e-047132218276594
Pubmed

Three novel collagen VI chains, alpha4(VI), alpha5(VI), and alpha6(VI).

COL6A3 COL6A5

2.97e-047132218400749
InteractionFBXO22 interactions

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 DCHS2 ACACB SPEG MATN3 NSUN7 EFTUD2 GAN IGKV1D-39 IGKV1D-33 IGKV1D-16

6.08e-0654012414int:FBXO22
Cytoband2p12

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

3.67e-28117132192p12
CytobandEnsembl 112 genes in cytogenetic band chr2p11

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

5.28e-2321313219chr2p11
GeneFamilyImmunoglobulin kappa locus at 2p11.2

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

3.33e-26839919351
CoexpressionSALVADOR_MARTIN_PEDIATRIC_TBD_ANTI_TNF_THERAPY_NONRESPONDER_POST_TREATMENT_DN

IGKV1-39 IGKV1-12 IGKV1-5 IGKV3-20 IGKV3-11

1.07e-08161285M41742
CoexpressionRASHI_RESPONSE_TO_IONIZING_RADIATION_6

IGKV1-39 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-5 IGKV1D-39 IGKV1D-33 IGKV1D-13 IGKV1D-12

1.82e-081321289MM996
CoexpressionSMID_BREAST_CANCER_RELAPSE_IN_PLEURA_DN

IGKV1D-39 IGKV1D-17 IGKV1D-13 IGKV3-20

1.75e-05321284M2118
CoexpressionGSE6259_CD4_TCELL_VS_CD8_TCELL_DN

PPP4R1 ADAR SYNJ1 VCAN PACS2 CRYBG1 TMEM131

3.47e-051841287M6739
CoexpressionAtlasAravindRamakr_StemCell-HD_top-relative-expression-ranked_1000_k-means-cluster#3

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 OLFM4 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11

6.23e-1118312513Arv_SC-HD_1000_K3
CoexpressionAtlasAravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500_k-means-cluster#2

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-12 IGKV1-9 OLFM4 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11

2.32e-1016312512Arv_SC-hpx_blastocyst_500_K2
CoexpressionAtlasAravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_500_k-means-cluster#3

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-12 IGKV1-9 OLFM4 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11

5.28e-1017512512Arv_SC-H9hpx_500_K3
CoexpressionAtlasAravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000_k-means-cluster#5

IGKV1-39 IGKV1-33 IGKV1-16 IGKV1-9 IGKV1-6 OLFM4 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11

8.83e-1018312512Arv_SC_fibroblast_1000_K5
CoexpressionAtlasAravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_1000_k-means-cluster#4

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-12 IGKV1-9 OLFM4 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11

2.26e-0824412512Arv_SC-H9hpx_1000_K4
CoexpressionAtlasAravindRamakr_StemCell-HD_top-relative-expression-ranked_500_k-means-cluster#2

IGKV1-39 IGKV1-33 IGKV1-17 OLFM4 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV3-20 IGKV3-11

5.86e-081261259Arv_SC-HD_500_K2
CoexpressionAtlasAravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500_k-means-cluster#3

IGKV1-39 IGKV1-33 IGKV1-17 OLFM4 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV3-20 IGKV3-11

1.37e-071391259Arv_SC_fibroblast_500_K3
CoexpressionAtlasAravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000_k-means-cluster#2

IGKV1-39 IGKV1-33 IGKV1-9 OLFM4 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11

4.03e-0626612510Arv_SC-hpx_blastocyst_1000_K2
CoexpressionAtlasAravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_500

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-12 IGKV1-9 OLFM4 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11 HERC5

6.85e-0649212513Arv_SC-H9hpx_500
CoexpressionAtlasAravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-12 IGKV1-9 OLFM4 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11 HERC5

6.85e-0649212513Arv_SC-hpx_blastocyst_500
CoexpressionAtlasAravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 OLFM4 KIRREL2 NSUN7 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11 HERC5

6.70e-0598612517Arv_SC_fibroblast_1000
CoexpressionAtlasAravindRamakr_StemCell-HD_top-relative-expression-ranked_1000

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 OLFM4 KIRREL2 NSUN7 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11 HERC5

6.70e-0598612517Arv_SC-HD_1000
CoexpressionAtlasAravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_1000

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-12 IGKV1-9 IGKV1-6 OLFM4 KIRREL2 NSUN7 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11 HERC5

2.25e-0498712516Arv_SC-H9hpx_1000
CoexpressionAtlasAravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-12 IGKV1-9 IGKV1-6 OLFM4 KIRREL2 NSUN7 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11 HERC5

2.25e-0498712516Arv_SC-hpx_blastocyst_1000
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

1.38e-2319513219f3f7f1a77a1edd2b50a8211c76fe289738eb04cf
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

1.69e-23197132199fe1b757f76c2d43d39aa9ac500eaba98723985c
ToppCellIPF-Lymphoid-B_Plasma|IPF / Disease state, Lineage and Cell class

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1-5 FER1L4 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

8.82e-2317613218e4f33f6cd140dd4fa3002bcd65ac8005d27865d1
ToppCellCOPD-Lymphoid-B_Plasma|World / Disease state, Lineage and Cell class

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-5 FER1L4 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV3-20 IGKV3-11

3.52e-2117513217d73ee324479172501481b54967a0f3bd870fcf3a
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 EML6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

5.21e-2117913217494febe77c6d4e6a2c6f0928bbf4c84b0301f188
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

2.10e-20194132176ef4aeb8d8e35e4df58ff2a8256caa2113291de9
ToppCellBiopsy_IPF-Immune-Plasma_cells|Biopsy_IPF / Sample group, Lineage and Cell type

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV3-20 IGKV3-11

2.51e-2019613217a1b6a8000b86efcb07843998aa3a49bb1f54bcda
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

2.51e-2019613217fec21383435779bf4c632decd3d29c6ca7baebfb
ToppCellControl-Lymphoid_P-Plasmablast|Control / Disease group, lineage and cell class

IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 EML6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

1.59e-19176132164b4416f342b732d2cc60133838728880326257d8
ToppCellControl-Lymphoid_P|Control / Disease group, lineage and cell class

IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 EML6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

1.59e-1917613216d895a6b295cd649273ff80ad7785a3e0ae4c728a
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-9 IGKV1-6 IGKV1-5 FER1L4 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-13 IGKV3-20 IGKV3-11

5.08e-19189132165a42be62552d912d0abf68f00d75ac80bbd69f2c
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

5.53e-191901321679ee6d10dfbb775da149a1104da5823cf63bbb46
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

5.53e-191901321618762ce78ed0b206ade19e1c8ff76a2647489f68
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

7.13e-191931321634f6c13884fdf7f8a87f942fcb36a58cfac3f65d
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_plasma|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-39 IGKV1-33 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

9.14e-1919613216c38e7f533c619afe008de0e99042f7180c2da918
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-6 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11 PARP15

9.93e-19197132162662138671262b30508c5759038bcdcfe6551696
ToppCellControl-Lymphoid-B_Plasma|Control / Disease state, Lineage and Cell class

IGKV1-39 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-5 RASSF6 FER1L4 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-13 IGKV3-20 IGKV3-11

4.27e-181721321561e33836b8cb0f347f3e699eb587a37073b6fa4c
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 EML6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

7.84e-1817913215837ed81f18257f444eaeadc4fac89deedd4e3061
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 EML6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

7.84e-1817913215b6ee4f41d8fb5f047b7bdd8489dda0a89fc6d43f
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgA_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

IGKV1-33 IGKV1-17 IGKV1-9 IGKV1-6 EML6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

1.40e-1718613215e2c050ba02e1f84f0b7258dc92e7ff6ab349ff67
ToppCellIPF-Lymphoid-B_Plasma|Lymphoid / Disease state, Lineage and Cell class

IGKV1-39 IGKV1-17 IGKV1-13 IGKV1-12 IGKV1-5 RASSF6 FER1L4 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-12 IGKV3-20 IGKV3-11

1.40e-1718613215f9c21daf905d0bb0e0e769ca4bb069ea4b1ba25b
ToppCell10x5'-GI_large-bowel|World / Manually curated celltypes from each tissue

IGKV1-39 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV3-20 IGKV3-11

1.10e-16168132141290c909655bc37f6b8bf216d18127a21b99e9c0
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 EML6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

2.31e-16177132144c434a7b7cc54cf4dac996bbc3f5124d9ef9a9cd
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 EML6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

2.31e-1617713214d746122bf8d208c3aa4d156e8c12d0a0e555c6e5
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 EML6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

2.31e-1617713214fc40918825b7e1eb6861df59dfca944778a64b98
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV3-20 IGKV3-11

3.69e-1618313214cf5c98f451a568308c52da5c926543dd4836c6b2
ToppCellhealthy_donor-Lymphocytic-Plasma_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

IGKV1-17 IGKV1-9 IGKV1-6 EML6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

5.39e-1618813214bd53b0371154cff680226897b61c9809a239d1b6
ToppCell5'-Adult-LargeIntestine-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV3-20 IGKV3-11

6.74e-1619113214d1d30279ed4612b4f62c225d9eabf0b8a7a09d11
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B-B_plasma|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-6 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

7.80e-1619313214282b47dae6043eabb1e13d41d91c07b5ec21cd65
ToppCellmetastatic_Brain-B_lymphocytes-MALT_B_cells|metastatic_Brain / Location, Cell class and cell subclass

IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

6.89e-151761321350e207403d48ce1b55a78897adb5519a2430a626
ToppCellIPF-Lymphoid-B_Plasma|World / Disease state, Lineage and Cell class

IGKV1-39 IGKV1-13 IGKV1-12 IGKV1-5 RASSF6 FER1L4 IGKV3D-20 IGKV3D-11 IGKV1D-33 IGKV1D-17 IGKV1D-12 IGKV3-20 IGKV3-11

6.89e-1517613213cc0cab6487df6867b529596ec94f55d31aa6ca36
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-17 IGKV1D-13 IGKV3-20 IGKV3-11

9.93e-1518113213e47664a264a2c37390d1668ce04eef2e0172f4cb
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

1.32e-141851321308bc817908076734d66f2805cb954141f2cc5a18
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

1.32e-14185132131704a12153a9b107bf03ecccd1a036cf61334d7a
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV1D-12 IGKV3-20 IGKV3-11

2.44e-1419413213a4a70369541876e1192df8828b63e3d1746ae3d9
ToppCellBiopsy_Other_PF-Immune-Plasma_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-13 IGKV3-20 IGKV3-11

2.61e-1419513213d0305c6a68c9e361507b04db94f86873085d49b3
ToppCellCOVID_vent-Lymphocytic-Plasma_cell-IgM_Plasmablast|COVID_vent / Disease condition, Lineage, Cell class and subclass

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 SEC24A IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV3-20 IGKV3-11

2.79e-1419613213026a06d8d2089806823e6f6453d3ede84ae93bc6
ToppCellnormal_Lung-B_lymphocytes-MALT_B_cells|normal_Lung / Location, Cell class and cell subclass

IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-13 IGKV3-20 IGKV3-11

6.03e-1415913212fbd0131b66f4267f7b0d6c3ad874ad097b859074
ToppCellControl-Lymphoid-B_Plasma|World / Disease state, Lineage and Cell class

IGKV1-39 IGKV1-13 IGKV1-12 IGKV1-5 RASSF6 FER1L4 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV3-20 IGKV3-11

1.35e-1317013212fb05f49b7113470995b3c16683c54dc1a660b73a
ToppCell(2)_Plasma_cells|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-6 IGKV1-5 RASSF6 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-16 IGKV3-20 IGKV3-11

2.18e-1317713212ed3c936bb69f9bc7291b4f6cde1d204078117c48
ToppCellCOPD-Lymphoid-B_Plasma|COPD / Disease state, Lineage and Cell class

IGKV1-39 IGKV1-17 IGKV1-13 IGKV1-12 IGKV1-5 RASSF6 FER1L4 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV3-20

2.18e-13177132121b872d3b1e0fca138362098590a634d748dfca60
ToppCell10x5'-Lung-Lymphocytic_B|Lung / Manually curated celltypes from each tissue

IGKV1-39 IGKV1-16 IGKV1-12 ARHGAP24 IGKV1-5 RASSF6 IGKV1D-39 IGKV1D-33 IGKV1D-12 IGKV3-20 IGKV3-11 PARP15

3.05e-1318213212310f94437d197eaaaf6e30e68063b33e94befe77
ToppCellcellseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IGKV1-39 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

3.25e-13183132125ab4aa0304b832f98fff89b6c24ad5b7dd014c11
ToppCell10x5'-Liver-Lymphocytic_B_plasma-Plasma_cells|Liver / Manually curated celltypes from each tissue

IGKV1-39 IGKV1-17 IGKV1-13 IGKV1-12 IGKV1-9 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

3.47e-13184132126f70d8f8ab8362d51f8a58735d42223e06566397
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-13 IGKV3-20 IGKV3-11

3.70e-13185132120fff2608f507e019ebb69c27e58fd5be3b049bef
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-33 IGKV1D-17 IGKV1D-13 IGKV3-20 IGKV3-11

3.70e-131851321279edc1eeb7b5b9123961ac3ecf398ee68d9dddb9
ToppCellCOVID_non-vent-Lymphocytic-Plasma_cell-IgG_Plasmablast|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-12 IGKV1-9 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-13 IGKV3-11

7.81e-1319713212b754fad4f3caae6de95df901fd96ea8697fe41b1
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 IGKV1-12 IGKV1-9 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-13 IGKV3-20 IGKV3-11

6.22e-1217813211107dae8b00c4257697a63700e72bb434cdb8406f
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 IGKV1-33 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

7.03e-1218013211e3877f6ef5f54ff689058b4c996ab1851822f871
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11

9.46e-12185132116ec009e48e50471c28e914c402f500e56a88f8f2
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11

9.46e-1218513211f49ad6401b2abd089e30eba245b11b5031ea2318
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-B_lymphocytic|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IGKV1-39 IGKV1-33 ARHGAP24 IGKV1-5 RASSF6 FER1L4 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11

1.13e-1118813211c3cae529fdbeb233d2b32bcc3537a8aba26a7dc2
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-9 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-13 IGKV3-20 IGKV3-11

1.13e-11188132116844cebca177fdf38b21a40d606230a033717a3a
ToppCellCOVID-19-Lymphoid-Plasma,_B_cells|COVID-19 / Condition, Lineage and Cell class

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-5 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV3-20 IGKV3-11 KNL1

1.50e-1119313211bffd97a73365e1dd23ff3b0320b4860f04ec091a
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-17 IGKV1D-13 IGKV3-20 IGKV3-11

1.58e-1119413211f083777353e76a2d9c39f8b6cb1a689b68b81c56
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-39 IGKV1-33 IGKV1-16 IGKV1-12 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-13 IGKV3-20

1.67e-111951321113f4ee21568fd747608412d33559d10561dbb3c8
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-6 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV1D-13 IGKV1D-12 IGKV3-11

1.67e-1119513211df009b18898c10686f75cf72b4ec0eff18f5bb50
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-39 IGKV1-16 IGKV1-12 ARHGAP24 IGKV1-5 IGKV3D-11 IGKV1D-39 IGKV1D-13 IGKV3-20 IGKV3-11 PARP15

1.87e-111971321188b29d205237f07a9a26cc15a1cf4ed4816a4c4b
ToppCellCOVID_non-vent-Lymphocytic-Plasma_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 SEC24A IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-13 IGKV3-20 IGKV3-11

1.87e-11197132111e63879633f20646e44873ae6b662f6faf4806fd
ToppCell368C-Lymphocytic-Plasma_cell-|368C / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-13 IGKV1D-12

5.92e-1116213210c21a54310b239d999bbc9d8fb5e8fda16e0bc336
ToppCell368C-Lymphocytic-Plasma_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-13 IGKV1D-12

5.92e-1116213210f945688815229c8386cbcbf46deee7df316fa8d3
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-9 IGKV1-6 ARHGAP24 LRP1B IGKV1-5 IGKV3D-20 IGKV1D-13 IGKV1D-12 IGKV3-20 PARP15

5.92e-1116213210b46158e260bd2f35702cec73e3b035e8e9ec4469
ToppCell367C-Lymphocytic-Plasma_cell-|367C / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-39 IGKV1-12 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-12 IGKV3-20 IGKV3-11

8.00e-1116713210f2185eb72f0137136f6d71af2a70168fded6c940
ToppCell367C-Lymphocytic-Plasma_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-39 IGKV1-12 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-12 IGKV3-20 IGKV3-11

8.00e-11167132105e768cf24699893e05d1bcb1c92dba2336943a64
ToppCellmetastatic_Brain-B_lymphocytes-Plasma_cells|metastatic_Brain / Location, Cell class and cell subclass

IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-17 IGKV3-20 IGKV3-11

9.53e-111701321053634da9e9c72f6400639954c286c6e38ea5a188
ToppCellPlasma_cells|World / lung cells shred on cell class, cell subclass, sample id

IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11

1.13e-101731321052a387e2a4694af61a9223a4c2ecf4e6f762c064
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-6 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV3-20 IGKV3-11

1.13e-10173132107e6bfe85f60834f317941b70d6e0dc3bd527d293
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 IGKV1-5 FER1L4 IGKV1D-39 IGKV3-20 IGKV3-11

1.42e-1017713210c2b0fb5921eea24d248d6e6ccb57c29b0832602c
ToppCellVE-plasma|VE / Condition, Cell_class and T cell subcluster

IGKV1-39 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-33 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

1.42e-10177132100c1cc0834de55717cb4f69d020339060ce2c9a03
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 IGKV1-5 FER1L4 IGKV1D-39 IGKV3-20 IGKV3-11

1.42e-1017713210111fb0707ff37ca631d85bb5a09e067ffe568eb8
ToppCellVE-plasma-|VE / Condition, Cell_class and T cell subcluster

IGKV1-39 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-33 IGKV1D-13 IGKV1D-12 IGKV3-20 IGKV3-11

1.42e-10177132103a3c94cf30012e2aa266bc4d7fe772e45fa90f6d
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells|lymph-node_spleen / Manually curated celltypes from each tissue

IGKV1-17 IGKV1-13 IGKV1-9 SEC24A IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12 IGKV3-20

1.97e-1018313210a6866951866373a1029e04818f4a4a31278c409d
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-lymphocytic-B_lymphocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-9 IGKV1-6 IGKV1-5 FER1L4 IGKV3D-11 IGKV3-20 IGKV3-11

2.84e-1019013210a21d0c574abf21e7cb865a21a48f29c92d055fbe
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-5 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV3-20

3.66e-10195132102d18f08f33f3b261c77b8adf87d1a184cc6d7400
ToppCell5'-Adult-LargeIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-13 IGKV3-20 IGKV3-11

3.66e-1019513210600174e35574fe7c44dd923adcf43686e7b01e39
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-16 IGKV1D-13 IGKV3-20

3.85e-1019613210b3d5540fe8ab9a9cbb9ab5350f5cb0e1aae93584
ToppCellBiopsy_Control_(H.)-Immune-Plasma_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

IGKV1-39 IGKV1-12 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV3-20 IGKV3-11

4.04e-1019713210275f38ed7e477000e864cecf9b7d49ae134c3b6a
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B-B_cell-B_mature|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-33 IGKV1-17 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV1D-33 IGKV1D-12 IGKV3-20 IGKV3-11 PARP15

4.04e-1019713210da175e66d0a743a1b91d46f224b5ff1d37aa5410
ToppCellmetastatic_Lymph_Node-B_lymphocytes-Plasma_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-5 IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV3-20 IGKV3-11

4.39e-1014213295ba3a33c2ee20be8baaed97536ca6e9d1de6752f
ToppCell390C-Lymphocytic-Plasma_cell-|390C / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-39 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 RASSF6 IGKV1D-33 IGKV1D-16 IGKV3-20

1.01e-0915613294f92ca30755430db44402afc603d1ecd8bfc3617
ToppCell390C-Lymphocytic-Plasma_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-39 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 RASSF6 IGKV1D-33 IGKV1D-16 IGKV3-20

1.01e-0915613290de2fc695bd5f8d4633c514f71ea941c88137bac
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-MALT_B_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-33 IGKV3-20

1.20e-091591329204e5a675f4684c9570c24c8d34bbf632fd8164a
ToppCellBAL-Mild-Lymphocyte-B|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-12 IGKV3-20

2.05e-091691329307571e57c3bfdf15f0fe1a8b36585e8e4f8a207
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell-B_activate-7|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-12 IGKV3-20

2.16e-091701329ee2ee67d90ae4596de8ccd620e37c82cf51651d4
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-12 IGKV3-20

2.16e-091701329d7ca0c6ce5d2b7de99346f87e07aa7fe728fa08a
ToppCellBAL-Mild-Lymphocyte-B-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-12 IGKV3-20

2.16e-09170132952787f6d529c285d9f0c04cc022710ead5b89b3f
ToppCellwk_08-11-Hematologic_Lymphocytic-B|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-13 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-13 IGKV3-11

2.40e-091721329d1ab8f493b70ec995281f9fb0991f1d3aa7b928f
ToppCell10x5'-bone_marrow-Lymphocytic_B_plasma-Plasma_cells|bone_marrow / Manually curated celltypes from each tissue

IGKV1-39 IGKV1-13 IGKV1-6 IGKV1-5 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV1D-13 IGKV3-20

2.52e-091731329300904fd35536a69be81d76fe33fe16544523ceb
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-17 IGKV3-20 IGKV3-11

3.57e-091801329cea079bc02e08c46600eed05ab9924ec90e1e3d3
ToppCellMild-Lymphoid-B|Mild / Condition, Lineage, Cell class and cell subclass

IGKV1-39 IGKV1-33 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV3-20

4.13e-0918313299b64d2d143525e6f48a191facfd101462ff36324
ToppCellMild-Lymphoid-B-|Mild / Condition, Lineage, Cell class and cell subclass

IGKV1-39 IGKV1-33 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV3-20

4.13e-091831329b5740f05a4dcdbbf24f7bf7a3f57ac01a5e75f60
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-16 IGKV3-20 IGKV3-11

4.33e-09184132915f2c10101ccc8ed059520fc082ee42593dff269
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-16 IGKV3-20 IGKV3-11

4.33e-091841329a90a58d9e319afa1cd572e4c2f516fadc42f56e5
ToppCell10x5'-Liver-Lymphocytic_B_plasma|Liver / Manually curated celltypes from each tissue

IGKV1-39 IGKV1-17 IGKV1-13 IGKV1-9 IGKV3D-20 IGKV1D-39 IGKV1D-13 IGKV3-20 IGKV3-11

4.76e-091861329a2c7430781f432c9c90ac4d620f4518ff767a223
ToppCellMild_COVID-19-B_cell-B_cell|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 IGKV1-5 IGKV3D-11 IGKV1D-39 IGKV3-20

4.76e-091861329855a5a00ba2aa1b5c63b8db56d026ddecc546050
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-12 ARHGAP24 IGKV1-5 IGKV1D-33 IGKV3-20 PARP15

7.85e-09197132976465bb2408c7c75f694e8f7cf1a606b796afc3a
ToppCellCOVID_vent-Lymphocytic-Plasma_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

IGKV1-39 IGKV1-9 SEC24A IGKV3D-20 IGKV3D-11 IGKV1D-39 IGKV1D-33 IGKV3-20 IGKV3-11

8.21e-091981329e84c5f712e1dea548d0e2aba6625598f9671d3a0
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_cell-B_mature|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-39 IGKV1-33 IGKV1-17 IGKV1-12 ARHGAP24 IGKV1-5 IGKV1D-39 IGKV3-20 PARP15

8.21e-091981329d51ee880acc5804cd918105fac846a1528333d6c
ToppCellControl-Control-Lymphocyte-B-Plasmablast|Control / Disease, condition lineage and cell class

IGKV1-39 IGKV1-17 IGKV1-9 EML6 IGKV1-5 IGKV3D-20 IGKV1D-39 IGKV3-20 IGKV3-11

8.58e-091991329c11aa8bca3723a886e7082ae48bb922dd8396be4
ToppCell10x5'-Lung-Lymphocytic_B-Naive_B_cells|Lung / Manually curated celltypes from each tissue

IGKV1-39 IGKV1-12 ARHGAP24 IGKV1-5 IGKV1D-39 IGKV1D-13 IGKV3-20 IGKV3-11

3.45e-0816513281776e7db80d7cf6b449fa8635a111705a59231b4
DiseaseCOMM domain-containing protein 1 measurement

IGKV1-17 IGKV1-16

1.59e-0521182EFO_0802424
Diseaselevel of nuclear factor NF-kappa-B p105 subunit in blood serum

IGKV1-17 IGKV1-16

1.59e-0521182OBA_2040323
Diseasecongenital muscular dystrophy (implicated_via_orthology)

COL6A3 DYNC1H1

2.35e-0461182DOID:0050557 (implicated_via_orthology)
Diseasealcohol dependence, risky sexual behaviour measurement

FSTL5 HMG20A

4.37e-0481182EFO_0007877, MONDO_0007079
Diseaselung cancer (implicated_via_orthology)

TPR ROBO1

5.60e-0491182DOID:1324 (implicated_via_orthology)
Diseaseliver fat measurement

OLFM4 RIOX2 RASSF6

6.85e-04431183EFO_0010821
DiseaseMarfan syndrome (implicated_via_orthology)

MATN3 BMP2

6.99e-04101182DOID:14323 (implicated_via_orthology)
Diseaseinterleukin-6 measurement, response to stimulus

FSTL5 MUC16

8.52e-04111182EFO_0004810, GO_0050896
DiseaseHypermetropia, Myopia

CEL CUBN PNPT1 CNTNAP5 TBX20

9.97e-041891185HP_0000540, HP_0000545
Diseasedisease recurrence, colon carcinoma

BMP2 ANAPC2 MACF1

1.13e-03511183EFO_0004952, EFO_1001950
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE (disorder)

CDH23 PNPT1

1.20e-03131182C1846647
DiseasePeripheral Nervous System Diseases

PPARD PNPLA6 GAN

1.33e-03541183C4721453
Diseaseinsulin metabolic clearance rate measurement, glucose homeostasis measurement

ZZEF1 HMG20A

1.40e-03141182EFO_0006830, EFO_0006896
Diseaseidiopathic pulmonary fibrosis

DNAJB4 AKAP13 KNL1

1.56e-03571183EFO_0000768
DiseaseProteinuria

CUBN FAM151B

1.61e-03151182HP_0000093
Diseasehepcidin:transferrin saturation ratio

EML6 MUC16

1.61e-03151182EFO_0007902
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

TRAPPC14 KNL1

1.83e-03161182DOID:0070296 (is_implicated_in)
Diseaseresponse to radiation, Urinary retention

COL6A3 LRP1B

2.07e-03171182GO_0009314, HP_0000016
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

PDXDC1 ACACB ITIH3 DNAH1 MACF1

2.11e-032241185EFO_0004530, EFO_0008317
Diseasefood allergy measurement, parental genotype effect measurement

DCHS2 EML6

2.33e-03181182EFO_0005939, EFO_0007016
Diseasecytomegalovirus virus reactivation, response to allogeneic hematopoietic stem cell transplant

PDE1A CDH23

2.59e-03191182EFO_0007044, EFO_0020106
Diseaseresponse to methotrexate, neurotoxicity

PNPLA6 MACF1

2.59e-03191182EFO_0011057, GO_0031427
Diseasemelanoma

PCDHB8 PPARD CUBN LRP1B CRYBG1

3.26e-032481185C0025202
DiseaseAutosomal Recessive Primary Microcephaly

TRAPPC14 KNL1

3.48e-03221182C3711387
Diseaseurate measurement, bone density

ARHGAP24 FSTL5 ETS2 COL6A5 HMG20A DNAH1 CNTNAP5 ROBO1

3.49e-036191188EFO_0003923, EFO_0004531
Diseaseaxial length measurement

HMG20A BMP2 ZNRF3

3.68e-03771183EFO_0005318
Diseasemean arterial pressure

PDE1A ARHGAP24 FBXL13 EML6 PPARD ZNRF3 ROBO1

4.00e-034991187EFO_0006340

Protein segments in the cluster

PeptideGeneStartEntry
LPASIEFRESSEDSF

AFDN

601

P55196
IEELFSIVRDFPDSR

ANAPC2

341

Q9UJX6
VELTRFETLTPRFSA

BIRC6

1026

Q9NR09
LDTSRIITESFFEVP

VCAN

1671

P13611
SVPEVFELSLSIFLT

ARFGEF1

496

Q9Y6D6
SAVLLVDETATTPIF

AKAP13

1876

Q12802
SSVPDVFELSLAIFL

ARFGEF2

446

Q9Y6D5
SVPVDSFFSLLTSER

ACAD10

116

Q6JQN1
TFDPSVVEIFLALSS

AASDH

241

Q4L235
EPADTAFLLERVSIS

ABCD4

381

O14678
LFSSSAVPFLEEQVT

ANO9

361

A1A5B4
DFETDVLFLVPTEIA

CEL

406

P19835
LSSIPTEEFITSAEL

BMP2

136

P12643
QPLDRETKSEFTVEF

CDH23

91

Q9H251
FDASRTDPTVLVFVE

NDST3

71

O95803
ETSIFIPAFESETKV

RASSF6

221

Q6ZTQ3
TSFAVFDDTLLIVDP

EXOSC8

196

Q96B26
LRPVTAFTLEATVDT

KIAA1549

921

Q9HCM3
FTLTISSLEPEDFAV

IGKV3D-11

91

A0A0A0MRZ8
LILSETTIFDVLPTF

ACACB

1266

O00763
LNVTSILDREETPFF

DSG2

111

Q14126
STTTLEVSQPFFIEI

OVOS1

671

Q6IE37
DTFTGEIPRVFTSSI

MUC16

5246

Q8WXI7
APETVVALFSVSDLD

PCDHB13

361

Q9Y5F0
STVLRLPVEAFSAVF

PNPLA6

291

Q8IY17
LTTVEVLSFSSITFP

PARP15

191

Q460N3
LLDVFTPATSIEDFS

MAPK11

86

Q15759
TDFTFTISSLQPEDI

IGKV1D-33

91

P01593
TDFTLTISSLQPEDF

IGKV1D-39

91

P04432
FPFLTSSERLEVVSR

HOGA1

81

Q86XE5
FITAFTVPDIDDVTV

LRP1B

1596

Q9NZR2
FIIDSSRSVRPLEFT

MATN3

86

O15232
VTFQVDTASDSPFLI

KCNJ10

236

P78508
TDFTLTISSLQPEDF

IGKV1D-12

91

P01611
DFTLTISRLEPEDFA

IGKV3D-20

91

A0A0C4DH25
ETTDEIPFSFSDRLR

MALT1

806

Q9UDY8
SLTAIPLEIFTFTEL

LRRIQ4

36

A6NIV6
KERSVFDIPIFTEEF

HMG20A

211

Q9NP66
ISLPAETELTVAVFD

FER1L4

1306

A9Z1Z3
TDFTLTISSLQPEDF

IGKV1D-13

91

A0A0B4J2D9
FAVSAESLPETLVIF

DYNC1LI2

121

O43237
DDTLISTPDLVFAFS

EXTL2

151

Q9UBQ6
IDFIVEPTFSLLTDS

PDE1A

421

P54750
DFIVEPTFSVLTDVA

PDE1B

426

Q01064
VEDELSSPVVVFRFF

PDXDC1

381

Q6P996
SLLDVQRVPSFESFE

ETS2

301

P15036
LDTVISFFPDVTFSL

FAM151B

151

Q6UXP7
VTLFPEEVIATIFSS

INSIG1

111

O15503
FVTPDTDIKVTLSIF

NCKAP1L

946

P55160
FPEFAERIEASLSEV

MACF1

141

O94854
TEFTLTISSLQPEDF

IGKV1D-17

91

A0A075B6S4
LTITFEESVVGFPFL

KNL1

2156

Q8NG31
TTTLEVSQPFFIEIA

OVOS2

771

Q6IE36
PEAEASTLDVFTERL

PACS2

391

Q86VP3
PALEVTEEFFSTLDS

PLEKHM3

11

Q6ZWE6
DRVDDFFIPTTTLII

FSTL5

596

Q8N475
AFLPSEAVEITEDSL

DCHS2

2346

Q6V1P9
RESEFALRPTFDLTV

HERC5

671

Q9UII4
TLFFPSAIERVSEAI

ABCC4

366

O15439
FSTFGELTVEPRRTE

ARHGAP24

726

Q8N264
IELKFSDFDVVPSTS

CUBN

3076

O60494
EDFTFVSLLTRPEVI

DNAH1

496

Q9P2D7
TTEALERTFLAFPAT

HBQ1

26

P09105
LIEFEVSFPDTISSS

DNAJB4

311

Q9UDY4
LTTFEAAPATEESLI

DRAXIN

191

Q8NBI3
DEIPRDFTTLFDLSI

IFT52

281

Q9Y366
SVSEDLLEPFIAVSA

ADAR

236

P55265
EFSRLTSLVPFVDAF

EIF3A

451

Q14152
FRDVSSTEEFLELSP

GAN

161

Q9H2C0
ALDISPTVFAFDERV

COL6A5

1891

A8TX70
ELEEIAFDSSLVFIP

COL6A3

591

P12111
FPERSSSEVFLVDET

FBXL13

136

Q8NEE6
IIRFSSPFDIADTST

IFNGR2

156

P38484
EDIFISVLFAPTRLS

CEP192

1836

Q8TEP8
TVDFEIATKEDPRSF

DYNC1H1

4621

Q14204
LEVVADASFLTEPVS

KIRREL2

276

Q6UWL6
TEFTLTISSLQPDDF

IGKV1-5

91

P01602
TDFTLTISSLQPEDF

IGKV1-6

91

A0A0C4DH72
TEFTLTISSLQPEDF

IGKV1-9

91

A0A0C4DH69
TDFTLTISSLQPEDF

IGKV1-12

91

A0A0C4DH73
TDFTLTISSLQPEDF

IGKV1-13

91

P0DP09
TDFTLTISSLQPEDF

IGKV1-16

91

P04430
TEFTLTISSLQPEDF

IGKV1-17

91

P01599
TDFTFTISSLQPEDI

IGKV1-33

91

P01594
TDFTLTISSLQPEDF

IGKV1-39

91

P01597
FTLTISSLEPEDFAV

IGKV3-11

91

P04433
DFTLTISRLEPEDFA

IGKV3-20

91

P01619
LERIFVVEFRPDSDT

EML6

1506

Q6ZMW3
SLRFIDVEFSEPTII

CRYBG1

1491

Q9Y4K1
IVADTFRDFAVSTVP

DDAH2

151

O95865
TFTINESTIIDSPRF

HEXB

186

P07686
LSSLFAAEVFPTVIR

SLC22A31

441

A6NKX4
TFIFVRLPEEDASSQ

HELB

696

Q8NG08
DFIRLEISSPSEITF

CNTNAP5

836

Q8WYK1
APETVVALFSVSDLD

PCDHB8

361

Q9UN66
TEDVAPADIVSFLLT

OTOG

1281

Q6ZRI0
FPEFFLTITSILETQ

UTP20

126

O75691
PAFDFVILLDVSDTS

SPEF2

776

Q9C093
ESDVIIIPSALDFVS

PPP4R1

26

Q8TF05
TVRELTEFAKSIPSF

PPARD

256

Q03181
FRVTSTEFISLRIDS

SYNJ1

96

O43426
ELDTPESARIIAFIS

SEC24A

1026

O95486
EVSFDVELPKTAFIT

ITIH3

76

Q06033
FLSILTRERDPSETV

NSUN7

501

Q8NE18
SLEVEPFASLTEAVR

SIRT3

321

Q9NTG7
LERALDATEVPFSIT

TEKT4

126

Q8WW24
VFVTFPLEEDETVSL

IARS1

206

P41252
PRLVFISQVTTESEF

SEC31B

416

Q9NQW1
FPFTIRVTSEVLESN

PNPT1

466

Q8TCS8
DTTFPVDRVERLEFT

OLFM4

91

Q6UX06
SEESVVLSFPRFTLE

SERPINB12

291

Q96P63
EFVDLSVPRTFSTQI

AHNAK2

5486

Q8IVF2
FTLFLETVEPVAVES

C10orf126

71

Q8N4M7
PLTFRDVAIEFSLEE

ZNF273

36

Q14593
SVTLELAEAPRFESI

SPEG

1476

Q15772
STDEVIFPLTVSLDR

TRAPPC14

146

Q8WVR3
FFDDEDRTVPSTPTL

TPR

2126

P12270
DTRVLFDPFELDTSV

PWP2

731

Q15269
PASERFAATTVEEIL

TNKS1BP1

151

Q9C0C2
SRDIIILFTPDFTAS

TMEM131

1061

Q92545
SEVAELTVLERPSFV

ROBO1

251

Q9Y6N7
LTEVSISSDAFFPFR

ATIC

531

P31939
LFESLISPIKTETFF

RIOX2

41

Q8IUF8
FETIVSALDELDIPF

ZNF862

671

O60290
TFLSPNVLEEVDSFL

ZZEF1

446

O43149
KETAFVEVVLFESSP

ZNRF3

56

Q9ULT6
LKSEEFRTFIFPETV

TBX20

246

Q9UMR3
TIDKFTRFTDVPLAA

TARBP1

1376

Q13395
PTSSSQRSFVEFILE

EFTUD2

361

Q15029
FTTFELFLTVIDAPA

TRPV5

531

Q9NQA5
GPLTFRDVTIEFSLE

ZNF729

11

A6NN14
TDFTLTISSLQPEDF

IGKV1D-16

91

P01601
FTSISEIFSDLDPDV

N4BP2

51

Q86UW6