Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoenlarged adenohypophysis

TCF7L2 LATS1

1.75e-055192MP:0008366
DomainZnF_U1

ZFHX3 ZNF318

5.77e-0429232SM00451
DomainZnf_U1

ZFHX3 ZNF318

5.77e-0429232IPR003604
DomainSH3_9

TSPOAP1 ARHGAP33

4.12e-0378232PF14604
DomainSH3_2

TSPOAP1 ARHGAP33

4.98e-0386232IPR011511
DomainSH3_2

TSPOAP1 ARHGAP33

4.98e-0386232PF07653
Pubmed

WWP1 E3 ligase targets LATS1 for ubiquitin-mediated degradation in breast cancer cells.

WWP1 LATS1

4.56e-07224223573293
Pubmed

NEDD4 E3 ligase inhibits the activity of the Hippo pathway by targeting LATS1 for degradation.

WWP1 LATS1

3.00e-051224224107629
Pubmed

Deubiquitylase USP9X suppresses tumorigenesis by stabilizing large tumor suppressor kinase 2 (LATS2) in the Hippo pathway.

USP9X LATS1

4.13e-051424229183995
Pubmed

ARRDC1 and ARRDC3 act as tumor suppressors in renal cell carcinoma by facilitating YAP1 degradation.

USP9X WWP1

9.51e-052124229416926
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

ACHE ZFHX3 ZNF318 TCF7L2 TBX21

1.07e-0470924522988430
Pubmed

Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway.

USP9X LATS1

1.47e-042624228720576
Pubmed

The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development.

ZFHX3 TCF7L2

1.71e-042824232868762
Pubmed

Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.

ZFHX3 TCF7L2

3.33e-043924221347282
Pubmed

Citron kinase interacts with LATS2 and inhibits its activity by occluding its hydrophobic phosphorylation motif.

USP9X LATS1

3.50e-044024230865227
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

USP9X CCDC34 WWP1 ZNF318 CHERP

3.62e-0492224527609421
Pubmed

Multidimensional Proteomics Reveals a Role of UHRF2 in the Regulation of Epithelial-Mesenchymal Transition (EMT).

TCF7L2 CHERP

6.63e-045524227114453
ToppCellcellseq2-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-NK|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LY6G5C DRAXIN TBX21 CD6

2.58e-061822448ccffcbae28c374fd4161fb0d4cf2c49fae557f6
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-iNKT-MAIT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GLB1L TBX21 CD6

5.69e-05140243a8f3b01d03ee0bf0e752327a98d6b9035930c2b0
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSPOAP1 ARHGAP33 TBX21

7.41e-051532430727dc70e16345645063c586d744bc4ac1710526
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC34 NAALAD2 TMEM200B

7.99e-05157243410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CCDC34 ARHGAP33 TBX21

8.30e-051592432233fee5dcdb6c7dee5b1bd8efbc07d86b339927
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DRAXIN TBX21 CD6

9.26e-051652438dbd03795fff060cd2e4d5d97348f5b63515e030
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DRAXIN TBX21 CD6

9.26e-051652435fc5e34cc805df44c020256729256ef761790152
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DRAXIN TBX21 CD6

9.26e-0516524364c7c45383afde1d050934938705e47aa615755f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DRAXIN TBX21 CD6

9.77e-05168243318fa1bd5a9d6ae95042517ef30515b6416b61e4
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DRAXIN TBX21 CD6

9.77e-0516824375b3998aff704a77895ee3723813d8a3819b7cec
ToppCellControl-Epithelial_alveolar-Mes-like-AT1_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACHE CCDC34 ZNF318

9.77e-0516824349180994311b3f4f9ec338b1d35d8edd7422e3c9
ToppCellControl-Epithelial_alveolar-Mes-like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACHE CCDC34 ZNF318

9.77e-051682433c2ce9cfaca8ceab9b29f918ab46afc69eba3330
ToppCellfacs-SCAT-Fat-18m-Lymphocytic-T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP33 TBX21 CD6

9.94e-05169243700a3a36c379872585204caa6a6cc269b036ae22
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACHE NPR1 WWP1

9.94e-05169243780fb0050852626062a729dd1b82b0cf61e7e9ca
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TEX13C TSPOAP1 TBX21

1.10e-0417524363e977b8bafae1c5f742fc35a4cc712fefa9727f
ToppCelldroplet-Marrow-BM-30m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACHE TBX21 CD6

1.14e-04177243d1af0cb4b1fb03f04cff5add85e29be8fb8f4dcb
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-mature_NK_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WWP1 TBX21 CD6

1.14e-04177243dba8b30a311051c22ca5f77697f5dbf9423c3ba0
ToppCelldroplet-Marrow-BM-30m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACHE TBX21 CD6

1.14e-04177243650095a17e1a39caea74a6e89646565b9332af5d
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|368C / Donor, Lineage, Cell class and subclass (all cells)

ACHE WWP1 ARHGAP33

1.18e-04179243ec69e1dd897414033ba5b007aa82655a79adca6c
ToppCellAdult-Immune-natural_killer_cell-D175|Adult / Lineage, Cell type, age group and donor

DRAXIN TBX21 CD6

1.20e-04180243fc59e28f39e7d4fb1bcc7205202cf39224b70d7b
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ACHE WWP1 ARHGAP33

1.32e-04186243799903b68bc6f6205d004b44c603424b0d5f7c32
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ZFHX3 NAALAD2 TCF7L2

1.41e-041902437986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

DRAXIN ZFHX3 FAM222A

1.41e-04190243842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX3 NAALAD2 TMEM200B

1.43e-04191243cb75e6c36dbe2e091e407d691c063ec7c4fd5f90
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX3 NAALAD2 TMEM200B

1.43e-04191243b2cffea7860dd590b505ee0ebd51aa1978cb5e64
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX3 NAALAD2 TMEM200B

1.45e-04192243e5117cdb8af220f60bd1410262078c0306667b4a
ToppCell(200)_CD56+_NK_cell|World / immune cells in Peripheral Blood (logTPM normalization)

DRAXIN TSPOAP1 TBX21

1.59e-04198243459e841a01a900808707140297c89c1d6a79024f
ToppCellhealthy_donor-Lymphocytic-ILC-NK_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

DRAXIN TSPOAP1 TBX21

1.59e-04198243d7053a898e04478c577381085f615edaad3cdc5b
ToppCellmild_COVID-19_(asymptomatic)-NK|World / disease group, cell group and cell class (v2)

DRAXIN TSPOAP1 TBX21

1.59e-041982437a0aac52d785037455e068e1b25de4b2bf0fff79
ToppCellhealthy_donor-Lymphocytic-ILC|healthy_donor / Disease condition, Lineage, Cell class and subclass

DRAXIN TSPOAP1 TBX21

1.59e-04198243aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCell(20)_NK_cell|World / immune cells in Peripheral Blood (logTPM normalization)

DRAXIN TSPOAP1 TBX21

1.59e-04198243178b885e56e734a4408032ea79c68163333de9b6
ToppCellBiopsy_Other_PF-Immune-Proliferating_T_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

CCDC34 TBX21 CD6

1.61e-041992431d55d06e658939b78ea046553757821381eaa026
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)|Hippocampus / BrainAtlas - Mouse McCarroll V32

NAALAD2 TMEM200B

1.08e-039124278e2e65beb15bf1e251974c72fbcfab817492772
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

NAALAD2 TMEM200B

1.08e-0391242f59908093416ca7b3ca27019d71c79acbdea18cb
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

NAALAD2 TMEM200B

1.08e-0391242104d2ab9fe5cc404388c32fafb34e421c2e138be
ToppCelldroplet-Fat-Scat-21m-Hematologic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACHE TMEM200B

1.11e-0392242246aebf5f17d50f67a7b48f713ea5043cefefb24
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Rassf10|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LY6G5C TCF7L2

1.18e-03952420ac6cba7e0ed6083f777287f39a871461fa1bca4
ToppCelldroplet-Fat-Scat-21m-Hematologic-erythroblast|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACHE TMEM200B

1.23e-03972426fff45d4c4bbd81a67e1ad12b131cfe6a5ab37e6
ToppCelldroplet-Fat-Scat-21m-Hematologic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACHE TMEM200B

1.23e-0397242440d45ecfc9b66cb61d734118601e745892d51e3
ToppCellControl-B_naive-4|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DRAXIN NAALAD2

1.41e-031042425f72aa686b0fb83d401621e1b9d9c69e56105570
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-Kcnj8|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NAALAD2 TMEM200B

1.66e-031132420651fb7a7e1ea84b8365059e5ed85bf6c082da1a
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-Kcnj8-MURAL_Mural.Acta2Rgs5.Kcnj8-Abcc9_(Mural.Acta2Rgs5.Kcnj8-Abcc9)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NAALAD2 TMEM200B

1.66e-031132420e153efddd061d7510dfc3859cc8b1a7984fa70e
ToppCellSubstantia_nigra|World / BrainAtlas - Mouse McCarroll V32

ZFHX3 TCF7L2

1.72e-0311524218174b8d57d444fab1e9d2b13d22939c83c958e0
ToppCellThalamus|World / BrainAtlas - Mouse McCarroll V32

ZFHX3 TCF7L2

1.75e-031162425ddfb2dd5459ff6d7ae38163a38eae64fda283b7
ToppCellSevere-B_naive-13|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FAM222A ZNF318

1.75e-03116242f81a7c3e9cbf39124232d98e2a3a3e308137f391
ToppCellControl-B_naive-4|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DRAXIN NAALAD2

1.75e-0311624235d471c8dbf408d0be3837c428d9c2a73c805a6f
ToppCellSevere-B_naive-13|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FAM222A ZNF318

1.87e-03120242d08edc09de8497714af55a6ca08a447cd71095e7
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic-3|TCGA-Mesothelium / Sample_Type by Project: Shred V9

TGM7 NAALAD2

2.09e-03127242df2854bcb2708ddc13b3ca48c03887380e827790
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NAALAD2 CD6

2.33e-031342423b67c02b430b6d58467f36e606c478d3eea0063f
ToppCellCOVID-19_Severe-Classical_Monocyte-|Classical_Monocyte / Disease condition and Cell class

TBX21 CD6

2.40e-03136242e272d11bb52f890f6681cc9384aeac27976ec650
ToppCellTracheal-10x5prime-Immune_Lymphocytic-T-T_CD8-gdT|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DRAXIN TBX21

2.47e-03138242769be787e24532d5e023f99f82c7272bddac40c3
ToppCellCOVID-19_Severe-Classical_Monocyte-|COVID-19_Severe / Disease condition and Cell class

TBX21 CD6

2.54e-03140242cade44740dd3acca7789591aa5a7935d48d5cbee
ToppCellSevere-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

NAALAD2 ZNF318

2.54e-03140242683ee5e103f0c68cbbec019249404d381dbc39f3
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LY6G5C TGM7

2.61e-03142242759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCellTCGA-Brain-Recurrent_Tumor|TCGA-Brain / Sample_Type by Project: Shred V9

TMEM200B TBX21

2.64e-03143242eeb8ce6e051e18b82b74aaf2fc23f0cb87fc96d5
ToppCellControl-Myeloid-Dendritic_cells-pDC|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DRAXIN GLB1L

2.72e-03145242bab85a72142b6257f7d424e5301f65b6dcdf745d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LY6G5C TCF7L2

2.75e-031462421e81ad3d6d5d5ad2f0176d2a9593a954d38fa294
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CCDC34 NAALAD2

2.79e-03147242c0f62ed3312a33921476e89844486e09326485b7
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-MAIT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBX21 CD6

2.87e-03149242f4bee5fdaaa4a1917e403de90e5a62353006df24
ToppCell356C-Lymphocytic-NK_cells-NK_cell_C|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DRAXIN TBX21

2.87e-0314924295b21d67d6c335330a508f78d5cc074fdaf92275
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

GLB1L ZNF318

2.90e-03150242744050a1b665c6989f37141348af3df7579a73c9
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|368C / Donor, Lineage, Cell class and subclass (all cells)

DRAXIN CD6

2.90e-03150242c843bcf98c5fad2ca4339602f721f3fb782ae353
ToppCellPND07-28-samps-Mesenchymal-Pericyte|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ACHE NAALAD2

2.90e-031502425b111ec11a642d63fafa7e1422e36f81a2776531
ToppCellPND07-28-samps-Mesenchymal-Pericyte-pericyte_F|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ACHE NAALAD2

2.90e-031502422d0d6dc07dcfe28e3d7694c52d15d17dae2fd47b
ToppCellLPS_only-Lymphocytic_NKT-iNKT/MAIT-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSPOAP1 TBX21

2.94e-031512427270b8bbfae659e110bd9d513b602120b25de3dd
ToppCellFrontal_cortex-Endothelial-MURAL|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NAALAD2 TMEM200B

2.94e-031512427570372a315bc312ff57bb5f483375c401ae8787
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NAALAD2 TMEM200B

2.94e-03151242527059e47e381b2f6d63c1abb39bc0795ee3829d
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell|368C / Donor, Lineage, Cell class and subclass (all cells)

TBX21 CD6

2.94e-03151242512f7f37ddc8dfa1906f7fff92b571929236c9ea
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAM222A ZNF318

2.94e-03151242f41c6558a5874b6464c157027fdf202257c60e5b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 NAALAD2

2.98e-031522420cb5f4dfae04e3f4eba502bbf229007d5fa3884d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 NAALAD2

2.98e-03152242ba89ffb5a8bb33c188f854f54b39123b6d73496a
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP33 CD6

3.02e-03153242c4dcdcaa672929c1da870e9fb8ada1bb030ad12f
ToppCellLeuk-UTI-Lymphocyte-T_NK-CD4_CTL|Leuk-UTI / Disease, Lineage and Cell Type

TBX21 CD6

3.06e-03154242170a421fd69dba2929568c72e983ae9cfaf2aabc
ToppCellfacs-Heart-RA-24m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX21 CD6

3.10e-03155242cc3fc379ea78742a216317054f336331f7c7a157
ToppCellfacs-Heart-RA-24m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX21 CD6

3.10e-031552421900a76754e2a9c7117e531c5907b7942f72c4a6
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LY6G5C TMEM200B

3.14e-03156242e388ca0619318779389e3d66397a294e5251bf04
ToppCellPND07-28-samps-Lymphocyte-T_cells|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TBX21 CD6

3.18e-03157242f3b4cde52423246ae6fc4924cd1ee502cf6c009c
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPOAP1 GLB1L

3.18e-03157242c779a53b2c67d566f5d417e753cd17196a6bfd1c
ToppCellfacs-Spleen-nan-18m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX3 TBX21

3.18e-03157242a84377028c661f8f3ecae0f6082abdd859faf0c8
ToppCellfrontal_cortex-Non-neuronal-smooth_muscle_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZFHX3 TMEM200B

3.21e-0315824208806240228c5b780f5aef92ce2c278ae4d797cc
ToppCellHippocampus-Endothelial-MURAL|Hippocampus / BrainAtlas - Mouse McCarroll V32

NAALAD2 TMEM200B

3.21e-031582422d73b5e59c650c603fec6223b1c51f0962f7bc81
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|368C / Donor, Lineage, Cell class and subclass (all cells)

TBX21 CD6

3.21e-03158242390b9c455ed15a6804613eecfd2776949dfba146
ToppCellfrontal_cortex-Non-neuronal-smooth_muscle_cell-SMC-SMC_Acta2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZFHX3 TMEM200B

3.21e-03158242496b6988f7b3439968351840ae22f56ffa1643f1
ToppCellfrontal_cortex-Non-neuronal-smooth_muscle_cell-SMC|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZFHX3 TMEM200B

3.21e-031582425b3d30f92b619f14a7b48502170000fa5783358a
ToppCellCOVID-19-APC-like-Monocytes|COVID-19 / group, cell type (main and fine annotations)

TSPOAP1 ACHE

3.21e-03158242a0d94bd067424783863a48db20976d4c2043600c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TEX13C CD6

3.21e-031582425775246e192629058ed89fb56031bdf4cbb9c15c
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|367C / Donor, Lineage, Cell class and subclass (all cells)

TSPOAP1 TBX21

3.21e-03158242c08b5e12cc2975e52965e22ec987d0d45a9a68e9
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

NAALAD2 TMEM200B

3.21e-031582427f4a644534b78f7e7539cae1fd895dad6f96862b
ToppCellSevere-B_naive-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

NAALAD2 ZNF318

3.25e-031592422881b054bbeb479221ee3c38bbd9b0815b123579
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LY6G5C ARHGAP33

3.25e-03159242c960df9e4fa980401941866b5081facac4590b4d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TBX21 CD6

3.29e-031602421a9329d8183296f36928bd9e96f10db9f04ce326
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX21 CD6

3.29e-031602429e238e7cb31070a5b9da73b4bfddde54b969b0fd
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX21 CD6

3.29e-03160242c0f37057ff073c0578c5236ab5b5f4c9fe2d6224
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBX21 CD6

3.29e-03160242ec81814f3a475ba9bc049cb793bf93bc0b650d37
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX21 CD6

3.29e-031602423a5a7984d9ffcb0fbada02b95ffd7aca091acf30
ToppCell368C-Myeloid-Dendritic-cDC_activated|368C / Donor, Lineage, Cell class and subclass (all cells)

TSPOAP1 ACHE

3.29e-03160242bcd90ef96464bd901b87b94c696de70c113bfd03
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX21 CD6

3.29e-0316024232a105b99fc565c944672f518d6947dcf9ea8832
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX21 CD6

3.34e-03161242334f540dff3508d451e5e85e8e4e8f3b8d6b74e7
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DRAXIN ACHE

3.34e-0316124252556b89808e551540f33a13f57417a6696c2438
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSPOAP1 WWP1

3.34e-031612428937f6b92cb2a93ea8c4780d9200a518c3112e53
ComputationalGenes in the cancer module 445.

ACHE NPR1

2.44e-0415172MODULE_445
DrugN-methylpiperidin-4-yl propionate

TSPOAP1 ACHE

2.23e-057242CID000133349
Drug(+,-)-Octopamine hydrochloride [770-05-8]; Down 200; 21uM; PC3; HT_HG-U133A

ZFHX3 LATS1 CD6 DIMT1

4.66e-051932445050_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A

TSPOAP1 TCF7L2 DIMT1 MSL3

4.66e-051932442949_DN
DrugAcetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A

TSPOAP1 GLB1L NAALAD2 MSL3

4.75e-051942442223_UP
DrugFlorfenicol [73231-34-2]; Down 200; 11.2uM; PC3; HT_HG-U133A

ZFHX3 NAALAD2 CD6 MSL3

4.85e-051952446701_DN
DrugPiracetam [7491-74-9]; Up 200; 28.2uM; MCF7; HT_HG-U133A

NPR1 GLB1L NAALAD2 ARHGAP33

4.85e-051952442861_UP
DrugSulfachloropyridazine [80-32-0]; Down 200; 14uM; PC3; HT_HG-U133A

ZFHX3 ARHGAP33 CD6 DIMT1

4.85e-051952444326_DN
DrugBicuculline (+) [485-49-4]; Down 200; 10.8uM; PC3; HT_HG-U133A

NAALAD2 ARHGAP33 CD6 DIMT1

4.95e-051962444574_DN
Drugprednisolone; Down 200; 1uM; MCF7; HG-U133A

GLB1L ARHGAP33 CD6 CHERP

4.95e-05196244265_DN
DrugCiprofloxacin hydrochloride [93107-08-5]; Down 200; 10.8uM; PC3; HT_HG-U133A

NAALAD2 CD6 DIMT1 MSL3

5.04e-051972446700_DN
DrugMethimazole [60-56-0]; Up 200; 35uM; PC3; HT_HG-U133A

NAALAD2 LATS1 TBX21 CD6

5.04e-051972443815_UP
DrugLevodopa [59-92-7]; Up 200; 20.2uM; MCF7; HT_HG-U133A

TSPOAP1 NPR1 LATS1 CD6

5.04e-051972444394_UP
DrugNimesulide [51803-78-2]; Down 200; 13uM; MCF7; HT_HG-U133A

ZNF318 TCF7L2 CD6 DIMT1

5.04e-051972442275_DN
DrugPhenethicillin potassium salt [132-93-4]; Down 200; 10uM; HL60; HT_HG-U133A

ZFHX3 LATS1 CD6 MSL3

5.14e-051982442542_DN
DrugOxaprozin [21256-18-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A

NAALAD2 LATS1 CD6 DIMT1

5.14e-051982443876_UP
DrugChloroquine diphosphate [50-63-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A

ZFHX3 ZNF318 CD6 DIMT1

5.14e-051982447012_UP
DrugGriseofulvin [126-07-8]; Up 200; 11.2uM; HL60; HT_HG-U133A

TSPOAP1 TCF7L2 DIMT1 MSL3

5.14e-051982442332_UP
DrugAceclofenac [89796-99-6]; Down 200; 11.2uM; MCF7; HT_HG-U133A

ZNF318 TCF7L2 CD6 DIMT1

5.14e-051982442281_DN
DrugEthosuximide [77-67-8]; Up 200; 28.4uM; PC3; HT_HG-U133A

NPR1 GLB1L ARHGAP33 CD6

5.35e-052002442116_UP
Drug78 h

NAALAD2 LATS1

1.11e-0415242CID000095054
Drugtriphenyl phosphite

TSPOAP1 ACHE

1.61e-0418242CID000007540
DrugSperact

NPR1 CD6

2.90e-0424242CID000123688
DrugAC1L1D63

TSPOAP1 NAALAD2

3.15e-0425242CID000002209
DrugSchiff's reagent

ACHE LATS1

3.41e-0426242CID000010484
Drugginsenoside Re

NPR1 TBX21

3.96e-0428242CID000073149
Drugpirimiphos-methyl

ACHE LATS1

4.25e-0429242CID000034526
Druglinalool

ACHE CD6

4.25e-0429242CID000006549
Drugp-nitrophenyl

ACHE GLB1L LATS1

4.74e-04146243CID000007416
Drug6-aminonicotinamide

ACHE NPR1

7.71e-0439242CID000009500
DrugBNPP

ACHE LATS1

8.11e-0440242CID000000255
Drug1-(3-pyridyl)-1-butanone

ACHE TGM7

8.94e-0442242CID000459502
DrugGBR 12909 dihydrochloride [67469-78-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A

NPR1 NAALAD2 CD6

9.72e-041872433240_UP
DrugEpivincamine [6835-99-0]; Up 200; 11.2uM; PC3; HT_HG-U133A

TSPOAP1 LATS1 DIMT1

1.00e-031892434500_UP
DrugPhenacetin [62-44-2]; Up 200; 22.4uM; MCF7; HT_HG-U133A

GLB1L TCF7L2 MSL3

1.00e-031892432832_UP
DrugFenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; PC3; HT_HG-U133A

ZFHX3 ARHGAP33 CD6

1.02e-031902434274_UP
DrugPramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; PC3; HT_HG-U133A

GLB1L ARHGAP33 DIMT1

1.03e-031912433811_DN
Diseaseheart failure, diabetes mellitus, stroke, atrial fibrillation, mortality, coronary artery disease, cancer

ZFHX3 TCF7L2

1.09e-0420232EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004352, MONDO_0004992
Diseasetea consumption measurement

ZFHX3 FAM222A TCF7L2

1.36e-04129233EFO_0010091
Diseaseheart rate response to exercise

ACHE TCF7L2

5.15e-0443232EFO_0009184
Diseasetotal cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer

ZFHX3 TCF7L2

1.32e-0369232EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
Diseasealcohol use disorder measurement, alcohol consumption measurement

ZFHX3 TCF7L2

2.59e-0397232EFO_0007878, EFO_0009458
Diseasephysical activity measurement, body mass index

TCF7L2 TBX21

3.55e-03114232EFO_0004340, EFO_0008002
Diseaseprostate cancer (is_implicated_in)

ZFHX3 TCF7L2

3.73e-03117232DOID:10283 (is_implicated_in)
Diseasewaist circumference

CCDC34 FAM222A TCF7L2

4.35e-03429233EFO_0004342
Diseasebitter alcoholic beverage consumption measurement

ZFHX3 TCF7L2

4.79e-03133232EFO_0010092
Diseasemean arterial pressure

ZFHX3 NPR1 ZNF318

6.62e-03499233EFO_0006340

Protein segments in the cluster

PeptideGeneStartEntry
NEPRDPKAPQWPPYT

ACHE

521

P22303
SGLDYLLWPQKPPPP

FAM222A

281

Q5U5X8
LNWPLGYPPPDIPKC

NPR1

441

P16066
PKPYPRLPAWEKGEP

TSPOAP1

1546

O95153
GEWYQNFQPPPQPPS

CD6

626

P30203
VNWEPPQPLPFPKYL

LY6G5C

46

Q5SRR4
WQEGYPPPPLNTSPM

LATS1

296

O95835
WKLVPDNYPPGDQPP

MSL3

431

Q8N5Y2
AWVPGPPPYLPRQQS

ARHGAP33

961

O14559
ALPYPEKENRPPGWE

DRAXIN

116

Q8NBI3
PEPAFYNPIPWKPIH

CCDC34

311

Q96HJ3
HDQIPPNKPPWFDQP

CHERP

411

Q8IWX8
WFPLQLPKWPYPQAP

GLB1L

521

Q6UWU2
PKNPPPPINFQEWDG

DIMT1

211

Q9UNQ2
EWEYLPPVGPRPPKG

USP9X

1541

Q93008
LNSYPLKGPGLPPPW

TMEM200B

221

Q69YZ2
PLGWLVPQQGQPVYP

TCF7L2

256

Q9NQB0
APQMPPAGIYPPGLW

TEX13C

261

A0A0J9YWL9
ENDPYGPLPPGWEKR

WWP1

451

Q9H0M0
PPGYNGWQVLDPTPQ

TGM7

351

Q96PF1
PQGNLYQWGPLPGIP

ZNF318

446

Q5VUA4
YQWGPLPGIPKDNSP

ZNF318

451

Q5VUA4
LAPGAGWPVAPQYPP

TBX21

426

Q9UL17
GWPVAPQYPPKMGPA

TBX21

431

Q9UL17
SRPPSPEPPKQEYWG

ZFHX3

2226

Q15911
APEVQPYPKGWNLPG

NAALAD2

226

Q9Y3Q0