Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF355P ZNF208 ZNF770 ZNF213 ZNF81 ZNF467 SMYD3 ZNF674 ZNF92 ZNF491 ZFP62	1.31e-05	1459	33	11	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF355P ZNF208 ZNF770 ZNF213 ZNF81 ZNF467 ZNF674 ZNF92 ZNF491 ZFP62	6.22e-05	1412	33	10	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF355P ZNF208 ZNF770 ZNF213 ZNF81 ZNF467 SMYD3 ZNF92 ZFP62	1.35e-04	1244	33	9	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF355P ZNF208 ZNF770 ZNF213 ZNF81 ZNF467 SMYD3 ZNF92 ZFP62	1.59e-04	1271	33	9	GO:0000987
Domain	ZINC_FINGER_C2H2_2	ZNF208 ZNF770 ZNF213 ZNF81 ZNF467 CBLL2 ZNF674 ZNF92 ZNF491 ZFP62 ZNF541 FIZ1	1.63e-09	775	31	12	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF208 ZNF770 ZNF213 ZNF81 ZNF467 CBLL2 ZNF674 ZNF92 ZNF491 ZFP62 ZNF541 FIZ1	1.68e-09	777	31	12	PS00028
Domain	Znf_C2H2-like	ZNF208 ZNF770 ZNF213 ZNF81 ZNF467 CBLL2 ZNF674 ZNF92 ZNF491 ZFP62 ZNF541 FIZ1	2.21e-09	796	31	12	IPR015880
Domain	Znf_C2H2	ZNF208 ZNF770 ZNF213 ZNF81 ZNF467 CBLL2 ZNF674 ZNF92 ZNF491 ZFP62 ZNF541 FIZ1	2.51e-09	805	31	12	IPR007087
Domain	ZnF_C2H2	ZNF208 ZNF770 ZNF213 ZNF81 ZNF467 CBLL2 ZNF674 ZNF92 ZNF491 ZFP62 ZNF541 FIZ1	2.62e-09	808	31	12	SM00355
Domain	-	ZNF208 ZNF770 ZNF213 ZNF81 ZNF467 ZNF674 ZNF92 ZNF491 ZFP62 ZNF541 FIZ1	5.90e-09	679	31	11	3.30.160.60
Domain	zf-C2H2	ZNF208 ZNF770 ZNF213 ZNF81 ZNF467 ZNF674 ZNF92 ZNF491 ZFP62 ZNF541 FIZ1	7.29e-09	693	31	11	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF208 ZNF770 ZNF213 ZNF81 ZNF467 ZNF674 ZNF92 ZNF491 ZFP62 ZNF541 FIZ1	7.40e-09	694	31	11	IPR013087
Domain	zf-C2H2_6	ZNF208 ZNF770 ZNF467 ZNF92 ZFP62 ZNF541	1.11e-05	314	31	6	PF13912
Domain	KRAB	ZNF208 ZNF213 ZNF81 ZNF674 ZNF92	2.84e-04	358	31	5	PS50805
Domain	KRAB	ZNF208 ZNF213 ZNF81 ZNF674 ZNF92	2.84e-04	358	31	5	PF01352
Domain	KRAB	ZNF208 ZNF213 ZNF81 ZNF674 ZNF92	3.26e-04	369	31	5	SM00349
Domain	KRAB	ZNF208 ZNF213 ZNF81 ZNF674 ZNF92	3.30e-04	370	31	5	IPR001909
Domain	PLAC	ADAMTS12 PCSK6	4.48e-04	19	31	2	IPR010909
Domain	PLAC	ADAMTS12 PCSK6	4.48e-04	19	31	2	PS50900
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF355P ZNF208 ZFP62	1.39e-05	49	33	3	9630514
Pubmed	Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.	ZNF355P ZNF208	9.10e-05	15	33	2	15885501
Pubmed	Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.	ZNF208 ZNF92	1.04e-04	16	33	2	8467795
Pubmed	Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.	ZNF355P ZNF208	3.49e-04	29	33	2	14563677
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	BOD1L1 ANKRD12 VPS54 VEZT SMYD3 RNF144A RAI1	4.17e-04	1489	33	7	28611215
Pubmed	Cul3-KLHL20 Ubiquitin Ligase Governs the Turnover of ULK1 and VPS34 Complexes to Control Autophagy Termination.	VPS54 FIZ1	9.19e-04	47	33	2	26687681
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF208 ZNF770 ZNF213 ZNF81 ZNF467 ZNF674 ZNF92 ZNF491 ZFP62 ZNF541 FIZ1	1.61e-09	718	26	11	28
GeneFamily	X-linked mental retardation\|Angiotensin receptors	ZNF81 ZNF674	2.62e-03	53	26	2	103
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_500	CFH ANKRD12 CDKL2 ZFP62 PCSK6 ZNF541 WDR44	1.14e-06	387	31	7	gudmap_developingGonad_e18.5_ovary_500
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#5_top-relative-expression-ranked_1000	ANKRD12 CDKL2 ZFP62 ZNF541 WDR44	1.93e-05	230	31	5	gudmap_developingGonad_e18.5_ovary_1000_k5
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#1_top-relative-expression-ranked_500	CDKL2 ZFP62 ZNF541 WDR44	4.18e-05	134	31	4	gudmap_developingGonad_e18.5_ovary_500_k1
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000	CFH ANKRD12 CDKL2 ZFP62 PCSK6 ZNF541 WDR44	1.05e-04	778	31	7	gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#5_top-relative-expression-ranked_1000	ANKRD12 CDKL2 ZFP62 ZNF541	1.29e-04	179	31	4	gudmap_developingGonad_e14.5_ ovary_1000_k5
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#4_top-relative-expression-ranked_500	CFH ANKRD12 PCSK6	2.23e-04	81	31	3	gudmap_developingGonad_e18.5_ovary_500_k4
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#5_top-relative-expression-ranked_500	ANKRD12 CDKL2 WDR44	3.14e-04	91	31	3	gudmap_developingGonad_e14.5_ ovary_500_k5
Disease	nucleoside diphosphate kinase A measurement	CFH LTF	1.07e-06	2	31	2	EFO_0009947
Disease	myc target protein 1 measurement	CFH LTF	1.07e-06	2	31	2	EFO_0801812
Disease	leucine-rich repeats and immunoglobulin-like domains protein 3 measurement	CFH LRIG3	3.20e-06	3	31	2	EFO_0020534
Disease	neurexophilin-1 measurement	CFH PCSK6	2.98e-05	8	31	2	EFO_0008244
Disease	transmembrane protein 87B measurement	CFH PCSK6	8.27e-05	13	31	2	EFO_0802158
Disease	Mental Retardation, X-Linked	ZNF81 ZNF674	4.26e-04	29	31	2	C1136249

Protein segments in the cluster

Peptide	Gene	Start	Entry
EKPKCVEISCKSPDV	CFH	201	P08603
EQDPKHCPESEKCLL	ANKRD12	1666	Q6UB98
DLPIHFCDKCDLPIK	CBLL2	51	Q8N7E2
CAKNHDEPCDVTRKP	ADAMTS12	971	P58397
KGRKHECSKEAPAEP	RAI1	1801	Q7Z5J4
KKKECYPCSHPSEES	LRIG3	966	Q6UXM1
HPSCKKCVDEPEKCT	PCSK6	801	P29122
DADRKHCKFKPDPNI	EXOG	106	Q9Y2C4
EEDDAPIKRCPKCKV	RNF144A	176	P50876
VCAEKEEKHGKECPE	BOD1L1	2426	Q8NFC6
KCLHIDPDKRPFCAE	CDKL2	266	Q92772
AHTDVKPFKCPRCER	FIZ1	221	Q96SL8
PCHDKVSPEDFCEKM	OTOGL	1751	Q3ZCN5
CEKDPECKVDHKKGL	PWWP3A	166	Q2TAK8
EKLPTFHFCCEKPKV	SLFN14	276	P0C7P3
PDNTRKPVDKFKDCH	LTF	251	P02788
PDHKRECKCLKSCKP	SMYD3	81	Q9H7B4
KRIHTEEKPYKCEEC	ZNF92	276	Q03936
ELKKCFPSDETCEKP	WDR44	136	Q5JSH3
RHKICPCDKCEKVFP	ZNF770	471	Q6IQ21
EPCPKKCRICHMDEV	ZNFX1	1556	Q9P2E3
KRIHTDEKPYKCEEC	ZNF208	796	O43345
GEKPHKCPECDKSFR	ZNF213	341	O14771
SVHPGEKPFKCDECE	ZFP62	581	Q8NB50
PHTREKPFDCKECEK	ZNF491	96	Q8N8L2
KPFDCKECEKSFISP	ZNF491	101	Q8N8L2
KRIHTEEKPYKCEEC	ZNF355P	231	Q9NSJ1
KKGKPEIACENPHCT	VEZT	506	Q9HBM0
THTGEKPFVCDKCPK	ZNF674	301	Q2M3X9
CIKSKPKVDSDHCFP	TNFRSF17	131	Q02223
PFPCTECEKRFRKKT	ZNF467	271	Q7Z7K2
HTTEKPYKCPDCEKS	ZNF81	576	P51508
HERCKNICPPKDTFE	VPS54	131	Q9P1Q0
DDPCAPKKVKVDCDS	ZNF541	496	Q9H0D2