Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainDH_1

PLEKHG4B PLEKHG1 AKAP13 ARHGEF17

2.42e-0463904PS00741
DomainRhoGEF

PLEKHG4B PLEKHG1 AKAP13 ARHGEF17

3.24e-0468904SM00325
DomainRhoGEF

PLEKHG4B PLEKHG1 AKAP13 ARHGEF17

3.63e-0470904PF00621
DomainDH_2

PLEKHG4B PLEKHG1 AKAP13 ARHGEF17

3.63e-0470904PS50010
DomainDH-domain

PLEKHG4B PLEKHG1 AKAP13 ARHGEF17

3.83e-0471904IPR000219
Domain-

PLEKHG4B PLEKHG1 AKAP13 ARHGEF17

3.83e-04719041.20.900.10
DomainPDZ

MPP1 DLG2 SIPA1 SIPA1L2 AHNAK2

6.00e-04141905PF00595
DomainPDZ

MPP1 DLG2 SIPA1 SIPA1L2 AHNAK2

7.47e-04148905SM00228
Domain-

MPP1 DLG2 SIPA1 SIPA1L2 AHNAK2

7.94e-041509052.30.42.10
DomainPDZ

MPP1 DLG2 SIPA1 SIPA1L2 AHNAK2

8.18e-04151905PS50106
DomainPDZ

MPP1 DLG2 SIPA1 SIPA1L2 AHNAK2

8.43e-04152905IPR001478
DomainRap_GAP

SIPA1 SIPA1L2

1.01e-0310902PF02145
DomainRap_GAP_dom

SIPA1 SIPA1L2

1.23e-0311902IPR000331
DomainRAPGAP

SIPA1 SIPA1L2

1.23e-0311902PS50085
Domain-

PPFIA2 NAB2 EPHA1 ANKS1A

1.72e-031069041.10.150.50
DomainSAM/pointed

PPFIA2 NAB2 EPHA1 ANKS1A

2.47e-03117904IPR013761
DomainGuanylate_kinase_CS

MPP1 DLG2

2.64e-0316902IPR020590
Domain-

PLEKHG4B PLEKHG1 EVL MYO7A AKAP13 ARHGEF17 ANKS1A

2.81e-033919072.30.29.30
DomainZINC_FINGER_C2H2_2

KLF11 ZNF536 RBSN HIVEP2 KCMF1 ZNF76 KLF17 ZNF215 ZNF454 ZNF646

4.09e-037759010PS50157
DomainZINC_FINGER_C2H2_1

KLF11 ZNF536 RBSN HIVEP2 KCMF1 ZNF76 KLF17 ZNF215 ZNF454 ZNF646

4.16e-037779010PS00028
DomainSAM_1

PPFIA2 EPHA1 ANKS1A

4.33e-0368903PF00536
DomainPH_dom-like

PLEKHG4B PLEKHG1 EVL MYO7A AKAP13 ARHGEF17 ANKS1A

4.50e-03426907IPR011993
DomainCRAL_TRIO

PRUNE2 SEC14L1

4.54e-0321902PF00650
DomainZnf_C2H2-like

KLF11 ZNF536 RBSN HIVEP2 KCMF1 ZNF76 KLF17 ZNF215 ZNF454 ZNF646

4.92e-037969010IPR015880
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PITPNM2 PALD1 PLEKHG1 FLNA FOXK2 HIVEP2 PER2 MYO7A AKNA NSD1 AKAP13 PIGG ATG9A DOT1L HERC1 SIPA1L2 AHNAK2

3.81e-091105911735748872
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PLEKHG1 RBSN HIVEP2 SYDE2 APC AKAP13 USP54 SIPA1L2 SRRM2 ARHGEF17 AKAP1 LUZP1 AHNAK2 ANKS1A

5.35e-08861911436931259
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

HIVEP2 PER2 APC AKAP13 USP54 SIPA1L2 PRPF39 SON

1.83e-0723291825515538
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PRUNE2 ZNF536 PER2 SRRM2 ARHGEF17 ZNF646

3.35e-071049169205841
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

FLNA RBSN FOXK2 USP24 APC AKAP13 SRRM2 TERF2IP EPHA1 SON

8.26e-07503911016964243
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PALD1 PLEKHG1 ZNF536 PER2 SIPA1L2 SRRM2 ARHGEF17 NFAT5 SON

1.27e-0640791912693553
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

KLF11 HOXB5 ZNF536 RBSN FOXK2 HIVEP2 PER2 KLF17 PAX9 COPS6 NFAT5

2.52e-06709911122988430
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

BDP1 FLNA NSD1 APC CHD1 SRRM2 SON

4.41e-0625091733536335
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PITPNM2 EVL FLNA MYO7A PPFIA2 NCAN APC POR DLG2 USP54 NDUFA6 SIPA1 SIPA1L2 ARHGEF17 LUZP1

4.42e-061431911537142655
Pubmed

CD11b is required for the resolution of inflammation induced by Bordetella bronchiseptica respiratory infection.

C5 ITGAM

6.77e-06291216611225
Pubmed

Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death.

CASP3 C5

6.77e-06291217715065
Pubmed

Prostaglandin E receptor 4 (EP4) promotes colonic tumorigenesis.

APC PTGER4

6.77e-06291226378024
Pubmed

Inhibition and deficiency of the immunoproteasome subunit LMP7 suppress the development and progression of colorectal carcinoma in mice.

PSMB8 APC

6.77e-06291228881611
Pubmed

SON and SRRM2 are essential for nuclear speckle formation.

SRRM2 SON

6.77e-06291233095160
Pubmed

The COP9 signalosome-mediated deneddylation is stimulated by caspases during apoptosis.

CASP3 COPS6

6.77e-06291218060501
Pubmed

Period 2 mutation accelerates ApcMin/+ tumorigenesis.

PER2 APC

6.77e-06291219010825
Pubmed

Deafness due to degeneration of cochlear neurons in caspase-3-deficient mice.

MYO7A CASP3

6.77e-06291211374883
Pubmed

Granulocyte and monocyte CD11b expression during plasma separation is dependent on complement factor 5 (C5) - an ex vivo study with blood from a C5-deficient individual.

C5 ITGAM

6.77e-06291229575196
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NOL4 FLNA ZNF536 ZGRF1 USP24 APC AKAP1 LUZP1

1.45e-0541891834709266
Pubmed

Brx mediates the response of lymphocytes to osmotic stress through the activation of NFAT5.

AKAP13 NFAT5

2.03e-05391219211510
Pubmed

BNIP2 extra long inhibits RhoA and cellular transformation by Lbc RhoGEF via its BCH domain.

PRUNE2 AKAP13

2.03e-05391218445682
Pubmed

Combined effects of prostaglandin E receptor subtype EP1 and subtype EP4 antagonists on intestinal tumorigenesis in adenomatous polyposis coli gene knockout mice.

APC PTGER4

2.03e-05391212841871
Pubmed

Src homology 2 domain-containing phosphatase 2 (Shp2) is a component of the A-kinase-anchoring protein (AKAP)-Lbc complex and is inhibited by protein kinase A (PKA) under pathological hypertrophic conditions in the heart.

AKAP13 AKAP1

2.03e-05391223045525
Pubmed

AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development.

PRKAB2 CASP3 APC

2.23e-052191319217427
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

MPP1 PALD1 ZNF536 CASP3 APC AKAP13 CHD1 USP54 AKAP1 ANKS1A

2.25e-05733911034672954
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PLEKHG4B PRUNE2 PITPNM2 BDP1 EVL FOXK2 HIVEP2 MCM8 PPFIA2 AKAP13 ANKRD24 NFAT5 TERF2IP ANKS1A

3.19e-051489911428611215
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

FLNA ZGRF1 NSD1 HERC1 SRRM2 ARHGEF17

3.60e-0523491636243803
Pubmed

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.

MPP1 EVL PSMB8 AKAP13 ITGAM

3.83e-0514391530397336
Pubmed

The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination.

MYO7A CASP3

4.05e-05491211973280
Pubmed

Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis.

APC C5

4.05e-05491235649359
Pubmed

Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes.

GPR20 GPR22

4.05e-0549129073069
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

PITPNM2 EVL FLNA RBSN PPFIA2 USP24 APC PKP1 POR DLG2 NDUFA6 SIPA1L2

4.19e-051139911236417873
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

PRUNE2 MYO7A LRRC53 PSMB8 MROH7 CHD1 SIPA1L2 LUZP1

4.88e-0549691831343991
Pubmed

A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes.

AKAP13 NFAT5

6.74e-05591229298866
Pubmed

Beta-catenin induces beta-TrCP-mediated PER2 degradation altering circadian clock gene expression in intestinal mucosa of ApcMin/+ mice.

PER2 APC

6.74e-05591219106159
Pubmed

The fate of desmosomal proteins in apoptotic cells.

CASP3 PKP1

6.74e-05591211500511
Pubmed

Calcineurin in reactive astrocytes plays a key role in the interplay between proinflammatory and anti-inflammatory signals.

CASP3 ITGAM

6.74e-05591217699657
Pubmed

Developmental neuronal death in hippocampus requires the microglial CD11b integrin and DAP12 immunoreceptor.

CASP3 ITGAM

6.74e-05591218685038
Pubmed

Embryonic lethality in mice lacking the nuclear factor of activated T cells 5 protein due to impaired cardiac development and function.

CASP3 NFAT5

6.74e-05591221765887
Pubmed

FilaminA and Formin2 regulate skeletal, muscular, and intestinal formation through mesenchymal progenitor proliferation.

FLNA CASP3

6.74e-05591229240780
Pubmed

Methionine sulfoxide reductase B3 deficiency causes hearing loss due to stereocilia degeneration and apoptotic cell death in cochlear hair cells.

MYO7A CASP3

6.74e-05591224191262
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

PITPNM2 PPFIA2 NCAN PKP1 DLG2 LUZP1

9.89e-0528191628706196
Pubmed

Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice.

APC PTGER4

1.01e-04691211533709
Pubmed

Clearance of Bordetella parapertussis from the lower respiratory tract requires humoral and cellular immunity.

C5 ITGAM

1.01e-04691216177324
Pubmed

ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway.

CASP3 ATG9A

1.01e-04691236520901
Pubmed

Complement inhibition and statins prevent fetal brain cortical abnormalities in a mouse model of preterm birth.

CASP3 C5

1.01e-04691224184716
Pubmed

POU4F3 pioneer activity enables ATOH1 to drive diverse mechanoreceptor differentiation through a feed-forward epigenetic mechanism.

MYO7A CASP3

1.01e-04691234266958
Pubmed

Fungal dissemination is limited by liver macrophage filtration of the blood.

C5 ITGAM

1.01e-04691231594939
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

MPP1 EVL FLNA PPFIA2 DLG2 ANKRD24 SIPA1 COPS6

1.13e-0456091821653829
Pubmed

The Phox (PX) domain proteins and membrane traffic.

SNX20 KIF16B

1.41e-04791216782399
Pubmed

The role of sensory organs and the forebrain for the development of the craniofacial shape as revealed by Foxg1-cre-mediated microRNA loss.

MYO7A CASP3

1.41e-04791221225654
Pubmed

Modeling of a human circadian mutation yields insights into clock regulation by PER2.

PER2 APC

1.41e-04791217218255
Pubmed

Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal.

MYO7A CASP3

1.41e-04791232482884
Pubmed

The complex mechanism of antibody-mediated clearance of Bordetella from the lungs requires TLR4.

C5 ITGAM

1.41e-04791216301658
Pubmed

Cross-regulation of Ngn1 and Math1 coordinates the production of neurons and sensory hair cells during inner ear development.

MYO7A CASP3

1.41e-04791218039969
Pubmed

Neurod1 regulates survival and formation of connections in mouse ear and brain.

MYO7A CASP3

1.41e-04791220512592
Pubmed

A targeted association study in systemic lupus erythematosus identifies multiple susceptibility alleles.

C5 ITGAM PTGER4

1.48e-043991320962850
Pubmed

Biological insights from 108 schizophrenia-associated genetic loci.

PITPNM2 ZNF536 NCAN NAB2 PPP1R16B NDUFA6

1.49e-0430391625056061
Pubmed

Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.

APC SRRM2 ARHGEF17 ANKS1A

1.53e-0410291415778465
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

NOL4 ZNF536 MCM8 USP54 SIPA1 SIPA1L2 SRRM2 UNC80 LUZP1 SON ZNF646

1.60e-041116911131753913
Pubmed

C3 opsonization regulates endocytic handling of apoptotic cells resulting in enhanced T-cell responses to cargo-derived antigens.

C5 ITGAM

1.88e-04891224474777
Pubmed

Neural crest-specific deletion of Ldb1 leads to cleft secondary palate with impaired palatal shelf elevation.

CASP3 PAX9

1.88e-04891224433583
Pubmed

Rack1 regulates cellular patterning and polarity in the mouse cochlea.

MYO7A FZD3

1.88e-04891236252648
Pubmed

CHD7 and SOX2 act in a common gene regulatory network during mammalian semicircular canal and cochlear development.

MYO7A CASP3

1.88e-04891238408234
Pubmed

In vivo genetic ablation of the periotic mesoderm affects cell proliferation survival and differentiation in the cochlea.

MYO7A CASP3

1.88e-04891217825816
Pubmed

The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis.

CASP3 COPS6

1.88e-04891217337451
Pubmed

The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival.

MYO7A CASP3

1.88e-04891212441305
Pubmed

Frizzled3 is required for neurogenesis and target innervation during sympathetic nervous system development.

FZD3 CASP3

1.88e-04891221325504
Pubmed

Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.

CASP3 APC

1.88e-04891229170395
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

EVL FLNA ARID4A USP24 SRRM2 AKAP1 TERF2IP SON ANKS1A

1.97e-0477491915302935
Pubmed

Kit ligand has a critical role in mouse yolk sac and aorta-gonad-mesonephros hematopoiesis.

CASP3 ITGAM

2.41e-04991230166337
Pubmed

Function of bidirectional sensitivity in the otolith organs established by transcription factor Emx2.

MYO7A CASP3

2.41e-04991236280667
Pubmed

Casz1 is required for cardiomyocyte G1-to-S phase progression during mammalian cardiac development.

FLNA CASP3

2.41e-04991225953344
Pubmed

Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription.

CASP3 CHD1

2.41e-04991225831528
Pubmed

Identification of quantitative trait loci controlling cortical motor evoked potentials in experimental autoimmune encephalomyelitis: correlation with incidence, onset and severity of disease.

CASP3 C5

2.41e-04991215917267
Pubmed

Involvement of prostaglandin E receptor subtype EP(4) in colon carcinogenesis.

APC PTGER4

2.41e-04991211782353
Pubmed

Urothelial Defects from Targeted Inactivation of Exocyst Sec10 in Mice Cause Ureteropelvic Junction Obstructions.

CASP3 UPK3A

2.41e-04991226046524
Pubmed

Interaction of TAGLN and USP1 promotes ZEB1 ubiquitination degradation in UV-induced skin photoaging.

USP24 USP54

2.41e-04991237149635
Pubmed

Msx1 haploinsufficiency modifies the Pax9-deficient cardiovascular phenotype.

CASP3 PAX9

2.41e-04991234615475
Pubmed

A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth.

MYO7A FZD3

2.41e-04991218339676
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

EVL RBSN PPFIA2 SIPA1L2 LUZP1

2.77e-0421891533378226
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

MPP1 FLNA USP24 ITGAM SRRM2 SON

2.95e-0434491630333137
Pubmed

Celsr3 is required in motor neurons to steer their axons in the hindlimb.

FZD3 CASP3

3.01e-041091225108913
Pubmed

Conditional deletion of Atoh1 reveals distinct critical periods for survival and function of hair cells in the organ of Corti.

MYO7A CASP3

3.01e-041091223761906
Pubmed

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS.

CASP3 APC

3.01e-041091219515974
Pubmed

Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling.

CASP3 ITGAM

3.01e-041091232341550
Pubmed

Microglia proliferation is controlled by P2X7 receptors in a Pannexin-1-independent manner during early embryonic spinal cord invasion.

CASP3 ITGAM

3.01e-041091222915101
Pubmed

Interaction network of human early embryonic transcription factors.

NOL4 ZNF536 FOXK2 HIVEP2 ARID4A NAB2

3.28e-0435191638297188
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

PALD1 ANOS1 ZGRF1 NCAN USP24 NSD1 CHD1 ANKRD24 USP54 SIPA1L2 EPHA1

3.32e-041215911115146197
Pubmed

FGF11 induced by hypoxia interacts with HIF-1α and enhances its stability.

FNDC3B HERC1 SRRM2 SON

3.65e-0412891428027390
Pubmed

Embryonic macrophages and microglia ablation alter the development of dorsal root ganglion sensory neurons in mouse embryos.

CASP3 ITGAM

3.67e-041191230252950
Pubmed

Metabolic-stress-induced rearrangement of the 14-3-3ζ interactome promotes autophagy via a ULK1- and AMPK-regulated 14-3-3ζ interaction with phosphorylated Atg9.

AKAP13 ATG9A

3.67e-041191225266655
Pubmed

Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.

PLEKHG1 RBSN

3.67e-041191222488850
Pubmed

An Atoh1-S193A Phospho-Mutant Allele Causes Hearing Deficits and Motor Impairment.

MYO7A CASP3

3.67e-041191228729444
Pubmed

Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase.

CASP3 APC

3.67e-041191220648636
Pubmed

Developmental basis for filamin-A-associated myxomatous mitral valve disease.

FLNA CASP3

3.67e-041191222843703
Pubmed

The adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex.

CASP3 APC

3.67e-041191219146812
Pubmed

Rab11a Is Essential for the Development and Integrity of the Stereocilia and Kinocilia in the Mammalian Organ of Corti.

MYO7A FZD3

3.67e-041191237225424
Pubmed

Defects in the Alternative Splicing-Dependent Regulation of REST Cause Deafness.

MYO7A CASP3

3.67e-041191229961578
Pubmed

Pax9 is required for cardiovascular development and interacts with Tbx1 in the pharyngeal endoderm to control 4th pharyngeal arch artery morphogenesis.

CASP3 PAX9

3.67e-041191231444215
InteractionYWHAH interactions

PLEKHG1 RBSN HIVEP2 SYDE2 APC AKAP13 ATG9A USP54 HERC1 SIPA1 SIPA1L2 SRRM2 ARHGEF17 AKAP1 LUZP1 AHNAK2 ANKS1A

5.59e-0611028917int:YWHAH
InteractionYWHAG interactions

PLEKHG1 FLNA HIVEP2 SYDE2 USP24 CASP3 APC AKAP13 ATG9A USP54 SIPA1 SIPA1L2 SRRM2 ARHGEF17 LUZP1 SON AHNAK2 ANKS1A

7.19e-0612488918int:YWHAG
InteractionFBXW11 interactions

FLNA HIVEP2 PER2 CASP3 APC AKAP13 CHD1 USP54 SIPA1L2 PRPF39 SON

7.45e-064738911int:FBXW11
InteractionRCOR1 interactions

NOL4 FLNA ZNF536 FOXK2 ARID4A ZGRF1 USP24 APC AKAP1 TERF2IP LUZP1

1.12e-054948911int:RCOR1
InteractionTOP3B interactions

PITPNM2 PALD1 PLEKHG1 FLNA ANOS1 FOXK2 HIVEP2 PER2 MYO7A KCMF1 AKNA NSD1 AKAP13 PIGG ATG9A DOT1L HERC1 SIPA1L2 AHNAK2

1.82e-0514708919int:TOP3B
InteractionGSN interactions

PLEKHG1 FLNA PER2 SYDE2 CASP3 DOT1L ARHGEF17

4.29e-05212897int:GSN
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

MYO7A AKAP13 AKAP1

2.05e-0429723396
GeneFamilyPDZ domain containing

MPP1 DLG2 SIPA1 SIPA1L2 AHNAK2

3.50e-041527251220
GeneFamilyZinc fingers C2H2-type|Kruppel like factors

KLF11 KLF17

2.30e-0318722624
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG1 AKAP13 ARHGEF17

2.32e-0366723722
GeneFamilyCD molecules|Mucins

MUC16 MUC22

3.13e-0321722648
GeneFamilyFibronectin type III domain containing

FNDC3B ANOS1 CNTN3 EPHA1

3.81e-03160724555
GeneFamilyCalcium voltage-gated channel subunits|Membrane associated guanylate kinases

MPP1 DLG2

4.78e-0326722904
GeneFamilySterile alpha motif domain containing

PPFIA2 EPHA1 ANKS1A

5.22e-0388723760
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R16B APC DLG2 AKAP1

5.89e-03181724694
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

KLF11 ZNF536 HIVEP2 ZNF76 KLF17 ZNF215 ZNF454 ZNF646

7.58e-0371872828
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

NSD1 DOT1L

8.08e-0334722487
GeneFamilyComplement system|Sushi domain containing

C5 ITGAM

9.03e-0336722492
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

BDP1 EVL FLNA HIVEP2 ARID4A MYO7A KCMF1 USP24 PSMB8 PPP1R16B AKNA NSD1 AKAP13 CHD1 HERC1 SIPA1 NFAT5 PTGER4 TERF2IP LUZP1 SON

1.60e-0814928821M40023
CoexpressionGSE13522_WT_VS_IFNG_KO_SKIN_UP

NOL4 FZD3 CLEC1A CNTN3 KLF17 UNC80 EPHA1

4.28e-07138887M2913
CoexpressionGSE25123_CTRL_VS_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DN

FLNA ZNF536 ARID4A SNX20 PRKAB2 C5 HERC1

4.94e-06199887M7998
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_ACTC_POS_SMC_CELL

PLEKHG4B PRUNE2 ANOS1 FZD3 KCMF1 PRKAB2 SIPA1L2 AKAP1 AHNAK2 ANKS1A

2.85e-055898810M45662
CoexpressionGSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_UP

KLF11 RBSN FOXK2 USP24 ATG9A ANKS1A

4.44e-05190886M3289
CoexpressionIVANOVA_HEMATOPOIESIS_STEM_CELL_SHORT_TERM

KIF16B APC PKP1

5.38e-0522883M14523
CoexpressionIVANOVA_HEMATOPOIESIS_STEM_CELL_SHORT_TERM

KIF16B APC PKP1

5.38e-0522883MM676
CoexpressionGSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_DN

PER2 MYO7A POR ITGAM SEC14L1 ANKS1A

5.90e-05200886M5204
CoexpressionGSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_DN

EVL HIVEP2 SNX20 ZNF76 AKAP13 C5

5.90e-05200886M8618
CoexpressionRODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN

RBSN HIVEP2 FZD3 NSD1 POR USP54 HERC1 SRRM2 AKAP1 PTGER4 ANKS1A

8.15e-058078811M16651
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PITPNM2 PALD1 PLEKHG1 CLEC1A SIPA1L2 LUZP1 SEC14L1

8.90e-08180917d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MPP1 PITPNM2 PLEKHG1 PSMB8 PPP1R16B CLEC1A SIPA1

1.20e-07188917b294d6658e79328bd6fa33223e8c70117ba9789b
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PITPNM2 PALD1 PLEKHG1 CLEC1A SIPA1L2 LUZP1 SEC14L1

1.33e-071919171de0bdfd13bd930691564c2673f2e66393bc0255
ToppCellSigmoid-Macrophage-Macrophage|Macrophage / Region, Cell class and subclass

PALD1 FNDC3B EVL AKNA PTGER4 SEC14L1

1.27e-06168916bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PITPNM2 PALD1 PLEKHG1 PPP1R16B SIPA1L2 SEC14L1

2.67e-061919162f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature2_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MPP1 PITPNM2 PSMB8 PPP1R16B CLEC1A SIPA1

2.75e-06192916f68e6cbde87678122da1b5c0061904cfb7d04bf5
ToppCellEndothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|World / Lineage, Cell type, age group and donor

PITPNM2 PALD1 PLEKHG1 CLEC1A SIPA1L2 SEC14L1

2.75e-061929161e156bab5ecf64627890d2de9b27603d9a01f28d
ToppCellFetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PITPNM2 PLEKHG1 PPP1R16B CLEC1A SIPA1L2 SEC14L1

2.84e-06193916ad2df9b77999780860141be6ec366afc0172a331
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BDP1 PER2 NSD1 CHD1 LUZP1 SON

2.92e-06194916e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

PALD1 PLEKHG1 PPP1R16B CLEC1A SIPA1L2 SEC14L1

3.01e-06195916a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellCOVID-19-lung-Capillary_Aerocytes|COVID-19 / Disease (COVID-19 only), tissue and cell type

PITPNM2 PALD1 PLEKHG1 CLEC1A SIPA1L2 SEC14L1

3.10e-0619691649cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SIPA1L2 SEC14L1

3.10e-06196916ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

PALD1 PLEKHG1 PPP1R16B CLEC1A SIPA1L2 SEC14L1

3.10e-06196916b71b197cb92117dd9efaa13de000841901cc4ca8
ToppCellCOVID-19-lung-Capillary_Aerocytes|lung / Disease (COVID-19 only), tissue and cell type

PITPNM2 PALD1 PLEKHG1 CLEC1A SIPA1L2 SEC14L1

3.10e-061969164ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANOS1 PKP1 MUC16 CNTN3 PAX9 SIPA1L2

3.19e-06197916107cb153ea7fc74bbd244dbb9d0499c0a8506724
ToppCellBronchial_Biopsy|World / Tissue, Lineage and Cell class of Lung Cells from 10X

ANOS1 PER2 PKP1 PAX9 NFAT5 AHNAK2

3.29e-06198916f5b7013045b61fc56894f80092f799770dde1c8f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MPP1 PALD1 NAB2 AKAP13 DOT1L LUZP1

3.39e-06199916b0a906586e58009f5ed9272fc29ba28e49c85ee6
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon-Neuronal|3_mon / Sample Type, Dataset, Time_group, and Cell type.

NOL4 HIVEP2 GPR22 PPFIA2 DLG2 TERF2IP

3.39e-061999161029f3458b7fda464aa0e7ef06e081e2618c1388
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon-Neuronal-PNs|3_mon / Sample Type, Dataset, Time_group, and Cell type.

NOL4 HIVEP2 GPR22 PPFIA2 DLG2 TERF2IP

3.39e-061999168a04398653a1794921d73a6a950c1fb6fdf68c85
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

PRUNE2 SYDE2 PRKAB2 PSMB8 PIGG ANKS1A

3.48e-062009166b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCellControl-Endothelial_cells-Inflamed_endothelial_cells|Control / group, cell type (main and fine annotations)

PALD1 PLEKHG1 CLEC1A SIPA1L2 SEC14L1

1.94e-05160915958256e3d3836160763b82bb48f794087918d935
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PER2 MCM8 ZGRF1 ATG9A USP54

2.60e-05170915b1a16600754e0c12f7d39c9221f1b03135833f16
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PKP1 SEC14L1 ANKS1A

2.82e-05173915f193c63cc536d891c9d23043765e320252bb6e65
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PKP1 MUC16 USP54 PAX9 AHNAK2

3.07e-051769158d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA PPP1R16B AKNA ITGAM UNC80

3.07e-051769156b06da40eb97ea2db09f3a769494738b3e5fe3fa
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSMB8 NSD1 CHD1 SRRM2 LUZP1

3.24e-0517891501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

3.32e-051799158f9e538c822940785130297712b75131812a4603
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PRUNE2 PITPNM2 HIVEP2 PPP1R16B DLG2

3.32e-0517991514fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellCOVID-19-kidney-PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PITPNM2 PLEKHG1 PPP1R16B SIPA1L2 SEC14L1

3.41e-05180915493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

PALD1 PLEKHG1 CLEC1A SIPA1L2 SEC14L1

3.41e-05180915b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

PITPNM2 PALD1 PLEKHG1 CLEC1A SEC14L1

3.50e-05181915c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PITPNM2 PALD1 PLEKHG1 CLEC1A SEC14L1

3.60e-05182915a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCellAdult-Epithelial-basal_cell|Adult / Lineage, Cell type, age group and donor

ANOS1 PKP1 CNTN3 PAX9 C2orf78

3.69e-0518391500a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SIPA1L2

3.79e-05184915688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 HIVEP2 CLEC1A SIPA1L2 LUZP1

3.79e-05184915c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCellP28-Endothelial|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PSMB8 PPP1R16B CLEC1A SIPA1 LUZP1

3.79e-05184915b056411f499866097f4322999cfd1e57a3927b78
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA GPR20 MYO7A DOT1L ARHGEF17

3.89e-0518591538486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PITPNM2 PLEKHG1 CLEC1A SIPA1L2 SEC14L1

3.89e-05185915673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA GPR20 MYO7A DOT1L ARHGEF17

3.89e-051859153c28b5ceba3cfdb6f7e32d5b42e03b6a81a7a658
ToppCellP28-Endothelial-capillary_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PSMB8 PPP1R16B CLEC1A SIPA1 LUZP1

3.99e-0518691526a625ca0300055d6af3472aa0bfba59b73db292
ToppCellPCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating2_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MPP1 PITPNM2 PPP1R16B CLEC1A SIPA1

3.99e-051869152cbf1aaff87cd9fba01f814a119fe86e5af82290
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

ARID4A KIF16B APC NFAT5 LUZP1

3.99e-0518691503db813598b67b1e08f759758a1c2023396921fa
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 PLEKHG1 CLEC1A SIPA1L2 LUZP1

4.09e-05187915ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellControl-Endothelial_cells-Endothelial_cells_(general)|Control / group, cell type (main and fine annotations)

PALD1 PLEKHG1 CLEC1A SEC14L1 ANKS1A

4.09e-05187915fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD1 NDUFA6 SRRM2 LUZP1 SON

4.20e-05188915d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 PITPNM2 ZNF536 GPR20 AKAP1

4.20e-05188915f54b063025d80de631382bf5326bc40aab7f7d00
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 FLNA ZNF536 ANOS1 AHNAK2

4.31e-05189915da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCellASK452-Immune-T_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

PPFIA2 MUC16 HERC1 PTGER4 TERF2IP

4.31e-05189915f5dc500f77f04a110dd4a65cf4c03068a495dbdb
ToppCellControl-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 PLEKHG1 CLEC1A SIPA1L2 SEC14L1

4.31e-051899155d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NOL4 HOXB5 PPFIA2 LRRC53 UNC80

4.41e-0519091540d8b3403f4e38436b961cd3a2e69826cbae3042
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NOL4 HOXB5 PPFIA2 LRRC53 UNC80

4.41e-05190915f6cbf6d292f488ada5f7581e1dceba6198b933d1
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(general)|COVID-19 / group, cell type (main and fine annotations)

PITPNM2 PLEKHG1 CLEC1A PKP1 SEC14L1

4.41e-05190915812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLEKHG4B PRUNE2 FLNA SYDE2 AHNAK2

4.41e-05190915e102622f05c7f3e1bd8b224ea159d57033793ee0
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NOL4 HOXB5 PPFIA2 LRRC53 UNC80

4.41e-05190915a9a705455019e28d655636de73b07540798f82e6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

4.53e-05191915f663131a4810584c5854bd64ee7991a237b7707f
ToppCellPCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MPP1 PLEKHG1 PSMB8 PPP1R16B CLEC1A

4.53e-05191915edfd5eeff69b5de19c5df3d899e42acd7e015913
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRUNE2 FLNA ANOS1 SYDE2 AHNAK2

4.53e-05191915de2cd94ee88a7754f86d39469e38374d668210c7
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

PITPNM2 PALD1 PLEKHG1 CLEC1A SEC14L1

4.53e-05191915f229abf69a1217194f74b0502486907e07dba989
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 PLEKHG1 PPP1R16B CLEC1A SIPA1L2

4.64e-0519291504f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellPCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating2_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MPP1 PITPNM2 PSMB8 PPP1R16B CLEC1A

4.64e-05192915ac3d87aa301d30515c369bd7fc16f33b82173a85
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 PLEKHG1 PPP1R16B CLEC1A SIPA1L2

4.64e-05192915c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

4.64e-05192915c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PITPNM2 PALD1 PLEKHG1 CLEC1A SEC14L1

4.76e-05193915f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 PLEKHG1 PPP1R16B CLEC1A SIPA1L2

4.76e-05193915e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature1_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MPP1 PITPNM2 PSMB8 PPP1R16B CLEC1A

4.76e-051939152661ad9107ed9231e4afea4442a79051139a31df
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 PLEKHG1 CLEC1A SIPA1L2 SEC14L1

4.76e-05193915aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 PLEKHG1 CLEC1A SIPA1L2 SEC14L1

4.76e-05193915c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)|Adult / Lineage, Cell type, age group and donor

PITPNM2 PALD1 PLEKHG1 CLEC1A PKP1

4.76e-0519391539c6c96a2a100b1b290a779d36cc6bc17245720b
ToppCellPCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating3_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MPP1 PITPNM2 PSMB8 PPP1R16B CLEC1A

4.76e-05193915f7e4a390921780587b9bd084e495e646fa1ec74f
ToppCellPCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating3_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 PSMB8 PPP1R16B CLEC1A SIPA1

4.76e-0519391572128ece598070f8e752a0691e024e26ab364989
ToppCellCOVID-19-Endothelial_cells-Inflamed_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

PITPNM2 PLEKHG1 CLEC1A PKP1 SEC14L1

4.76e-05193915979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 PLEKHG1 CLEC1A SIPA1L2 LUZP1

4.76e-05193915a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

4.76e-0519391552e918884877b6659cdca0496390e440f73694a9
ToppCell10x3'2.3-week_14-16-Lymphocytic_B-B_lineage-pro_B_progenitor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MPP1 PLEKHG4B EVL PSMB8 TERF2IP

4.87e-05194915f64da5f62e29253d60b9546edf734ba5c17daae1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

4.87e-05194915f76808666fb875fc787751cbfd924d9be20a8192
ToppCellPCW_05-06-Endothelial|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MPP1 PITPNM2 PSMB8 PPP1R16B CLEC1A

4.87e-0519491500291c62795a55a7e63b1db10c139d6a3298e55e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

4.87e-0519491574a9fdb73f279bebb6337510deab9aaaf9f7e957
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 PLEKHG1 PPP1R16B CLEC1A SIPA1L2

4.87e-051949150b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellPCW_05-06-Endothelial-Endothelial_immature|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MPP1 PITPNM2 PSMB8 PPP1R16B CLEC1A

4.87e-051949159bd25ea57f2da27bd200d1a8bf797fec77d172c7
ToppCellPCW_05-06-Endothelial-Endothelial_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MPP1 PITPNM2 PSMB8 PPP1R16B CLEC1A

4.87e-05194915eb279e0d922de921343f0ae032a809f837d915b3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

4.87e-05194915f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

4.87e-05194915a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|Liver / Manually curated celltypes from each tissue

PER2 PPP1R16B AKNA SRRM2 PTGER4

4.99e-05195915972b09697b7b66fb8a27dfc0c0b05a844121f055
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo|Liver / Manually curated celltypes from each tissue

PER2 PPP1R16B AKNA SRRM2 PTGER4

4.99e-05195915c29c4ae95a756e3ced0f0747bbfe343590e5b8ab
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD1 HERC1 SRRM2 UNC80 SON

4.99e-051959153e519cffa6144a62b06124642a14c9ff39b76554
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

PITPNM2 PLEKHG1 PPP1R16B CLEC1A SEC14L1

4.99e-0519591550a193475db1bb1e05b8590225a553688c372c14
ToppCellPCW_07-8.5-Endothelial-Endothelial_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MPP1 PITPNM2 PSMB8 PPP1R16B CLEC1A

4.99e-05195915804b7c44aaaf8ba77e36f377955df261e92f5ff9
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

PLEKHG1 PPP1R16B HERC1 SEC14L1 ANKS1A

5.12e-05196915e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

5.12e-0519691522767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BDP1 EVL USP24 PPP1R16B PRPF39

5.12e-051969150175b097ad1338a07afebe3b5c7fd0bb0bb950f7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

5.12e-05196915b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCellFetal_29-31_weeks-Endothelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

5.12e-051969153981f6c7487598f4f7ce4650ac0ac5bd41481d66
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

5.12e-05196915145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

5.12e-05196915adee900dcd16dbaba15c58bdcace09ba20214950
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

5.12e-05196915e224338490691d92c1f70b57112fabdcc92b06a9
ToppCellEndothelial|World / Lineage, Cell type, age group and donor

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

5.12e-0519691596c6d78482a130ce4e29f6629972a06d10d7530e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

5.12e-05196915d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 PLEKHG1 PPP1R16B CLEC1A SEC14L1

5.24e-05197915c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRUNE2 FLNA ZNF536 GPR20 PPFIA2

5.24e-05197915bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-MYL4+_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 FLNA ANOS1 GPR20 AHNAK2

5.24e-051979154797f414330316e2ac2cf7cd2570d991877d7a38
Diseaseneutropenia (implicated_via_orthology)

C5 ITGAM

1.83e-047882DOID:1227 (implicated_via_orthology)
Diseasepuberty onset measurement

FNDC3B ZNF536 AKAP1 NFAT5

5.44e-04125884EFO_0005677
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

PITPNM2 USP24 SIPA1 ITGAM NFAT5

5.44e-04222885EFO_0008317, EFO_0020943
Diseasesystemic lupus erythematosus, COVID-19

PSMB8 CLEC1A ITGAM

7.02e-0458883MONDO_0007915, MONDO_0100096
Diseaseattention deficit hyperactivity disorder, schizophrenia

ZNF536 NAB2 PPP1R16B

9.36e-0464883EFO_0003888, MONDO_0005090
DiseaseTourette syndrome, schizophrenia

PITPNM2 ZNF536

1.30e-0318882EFO_0004895, MONDO_0005090
Diseasecardiovascular disease

PLEKHG1 HOXB5 HIVEP2 DLG2 SIPA1L2 NFAT5

2.48e-03457886EFO_0000319
Diseasepallidum volume

DLG2 HAL

2.52e-0325882EFO_0006933
Diseaselevel of Sterol ester (27:1/16:0) in blood serum

NCAN USP24

2.73e-0326882OBA_2045191
Diseasesystemic scleroderma, systemic lupus erythematosus

ITGAM ANKS1A

2.73e-0326882EFO_0000717, MONDO_0007915
Diseasecoronary artery disease

PLEKHG1 FNDC3B HIVEP2 ARID4A AKAP13 C5 SIPA1 MUC22 NFAT5 ANKS1A

2.93e-0311948810EFO_0001645
Diseaseeye measurement

AKAP13 HERC1

2.94e-0327882EFO_0004731

Protein segments in the cluster

PeptideGeneStartEntry
TSVSISMGHAESLSG

EPHA1

436

P21709
TSTSRQTDTHLMQSG

BDP1

1326

A6H8Y1
EADHSGGSDRNSMDS

AKAP1

566

Q92667
DREVSHAGASMSSAS

ARID4A

1221

P29374
DHVARMTATGSGENS

COPS6

201

Q7L5N1
MTATGSGENSTVAEH

COPS6

206

Q7L5N1
HSSTTMLSGVTGQSH

C2orf78

101

A6NCI8
IATGSSMRSDGTDNA

ADAM18

581

Q9Y3Q7
SSGDVVSMHRSSKGS

GPR20

321

Q99678
GLSTSSTAAELQHGM

AKAP13

846

Q12802
MGNTTSDRVSGERHG

PRKAB2

1

O43741
HSLDSMASGRSSDQD

ANKS1A

371

Q92625
SSAATRLTNSHAMGS

DOT1L

1511

Q8TEK3
GSRATGMESTGVSAT

ANKRD24

676

Q8TF21
HKSTGMTSRSGTDVD

CASP3

56

P42574
MNGHSDEESVRNSSG

CHD1

1

O14646
TAATGMNDVSSRSHA

KIF16B

211

Q96L93
SSKETMNVASSGHSR

MROH7

271

Q68CQ1
MNVASSGHSRSDLSV

MROH7

276

Q68CQ1
AMGSEQDSTPESRHG

NSD1

206

Q96L73
NSVHGSRRGSISSMS

RBSN

221

Q9H1K0
VDEHGTRLSGNMFST

PSMB8

186

P28062
LQGSGTMDSRHSVSI

PALD1

21

Q9ULE6
ATSAMDEGLTSGHSD

ARHGEF17

771

Q96PE2
STMGDRGTSNHSEMT

OR9K2

21

Q8NGE7
RTTGSEASSGMTHEN

ANOS1

471

P23352
SMAVTNVGTTSSGHE

MUC16

10101

Q8WXI7
MQAAREGSHSVTASA

PAX9

326

P55771
MGDSHVDTSSTVSEA

POR

1

P16435
FERSQHGSGMSNRST

MCM8

761

Q9UJA3
STMGASSTTSAHGVR

MUC22

1601

E2RYF6
SETAGTRKGSMSNGH

NAB2

131

Q15742
SQGSVDVSMGHSSFI

FOXK2

61

Q01167
ATDQGTTESTEHMGQ

LRRC53

896

A6NM62
STSASEGGGLMTRSE

HERC1

1476

Q15751
DVDMSSGSSGHETNE

PER2

31

O15055
SQRTSSAMSGHSRSF

PTGER4

366

P35408
QGSSHDESSMSGLAA

EVL

211

Q9UI08
MAGSGVRQATSTAST

NDUFA6

1

P56556
CSRHSSSSTMLDGTG

PITPNM2

696

Q9BZ72
RETSVASMSQTSGGE

NFAT5

41

O94916
HTEDTTSSSTQMIDG

PRPF39

621

Q86UA1
GMDLSVNRSSASSSH

HOXB5

51

P09067
HLGSSMARTGESSSE

PPP1R16B

501

Q96T49
MGTSSTDSQQAGHRR

CEMP1

1

Q6PRD7
SLSTSAATEDHVSMG

HAL

521

P42357
MSSSHSRAGQSAAGA

FLNA

1

P21333
DLGDTSITVGNTTMH

FNDC3B

906

Q53EP0
TMTGSGVDARTASSG

ATG9A

671

Q7Z3C6
SREESSSGSSHAVMD

C5

1411

P01031
ASHQSSMTSLEGSGI

AKNA

881

Q7Z591
AAKASHMGVSTDSGT

LUZP1

431

Q86V48
HGTSMNRVIEEDGTS

FZD3

651

Q9NPG1
SDSGDVTTTVHMDAA

KLF11

76

O14901
ARRSNMHFTSSSTGG

KCMF1

166

Q9P0J7
LNMSSSSGSSGVHTS

KLF17

36

Q5JT82
NHSMSSGSGSLRTNQ

DLG2

521

Q15700
SEGESGGSMHTALSD

MPP1

6

Q00013
HEATDMSQSSGGRNV

GPR22

266

Q99680
RGSMTSLESSHSGFS

SEC14L1

681

Q92503
SMDARGSTSAISNVH

CNTN3

996

Q9P232
ASSEGSTESEHLEGM

PPFIA2

231

O75334
SSQSSTLSHSNRGSM

PKP1

56

Q13835
SEHAGDIQTTRSNGM

SYDE2

426

Q5VT97
ATTTSSAGDHNGMLS

SRRM2

2481

Q9UQ35
SQRNSGETTETSDGM

PRUNE2

1436

Q8WUY3
SDMGAGTAASSHTEV

NCAN

456

O14594
GSMGDLSEISSHSSG

SIPA1L2

1331

Q9P2F8
RSQGMGSHSEASSGT

SIPA1

131

Q96FS4
EGTQTGSSSSFEHEM

ITGAM

336

P11215
IASGGTHSREMGDSN

NOL4

276

O94818
THSREMGDSNSDGKT

NOL4

281

O94818
HLSTAGMTGDELSTS

AHNAK2

5281

Q8IVF2
NGQGSTTRMDHETAS

APC

276

P25054
GDTTMSLHSQGSATT

CLEC1A

16

Q8NC01
HSGLSSNSSMTTREL

SNX20

46

Q7Z614
GTTTANHTMSSGVNT

UNC80

2436

Q8N2C7
ESQMRGSTAVSSSDH

PLEKHG4B

1166

Q96PX9
DQVSMLSGHSSSSLG

STYXL2

766

Q5VZP5
RQAHSSSGMTEGSEE

ZNF646

901

O15015
DMGSSDGETTHDSQI

UPK3A

236

O75631
SGDHSGQATGMSSEV

ZNF536

866

O15090
TVSGMARQDSSSEVG

USP24

1916

Q9UPU5
SATSGVMVRGHSSQL

ZGRF1

946

Q86YA3
SISGEESSHGVIMTR

ZNF215

241

Q9UL58
GSTMSSSLHSDQSQG

ZNF454

156

Q8N9F8
GQMESTETSSSGHRI

PLEKHG1

591

Q9ULL1
MSETGSHGASSTEEV

PIGG

271

Q5H8A4
DMEHSSGESSFESTG

HIVEP2

946

P31629
SETAETFDSMRASGH

SON

1306

P18583
SGTHTVTMVSADGTQ

ZNF76

481

P36508
HSSTLFVRDDGSSMS

TERF2IP

16

Q9NYB0
MSQSSRDTGHLTDSE

USP54

431

Q70EL1
SLGSGSDHVMDAISQ

MYO7A

1311

Q13402