Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	Rab GDP-dissociation inhibitor activity	GDI1 GDI2	1.63e-05	2	81	2	GO:0005093
GeneOntologyMolecularFunction	neuroligin family protein binding	NRXN1 NRXN2	1.61e-04	5	81	2	GO:0097109
GeneOntologyBiologicalProcess	neuron cell-cell adhesion	CDK5R1 NRXN1 NRXN2 RET	4.07e-07	16	82	4	GO:0007158
GeneOntologyBiologicalProcess	myofibril assembly	NRAP MYOM1 MYOM3 MYOM2 PGM5	2.38e-05	86	82	5	GO:0030239
GeneOntologyBiologicalProcess	striated muscle cell development	NRAP MYOM1 MYOM3 MYOM2 PGM5	2.80e-05	89	82	5	GO:0055002
GeneOntologyBiologicalProcess	organelle assembly	WDR19 RAB19 NRAP MYOM1 NRXN1 NRXN2 PWP2 MYOM3 MYOM2 CEP126 GDI2 CDKL1 CNOT2 PGM5 JHY	3.72e-05	1138	82	15	GO:0070925
GeneOntologyBiologicalProcess	actomyosin structure organization	NRAP MYOM1 MYOM3 MYOM2 KANK2 PGM5 PHACTR1	4.67e-05	239	82	7	GO:0031032
GeneOntologyBiologicalProcess	neuroligin clustering involved in postsynaptic membrane assembly	NRXN1 NRXN2	9.32e-05	4	82	2	GO:0097118
GeneOntologyBiologicalProcess	gephyrin clustering involved in postsynaptic density assembly	NRXN1 NRXN2	1.55e-04	5	82	2	GO:0097116
GeneOntologyBiologicalProcess	extraocular skeletal muscle development	MYOM1 MYOM2	1.55e-04	5	82	2	GO:0002074
GeneOntologyCellularComponent	M band	MYOM1 MYOM3 MYOM2	2.42e-04	31	82	3	GO:0031430
GeneOntologyCellularComponent	azurophil granule lumen	MAN2B1 SERPINB3 CTSC GDI2	4.54e-04	91	82	4	GO:0035578
GeneOntologyCellularComponent	vacuolar lumen	CBLIF MAN2B1 SERPINB3 CTSC GDI2	6.80e-04	178	82	5	GO:0005775
GeneOntologyCellularComponent	actin-based cell projection	CBLIF FAT1 FZD3 CDHR2 CFTR TIAM2	7.88e-04	278	82	6	GO:0098858
GeneOntologyCellularComponent	contractile muscle fiber	CDK5R1 NRAP MYOM1 MYOM3 MYOM2 PGM5	9.81e-04	290	82	6	GO:0043292
GeneOntologyCellularComponent	A band	MYOM1 MYOM3 MYOM2	1.12e-03	52	82	3	GO:0031672
GeneOntologyCellularComponent	lysosome	CBLIF RNF167 ATP6AP1 MAN2B1 OSTM1 SERPINB3 CTSC CFTR MITF GDI2	1.25e-03	811	82	10	GO:0005764
GeneOntologyCellularComponent	lytic vacuole	CBLIF RNF167 ATP6AP1 MAN2B1 OSTM1 SERPINB3 CTSC CFTR MITF GDI2	1.25e-03	811	82	10	GO:0000323
GeneOntologyCellularComponent	neuronal cell body	CDK5R1 NRXN1 KALRN FZD3 SEPTIN14 CFTR DYNLT1 RET GDI1 TIAM2	1.56e-03	835	82	10	GO:0043025
GeneOntologyCellularComponent	secretory granule lumen	MAN2B1 SERPINB3 CTSC DYNLT1 GDI2 PDXK	1.75e-03	325	82	6	GO:0034774
GeneOntologyCellularComponent	cytoplasmic vesicle lumen	MAN2B1 SERPINB3 CTSC DYNLT1 GDI2 PDXK	1.89e-03	330	82	6	GO:0060205
GeneOntologyCellularComponent	vesicle lumen	MAN2B1 SERPINB3 CTSC DYNLT1 GDI2 PDXK	1.95e-03	332	82	6	GO:0031983
Domain	RabGDI	GDI1 GDI2	1.90e-05	2	82	2	IPR000806
Domain	IGc2	MYOM1 KALRN LRFN5 MYOM3 CLMP MYOM2 IGSF3	7.79e-05	235	82	7	SM00408
Domain	Ig_sub2	MYOM1 KALRN LRFN5 MYOM3 CLMP MYOM2 IGSF3	7.79e-05	235	82	7	IPR003598
Domain	GDI	GDI1 GDI2	1.14e-04	4	82	2	PF00996
Domain	GDP_dissociation_inhibitor	GDI1 GDI2	1.14e-04	4	82	2	IPR018203
Domain	GATase	GMPS CPS1	1.89e-04	5	82	2	PF00117
Domain	Ig_I-set	MYOM1 KALRN LRFN5 MYOM3 CLMP MYOM2	1.89e-04	190	82	6	IPR013098
Domain	I-set	MYOM1 KALRN LRFN5 MYOM3 CLMP MYOM2	1.89e-04	190	82	6	PF07679
Domain	GATASE	GMPS CPS1	2.82e-04	6	82	2	IPR017926
Domain	GATASE_TYPE_1	GMPS CPS1	2.82e-04	6	82	2	PS51273
Domain	Syndecan	NRXN1 NRXN2	3.94e-04	7	82	2	PF01034
Domain	Syndecan/Neurexin_dom	NRXN1 NRXN2	3.94e-04	7	82	2	IPR027789
Domain	IG	MYOM1 KALRN LRFN5 MYOM3 ERMAP CLMP MYOM2 IGSF3	5.18e-04	421	82	8	SM00409
Domain	Ig_sub	MYOM1 KALRN LRFN5 MYOM3 ERMAP CLMP MYOM2 IGSF3	5.18e-04	421	82	8	IPR003599
Domain	LAM_G_DOMAIN	FAT1 NRXN1 NRXN2	6.16e-04	38	82	3	PS50025
Domain	Laminin_G_2	FAT1 NRXN1 NRXN2	7.17e-04	40	82	3	PF02210
Domain	-	GMPS CPS1	8.38e-04	10	82	2	3.40.50.880
Domain	LamG	FAT1 NRXN1 NRXN2	9.49e-04	44	82	3	SM00282
Domain	Class_I_gatase-like	GMPS CPS1	1.22e-03	12	82	2	IPR029062
Domain	IG_LIKE	MYOM1 KALRN LRFN5 MYOM3 ERMAP CLMP MYOM2 IGSF3	1.40e-03	491	82	8	PS50835
Domain	Ig-like_dom	MYOM1 KALRN LRFN5 MYOM3 ERMAP CLMP MYOM2 IGSF3	1.63e-03	503	82	8	IPR007110
Domain	Quinoprotein_ADH-like_supfam	UTP4 PWP2 GEMIN5	1.63e-03	53	82	3	IPR011047
Domain	Neurexin-like	NRXN1 NRXN2	1.67e-03	14	82	2	IPR003585
Domain	4.1m	NRXN1 NRXN2	1.67e-03	14	82	2	SM00294
Domain	FN3	MYOM1 KALRN LRFN5 MYOM3 MYOM2	1.83e-03	199	82	5	PS50853
Domain	Laminin_G	FAT1 NRXN1 NRXN2	2.12e-03	58	82	3	IPR001791
Domain	FN3_dom	MYOM1 KALRN LRFN5 MYOM3 MYOM2	2.27e-03	209	82	5	IPR003961
Domain	IGv	ERMAP CLMP IGSF3	4.39e-03	75	82	3	SM00406
Domain	PAS	ARNT PDE8B	5.35e-03	25	82	2	PF00989
Domain	PAS_fold	ARNT PDE8B	5.35e-03	25	82	2	IPR013767
Domain	fn3	MYOM1 KALRN MYOM3 MYOM2	5.65e-03	162	82	4	PF00041
Domain	-	FAT1 NRXN1 NRXN2	8.45e-03	95	82	3	2.60.120.200
Domain	-	MYOM1 KALRN LRFN5 MYOM3 ERMAP CLMP MYOM2 IGSF3	8.57e-03	663	82	8	2.60.40.10
Domain	PAS	ARNT PDE8B	8.67e-03	32	82	2	SM00091
Pubmed	Myomesin 3, a novel structural component of the M-band in striated muscle.	MYOM1 MYOM3 MYOM2	1.31e-07	5	83	3	18177667
Pubmed	CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function.	MYOM1 MYOM3 MYOM2	7.28e-07	8	83	3	20215401
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ZNF462 NRXN1 TTC28 NRXN2 CDK12 OGA ERBIN	1.18e-06	225	83	7	12168954
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	ZNF462 NRIP1 RNF167 NRAP MYOM1 KALRN MYOM3 MYOM2 BCL6	2.98e-06	497	83	9	23414517
Pubmed	Bone growth: a study of the grey-lethal and microphthalmic mutants of the mouse.	OSTM1 MITF	5.63e-06	2	83	2	13162938
Pubmed	Mutations in NRXN1 and NRXN2 in a patient with early-onset epileptic encephalopathy and respiratory depression.	NRXN1 NRXN2	5.63e-06	2	83	2	30709877
Pubmed	Spleen cells transmit osteopetrosis in mice.	OSTM1 MITF	5.63e-06	2	83	2	1198094
Pubmed	Regulation of the Coxsackie and adenovirus receptor expression is dependent on cystic fibrosis transmembrane regulator in airway epithelial cells.	CFTR CLMP	5.63e-06	2	83	2	27527752
Pubmed	Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin.	NRXN1 NRXN2	5.63e-06	2	83	2	1621094
Pubmed	Cloning of a brain-type isoform of human Rab GDI and its expression in human neuroblastoma cell lines and tumor specimens.	GDI1 GDI2	5.63e-06	2	83	2	7585614
Pubmed	Heterozygous deletion of α-neurexin I or α-neurexin II results in behaviors relevant to autism and schizophrenia.	NRXN1 NRXN2	5.63e-06	2	83	2	26595880
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CDK5R1 FAT1 MAN2B1 KALRN CDK12 PIK3CD UBR4 MYOM3 GEMIN5 MLLT10 TIAM2 IGSF3	1.21e-05	1105	83	12	35748872
Pubmed	Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior.	NRXN1 NRXN2	1.69e-05	3	83	2	34133920
Pubmed	Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca2+ Influx.	NRXN1 NRXN2	1.69e-05	3	83	2	38891114
Pubmed	FHL2 switches MITF from activator to repressor of Erbin expression during cardiac hypertrophy.	MITF ERBIN	1.69e-05	3	83	2	26025865
Pubmed	The ER-resident ubiquitin-specific protease 19 participates in the UPR and rescues ERAD substrates.	CFTR USP19	1.69e-05	3	83	2	19465887
Pubmed	RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.	GDI1 GDI2	1.69e-05	3	83	2	26240314
Pubmed	Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia.	NRXN1 NRXN2	1.69e-05	3	83	2	21424692
Pubmed	BCL6--regulated by AhR/ARNT and wild-type MEF2B--drives expression of germinal center markers MYBL1 and LMO2.	ARNT BCL6	1.69e-05	3	83	2	25769544
Pubmed	The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice.	NRXN1 NRXN2	1.69e-05	3	83	2	30858964
Pubmed	Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.	NRXN1 NRXN2	1.69e-05	3	83	2	28013231
Pubmed	alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction.	NRXN1 NRXN2	1.69e-05	3	83	2	16406382
Pubmed	Expression patterns of two human genes coding for different rab GDP-dissociation inhibitors (GDIs), extremely conserved proteins involved in cellular transport.	GDI1 GDI2	1.69e-05	3	83	2	7543319
Pubmed	Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion.	NRXN1 NRXN2	1.69e-05	3	83	2	31812984
Pubmed	Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing.	NRXN1 NRXN2	1.69e-05	3	83	2	12036300
Pubmed	β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling.	NRXN1 NRXN2	1.69e-05	3	83	2	26213384
Pubmed	Neurexin gene family variants as risk factors for autism spectrum disorder.	NRXN1 NRXN2	1.69e-05	3	83	2	29045040
Pubmed	Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses.	NRXN1 NRXN2	1.69e-05	3	83	2	31005376
Pubmed	Structural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization.	NRXN1 NRXN2	1.69e-05	3	83	2	38571813
Pubmed	Deletion of β-Neurexins in Mice Alters the Distribution of Dense-Core Vesicles in Presynapses of Hippocampal and Cerebellar Neurons.	NRXN1 NRXN2	1.69e-05	3	83	2	35173587
Pubmed	The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor.	OSTM1 MITF	1.69e-05	3	83	2	17105730
Pubmed	Cloning, characterization, and expression of a novel GDP dissociation inhibitor isoform from skeletal muscle.	GDI1 GDI2	1.69e-05	3	83	2	7513052
Pubmed	Sarcosin (Krp1) in skeletal muscle differentiation: gene expression profiling and knockdown experiments.	MYOM1 MYOM3	1.69e-05	3	83	2	22562206
Pubmed	The Q-rich subdomain of the human Ah receptor transactivation domain is required for dioxin-mediated transcriptional activity.	NRIP1 ARNT	1.69e-05	3	83	2	11551916
Pubmed	Neurexins are differentially expressed in the embryonic nervous system of mice.	NRXN1 NRXN2	1.69e-05	3	83	2	7722633
Pubmed	Regulated Dynamic Trafficking of Neurexins Inside and Outside of Synaptic Terminals.	NRXN1 NRXN2	1.69e-05	3	83	2	26446217
Pubmed	Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity.	NRXN1 NRXN2	1.69e-05	3	83	2	11944992
Pubmed	Alternative splicing of neurexins 1-3 is modulated by neuroinflammation in the prefrontal cortex of a murine model of multiple sclerosis.	NRXN1 NRXN2	1.69e-05	3	83	2	33058888
Pubmed	Important contribution of alpha-neurexins to Ca2+-triggered exocytosis of secretory granules.	NRXN1 NRXN2	1.69e-05	3	83	2	17035546
Pubmed	Neurexins: three genes and 1001 products.	NRXN1 NRXN2	1.69e-05	3	83	2	9448462
Pubmed	Deletion of α-neurexin II results in autism-related behaviors in mice.	NRXN1 NRXN2	1.69e-05	3	83	2	25423136
Pubmed	The globular head domain of titin extends into the center of the sarcomeric M band. cDNA cloning, epitope mapping and immunoelectron microscopy of two titin-associated proteins.	MYOM1 MYOM2	1.69e-05	3	83	2	7505783
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	GMPS MAN2B1 CTSC UBR4 CPS1 GDI1 PDXK	1.90e-05	344	83	7	30333137
Pubmed	Postsynaptic N-methyl-D-aspartate receptor function requires alpha-neurexins.	NRXN1 NRXN2	3.37e-05	4	83	2	14983056
Pubmed	Characteristics of the mouse genomic histamine H1 receptor gene.	MITF RET	3.37e-05	4	83	2	8812432
Pubmed	Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism.	NRXN1 NRXN2	3.37e-05	4	83	2	32706374
Pubmed	p110δ phosphoinositide 3-kinase represses IgE switch by potentiating BCL6 expression.	PIK3CD BCL6	3.37e-05	4	83	2	22422878
Pubmed	Muscle-type creatine kinase interacts with central domains of the M-band proteins myomesin and M-protein.	MYOM1 MYOM2	3.37e-05	4	83	2	12972258
Pubmed	A CRISPR screen targeting PI3K effectors identifies RASA3 as a negative regulator of LFA-1-mediated adhesion in T cells.	PIK3CD BCL6	3.37e-05	4	83	2	35857633
Pubmed	Nestin is expressed during development and in myotendinous and neuromuscular junctions in wild type and desmin knock-out mice.	MYOM1 MYOM2	3.37e-05	4	83	2	10438587
Pubmed	CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins.	NRXN1 NRXN2	3.37e-05	4	83	2	8786425
Pubmed	Deletion of alpha-neurexins does not cause a major impairment of axonal pathfinding or synapse formation.	NRXN1 NRXN2	3.37e-05	4	83	2	17347997
Pubmed	Neurexins cluster Ca2+ channels within the presynaptic active zone.	NRXN1 NRXN2	3.37e-05	4	83	2	32134527
Pubmed	cDNA cloning, expression, mutagenesis, intracellular localization, and gene chromosomal assignment of mouse 5-lipoxygenase.	MITF RET	3.37e-05	4	83	2	7629107
Pubmed	Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins.	NRXN1 NRXN2	3.37e-05	4	83	2	35385735
Pubmed	Neurexins regulate presynaptic GABAB-receptors at central synapses.	NRXN1 NRXN2	3.37e-05	4	83	2	33888718
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	WDR19 TBRG4 NRXN2 CDK12 CEP126 OGA TIAM2 IGSF3	3.95e-05	529	83	8	14621295
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	GMPS UTP4 QRICH1 KANK2 GDI2 PDXK SACM1L	4.95e-05	400	83	7	35013556
Pubmed	Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins.	NRXN1 NRXN2	5.60e-05	5	83	2	28472659
Pubmed	Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.	NRXN1 NRXN2	5.60e-05	5	83	2	36709330
Pubmed	Localization of the synapsin II (SYN2) gene to human chromosome 3 and mouse chromosome 6.	MITF RET	5.60e-05	5	83	2	8530057
Pubmed	Placenta to cartilage: direct conversion of human placenta to chondrocytes with transformation by defined factors.	MITF BCL6	5.60e-05	5	83	2	22833560
Pubmed	GDI-1 preferably interacts with Rab10 in insulin-stimulated GLUT4 translocation.	GDI1 GDI2	5.60e-05	5	83	2	19570034
Pubmed	Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum.	NRXN1 NRXN2	5.60e-05	5	83	2	20537373
Pubmed	Neuroligins and neurexins link synaptic function to cognitive disease.	NRXN1 NRXN2	5.60e-05	5	83	2	18923512
Pubmed	Characterization of novel Rab6-interacting proteins involved in endosome-to-TGN transport.	GDI1 GDI2	5.60e-05	5	83	2	11929610
Pubmed	Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Ibeta gene expression followed by late-onset neuromotor deterioration.	NRXN1 NRXN2	5.60e-05	5	83	2	9223334
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	GMPS BPHL NRXN1 KALRN UBR4 ERBIN CNOT2 PDXK IGSF3 SACM1L PHACTR1	8.28e-05	1139	83	11	36417873
Pubmed	Establishment of cardiac cytoarchitecture in the developing mouse heart.	MYOM1 MYOM2	8.39e-05	6	83	2	16337936
Pubmed	PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells.	ARNT PIK3CD	8.39e-05	6	83	2	23183047
Pubmed	Neurexin-Neuroligin Synaptic Complex Regulates Schizophrenia-Related DISC1/Kal-7/Rac1 "Signalosome".	NRXN1 KALRN	8.39e-05	6	83	2	26078884
Pubmed	Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.	NRXN1 NRXN2	8.39e-05	6	83	2	12827191
Pubmed	Construction of a transcription map of a 300 kb region around the human G6PD locus by direct cDNA selection.	ATP6AP1 GDI1	8.39e-05	6	83	2	8281148
Pubmed	Structures, alternative splicing, and neurexin binding of multiple neuroligins.	NRXN1 NRXN2	8.39e-05	6	83	2	8576240
Pubmed	Presynaptic α2δ-2 Calcium Channel Subunits Regulate Postsynaptic GABAA Receptor Abundance and Axonal Wiring.	NRXN1 NRXN2	8.39e-05	6	83	2	30683685
Pubmed	The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function.	GDI1 GDI2	8.39e-05	6	83	2	11809807
Pubmed	Genomic analysis of mouse retinal development.	RNF167 CDK5R1 NRXN2 FZD3 ZNF429 DYNLT1 OGA ERBIN PDXK PHACTR1	1.41e-04	1006	83	10	15226823
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	RAB19 FAT1 ATP6AP1 KALRN CDHR2 SERPINB3 CTSC GDI2 TIAM2 PDXK	1.53e-04	1016	83	10	19056867
Pubmed	Tagging genes with cassette-exchange sites.	ZNF462 CDK12 UBR4 ZNF429 GEMIN5 QRICH1	1.55e-04	335	83	6	15741177
Pubmed	Transcriptional organization of a 450-kb region of the human X chromosome in Xq28.	ATP6AP1 GDI1	1.56e-04	8	83	2	8248200
Pubmed	Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.	NRXN1 NRXN2	1.56e-04	8	83	2	30871858
Pubmed	Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.	NRXN1 NRXN2	1.56e-04	8	83	2	37591863
Pubmed	Differential interactions of cerebellin precursor protein (Cbln) subtypes and neurexin variants for synapse formation of cortical neurons.	NRXN1 NRXN2	2.00e-04	9	83	2	21356198
Pubmed	Molecular self-avoidance in synaptic neurexin complexes.	NRXN1 NRXN2	2.00e-04	9	83	2	34919427
Pubmed	PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor.	NRXN1 NRXN2	2.00e-04	9	83	2	9707552
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	TRAPPC13 ARNT SERPINB3 UBR4 QRICH1 CPS1 KANK2 CDKL1 SACM1L	2.07e-04	857	83	9	25609649
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	FAT1 MYOM1 CDK12 UBR4 GEMIN5 KANK2	2.31e-04	361	83	6	26167880
Pubmed	Chromosomal localisation, inducibility, tissue-specific expression and strain differences in three murine peroxisome-proliferator-activated-receptor genes.	MITF RET	2.50e-04	10	83	2	7588749
Pubmed	Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data.	GMPS CPS1	2.50e-04	10	83	2	20659789
Pubmed	Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology.	MYOM1 MYOM2	2.50e-04	10	83	2	20368620
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	ZNF462 NRIP1 UTP4 OSBPL11 QRICH1 ERBIN CNOT2	3.00e-04	536	83	7	15840001
Pubmed	Neurodevelopment. Parasympathetic neurons originate from nerve-associated peripheral glial progenitors.	MITF RET	3.05e-04	11	83	2	24925909
Pubmed	SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins.	NRXN1 NRXN2	3.05e-04	11	83	2	32973045
Pubmed	Aebp2 as an epigenetic regulator for neural crest cells.	MITF RET	3.05e-04	11	83	2	21949878
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	ZNF462 NRIP1 UTP4 OSBPL11 QRICH1 ERBIN CNOT2	3.07e-04	538	83	7	10512203
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	GMPS TRAPPC13 ARNT SERPINB3 UBR4 QRICH1 OGA GDI1 CNOT2 USP19 SACM1L	3.12e-04	1327	83	11	32694731
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	NRXN1 KALRN GDI1 GDI2 ERBIN	3.45e-04	251	83	5	27507650
Pubmed	Planar cell polarity genes control the connectivity of enteric neurons.	FZD3 RET	3.66e-04	12	83	2	23478408
Pubmed	Molecular diversity of myofibrillar proteins: gene regulation and functional significance.	MYOM1 MYOM2	3.66e-04	12	83	2	8618961
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ZNF462 NRXN1 KALRN UBR4 KANK2 GDI1 GDI2 ERBIN PHACTR1	4.85e-04	963	83	9	28671696
Cytoband	5q12.3	TRAPPC13 ERBIN	4.85e-04	18	83	2	5q12.3
Cytoband	22q12.1	CCDC117 TTC28	1.55e-03	32	83	2	22q12.1
Cytoband	11q24.1	CLMP JHY	2.06e-03	37	83	2	11q24.1
GeneFamily	Fibronectin type III domain containing\|I-set domain containing\|Myosin binding proteins	MYOM1 MYOM3 MYOM2	1.83e-06	8	59	3	658
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	MYOM1 KALRN LRFN5 MYOM3 CLMP MYOM2	1.39e-05	161	59	6	593
GeneFamily	Cadherin related	FAT1 CDHR2 RET	2.17e-05	17	59	3	24
GeneFamily	Fibronectin type III domain containing	MYOM1 KALRN LRFN5 MYOM3 MYOM2	1.74e-04	160	59	5	555
GeneFamily	Cyclin dependent kinases	CDK12 CDKL1	3.24e-03	26	59	2	496
GeneFamily	Immunoglobulin like domain containing	MYOM3 CLMP MYOM2 IGSF3	3.62e-03	193	59	4	594
Coexpression	RAO_BOUND_BY_SALL4_ISOFORM_A	FAT1 SERPINB3 CFTR MITF POLQ SACM1L	3.58e-05	194	83	6	M2517
Coexpression	MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN	ARNT TBRG4 CTSC ERMAP MLLT10 KANK2 ERBIN USP19 PGM5	3.91e-05	519	83	9	M3395
Coexpression	GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP	ZNF462 TRAPPC13 NRIP1 CDK5R1 OSTM1 CDK12	4.01e-05	198	83	6	M4249
Coexpression	GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP	NRIP1 NRXN1 PIK3CD PDE8B RET OGA	4.12e-05	199	83	6	M4444
Coexpression	GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN	NRIP1 MYOM1 TTC28 KANK2 GDI1 GRAP	4.24e-05	200	83	6	M7518
Coexpression	MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN	ARNT TBRG4 CTSC ERMAP MLLT10 KANK2 ERBIN USP19 PGM5	5.55e-05	543	83	9	MM997
Coexpression	RAO_BOUND_BY_SALL4_ISOFORM_A	FAT1 SERPINB3 CFTR MITF POLQ SACM1L	5.56e-05	210	83	6	MM958
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	NRAP MYOM1 PDE8B MITF MYOM3 MYOM2 PGM5 PHACTR1	3.09e-09	194	83	8	c3535f7cc0076653c72db582047cff053c322397
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-35\|World / Primary Cells by Cluster	ZNF462 CDK5R1 NRXN1 TTC28 FZD3 CLMP OGA TIAM2	3.63e-09	198	83	8	de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	NRAP MYOM1 PDE8B MITF MYOM3 MYOM2 PGM5	6.31e-08	188	83	7	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	NRAP MYOM1 MITF MYOM3 MYOM2 PGM5 PHACTR1	7.04e-08	191	83	7	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	NRAP MYOM1 PDE8B MITF MYOM2 PGM5 PHACTR1	7.83e-08	194	83	7	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Neuronal-Immature_CPNs\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	ZNF462 CDK5R1 NRXN1 TTC28 CLMP CNOT2 IGSF3	8.99e-08	198	83	7	4e598aab92141e7d32ec963291ddeed14a21beba
ToppCell	RV-11._Adipocyte\|RV / Chamber and Cluster_Paper	NRIP1 PDE8B CLMP ACSF2 OGA PDXK	1.03e-06	178	83	6	278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT1 NRXN1 KALRN CFTR MYOM2 CPS1	1.25e-06	184	83	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT1 NRXN1 KALRN CFTR MYOM2 CPS1	1.25e-06	184	83	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT1 NRXN1 KALRN CFTR MYOM2 CPS1	1.25e-06	184	83	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	NRAP MYOM1 MITF MYOM3 MYOM2 PHACTR1	1.25e-06	184	83	6	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	NRAP MYOM1 MITF MYOM3 MYOM2 PHACTR1	1.29e-06	185	83	6	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	RA-11._Adipocyte\|World / Chamber and Cluster_Paper	NRIP1 PDE8B CLMP ACSF2 OGA PDXK	1.42e-06	188	83	6	4dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP MYOM1 KALRN MYOM3 MYOM2 PGM5	1.51e-06	190	83	6	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	NRAP MYOM1 MITF MYOM3 MYOM2 PHACTR1	1.60e-06	192	83	6	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	NRAP MYOM1 MITF MYOM3 MYOM2 PHACTR1	1.76e-06	195	83	6	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	NRAP MYOM1 MITF MYOM3 MYOM2 PHACTR1	1.76e-06	195	83	6	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	PIK3CD CFTR ERCC6L2 ZNF429 CEP126	3.31e-06	122	83	5	a2f343962069253a08faa80fd70723b8488a99ec
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CFTR ERCC6L2 ZNF429 CEP126 USP19	1.48e-05	166	83	5	f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP MYOM1 MYOM3 MYOM2 PGM5	1.66e-05	170	83	5	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	FLU-Healthy-5\|Healthy / Virus stimulation, Condition and Cluster	TRAPPC13 RAB19 CDHR2 ERMAP IGSF3	1.81e-05	173	83	5	8c218ec1ba927e9312f3df5f312395e907ab64ab
ToppCell	FLU-Healthy-5\|FLU / Virus stimulation, Condition and Cluster	TRAPPC13 RAB19 CDHR2 ERMAP IGSF3	1.81e-05	173	83	5	bd4f06d971f9d138749094047c9337dfbaf5da31
ToppCell	LV-11._Adipocyte\|LV / Chamber and Cluster_Paper	NRIP1 PDE8B CLMP ACSF2 PDXK	1.81e-05	173	83	5	c2d3fcb3de71015d03d14c63450853d2b03ffa71
ToppCell	RV-11._Adipocyte\|World / Chamber and Cluster_Paper	PDE8B CLMP ACSF2 OGA PDXK	2.02e-05	177	83	5	f0edf04930692418953e4f00a917257804ec0ffd
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK5R1 TTC28 KALRN ZGRF1 PGM5	2.25e-05	181	83	5	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP MYOM1 MYOM3 MYOM2 PGM5	2.25e-05	181	83	5	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	LA-11._Adipocyte\|World / Chamber and Cluster_Paper	PDE8B CLMP ACSF2 OGA PDXK	2.37e-05	183	83	5	b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCell	LA-11._Adipocyte\|LA / Chamber and Cluster_Paper	PDE8B CLMP ACSF2 OGA PDXK	2.37e-05	183	83	5	3f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP MYOM1 MYOM3 MYOM2 PGM5	2.43e-05	184	83	5	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP MYOM1 MYOM3 MYOM2 PGM5	2.49e-05	185	83	5	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	MYOM1 MITF MYOM3 MYOM2 PHACTR1	2.69e-05	188	83	5	0758b474457efa36488e0195f7357100f4b6a090
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	MYOM1 MITF MYOM3 MYOM2 PHACTR1	2.76e-05	189	83	5	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	MYOM1 MITF MYOM3 MYOM2 PHACTR1	2.76e-05	189	83	5	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	FAT1 NRAP MYOM1 MYOM2 PHACTR1	2.83e-05	190	83	5	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	MYOM1 MITF MYOM3 MYOM2 PHACTR1	2.83e-05	190	83	5	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	MYOM1 MITF MYOM3 MYOM2 PHACTR1	2.83e-05	190	83	5	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	MYOM1 MITF MYOM3 MYOM2 PHACTR1	2.90e-05	191	83	5	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	NRAP MYOM1 MYOM3 MYOM2 PHACTR1	3.05e-05	193	83	5	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	facs-Thymus-nan-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRIP1 BCL6 OGA ERBIN CNOT2	3.13e-05	194	83	5	f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCell	facs-Thymus-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRIP1 BCL6 OGA ERBIN CNOT2	3.13e-05	194	83	5	cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCell	facs-Thymus-nan-3m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRIP1 BCL6 OGA ERBIN CNOT2	3.13e-05	194	83	5	66c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRXN1 KALRN FZD3 LRFN5 PHACTR1	3.21e-05	195	83	5	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn\|World / Primary Cells by Cluster	ZNF462 CDK5R1 TTC28 CLMP TIAM2	3.29e-05	196	83	5	9401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYOM1 KALRN LRFN5 MYOM2 PGM5	3.29e-05	196	83	5	9830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Immature_CPNs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	ZNF462 TTC28 DYNLT1 CLMP TIAM2	3.45e-05	198	83	5	32d58379a89be19b6b1a494bf033416546771c19
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYOM1 KALRN MYOM2 KANK2 PGM5	3.45e-05	198	83	5	c12e7511628db819a52959bb68580e27c00c2e41
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	WDR19 UTP4 MITF MYOM2 BCL6	3.45e-05	198	83	5	cc2b5b632e73e44bb60050f0db10d8f0dbb859fa
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYOM1 MYOM2 KANK2 PGM5 PHACTR1	3.45e-05	198	83	5	22e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal-Neurons\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	CDK5R1 TTC28 DYNLT1 CLMP GDI1	3.53e-05	199	83	5	ae575ed7582f2a4218f6cbcbf5f7f0ce7a5bc26b
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	CTSC PWP2 MITF ERMAP USP43	3.62e-05	200	83	5	fe22f7c97f4e37dfa7881d0f1d9245c1237d873b
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Interneuron\|5w / Sample Type, Dataset, Time_group, and Cell type.	CDK5R1 LRFN5 GDI1 TIAM2 IGSF3	3.62e-05	200	83	5	c7e33057466915d4e2b34f2062b22d9cdffa69dc
ToppCell	Control-Neu_0\|World / 5 Neutrophil clusters in COVID-19 patients	PDE8B MYOM3 OGA ERBIN	7.52e-05	120	83	4	840d0ac995e2fa41996514753e4e03c4aa4a26d0
ToppCell	Control-Fibroblasts-Mesothelial_FB\|Control / group, cell type (main and fine annotations)	NRXN1 LRFN5 CLMP RET	1.33e-04	139	83	4	e769beb031b262dd92c9605b07dbf3c29fb82520
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma-3\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	RAB19 CDHR2 CFTR HNF4G	1.60e-04	146	83	4	e55b4acecf4e363b5afa287c747c2e58c4597f3a
ToppCell	Club_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	FAT1 SERPINB3 TDRD6 RET	1.64e-04	147	83	4	5a824c89e4d045af465d7333275f8191fb29b041
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	RAB19 CDHR2 CFTR HNF4G	1.73e-04	149	83	4	92a8931a51db619fb5f0638d319c02e7838f6559
ToppCell	ASK452-Epithelial-Type_2\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	SLC25A35 PDE8B GEMIN5 IGSF3	2.07e-04	156	83	4	e2b8d65c38cedb8ec6c3c1b138957145af931c51
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCDC117 ZNF462 CDK5R1 ZGRF1	2.17e-04	158	83	4	6d2709b387945c015faa223c20d22b52a4082140
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MITF ERMAP GEMIN5 BCL6	2.27e-04	160	83	4	70f3637dd0bcfcef421aa114f946fff0048f192e
ToppCell	3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF462 SLC25A35 ZNF300 CPS1	2.39e-04	162	83	4	768a566e76923323c1f197f60bab472a8784490b
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RAB19 SERPINB3 LRFN5 CTSC	2.44e-04	163	83	4	22fa5d017ff796394394d952ec151e2d1beb8248
ToppCell	LV-11._Adipocyte\|World / Chamber and Cluster_Paper	NRIP1 PDE8B ACSF2 PDXK	2.62e-04	166	83	4	7e5852891714465c6228c9f955fd511ec79d0e02
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRAP MYOM1 FZD3 MYOM2	2.80e-04	169	83	4	88aa2246ede582c2e11de63228d76f520889ecb3
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRAP MYOM1 FZD3 MYOM2	2.80e-04	169	83	4	a6a5b00912b653fad2ca7f096deaf35c9ef85e5b
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRAP MYOM1 FZD3 MYOM2	2.80e-04	169	83	4	42a9b8c77d2a4d68b01e4db38f8a1af53c9c814f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYOM1 KALRN MYOM2 RET	2.87e-04	170	83	4	99dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYOM1 KALRN MYOM2 RET	2.87e-04	170	83	4	3a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYOM1 KALRN MYOM2 RET	2.87e-04	170	83	4	cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	MYOM1 KALRN MYOM2 PGM5	3.06e-04	173	83	4	a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCell	Mild/Remission-B_naive-8\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TTC28 OGA KANK2 PHACTR1	3.06e-04	173	83	4	694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NRAP FZD3 SERPINB3 PDE8B	3.13e-04	174	83	4	3f0a5ce074675d57d479fa069385a1b3071e884e
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	SERPINB3 PDE8B CFTR HNF4G	3.13e-04	174	83	4	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	COVID-19-kidney-REN+Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRXN2 KALRN PDE8B RET	3.13e-04	174	83	4	8393f0b43c767839c1630bcb952d62b42efc788d
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-stromal_related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRXN2 MITF CLMP BCL6	3.20e-04	175	83	4	b8995e7ada85ba959f06264a0295b61e390c4e6c
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-stromal_related-T_reticular\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRXN2 MITF CLMP BCL6	3.20e-04	175	83	4	7ae76bd3b4f610b2f98716a4456437cd3696b686
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP MYOM1 MYOM3 PGM5	3.27e-04	176	83	4	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-nan\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FZD3 CDHR2 PDE8B ERBIN	3.27e-04	176	83	4	1dd54bfaa58541de51e5a8328651d390833bd480
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KALRN LRFN5 CLMP BCL6	3.41e-04	178	83	4	d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	SERPINB3 PDE8B CFTR HNF4G	3.48e-04	179	83	4	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	CD8+_Memory_T_cell-FLU-5\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	RAB19 CDHR2 ERMAP IGSF3	3.48e-04	179	83	4	7f18dffa85285599662edbcd3f32ab42672bffb8
ToppCell	NS-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFTR RET KANK2 CHST3	3.48e-04	179	83	4	65a96bee7bc28f5bfc20f0fd92bcc0ab2eb5e06c
ToppCell	RA-11._Adipocyte\|RA / Chamber and Cluster_Paper	PDE8B ACSF2 OGA PDXK	3.56e-04	180	83	4	d48a3d27357f7d184132a6805950f93080146b59
ToppCell	RV\|World / Chamber and Cluster_Paper	NRAP MYOM3 MYOM2 PHACTR1	3.63e-04	181	83	4	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN2 ERMAP PGM5 CHST3	3.71e-04	182	83	4	b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCell	facs-Heart-LA-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP MYOM1 MYOM3 MYOM2	3.79e-04	183	83	4	905e1e9be0f15be184447df04b134a6aa8279074
ToppCell	facs-Heart-LA-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP MYOM1 MYOM3 MYOM2	3.79e-04	183	83	4	92eed783347a372b850de3189e72525082390014
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFTR MYOM3 CPS1 HNF4G	3.79e-04	183	83	4	0d21befacefc6c597e7b501ed41b7fe9385a78df
ToppCell	Epithelial-lung_goblet_cell\|World / Lineage, Cell type, age group and donor	SERPINB3 PDE8B CFTR HNF4G	3.79e-04	183	83	4	940cbe298e9c53b5622af09264586ed823d3141f
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	ZNF462 FAT1 MYOM3 HNF4G	3.87e-04	184	83	4	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	wk_20-22-Epithelial-PNS-intermediate_Schwann\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MYOM1 NRXN1 FZD3 CHST3	3.87e-04	184	83	4	4e3ba64692868563a579902aa9c6f88cab5bce26
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBRG4 ACSF2 CDKL1 PGM5	3.95e-04	185	83	4	bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCell	Control-Myeloid-Macrophage_Alveolar\|World / Disease state, Lineage and Cell class	NRIP1 CTSC MITF OSBPL11	3.95e-04	185	83	4	85cb81759589a26d83676cffbf2bc37399683c10
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NRAP NRXN2 ERMAP PGM5	3.95e-04	185	83	4	59acaf025353405948dc34ccccf37ec5c08ea903
ToppCell	Mild_COVID-19-Epithelial-AT1/AT2\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	FAT1 CFTR RET KANK2	3.95e-04	185	83	4	c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF462 FAT1 MYOM3 HNF4G	4.03e-04	186	83	4	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	Control-Endothelial-Endothelial-Vein\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KALRN CTSC PGM5 PHACTR1	4.03e-04	186	83	4	92092f11ecce22c14f244e42c499af0822977e6f
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT1 MYOM1 KALRN KANK2	4.03e-04	186	83	4	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	CDK12 OSBPL11 HNF4G ERBIN	4.03e-04	186	83	4	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	TTC28 KALRN TDRD6 RET	4.03e-04	186	83	4	a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KALRN LRFN5 USP43 PHACTR1	4.11e-04	187	83	4	f18628ffc7ff7c762b8339ba8822cf0c3157f469
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA	WDR19 ARNT MAN2B1 ERMAP AZI2 BCL6 OGA	4.11e-06	181	82	7	1077_UP
Drug	Ethoxyquin [91-53-2]; Down 200; 18.4uM; HL60; HT_HG-U133A	CDK5R1 CDHR2 RET MLLT10 CPS1 OGA USP19	7.17e-06	197	82	7	2559_DN
Disease	breast cancer, ovarian carcinoma	NRIP1 TTC28 MLLT10 HNF4G	3.09e-06	37	80	4	EFO_0001075, MONDO_0007254
Disease	urinary pH measurement	KALRN BCL6	7.22e-05	5	80	2	EFO_0010136
Disease	urinary albumin to creatinine ratio	FAT1 MYOM1 CTSC MLLT10 CPS1	1.29e-04	179	80	5	EFO_0007778
Disease	handedness	BPHL TTC28 UTP4 HNF4G	2.02e-04	106	80	4	EFO_0009902
Disease	plasminogen activator inhibitor 1 measurement	UBR4 MITF MYOM2	4.31e-04	54	80	3	EFO_0004792
Disease	melanoma	ARNT UBR4 MITF RET MLLT10	5.80e-04	248	80	5	C0025202
Disease	thalamus volume change measurement	FAT1 LRFN5	6.47e-04	14	80	2	EFO_0021496
Disease	Alzheimer disease, Cognitive impairment	NRXN1 HNF4G	7.45e-04	15	80	2	HP_0100543, MONDO_0004975
Disease	cancer (implicated_via_orthology)	PIK3CD RET KANK2 GDI1 GDI2	8.22e-04	268	80	5	DOID:162 (implicated_via_orthology)
Disease	schizophrenia (implicated_via_orthology)	NRXN1 CTSC CHST3	8.47e-04	68	80	3	DOID:5419 (implicated_via_orthology)
Disease	serine measurement, amino acid measurement	SEPTIN14 CPS1	9.61e-04	17	80	2	EFO_0005134, EFO_0009774
Disease	Lymphoma, Follicular	ATP6AP1 BCL6	1.34e-03	20	80	2	C0024301
Disease	coronary artery disease	NRXN1 CDK12 CFTR MITF USP43 QRICH1 KANK2 PDXK CHST3 PHACTR1	1.43e-03	1194	80	10	EFO_0001645
Disease	Bronchiectasis	PIK3CD CFTR	1.62e-03	22	80	2	C0006267
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	MITF RET	1.77e-03	23	80	2	C1708353
Disease	pain	NRXN1 CPS1 CHST3 PHACTR1	2.01e-03	196	80	4	EFO_0003843
Disease	gout	FAT1 NRXN2 CFTR MITF	2.01e-03	196	80	4	EFO_0004274
Disease	FEV change measurement, response to zileuton	NRXN1 CPS1	2.09e-03	25	80	2	EFO_0005921, EFO_0007676
Disease	Squamous cell carcinoma of esophagus	FAT1 SERPINB3 GDI2	2.22e-03	95	80	3	C0279626
Disease	red blood cell density measurement	ZNF462 KALRN CDK12 PDE8B MITF ZNF429 CPS1 HNF4G	2.65e-03	880	80	8	EFO_0007978

Protein segments in the cluster

Peptide	Gene	Start	Entry
SNNIHTYQGKTLQGT	nan	116	A8MT66
TSSVGREQVNKAYHA	AZI2	81	Q9H6S1
YHNINADQSKGISSS	ARNT	561	P27540
GQQNYSSATLSHKDV	ERBIN	1231	Q96RT1
SNTKNYTGESQAKHV	CCDC117	226	Q8IWD4
SSNSVVHAETKLQNY	CDK12	1426	Q9NYV4
AATVGHYTAVQNSKN	CDK5R1	21	Q15078
DKGNSTHSRNNSYAV	CFTR	891	P13569
SVSVNYGDQVQHFKV	GRAP	96	Q13588
KGATLSHYNIVNNSN	ACSF2	271	Q96CM8
HFKSGVYTETQQNTI	RAB19	36	A4D1S5
AVAGTYQNTAQTVHI	QRICH1	401	Q2TAL8
HKVTKVSNVYSQTNG	LRFN5	561	Q96NI6
GQQFAVGSHVYSVAK	PGM5	461	Q15124
VTVQENSAAKTYVGH	FAT1	41	Q14517
YISNSAQSNGAVVKE	NRXN1	436	P58400
HNVAAQGKYIAIVST	GDI2	341	P50395
SQFVYHINTHGSTKN	JHY	511	Q6NUN7
QSGVAYKAGNEQSVH	NRAP	746	Q86VF7
LSGNEYVFTKNVHQS	PDE8B	516	O95263
AGHYASQQIKQISTQ	KALRN	381	O60229
YISNSAQSNGAVVKE	NRXN2	1676	Q9P2S2
GVHNDVSKFNTQNYA	NRIP1	521	P48552
YISNSAQSNGAVVKE	NRXN1	1441	Q9ULB1
GNAHSLLQTKNYSEV	OSTM1	206	Q86WC4
QYKIAANQASVISHQ	HNF4G	386	Q14541
TASFSAQQHKGSLQV	MEI1	1016	Q5TIA1
NNTGYINASHIKVSV	PTPN21	946	Q16825
YTAQKSGQQGVAQHH	PHACTR1	261	Q9C0D0
TNKQAFITAQNHGYA	CPS1	326	P31327
FSVAANGSVYINQSK	CDHR2	866	Q9BYE9
QNVAVQDSGTYSCHV	IGSF3	906	O75054
SSINNIAENVNHKTY	CBLIF	371	P27352
GIQVKVINAAHSFYN	GMPS	291	P49915
HQQVFSTNQYFSGVK	CDKL1	226	Q00532
LSNVTSNYDFVGQHK	CEP126	546	Q9P2H0
GTYTTNKTKNNHVSD	POLQ	1296	O75417
ESAIGGNAYQHSKVN	DYNLT1	26	P63172
KVGTASENVYVNIAH	CTSC	141	P53634
HGAITNTKVQYRVSA	BCL6	681	P41182
AQQAKGSSVHVLYST	MAN2B1	341	O00754
SIQATIQNVHSAKDY	ITIH6	336	Q6UXX5
QYKASTVTQGSHNKA	FZD3	271	Q9NPG1
NIADSNGNTALHYSV	KANK2	661	Q63ZY3
HNVAAQGKYIAIAST	GDI1	341	P31150
YIHSNQNVIGSSKAE	ERCC6L2	1131	Q5T890
SAKVAVNGVQLHYQQ	BPHL	41	Q86WA6
QAQAASEIAVGHQYK	SLC25A35	131	Q3KQZ1
EQIVHYNGSKASFVQ	SACM1L	241	Q9NTJ5
QETQAAAHNYATKQS	CPHXL	111	A0A1W2PPM1
AAHNYATKQSLSGAQ	CPHXL	116	A0A1W2PPM1
AYGKLSFHQTQVSQR	TBRG4	301	Q969Z0
HTFTVNAASGEQYKL	OSBPL11	121	Q9BXB4
AGVISFYNVTNKSHI	ERMAP	366	Q96PL5
ASGTSAGVHVYNVKQ	UTP4	501	Q969X6
KSSHFYSNVGLQIQT	SEPTIN14	81	Q6ZU15
QFIDYGNVSVVHTNK	TDRD6	1386	O60522
QYSSRQVAHSGAKAS	OGA	396	O60502
AQKAGYGAAVVHNVN	RNF167	101	Q9H6Y7
SKDGNYSVHQNSHTR	TEX49	41	A0A1B0GTD5
QTQSGKVNNIYLSTH	WDR19	621	Q8NEZ3
QVTENTTGKAATYHV	SERPINB3	61	P29508
DAVNSVQFSNHTGYA	PDXK	36	O00764
NANFQEVSAHTSSGK	MLLT10	291	P55197
NEGNQKVVITYSSRH	CLMP	56	Q9H6B4
IQKNTQAAHDGSGIY	CHST3	401	Q7LGC8
GHTLSEKRNYQVTNS	CNOT2	6	Q9NZN8
SKASQFTGYAQHDAQ	USP19	576	O94966
VSKYGSQFQGNSQHD	USP43	171	Q70EL4
SQYTLQGSKNHSNTI	TIAM2	6	Q8IVF5
QYLSTTLANKHANQV	MITF	141	O75030
QSESYVLKQQGHFNS	PWP2	361	Q15269
ASGSNNAVIYVHNLK	GEMIN5	601	Q8TEQ6
YDFVHVIQQGKTNNS	PIK3CD	936	O00329
EVHSNGSVAYFNASQ	ATP6AP1	346	Q15904
QAFSGINVQYKLHSS	RET	431	P07949
FSNSNTYKTRHTGIN	ZNF253	156	O75346
ASQASTHGNLAVAYQ	TTC28	551	Q96AY4
HYSGVSQNIRSKAQI	ZGRF1	241	Q86YA3
NQSSALTNHKRIYVG	ZNF429	211	Q86V71
YGSSTNLKDHQVSNT	ZNF462	801	Q96JM2
SSYISVHNDSNQVVK	TRAPPC13	81	A5PLN9
VYNAQQIKHRLNSTG	UBR4	2311	Q5T4S7
VNSKTVTEASGHKYN	ZNF300	151	Q96RE9
YTFQLQDGKATNHST	MYOM1	1316	P52179
ATNAHGQVSTNAAVV	MYOM2	231	P54296
ATYTVRVKNAHGQAS	MYOM3	226	Q5VTT5