Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction3'-5' DNA helicase activity

NAV2 ERCC3

1.79e-0416252GO:0043138
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

MYO18A NAV2 ERCC3

5.22e-04127253GO:0008094
GeneOntologyMolecularFunctionhelicase activity

NAV2 ERCC3 EIF4A3

9.84e-04158253GO:0004386
GeneOntologyBiologicalProcessacrosomal vesicle exocytosis

RIMS1 STXBP1

6.31e-0510252GO:0060478
GeneOntologyBiologicalProcesspresynaptic dense core vesicle exocytosis

RIMS1 STXBP1

6.31e-0510252GO:0099525
GeneOntologyBiologicalProcessneuronal dense core vesicle exocytosis

RIMS1 STXBP1

9.24e-0512252GO:0099011
GeneOntologyBiologicalProcessendomembrane system organization

MYO18A TMF1 MIA3 RIMS1 STXBP1 SYTL4

1.22e-04672256GO:0010256
GeneOntologyBiologicalProcessvesicle organization

MYO18A TMF1 MIA3 RIMS1 STXBP1

1.23e-04415255GO:0016050
GeneOntologyBiologicalProcessregulation of synaptic vesicle priming

RIMS1 STXBP1

1.27e-0414252GO:0010807
GeneOntologyBiologicalProcessdense core granule exocytosis

RIMS1 STXBP1

1.47e-0415252GO:1990504
GeneOntologyBiologicalProcesssecretion by cell

MYO18A TMF1 NEO1 MIA3 RIMS1 STXBP1 SYTL4

2.02e-041064257GO:0032940
GeneOntologyBiologicalProcessregulation of secretion by cell

MYO18A TMF1 NEO1 RIMS1 STXBP1 SYTL4

2.06e-04740256GO:1903530
GeneOntologyBiologicalProcessregulation of synaptic vesicle fusion to presynaptic active zone membrane

RIMS1 STXBP1

2.64e-0420252GO:0031630
GeneOntologyBiologicalProcessregulation of synaptic vesicle membrane organization

RIMS1 STXBP1

2.64e-0420252GO:1901632
GeneOntologyBiologicalProcessregulation of secretion

MYO18A TMF1 NEO1 RIMS1 STXBP1 SYTL4

3.16e-04801256GO:0051046
GeneOntologyBiologicalProcessexport from cell

MYO18A TMF1 NEO1 MIA3 RIMS1 STXBP1 SYTL4

3.31e-041153257GO:0140352
GeneOntologyBiologicalProcesscalcium ion-regulated exocytosis of neurotransmitter

RIMS1 STXBP1

4.16e-0425252GO:0048791
GeneOntologyBiologicalProcesssecretion

MYO18A TMF1 NEO1 MIA3 RIMS1 STXBP1 SYTL4

4.68e-041221257GO:0046903
GeneOntologyBiologicalProcessdense core granule localization

RIMS1 STXBP1

5.23e-0428252GO:0032253
GeneOntologyBiologicalProcessmembrane organization

MYO18A GPHN MIA3 RIMS1 STXBP1 SYTL4

6.39e-04914256GO:0061024
GeneOntologyBiologicalProcesssynaptic vesicle fusion to presynaptic active zone membrane

RIMS1 STXBP1

6.42e-0431252GO:0031629
GeneOntologyBiologicalProcesssynaptic vesicle priming

RIMS1 STXBP1

6.42e-0431252GO:0016082
GeneOntologyBiologicalProcessvesicle fusion to plasma membrane

RIMS1 STXBP1

6.84e-0432252GO:0099500
GeneOntologyBiologicalProcesssecretory granule localization

RIMS1 STXBP1

7.73e-0434252GO:0032252
GeneOntologyBiologicalProcessregulation of vesicle fusion

RIMS1 STXBP1

8.19e-0435252GO:0031338
GeneOntologyBiologicalProcesssynaptic vesicle membrane organization

RIMS1 STXBP1

8.66e-0436252GO:0048499
GeneOntologyBiologicalProcessresponse to wounding

NEO1 MIA3 STXBP1 PSG3 SYTL4

1.02e-03659255GO:0009611
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

NEO1 NTNG2 RIMS1 STXBP1 EIF4A3

1.05e-03663255GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

NEO1 NTNG2 RIMS1 STXBP1 EIF4A3

1.06e-03664255GO:0099177
GeneOntologyBiologicalProcessvesicle docking involved in exocytosis

RIMS1 STXBP1

1.29e-0344252GO:0006904
GeneOntologyBiologicalProcesspositive regulation of secretion by cell

MYO18A TMF1 STXBP1 SYTL4

1.32e-03404254GO:1903532
GeneOntologyBiologicalProcessacrosome reaction

RIMS1 STXBP1

1.47e-0347252GO:0007340
GeneOntologyCellularComponentpresynaptic active zone membrane

NTNG2 RIMS1 STXBP1

9.56e-0578243GO:0048787
GeneOntologyCellularComponentextrinsic component of presynaptic membrane

RIMS1 STXBP1

1.91e-0418242GO:0098888
GeneOntologyCellularComponentglutamatergic synapse

NEO1 NTNG2 RIMS1 STXBP1 SRGAP3 EIF4A3

2.57e-04817246GO:0098978
GeneOntologyCellularComponentpresynaptic active zone cytoplasmic component

RIMS1 STXBP1

3.15e-0423242GO:0098831
GeneOntologyCellularComponentsynaptic membrane

GPHN NEO1 NTNG2 RIMS1 STXBP1

4.54e-04583245GO:0097060
GeneOntologyCellularComponentextrinsic component of plasma membrane

GPHN RIMS1 STXBP1

5.04e-04137243GO:0019897
GeneOntologyCellularComponentpresynaptic active zone

NTNG2 RIMS1 STXBP1

5.48e-04141243GO:0048786
GeneOntologyCellularComponentinhibitory synapse

GPHN RIMS1

5.76e-0431242GO:0060077
GeneOntologyCellularComponentextrinsic component of synaptic membrane

RIMS1 STXBP1

7.34e-0435242GO:0099243
GeneOntologyCellularComponentserine/threonine protein kinase complex

ERCC3 RB1CC1 PSG3

7.49e-04157243GO:1902554
GeneOntologyCellularComponentpostsynapse

GPHN NEO1 RIMS1 STXBP1 SRGAP3 EIF4A3

8.30e-041018246GO:0098794
GeneOntologyCellularComponentprotein kinase complex

ERCC3 RB1CC1 PSG3

9.43e-04170243GO:1902911
GeneOntologyCellularComponentcell cortex region

RIMS1 STXBP1

1.21e-0345242GO:0099738
GeneOntologyCellularComponentextrinsic component of membrane

GPHN RIMS1 STXBP1

2.24e-03230243GO:0019898
GeneOntologyCellularComponentpresynaptic membrane

NTNG2 RIMS1 STXBP1

3.79e-03277243GO:0042734
GeneOntologyCellularComponentplatelet alpha granule

STXBP1 SYTL4

5.07e-0393242GO:0031091
DomainFYVE_2

RIMS1 SYTL4

9.39e-0511252PF02318
DomainRABBD

RIMS1 SYTL4

1.13e-0412252PS50916
DomainRab_BD

RIMS1 SYTL4

1.13e-0412252IPR010911
DomainPDZ

MYO18A RIMS1 DVL1P1

8.58e-04141253PF00595
DomainPDZ

MYO18A RIMS1 DVL1P1

9.87e-04148253SM00228
DomainPDZ

MYO18A RIMS1 DVL1P1

1.05e-03151253PS50106
DomainPDZ

MYO18A RIMS1 DVL1P1

1.07e-03152253IPR001478
DomainZnf_FYVE

RIMS1 SYTL4

1.17e-0338252IPR000306
DomainZF_FYVE

RIMS1 SYTL4

1.30e-0340252PS50178
DomainCH

NAV2 CAMSAP1

4.26e-0373252PS50021
DomainIg_2

NEO1 PSG3

4.26e-0373252PF13895
DomainCH-domain

NAV2 CAMSAP1

4.50e-0375252IPR001715
DomainHelicase_C

ERCC3 EIF4A3

8.95e-03107252PF00271
DomainHELICc

ERCC3 EIF4A3

8.95e-03107252SM00490
DomainHelicase_C

ERCC3 EIF4A3

9.11e-03108252IPR001650
DomainHELICASE_CTER

ERCC3 EIF4A3

9.28e-03109252PS51194
DomainHELICASE_ATP_BIND_1

ERCC3 EIF4A3

9.28e-03109252PS51192
DomainDEXDc

ERCC3 EIF4A3

9.28e-03109252SM00487
DomainHelicase_ATP-bd

ERCC3 EIF4A3

9.44e-03110252IPR014001
PathwayREACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE

RIMS1 STXBP1

2.84e-0417212M93
PathwayREACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE

RIMS1 STXBP1

2.84e-0417212MM14907
PathwayREACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE

RIMS1 STXBP1

3.19e-0418212M27043
PathwayREACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE

RIMS1 STXBP1

3.19e-0418212M13015
PathwayREACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE

RIMS1 STXBP1

3.19e-0418212MM14702
PathwayREACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE

RIMS1 STXBP1

3.19e-0418212MM14703
PathwayREACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION

RIMS1 STXBP1

3.56e-0419212M927
PathwayREACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION

RIMS1 STXBP1

3.56e-0419212MM15523
PathwayREACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE

RIMS1 STXBP1

5.25e-0423212MM14852
PathwayREACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE

RIMS1 STXBP1

5.25e-0423212M12627
PathwayREACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE

RIMS1 STXBP1

5.72e-0424212MM14834
PathwayREACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE

RIMS1 STXBP1

5.72e-0424212M630
PathwayWP_SPLICING_FACTOR_NOVA_REGULATED_SYNAPTIC_PROTEINS

GPHN NEO1

1.76e-0342212MM15822
PathwayWP_SPLICING_FACTOR_NOVA_REGULATED_SYNAPTIC_PROTEINS

GPHN NEO1

1.76e-0342212M39703
PathwayWP_SYNAPTIC_VESICLE_PATHWAY

RIMS1 STXBP1

2.58e-0351212M39457
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

RIMS1 STXBP1

2.58e-0351212MM14499
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

RIMS1 STXBP1

2.58e-0351212M4281
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

MYO18A GPHN NHSL1 NEO1 MIA3 RIMS1 STXBP1 CAMSAP1 SRGAP3 ARCN1

4.50e-091139261036417873
Pubmed

Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses.

GPHN RIMS1 STXBP1

1.07e-062726319723784
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

ACOT7 TMF1 NEO1 MIA3 SYTL4 EIF4A3 ARCN1

4.70e-0695226738569033
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

GPHN NAV2 NHSL1 RTL9

4.99e-0615326410718198
Pubmed

Munc18-1 regulates early and late stages of exocytosis via syntaxin-independent protein interactions.

STXBP1 SYTL4

5.37e-06526215563604
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MYO18A GPHN ACOT7 NHSL1 RIMS1 STXBP1 SRGAP3 ARCN1

6.48e-06143126837142655
Pubmed

STXBP1 promotes Weibel-Palade body exocytosis through its interaction with the Rab27A effector Slp4-a.

STXBP1 SYTL4

8.05e-06626224700782
Pubmed

The role of SNARE proteins in trafficking and function of neurotransmitter transporters.

RIMS1 STXBP1

1.13e-05726216722236
Pubmed

Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.

NEO1 RIMS1 STXBP1

1.23e-056026332027825
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

TMF1 WBP11 NEO1 MIA3 CAMSAP1 SYTL4

1.38e-0573326634672954
Pubmed

Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse.

GPHN RIMS1 STXBP1

1.72e-056726316987237
Pubmed

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.

MYO18A ACOT7 TMF1 WBP11 EIF4A3 ARCN1

2.04e-0578626629128334
Pubmed

Analysis of SUMO1-conjugation at synapses.

GPHN RIMS1

2.94e-051126228598330
Pubmed

Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.

MYO18A MIA3 RB1CC1

3.27e-05832639039502
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

GPHN TMF1 MIA3 CAMSAP1

3.49e-0525126429778605
Pubmed

A shared vesicular carrier allows synaptic corelease of GABA and glycine.

GPHN RIMS1

3.53e-051226216701208
Pubmed

Neogenin-loss in neural crest cells results in persistent hyperplastic primary vitreous formation.

NEO1 MITF

3.53e-051226231336386
Pubmed

SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle release.

RIMS1 STXBP1

3.53e-051226217803915
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

GPHN RIMS1 STXBP1 SRGAP3

5.42e-0528126428706196
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

GPHN WBP11 MIA3 RIMS1 CAMSAP1 SRGAP3

6.35e-0596326628671696
Pubmed

Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells.

STXBP1 SYTL4

6.41e-051626212590134
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

MYO18A RIMS1 STXBP1 SRGAP3

1.22e-0434726417114649
Pubmed

Intrinsically Disordered Protein TEX264 Mediates ER-phagy.

GPHN WBP11 RB1CC1

1.27e-0413126331006538
Pubmed

Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons.

NEO1 NTNG2

1.47e-042426226633881
Pubmed

Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.

RIMS1 STXBP1

1.73e-042626217124501
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

TMF1 NEO1 CAMSAP1 SYTL4 ARCN1

2.45e-0477726535844135
Pubmed

The synaptic vesicle cycle.

RIMS1 STXBP1

2.47e-043126215217342
Pubmed

Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex.

GPHN EIF4A3

3.15e-043526237758766
Pubmed

Axon guidance genes control hepatic artery development.

NEO1 PSG3

3.33e-043626237497580
Pubmed

The phagosomal proteome in interferon-gamma-activated macrophages.

MYO18A STXBP1

4.12e-044026219144319
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

NHSL1 MIA3 CAMSAP1

5.02e-0420926336779422
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

GPHN WBP11 SRGAP3 EIF4A3 ARCN1

5.20e-0491626532203420
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYO18A NAV2 WBP11 RIMS1 STXBP1 EIF4A3

5.66e-04144226635575683
Pubmed

FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates.

TMF1 RB1CC1 EIF4A3

6.06e-0422326334226595
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

NAV2 NTNG2 SRGAP3

6.22e-0422526312168954
Pubmed

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.

MYO18A MIA3 RB1CC1

6.63e-0423026335449600
CytobandEnsembl 112 genes in cytogenetic band chr6q13

RIMS1 KHDC1

6.47e-0466262chr6q13
CytobandEnsembl 112 genes in cytogenetic band chr9q34

NTNG2 STXBP1 CAMSAP1

8.10e-04325263chr9q34
GeneFamilyPDZ domain containing

MYO18A RIMS1

6.86e-031521521220
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

WBP11 RB1CC1

9.61e-03181152694
ToppCellfacs-Marrow-B-cells-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIMS1 SRGAP3 RTL9

7.75e-051432636df16bf0324661cd9707df69cb39f4b5498d6d49
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG2 CAMSAP1 KHDC1

8.41e-05147263ad0c575bc9c5f201f2a7810452e8b3f741e65d89
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG2 CAMSAP1 KHDC1

8.41e-05147263f5109e0f4e8b46a977a763c9c72a2df9840e3977
ToppCell3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3|bone_marrow / Manually curated celltypes from each tissue

NAV2 RASSF6 SRGAP3

8.75e-05149263d7f1069f70f3cad6d3700ee2041ed1d4cb7c49ab
ToppCellAdult-Epithelial-basal_cell-D122|Adult / Lineage, Cell type, age group and donor

RASSF6 SRGAP3 KHDC1

9.65e-0515426338d346402417960044ae999e61f0092b46f2b591
ToppCellControl-Endothelial-Epi-like-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RIMS1 EIF4A3 ARCN1

1.02e-041572632c369660c752c0fb3bd798a561d3359e2f9aa983
ToppCellControl-Endothelial-Epi-like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RIMS1 EIF4A3 ARCN1

1.02e-041572634d02c50d5d1b892ea241e98724386d8a5a156a46
ToppCellBasal_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

RASSF6 SRGAP3 KHDC1

1.08e-04160263b223cc47e68a29df4758c5ccf8f6dbffe2a6fa1d
ToppCell5'-Adult-SmallIntestine-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACOT7 SYTL4 RASSF6

1.20e-041662630b4e1d879c61be9d18d7aac51e5115f103f51209
ToppCellNS-critical-d_0-4-Epithelial-unknown_epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RIMS1 SYTL4 RASSF6

1.20e-04166263dd02bbe4af609c6348dc92417254f4740f2900a8
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIMS1 STXBP1 RASSF6

1.32e-0417126399176a932569fa1c7e1c01009684f5a65244b96e
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

RASSF6 SRGAP3 KHDC1

1.32e-041712633965ced4be6db14265a90673502fceee425837ca
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RASSF6 SRGAP3 KHDC1

1.46e-04177263cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RASSF6 SRGAP3 KHDC1

1.46e-04177263ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIMS1 STXBP1 RASSF6

1.53e-04180263f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO18A ERCC3 FMO5

1.61e-041832633ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIA3 STXBP1 RASSF6

1.69e-0418626332d30f08b20a0a28e38b37bd52ab26d1d43736ce
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMF1 WBP11 RB1CC1

1.82e-041912631ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCellfacs-Bladder-nan-3m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOT7 NHSL1 FMO5

1.91e-04194263e74cd8cf3763f6adbfd1c269a886a806049714cf
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAV2 ACOT7 RIMS1

1.91e-04194263bea369e9a7018d862e4d7f1c9ec2de50f3fd38ec
ToppCellIPF-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

NHSL1 SRGAP3 MITF

1.94e-04195263de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV2 MIA3 STXBP1

1.94e-041952633e519cffa6144a62b06124642a14c9ff39b76554
ToppCellASK440-Epithelial-Type_2|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

NHSL1 FMO5 STXBP1

1.97e-04196263754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCell3'-Child09-12-SmallIntestine-Epithelial-goblet|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIA3 SYTL4 RASSF6

1.97e-04196263c2d17630f7bfc9e727de55e093c17fddac61b61f
ToppCell3'-Child09-12-SmallIntestine-Epithelial-goblet-Goblet_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIA3 SYTL4 RASSF6

1.97e-0419626354c30023d04e7265373647f56fc93885804938b0
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

GPHN NAV2 NHSL1

2.03e-041982631996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Neuronal-CPNs|3_mon / Sample Type, Dataset, Time_group, and Cell type.

ACOT7 NHSL1 NEO1

2.03e-0419826360d8d3bbd754ffde41c50013d822667b185a9751
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NAV2 RIMS1 FMO5

2.06e-041992637223f853335492ca617dbec3e4b6872a8a463a45
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RIMS1 RASSF6 SRGAP3

2.06e-04199263f5c3561744e2a0e7716657cb521acb1d8f054b41
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal-Neurons|GW16 / Sample Type, Dataset, Time_group, and Cell type.

ACOT7 NHSL1 STXBP1

2.06e-04199263ae575ed7582f2a4218f6cbcbf5f7f0ce7a5bc26b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Cortical_neuron|GW10 / Sample Type, Dataset, Time_group, and Cell type.

ACOT7 NEO1 STXBP1

2.09e-04200263458fb0f40c1720f1cacedf78c40bd059692bfc62
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal|GW16 / Sample Type, Dataset, Time_group, and Cell type.

ACOT7 NHSL1 STXBP1

2.09e-042002631decf1d2cba5ebfd3e5cd4bcd637db8f193033ce
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial-Proteoglycan-expressing_cell|GW19 / Sample Type, Dataset, Time_group, and Cell type.

NAV2 SYTL4 MITF

2.09e-04200263aafe594c88710f8c53d59667cdac5035e08f5511
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

NAV2 SYTL4 MITF

2.09e-04200263a6f0f5f644b7262878b0b9d4d90ee407c4124dd9
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MIA3 RIMS1 SRGAP3

2.09e-04200263ed093626a9cac7531a2bf02f6e345c5e84b8c060
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Neuron|6m / Sample Type, Dataset, Time_group, and Cell type.

ACOT7 STXBP1 SRGAP3

2.09e-04200263b5019b9d48f32cffd4645a5c0f3e0ac504ea8019
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-CPNs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

ACOT7 NHSL1 STXBP1

2.09e-0420026371cbefbef4ae5bbb5f6e419914f4b3b3b5a5f9e3
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-cortical_neurons_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

NHSL1 NEO1 STXBP1

2.09e-042002630cb0755a101ec655359d051d6a8807408d727c55
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital|World / Primary Cells by Cluster

ACOT7 NHSL1 NEO1

2.09e-042002636bbe8e1f3e91678f1bfb14945365c1578a59a604
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital-19|World / Primary Cells by Cluster

ACOT7 NHSL1 NEO1

2.09e-04200263c831d9e0a7178e3634da45548f91fa9e8dc6557c
DiseaseNeurodevelopmental Disorders

RIMS1 STXBP1 SRGAP3

7.48e-0593263C1535926
Diseaseanti-GAD65 autoimmune neurological syndromes

NAV2 NEO1

4.36e-0435262EFO_0803379
DiseaseCutaneous Melanoma

ERCC3 MITF

5.99e-0441262C0151779
Diseasecholesteryl ester 20:4 measurement

NAV2 NHSL1

6.90e-0444262EFO_0010348
Diseasebrain measurement, neuroimaging measurement

NAV2 NHSL1 NEO1 MITF

1.29e-03550264EFO_0004346, EFO_0004464
Diseaseschizophrenia (implicated_via_orthology)

RIMS1 SRGAP3

1.64e-0368262DOID:5419 (implicated_via_orthology)
DiseaseManic Disorder

NTNG2 RIMS1

1.79e-0371262C0024713
DiseaseManic

NTNG2 RIMS1

2.15e-0378262C0338831
DiseaseDepression, Bipolar

NTNG2 RIMS1

2.21e-0379262C0005587
Diseasereaction time measurement

NAV2 NTNG2 RIMS1 SRGAP3

2.48e-03658264EFO_0008393
Diseasecortical thickness

NAV2 NHSL1 NEO1 SRGAP3 MITF

2.57e-031113265EFO_0004840
Diseasenevus count, cutaneous melanoma

MIA3 MITF

2.91e-0391262EFO_0000389, EFO_0004632
Diseasemitochondrial DNA measurement

FMO5 RB1CC1 SYTL4

2.93e-03328263EFO_0006312
Diseasenon-high density lipoprotein cholesterol measurement

PSG3 RASSF6 ARCN1 MITF

3.31e-03713264EFO_0005689
Diseasemyocardial infarction

MIA3 EIF4A3 MITF

3.51e-03350263EFO_0000612

Protein segments in the cluster

PeptideGeneStartEntry
TISGRMTFTSNKSME

ACOT7

291

O00154
SMASGSVKMTSFAER

CAMSAP1

806

Q5T5Y3
TSMKSSDVFSSKGMT

RASSF6

116

Q6ZTQ3
STGNQMSSRLMSMRS

GPHN

691

Q9NQX3
MSQSMSSVSSRHSEK

RB1CC1

1481

Q8TDY2
MATTATMATSGSARK

EIF4A3

1

P38919
GSRSDTSARMSAAEM

NHSL1

1431

Q5SYE7
RATSMRKTFTTGMAA

MYO18A

1001

Q92614
RRMGTSGRSIMKSTS

RIMS1

1386

Q86UR5
SGRSIMKSTSVSGEM

RIMS1

1391

Q86UR5
RSSSMTSTMTIGKFM

FMO5

506

P49326
RSKRSEQSMDMGTSA

KHDC1

66

Q4VXA5
RSSQASRRFGTMSSM

ERCC3

736

P19447
ADRASSFSSMTDSTM

DVL1P1

231

P54792
GETIMSSSMGKRTSE

ARCN1

246

P48444
SSSMGKRTSEATKMH

ARCN1

251

P48444
VRNSATGMESSKSMT

PSG3

396

Q16557
GMSARRARDMSSSSA

NTNG2

176

Q96CW9
ARSTSFMRASVSGSM

RTL9

1026

Q8NET4
RSSMQSGSSMSTIGS

SYTL4

326

Q96C24
SGTATMMNSSSRGSS

MIA3

1731

Q5JRA6
MVTKGRRSSTWSMTA

NEO1

931

Q92859
SMSLDEKSRTMSRSG

NAV2

1611

Q8IVL1
SSSKRMNTGEKTTMR

STXBP1

311

P61764
TMSRSSSISGVDMAG

TMF1

931

P82094
GASKTSSRRSSMSME

MITF

506

O75030
RRSSSSSTEMMTTFK

SRGAP3

1026

O43295
MGRRSTSSTKSGKFM

WBP11

1

Q9Y2W2