Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein serine kinase activity	STK35 CDC42BPB CDK10 ULK3 MAP3K10 TAOK1 PKN2 DCLK2 MAPK7 MAP3K21 DCLK1	7.45e-06	363	114	11	GO:0106310
GeneOntologyMolecularFunction	protein kinase activity	STK35 CDC42BPB CDK10 SCYL2 ULK3 MST1R BRD4 MAP3K10 TAOK1 PKN2 DCLK2 MAPK7 MAP3K21 DCLK1	8.29e-06	600	114	14	GO:0004672
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	STK35 CDC42BPB CDK10 ULK3 BRD4 MAP3K10 TAOK1 PKN2 DCLK2 MAPK7 MAP3K21 DCLK1	9.39e-06	446	114	12	GO:0004674
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	STK35 CDC42BPB CDK10 SCYL2 ULK3 MST1R BRD4 MAP3K10 TAOK1 PKN2 DCLK2 MAPK7 MAP3K21 DCLK1	5.24e-05	709	114	14	GO:0016773
GeneOntologyMolecularFunction	kinase activity	STK35 CDC42BPB CDK10 SCYL2 ULK3 MST1R BRD4 MAP3K10 TAOK1 PKN2 DCLK2 MAPK7 MAP3K21 DCLK1	1.16e-04	764	114	14	GO:0016301
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	STK35 CDC42BPB CDK10 POLR3A SCYL2 ULK3 MST1R BRD4 MAP3K10 TAOK1 PKN2 DCLK2 MAPK7 MAP3K21 DCLK1	2.88e-04	938	114	15	GO:0016772
GeneOntologyMolecularFunction	DNA translocase activity	RAD54B RAD54L	3.19e-04	5	114	2	GO:0015616
GeneOntologyMolecularFunction	piRNA binding	PIWIL2 MOV10L1	4.77e-04	6	114	2	GO:0034584
GeneOntologyBiologicalProcess	meiotic cell cycle process	NCAPD3 EME1 HUS1 PIWIL2 PSMD13 FANCD2 ZSCAN21 WASHC5 MOV10L1 RAD54B RAD54L	3.13e-07	268	115	11	GO:1903046
GeneOntologyBiologicalProcess	meiotic nuclear division	NCAPD3 EME1 PIWIL2 PSMD13 FANCD2 ZSCAN21 WASHC5 MOV10L1 RAD54B RAD54L	9.66e-07	240	115	10	GO:0140013
GeneOntologyBiologicalProcess	meiosis I	EME1 PIWIL2 PSMD13 FANCD2 ZSCAN21 MOV10L1 RAD54B RAD54L	1.71e-06	147	115	8	GO:0007127
GeneOntologyBiologicalProcess	meiosis I cell cycle process	EME1 PIWIL2 PSMD13 FANCD2 ZSCAN21 MOV10L1 RAD54B RAD54L	2.54e-06	155	115	8	GO:0061982
GeneOntologyBiologicalProcess	meiotic cell cycle	NCAPD3 EME1 HUS1 PIWIL2 PSMD13 FANCD2 ZSCAN21 WASHC5 MOV10L1 RAD54B RAD54L	4.24e-06	350	115	11	GO:0051321
GeneOntologyBiologicalProcess	nuclear division	NCAPD3 EME1 PIWIL2 PSMD13 FANCD2 ZSCAN21 WASHC5 MOV10L1 RAD54B MAD2L2 CDCA5 RAD54L	2.92e-05	512	115	12	GO:0000280
GeneOntologyBiologicalProcess	organelle fission	NCAPD3 EME1 PIWIL2 PSMD13 FANCD2 ZSCAN21 WASHC5 MOV10L1 RAD54B MAD2L2 CDCA5 RAD54L	8.34e-05	571	115	12	GO:0048285
GeneOntologyBiologicalProcess	peptidyl-amino acid modification	STOX1 CDC42BPB CDK10 TTLL7 ULK3 SENP1 TTLL2 TREM2 MAP3K10 PRMT9 PKN2 DCLK2 GALNT6 MAD2L2 MAPK7 DCLK1	1.03e-04	976	115	16	GO:0018193
GeneOntologyBiologicalProcess	mitotic intra-S DNA damage checkpoint signaling	EME1 HUS1 FANCD2	1.08e-04	17	115	3	GO:0031573
GeneOntologyBiologicalProcess	signal transduction in response to DNA damage	EME1 HUS1 FANCD2 PLA2R1 BRD4 TAOK1 MAD2L2	1.31e-04	200	115	7	GO:0042770
Domain	S_TKc	STK35 CDC42BPB CDK10 SCYL2 ULK3 MAP3K10 TAOK1 PKN2 DCLK2 MAPK7 MAP3K21 DCLK1	1.67e-06	359	112	12	SM00220
Domain	Protein_kinase_ATP_BS	STK35 CDC42BPB CDK10 ULK3 MST1R MAP3K10 TAOK1 PKN2 DCLK2 MAPK7 MAP3K21 DCLK1	2.92e-06	379	112	12	IPR017441
Domain	HEAT_REPEAT	PDS5B NCAPD3 PPP4R4 SCYL2 SF3B1 UTP20	3.90e-06	70	112	6	PS50077
Domain	ARM-like	PDS5B NCAPD3 RSPH14 IPO7 DOCK10 FRYL PPP4R4 SCYL2 SF3B1 UTP20	5.23e-06	270	112	10	IPR011989
Domain	ARM-type_fold	PDS5B NCAPD3 RSPH14 IPO7 DOCK11 FRYL PPP4R4 SCYL2 FOCAD SF3B1 UTP20	6.14e-06	339	112	11	IPR016024
Domain	Prot_kinase_dom	STK35 CDC42BPB CDK10 SCYL2 ULK3 MST1R MAP3K10 TAOK1 PKN2 DCLK2 MAPK7 MAP3K21 DCLK1	7.43e-06	489	112	13	IPR000719
Domain	-	PDS5B NCAPD3 RSPH14 IPO7 FRYL PPP4R4 SCYL2 SF3B1 UTP20	7.67e-06	222	112	9	1.25.10.10
Domain	PROTEIN_KINASE_DOM	STK35 CDC42BPB CDK10 SCYL2 ULK3 MST1R MAP3K10 TAOK1 PKN2 DCLK2 MAPK7 MAP3K21 DCLK1	8.11e-06	493	112	13	PS50011
Domain	Ser/Thr_kinase_AS	STK35 CDC42BPB CDK10 ULK3 MAP3K10 TAOK1 PKN2 DCLK2 MAPK7 MAP3K21 DCLK1	1.00e-05	357	112	11	IPR008271
Domain	PROTEIN_KINASE_ST	STK35 CDC42BPB CDK10 ULK3 MAP3K10 TAOK1 PKN2 DCLK2 MAPK7 MAP3K21 DCLK1	1.14e-05	362	112	11	PS00108
Domain	Pkinase	STK35 CDC42BPB CDK10 SCYL2 ULK3 MAP3K10 TAOK1 PKN2 DCLK2 MAPK7 DCLK1	1.83e-05	381	112	11	PF00069
Domain	PROTEIN_KINASE_ATP	STK35 CDC42BPB CDK10 ULK3 MST1R MAP3K10 TAOK1 PKN2 DCLK2 MAPK7 MAP3K21 DCLK1	2.01e-05	459	112	12	PS00107
Domain	Kinase-like_dom	STK35 CDC42BPB CDK10 SCYL2 ULK3 MST1R MAP3K10 TAOK1 PKN2 DCLK2 MAPK7 MAP3K21 DCLK1	2.21e-05	542	112	13	IPR011009
Domain	HEAT	NCAPD3 SCYL2 SF3B1 UTP20	1.95e-04	48	112	4	PF02985
Domain	Peptidase_S1C	HTRA1 HTRA3	2.12e-04	4	112	2	IPR001940
Domain	MLK1/MLK2/MLK4	MAP3K10 MAP3K21	2.12e-04	4	112	2	IPR016231
Domain	MAP3K10	MAP3K10 MAP3K21	2.12e-04	4	112	2	IPR015785
Domain	NUT	NUTM2G NUTM2F	3.52e-04	5	112	2	IPR024310
Domain	NUT_N	NUTM2G NUTM2F	3.52e-04	5	112	2	IPR024309
Domain	NUT	NUTM2G NUTM2F	3.52e-04	5	112	2	PF12881
Domain	HEAT	NCAPD3 SCYL2 SF3B1 UTP20	4.05e-04	58	112	4	IPR000357
Domain	DUF3398	DOCK11 DOCK10	5.26e-04	6	112	2	PF11878
Domain	DCX	DCLK2 DCLK1	5.26e-04	6	112	2	SM00537
Domain	DOCK_C/D_N	DOCK11 DOCK10	5.26e-04	6	112	2	IPR021816
Domain	-	DCLK2 DCLK1	7.34e-04	7	112	2	3.10.20.230
Domain	DCX	DCLK2 DCLK1	7.34e-04	7	112	2	PF03607
Domain	SNF2_N	RAD54B SHPRH RAD54L	9.17e-04	32	112	3	IPR000330
Domain	SNF2_N	RAD54B SHPRH RAD54L	9.17e-04	32	112	3	PF00176
Domain	DC	DCLK2 DCLK1	9.75e-04	8	112	2	PS50309
Domain	Doublecortin_dom	DCLK2 DCLK1	9.75e-04	8	112	2	IPR003533
Domain	DOCK_C	DOCK11 DOCK10	1.89e-03	11	112	2	IPR010703
Domain	DHR-1_domain	DOCK11 DOCK10	1.89e-03	11	112	2	IPR027007
Domain	DHR_2	DOCK11 DOCK10	1.89e-03	11	112	2	PS51651
Domain	DHR_1	DOCK11 DOCK10	1.89e-03	11	112	2	PS51650
Domain	DOCK-C2	DOCK11 DOCK10	1.89e-03	11	112	2	PF14429
Domain	DHR-2	DOCK11 DOCK10	1.89e-03	11	112	2	IPR027357
Domain	DHR-2	DOCK11 DOCK10	1.89e-03	11	112	2	PF06920
Domain	DOCK	DOCK11 DOCK10	1.89e-03	11	112	2	IPR026791
Domain	TTL	TTLL7 TTLL2	2.66e-03	13	112	2	PS51221
Domain	TTL/TTLL_fam	TTLL7 TTLL2	2.66e-03	13	112	2	IPR004344
Domain	TTL	TTLL7 TTLL2	2.66e-03	13	112	2	PF03133
Domain	SCAN	ZNF24 ZSCAN21 ZNF396	4.62e-03	56	112	3	SM00431
Domain	SCAN_BOX	ZNF24 ZSCAN21 ZNF396	5.10e-03	58	112	3	PS50804
Domain	SCAN	ZNF24 ZSCAN21 ZNF396	5.10e-03	58	112	3	PF02023
Domain	SCAN_dom	ZNF24 ZSCAN21 ZNF396	5.10e-03	58	112	3	IPR003309
Domain	IB	HTRA1 HTRA3	5.12e-03	18	112	2	SM00121
Domain	Retrov_capsid_C	ZNF24 ZSCAN21 ZNF396	5.35e-03	59	112	3	IPR008916
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	IPO7 HIP1R PSMD13 OLA1 PTBP1 SCYL2 FANCD2 SF3B1 NUP155 BRD4 TAOK1 PKN2 CNOT1	8.07e-08	582	116	13	20467437
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	PDS5B NCAPD3 ZSCAN12 IPO7 DAG1 PTBP1 EPM2AIP1 SENP1 ZNF24 GANAB SF3B1 NUP155 WASHC5 RRN3 BRD4 MTX1 MGA CNOT1	1.01e-07	1203	116	18	29180619
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	IPO7 POLR3A FANCD2 SF3B1 WASHC5 PKN2 MGA CDCA5	6.71e-07	215	116	8	35973513
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	PDS5B DCHS2 DOCK11 PSMD13 TMEM87A SNX14 SHPRH CSTF2 TAOK1 CNOT1 ARHGAP21	9.27e-07	497	116	11	36774506
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PDS5B FRMPD4 SYNE1 DOCK10 MFAP3L EPM2AIP1 FOCAD GANAB ARHGAP21 VPS13B	1.17e-06	407	116	10	12693553
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	FRMPD4 HIP1R DAG1 PSMD13 CORO1B NDUFA6 PTBP1 AQP4 CDC42BPB SF3B1 WASHC5 MAP3K10 DCLK2 MTX1 CNOT1 DCLK1	1.27e-06	1139	116	16	36417873
Pubmed	TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.	SCYL2 SEC24D SF3B1 NUP155	2.26e-06	28	116	4	29653964
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	NCAPD3 EME1 HUS1 PSMD13 FAAP100 EPM2AIP1 FANCD2 SF3B1 MAD2L2 MGA	3.04e-06	453	116	10	29656893
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	NCAPD3 IPO7 FRYL PTBP1 CDC42BPB UTP20 CNOT1	5.49e-06	202	116	7	33005030
Pubmed	Host PDZ-containing proteins targeted by SARS-CoV-2.	HTRA1 FRMPD4 HTRA3 ARHGAP21	5.68e-06	35	116	4	33864728
Pubmed	KDM3A promotes oral squamous cell carcinoma cell proliferation and invasion via H3K9me2 demethylation-activated DCLK1.	KDM3A DCLK1	1.10e-05	2	116	2	36094735
Pubmed	Ginkgolic acid improves bleomycin-induced pulmonary fibrosis by inhibiting SMAD4 SUMOylation.	SFTPC SENP1	1.10e-05	2	116	2	35707278
Pubmed	Doublecortin-like kinase enhances dendritic remodelling and negatively regulates synapse maturation.	DCLK2 DCLK1	1.10e-05	2	116	2	23385585
Pubmed	Serine proteases HTRA1 and HTRA3 are down-regulated with increasing grades of human endometrial cancer.	HTRA1 HTRA3	1.10e-05	2	116	2	16650464
Pubmed	m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis.	ALKBH5 SF3B1	1.10e-05	2	116	2	36944332
Pubmed	Structural and functional analysis of the PDZ domains of human HtrA1 and HtrA3.	HTRA1 HTRA3	1.10e-05	2	116	2	17962403
Pubmed	The Histone Demethylase KDM3A, Increased in Human Pancreatic Tumors, Regulates Expression of DCLK1 and Promotes Tumorigenesis in Mice.	KDM3A DCLK1	1.10e-05	2	116	2	31442435
Pubmed	Distribution of the serine protease HtrA1 in normal human tissues.	HTRA1 HTRA3	1.10e-05	2	116	2	14500695
Pubmed	Homology-driven chromatin remodeling by human RAD54.	RAD54B RAD54L	1.10e-05	2	116	2	17417655
Pubmed	Involvement of Zizimin2/3 in the age-related defect of peritoneal B-1a cells as a source of anti-bacterial IgM.	DOCK11 DOCK10	1.10e-05	2	116	2	29099971
Pubmed	Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell Identity.	BRD4 MAPK7	1.10e-05	2	116	2	27498864
Pubmed	Genetic probing of homologous recombination and non-homologous end joining during meiotic prophase in irradiated mouse spermatocytes.	RAD54B RAD54L	1.10e-05	2	116	2	20167225
Pubmed	The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation.	DOCK11 DOCK10	1.10e-05	2	116	2	25729399
Pubmed	Functional Similarities between the Protein O-Mannosyltransferases Pmt4 from Bakers' Yeast and Human POMT1.	DAG1 POMT1	1.10e-05	2	116	2	27358400
Pubmed	Regulation of the circadian rhythmic expression of Sglt1 in the mouse small intestine through histone acetylation and the mRNA elongation factor, BRD4-P-TEFb.	SLC5A1 BRD4	1.10e-05	2	116	2	29557282
Pubmed	Somatic hypermutation does not require Rad54 and Rad54B-mediated homologous recombination.	RAD54B RAD54L	1.10e-05	2	116	2	12548566
Pubmed	DNA double-strand break repair in parental chromatin of mouse zygotes, the first cell cycle as an origin of de novo mutation.	RAD54B RAD54L	1.10e-05	2	116	2	18353795
Pubmed	Identification and cloning of two isoforms of human high-temperature requirement factor A3 (HtrA3), characterization of its genomic structure and comparison of its tissue distribution with HtrA1 and HtrA2.	HTRA1 HTRA3	1.10e-05	2	116	2	12513693
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	PDS5B NCAPD3 TBC1D9B IPO7 HECTD3 DAG1 NDUFA6 FANCD2 GANAB NUP155 CSTF2 UTP20 MTX1	1.64e-05	942	116	13	31073040
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ZSCAN12 DOCK11 SYNE1 GRIK3 CORO1B CDC42BPB EPM2AIP1 SENP1 SF3B1 MGA CNOT1 ARHGAP21 DCLK1	2.06e-05	963	116	13	28671696
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	KDM3A SYNE1 EPM2AIP1 SEC24D NUP155	2.32e-05	101	116	5	9872452
Pubmed	RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.	RAD54B RAD54L	3.30e-05	3	116	2	25765654
Pubmed	STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis.	CDK10 PKN2	3.30e-05	3	116	2	27104747
Pubmed	Roles of the DOCK-D family proteins in a mouse model of neuroinflammation.	DOCK11 DOCK10	3.30e-05	3	116	2	32241915
Pubmed	Fanconi anemia FANCD2 and FANCI proteins regulate the nuclear dynamics of splicing factors.	FANCD2 SF3B1	3.30e-05	3	116	2	29030393
Pubmed	Mutations in the MOV10L1 ATP Hydrolysis Motif Cause piRNA Biogenesis Failure and Male Sterility in Mice.	PIWIL2 MOV10L1	3.30e-05	3	116	2	27655786
Pubmed	Rad54/Rad54B deficiency is associated to increased chromosome breakage in mouse spermatocytes.	RAD54B RAD54L	3.30e-05	3	116	2	30204892
Pubmed	Changes in mRNA and protein levels of human HtrA1, HtrA2 and HtrA3 in ovarian cancer.	HTRA1 HTRA3	3.30e-05	3	116	2	18241672
Pubmed	The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks.	EME1 RAD54L	3.30e-05	3	116	2	17036055
Pubmed	Drastic reduction of sarcalumenin in Dp427 (dystrophin of 427 kDa)-deficient fibres indicates that abnormal calcium handling plays a key role in muscular dystrophy.	DAG1 SRL	3.30e-05	3	116	2	14678011
Pubmed	Doublecortin-Like Kinases Promote Neuronal Survival and Induce Growth Cone Reformation via Distinct Mechanisms.	DCLK2 DCLK1	3.30e-05	3	116	2	26526391
Pubmed	HtrA proteins as targets in therapy of cancer and other diseases.	HTRA1 HTRA3	3.30e-05	3	116	2	20469960
Pubmed	Functional antagonism between high temperature requirement protein A (HtrA) family members regulates trophoblast invasion.	HTRA1 HTRA3	3.30e-05	3	116	2	25002585
Pubmed	RBM33 is a unique m6A RNA-binding protein that regulates ALKBH5 demethylase activity and substrate selectivity.	ALKBH5 SENP1	3.30e-05	3	116	2	37257451
Pubmed	OLA1, a Translational Regulator of p21, Maintains Optimal Cell Proliferation Necessary for Developmental Progression.	SFTPC OLA1	3.30e-05	3	116	2	27481995
Pubmed	Dynamics of expression patterns of AQP4, dystroglycan, agrin and matrix metalloproteinases in human glioblastoma.	DAG1 AQP4	3.30e-05	3	116	2	22307776
Pubmed	Analysis of the relationships between ATM and the Rad54 paralogs involved in homologous recombination repair.	RAD54B RAD54L	3.30e-05	3	116	2	19061978
Pubmed	The bromodomain protein Brd4 insulates chromatin from DNA damage signalling.	NCAPD3 BRD4	3.30e-05	3	116	2	23728299
Pubmed	DCLK1 is correlated with MET and ERK5 expression, and associated with prognosis in malignant pleural mesothelioma.	MAPK7 DCLK1	3.30e-05	3	116	2	28560410
Pubmed	POMT1 is essential for protein O-mannosylation in mammals.	DAG1 POMT1	3.30e-05	3	116	2	20816174
Pubmed	Changes in expression of human serine protease HtrA1, HtrA2 and HtrA3 genes in benign and malignant thyroid tumors.	HTRA1 HTRA3	3.30e-05	3	116	2	22923201
Pubmed	Expression of HTRA Genes and Its Association with Microsatellite Instability and Survival of Patients with Colorectal Cancer.	HTRA1 HTRA3	3.30e-05	3	116	2	32486357
Pubmed	Alternative transcripts of Dclk1 and Dclk2 and their expression in doublecortin knockout mice.	DCLK2 DCLK1	3.30e-05	3	116	2	18075264
Pubmed	A human MAP kinase interactome.	SYNE1 CCDC92 CDC42BPB SF3B1 SIMC1 MAP3K10 MAPK7 MAP3K21 MGA	3.84e-05	486	116	9	20936779
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	PDS5B IPO7 SYNE1 OLA1 PTBP1 ZNF24 GANAB SF3B1 NUP155 CSTF2 UTP20 MGA CNOT1	3.88e-05	1024	116	13	24711643
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PDS5B IPO7 HIP1R DOCK10 PSMD13 CORO1B PTBP1 POLR3A SF3B1 NUP155 WASHC5 UTP20 PKN2 MGA SORD	4.54e-05	1353	116	15	29467282
Pubmed	Fanconi Anemia	FAAP100 FANCD2 MAD2L2	6.10e-05	23	116	3	20301575
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	ZNF24 ZSCAN21 SIMC1 MAD2L2 MGA	6.45e-05	125	116	5	32891193
Pubmed	Peptide selectivity between the PDZ domains of human pregnancy-related serine proteases (HtrA1, HtrA2, HtrA3, and HtrA4) can be reshaped by different halogen probes.	HTRA1 HTRA3	6.59e-05	4	116	2	29266444
Pubmed	Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5' flap DNA: basis of interstrand cross-link repair by FAN1.	EME1 FANCD2	6.59e-05	4	116	2	25319828
Pubmed	A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging.	HTRA1 HTRA3	6.59e-05	4	116	2	27500671
Pubmed	Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein.	DAG1 AQP4	6.59e-05	4	116	2	11717465
Pubmed	Onset of aquaporin-4 expression in the developing mouse brain.	DAG1 AQP4	6.59e-05	4	116	2	24915007
Pubmed	Mitochondrial membrane-based initial separation of MIWI and MILI functions during pachytene piRNA biogenesis.	PIWIL2 MOV10L1	6.59e-05	4	116	2	30590800
Pubmed	The X-linked intellectual disability gene product and E3 ubiquitin ligase KLHL15 degrades doublecortin proteins to constrain neuronal dendritogenesis.	DCLK2 DCLK1	6.59e-05	4	116	2	33199366
Pubmed	Expression of the murine Pomt1 gene in both the developing brain and adult muscle tissues and its relationship with clinical aspects of Walker-Warburg syndrome.	DAG1 POMT1	6.59e-05	4	116	2	17456771
Pubmed	Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosis.	RAD54B RAD54L	6.59e-05	4	116	2	16428451
Pubmed	Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway.	PIWIL2 MOV10L1	6.59e-05	4	116	2	20534472
Pubmed	Identification and characterization of two novel human SCAN domain-containing zinc finger genes ZNF396 and ZNF397.	ZNF24 ZNF396	6.59e-05	4	116	2	12801647
Pubmed	Expression of human HtrA1, HtrA2, HtrA3 and TGF-beta1 genes in primary endometrial cancer.	HTRA1 HTRA3	6.59e-05	4	116	2	19424634
Pubmed	The role of the LB structural loop and its interactions with the PDZ domain of the human HtrA3 protease.	HTRA1 HTRA3	6.59e-05	4	116	2	28642151
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	NCAPD3 HECTD3 DOCK10 POLR3A FREM2 NUP155 WASHC5 RAD54B GALNT6 ARHGAP21	6.70e-05	650	116	10	38777146
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PDS5B KDM3A NCAPD3 IPO7 OLA1 PTBP1 ALKBH5 ZNF24 ZSCAN21 BRD4 CDCA5 CNOT1 SORD	8.23e-05	1103	116	13	34189442
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TBC1D9B HIP1R FRYL CORO1B FAAP100 CDC42BPB FOCAD HIVEP3 MST1R ADAMTS7 BRD4 ARHGAP21 CYB5R2	8.38e-05	1105	116	13	35748872
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	HTRA1 SYNE1 CORO1B NDUFA6 OLA1 PTBP1 AQP4 CDC42BPB SF3B1 WASHC5 NTM DCLK2 CNOT1 ARHGAP21 DCLK1	8.50e-05	1431	116	15	37142655
Pubmed	Gamma-radiation sensitivity and polymorphisms in RAD51L1 modulate glioma risk.	EME1 RAD54B RAD54L	9.97e-05	27	116	3	20610542
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	IPO7 HECTD3 FRYL PSMD13 CORO1B OLA1 PTBP1 FANCD2 SEC24D GANAB NUP155 WASHC5 CSTF2 CNOT1 SORD	1.02e-04	1455	116	15	22863883
Pubmed	Post-translational modification of RNA m6A demethylase ALKBH5 regulates ROS-induced DNA damage response.	ALKBH5 SENP1	1.10e-04	5	116	2	34048572
Pubmed	Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.	DOCK11 DOCK10	1.10e-04	5	116	2	15710388
Pubmed	Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethality.	DAG1 POMT1	1.10e-04	5	116	2	15383666
Pubmed	Abnormal development of placenta in HtrA1-deficient mice.	HTRA1 HTRA3	1.10e-04	5	116	2	25446274
Pubmed	Probing nuclear pore complex architecture with proximity-dependent biotinylation.	SYNE1 HIVEP3 SENP1 NUP155	1.32e-04	77	116	4	24927568
Pubmed	SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.	PDS5B NCAPD3 FANCD2 ZNF24 MAD2L2	1.52e-04	150	116	5	30154076
Pubmed	An evolutionarily conserved nested gene pair - Mab21 and Lrba/Nbea in metazoan.	DCLK2 DCLK1	1.64e-04	6	116	2	19482073
Pubmed	The RhoGEF DOCK10 is essential for dendritic spine morphogenesis.	DOCK11 DOCK10	1.64e-04	6	116	2	25851601
Pubmed	Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates.	PDS5B CDCA5	1.64e-04	6	116	2	15837422
Pubmed	Molecular identification and characterization of a family of kinases with homology to Ca2+/calmodulin-dependent protein kinases I/IV.	DCLK2 DCLK1	1.64e-04	6	116	2	16684769
Pubmed	A role for Fkbp6 and the chaperone machinery in piRNA amplification and transposon silencing.	PIWIL2 MOV10L1	1.64e-04	6	116	2	22902560
Pubmed	Expression of dystroglycan, fukutin and POMGnT1 during mouse cerebellar development.	DAG1 POMT1	1.64e-04	6	116	2	12670716
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	PDC DOCK11 PIWIL2 STOX1 DSCAML1 FOCAD FREM2 CSTF2 UTP20 CNOT1	1.84e-04	736	116	10	29676528
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	EME1 IPO7 PTBP1 SF3B1 NUP155 CSTF2 MGA	2.03e-04	357	116	7	37059091
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	PDS5B KDM3A IPO7 ZNF24 ZSCAN21 BRD4 RAD54B SHPRH MGA	2.09e-04	608	116	9	36089195
Pubmed	Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.	NCAPD3 EME1 FANCD2 CDCA5	2.11e-04	87	116	4	33798452
Pubmed	Epidemiology of the antibiotic resistance of Helicobacter pylori in Canada.	PDS5B CDCA5	2.29e-04	7	116	2	11111111
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	DOCK11 PLEKHG7 DOCK10 PSMD13 ZNF24 GANAB CSTF2 ARHGAP8 MGA CDCA5 ARHGAP21	2.54e-04	916	116	11	32203420
Pubmed	Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.	PTBP1 DCLK2 ARHGAP21	2.59e-04	37	116	3	27565344
Pubmed	USP1 deubiquitinates Akt to inhibit PI3K-Akt-FoxO signaling in muscle during prolonged starvation.	OTUD6A PSMD13 AQP4	2.59e-04	37	116	3	32133736
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	IPO7 PSMD13 PTBP1 GANAB SF3B1 NUP155 MAP3K21 CNOT1	2.61e-04	494	116	8	26831064
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PDS5B KDM3A NCAPD3 EME1 FANCD2 SF3B1 BRD4 UTP20 TAOK1 PKN2	2.75e-04	774	116	10	15302935
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	PDS5B NCAPD3 IPO7 SYNE1 PSMD13 OLA1 PTBP1 POLR3A FANCD2 GANAB SF3B1 NUP155 UTP20 CNOT1	2.89e-04	1425	116	14	30948266
Interaction	C19orf38 interactions	PDS5B NCAPD3 TBC1D9B HIP1R FANCD2 PRMT9 MAD2L2	5.72e-07	86	114	7	int:C19orf38
Interaction	BRCA1 interactions	NCAPD3 EME1 IPO7 HUS1 HECTD3 DAG1 PSMD13 OLA1 PTBP1 FAAP100 EPM2AIP1 FANCD2 GANAB SF3B1 NUP155 ZSCAN21 FAM161A BRD4 CSTF2 MAP3K21 CNOT1 ARHGAP21	1.67e-06	1249	114	22	int:BRCA1
Interaction	BTNL9 interactions	NCAPD3 TBC1D9B IPO7 SMIM3 FANCD2 FOCAD PRMT9 MAD2L2	2.96e-06	156	114	8	int:BTNL9
Interaction	CDC42 interactions	PDS5B NCAPD3 DOCK11 SYNE1 DOCK10 DAG1 FRYL OLA1 CDC42BPB TMEM87A FANCD2 SENP1 GANAB NUP155 BRD4 MAP3K10 UTP20 TAOK1 PKN2 ARHGAP8 CNOT1 ARHGAP21	4.27e-06	1323	114	22	int:CDC42
Interaction	SCN2B interactions	PDS5B HUS1 HIP1R FOCAD UTP20 CNOT1	1.66e-05	95	114	6	int:SCN2B
Interaction	SMC1A interactions	PDS5B HIP1R FANCD2 MST1R GANAB SF3B1 BRD4 CSTF2 MAD2L2 MGA CDCA5	2.54e-05	418	114	11	int:SMC1A
Interaction	RHOF interactions	PDS5B NCAPD3 IPO7 DOCK11 HIP1R DAG1 CDC42BPB SENP1 NUP155 UTP20 PKN2 MAD2L2 ARHGAP21 VPS13B	2.69e-05	673	114	14	int:RHOF
Interaction	NPTN interactions	PDS5B TMEM87A FANCD2 FOCAD GANAB RRN3 SIMC1 UTP20 MAD2L2	2.91e-05	278	114	9	int:NPTN
Interaction	STAG2 interactions	PDS5B HIP1R FANCD2 SF3B1 BRD4 MAD2L2 MGA CDCA5	4.12e-05	224	114	8	int:STAG2
Interaction	CD70 interactions	PDS5B HUS1 HIP1R DAG1 FANCD2 WASHC5 UTP20	4.45e-05	166	114	7	int:CD70
Interaction	GPR182 interactions	PDS5B NCAPD3 HIP1R TMEM87A FANCD2 FOCAD SNX14 WASHC5 SIMC1 UTP20 MTX1	5.49e-05	455	114	11	int:GPR182
Interaction	CDC37 interactions	HECTD3 PSMD13 STK35 CDK10 FANCD2 ULK3 MST1R BRD4 MAP3K10 DCLK2 MAPK7 MAP3K21 CDCA5	7.33e-05	645	114	13	int:CDC37
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	MAP3K10 TAOK1 MAP3K21	1.06e-04	24	70	3	654
GeneFamily	Doublecortin superfamily	DCLK2 DCLK1	6.52e-04	10	70	2	1369
GeneFamily	Tubulin tyrosine ligase family	TTLL7 TTLL2	1.30e-03	14	70	2	779
GeneFamily	PDZ domain containing	HTRA1 FRMPD4 HTRA3 ARHGAP21	2.86e-03	152	70	4	1220
ToppCell	ASK440-Epithelial-Transformed_epithelium\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	AQP4 PPP4R4 MFAP3L ZNF24 SLC10A5 SHPRH	5.99e-06	172	116	6	df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCell	AT1_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	AQP4 TTLL7 SLC5A1 PLA2R1 NTM DCLK1	7.53e-06	179	116	6	1603117b52623663458a977c94bf7f9f6c1114b8
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NCAPD3 EME1 FANCD2 RAD54B CDCA5 RAD54L	7.53e-06	179	116	6	80112c686a8f85ad5e3cda6e3f3d3d51cf688092
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NCAPD3 EME1 FANCD2 RAD54B CDCA5 RAD54L	7.77e-06	180	116	6	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NCAPD3 EME1 FANCD2 RAD54B CDCA5 RAD54L	7.77e-06	180	116	6	f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	RSPH14 PLEKHG7 UROC1 STOX1 DSCAML1 CFAP46	9.09e-06	185	116	6	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	DAG1 FRYL GANAB TAOK1 MGA VPS13B	1.16e-05	193	116	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	facs-Trachea-3m\|Trachea / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DAG1 PTBP1 ALKBH5 SEC24D SF3B1 TAOK1	1.30e-05	197	116	6	e77016d64b1cac9825fec7cfe5071f1567401187
ToppCell	facs-Trachea-nan-3m\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAG1 PTBP1 ALKBH5 SEC24D SF3B1 TAOK1	1.30e-05	197	116	6	0353d925ee4b7aefc2c51b5fab873f465cdf9ebc
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PLEKHG7 STOX1 SLC5A1 PLA2R1 GALNT6 SORD	1.34e-05	198	116	6	af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DCHS2 HTRA1 SYNE1 STOX1 AQP4 PPP4R4	1.41e-05	200	116	6	07d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DCHS2 HTRA1 SYNE1 STOX1 AQP4 PPP4R4	1.41e-05	200	116	6	d0812817ef99608994193787a62d39adeb2070ca
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DCHS2 HTRA1 SYNE1 STOX1 AQP4 PPP4R4	1.41e-05	200	116	6	cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_D\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ZSCAN12 PIWIL2 CDK10 SRL CFAP46	1.91e-05	125	116	5	9e98dcfdc768ae492f453efc08926164bbb0a909
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 FREM2 OTOGL MOV10L1 PDILT	3.90e-05	145	116	5	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	Healthy_donor-B_cell\|World / disease group, cell group and cell class (v2)	EME1 DSCAML1 RAD54B MAP3K21 CYB5R2	4.59e-05	150	116	5	a2dfed562de7f58f902b547acec5a13853c80c4c
ToppCell	NS-moderate-d_0-4-Myeloid-Monocyte-derived_DC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DOCK11 DOCK10 ADAMDEC1 TREM2 CDCA5	4.89e-05	152	116	5	ce944f7c1444fd0cb793db183b96818e37342b24
ToppCell	Healthy_donor-B_cell\|Healthy_donor / disease group, cell group and cell class (v2)	EME1 DSCAML1 RAD54B MAP3K21 CYB5R2	4.89e-05	152	116	5	5768edfde8010324d8594815e73bbfba2c3045f3
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_C\|TCGA-Thymus / Sample_Type by Project: Shred V9	PDC PLEKHG7 DSCAML1 MAP3K21 RAPGEFL1	6.81e-05	163	116	5	2dac87d15051151ccf193760ddd8b82534c3f922
ToppCell	343B-Epithelial_cells-Epithelial-A_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	SFTPC AQP4 TMEM87A OTOGL MALL	7.01e-05	164	116	5	beaa13a75c3bb72446c85084d75e9fe3f15fd3d4
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EME1 SLC5A1 MAPK7 CDCA5 DCLK1	7.01e-05	164	116	5	4ef776d1bab4103d42d3a4f22cdfb49e8d2bc5a0
ToppCell	343B-Epithelial_cells-Epithelial-A_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	SFTPC AQP4 TMEM87A OTOGL MALL	7.01e-05	164	116	5	d005cfd821b87548b075120bffe65a0be9860463
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EME1 FANCD2 RAD54B CDCA5 RAD54L	8.07e-05	169	116	5	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EME1 TTLL7 FANCD2 RAD54B RAD54L	8.07e-05	169	116	5	121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTRA1 IPO7 HTRA3 PKN2 ARHGAP21	9.77e-05	176	116	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	AT1_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	AQP4 TTLL7 SLC5A1 NTM DCLK1	9.77e-05	176	116	5	458720776b0151cd55acc352d509599cb62f0ca8
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	POLR3A SENP1 MALL RRN3 MAP3K21	1.00e-04	177	116	5	164ffbbf798defa3728197deb1a14b661490e525
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AQP4 DSCAML1 SLC5A1 ADAMDEC1 RAPGEFL1	1.03e-04	178	116	5	b89c4d015b44bf538aa39969ef8778877c8023f1
ToppCell	343B-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NCAPD3 DAG1 STOX1 RAD54B CDCA5	1.03e-04	178	116	5	c7e890cd02206c516cf1d7692ea7abc8ce746482
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AQP4 DSCAML1 SLC5A1 ADAMDEC1 RAPGEFL1	1.03e-04	178	116	5	fb8f8d95f6b08378fb42c4076ee040276faa296f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 DOCK11 SYNE1 EFCAB13 NTM	1.11e-04	181	116	5	5f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 DOCK11 SYNE1 EFCAB13 NTM	1.11e-04	181	116	5	c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell	343B-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	NCAPD3 DAG1 STOX1 RAD54B CDCA5	1.14e-04	182	116	5	b1e66ccd5f33b4801f1cafddf97f5fc0c6dba8d1
ToppCell	BAL-Control-Myeloid-Macrophage\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SMIM3 HAGHL ADAMDEC1 TREM2 DCLK1	1.17e-04	183	116	5	8e9d45c96b44558158e3d59613f64a73d5390c19
ToppCell	BAL-Control-Myeloid-Macrophage-transitional_Macro-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SMIM3 HAGHL ADAMDEC1 TREM2 DCLK1	1.17e-04	183	116	5	0408d991ddb639594b45d5cb2432dd29289167b1
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5\|TCGA-Liver / Sample_Type by Project: Shred V9	EME1 FANCD2 RAD54B CSTF2 RAD54L	1.17e-04	183	116	5	f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell	COPD-Epithelial-ATII\|World / Disease state, Lineage and Cell class	SFTPC SYNE1 AQP4 FREM2 MALL	1.17e-04	183	116	5	8e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell	BAL-Control-Myeloid-Macrophage-transitional_Macro\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SMIM3 HAGHL ADAMDEC1 TREM2 DCLK1	1.17e-04	183	116	5	79f05b8a967124d831b0baef137e30659f5917a7
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 GRIK3 DSCAML1 FREM2 OTOGL	1.20e-04	184	116	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	BAL-Control-Myeloid-Macrophage-transitional_Macro-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SMIM3 HAGHL ADAMDEC1 TREM2 DCLK1	1.20e-04	184	116	5	92202e1cd0bba1ce4b061ebcb8a2af5bb590542a
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 GRIK3 DSCAML1 FREM2 OTOGL	1.20e-04	184	116	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	TBC1D9B CCDC92 MFAP3L FANCD2 MGA	1.20e-04	184	116	5	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 GRIK3 DSCAML1 FREM2 OTOGL	1.20e-04	184	116	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	BAL-Control-Myeloid-Macrophage\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SMIM3 HAGHL ADAMDEC1 TREM2 DCLK1	1.20e-04	184	116	5	7331535d469453a5264dcb0270a97f63d3b55201
ToppCell	BAL-Control-Myeloid-Macrophage-transitional_Macro\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SMIM3 HAGHL ADAMDEC1 TREM2 DCLK1	1.20e-04	184	116	5	337e38a6b2b6770cc992d88b006829f194841b10
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Undifferentiated_Pleomorphic_Sarcoma\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	HECTD3 HTRA3 TREM2 MAD2L2 MTX1	1.33e-04	188	116	5	3df5a5b645403914c4d0506e2d93f8a8a98e3fa6
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D231\|Adult / Lineage, Cell type, age group and donor	AQP4 TTLL7 PLA2R1 NTM DCLK1	1.36e-04	189	116	5	5a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell	Control-Myeloid-transitional_Macro\|Control / Disease group,lineage and cell class （2021.01.30）	SMIM3 HAGHL ADAMDEC1 TREM2 DCLK1	1.43e-04	191	116	5	3ed0b1ff628a165e3c92c2e493206015f57dccfe
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SFTPC CCDC92 FREM2 MALL MAP3K21	1.43e-04	191	116	5	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	Control-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	SFTPC SYNE1 AQP4 FREM2 MALL	1.47e-04	192	116	5	1bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SFTPC SYNE1 PPP4R4 FREM2 MALL	1.50e-04	193	116	5	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFTPC SYNE1 AQP4 FREM2 CFAP46	1.50e-04	193	116	5	bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SFTPC SYNE1 PPP4R4 FREM2 MALL	1.50e-04	193	116	5	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	NS-critical-d_07-13-Epithelial-Secretory\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PLA2R1 FREM2 SLC10A5 RAPGEFL1 SORD	1.54e-04	194	116	5	2172d951896265243d14996eacce5aab5e14e26e
ToppCell	wk_20-22-Epithelial-Distal_epithelial-type_II_pneumocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SFTPC AQP4 FREM2 MALL MAP3K21	1.58e-04	195	116	5	45d1acd316d0ced97dfb150c3a943128d8fa4e7e
ToppCell	wk_15-18-Epithelial-Distal_epithelial-type_II_pneumocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SFTPC AQP4 FREM2 MALL MAP3K21	1.58e-04	195	116	5	0e3aac1b1a1fd483f5fb9a394eb90c0e1ce63542
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFTPC SYNE1 AQP4 FREM2 MALL	1.62e-04	196	116	5	7e5addaa844e66f8160e05858c341866a80aed23
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTRA1 HTRA3 AQP4 SEC24D DCLK1	1.62e-04	196	116	5	2029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IPO7 DAG1 PTBP1 SF3B1 TAOK1	1.62e-04	196	116	5	151f1a29a91f8b234e9b6ed062666357a2f69128
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 HTRA1 SYNE1 PLA2R1 NTM	1.62e-04	196	116	5	545d2e4469924d333e3f655f559c899fa1260196
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_3\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	PLEKHG7 EFCAB13 AQP4 ULK3 PLA2R1	1.66e-04	197	116	5	4f8f23b1ef2eae9d300bd2c1a5cb7ef0163858a1
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Basal_3\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	PLEKHG7 EFCAB13 AQP4 ULK3 PLA2R1	1.66e-04	197	116	5	2cff37f9d33951840a8f52ccbba6ca1a4bbe3ad9
ToppCell	Mild-Lymphoid-T-Proliferating_T\|Mild / Condition, Lineage, Cell class and cell subclass	NCAPD3 FANCD2 RAD54B CDCA5 RAD54L	1.66e-04	197	116	5	794517c70089da109f4c6489fe406c0ba6882b76
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFTPC SYNE1 AQP4 FREM2 MALL	1.66e-04	197	116	5	bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_3-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLEKHG7 EFCAB13 AQP4 ULK3 PLA2R1	1.66e-04	197	116	5	0f37afad46b94c748a149d9ee681472d7a3e6937
ToppCell	COVID-19_Moderate-T/NK_proliferative\|COVID-19_Moderate / disease group, cell group and cell class	NCAPD3 EME1 FANCD2 CDCA5 RAD54L	1.69e-04	198	116	5	166c000fb0e19602ffdd8bf2b2f19be2c6df96a6
ToppCell	COVID-19_Moderate-T/NK_proliferative\|World / disease group, cell group and cell class	NCAPD3 EME1 FANCD2 CDCA5 RAD54L	1.69e-04	198	116	5	bf0131fbca6032e1aab4aa807f8c1d3be689cb7f
ToppCell	facs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IPO7 DSG3 ALKBH5 FREM2 TAOK1	1.69e-04	198	116	5	22559b161e67b49fe8028bfaf861e069063599f5
ToppCell	distal-Hematologic-Proliferating_Macrophage-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NCAPD3 EME1 FANCD2 CDCA5 RAD54L	1.69e-04	198	116	5	8afeb1f9bc9d8551482c8fefe4c5f88d9cd13ee2
ToppCell	distal-Hematologic-Proliferating_Macrophage-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NCAPD3 EME1 FANCD2 CDCA5 RAD54L	1.69e-04	198	116	5	2b0716e900bce54ad1825d6dcdaf4ebf31f355c4
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma\|TCGA-Bladder / Sample_Type by Project: Shred V9	HTRA3 TREM2 GALNT6 MAD2L2 CDCA5	1.69e-04	198	116	5	65875fbd99393cdd62595c713ab90db06d28081f
ToppCell	TCGA-Ovary-Primary_Tumor\|TCGA-Ovary / Sample_Type by Project: Shred V9	HTRA1 HECTD3 CDC42BPB TMEM87A	1.70e-04	106	116	4	14f548be39cec604fbdae0382cbf434fa4049840
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma\|TCGA-Ovary / Sample_Type by Project: Shred V9	HTRA1 HECTD3 CDC42BPB TMEM87A	1.70e-04	106	116	4	939b80950d39cdc7149a05fdfb64c8810064cdb1
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma\|TCGA-Ovary / Sample_Type by Project: Shred V9	HTRA1 HECTD3 CDC42BPB TMEM87A	1.70e-04	106	116	4	e9e1b55f32b3d5b9eeec94a997912e5c21c1fb48
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2_proliferating-AT2_proliferating_L.0.1.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFTPC AQP4 MALL CDCA5 RAD54L	1.73e-04	199	116	5	d7dbc551c05da32c698908348572fb0ce1166e10
ToppCell	facs-Tongue-nan-3m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IPO7 DSG3 PTBP1 ALKBH5 TAOK1	1.73e-04	199	116	5	8d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCell	Biopsy_Other_PF-Epithelial-AT2\|Biopsy_Other_PF / Sample group, Lineage and Cell type	SFTPC SYNE1 AQP4 FREM2 MALL	1.73e-04	199	116	5	9a65acfe9bf500db72142469cf17bf0973540001
ToppCell	Biopsy_Control_(H.)-Epithelial-Proliferating_Epithelial_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	EME1 FANCD2 MALL CDCA5 RAD54L	1.73e-04	199	116	5	4fcf5bec207e4384fd73c5e8801a7e414e3ee7b0
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFTPC AQP4 MALL CDCA5 RAD54L	1.73e-04	199	116	5	6a89c3a65fa50af92585c52bec203bcff6f94efc
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EME1 FAM161A NTM CDCA5 RAD54L	1.73e-04	199	116	5	1d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFTPC SYNE1 AQP4 TMEM87A FREM2	1.73e-04	199	116	5	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NCAPD3 EME1 FANCD2 CDCA5 RAD54L	1.73e-04	199	116	5	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	Mild-T/NK_proliferative\|Mild / Disease group and Cell class	NCAPD3 EME1 FANCD2 CDCA5 RAD54L	1.73e-04	199	116	5	64a5c91243ee999ea21ffddd450d3e5fdbf6470b
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	NCAPD3 PTBP1 FANCD2 NUP155 RAD54L	1.78e-04	200	116	5	d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCell	distal-Hematologic-Proliferating_Macrophage\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NCAPD3 EME1 FANCD2 CDCA5 RAD54L	1.78e-04	200	116	5	3835a8a9739b8cd5bf19c40765ef76907ac1ad38
ToppCell	Biopsy_IPF-Epithelial-Proliferating_Epithelial_cells\|Biopsy_IPF / Sample group, Lineage and Cell type	EME1 AQP4 FANCD2 CDCA5 RAD54L	1.78e-04	200	116	5	63c5402f050fdb12abab3c8b7f33d4914ae26b9b
ToppCell	Hematolymphoid-Microglia-TYROBP----L1-3\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HTRA1 DOCK11 DOCK10 HIVEP3 PKN2	1.78e-04	200	116	5	a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCell	Lung_Parenchyma-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SFTPC SYNE1 AQP4 FREM2 MALL	1.78e-04	200	116	5	c2bde99b3bc7a8740441c1a0c1394892b940b857
ToppCell	Hematolymphoid-Microglia-TYROBP--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HTRA1 DOCK11 DOCK10 HIVEP3 PKN2	1.78e-04	200	116	5	dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DAG1 FRYL MALL MOV10L1 DCLK2	1.78e-04	200	116	5	a8b59e6fe04271fef61db911a286b5c48438bb84
ToppCell	Hematolymphoid-Microglia-TYROBP-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HTRA1 DOCK11 DOCK10 HIVEP3 PKN2	1.78e-04	200	116	5	3bba5219453322198e8fdb0921d5f8c403598751
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SFTPC SYNE1 AQP4 FREM2 MALL	1.78e-04	200	116	5	3ff9abd5e07780a59d5571da906fa15f00a1d5c2
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	NCAPD3 PTBP1 FANCD2 NUP155 RAD54L	1.78e-04	200	116	5	3d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Macroglial\|6m / Sample Type, Dataset, Time_group, and Cell type.	HTRA1 HAGHL AQP4 DCLK2 DCLK1	1.78e-04	200	116	5	42dc8ed66a021097e703eef2d756607396ca2f56
ToppCell	distal-Hematologic-Proliferating_Macrophage-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NCAPD3 EME1 FANCD2 CDCA5 RAD54L	1.78e-04	200	116	5	9c03a8da12d29618f72c429836c1d1bd84a78b12
ToppCell	Hematolymphoid-Microglia\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HTRA1 DOCK11 DOCK10 HIVEP3 PKN2	1.78e-04	200	116	5	21bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCell	Biopsy_Other_PF-Immune-Proliferating_Macrophages\|Biopsy_Other_PF / Sample group, Lineage and Cell type	NCAPD3 EME1 FANCD2 CDCA5 RAD54L	1.78e-04	200	116	5	61473e8613f39a92002d5b631e6bd563735566e4
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NCAPD3 EME1 FANCD2 RAD54B RAD54L	1.78e-04	200	116	5	af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCell	Hematolymphoid-Microglia-TYROBP---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HTRA1 DOCK11 DOCK10 HIVEP3 PKN2	1.78e-04	200	116	5	a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCell	Hematolymphoid-Microglia-TYROBP\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HTRA1 DOCK11 DOCK10 HIVEP3 PKN2	1.78e-04	200	116	5	33036d21c1c82109284473a515c4f890b33fdd5c
Disease	dyslexia (implicated_via_orthology)	DCLK2 DCLK1	1.40e-05	2	111	2	DOID:4428 (implicated_via_orthology)
Disease	Lymphoma, non-Hodgkin, familial	RAD54B RAD54L	1.39e-04	5	111	2	cv:C4721532
Disease	Cerebellar Ataxia	SYNE1 SNX14	1.39e-04	5	111	2	C0007758
Disease	Non-Hodgkin lymphoma	RAD54B RAD54L	1.39e-04	5	111	2	cv:C0024305
Disease	LYMPHOMA, NON-HODGKIN, FAMILIAL	RAD54B RAD54L	1.39e-04	5	111	2	605027
Disease	Polycystic kidney disease, type 2	GANAB BRD4	2.91e-04	7	111	2	C2751306
Disease	colon cancer (is_implicated_in)	KDM3A HTRA1 BRD4	3.38e-04	36	111	3	DOID:219 (is_implicated_in)
Disease	muscular dystrophy-dystroglycanopathy type B1 (implicated_via_orthology)	DAG1 POMT1	3.87e-04	8	111	2	DOID:0050588 (implicated_via_orthology)
Disease	Polycystic Kidney, Type 1 Autosomal Dominant Disease	GANAB BRD4	3.87e-04	8	111	2	C0887850
Disease	Polycystic Kidney, Autosomal Dominant	GANAB BRD4	4.96e-04	9	111	2	C0085413
Disease	MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2K	DAG1 POMT1	1.24e-03	14	111	2	C1836373
Disease	alpha-Dystroglycanopathies	DAG1 POMT1	1.24e-03	14	111	2	C2936406
Disease	Muscle eye brain disease	DAG1 POMT1	1.24e-03	14	111	2	C0457133
Disease	Fukuyama Type Congenital Muscular Dystrophy	DAG1 POMT1	1.24e-03	14	111	2	C0410174
Disease	Muscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies) Type A, 1	DAG1 POMT1	1.24e-03	14	111	2	C4284790
Disease	Walker-Warburg congenital muscular dystrophy	DAG1 POMT1	1.43e-03	15	111	2	C0265221
Disease	Intellectual Disability	FRMPD4 SYNE1 UROC1 CDK10 SNX14 BRD4 TAOK1	1.54e-03	447	111	7	C3714756
Disease	urolithiasis	RSPH14 PDILT VPS13B	1.75e-03	63	111	3	MONDO_0024647
Disease	non-Hodgkin lymphoma (is_implicated_in)	RAD54B RAD54L	1.84e-03	17	111	2	DOID:0060060 (is_implicated_in)
Disease	Dementia	HTRA1 TREM2	1.84e-03	17	111	2	C0497327
Disease	muscular dystrophy (is_implicated_in)	SYNE1 POMT1	1.84e-03	17	111	2	DOID:9884 (is_implicated_in)
Disease	low density lipoprotein cholesterol measurement, body fat percentage	EFCAB13 CCDC92	1.84e-03	17	111	2	EFO_0004611, EFO_0007800
Disease	Alzheimer disease, brain volume measurement	PDS5B PKN2	1.84e-03	17	111	2	EFO_0006930, MONDO_0004975
Disease	parahippocampal gyrus volume measurement	FREM2 SORD	2.06e-03	18	111	2	EFO_0010318
Disease	MYELODYSPLASTIC SYNDROME	FANCD2 SF3B1 MAD2L2	2.08e-03	67	111	3	C3463824
Disease	Alopecia	HTRA1 BRD4	2.30e-03	19	111	2	C0002170
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	PDS5B CCDC92 HIVEP3 MST1R NTM PDILT	2.59e-03	364	111	6	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	Low Grade Lymphoma (neoplasm)	RAD54B RAD54L	2.81e-03	21	111	2	C0079747
Disease	Lymphoma, Intermediate-Grade	RAD54B RAD54L	2.81e-03	21	111	2	C0079741
Disease	High Grade Lymphoma (neoplasm)	RAD54B RAD54L	2.81e-03	21	111	2	C0079740
Disease	Diffuse Mixed-Cell Lymphoma	RAD54B RAD54L	2.81e-03	21	111	2	C0079757
Disease	Lymphoma, Undifferentiated	RAD54B RAD54L	2.81e-03	21	111	2	C0024306
Disease	Reticulosarcoma	RAD54B RAD54L	2.81e-03	21	111	2	C0024302
Disease	Lymphoma, Mixed-Cell	RAD54B RAD54L	2.81e-03	21	111	2	C0024304
Disease	Lymphoma, Diffuse	RAD54B RAD54L	2.81e-03	21	111	2	C3714542
Disease	Lymphoma, Non-Hodgkin, Familial	RAD54B RAD54L	3.08e-03	22	111	2	C4721532
Disease	Lymphoma, Small Noncleaved-Cell	RAD54B RAD54L	3.08e-03	22	111	2	C0079770
Disease	Hepatitis	PDS5B NTM	3.08e-03	22	111	2	HP_0012115
Disease	Nasopharyngeal carcinoma	SYNE1 MST1R	3.08e-03	22	111	2	C2931822

Protein segments in the cluster

Peptide	Gene	Start	Entry
HRIIKETQRLLAEPV	UBE2NL	6	Q5JXB2
DLILKPGVVHVIDVD	AQP4	291	P55087
KPIVLKRIVAHAVEV	CDCA5	56	Q96FF9
IPKHIPERVSLVVTE	PRMT9	241	Q6P2P2
PLVVVKEEKIHSPII	BRD4	1106	O60885
LVIQKLVEHRVIPEG	ALKBH5	171	Q6P6C2
PEVADKIVLVADRHL	CFAP46	2321	Q8IYW2
LTEPVVVLEGHTKRV	CORO1B	121	Q9BR76
TVPLLHAAIREVDIK	SORD	281	Q00796
IVDPEIALKILHRQT	CSTF2	181	P33240
PIHITIVRLVLLEDE	ADAMTS7	286	Q9UKP4
LAVIHELRPTEKVVL	RAD54B	651	Q9Y620
IKFLLERIAPVHIDT	PDS5B	601	Q9NTI5
ILVRKELEEIARTHP	CYB5R2	191	Q6BCY4
VHVVVDPILSKVLRP	RAD54L	141	Q92698
VAVDVAVPKRLLEIV	HAGHL	26	Q6PII5
PIRDIEIIHEELQLK	OLA1	141	Q9NTK5
ELRALSHVLKTPIEV	OTUD6A	221	Q7L8S5
VVVILVHGELRIETK	DSG3	16	P32926
HDNIIAIKDILRPTV	MAPK7	111	Q13164
VPIIHRDLKSINILI	MAP3K10	216	Q02779
VPVIIARTDHIIVKE	MFAP3L	46	O75121
IHLGVKVLFPEEIIL	MOV10L1	651	Q9BXT6
EKVVVVILDKEHRPV	MAD2L2	81	Q9UI95
VHATIVSEKLLDPRI	MALL	111	Q13021
LPRLHLVPAEKAVEV	MGA	201	Q8IWI9
SRVHLIVQVSPKIVE	NTM	126	Q9P121
HSVEKTVLIIVIPVD	FREM2	1286	Q5SZK8
EVSILRRVKHPNIVL	DCLK1	436	O15075
LIENEVSILRRVKHP	DCLK2	436	Q8N568
LHTVIPAVVVAAILL	DAG1	751	Q14118
LLPEREVHVLEHTKI	PDC	226	P20941
VEAIIHSPELIRVQL	IPO7	96	O95373
TEHPKLLRVLSVEAI	FAM205A	756	Q6ZU69
TEHPKLLRVLSVEAI	FAM205BP	486	Q63HN1
IHKLFAPVRISITLV	FAM210B	156	Q96KR6
LIEELHPIIKEALER	FRYL	951	O94915
AHVTDPRVVDLLVIK	NDUFA6	71	P56556
VNPLSLVEIILHVVR	PSMD13	71	Q9UNM6
VHQIELAPREKIVIL	CDC42BPB	1281	Q9Y5S2
LVKILHHLEEPVIFI	FAAP100	271	Q0VG06
VRHLLVLATPVDIVI	NUP155	161	O75694
LLVLTVVIEKREHSP	DCHS2	1066	Q6V1P9
HLLARAVALLVIPVV	POMT1	261	Q9Y6A1
RASALAEHIKPVVVI	HIP1R	291	O75146
VVEKIAPAVVHIELF	HTRA3	146	P83110
VEKIAPAVVHIELFR	HTRA1	176	Q92743
LKIVDPSLIHVEVVH	KDM3A	231	Q9Y4C1
PHSEIVLVAKIEKVL	DOCK10	501	Q96BY6
PHPEIFLVARIEKVL	DOCK11	471	Q5JSL3
LRLRHPNIVELKEVV	CDK10	91	Q15131
HIDIPRVQLLIEDKE	DSCAML1	1656	Q8TD84
EVLLREVLPEHVSVL	EPM2AIP1	126	Q7L775
ESAEVHLIKERPLVI	CCDC92	251	Q53HC0
RVELHVLDVKPITLL	FRMPD4	481	Q14CM0
LHTTPAILLKEIILV	GALNT6	201	Q8NCL4
IPINREILEEVTKHT	EFCAB13	251	Q8IY85
EECLKHIIVVLDPVL	EME1	246	Q96AY2
LHLKEVQPVVIREDS	FAM161A	121	Q3B820
VAPLTITHVREKAID	GRIK3	516	Q13003
EHTILHLPEKIRPEI	FOCAD	721	Q5VW36
EDLPVIIKFILHSVT	FANCD2	276	Q9BXW9
ILVRIPGEIIVAHIE	OTOGL	1561	Q3ZCN5
VHLKRLLIVVVVVVL	SFTPC	31	P11686
EVISVPHKIITHLRK	MTX1	211	Q13505
KVEAVIHPRFLEELL	NUTM2F	456	A1L443
KVEAVIHPRFLEELL	NUTM2G	441	Q5VZR2
IHITKPVHILEERSL	PDILT	31	Q8N807
FPTLRHEILELIIEK	RRN3	236	Q9NYV6
ESSELLHLVPVERVK	UTP20	576	O75691
LHLVPVERVKNLVLT	UTP20	581	O75691
IEVLPKETLRHEILN	PPP4R4	161	Q6NUP7
VIHAIRPELVDLETV	SYNE1	216	Q8NF91
PVHVAFERLELKELI	MAP3K21	116	Q5TCX8
PLVLTVEHKEKELIV	PIWIL2	201	Q8TC59
VHLIHEVTKVLLVLE	GANAB	76	Q14697
SRIVTHDIPIKVIPR	HUS1	126	O60921
RIDEVAVPVHVAKIL	POLR3A	376	O14802
VELHLRVPLEKEIPV	SENP1	386	Q9P0U3
PPREIVAHIIQKILL	SIMC1	501	Q8NDZ2
LTIIEATHVLLVEPI	SHPRH	1591	Q149N8
PTIVHRFLIKATIEE	SHPRH	1626	Q149N8
IPEEVREHVKLLLNV	SCYL2	296	Q6P3W7
LKHIFVLRERPETVL	TAOK1	276	Q7L7X3
HPKSRIIIEELSLVA	PKN2	286	Q16513
ILVPVSIGIVIKHRI	SLC10A5	281	Q5PT55
HSIIPLAVVLTLIVI	PLA2R1	1396	Q13018
AVLHQPLKVIREILV	SEC24D	796	O94855
HLIIPLREVTIVEKA	TBC1D9B	341	Q66K14
IAIKQTPELTLHEIV	ADAMDEC1	31	O15204
KESIFPVVRILLQHI	NCAPD3	346	P42695
VQELVHPVVDRSIKI	CNOT1	1401	A5YKK6
IVHRDLKPDNILITE	STK35	356	Q8TDR2
LRPETHTKEQILELV	ZNF24	81	P17028
IIKLQTHDIIEVPTR	WASHC5	641	Q12768
PEIHTKEQILELLVL	ZSCAN21	76	Q9Y5A6
VLIRRIHKVDIPSII	SNX14	176	Q9Y5W7
DVIPILVHLLKDPVE	RSPH14	231	Q9UHP6
LVVTLPHKVEDERVL	UROC1	656	Q96N76
VHKILVVIEPLLIDE	SF3B1	571	O75533
DVEHEIIKRINPILT	STOX1	356	Q6ZVD7
IEVPHKLLERVTFVD	SRL	176	Q86TD4
VVLPKHILDIWVIVL	SMIM3	11	Q9BZL3
VPRTQVIEHITKLIT	HIVEP3	456	Q5T1R4
VLVKRKLVHDIIDLI	TTLL2	401	Q9BWV7
LRKVLVEVLADPLDH	TREM2	121	Q9NZC2
DIHIPAVILKTFLRE	ARHGAP8	291	P85298
IRILVDKINLEHSVP	VPS13B	691	Q7Z7G8
RLVVKSIEPLHVSVF	PLEKHG7	611	Q6ZR37
LRPEVHTKEQILELL	ZNF396	81	Q96N95
LRLHQLVETVELKIP	RAPGEFL1	266	Q9UHV5
IVVISLLTKPIPDVH	SLC5A1	541	P13866
VRTVIVPSEKVVDLL	ARHGAP21	271	Q5T5U3
VPSRVIHIRKLPIDV	PTBP1	56	P26599
IHIRKLPIDVTEGEV	PTBP1	61	P26599
RPETHTKEQILELLV	ZSCAN12	76	O43309
LLAEVKDVLIPHERV	MST1R	1066	Q04912
SELVVKTLIVAEPHV	TTLL7	296	Q6ZT98
IVKPRLGVTLHKVVV	TMEM87A	321	Q8NBN3
TEIEILKGIRHPHIV	ULK3	61	Q6PHR2
DMTVHLPIIEIRIVE	HECTD3	341	Q5T447