Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ribonucleoside-diphosphate reductase activity	RRM2B RRM1 RRM2	3.91e-07	3	147	3	GO:0061731
GeneOntologyMolecularFunction	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	RRM2B RRM1 RRM2	3.91e-07	3	147	3	GO:0004748
GeneOntologyMolecularFunction	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	RRM2B RRM1 RRM2	3.87e-06	5	147	3	GO:0016728
GeneOntologyMolecularFunction	ATP-dependent activity	MYH10 SETX MYO1E ABCA13 CFTR NVL ABCC11 MYO5C ORC1 SLC27A1 CHD5 ABCB11 RFT1 MTREX ATP1B1 DNAH8	1.23e-05	614	147	16	GO:0140657
GeneOntologyMolecularFunction	oxidoreductase activity, acting on CH or CH2 groups	RRM2B RRM1 RRM2	1.67e-04	15	147	3	GO:0016725
GeneOntologyMolecularFunction	DNA endonuclease activity	ERCC4 XRCC4 EXO1 DNASE1L3	3.04e-04	44	147	4	GO:0004520
GeneOntologyMolecularFunction	ABC-type bile acid transporter activity	ABCC11 ABCB11	3.20e-04	4	147	2	GO:0015432
GeneOntologyMolecularFunction	3' overhang single-stranded DNA endodeoxyribonuclease activity	ERCC4 XRCC4	3.20e-04	4	147	2	GO:1990599
GeneOntologyMolecularFunction	ATPase-coupled organic acid transmembrane transporter activity	ABCC11 ABCB11	3.20e-04	4	147	2	GO:0033283
GeneOntologyMolecularFunction	ATPase-coupled monocarboxylic acid transmembrane transporter activity	ABCC11 ABCB11	3.20e-04	4	147	2	GO:0033285
GeneOntologyMolecularFunction	ATPase-coupled carboxylic acid transmembrane transporter activity	ABCC11 ABCB11	3.20e-04	4	147	2	GO:0033284
GeneOntologyMolecularFunction	calcium ion binding	CALB2 PNLIPRP1 PCDHGB2 CETN1 RCN1 PCDHA1 EFCAB3 ITPR2 DUOX1 PPP3R2 ADGRE5 UNC13C DNASE1L3 UNC13A CDH13	4.26e-04	749	147	15	GO:0005509
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA13 CFTR ABCC11 ABCB11	4.62e-04	49	147	4	GO:0140359
GeneOntologyBiologicalProcess	2'-deoxyribonucleotide biosynthetic process	RRM2B RRM1 RRM2 ADK	8.60e-06	19	146	4	GO:0009265
GeneOntologyBiologicalProcess	deoxyribonucleotide biosynthetic process	RRM2B RRM1 RRM2 ADK	8.60e-06	19	146	4	GO:0009263
GeneOntologyBiologicalProcess	deoxyribose phosphate biosynthetic process	RRM2B RRM1 RRM2 ADK	8.60e-06	19	146	4	GO:0046385
GeneOntologyBiologicalProcess	positive regulation of G0 to G1 transition	RRM2B RRM1 ORC1	1.90e-05	8	146	3	GO:0070318
GeneOntologyBiologicalProcess	negative regulation of telomere capping	ERCC4 XRCC4 ATM	2.83e-05	9	146	3	GO:1904354
GeneOntologyBiologicalProcess	regulation of telomere capping	ERCC4 XRCC4 NEK2 ATM	3.72e-05	27	146	4	GO:1904353
GeneOntologyBiologicalProcess	2'-deoxyribonucleotide metabolic process	RRM2B RRM1 RRM2 ADA ADK	4.34e-05	55	146	5	GO:0009394
GeneOntologyBiologicalProcess	deoxyribose phosphate metabolic process	RRM2B RRM1 RRM2 ADA ADK	4.74e-05	56	146	5	GO:0019692
GeneOntologyBiologicalProcess	deoxyribonucleotide metabolic process	RRM2B RRM1 RRM2 ADA ADK	5.17e-05	57	146	5	GO:0009262
GeneOntologyBiologicalProcess	deoxyribonucleoside triphosphate metabolic process	RRM2B ADA ADK	9.43e-05	13	146	3	GO:0009200
GeneOntologyBiologicalProcess	regulation of G2/M transition of mitotic cell cycle	MIIP RRM2B RRM1 ORC1 ATM USP47	1.78e-04	116	146	6	GO:0010389
GeneOntologyBiologicalProcess	telomere capping	ERCC4 XRCC4 NEK2 ATM	1.99e-04	41	146	4	GO:0016233
GeneOntologyBiologicalProcess	regulation of G0 to G1 transition	RRM2B RRM1 ORC1 SMARCE1	2.19e-04	42	146	4	GO:0070316
GeneOntologyBiologicalProcess	G0 to G1 transition	RRM2B RRM1 ORC1 SMARCE1	2.62e-04	44	146	4	GO:0045023
GeneOntologyBiologicalProcess	telomeric DNA-containing double minutes formation	ERCC4 XRCC4	2.96e-04	4	146	2	GO:0061819
GeneOntologyBiologicalProcess	dense core granule priming	UNC13C UNC13A	2.96e-04	4	146	2	GO:0061789
GeneOntologyBiologicalProcess	negative regulation of protection from non-homologous end joining at telomere	ERCC4 XRCC4	2.96e-04	4	146	2	GO:1905765
GeneOntologyBiologicalProcess	regulation of protection from non-homologous end joining at telomere	ERCC4 XRCC4	2.96e-04	4	146	2	GO:1905764
GeneOntologyBiologicalProcess	central nervous system development	CUL4B EEF1AKMT4-ECE2 MYH10 GAK NAPA POU3F1 POU3F2 GRIK1 POU6F1 XRCC4 RRM1 OPHN1 SERPINI1 GRK2 CHD5 TLR4 DOCK7 PLXNA4 ATM DMD	3.02e-04	1197	146	20	GO:0007417
GeneOntologyCellularComponent	ribonucleoside-diphosphate reductase complex	RRM2B RRM1 RRM2	3.34e-07	3	146	3	GO:0005971
GeneOntologyCellularComponent	anchoring junction	FLII GAK CALB2 MYO1E DSP ARHGAP26 FBF1 ADA YES1 P4HB EPHA2 DOCK7 ABCB11 ADGRE5 DMD ATP1B1 MAPRE2 ARHGEF6 CDH13	5.10e-05	976	146	19	GO:0070161
GeneOntologyCellularComponent	cell-substrate junction	FLII GAK ARHGAP26 YES1 P4HB EPHA2 DOCK7 ADGRE5 DMD MAPRE2 CDH13	2.88e-04	443	146	11	GO:0030055
GeneOntologyCellularComponent	ERCC4-ERCC1 complex	ERCC4 XRCC4	4.78e-04	5	146	2	GO:0070522
GeneOntologyCellularComponent	terminal bouton	CALB2 GRIK1 OPHN1 UNC13C UNC13A	5.69e-04	96	146	5	GO:0043195
Domain	RNR-rel	RRM2B RRM2	5.74e-05	2	142	2	IPR012348
Domain	RNR_small_fam	RRM2B RRM2	5.74e-05	2	142	2	IPR000358
Domain	RNR_small	RRM2B RRM2	5.74e-05	2	142	2	IPR033909
Domain	-	RRM2B RRM2	5.74e-05	2	142	2	1.10.620.20
Domain	RNR_small_AS	RRM2B RRM2	5.74e-05	2	142	2	IPR030475
Domain	Ribonuc_red_sm	RRM2B RRM2	5.74e-05	2	142	2	PF00268
Domain	RIBORED_SMALL	RRM2B RRM2	5.74e-05	2	142	2	PS00368
Domain	AAA	ABCA13 CFTR NVL ABCC11 ORC1 ABCB11 DNAH8	1.17e-04	144	142	7	SM00382
Domain	AAA+_ATPase	ABCA13 CFTR NVL ABCC11 ORC1 ABCB11 DNAH8	1.17e-04	144	142	7	IPR003593
Domain	RPAP3-like_C	SPAG1 RPAP3	1.71e-04	3	142	2	IPR025986
Domain	RPAP3_C	SPAG1 RPAP3	1.71e-04	3	142	2	PF13877
Domain	Unc-13	UNC13C UNC13A	1.71e-04	3	142	2	IPR027080
Domain	POU	POU3F1 POU3F2 POU6F1	2.24e-04	16	142	3	SM00352
Domain	POU_dom	POU3F1 POU3F2 POU6F1	2.24e-04	16	142	3	IPR000327
Domain	Pou	POU3F1 POU3F2 POU6F1	2.24e-04	16	142	3	PF00157
Domain	POU_1	POU3F1 POU3F2 POU6F1	2.24e-04	16	142	3	PS00035
Domain	POU_2	POU3F1 POU3F2 POU6F1	2.24e-04	16	142	3	PS00465
Domain	POU_3	POU3F1 POU3F2 POU6F1	2.24e-04	16	142	3	PS51179
Domain	POU	POU3F1 POU3F2 POU6F1	2.71e-04	17	142	3	IPR013847
Domain	TF_POU_3	POU3F1 POU3F2	3.41e-04	4	142	2	IPR016362
Domain	ABC_tran	ABCA13 CFTR ABCC11 ABCB11	4.81e-04	48	142	4	PF00005
Domain	ABC_TRANSPORTER_2	ABCA13 CFTR ABCC11 ABCB11	4.81e-04	48	142	4	PS50893
Domain	ABC_TRANSPORTER_1	ABCA13 CFTR ABCC11 ABCB11	5.20e-04	49	142	4	PS00211
Domain	ABC_transporter-like	ABCA13 CFTR ABCC11 ABCB11	5.62e-04	50	142	4	IPR003439
Domain	Munc13_dom-2	UNC13C UNC13A	5.65e-04	5	142	2	IPR014772
Domain	MHD2	UNC13C UNC13A	5.65e-04	5	142	2	PS51259
Domain	Munc13_subgr_dom-2	UNC13C UNC13A	5.65e-04	5	142	2	IPR019558
Domain	Myosin_S1_N	MYH10 MYO5C	5.65e-04	5	142	2	IPR008989
Domain	Membr_traf_MHD	UNC13C UNC13A	5.65e-04	5	142	2	PF10540
Domain	DUF1041	UNC13C UNC13A	5.65e-04	5	142	2	SM01145
Domain	P-loop_NTPase	MYH10 SETX MYO1E ABCA13 CFTR NVL ABCC11 AAGAB NLRP2 MYO5C ORC1 CIITA CHD5 ABCB11 MTREX DNAH8	7.31e-04	848	142	16	IPR027417
Domain	ABC_membrane	CFTR ABCC11 ABCB11	7.75e-04	24	142	3	PF00664
Domain	LRR_6	KERA NLRP2 CIITA TLR4	8.09e-04	55	142	4	PF13516
Domain	LRR	FLII KERA LRRC8D CIITA TLR4 XRRA1 LRRC17	8.80e-04	201	142	7	PS51450
Domain	EF-hand_1	CALB2 CETN1 RCN1 EFCAB3 DUOX1 PPP3R2	1.09e-03	152	142	6	PF00036
Domain	-	POU3F1 POU3F2 POU6F1	1.10e-03	27	142	3	1.10.260.40
Domain	Leu-rich_rpt	FLII KERA NLRP2 LRRC8D CIITA TLR4 XRRA1 LRRC17	1.11e-03	271	142	8	IPR001611
Domain	Munc13_1	UNC13C UNC13A	1.18e-03	7	142	2	IPR014770
Domain	MHD1	UNC13C UNC13A	1.18e-03	7	142	2	PS51258
Domain	DUF1041	UNC13C UNC13A	1.18e-03	7	142	2	PF06292
Domain	CAPS_dom	UNC13C UNC13A	1.18e-03	7	142	2	IPR010439
Domain	ABC_TM1F	CFTR ABCC11 ABCB11	1.23e-03	28	142	3	PS50929
Domain	ABC1_TM_dom	CFTR ABCC11 ABCB11	1.23e-03	28	142	3	IPR011527
Domain	Lambda_DNA-bd_dom	POU3F1 POU3F2 POU6F1	1.36e-03	29	142	3	IPR010982
Domain	Spectrin_repeat	DSP SPTBN5 DMD	1.36e-03	29	142	3	IPR002017
Domain	LRR_1	FLII KERA LRRC8D CIITA TLR4 XRRA1 LRRC17	1.45e-03	219	142	7	PF00560
Domain	SPEC	DSP SPTBN5 DMD	1.82e-03	32	142	3	SM00150
Domain	Spectrin/alpha-actinin	DSP SPTBN5 DMD	1.82e-03	32	142	3	IPR018159
Domain	CH	SPTBN5 DMD MAPRE2 ARHGEF6	1.99e-03	70	142	4	PF00307
Domain	-	SPTBN5 DMD MAPRE2 ARHGEF6	2.10e-03	71	142	4	1.10.418.10
Domain	EF_Hand_1_Ca_BS	CALB2 CETN1 RCN1 EFCAB3 DUOX1 PPP3R2	2.22e-03	175	142	6	IPR018247
Domain	CH	SPTBN5 DMD MAPRE2 ARHGEF6	2.32e-03	73	142	4	PS50021
Domain	LRR_TYP	FLII KERA LRRC8D TLR4 XRRA1 LRRC17	2.35e-03	177	142	6	SM00369
Domain	Leu-rich_rpt_typical-subtyp	FLII KERA LRRC8D TLR4 XRRA1 LRRC17	2.35e-03	177	142	6	IPR003591
Pubmed	A Large-scale genetic association study of esophageal adenocarcinoma risk.	ERCC4 CFTR CASP10 GRIK1 XRCC4 RRM1 PTPN13 EXO1 ABCB11 MTRR ATM ATP1B1	3.67e-08	351	147	12	20453000
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	FLII MYH10 GAK DNAJC13 VWF OXR1 MYO1E DSP ARHGAP26 ARHGEF17 PGM1 OPHN1 ITPR2 MLXIPL GRK2 AP1G1 P4HB SLC27A1 DOCK7 PLXNA4 DMD ATP1B1 UNC13A	3.78e-08	1431	147	23	37142655
Pubmed	Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion.	RRM2B RRM1 RRM2	7.40e-08	3	147	3	17486094
Pubmed	Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage.	RRM2B RRM1 RRM2	7.40e-08	3	147	3	18997010
Pubmed	In vitro characterization of enzymatic properties and inhibition of the p53R2 subunit of human ribonucleotide reductase.	RRM2B RRM1 RRM2	7.40e-08	3	147	3	14729598
Pubmed	Ribonucleotide reductase expression in cervical cancer: a radiation therapy oncology group translational science analysis.	RRM2B RRM1 RRM2	7.40e-08	3	147	3	23552804
Pubmed	Characterization of enzymatic properties of human ribonucleotide reductase holoenzyme reconstituted in vitro from hRRM1, hRRM2, and p53R2 subunits.	RRM2B RRM1 RRM2	7.40e-08	3	147	3	16376858
Pubmed	The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53.	RRM2B RRM1 RRM2	2.95e-07	4	147	3	14583450
Pubmed	Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase.	RRM2B RRM1 RRM2	2.95e-07	4	147	3	20159953
Pubmed	Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells.	RRM2B RRM1 RRM2	2.95e-07	4	147	3	11517226
Pubmed	Wild-type p53 regulates human ribonucleotide reductase by protein-protein interaction with p53R2 as well as hRRM2 subunits.	RRM2B RRM1 RRM2	2.95e-07	4	147	3	12615712
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	CUL4B FLII MYH10 RPAP3 RCN1 RRM1 MOGS AP1G1 RBM27 PRCC DOCK7 EIF3D MTREX CWF19L1	7.93e-07	653	147	14	33742100
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	MYH10 DNAJC13 SETX DSP MED14 PCDHA1 PTPN13 MOGS TCERG1 RBM27 P4HB CLK3 DOCK7 SMARCE1 ATM EIF3D UNC13A ARHGEF6	8.04e-07	1082	147	18	38697112
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	RCN1 ARFGEF1 MANEA HMOX2 RRM1 LRRC8D ITPR2 SERPINI1 MOGS P4HB EPHA2 SMARCE1 ADGRE5 ATM RFT1 ATP1B1 CDH13 PCYOX1	3.48e-06	1201	147	18	35696571
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ERCC4 SETX ARHGAP26 MPEG1 ZBTB24 PGM1 MFAP3 PTPN13 AP1G1 P4HB AOPEP TLR4 ADGRE5 STK24 ARHGEF6 LRRC17 TGS1	3.66e-06	1084	147	17	11544199
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	FLII IRF2BP1 DSP VPS13C MED14 CASP10 POU3F1 MUC13 RNF17 AP1G1 P4HB SMARCE1 DMD ZMYM4	4.21e-06	754	147	14	35906200
Pubmed	Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	CUL4B DNAJC13 SETX ARHGAP26 MFAP3L AKAP11	4.96e-06	102	147	6	9734811
Pubmed	LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.	CUL4B FLII MYH10 MYO1E DSP MUC13 YES1 P4HB EPHA2 DOCK7 STK24 CDH13	7.20e-06	580	147	12	35676659
Pubmed	Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.	ERCC4 CASP10 XRCC4 NLRP2 EXO1 MTRR ATM	1.18e-05	179	147	7	19074885
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	CUL4B SPAG1 DNAJC13 IRF2BP1 MYO1E RPAP3 ARHGAP26 XRCC4 PTPN13 GPBP1L1 P4HB PRCC DOCK7 EIF3D RFT1 MAPRE2 CSPP1 ARHGEF6	1.27e-05	1321	147	18	27173435
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	ERCC4 SETX IRF2BP1 ITPR2 AP1G1 P4HB ATM ZMYM4	1.68e-05	262	147	8	36880596
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	GAK DNAJC13 RPAP3 RCN1 NVL HMOX2 RRM1 ADA YES1 ITPR2 PTPN13 THEM4 MOGS P4HB PRCC EPHA2 AKAP11 ATM CSPP1	1.76e-05	1487	147	19	33957083
Pubmed	Investigation of the association of hRRM1 and p53R2 gene polymorphisms in head and neck squamous cell carcinomas.	RRM2B RRM1	1.77e-05	2	147	2	24861915
Pubmed	The influence of Flightless I on Toll-like-receptor-mediated inflammation in a murine model of diabetic wound healing.	FLII TLR4	1.77e-05	2	147	2	23555084
Pubmed	Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks.	EXO1 ATM	1.77e-05	2	147	2	20019063
Pubmed	RRM1 and RRM2 pharmacogenetics: association with phenotypes in HapMap cell lines and acute myeloid leukemia patients.	RRM1 RRM2	1.77e-05	2	147	2	24024897
Pubmed	Crystal structural studies of changes in the native dinuclear iron center of ribonucleotide reductase protein R2 from mouse.	RRM2B RRM2	1.77e-05	2	147	2	15322079
Pubmed	A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage.	RRM2B RRM1	1.77e-05	2	147	2	10716435
Pubmed	Isolation and characterization of expressible cDNA clones encoding the M1 and M2 subunits of mouse ribonucleotide reductase.	RRM1 RRM2	1.77e-05	2	147	2	3025593
Pubmed	Caspase-dependent Proteolysis of Human Ribonucleotide Reductase Small Subunits R2 and p53R2 during Apoptosis.	RRM2B RRM2	1.77e-05	2	147	2	25878246
Pubmed	Sequence analysis of the large and small subunits of human ribonucleotide reductase.	RRM1 RRM2	1.77e-05	2	147	2	1627826
Pubmed	Adenosine kinase inhibition promotes survival of fetal adenosine deaminase-deficient thymocytes by blocking dATP accumulation.	ADA ADK	1.77e-05	2	147	2	12163459
Pubmed	A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development.	RRM1 RRM2	1.77e-05	2	147	2	26077802
Pubmed	Enhanced subunit interactions with gemcitabine-5'-diphosphate inhibit ribonucleotide reductases.	RRM1 RRM2	1.77e-05	2	147	2	17726094
Pubmed	GRAF1 deficiency blunts sarcolemmal injury repair and exacerbates cardiac and skeletal muscle pathology in dystrophin-deficient mice.	ARHGAP26 DMD	1.77e-05	2	147	2	26301073
Pubmed	Clofarabine 5'-di and -triphosphates inhibit human ribonucleotide reductase by altering the quaternary structure of its large subunit.	RRM1 RRM2	1.77e-05	2	147	2	21628579
Pubmed	Flightless I homolog negatively regulates ChREBP activity in cancer cells.	FLII MLXIPL	1.77e-05	2	147	2	24055811
Pubmed	RNA structure is a key regulatory element in pathological ATM and CFTR pseudoexon inclusion events.	CFTR ATM	1.77e-05	2	147	2	17580311
Pubmed	Mapping of the ribonucleotide reductase genes (Rrm1, Rrm2) in the rat.	RRM1 RRM2	1.77e-05	2	147	2	9021149
Pubmed	Adenosine deaminase and adenosine kinase expression in human glioma and their correlation with glioma‑associated epilepsy.	ADA ADK	1.77e-05	2	147	2	26329539
Pubmed	von Willebrand factor is dimerized by protein disulfide isomerase.	VWF P4HB	1.77e-05	2	147	2	26670633
Pubmed	Toll-like receptor-4 genotype influences the survival of cystic fibrosis mice.	CFTR TLR4	1.77e-05	2	147	2	20522639
Pubmed	1H NMR studies of mouse ribonucleotide reductase: the R2 protein carboxyl-terminal tail, essential for subunit interaction, is highly flexible but becomes rigid in the presence of protein R1.	RRM1 RRM2	1.77e-05	2	147	2	8130196
Pubmed	Ribonucleotide reductase subunit switching in hepatoblastoma drug response and relapse.	RRM2B RRM2	1.77e-05	2	147	2	36882565
Pubmed	Investigation of some DNA repair genes association in non small cell lung cancer.	RRM1 RRM2	1.77e-05	2	147	2	26718430
Pubmed	Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-κB-mediated inflammatory response in mice.	CFTR TLR4	1.77e-05	2	147	2	21712022
Pubmed	The AAA-ATPase NVL2 is a component of pre-ribosomal particles that interacts with the DExD/H-box RNA helicase DOB1.	NVL MTREX	1.77e-05	2	147	2	16782053
Pubmed	TLR4 Signaling augments monocyte chemotaxis by regulating G protein-coupled receptor kinase 2 translocation.	GRK2 TLR4	1.77e-05	2	147	2	23772028
Pubmed	The involvement of Arg265 of mouse ribonucleotide reductase R2 protein in proton transfer and catalysis.	RRM1 RRM2	1.77e-05	2	147	2	16829694
Pubmed	Expression of RRM1 and RRM2 as a novel prognostic marker in advanced non-small cell lung cancer receiving chemotherapy.	RRM1 RRM2	1.77e-05	2	147	2	24155212
Pubmed	Clinical pharmacology and clinical trials of ribonucleotide reductase inhibitors: is it a viable cancer therapy?	RRM1 RRM2	1.77e-05	2	147	2	28624910
Pubmed	Ribonucleotide reductase subunits M1 and M2 mRNA expression levels and clinical outcome of lung adenocarcinoma patients treated with docetaxel/gemcitabine.	RRM1 RRM2	1.77e-05	2	147	2	18414411
Pubmed	TLR4 is a regulator of trained immunity in a murine model of Duchenne muscular dystrophy.	TLR4 DMD	1.77e-05	2	147	2	35169163
Pubmed	Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication.	RRM2B RRM1	1.77e-05	2	147	2	28416140
Pubmed	Flightless I Negatively Regulates Macrophage Surface TLR4, Delays Early Inflammation, and Impedes Wound Healing.	FLII TLR4	1.77e-05	2	147	2	35883634
Pubmed	TLR-4-mediated innate immunity is reduced in cystic fibrosis airway cells.	CFTR TLR4	1.77e-05	2	147	2	19502387
Pubmed	The conserved Lys-95 charged residue cluster is critical for the homodimerization and enzyme activity of human ribonucleotide reductase small subunit M2.	RRM1 RRM2	1.77e-05	2	147	2	24253041
Pubmed	Transgenic overexpression of ribonucleotide reductase improves cardiac performance.	RRM1 RRM2	1.77e-05	2	147	2	23530224
Pubmed	Enzymatically active mammalian ribonucleotide reductase exists primarily as an alpha6beta2 octamer.	RRM1 RRM2	1.77e-05	2	147	2	16861739
Pubmed	Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis.	CFTR TLR4	1.77e-05	2	147	2	21593379
Pubmed	Gene aberrations of RRM1 and RRM2B and outcome of advanced breast cancer after treatment with docetaxel with or without gemcitabine.	RRM2B RRM1	1.77e-05	2	147	2	24215511
Pubmed	A comprehensive model for the allosteric regulation of mammalian ribonucleotide reductase. Functional consequences of ATP- and dATP-induced oligomerization of the large subunit.	RRM1 RRM2	1.77e-05	2	147	2	11781084
Pubmed	Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization.	RRM1 RRM2	1.77e-05	2	147	2	21336276
Pubmed	Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice.	RRM1 RRM2	1.77e-05	2	147	2	20724444
Pubmed	Expression status of ribonucleotide reductase small subunits hRRM2/p53R2 as prognostic biomarkers in stage I and II non-small cell lung cancer.	RRM2B RRM2	1.77e-05	2	147	2	21965764
Pubmed	Structural basis on the dityrosyl-diiron radical cluster and the functional differences of human ribonucleotide reductase small subunits hp53R2 and hRRM2.	RRM2B RRM2	1.77e-05	2	147	2	20484015
Pubmed	p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint.	RRM2B RRM1	1.77e-05	2	147	2	11719458
Pubmed	BRN2 is a transcriptional repressor of CDH13 (T-cadherin) in melanoma cells.	POU3F2 CDH13	1.77e-05	2	147	2	23069940
Pubmed	Comprehensive model for allosteric regulation of mammalian ribonucleotide reductase: refinements and consequences.	RRM1 RRM2	1.77e-05	2	147	2	12578384
Pubmed	Redox property of ribonucleotide reductase small subunit M2 and p53R2.	RRM2B RRM2	1.77e-05	2	147	2	19082948
Pubmed	Modifier effect of the Toll-like receptor 4 D299G polymorphism in children with cystic fibrosis.	CFTR TLR4	1.77e-05	2	147	2	16830219
Pubmed	Toll-like receptor 4 ablation in mdx mice reveals innate immunity as a therapeutic target in Duchenne muscular dystrophy.	TLR4 DMD	1.77e-05	2	147	2	25552658
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	FLII MYH10 DSP VPS13C NVL RRM2 YES1 MYO5C	1.78e-05	264	147	8	32814769
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MIIP SETX DSP RRM2 ARHGEF17 MLXIPL PTPN13 TCERG1 CLK3 DOCK7 EXO1 AKAP11 MTREX CSPP1	1.86e-05	861	147	14	36931259
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	SPAG1 MYH10 DNAJC13 DSP RRM2B BDH2 ARFGEF1 NAPA RRM1 YES1 PGM1 MOGS AP1G1 P4HB EPHA2 SMARCE1 EIF3D PCYOX1	2.01e-05	1367	147	18	32687490
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	CUL4B MYH10 RRM1 PGM1 GRK2 MOGS AP1G1 ZNF701 EIF3D MTREX	2.38e-05	451	147	10	36168627
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	IRF2BP1 VPS13C RCN1 HMOX2 RRM2 YES1 PTPN13 GRK2 AP1G1 RBM27 P4HB EIF3D CWF19L1 ZMYM4 PCYOX1	2.57e-05	1007	147	15	34597346
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	CUL4B DNAJC13 VWF DSP VPS13C BDH2 NAPA ABCC11 PGM1 PTPN13 MOGS ABCB11 CCDC180 STK24 PCYOX1	2.84e-05	1016	147	15	19056867
Pubmed	Defining the membrane proteome of NK cells.	GAK DNAJC13 MED14 NVL NAPA HMOX2 LRRC8D ITPR2 GRK2 MOGS AP1G1 CLK3 SLC27A1 CHD5 ADGRE5 EIF3D	3.74e-05	1168	147	16	19946888
Pubmed	Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.	MYO1E MYO5C ITPR2 PTPN13 CLK3 DOCK7 RFT1 ATP1B1	4.02e-05	296	147	8	34186245
Pubmed	Hereditary Ataxia Overview	SETX OPHN1 CLN5 ATM CWF19L1	4.61e-05	92	147	5	20301317
Pubmed	Gut microbiota regulate hepatic von Willebrand factor synthesis and arterial thrombus formation via Toll-like receptor-2.	VWF TLR4	5.31e-05	3	147	2	28572286
Pubmed	Bacterial and host factors implicated in nasal carriage of methicillin-resistant Staphylococcus aureus in mice.	CFTR TLR4	5.31e-05	3	147	2	15731086
Pubmed	ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1.	EXO1 ATM	5.31e-05	3	147	2	26240375
Pubmed	ATM-mediated serine 72 phosphorylation stabilizes ribonucleotide reductase small subunit p53R2 protein against MDM2 to DNA damage.	RRM2B ATM	5.31e-05	3	147	2	19015526
Pubmed	Ezrin links CFTR to TLR4 signaling to orchestrate anti-bacterial immune response in macrophages.	CFTR TLR4	5.31e-05	3	147	2	28883468
Pubmed	Interferon-γ resets muscle cell fate by stimulating the sequential recruitment of JARID2 and PRC2 to promoters to repress myogenesis.	CIITA DMD	5.31e-05	3	147	2	24327761
Pubmed	EIF3D promotes gallbladder cancer development by stabilizing GRK2 kinase and activating PI3K-AKT signaling pathway.	GRK2 EIF3D	5.31e-05	3	147	2	28594409
Pubmed	Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.	UNC13C UNC13A	5.31e-05	3	147	2	33105896
Pubmed	TLR-induced PAI-2 expression suppresses IL-1β processing via increasing autophagy and NLRP3 degradation.	TLR4 SERPINB2	5.31e-05	3	147	2	24043792
Pubmed	The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.	UNC13C UNC13A	5.31e-05	3	147	2	23658173
Pubmed	Interactome analysis of the Tudor domain-containing protein SPF30 which associates with the MTR4-exosome RNA-decay machinery under the regulation of AAA-ATPase NVL2.	NVL MTREX	5.31e-05	3	147	2	33422691
Pubmed	Expression of transcription regulating genes in human preimplantation embryos.	POU3F1 POU6F1	5.31e-05	3	147	2	8567814
Pubmed	EphA2-YES1-ANXA2 pathway promotes gastric cancer progression and metastasis.	YES1 EPHA2	5.31e-05	3	147	2	33941853
Pubmed	Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.	UNC13C UNC13A	5.31e-05	3	147	2	15988013
Pubmed	The structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA binding.	RRM1 RRM2	5.31e-05	3	147	2	23519412
Pubmed	Molecular mechanisms of thioredoxin and glutaredoxin as hydrogen donors for Mammalian s phase ribonucleotide reductase.	RRM1 RRM2	5.31e-05	3	147	2	19176520
Pubmed	Effects of toll-like receptor-4 gene polymorphisms on soluble P-selectin and von Willebrand factor levels in hypercholesterolemic patients.	VWF TLR4	5.31e-05	3	147	2	17849054
Pubmed	The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs.	NVL MTREX	5.31e-05	3	147	2	31358741
Pubmed	Tumor BRCA1, RRM1 and RRM2 mRNA expression levels and clinical response to first-line gemcitabine plus docetaxel in non-small-cell lung cancer patients.	RRM1 RRM2	5.31e-05	3	147	2	19002265
GeneFamily	UNC13 homologs	UNC13C UNC13A	1.63e-04	4	95	2	836
GeneFamily	POU class homeoboxes and pseudogenes	POU3F1 POU3F2 POU6F1	2.31e-04	23	95	3	523
GeneFamily	EF-hand domain containing	CALB2 CETN1 RCN1 EFCAB3 DUOX1 PPP3R2	1.05e-03	219	95	6	863
GeneFamily	ATP binding cassette subfamily C	CFTR ABCC11	2.05e-03	13	95	2	807
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	CUL4B MYH10 DNAJC13 SETX RPAP3 VPS13C RRM2B ARFGEF1 XRCC4 ITPR2 PTPN13 RBM27 AKAP11 ATM MTREX ATP1B1 CSPP1 USP47	3.17e-08	656	147	18	M18979
Coexpression	VEGF_A_UP.V1_DN	DNAJC13 XRCC4 RRM2 YES1 MFAP3 PTPRE SERPINB2 EXO1 LRRC17	1.52e-06	193	147	9	M2675
ToppCell	LPS_only-Epithelial_alveolar-AT_2\|LPS_only / Treatment groups by lineage, cell group, cell type	DSP CFTR SEC11C BMP3 PTPN13 P4HB EPHA2 ATP1B1	3.23e-07	198	147	8	d087e738d69ca9853553fde46d4e7a8906439d32
ToppCell	Transverse-Dendritic_cell-cycling_DCs\|Transverse / Region, Cell class and subclass	MPEG1 RRM2 GASK1B ORC1 NEK2 TLR4 EXO1 DNASE1L3	3.48e-07	200	147	8	f588d8889f351c797963616a3575fa43efd46b9a
ToppCell	Transverse-(5)_Dendritic_cell-(52)_cycling_DCs\|Transverse / shred on region, Cell_type, and subtype	MPEG1 RRM2 GASK1B ORC1 NEK2 TLR4 EXO1 DNASE1L3	3.48e-07	200	147	8	51e643d48b5e97a0e117b578a6ea7d429c6cdd1e
ToppCell	mild_COVID-19_(asymptomatic)-T/NK_proliferative\|World / disease group, cell group and cell class (v2)	RGPD1 RRM1 RRM2 LCT ORC1 NEK2 EXO1	2.50e-06	182	147	7	9adf90bb2808f234d53b89ca0ae07380478204ad
ToppCell	mild_COVID-19_(asymptomatic)-T/NK_proliferative\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	RGPD1 RRM1 RRM2 LCT ORC1 NEK2 EXO1	2.59e-06	183	147	7	df8568751205313d149939ea2683097e3652a60b
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	DSP CFTR MYO5C ADK DUOX1 PTPN13 ATP1B1	2.78e-06	185	147	7	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFTR MYO5C ADK BMP3 DMD ATP1B1 AGBL1	2.88e-06	186	147	7	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	Healthy_donor-NK_CD56bright\|World / disease group, cell group and cell class (v2)	SPAG1 YES1 NLRP2 THEM4 PLXNA4 ADGRE5 ATM	3.09e-06	188	147	7	8ee359199c61c3b5b498ac35148390db5cc1a836
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	CFTR MYO5C ADK DUOX1 PTPN13 ATP1B1 AGBL1	3.43e-06	191	147	7	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYH10 MYO1E FREM1 ADK PTPN13 UNC13C TGS1	3.80e-06	194	147	7	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYH10 MYO1E FREM1 ADK PTPN13 UNC13C TGS1	3.80e-06	194	147	7	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DSP CFTR MYO5C BMP3 PTPN13 EPHA2 ATP1B1	4.21e-06	197	147	7	1485933986921ff45669d9b7501c8d17050b3e97
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DSP CFTR MYO5C BMP3 PTPN13 EPHA2 ATP1B1	4.35e-06	198	147	7	285f729140b1df029c24f6ca1d2438470ac51794
ToppCell	wk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_late\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DSP CFTR MYO5C ADK BMP3 DMD ATP1B1	4.35e-06	198	147	7	1851b7f4198b42c21c934e2fbda39dbd65e2625c
ToppCell	LPS_anti-TNF-Epithelial_alveolar\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DSP SEC11C MYO5C BMP3 PTPN13 P4HB ATP1B1	4.35e-06	198	147	7	53e9ed1b19cb26be58da0f37057caca0cdfaabeb
ToppCell	LPS_only-Epithelial_alveolar\|LPS_only / Treatment groups by lineage, cell group, cell type	DSP SEC11C MYO5C BMP3 PTPN13 EPHA2 ATP1B1	4.35e-06	198	147	7	655df75b9692d815c7f6910275e1f684ac63bf62
ToppCell	LPS_IL1RA-Epithelial_alveolar\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DSP SEC11C MYO5C BMP3 PTPN13 P4HB ATP1B1	4.50e-06	199	147	7	5b140ac88ebc25ce397ae577e48f3e271faf46e7
ToppCell	Megakaryocytic-erythropoietic-Erythro-cells-Polychromatic_Erythroblast\|Megakaryocytic-erythropoietic / Lineage, cell class and subclass	MYH10 RRM1 RRM2 ORC1 NEK2 EXO1 TGS1	4.50e-06	199	147	7	fa698f00d2dad74d28b4696c8c23dce70f123e52
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DSP CFTR MYO5C BMP3 PTPN13 EPHA2 ATP1B1	4.65e-06	200	147	7	e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	MYO1E NVL RRM1 RRM2 ORC1 GRK2 EXO1	4.65e-06	200	147	7	d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Stem_cells\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	BDH2 RCN1 RRM1 RRM2 PGM1 NEK2 LRRC17	4.65e-06	200	147	7	4c22a1f35ff496fa6af2ab171f2936785272bc06
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	MYO1E NVL RRM1 RRM2 ORC1 GRK2 EXO1	4.65e-06	200	147	7	3d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Stem_cells-Neuroepithelial_cell\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	BDH2 RCN1 RRM1 RRM2 PGM1 NEK2 LRRC17	4.65e-06	200	147	7	0632b8d3a1be437f146bc86aae9646303e37a0bd
ToppCell	(52)_cycling_DCs\|World / shred on Cell_type and subtype	MPEG1 RRM2 GASK1B ORC1 NEK2 TLR4 DNASE1L3	4.80e-06	201	147	7	ad2d25d84345fdd593065516a05c5c2b5429eac0
ToppCell	(24)_B_cell_cycling\|World / shred on Cell_type and subtype	MYO1E POU3F2 RRM2 ORC1 NEK2 EXO1 DMD	4.96e-06	202	147	7	a7c9b6b173701348ba35fbb975e0bdd3c1f1d5fe
ToppCell	LA-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	CYP8B1 MPEG1 LRRC8D SMARCE1 DMD MAPRE2	6.90e-06	139	147	6	9e2a84d5ed7232b70eadbba754d9ca13f2d50fe9
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D231\|Adult / Lineage, Cell type, age group and donor	MYH10 CCDC110 ARHGEF17 SERPINI1 DMD CDH13	1.43e-05	158	147	6	8d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCell	NS-control-d_0-4-Myeloid-pDC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MPEG1 ADA FMNL3 PTPRE PLXNA4 DNASE1L3	1.83e-05	165	147	6	8b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MPEG1 LRRC8D MOGS CHD5 TLR4 UNC13C	2.03e-05	168	147	6	a1755afa2cc50960ba60e07d84d61be429cdea72
ToppCell	metastatic_Brain-B_lymphocytes-GrB-secreting_B_cells\|metastatic_Brain / Location, Cell class and cell subclass	MPEG1 FMNL3 SERPINI1 PTPRE PLXNA4 DNASE1L3	2.10e-05	169	147	6	71f6761b9927f352e0ccc221ca373319915f4184
ToppCell	droplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 GASK1B OPHN1 EPHA2 SLC27A1 ATP1B1	2.24e-05	171	147	6	4e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCell	3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CALB2 CCDC110 FREM1 FMNL3 PLXNA4 ARHGEF6	2.24e-05	171	147	6	5885e69e997cc2f6a27afebfe57001ca0ac062a6
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP8B1 ORC1 NEK2 MOGS CIITA EXO1	2.64e-05	176	147	6	581045e61cdcdfa85701343d1a7c0a72a36606a7
ToppCell	B_cells-pDCs\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	MYO1E MPEG1 PTPRE EPHA2 PLXNA4 DNASE1L3	2.64e-05	176	147	6	ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ERCC4 RRM1 RRM2 RNF17 CHD5 TLR4	2.72e-05	177	147	6	1d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	OXR1 ABCA13 ARHGAP26 OPHN1 AGBL3 KCTD16	2.81e-05	178	147	6	c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-pDC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ADA PTPRE CIITA FCRL4 DNASE1L3	2.81e-05	178	147	6	b7d1d8f76c1c2467b1a39a9b4150ed4a47144a15
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MPEG1 ADA PTPRE CIITA PLXNA4 DNASE1L3	2.90e-05	179	147	6	c9f45cfea0ceb0cdc31bcfd123aeab69aeb35c35
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFTR SEC11C MYO5C BMP3 PTPN13 ATP1B1	2.99e-05	180	147	6	b798a3fa2dd15b68aa4267f665559527043dcc07
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYH10 MYO1E FREM1 OPHN1 PTPN13 DOCK7	3.18e-05	182	147	6	f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCell	(7)_DC_plasmacytoid\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	MPEG1 ADA PTPRE EPHA2 PLXNA4 DNASE1L3	3.28e-05	183	147	6	2c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	VWF ARHGAP26 FMNL3 PTPRE EXO1 DNASE1L3	3.38e-05	184	147	6	688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCell	droplet-Spleen-nan-21m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH10 REC114 MUC13 RRM1 RRM2 NEK2	3.48e-05	185	147	6	239cc5184825b3cc98638d4aec0a1de8e508d76c
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFTR SEC11C MYO5C BMP3 PTPN13 ATP1B1	3.48e-05	185	147	6	fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFTR SEC11C MYO5C BMP3 PTPN13 ATP1B1	3.48e-05	185	147	6	929b68b05b7686341329ac756d7df172cb4b810b
ToppCell	control-Myeloid-pDC\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MYO1E MPEG1 FMNL3 EPHA2 PLXNA4 DNASE1L3	3.59e-05	186	147	6	fe31e9cf4575ee40b50489593c51d8c36c3cc532
ToppCell	Multiple_Sclerosis-Myeloid-pDC\|Multiple_Sclerosis / Disease, Lineage and Cell Type	MYO1E MPEG1 PTPRE EPHA2 PLXNA4 DNASE1L3	3.59e-05	186	147	6	330a4f669adea91ff9f2dff2de2210f5e3401e19
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	VPS13C MPEG1 GASK1B GRK2 PTPRE DNAH8	3.59e-05	186	147	6	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA13 MYO5C ADK PTPN13 MTRR AGBL1	3.59e-05	186	147	6	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	CFTR MYO5C ADK PTPN13 ATP1B1 AGBL1	3.70e-05	187	147	6	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VWF ARHGAP26 FMNL3 SPTBN5 DNASE1L3 CDH13	3.70e-05	187	147	6	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	normal-na-Lymphocytic\|normal / PBMC cell types (v2) per disease, treatment status, and sex	RRM1 RRM2 LCT ORC1 NEK2 EXO1	3.93e-05	189	147	6	1d382f8eb998c6a30e09fddc9a427afc8f5f7323
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	VWF ARHGAP26 ITPR2 PLXNA4 UNC13C CDH13	3.93e-05	189	147	6	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	severe_COVID-19-Plasmablast\|severe_COVID-19 / disease group, cell group and cell class (v2)	CCDC110 SEC11C RRM2 ORC1 EXO1 UNC13C	3.93e-05	189	147	6	953143b2c2e87a4d8ef033a5fbb155fe62e9c78e
ToppCell	normal-na-Lymphocytic-lymphocyte\|normal / PBMC cell types (v2) per disease, treatment status, and sex	RRM1 RRM2 LCT ORC1 NEK2 EXO1	3.93e-05	189	147	6	b83fd81ecc5ef363be7435ee12cb7079e2434af7
ToppCell	normal-na-Lymphocytic-lymphocyte-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	RRM1 RRM2 LCT ORC1 NEK2 EXO1	3.93e-05	189	147	6	3db4177d68cab4cd16842d2ebcaca28f69300e44
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CFTR MYO5C ADK DUOX1 PTPN13 AGBL1	4.04e-05	190	147	6	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	COVID-19_Severe-pDC\|COVID-19_Severe / disease group, cell group and cell class	MYO1E MPEG1 ADA EPHA2 PLXNA4 DNASE1L3	4.04e-05	190	147	6	c5ab6b7492fb86aff3d2af3eb671c9f985ae4aeb
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFTR BMP3 PTPN13 EPHA2 MTRR AGBL1	4.16e-05	191	147	6	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	(01)_Dendritic_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	MYO1E CIITA EPHA2 PLXNA4 ATP1B1 DNASE1L3	4.16e-05	191	147	6	1f4c8078e1a6cd14937c714330af608caced2acf
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF MYO1E CASP10 FMNL3 CIITA CDH13	4.16e-05	191	147	6	a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	CFTR MYO5C ADK DUOX1 PTPN13 AGBL1	4.29e-05	192	147	6	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	CFTR MYO5C DUOX1 PTPN13 MTRR AGBL1	4.29e-05	192	147	6	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	ARHGAP26 ARFGEF1 AP1G1 ADGRE5 ATM MAPRE2	4.29e-05	192	147	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFTR MYO5C DUOX1 PTPN13 MTRR AGBL1	4.29e-05	192	147	6	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	control-pDC\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MYO1E ADA PTPRE EPHA2 PLXNA4 DNASE1L3	4.41e-05	193	147	6	30a6559c9a9e8941861cb259b4836acccc427e68
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFTR MYO5C ADK PTPN13 ATP1B1 AGBL1	4.41e-05	193	147	6	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	Control-Lymphoid-pDC\|Lymphoid / Condition, Lineage and Cell class	MPEG1 CIITA EPHA2 CYP2U1 DMD DNASE1L3	4.54e-05	194	147	6	5f95a5a35f73222dbe2ca52cc580f4774f641403
ToppCell	moderate-Epithelial-FOXN4+\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SPAG1 ABCA13 MYO5C NEK2 DUOX1 CSPP1	4.54e-05	194	147	6	5dffa578149104dda33774361e9e77b227b5f1ce
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH10 RCN1 RRM1 RRM2 FREM1 ADK	4.54e-05	194	147	6	af4bbb2deb5a3913eb58990690fc3c62fbc3708c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	VWF ARHGAP26 ADA YES1 PTPRE DNASE1L3	4.67e-05	195	147	6	818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCell	Control-Classical_Monocyte-cMono_2\|Control / Disease condition and Cell class	ARHGAP26 MPEG1 GASK1B GRK2 PTPRE TLR4	4.67e-05	195	147	6	0fea64ee3eedf3929abb0dd9c5f5fc72f181eed9
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIK1 FREM1 BMP3 UNC13C FCRL4 CDH13	4.67e-05	195	147	6	98ca9f3aa36211dde1e6f7f3817b9418c95e583e
ToppCell	wk_20-22-Epithelial-Distal_epithelial-type_I_pneumocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DSP CFTR MYO5C ADK MLXIPL DMD	4.81e-05	196	147	6	e24a7aaf41793abba66c1189d933ca05b14c1af9
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MPEG1 FMNL3 PTPRE CIITA PLXNA4 DNASE1L3	4.81e-05	196	147	6	787088ce800d7148bad7265a971797da597b029a
ToppCell	distal-3-Hematologic-Plasmacytoid_Dendritic\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MPEG1 ADA PTPRE EPHA2 PLXNA4 DNASE1L3	4.81e-05	196	147	6	6028b790abba9bad1d5373bab13eb24855988f48
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PNLIPRP1 DSP VPS13C MYO5C AOPEP ATP1B1	4.95e-05	197	147	6	b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ITPR2 PTPRE CIITA TLR4 DNASE1L3	4.95e-05	197	147	6	10190b877bf46ba2163d203df9dd3b498c66e52f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VWF GASK1B FMNL3 CIITA DNASE1L3 CDH13	4.95e-05	197	147	6	cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DSP CCDC110 MYO5C BMP3 PTPN13 ATP1B1	4.95e-05	197	147	6	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	CFTR MYO5C BMP3 PTPN13 EPHA2 ATP1B1	4.95e-05	197	147	6	1a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VWF GASK1B FMNL3 PTPRE CIITA DNASE1L3	4.95e-05	197	147	6	412cb5f37df57121ddd1492021445479c7cbccbf
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ITPR2 PTPRE CIITA TLR4 DNASE1L3	5.09e-05	198	147	6	dbae6a58cb3ce8612755fbdba6194b70b35f258a
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFTR MYO5C DUOX1 PTPN13 MTRR AGBL1	5.09e-05	198	147	6	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-Macrophages\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ITPR2 PTPRE CIITA TLR4 DNASE1L3	5.09e-05	198	147	6	88635244a0b306d2cc50b8412fe47bb359c9cf00
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	OPHN1 ADK PTPN13 AOPEP DMD AGBL1	5.09e-05	198	147	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2-AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SEC11C BMP3 PTPN13 P4HB EPHA2 ATP1B1	5.09e-05	198	147	6	d499dced27b0c0e21acfda2c20fa5c114f605085
ToppCell	distal-1-Hematologic-Proliferating_Macrophage\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	POU3F2 RRM1 RRM2 ORC1 NEK2 EXO1	5.09e-05	198	147	6	df3f5559ecd1f3cd1fd60e39dbad8741309e83a3
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SEC11C BMP3 PTPN13 P4HB EPHA2 ATP1B1	5.09e-05	198	147	6	aa80315395cb5dffc25927c8a77cd2037aea8772
ToppCell	distal-Hematologic-Proliferating_Macrophage-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	POU3F2 RRM1 RRM2 ORC1 NEK2 EXO1	5.09e-05	198	147	6	2b0716e900bce54ad1825d6dcdaf4ebf31f355c4
ToppCell	wk_15-18-Epithelial-Airway_epithelial_progenitor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DSP CFTR MYO5C ADK BMP3 DMD	5.09e-05	198	147	6	c477405b093f4e5374e57bcacf1fb204a0f7eb3b
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-2_Progenitor-AT2_Progenitor\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DSP SEC11C MYO5C PTPN13 P4HB ATP1B1	5.09e-05	198	147	6	82bcd44f8744e7e8477fbfd871a52f3d1a8b3adc
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DSP ABCA13 CFTR DUOX1 PTPN13 EPHA2	5.09e-05	198	147	6	19d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCell	MS-Multiple_Sclerosis-Myeloid-pDC\|Multiple_Sclerosis / Disease, condition lineage and cell class	MYO1E MPEG1 ADA PTPRE PLXNA4 DNASE1L3	5.23e-05	199	147	6	c10c8c9322cad4996e4aa11a8680e3d781644ace
ToppCell	MS-IIF-Myeloid-pDC\|IIF / Disease, condition lineage and cell class	MYO1E MPEG1 FMNL3 PTPRE PLXNA4 DNASE1L3	5.23e-05	199	147	6	e262ee854e64d87460bee810c14d6cbe744460e8
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	SPAG1 SETX VPS13C EPHA2 SMARCE1 CSPP1	5.23e-05	199	147	6	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYO5C ADK DUOX1 PTPN13 PTPRE AGBL1	5.23e-05	199	147	6	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPEG1 ITPR2 PTPRE CIITA TLR4 DNASE1L3	5.23e-05	199	147	6	f34c15df58fbdc6c90e30800e26fabbf828ad10b
ToppCell	(2)_B_cell-(24)_B_cell_cycling\|(2)_B_cell / shred on Cell_type and subtype	POU3F2 RRM1 RRM2 ORC1 NEK2 EXO1	5.23e-05	199	147	6	d5a9a8a71c4de8cbcef947943f60838731bc640b
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	MYO1E NVL RRM1 RRM2 GRK2 EXO1	5.23e-05	199	147	6	fd1d1b95e01719e3d0a17d9d1f29717a47209d32
Computational	Genes in the cancer module 219.	RRM1 RRM2 ADA ADK	5.07e-05	27	83	4	MODULE_219
Drug	mdGuo	RRM2B RRM1 RRM2 ADK	7.64e-09	5	144	4	CID000126596
Drug	MdAdo	RRM2B RRM1 RRM2 ADK	7.64e-09	5	144	4	CID000175972
Drug	Adenosine phosphonoacetic acid	RRM2B RRM1 RRM2	2.48e-07	3	144	3	CID000448505
Drug	2'-deoxytoyocamycin	RRM2B RRM1 RRM2	2.48e-07	3	144	3	CID000204132
Drug	1-amino-3-hydroxyguanidine	RRM2B RRM1 RRM2	2.48e-07	3	144	3	CID009571038
Drug	Bild 1351	RRM2B RRM1 RRM2	2.48e-07	3	144	3	CID005478827
Drug	hydroxyguanidine sulfate	RRM2B RRM1 RRM2	2.48e-07	3	144	3	CID000080667
Drug	cyclo(Sar-Sar	RRM2B RRM1 RRM2	2.48e-07	3	144	3	CID000078761
Drug	AC1N8OVF	RRM2B RRM1 RRM2	2.48e-07	3	144	3	CID004347182
Drug	2'-chloro-2'-dudp	RRM2B RRM1 RRM2	2.48e-07	3	144	3	CID003082518
Drug	3,4-dihydroxybenzaldoxime	RRM2B RRM1 RRM2	2.48e-07	3	144	3	CID005388593
Drug	NSC-137029	RRM2B RRM1 RRM2	2.48e-07	3	144	3	CID000421633
Drug	Bild 1357	RRM2B RRM1 RRM2	2.48e-07	3	144	3	CID000515298
Drug	2'-azido-2'-deoxycytidine 5'-diphosphate	RRM2B RRM1 RRM2	2.48e-07	3	144	3	CID000170963
Drug	AC1LAKEY	RRM2B RRM1 RRM2	2.48e-07	3	144	3	CID000515340
Drug	Val-Val-Asn-Asp-Leu	RRM2B RRM1 RRM2	2.48e-07	3	144	3	CID000515343
Drug	dial-CDP	RRM2B RRM1 RRM2	2.48e-07	3	144	3	CID005487791
Drug	IMPY	DSP RRM2B RRM1 RRM2	4.89e-07	11	144	4	CID005356114
Drug	2-formylpyridine thiosemicarbazonato copper(II	RRM2B RRM1 RRM2	9.87e-07	4	144	3	CID009576822
Drug	4-nitro-benzohydrazide	RRM2B RRM1 RRM2	9.87e-07	4	144	3	CID003693744
Drug	p-propoxyphenol	RRM2B RRM1 RRM2	9.87e-07	4	144	3	CID000029352
Drug	Dacisteine	RRM2B RRM1 RRM2	9.87e-07	4	144	3	CID000065690
Drug	BPYTA	RRM2B RRM1 RRM2	9.87e-07	4	144	3	CID003034633
Drug	2-formylpyridine thiosemicarbazone	RRM2B RRM1 RRM2	9.87e-07	4	144	3	CID001638752
Drug	2'-azido-2'-deoxyuridine	RRM2B RRM1 RRM2	9.87e-07	4	144	3	CID000168629
Drug	N6-benzyladenosine	GAK RRM1 RRM2 ADA ADK	1.94e-06	33	144	5	CID000092208
Drug	DMDC	RRM2B HMOX2 RRM1 RRM2	1.98e-06	15	144	4	CID000119360
Drug	A1110U	RRM2B RRM1 RRM2	2.45e-06	5	144	3	CID003006964
Drug	2-methylene-3-furanone	RRM2B RRM1 RRM2	2.45e-06	5	144	3	CID000124504
Drug	348U87	RRM2B RRM1 RRM2	2.45e-06	5	144	3	CID003006985
Drug	AC1NQVLK	RRM2B RRM1 RRM2	2.45e-06	5	144	3	CID002732427
Drug	2-hydroxy-1-naphthylaldehyde benzoyl hydrazone	RRM2B RRM1 RRM2	2.45e-06	5	144	3	CID005384003
Drug	p-butoxyphenol	RRM2B RRM1 RRM2	2.45e-06	5	144	3	CID000031233
Drug	bruceine	RRM2B RRM1 RRM2	2.45e-06	5	144	3	CID000122785
Drug	N-hydroxy-N'-methylurea	RRM2B RRM1 RRM2	2.45e-06	5	144	3	CID000096412
Drug	Citrusinine-I	RRM2B RRM1 RRM2	2.45e-06	5	144	3	CID005487772
Drug	2',2'-difluorodeoxyguanosine	RRM2B RRM1 RRM2 ADK	3.43e-06	17	144	4	CID000147055
Drug	8-aminoguanosine	RRM2B RRM1 RRM2 ADA ADK	4.00e-06	38	144	5	CID000096849
Drug	8-cyclopentyltheophylline	CFTR GRIK1 ADA ADK MTRR	4.00e-06	38	144	5	CID000001917
Drug	3-acetylisoquinoline	RRM2B GRIK1 RRM1	4.89e-06	6	144	3	CID000124656
Drug	VF 122	RRM2B RRM1 RRM2	4.89e-06	6	144	3	CID000100590
Drug	2-deoxy-D-ribose-1-phosphate	RRM1 RRM2 ADA PGM1 ADK	7.49e-06	43	144	5	CID000000634
Drug	glutathione reduced	RRM2B CFTR NAPA ABCC11 CASP10 HMOX2 RRM1 RRM2 PPP3R2 MOGS AP1G1 P4HB ABCB11 ADGRE5	7.79e-06	534	144	14	CID000000745
Drug	Thioredoxin Sulfide	RRM2B RRM1 RRM2 P4HB MTRR	9.41e-06	45	144	5	CID006857408
Drug	NSC89222	RRM2B RRM1 RRM2 ADA ADK	1.17e-05	47	144	5	CID000000142
Drug	S-adenosyl-D-homocysteine	RRM2B XRCC4 RRM1 RRM2 ADA ADK TCERG1 MTRR TGS1	1.23e-05	222	144	9	CID000000193
Drug	parabactin	RRM2B RRM1 RRM2	1.36e-05	8	144	3	CID005487017
Drug	B Hm	RRM2B RRM1 RRM2	1.36e-05	8	144	3	CID000100038
Drug	GC Q	RRM2B RRM1 RRM2	1.36e-05	8	144	3	CID006420157
Drug	AC1MHU3O	RRM2B RRM1 RRM2	1.36e-05	8	144	3	CID003032423
Drug	N3UDP	RRM2B RRM1 RRM2	1.36e-05	8	144	3	CID000169817
Drug	AC1Q6S1T	RRM2B RRM1 RRM2 ADK DMD	1.44e-05	49	144	5	CID000000644
Drug	EHNA	RRM2B RRM1 RRM2 ADA ADK TGS1	1.91e-05	87	144	6	CID000003206
Drug	adenosylcobalamin	RRM2B RRM1 RRM2 PGM1 MTRR	2.12e-05	53	144	5	CID000424379
Drug	glycyl radical	RRM2B RRM1 RRM2 ADK	2.79e-05	28	144	4	CID005460845
Drug	ferrous ammonium sulfate	RRM2B HMOX2 RRM1 RRM2	2.79e-05	28	144	4	CID000024863
Drug	2'-deoxytetrahydrouridine	RRM2B RRM1 RRM2	2.88e-05	10	144	3	CID000161730
Drug	cystein-S-yl	RRM2B RRM1 RRM2	2.88e-05	10	144	3	CID005360637
Drug	guanazole	RRM2B RRM1 RRM2	2.88e-05	10	144	3	CID000015078
Drug	AC1O592B	RRM2B RRM1 RRM2	2.88e-05	10	144	3	CID006480203
Drug	Leflunomide [75706-12-6]; Up 200; 14.8uM; PC3; HT_HG-U133A	KERA POU3F2 HMOX2 XRCC4 GASK1B MFAP3L SPTBN5 CA5B	3.49e-05	195	144	8	5884_UP
Drug	Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; MCF7; HT_HG-U133A	MIIP MYO1E POU6F1 AAGAB MFAP3L MFAP3 MAPRE2 LRRC17	3.62e-05	196	144	8	1494_UP
Drug	Cytisine (-) [485-35-8]; Down 200; 21uM; HL60; HG-U133A	CUL4B SETX CETN1 ARFGEF1 HMOX2 PRCC ADGRE5 ATM	3.89e-05	198	144	8	1766_DN
Drug	HPOs	RRM2B RRM1 RRM2	3.94e-05	11	144	3	CID003080643
Drug	AC1L2O7O	RRM2B RRM1	3.97e-05	2	144	2	CID000075180
Drug	benzyl-beta-lactoside	CFTR LCT	3.97e-05	2	144	2	CID003462525
Drug	tris(tetrabutylammonium) hydrogen pyrophosphate	RRM2B RRM1	3.97e-05	2	144	2	CID011115639
Drug	2-amino-1-hydroxyguanidine	RRM2B RRM1	3.97e-05	2	144	2	CID005464082
Drug	NBDI	CFTR SERPINB2	3.97e-05	2	144	2	CID000076317
Drug	SureCN843110	RRM2B RRM1	3.97e-05	2	144	2	CID014570995
Drug	v 1394	RRM2B RRM1	3.97e-05	2	144	2	CID000101484
Drug	2'-MeUDP	RRM1 RRM2	3.97e-05	2	144	2	CID000192502
Drug	NSC351140	ERCC4 RRM2B RRM1 RRM2 NLRP2 ORC1 NEK2 PRCC ATM	4.03e-05	258	144	9	CID000002210
Drug	Demecolcine	ARHGAP26 RRM2B RRM2 ZBTB24 PGM1 ORC1 GPBP1L1 SERPINI1 TLR4 SERPINB2 EXO1 ADGRE5 UNC13C FCRL4 DMD DNASE1L3 ARHGEF6	4.16e-05	878	144	17	ctd:D003703
Drug	1-o-phosphonopentofuranose	RRM2B RRM1 RRM2 ADA PGM1	4.22e-05	61	144	5	CID000001074
Drug	cresyl violet acetate	FLII CALB2 GRIK1 FGF17 SERPINB2	4.22e-05	61	144	5	CID000082686
Drug	AC1NBT2J	RRM2B RRM1 RRM2 MTRR	4.81e-05	32	144	4	CID003958805
Drug	AC1Q6S1V	RRM2B RRM1 RRM2 ADA ADK	4.94e-05	63	144	5	CID000000620
Drug	2-fluoroadenine arabinoside	VWF RRM2B ABCC11 RRM1 RRM2 ADK ATM	6.73e-05	158	144	7	CID000003367
Drug	Anhydrous	RRM2B RRM1 RRM2	6.76e-05	13	144	3	CID006435808
Drug	AC1NTMU5	RRM2B RRM1 RRM2	6.76e-05	13	144	3	CID003035508
Drug	dipyridamole	VWF RRM2B RRM1 RRM2 ADA ADK GRK2	7.88e-05	162	144	7	CID000003108
Drug	HPMPApp	RRM2B RRM1 RRM2	8.57e-05	14	144	3	CID000506018
Drug	Ta 3	RRM2B RRM1 RRM2	8.57e-05	14	144	3	CID000027110
Drug	NSC-218321	RRM2B RRM1 RRM2 ADA ADK DUOX1	8.78e-05	114	144	6	CID000004739
Drug	methyl methanesulfonate	ERCC4 RRM2B ARFGEF1 XRCC4 RRM1 RRM2 ADA NLRP2 EXO1 ATM	1.11e-04	364	144	10	CID000004156
Drug	AC1Q6S1O	RRM2B RRM1 RRM2 ADK	1.18e-04	40	144	4	CID000000623
Drug	beta-dimethylaminopropiophenone	RRM2B RRM1	1.19e-04	3	144	2	CID000077042
Drug	2D ABR	RRM2B RRM1	1.19e-04	3	144	2	CID000125209
Drug	6-aminothymine	RRM2B RRM1	1.19e-04	3	144	2	CID000065245
Drug	In 285	PGM1 ADK	1.19e-04	3	144	2	CID000046731
Drug	3'-C-methyluridine	RRM1 RRM2	1.19e-04	3	144	2	CID005270589
Drug	2,4-dihydroxyphenylacetic acid	GRIK1 YES1	1.19e-04	3	144	2	CID000069199
Drug	L-methionine sulfoxide	RRM2B HMOX2 RRM1 RRM2 MTRR	1.29e-04	77	144	5	CID000000847
Drug	caracemide	RRM2B RRM1 RRM2	1.31e-04	16	144	3	CID000054747
Drug	AC1MHKBU	RRM2B RRM1 RRM2	1.31e-04	16	144	3	CID003006315
Drug	irinotecan	MYH10 CFTR XRCC4 ADA YES1 OPHN1 ADK ORC1 MLXIPL NEK2 PTPN13 THEM4 TLR4 ATM	1.54e-04	703	144	14	ctd:C051890
Drug	gallium	RRM2B HMOX2 RRM1 RRM2 DMD	1.55e-04	80	144	5	CID000105145
Drug	phosphoramide mustard	CFTR TLR4 EXO1 ATM	1.56e-04	43	144	4	ctd:C030090
Drug	sebacate	ERCC4 ARFGEF1 XRCC4 LCT NLRP2 EXO1 ATM	1.57e-04	181	144	7	CID000005192
Disease	Colorectal Carcinoma	ABCA13 CFTR RCN1 ARFGEF1 RRM2 PGM1 CHD5 TLR4 EXO1 ABCB11 MTRR DMD DNAH8 DNASE1L3 ZMYM4	2.09e-06	702	145	15	C0009402
Disease	egg allergy measurement	ERCC4 SERPINB2 ABCB11	9.55e-06	9	145	3	EFO_0007018
Disease	Colorectal Neoplasms	ABCA13 CFTR RRM2 PGM1 CHD5 TLR4 EXO1 ABCB11 MTRR	9.91e-06	277	145	9	C0009404
Disease	Liver carcinoma	RRM1 RRM2 ORC1 MLXIPL NEK2 THEM4 TLR4 EXO1 ATM DNASE1L3 CDH13	4.42e-05	507	145	11	C2239176
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	XRCC4 EXO1 ATM	1.06e-04	19	145	3	C1333991
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	XRCC4 EXO1 ATM	1.06e-04	19	145	3	C2936783
Disease	X-linked mental retardation with cerebellar hypoplasia and distinctive facial appearance (implicated_via_orthology)	ARHGAP26 OPHN1	1.43e-04	4	145	2	DOID:0080311 (implicated_via_orthology)
Disease	FANCONI ANEMIA, COMPLEMENTATION GROUP Q	ERCC4 XRCC4	1.43e-04	4	145	2	C3808988
Disease	neutrophil count	DNAJC13 OXR1 MYO1E CYP8B1 ARHGAP26 PCDHA1 LCT ITPR2 MLXIPL THEM4 PRCC AKAP11 UNC13C ATP1B1 MAPRE2 ZMYM4 USP47 TGS1	1.56e-04	1382	145	18	EFO_0004833
Disease	pancreatic cancer (is_implicated_in)	ERCC4 CFTR RRM2 MTRR ATM	2.35e-04	112	145	5	DOID:1793 (is_implicated_in)
Disease	fasting blood glucose measurement, glucose tolerance test, fasting blood insulin measurement	VPS13C ABCB11	2.38e-04	5	145	2	EFO_0004307, EFO_0004465, EFO_0004466
Disease	Dwarfism	ERCC4 XRCC4 ORC1	2.47e-04	25	145	3	C0013336
Disease	Drug habituation	CFTR MYO5C ATP1B1 DNAH8 CDH13	2.66e-04	115	145	5	C0013170
Disease	Drug abuse	CFTR MYO5C ATP1B1 DNAH8 CDH13	2.66e-04	115	145	5	C0013146
Disease	Prescription Drug Abuse	CFTR MYO5C ATP1B1 DNAH8 CDH13	2.66e-04	115	145	5	C4316881
Disease	Substance-Related Disorders	CFTR MYO5C ATP1B1 DNAH8 CDH13	2.66e-04	115	145	5	C0236969
Disease	Drug Use Disorders	CFTR MYO5C ATP1B1 DNAH8 CDH13	2.66e-04	115	145	5	C0013222
Disease	Drug Dependence	CFTR MYO5C ATP1B1 DNAH8 CDH13	2.66e-04	115	145	5	C1510472
Disease	Substance Dependence	CFTR MYO5C ATP1B1 DNAH8 CDH13	2.66e-04	115	145	5	C0038580
Disease	Substance Use Disorders	CFTR MYO5C ATP1B1 DNAH8 CDH13	2.66e-04	115	145	5	C0038586
Disease	Organic Mental Disorders, Substance-Induced	CFTR MYO5C ATP1B1 DNAH8 CDH13	2.66e-04	115	145	5	C0029231
Disease	Substance abuse problem	CFTR MYO5C ATP1B1 DNAH8 CDH13	2.77e-04	116	145	5	C0740858
Disease	Hereditary Nonpolyposis Colorectal Neoplasms	XRCC4 EXO1 ATM	2.78e-04	26	145	3	C0009405
Disease	Hereditary non-polyposis colorectal cancer syndrome	XRCC4 EXO1 ATM	3.12e-04	27	145	3	C1112155
Disease	level of Phosphatidylcholine (18:2_18:2) in blood serum	DOCK7 PLXNA4	3.55e-04	6	145	2	OBA_2045106
Disease	meningioma (is_implicated_in)	MTRR SMARCE1	3.55e-04	6	145	2	DOID:3565 (is_implicated_in)
Disease	Hereditary Nonpolyposis Colorectal Cancer	XRCC4 EXO1 ATM	3.87e-04	29	145	3	C1333990
Disease	abdominal fat cell number	DNAJC13 MYO1E RPAP3 MANEA FMNL3 TCERG1	4.54e-04	198	145	6	EFO_0021534
Disease	cystic fibrosis (implicated_via_orthology)	CFTR ABCB11	8.44e-04	9	145	2	DOID:1485 (implicated_via_orthology)
Disease	PITUITARY DWARFISM I	ERCC4 XRCC4	8.44e-04	9	145	2	C0342573
Disease	Congenital disorder of glycosylation	PGM1 MOGS RFT1	8.64e-04	38	145	3	cv:C0282577
Disease	pleural tuberculosis (is_marker_for)	ADA TLR4	1.05e-03	10	145	2	DOID:106 (is_marker_for)
Disease	Paranoia	MANEA DNAH8	1.28e-03	11	145	2	C1456784
Disease	response to virus	POU3F2 AGBL1	1.28e-03	11	145	2	GO_0009615
Disease	body surface area	EEF1AKMT4-ECE2 ARHGAP26 RGPD1 KERA SEC11C RRM2 ZBTB24 MFAP3 AOPEP CDH13	1.34e-03	643	145	10	EFO_0022196
Disease	ficolin-3 measurement	MAPRE2 DNASE1L3	1.53e-03	12	145	2	EFO_0020392
Disease	cardiovascular disease	YES1 AAGAB FREM1 ADK SPTBN5 EPHA2 DOCK7 SMARCE1	1.96e-03	457	145	8	EFO_0000319
Disease	factor VIII measurement, coronary artery disease	VWF ARHGAP26 ATP1B1 MAPRE2	2.38e-03	113	145	4	EFO_0001645, EFO_0004630
Disease	glucose homeostasis measurement, glucose effectiveness measurement	MYO5C CDH13	2.41e-03	15	145	2	EFO_0006833, EFO_0006896
Disease	Proteinuria	VWF UNC13C	2.41e-03	15	145	2	HP_0000093
Disease	Benign neoplasm of stomach	CASP10 ATM	3.11e-03	17	145	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	CASP10 ATM	3.11e-03	17	145	2	C0496905
Disease	Carcinoma in situ of stomach	CASP10 ATM	3.11e-03	17	145	2	C0154060
Disease	non-Hodgkin lymphoma (is_implicated_in)	CASP10 MTRR	3.11e-03	17	145	2	DOID:0060060 (is_implicated_in)
Disease	protein-glutamine gamma-glutamyltransferase e measurement	MLXIPL ABCB11 MAPRE2	3.24e-03	60	145	3	EFO_0020690
Disease	alcohol consumption measurement	EEF1AKMT4-ECE2 MYH10 ERCC4 SPTBN5 MLXIPL AP1G1 RBM27 PRCC PLXNA4 AKAP11 MAPRE2 AGBL1 STK24 CDH13	3.30e-03	1242	145	14	EFO_0007878
Disease	oral squamous cell carcinoma (is_marker_for)	ADA PTPN13 ATM	3.72e-03	63	145	3	DOID:0050866 (is_marker_for)
Disease	serum dimethylarginine measurement	MANEA PTPN13 CDH13	3.72e-03	63	145	3	EFO_0005418
Disease	Chronic myeloproliferative disorder	XRCC4 ORC1	3.88e-03	19	145	2	C1292778
Disease	diet measurement, HOMA-B	PLXNA4 CDH13	3.88e-03	19	145	2	EFO_0004469, EFO_0008111
Disease	familial hyperlipidemia (biomarker_via_orthology)	ADA SLC27A1	3.88e-03	19	145	2	DOID:1168 (biomarker_via_orthology)
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	CYP8B1 MLXIPL TLR4	4.06e-03	65	145	3	DOID:0080208 (biomarker_via_orthology)
Disease	X-24309 measurement	DNAJC13 FBF1	4.30e-03	20	145	2	EFO_0800872
Disease	left atrial function	DSP AOPEP	4.74e-03	21	145	2	EFO_0004294
Disease	Stomach Carcinoma	CASP10 ATM	4.74e-03	21	145	2	C0699791
Disease	susceptibility to mononucleosis measurement	MANEA DMD DNAH8	4.81e-03	69	145	3	EFO_0008403

Protein segments in the cluster

Peptide	Gene	Start	Entry
SNFGKERFVKLLDQL	UNC13A	926	Q9UPW8
LRKAKENEEFLIGFN	BMP3	206	P12645
FEARFESGNLQKVVK	AGBL3	171	Q8NEM8
GFTEEEFKRLNINAA	ADA	316	P00813
QFRTLLFTSEGEKEK	CA5B	261	Q9Y2D0
SEKDRFQGRFDVKIE	ATP1B1	286	P05026
TFAREQGFETKDIKE	ADK	246	P55263
KARFNFKQTNEDELS	ARHGEF6	166	Q15052
QKVFIFSGTFRKNLD	CFTR	1291	P13569
SFEDNAIRSGKKVFR	CHD5	796	Q8TDI0
FQDSQLEGLSKDIFK	CIITA	106	P33076
FLEKGELANFRFQKD	ARFGEF1	1221	Q9Y6D6
ITFNKTNGLRKDFDL	GRIK1	376	P39086
GDENDVFRSNFKIIK	FCRL4	171	Q96PJ5
SRFFDKVQDLGRDSK	ADGRE5	276	P48960
LLGKNTFEFLKENNF	CLK3	386	P49761
NSLFDKNFRSESVKL	ABCA13	3466	Q86UQ4
ILRSIKKFGEENDGF	ABCB11	6	O95342
DLVEKSFGSAFKDLQ	AKAP11	556	Q9UKA4
QFSVKGDEEQKLRFA	PPP3R2	81	Q96LZ3
FLEDGNRFKKQNSSI	AOPEP	46	Q8N6M6
SIFKNNEISFKLGEE	FABP12	56	A6NFH5
EFAIFRKEGNFSDLK	DMD	746	P11532
DIQGSLQDIFKFART	CDH13	116	P55290
KFFTSVKEIRGQFEE	CCDC180	1471	Q9P1Z9
EQKERELKGSFIRFD	CFAP73	71	A6NFT4
ELKGSFIRFDKFLQD	CFAP73	76	A6NFT4
RLEKLNKGEGFSDQF	DENND1C	391	Q8IV53
QEKGRKIAAFFAESL	PHYKPL	201	Q8IUZ5
FFSKFESGNLRKAIQ	AGBL1	596	Q96MI9
NLRGDVFQKFIESDK	GRK2	156	P25098
NKFAKLIVETDTFGS	FGF17	81	O60258
DRSFVGKQFSANDKV	PGM1	451	P36871
QFNEFRDLNKDGKLD	RCN1	251	Q15293
LFRVQFSGESKEQAL	REC114	116	Q7Z4M0
FLQKETSGFVDKLFE	RBM27	56	Q9P2N5
FFKQSFLKQILTEGE	RFT1	246	Q96AA3
LENFRKEQIGFTKER	OPHN1	116	O60890
KARGLEFQISNVKFE	NVL	251	O15381
GLERDKFDNKTVSFE	ITPR2	2566	Q14571
LFSKVNGKFSTEFQR	MPEG1	121	Q2M385
GFEQAFDEAKRKLAS	ARHGEF17	1461	Q96PE2
SKNGLKIEFTFERSN	AP1G1	711	O43747
FENTRNGLFSKKEIE	DUOX1	516	Q9NRD9
FDKIGLEEEFRKLTN	PTPRE	421	P23469
KTEKAINEFFRTEGA	MFAP3L	181	O75121
INEFFRTEGAEKLQK	MFAP3L	186	O75121
RSLEGTEAQVFKAKF	FLII	821	Q13045
FTAFSQKELAGKIRE	NEK2	216	P51955
TANDLAKDSKGRFFI	KCTD16	61	Q68DU8
LKTLKDDRNGDFSEN	GPBP1L1	326	Q9HC44
EISKIESEAFFGLNK	LRRC17	116	Q8N6Y2
FDDSGRKDSEVLKQN	MTRR	196	Q9UBK8
FFDLNEKQGRKRSST	CWF19L1	291	Q69YN2
ETLQKAGFSEKFLNE	PCYOX1	201	Q9UHG3
DDDLLFTVFSKGQKR	PLXNA4	331	Q9HCM2
KFAGRTSEEQQKFFL	PNLIPRP1	331	P54315
FFNLNEKTGEITTKD	PCDHGB2	291	Q9Y5G2
FLRGKEESSEKFRQV	CSPP1	186	Q1MSJ5
DNVLEKNFIKSGTTF	DNAH8	3526	Q96JB1
LIDRGFSKDFSENKQ	FREM1	1196	Q5H8C1
GKTEDFISQFKRLTD	ABCC11	1016	Q96J66
SSDDLEQFAKQFKQR	POU3F1	251	Q03052
GINLEEIREFAKNFK	POU6F1	141	Q14863
FTEAEKQLLKGSADF	LCT	666	P09848
RFKTEAQAFTETKGN	NLRP2	126	Q9NX02
TDNQRILEFFGLKKE	P4HB	296	P07237
DRAENTQFVKDFLKG	HMOX2	46	P30519
GKNFDFQKSDRINSE	MANEA	56	Q5SRI9
EKAINEFFRTEGAEK	MFAP3	181	P55082
EFFRTEGAEKLQKAF	MFAP3	186	P55082
FKENIQDLVFRTKTG	MED14	591	O60244
EGFRERFEKTFQLKE	MOGS	366	Q13724
FDSGISRDIQEKFKV	PCDHA1	281	Q9Y5I3
TFGNRTLSKKEDFFI	OXR1	851	Q8N573
RFLGNSKSDQEEKEI	ORC1	396	Q13415
RFLDDQGQLIKKETF	CYP2U1	466	Q7Z449
KGFFDRSEDNLNFKL	GASK1B	431	Q6UWH4
FSSREEQQDILSKFG	GAK	736	O14976
GSLFVKATFDRQSKE	EEF1AKMT4-ECE2	561	P0DPD8
TLFKNKTNEEFRIGS	ATM	761	Q13315
LENEQFFLETLKKGS	FBF1	1111	Q8TES7
FNVRSFGESKQEDKN	DNASE1L3	26	Q13609
TLTVTNFFKQEGDRL	DOCK7	466	Q96N67
DKFLREKDGEFSVLQ	EPHA2	701	P29317
EFTKLGLEEFLQKSR	FMNL3	346	Q8IVF7
RVGSKLFFDKRDNSD	EIF3D	271	O15371
GDDDKRKIQSQFTDA	DSP	601	P15924
AFKSEETKGQDIFQR	DNAJC13	1151	O75165
VEKLVKGRFQDNLDF	MAPRE2	136	Q15555
SFLAFLEKQGKIDED	CASP10	151	Q92851
LENFFQELEKARKGS	CALB2	41	P22676
DIDRDGKVNFSDFIK	EFCAB3	96	Q8N7B9
QKKLRFEDTLEFVGF	CUL4B	116	Q13620
FGNISFKKERNTDQA	MYH10	356	P35580
LGEARLETKQSFAFK	CYP8B1	316	Q9UNU6
LFGSDFEKEKQQRNA	IRF2BP1	191	Q8IU81
SKRFGVFLSEVSENK	LRRC8D	431	Q7L1W4
EENTFEVKLFKNSSG	PTPN13	1496	Q12923
SQGVKLFRFDAEISQ	RGPD1	1046	P0DJD0
LKNGEEFSFLKEFSN	SERPINI1	81	Q99574
VNKLFGEKSASFREE	SERPINB2	126	P05120
IKFLTKGDNNEVDDR	SEC11C	121	Q9BY50
ASFIDDEAFKRLQGK	PRCC	386	Q92733
KRKFLESTDSFNNEL	SMARCE1	256	Q969G3
DSNLSFEEFKKLIRN	RLN1	121	P04808
SFGEVFKGIDNRTQK	STK24	46	Q9Y6E0
NKLVDNAFQRDTFKG	KERA	176	O60938
EAFFSKLQEFRETNK	MIIP	196	Q5JXC2
ELAKDFGDFKTQLTI	ARHGAP26	216	Q9UNA1
SDTNKRDLVGNDFKS	SETX	1186	Q7Z333
EAERKVKNSQSFFSG	NAPA	16	P54920
TSDDLEQFAKQFKQR	POU3F2	266	P20265
SAEQKRRFNIKLGFD	MLXIPL	656	Q9NP71
NKFATFLQRKNEESG	EXO1	481	Q9UQ84
KFDAFRKEVQSLGQA	SPTBN5	3146	Q9NRC6
GGDVENFERLFSKLK	AAGAB	256	Q6PD74
DFLKRQKTGRFATAE	BDH2	201	Q9BUT1
SSEKNLVFGTRIEKD	CCDC110	101	Q8TBZ0
RLFDDDETGKISFKN	CETN1	111	Q12798
LRTFNKLAEFGAEFK	CLN5	236	O75503
LKQIFGDKEDFRASQ	PNMA5	231	Q96PV4
SLEGKTNFFEKRVSE	RRM2B	316	Q7LG56
EKQFDQLLAFFDSRK	RNF17	191	Q9BXT8
ATNFGREKFIKLLDQ	UNC13C	1471	Q8NB66
SDKIGEADFNRSKEF	VWF	1506	P04275
DEDFQNLKLRSTGFT	MUC13	461	Q9H3R2
VLFTNARKFDGKDFR	MTREX	496	P42285
RGEKIKSDFFELLSN	TCERG1	791	O14776
KNTGKEEQRARDLFF	RRM1	316	P23921
ENISLEGKTNFFEKR	RRM2	351	P31350
TFKIQKTRLQREGFD	SLC27A1	596	Q6PCB7
TFLGKLNEAKQDFET	RPAP3	361	Q9H6T3
INSQLDKVEGRKFFV	THEM4	196	Q5T1C6
DFLATREKEKGNEAF	SPAG1	206	Q07617
FFEKNLKDVSFRLGS	XRCC4	96	Q13426
LKAEGFFRSNKVFVE	USP47	781	Q96K76
RDFLSGIQIEFKQSS	VPS13C	3181	Q709C8
DKNEDGRFTVFLNKS	TRAV29DV5	81	P04437
DTVLASFEDQRKKGF	ZBTB24	21	O43167
NKRGFIKAFTDNAVA	ERCC4	156	Q92889
TREKSFQRNESGKAF	ZNF701	276	Q9NV72
DGFEIFRLSKKITNN	TGS1	786	Q96RS0
DVSEKKEGRFTISFN	TRAV23DV6	81	A0A075B6W5
GEFRNEGNLEKFDKS	TLR4	261	O00206
SFEFKGKKESRRENQ	XRRA1	66	Q6P2D8
RKRFEQKSGAVFDEI	ZMYM4	11	Q5VZL5
TTEDLSFKKGERFQI	YES1	106	P07947
SFKKGERFQIINNTE	YES1	111	P07947
SDQFQLGRSKVFIKA	MYO1E	666	Q12965
TQKTFTLLGFKEDFQ	MYO5C	306	Q9NQX4