Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	immunoglobulin receptor binding	CR2 IGHA1 IGHA2 IGHM	2.97e-05	21	174	4	GO:0034987
GeneOntologyMolecularFunction	ATP hydrolysis activity	ERCC6 DYNC2H1 NAIP DNAH2 RNF213 RAD54L2 SMC5 NLRP3 MLH3 KIF14 KIF5A CDC6 SNRNP200 DDX28	3.37e-05	441	174	14	GO:0016887
GeneOntologyMolecularFunction	ATP-dependent activity	SETX ERCC6 DYNC2H1 NAIP DNAH2 RNF213 RAD54L2 SMC5 NLRP3 BPTF MLH3 KIF14 KIF5A CDC6 SNRNP200 DDX28	9.76e-05	614	174	16	GO:0140657
GeneOntologyMolecularFunction	microtubule binding	HAUS7 GOLGA8J CCDC88B GOLGA8M CCDC66 MTUS1 GOLGA8H KIF14 CDK5RAP2 KIF5A	3.83e-04	308	174	10	GO:0008017
GeneOntologyMolecularFunction	tubulin binding	HAUS7 GOLGA8J CCDC88B GOLGA8M CCDC66 MTUS1 GOLGA8H KIF14 CDK5RAP2 KIF5A GNAS HTT	3.87e-04	428	174	12	GO:0015631
GeneOntologyBiologicalProcess	complement activation, classical pathway	CR2 IGHA1 IGHA2 IGHM C2 MASP2	1.73e-06	44	173	6	GO:0006958
GeneOntologyBiologicalProcess	humoral immune response mediated by circulating immunoglobulin	CR2 IGHA1 IGHA2 IGHM C2 MASP2	1.33e-05	62	173	6	GO:0002455
GeneOntologyBiologicalProcess	complement activation	CR2 IGHA1 IGHA2 IGHM C2 MASP2	2.68e-05	70	173	6	GO:0006956
GeneOntologyCellularComponent	Golgi cis cisterna	GOLGA8J GOLGA8IP GOLGA8M GOLGA8H	1.57e-04	33	174	4	GO:0000137
GeneOntologyCellularComponent	dimeric IgA immunoglobulin complex	IGHA1 IGHA2	2.06e-04	3	174	2	GO:0071750
GeneOntologyCellularComponent	secretory dimeric IgA immunoglobulin complex	IGHA1 IGHA2	2.06e-04	3	174	2	GO:0071752
GeneOntologyCellularComponent	immunoglobulin complex, circulating	IGHA1 IGHA2 IGHM	3.54e-04	17	174	3	GO:0042571
GeneOntologyCellularComponent	canonical inflammasome complex	NAIP NLRP3 NLRP6	4.22e-04	18	174	3	GO:0061702
GeneOntologyCellularComponent	cis-Golgi network	GOLGA8J GOLGA8IP GOLGA8M GOLGA8H PCNT	7.23e-04	85	174	5	GO:0005801
Domain	-	MED16 WDR83 LYST SEMA4G ARHGEF10L MET FZR1 SCAP NBEAL2 STRN4 MAPKBP1 CORO7 HPS5 WDFY1	2.44e-06	333	171	14	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	MED16 WDR83 LYST SEMA4G ARHGEF10L MET FZR1 SCAP NBEAL2 STRN4 MAPKBP1 CORO7 HPS5 WDFY1	2.62e-06	335	171	14	IPR015943
Domain	WD40_repeat_dom	MED16 WDR83 LYST ARHGEF10L FZR1 SCAP NBEAL2 STRN4 MAPKBP1 CORO7 HPS5 WDFY1	1.94e-05	297	171	12	IPR017986
Domain	WD40	MED16 WDR83 LYST FZR1 SCAP NBEAL2 STRN4 MAPKBP1 CORO7 WDFY1	1.41e-04	259	171	10	PF00400
Domain	IG_LIKE	OBSCN LINGO3 SIGLEC15 OPCML SEMA4G IGSF22 HMCN2 IGHA1 IGHA2 NTM IGHM CD101 BTN2A3P ALPK2	1.76e-04	491	171	14	PS50835
Domain	WD40	MED16 WDR83 LYST FZR1 SCAP NBEAL2 STRN4 MAPKBP1 CORO7 WDFY1	1.86e-04	268	171	10	SM00320
Domain	WD40_repeat	MED16 WDR83 LYST FZR1 SCAP NBEAL2 STRN4 MAPKBP1 CORO7 WDFY1	2.10e-04	272	171	10	IPR001680
Domain	Ig-like_dom	OBSCN LINGO3 SIGLEC15 OPCML SEMA4G IGSF22 HMCN2 IGHA1 IGHA2 NTM IGHM CD101 BTN2A3P ALPK2	2.26e-04	503	171	14	IPR007110
Domain	WD_REPEATS_1	MED16 WDR83 LYST FZR1 SCAP NBEAL2 STRN4 MAPKBP1 CORO7 WDFY1	2.50e-04	278	171	10	PS00678
Domain	WD_REPEATS_2	MED16 WDR83 LYST FZR1 SCAP NBEAL2 STRN4 MAPKBP1 CORO7 WDFY1	2.57e-04	279	171	10	PS50082
Domain	WD_REPEATS_REGION	MED16 WDR83 LYST FZR1 SCAP NBEAL2 STRN4 MAPKBP1 CORO7 WDFY1	2.57e-04	279	171	10	PS50294
Domain	Ig_I-set	OBSCN LINGO3 OPCML IGSF22 HMCN2 NTM CD101 ALPK2	3.71e-04	190	171	8	IPR013098
Domain	I-set	OBSCN LINGO3 OPCML IGSF22 HMCN2 NTM CD101 ALPK2	3.71e-04	190	171	8	PF07679
Domain	GOLGA2L5	GOLGA8J GOLGA8M GOLGA8H	5.56e-04	18	171	3	PF15070
Domain	Golgin_A	GOLGA8J GOLGA8M GOLGA8H	5.56e-04	18	171	3	IPR024858
Domain	-	LRRC57 NAIP FBXL12 LINGO3 CPN2 NLRP3 NLRP6 LRCH4 SLITRK5 FBXL2	7.70e-04	321	171	10	3.80.10.10
Domain	Ig-like_fold	OBSCN LINGO3 SIGLEC15 OPCML SEMA4G MET IGSF22 HMCN2 IGHA1 IGHA2 NTM IGHM CD101 BTN2A3P RIMBP2 ALPK2	7.88e-04	706	171	16	IPR013783
Domain	P-loop_NTPase	EFL1 SETX ERCC6 DYNC2H1 NAIP DNAH2 RNF213 RAD54L2 SMC5 NLRP3 NLRP6 TRANK1 KIF14 KIF5A GNAS CDC6 SNRNP200 DDX28	7.93e-04	848	171	18	IPR027417
Domain	WD40_repeat_CS	WDR83 LYST FZR1 SCAP STRN4 CORO7 WDFY1	7.96e-04	164	171	7	IPR019775
Domain	L_dom-like	LRRC57 NAIP FBXL12 LINGO3 CPN2 NLRP3 NLRP6 LRCH4 SLITRK5 FBXL2	9.07e-04	328	171	10	IPR032675
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SPHK2 FRAS1 KMT2B SZT2 HECTD4 OBSCN FBXL12 NPHP4 LYST MBD3 ARHGEF10L FZR1 THADA SCAP CELSR3 DOK4 NBEAL2 STRN4 DIAPH2 LRP5 PCNX1 MAPKBP1 RGL2 ABTB2 HTT PCNT	9.98e-11	1105	178	26	35748872
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TET2 SETX SZT2 HECTD4 TOPBP1 XPO4 ARHGEF10L TRANK1 CELSR3 MTUS1 NBEAL2 CDK5RAP2 PCNX1 ARHGAP20 HPS5	1.09e-07	529	178	15	14621295
Pubmed	CDK5RAP2 expression during murine and human brain development correlates with pathology in primary autosomal recessive microcephaly.	GOLGA8J GFAP GOLGA8M GOLGA8H CDK5RAP2	2.00e-07	26	178	5	22806269
Pubmed	Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice.	GOLGA8J GFAP GOLGA8M GOLGA8H PCNT	5.06e-07	31	178	5	17765678
Pubmed	Characterization, quantification, and assessment of immune protection potential of secretory immunoglobulin A in colostrum samples from Saudi women.	IGHA1 IGHA2 IGHM	5.25e-07	4	178	3	24145934
Pubmed	Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.	DYNC2H1 OBSCN RNF213	5.25e-07	4	178	3	26147384
Pubmed	Human plasma-derived polymeric IgA and IgM antibodies associate with secretory component to yield biologically active secretory-like antibodies.	IGHA1 IGHA2 IGHM	1.31e-06	5	178	3	23250751
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TRERF1 DLGAP2 GOLGA8J ZNRD2 HECTD4 SIPA1 LMTK3 MBD3 GOLGA8M GOLGA8H STRN4 GLUL DIAPH2 CDK5RAP2 RIMBP2 KIF5A CTNND2 PCNT	2.54e-06	963	178	18	28671696
Pubmed	Dynamics of the rhomboid-like protein RHBDD2 expression in mouse retina and involvement of its human ortholog in retinitis pigmentosa.	GOLGA8J GOLGA8M GOLGA8H GLUL	3.71e-06	21	178	4	23386608
Pubmed	Mechanism of primitive duct formation in the pancreas and submandibular glands: a role for SDF-1.	GOLGA8J GOLGA8M GOLGA8H PCNT	3.71e-06	21	178	4	20003423
Pubmed	Comparative analysis of vertebrates reveals that mouse primordial oocytes do not contain a Balbiani body.	GOLGA8J GOLGA8M GOLGA8H PCNT	4.51e-06	22	178	4	34897463
Pubmed	A Golgi Lipid Signaling Pathway Controls Apical Golgi Distribution and Cell Polarity during Neurogenesis.	GOLGA8J GOLGA8M GOLGA8H PCNT	7.71e-06	25	178	4	29587143
Pubmed	Characterization of the piRNA complex from rat testes.	GOLGA8J KMT2B RAD54L2 GOLGA8M ZDHHC23 GOLGA8H ARHGAP20	8.28e-06	140	178	7	16778019
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PCDHGB1 KIAA0232 WASF3 HECTD4 NAIP OBSCN RNF213 GRIK1 GMPS ANKRD44 BPTF THADA ZNF544 AIG1 KIAA1328 LRP5 GNAS HPS5 SLC4A5 MTARC1 HTT PCNT	8.39e-06	1489	178	22	28611215
Pubmed	Mouse oocytes develop in cysts with the help of nurse cells.	GOLGA8J GOLGA8M GOLGA8H PCNT	9.08e-06	26	178	4	35623357
Pubmed	PTEN dephosphorylates Abi1 to promote epithelial morphogenesis.	GOLGA8J GOLGA8M GOLGA8H PCNT	9.08e-06	26	178	4	32673396
Pubmed	Dynein activating adaptor BICD2 controls radial migration of upper-layer cortical neurons in vivo.	GOLGA8J GOLGA8M GOLGA8H PCNT	9.08e-06	26	178	4	31655624
Pubmed	Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis.	GOLGA8J GFAP GOLGA8M GOLGA8H	9.08e-06	26	178	4	31138815
Pubmed	Dual function of Yap in the regulation of lens progenitor cells and cellular polarity.	GOLGA8J GOLGA8M GOLGA8H PCNT	9.08e-06	26	178	4	24384391
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TET2 OBSCN RNF213 SEMA4G ARHGEF10L CDK5RAP2	1.40e-05	101	178	6	10997877
Pubmed	Shaping of Intestinal Microbiota in Nlrp6- and Rag2-Deficient Mice Depends on Community Structure.	NLRP3 NLRP6 IGHM	1.54e-05	10	178	3	29281837
Pubmed	Immune effectors required for hepatitis B virus clearance.	LYST PRF1 IGHM	1.54e-05	10	178	3	20080755
Pubmed	Bacterial inhibition of Fas-mediated killing promotes neuroinvasion and persistence.	MET PRF1 IGHM	2.11e-05	11	178	3	35296858
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	KIAA0232 WASF3 SMC5 SCAP PCNX1 HPS5 SNRNP200 PCNT	2.25e-05	225	178	8	12168954
Pubmed	Gene-targeted deletion of OPCML and Neurotrimin in mice does not yield congenital heart defects.	OPCML NTM	2.60e-05	2	178	2	24616287
Pubmed	TERT promoter mutations and GABP transcription factors in carcinogenesis: More foes than friends.	TERT GABPA	2.60e-05	2	178	2	32768523
Pubmed	TERT Promoter Mutations Enhance Telomerase Activation by Long-Range Chromatin Interactions.	TERT GABPA	2.60e-05	2	178	2	27807101
Pubmed	Identification of mammalian orthologs associates PYPAF5 with distinct functional roles.	NLRP3 NLRP6	2.60e-05	2	178	2	12633874
Pubmed	Candida albicans SC5314 inhibits NLRP3/NLRP6 inflammasome expression and dampens human intestinal barrier activity in Caco-2 cell monolayer model.	NLRP3 NLRP6	2.60e-05	2	178	2	31629100
Pubmed	NLRP3 and NLRP6 expression in pterygium and normal conjunctiva and their relationship with pterygium formation and recurrence.	NLRP3 NLRP6	2.60e-05	2	178	2	35068231
Pubmed	Ezh2 regulates the Lin28/let-7 pathway to restrict activation of fetal gene signature in adult hematopoietic stem cells.	TET2 EZH2	2.60e-05	2	178	2	26773568
Pubmed	Fructose-1,6-bisphosphatase 1 dephosphorylates and inhibits TERT for tumor suppression.	TERT FBP1	2.60e-05	2	178	2	38538923
Pubmed	Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome.	LYST PRF1	2.60e-05	2	178	2	21878672
Pubmed	Increased in vitro glial fibrillary acidic protein expression, telomerase activity, and telomere length after productive human immunodeficiency virus-1 infection in murine astrocytes.	TERT GFAP	2.60e-05	2	178	2	24254728
Pubmed	Molecular profiling of chronic myelomonocytic leukemia reveals diverse mutations in >80% of patients with TET2 and EZH2 being of high prognostic relevance.	TET2 EZH2	2.60e-05	2	178	2	21339759
Pubmed	Aggregatibacter actinomycetemcomitans targets NLRP3 and NLRP6 inflammasome expression in human mononuclear leukocytes.	NLRP3 NLRP6	2.60e-05	2	178	2	22503597
Pubmed	The structure and function of human IgA.	IGHA1 IGHA2	2.60e-05	2	178	2	2241915
Pubmed	Histone deacetylases, Mbd3/NuRD, and Tet2 hydroxylase are crucial regulators of epithelial-mesenchymal plasticity and tumor metastasis.	TET2 MBD3	2.60e-05	2	178	2	31666683
Pubmed	Importance of the CEP215-pericentrin interaction for centrosome maturation during mitosis.	CDK5RAP2 PCNT	2.60e-05	2	178	2	24466316
Pubmed	Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation.	SPHK2 TERT	2.60e-05	2	178	2	26082434
Pubmed	Desiccating stress worsens alkali burn injury by magnifying caspase-8-induced imbalance of NLRP3 and NLRP6.	NLRP3 NLRP6	2.60e-05	2	178	2	28479336
Pubmed	SNaPshot Assay in Quantitative Detection of Allelic Nondisjunction in Down Syndrome.	GART GRIK1	2.60e-05	2	178	2	22931243
Pubmed	Centriole-independent mitotic spindle assembly relies on the PCNT-CDK5RAP2 pericentriolar matrix.	CDK5RAP2 PCNT	2.60e-05	2	178	2	33170211
Pubmed	OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer.	OPCML NTM	2.60e-05	2	178	2	12819783
Pubmed	alpha Pix enhances mutant huntingtin aggregation.	ARHGEF6 HTT	2.60e-05	2	178	2	19969308
Pubmed	Long-Range Chromatin Interactions Drive Mutant TERT Promoter Activation.	TERT GABPA	2.60e-05	2	178	2	27650951
Pubmed	Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer.	TERT GABPA	2.60e-05	2	178	2	25977370
Pubmed	Loss of histone lysine methyltransferase EZH2 confers resistance to tyrosine kinase inhibitors in non-small cell lung cancer.	EZH2 MET	2.60e-05	2	178	2	32920200
Pubmed	Cloning of neurotrimin defines a new subfamily of differentially expressed neural cell adhesion molecules.	OPCML NTM	2.60e-05	2	178	2	7891157
Pubmed	ADAR3 alleviated inflammation and pyroptosis of neuropathic pain by targeting NLRP3 in chronic constriction injury mice.	ADARB2 NLRP3	2.60e-05	2	178	2	34419568
Pubmed	Integrator complex subunit 15 controls mRNA splicing and is critical for eye development.	GFAP INTS15	2.60e-05	2	178	2	36851842
Pubmed	BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits.	TERT BPTF	2.60e-05	2	178	2	30419422
Pubmed	Suppressor of Ty homolog-5, a novel tumor-specific human telomerase reverse transcriptase promoter-binding protein and activator in colon cancer cells.	TERT SUPT5H	2.60e-05	2	178	2	26418880
Pubmed	Globozoospermia and lack of acrosome formation in GM130-deficient mice.	GOLGA8J GOLGA8M GOLGA8H	3.63e-05	13	178	3	28055014
Pubmed	GM130 regulates pulmonary surfactant protein secretion in alveolar type II cells.	GOLGA8J GOLGA8M GOLGA8H	3.63e-05	13	178	3	33740186
Pubmed	Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice.	GOLGA8J GOLGA8M GOLGA8H	3.63e-05	13	178	3	28028212
Pubmed	GOLGA2 loss causes fibrosis with autophagy in the mouse lung and liver.	GOLGA8J GOLGA8M GOLGA8H	3.63e-05	13	178	3	29128360
Pubmed	Loss of GM130 does not impair oocyte meiosis and embryo development in mice.	GOLGA8J GOLGA8M GOLGA8H	3.63e-05	13	178	3	32873390
Pubmed	GM130, a cis-Golgi protein, regulates meiotic spindle assembly and asymmetric division in mouse oocyte.	GOLGA8J GOLGA8M GOLGA8H	3.63e-05	13	178	3	21552007
Pubmed	A human MAP kinase interactome.	SETX KIAA0232 CCDC88B GFAP KIAA1328 GLUL DIAPH2 KIF5A CPLANE1 RGL2 SNRNP200	4.55e-05	486	178	11	20936779
Pubmed	Golgb1 regulates protein glycosylation and is crucial for mammalian palate development.	GOLGA8J GOLGA8M GOLGA8H	4.60e-05	14	178	3	27226319
Pubmed	Cdk1 protects against oxygen-glucose deprivation and reperfusion-induced Golgi fragmentation and apoptosis through mediating GM130 phosphorylation.	GOLGA8J GOLGA8M GOLGA8H	4.60e-05	14	178	3	37831422
Pubmed	GM130 and p115 play a key role in the organisation of the early secretory pathway during skeletal muscle differentiation.	GOLGA8J GOLGA8M GOLGA8H	4.60e-05	14	178	3	30630895
Pubmed	Oligoasthenoteratospermia and sperm tail bending in PPP4C-deficient mice.	GOLGA8J GOLGA8M GOLGA8H	4.60e-05	14	178	3	33543287
Pubmed	Golgi disruption and early embryonic lethality in mice lacking USO1.	GOLGA8J GOLGA8M GOLGA8H	5.73e-05	15	178	3	23185636
Pubmed	Structure and function of immunoglobulins.	IGHA1 IGHA2 IGHM	5.73e-05	15	178	3	20176268
Pubmed	Mouse oocytes within germ cell cysts and primordial follicles contain a Balbiani body.	GOLGA8J GOLGA8M GOLGA8H	5.73e-05	15	178	3	17189423
Pubmed	GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules.	GOLGA8J GOLGA8M GOLGA8H	5.73e-05	15	178	3	26165940
Pubmed	The a3 isoform of V-ATPase regulates insulin secretion from pancreatic beta-cells.	GOLGA8J GOLGA8M GOLGA8H	5.73e-05	15	178	3	17046993
Pubmed	WDR38, a novel equatorial segment protein, interacts with the GTPase protein RAB19 and Golgi protein GM130 to play roles in acrosome biogenesis.	GOLGA8J GOLGA8M GOLGA8H	5.73e-05	15	178	3	37635409
Pubmed	Golga5 is dispensable for mouse embryonic development and postnatal survival.	GOLGA8J GOLGA8M GOLGA8H	5.73e-05	15	178	3	28509431
Pubmed	Calumin, a novel Ca2+-binding transmembrane protein on the endoplasmic reticulum.	GOLGA8J GOLGA8M GOLGA8H	5.73e-05	15	178	3	17204322
Pubmed	Demonstration of the expression and the enzymatic activity of N-acetylglucosaminyltransferase IX in the mouse brain.	GOLGA8J GOLGA8M GOLGA8H	5.73e-05	15	178	3	16413118
Pubmed	RhoA-mediated FMNL1 regulates GM130 for actin assembly and phosphorylates MAPK for spindle formation in mouse oocyte meiosis.	GOLGA8J GOLGA8M GOLGA8H	5.73e-05	15	178	3	26083584
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	SETX NPHP4 BPTF MTMR6 TMEM267 SUPT5H GLUL PCNX1 CDC25C ZNF114	6.67e-05	420	178	10	28065597
Pubmed	LIM kinase 2 is widely expressed in all tissues.	GOLGA8J GOLGA8M GOLGA8H	7.03e-05	16	178	3	16399995
Pubmed	Molecular motor KIF1C is not essential for mouse survival and motor-dependent retrograde Golgi apparatus-to-endoplasmic reticulum transport.	GOLGA8J GOLGA8M GOLGA8H	7.03e-05	16	178	3	11784862
Pubmed	Molecular characterization of mitocalcin, a novel mitochondrial Ca2+-binding protein with EF-hand and coiled-coil domains.	GOLGA8J GOLGA8M GOLGA8H	7.03e-05	16	178	3	16336229
Pubmed	SLC24A5 encodes a trans-Golgi network protein with potassium-dependent sodium-calcium exchange activity that regulates human epidermal melanogenesis.	GOLGA8J GOLGA8M GOLGA8H	7.03e-05	16	178	3	18166528
Pubmed	p125/Sec23-interacting protein (Sec23ip) is required for spermiogenesis.	GOLGA8J GOLGA8M GOLGA8H	7.03e-05	16	178	3	21640725
Pubmed	BCAS2 regulates oocyte meiotic prophase I by participating in mRNA alternative splicing.	GOLGA8J GOLGA8M GOLGA8H DIAPH2	7.67e-05	44	178	4	38085152
Pubmed	An interaction proteomics survey of transcription factor binding at recurrent TERT promoter mutations.	TERT GABPA	7.79e-05	3	178	2	26553150
Pubmed	TET2, ASXL1 and EZH2 mutations in Chinese with myelodysplastic syndromes.	TET2 EZH2	7.79e-05	3	178	2	23099237
Pubmed	Triple deletion of TP53, PCNT, and CEP215 promotes centriole amplification in the M phase.	CDK5RAP2 PCNT	7.79e-05	3	178	2	34233584
Pubmed	Clinical presentation and outcome of pediatric patients with hemophagocytic lymphohistiocytosis in China: A retrospective multicenter study.	LYST PRF1	7.79e-05	3	178	2	27781387
Pubmed	BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis in Tet2 Clonal Hematopoiesis.	TET2 NLRP3	7.79e-05	3	178	2	37781816
Pubmed	Identification of histological markers for malignant glioma by genome-wide expression analysis: dynein, alpha-PIX and sorcin.	DYNC2H1 ARHGEF6	7.79e-05	3	178	2	16320026
Pubmed	NRP2 transcriptionally regulates its downstream effector WDFY1.	BPTF WDFY1	7.79e-05	3	178	2	27026195
Pubmed	LncRNA TUG1 Demethylated by TET2 Promotes NLRP3 Expression, Contributes to Cerebral Ischemia/Reperfusion Inflammatory Injury.	TET2 NLRP3	7.79e-05	3	178	2	33853366
Pubmed	Astrocyte S100β expression and selective differentiation to GFAP and GS in the entorhinal cortex during ageing in the 3xTg-Alzheimer's disease mouse model.	GFAP GLUL	7.79e-05	3	178	2	38159478
Pubmed	Expression of Fraser syndrome genes in normal and polycystic murine kidneys.	FRAS1 FREM3	7.79e-05	3	178	2	21993971
Pubmed	Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders.	TET2 EZH2	7.79e-05	3	178	2	24218139
Pubmed	TET2-mutant clonal hematopoiesis and risk of gout.	TET2 NLRP3	7.79e-05	3	178	2	35714308
Pubmed	The role of LINC01419 in regulating the cell stemness in lung adenocarcinoma through recruiting EZH2 and regulating FBP1 expression.	EZH2 FBP1	7.79e-05	3	178	2	36050791
Pubmed	The superficial glia limitans of mouse and monkey brain and spinal cord.	GFAP GLUL	7.79e-05	3	178	2	23674345
Pubmed	Aberrant expression of NLRP3, NLRC4 and NLRP6 inflammasomes in patients with primary immune thrombocytopenia.	NLRP3 NLRP6	7.79e-05	3	178	2	30802690
Pubmed	Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency.	TET2 KMT2B	7.79e-05	3	178	2	31844322
Pubmed	Long noncoding RNA OIP5-AS1 aggravates cell proliferation, migration in gastric cancer by epigenetically silencing NLRP6 expression via binding EZH2.	EZH2 NLRP6	7.79e-05	3	178	2	31219209
Pubmed	Oocytes mount a noncanonical DNA damage response involving APC-Cdh1-mediated proteolysis.	SETX FZR1	7.79e-05	3	178	2	32328643
Pubmed	Trigger-dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis.	LYST PRF1	7.79e-05	3	178	2	32419134
Interaction	HELZ2 interactions	ZNRD2 SIRT7 EZH2 MTMR6 MEX3A FBP1 KIF14	1.59e-06	67	171	7	int:HELZ2
Interaction	TOP3B interactions	SPHK2 FRAS1 KMT2B SZT2 HECTD4 OBSCN PLEKHA4 FBXL12 NPHP4 LYST MBD3 ARHGEF10L FZR1 THADA SCAP CELSR3 DOK4 NBEAL2 STRN4 DIAPH2 KIF14 LRP5 PCNX1 GNAS MAPKBP1 RGL2 ABTB2 DDX28 HTT PCNT	6.06e-06	1470	171	30	int:TOP3B
Interaction	BAZ1B interactions	ERCC6 PLEKHA4 SIRT7 LMTK3 SMC5 MBD3 FZR1 MEX3A SUPT5H KIF14	9.93e-06	204	171	10	int:BAZ1B
Interaction	CRNKL1 interactions	ERCC6 PLEKHA4 WDR83 SIRT7 SMC5 EZH2 FZR1 SUPT5H SNRNP200	2.09e-05	177	171	9	int:CRNKL1
Interaction	NPTN interactions	SETX DYNC2H1 FBXL12 XPO4 RNF213 TSPYL1 ANKRD44 THADA NBEAL2 KIF14 HTT	2.65e-05	278	171	11	int:NPTN
Interaction	DYNLL1 interactions	DYNC2H1 PLEKHA4 SMC5 EZH2 TERT RSBN1 FZR1 STRN4 GLUL KIF14 CDK5RAP2 KIF5A WWC1 HTT PCNT	3.11e-05	510	171	15	int:DYNLL1
Interaction	DUSP16 interactions	HAUS7 SZT2 DYNC2H1 KIAA0232 GLE1 CDK5RAP2 HPS5 SNRNP200 HTT PCNT	3.61e-05	237	171	10	int:DUSP16
GeneFamily	WD repeat domain containing	MED16 WDR83 LYST FZR1 SCAP NBEAL2 STRN4 MAPKBP1 CORO7 WDFY1	7.87e-06	262	117	10	362
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	OBSCN LINGO3 OPCML IGSF22 HMCN2 NTM CD101 ALPK2	9.96e-06	161	117	8	593
GeneFamily	I-set domain containing\|IgLON cell adhesion molecules	OPCML NTM	4.10e-04	5	117	2	1052
GeneFamily	NLR family	NAIP NLRP3 NLRP6	5.47e-04	25	117	3	666
GeneFamily	WD repeat domain containing\|BEACH domain containing	LYST NBEAL2	1.45e-03	9	117	2	1230
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	ADAM19 RNF213 ZNF407 LYST ANKRD44 PNPT1 MLH3 ZDHHC23 NUS1 HTT	2.64e-09	176	179	10	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	ADAM19 RNF213 ZNF407 LYST PNPT1 MLH3 ZDHHC23 NUS1 HTT	4.40e-08	177	179	9	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	Transverse-T_cell-CD8_T\|T_cell / Region, Cell class and subclass	LYST IGLV3-19 PDLIM1 IGHA1 IGHA2 PRF1 IGHM GLUL	1.43e-06	198	179	8	3b0613171cc7d5320f0b525cc6836f21874b0505
ToppCell	Caecum-T_cell-CD8_T\|T_cell / Region, Cell class and subclass	LYST IGLV3-19 PDLIM1 IGHA1 IGHA2 PRF1 IGHM GLUL	1.54e-06	200	179	8	40e435f5dd1a0f6554f87dc1e170a740fd733d5b
ToppCell	TCGA-Blood_and_Bone_Marrow-Primary_Blood_Derived_Cancer_-_Peripheral_Blood-Leukemia-Acute_Myeloid_Leukemia-8\|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9	MCMBP NAIP FAM200B NLRP3 SLCO4C1 CD101 WDFY1	2.45e-06	149	179	7	0c18acfc5f0a9dd25ee5c38f97498b3278e65b42
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WASF3 PLEKHA4 HEATR5A ADAMTS13 CCDC88B LYST PIGQ	3.46e-06	157	179	7	8c42af7aa1f1b6f4fe2f8d00a8b4a800f121e804
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WASF3 PLEKHA4 HEATR5A ADAMTS13 CCDC88B LYST PIGQ	3.46e-06	157	179	7	ee1be3c756b72fceac6b4ccb416dd4bd031a2193
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WASF3 PLEKHA4 HEATR5A ADAMTS13 CCDC88B LYST PIGQ	3.46e-06	157	179	7	008f938a338f43c3251dcac574f1b4f689926c71
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGLV3-19 MET IGHA1 IGHA2 KIF14 CDC6 CDC25C	6.07e-06	171	179	7	13126a3fbee181412c13ffb0c347277b9d8f16f7
ToppCell	Adult-Immune-B_cell-D175\|Adult / Lineage, Cell type, age group and donor	ADAM19 CR2 IGHA1 IGHA2 IGHM KIF5A CDC6	6.07e-06	171	179	7	355a246f3395900342d400f6f7c6640cba0d4d5d
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	TRERF1 ADAM19 LINS1 BRF1 CORO7 PHF10 SNRNP200	6.80e-06	174	179	7	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	severe_influenza-Plasmablast\|World / disease group, cell group and cell class (v2)	DLGAP2 CCDC168 TERT MET IGHA1 IGHA2 KIF14	7.06e-06	175	179	7	e6d6c44510d5dc4eb0bae820125e42366f7a4e74
ToppCell	Healthy_donor-Plasmablast\|Healthy_donor / disease group, cell group and cell class (v2)	TERT IGLV3-19 MET IGHA1 IGHA2 KIF14 CDC25C	7.89e-06	178	179	7	388b8b4fa20dcc6e9ae4b06118e20b2c20c52bde
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 CCDC88B ANKRD44 TRANK1 IGHA1 IGHA2 IGHM	8.80e-06	181	179	7	5a4fe0eca7cbc9cbc8a2fdbe795a7c5f4052a659
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAM19 EZH2 TERT IGHA1 IGHA2 IGHM KIF14	1.13e-05	188	179	7	567b08514d9d84cbb40f9b7a679eec304f023428
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	ADAM19 XPO4 RNF213 LYST ANKRD44 PNPT1 ZDHHC23	1.25e-05	191	179	7	9454f642c3621370fa23640b631301346b300950
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADAM19 ZDHHC23 PDLIM1 IGHA1 IGHA2 IGHM ARHGAP20	1.34e-05	193	179	7	749faa5c592ee354733f5a7363a4277ef3462b93
ToppCell	E15.5-Epithelial-epithelial_progenitor_cell-epi_progenitor\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EZH2 GMPS SLCO4C1 PDLIM1 NTM CTNND2 CDC6	1.34e-05	193	179	7	d88b6c9d1b1f88a80afc18e26406d8b7a8d95e81
ToppCell	PBMC-Mild-Lymphocyte-B\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADAM19 CR2 ZDHHC23 PDLIM1 IGHA1 IGHA2 IGHM	1.38e-05	194	179	7	b6328575eedb19e0ad7f4d03041672f3dc146da0
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ADAM19 CR2 LYST ANKRD13A ANKRD44 BPTF IGHM	1.38e-05	194	179	7	ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ARHGEF10L MET AIG1 FHIP1A ABTB2 WWC1	1.38e-05	194	179	7	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	PBMC-Mild-Lymphocyte-B\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ADAM19 CR2 ZDHHC23 PDLIM1 IGHA1 IGHA2 IGHM	1.38e-05	194	179	7	b16b96e42ea9734731342d4c41ff1711bd149462
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasmablast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CCDC88B FZR1 IGHA1 IGHA2 KIF14 CDC6 CDC25C	1.43e-05	195	179	7	a045fb8a377e54fb57fef1181d4c3fc15d627ef6
ToppCell	COVID-19_Mild-PLT_5\|COVID-19_Mild / Disease Group and Platelet Clusters	TRERF1 TOPBP1 RNF213 IGLV3-19 PNPT1 SCAP PRF1	1.43e-05	195	179	7	bdf9a6ea1bd83c72a834c45f86ce3f4643a9bef3
ToppCell	Lung_Parenchyma-Control-Lymphocyte-B-Plasmablast-Plasmablast-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CR2 TERT IGHA1 IGHA2 IGHM CDC6 CDC25C	1.52e-05	197	179	7	0d38d126b1e653398426255e95449f1150eac1b0
ToppCell	Parenchyma_Control_(B.)-Immune-TX-Plasma_cells\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	CR2 TERT IGHA1 IGHA2 IGHM CDC6 CDC25C	1.52e-05	197	179	7	7ffb373d5b72c67e4816f14ea9a7a2024dc7a93a
ToppCell	Lung_Parenchyma-Control-Lymphocyte-B-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CR2 TERT IGHA1 IGHA2 IGHM CDC6 CDC25C	1.52e-05	197	179	7	2e76e9ebd8702bfeefd396cbf5114eee0f24c19b
ToppCell	Lung_Parenchyma-Control-Lymphocyte-B-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CR2 TERT IGHA1 IGHA2 IGHM CDC6 CDC25C	1.52e-05	197	179	7	207fce47e547fafbaf64a22efe3488e74bf19bed
ToppCell	wk_20-22-Hematologic_Lymphocytic-B-Large_pre-B\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	EZH2 TERT PDLIM1 IGHM KIF14 CDC6 CDC25C	1.52e-05	197	179	7	cebf47d66f425c84d3fea962e11f5bf4bfe2e60f
ToppCell	Sepsis-ICU-SEP-Lymphocyte-B-Plasmablast\|ICU-SEP / Disease, condition lineage and cell class	TERT MET PDLIM1 IGHA1 IGHA2 MCUR1 CDC6	1.63e-05	199	179	7	09f02aaedf19f895a7b6f8eb939fd346b1df75f1
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DLGAP2 ADAM19 LINGO3 LYST NLRP3 ANKRD44 ALPK2	1.63e-05	199	179	7	7b3d4c62b11268c7c1599600d8a7b331287cf21a
ToppCell	COVID_vent\|World / Disease condition, Lineage, Cell class and subclass	ADAM19 GART IGHA1 IGHA2 IGHM CDC6 MTARC1	1.68e-05	200	179	7	1d88e5cc4534073f27a7562e1c4b884bd67f09d9
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-B\|COVID-19_Mild / Disease, condition lineage and cell class	ADAM19 CR2 ZDHHC23 PDLIM1 IGHA1 IGHA2 IGHM	1.68e-05	200	179	7	11b51dfca161342d92126e0a83d10864348ba3ef
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_A\|368C / Donor, Lineage, Cell class and subclass (all cells)	ZNF805 NUDT13 GOLGA8M SLCO4C1 PRF1 TMEM44	2.79e-05	146	179	6	0e38e1fa40b1fcd1bb61f7af7cc2206846c192ae
ToppCell	Healthy_Control-Lymphoid-B-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	ADAM19 CR2 HMCN2 IGHA1 IGHA2 IGHM	5.16e-05	163	179	6	d84bd41b4494c7d5c7f88d511bfe481fb12f079d
ToppCell	Healthy_Control-Lymphoid-B\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	ADAM19 CR2 HMCN2 IGHA1 IGHA2 IGHM	5.16e-05	163	179	6	0f723ec2503afa1b3ebb0754972438ffb6e6179d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 PRF1 NTM KIF5A CTNND2 ARHGEF6	5.71e-05	166	179	6	f742d15b02a6f651bbd00f53e3d871f40d05a03d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 PRF1 NTM KIF5A CTNND2 ARHGEF6	5.71e-05	166	179	6	0f013bb5fdb72e88c2fc73d60cd01551a2db6341
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 PRF1 NTM KIF5A CTNND2 ARHGEF6	5.71e-05	166	179	6	e941df9a1091164edde3def8fc7d410186b2bd88
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 PRF1 NTM KIF5A CTNND2 ARHGEF6	5.71e-05	166	179	6	aeda46bea5d8463c24a83b98b9ed92d962d733e5
ToppCell	IIH-naiveBc\|IIH / Condition, Cell_class and T cell subcluster	IGLV3-19 ZDHHC23 PDLIM1 IGHA1 IGHA2 IGHM	6.11e-05	168	179	6	8450ed6720d308c711dfbc76652e5821be7b8e93
ToppCell	IIH-naiveBc-\|IIH / Condition, Cell_class and T cell subcluster	IGLV3-19 ZDHHC23 PDLIM1 IGHA1 IGHA2 IGHM	6.11e-05	168	179	6	27b500f79aedc4669988670c92ff1a47dcbdf2a0
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAM19 CR2 IGHA1 IGHA2 IGHM RIMBP2	6.95e-05	172	179	6	172e3c78f8e97988a4fd8624514e731282ddc16d
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAM19 CR2 IGHA1 IGHA2 IGHM RIMBP2	6.95e-05	172	179	6	5fb0ea6145892a258696197b3feed9760187e712
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAM19 CR2 IGHA1 IGHA2 IGHM RIMBP2	6.95e-05	172	179	6	2214cc37d7c21b868768d3f74ca4631d339d37b3
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAM19 CR2 IGHA1 IGHA2 IGHM RIMBP2	6.95e-05	172	179	6	07620728a6cdeea805e1365e588be096c17a370c
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Necab1_(MGE-derived_cortical_interneurons--basket_cells)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	VAX1 CR2 TERT ALPK2	7.05e-05	55	179	4	ed871246b0ada07e8fe87a68584c06986977d0bd
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Necab1_(MGE-derived_cortical_interneurons--basket_cells)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	VAX1 CR2 TERT ALPK2	7.05e-05	55	179	4	51a76e6cb45976ce99a41fb6cd5b94c632ec7c5b
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Lymphocytic-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEKHA4 RAD54L2 GFAP MLH3 MEX3A DDX28	7.41e-05	174	179	6	6987fe7959afce347282f632abc16d800ccab7c4
ToppCell	Healthy/Control-Plasmablast\|Healthy/Control / Disease group and Cell class	IGLV3-19 MET IGHA1 IGHA2 KIF14 CDC25C	7.41e-05	174	179	6	97d19ef3240a1f648c6befaabb9ce45ad469cbce
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRERF1 ADAM19 HECTD4 FBP1 NTM HPS5	7.65e-05	175	179	6	1d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRERF1 ADAM19 HECTD4 FBP1 NTM HPS5	7.65e-05	175	179	6	427a7ee92fe16a90625946492062d37aa0f7235b
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHDC9 THADA KIF5A CTNND2 PHF10 ARHGEF6	7.90e-05	176	179	6	6b4afd2c9268172063fe5832896bea15e862579e
ToppCell	Control-B_cells\|Control / group, cell type (main and fine annotations)	ADAM19 CR2 ANKRD44 IGHA1 IGHA2 IGHM	7.90e-05	176	179	6	9125caa27bf790f6b1b960a86c09b4bcb1b58641
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RNF213 GOLGA8IP TRANK1 PRF1 PCNX1 CPLANE1	8.15e-05	177	179	6	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	COVID-19-lung-B_cells\|lung / Disease (COVID-19 only), tissue and cell type	ADAM19 CR2 ANKRD44 IGHA1 IGHA2 IGHM	8.15e-05	177	179	6	f54691e5558091c1734ab15153a10bff15ed171e
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RNF213 GOLGA8IP TRANK1 PRF1 PCNX1 CPLANE1	8.15e-05	177	179	6	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADAM19 LINGO3 PDLIM1 IGHA1 IGHA2 IGHM	8.15e-05	177	179	6	37d1abe1a9d8f2b8f4d146bbf1db94104eab6593
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	RNF213 GOLGA8IP TRANK1 PRF1 PCNX1 CPLANE1	8.15e-05	177	179	6	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	RNF213 GOLGA8IP TRANK1 PRF1 PCNX1 CPLANE1	8.15e-05	177	179	6	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RNF213 GOLGA8IP TRANK1 PRF1 PCNX1 CPLANE1	8.15e-05	177	179	6	d5aeda113afaa2425874394610344570c9078478
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 HEATR5A NBEAL2 FBXL2 FHIP1A WWC1	8.15e-05	177	179	6	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	Children_(3_yrs)-Immune-B_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAM19 CR2 ANKRD44 IGHA1 IGHA2 IGHM	8.67e-05	179	179	6	31411780f1a44bf2d102f288416e97eacec4b6b6
ToppCell	IPF-Lymphoid-B\|World / Disease state, Lineage and Cell class	ADAM19 CR2 ANKRD44 IGHA1 IGHA2 IGHM	8.94e-05	180	179	6	30f9398c9b784f49470847a025bac90687e997a1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ADARB2 ARHGEF10L MET NTM WWC1	9.21e-05	181	179	6	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	Healthy-B_memory\|Healthy / disease group, cell group and cell class	CR2 ZDHHC23 PDLIM1 IGHA1 IGHA2 IGHM	9.21e-05	181	179	6	7b903076efb90026b9845af0c7a840901451193a
ToppCell	normal_Lung-B_lymphocytes-Plasma_cells\|normal_Lung / Location, Cell class and cell subclass	LMTK3 IGLV3-19 IGHA1 IGHA2 IGHM	9.35e-05	113	179	5	7ec8c1712977d3b8e861d2743ff7bd1797ab35df
ToppCell	cellseq-Immune-Lymphocytic_B-Lymphocytic_B-B\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAM19 CR2 ANKRD44 IGHA1 IGHA2 IGHM	9.49e-05	182	179	6	dc6b5ce410c1a7cade60ae17cbbe8548c088cba8
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 DLGAP2 FRAS1 LINGO3 TRANK1 ARHGAP20	9.49e-05	182	179	6	d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ADARB2 ARHGEF10L MET NTM WWC1	9.49e-05	182	179	6	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 DLGAP2 FRAS1 LINGO3 TRANK1 ARHGAP20	9.49e-05	182	179	6	6cde859edfe7607bd7ada89d20258413d06f4207
ToppCell	Severe_COVID-19-B_cell-B_cell\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	CR2 ANKRD13A PDLIM1 IGHA1 IGHA2 IGHM	9.78e-05	183	179	6	5634e528001c389efd1e380f01ad40072f60e943
ToppCell	IPF-Lymphoid-B\|IPF / Disease state, Lineage and Cell class	ADAM19 CR2 ANKRD44 IGHA1 IGHA2 IGHM	9.78e-05	183	179	6	e37d2c015c34471a8a54a0299e94b0371e1ada5a
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	ADAM19 CR2 PNPT1 TRANK1 PDLIM1 IGHM	9.78e-05	183	179	6	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	nucseq-Immune-Lymphocytic_B\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAM19 CR2 ANKRD44 IGHA1 IGHA2 IGHM	1.01e-04	184	179	6	911658e7bb499c1bbc8419eec8ff88729bc39a75
ToppCell	CTRL-Lymphoid\|CTRL / Disease state, Lineage and Cell class	ADAM19 CR2 IGHA1 IGHA2 PRF1 IGHM	1.01e-04	184	179	6	26fb2c4e6cb9950c27eb15428e7e74e5abb4397d
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAM19 CR2 ANKRD44 IGHA1 IGHA2 IGHM	1.01e-04	184	179	6	942b58ae7172bb5f97e55b032db9329d161854af
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 CR2 ANKRD44 IGHA1 IGHA2 IGHM	1.01e-04	184	179	6	f81209e6bc01a0140f4487aa8b22eb02fbf0c39c
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi\|lung / Disease (COVID-19 only), tissue and cell type	ADAM19 TERT IGHA1 IGHA2 IGHM KIF14	1.07e-04	186	179	6	66676d9395172de5707e204826a1c9f73b448cca
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 ADAM19 CCDC88B NLRP3 ANKRD44 NBEAL2	1.07e-04	186	179	6	305f1726b8b5add32f1c29c74991ff34f42e0da7
ToppCell	Children_(3_yrs)-Immune-B_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAM19 CR2 ANKRD44 IGHA1 IGHA2 IGHM	1.07e-04	186	179	6	aa576748921a318798b911a611f05319b95e8d5e
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 WASF3 FREM3 NBEAL2 CTNND2 FHIP1A	1.10e-04	187	179	6	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ADARB2 ARHGEF10L MET SLCO4C1 WWC1	1.10e-04	187	179	6	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADAM19 DIPK1B CR2 ZDHHC23 PDLIM1 IGHM	1.10e-04	187	179	6	d01926be1c8846a25fb6706e26b56b808b69f8f0
ToppCell	Control-Lymphoid_B-B_memory\|Control / Disease group, lineage and cell class	ADAM19 ZDHHC23 PDLIM1 IGHA1 IGHA2 IGHM	1.13e-04	188	179	6	ba4245de3bee29118abab57c4fce60b2007a189c
ToppCell	343B-Lymphocytic-ILC-ILC-1\|343B / Donor, Lineage, Cell class and subclass (all cells)	HEATR5A TMEM267 CDK5RAP2 PCNX1 CORO7 HTT	1.13e-04	188	179	6	8f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANKRD13A MET NBEAL2 FBXL2 FHIP1A WWC1	1.13e-04	188	179	6	43a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCell	Severe_COVID-19-B_cell\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	TERT IGLV3-19 IGHA1 IGHA2 IGHM CDC6	1.17e-04	189	179	6	59ce8f15f413557d2059ee6b53ba5957b864cb8e
ToppCell	BAL-Severe-Lymphocyte-B-Plasmablast-Plasmablast-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TERT IGLV3-19 IGHA1 IGHA2 IGHM CDC6	1.17e-04	189	179	6	b0fcbe13a91a4b8dfa507b7a484f45477ef31609
ToppCell	BAL-Severe-Lymphocyte-B-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	TERT IGLV3-19 IGHA1 IGHA2 IGHM CDC6	1.17e-04	189	179	6	d5d25f4151ea96e2d4b3a0e0910e7ff995eaf752
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 MET RIMBP2 CTNND2 FHIP1A WWC1	1.17e-04	189	179	6	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	Severe_COVID-19-B_cell-Plasmablast\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	TERT IGLV3-19 IGHA1 IGHA2 IGHM CDC6	1.17e-04	189	179	6	d7bfefc8c35374c5288807349a76dbb10e84c52b
ToppCell	BAL-Severe-Lymphocyte-B-Plasmablast-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	TERT IGLV3-19 IGHA1 IGHA2 IGHM CDC6	1.17e-04	189	179	6	0f0607642eecc66222d23afe6d77b6872343cb8e
ToppCell	COPD\|World / Disease state, Lineage and Cell class	ADAM19 IGHA1 IGHA2 PRF1 IGHM PCNX1	1.17e-04	189	179	6	53577632683686dc493a5a3fdc01887ec5c320f2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ADARB2 ARHGEF10L MET SLCO4C1 WWC1	1.20e-04	190	179	6	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	BAL-Severe-Lymphocyte-B\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TERT IGLV3-19 IGHA1 IGHA2 IGHM CDC6	1.20e-04	190	179	6	e82fefea5ac03470d10463832d3efd2380895860
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 FBP1 RIMBP2 CTNND2 FHIP1A WWC1	1.20e-04	190	179	6	c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ADARB2 ARHGEF10L MET SLCO4C1 WWC1	1.20e-04	190	179	6	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	BAL-Severe-Lymphocyte-B-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TERT IGLV3-19 IGHA1 IGHA2 IGHM CDC6	1.20e-04	190	179	6	9560722facaf3516936fcbc2a900a405fd85e5d0
ToppCell	BAL-Severe-Lymphocyte-B-Plasmablast-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TERT IGLV3-19 IGHA1 IGHA2 IGHM CDC6	1.20e-04	190	179	6	7fbaf46bf24d46543047582f0d262f3523e28eb4
Drug	Carcinine [56897-53-1]; Up 200; 22uM; MCF7; HT_HG-U133A	MED16 DYNC2H1 HLCS SIPA1 FZR1 MTMR6 BRF1 CPLANE1 CDC25C DDX28	2.95e-06	197	174	10	3242_UP
Drug	Kanamycin A sulfate [25389-94-0]; Down 200; 6.8uM; MCF7; HT_HG-U133A	ADAM19 MED16 HLCS MFSD9 LYST FZR1 MTMR6 NBEAL2 DIAPH2 FBXL2	3.23e-06	199	174	10	3224_DN
Disease	Liver carcinoma	KMT2B ADAMTS13 EZH2 TERT MET PNPT1 SCAP FBP1 CELSR3 MTUS1 GLUL KIF14 CDC6 CDC25C	1.82e-06	507	172	14	C2239176
Disease	Lupus Erythematosus	CR2 C2	3.38e-05	2	172	2	C0409974
Disease	Lupus Vulgaris	CR2 C2	3.38e-05	2	172	2	C0024131
Disease	Cri-du-Chat Syndrome	TERT CTNND2	1.01e-04	3	172	2	C0010314
Disease	neutrophil count	TRERF1 TET2 SPHK2 ADAM19 DYNC2H1 HECTD4 NAIP TERT NLRP3 ANKRD13A MET RSBN1 THADA PDLIM1 SUPT5H NBEAL2 CD101 BTN2A3P HTT PCNT	1.71e-04	1382	172	20	EFO_0004833
Disease	alanine aminotransferase 1 measurement	MED16 C2	2.01e-04	4	172	2	EFO_0802260
Disease	Hernia	PNPT1 THADA HMCN2 AIG1	2.25e-04	51	172	4	HP_0100790
Disease	Aplastic anemia	TERT PRF1	3.34e-04	5	172	2	cv:C0002874
Disease	Lupus Erythematosus, Discoid	CR2 C2	3.34e-04	5	172	2	C0024138
Disease	Aplastic anemia, idiopathic	TERT PRF1	3.34e-04	5	172	2	C0348890
Disease	chronic myelomonocytic leukemia (is_implicated_in)	TET2 EZH2	3.34e-04	5	172	2	DOID:0080188 (is_implicated_in)
Disease	APLASTIC ANEMIA	TERT PRF1	3.34e-04	5	172	2	609135
Disease	Primary Myelofibrosis	TET2 EZH2	4.99e-04	6	172	2	C0001815
Disease	Leukemia, Myelomonocytic, Chronic	TET2 EZH2	4.99e-04	6	172	2	C0023480
Disease	oral squamous cell carcinoma (is_marker_for)	TET2 NAIP EZH2 MET	5.08e-04	63	172	4	DOID:0050866 (is_marker_for)
Disease	Aplastic Anemia	TERT PRF1	6.96e-04	7	172	2	C0002874
Disease	Hypoplastic anemia	TERT PRF1	6.96e-04	7	172	2	C0178416
Disease	Nephronophthisis, familial juvenile	NPHP4 MAPKBP1	6.96e-04	7	172	2	C1855681
Disease	baculoviral IAP repeat-containing protein 5 measurement	MED16 C2	6.96e-04	7	172	2	EFO_0020174
Disease	C-C motif chemokine 1 measurement	MED16 C2	6.96e-04	7	172	2	EFO_0008041
Disease	pancreatic cancer (biomarker_via_orthology)	EZH2 MET	6.96e-04	7	172	2	DOID:1793 (biomarker_via_orthology)
Disease	Colorectal Carcinoma	TET2 ADAM19 ERCC6 OBSCN ADARB2 ARHGEF10L MLH3 BRF1 GNAS CTNND2 FBXL2 SNRNP200	8.92e-04	702	172	12	C0009402
Disease	alpha-2-macroglobulin measurement	TET2 IGHA2	9.24e-04	8	172	2	EFO_0020138
Disease	Developmental delay (disorder)	SZT2 PIGQ PNPT1	1.31e-03	37	172	3	C0424605
Disease	DNA repair protein rad51 homolog 1 measurement	MED16 C2	1.47e-03	10	172	2	EFO_0020330
Disease	stromal interaction molecule 1 measurement	MED16 C2	1.47e-03	10	172	2	EFO_0802093
Disease	Disorder of eye	VAX1 FRAS1 NPHP4 LRP5 CPLANE1 SNRNP200	1.57e-03	212	172	6	C0015397
Disease	coronary artery disease	ANKRD31 TET2 ADAM19 DYNC2H1 WASF3 HECTD4 RNF213 SIPA1 ADARB2 RSBN1 THADA NUS1 C2 CORO7 ARHGAP20 OR56B4	1.73e-03	1194	172	16	EFO_0001645
Disease	hepatocellular carcinoma	GRIK1 TERT C2	1.76e-03	41	172	3	EFO_0000182
Disease	glycerol-3-phosphate dehydrogenase 1-like protein measurement	MED16 C2	1.79e-03	11	172	2	EFO_0801640
Disease	waist-hip ratio	TET2 EFL1 DYNC2H1 HECTD4 ZNF407 TDRG1 ACVR1 SIPA1 OPCML BPTF THADA KIAA1328 PCNX1 MAPKBP1 CORO7 HTT	2.26e-03	1226	172	16	EFO_0004343
Disease	obsolete_red blood cell distribution width	SPHK2 KMT2B KIAA0232 HECTD4 WDR83 ZNF407 SIPA1 EZH2 FREM3 NLRP3 PIGQ FZR1 TMEM267 MCUR1 LRP5 OR51V1 WDFY1	2.34e-03	1347	172	17	EFO_0005192
Disease	aspartate aminotransferase measurement	ANKRD31 MCMBP HECTD4 OBSCN DNAH2 RNF213 OPCML NLRP3 HMCN2 STRN4 ABTB2 ALPK2 MTARC1	2.56e-03	904	172	13	EFO_0004736
Disease	systemic lupus erythematosus (is_marker_for)	ADAMTS13 PRF1 C2	2.61e-03	47	172	3	DOID:9074 (is_marker_for)
Disease	Neuroblastoma	TERT MET GNAS	2.61e-03	47	172	3	C0027819
Disease	mean platelet volume	TET2 ADAM19 COL6A6 PCDHGB1 KIAA0232 EPX TERT NLRP6 RSBN1 TRANK1 BRF1 PDLIM1 GNAS HTT	2.70e-03	1020	172	14	EFO_0004584
Disease	acute myeloid leukemia (is_marker_for)	TET2 EZH2 TERT	2.95e-03	49	172	3	DOID:9119 (is_marker_for)
Disease	Major Depressive Disorder	FREM3 TERT GFAP NTM CTNND2 PCNT	3.10e-03	243	172	6	C1269683
Disease	platelet storage pool deficiency (implicated_via_orthology)	LYST HPS5	3.37e-03	15	172	2	DOID:2223 (implicated_via_orthology)
Disease	nasopharynx carcinoma (is_implicated_in)	TET2 CR2	3.37e-03	15	172	2	DOID:9261 (is_implicated_in)
Disease	lung carcinoma, estrogen-receptor negative breast cancer, ovarian endometrioid carcinoma, colorectal cancer, prostate carcinoma, ovarian serous carcinoma, breast carcinoma, ovarian carcinoma, lung adenocarcinoma, squamous cell lung carcinoma	TET2 DYNC2H1 TERT	3.49e-03	52	172	3	EFO_0000305, EFO_0000571, EFO_0000708, EFO_0001071, EFO_0001075, EFO_0001663, EFO_1000650, EFO_1001515, EFO_1001516, MONDO_0005575
Disease	immature platelet count	KIAA0232 TERT BRF1 GNAS	3.49e-03	106	172	4	EFO_0803544
Disease	primary autosomal recessive microcephaly (is_implicated_in)	KIF14 RRP7A	3.84e-03	16	172	2	DOID:0070296 (is_implicated_in)
Disease	Unipolar Depression	FREM3 TERT GFAP NTM CTNND2 PCNT	4.24e-03	259	172	6	C0041696
Disease	hepatocellular carcinoma (is_implicated_in)	TET2 KMT2B EZH2 TERT MET	4.27e-03	181	172	5	DOID:684 (is_implicated_in)
Disease	Moyamoya Disease	RNF213 PCNT	4.34e-03	17	172	2	C0026654
Disease	Hypogammaglobulinemia	CR2 IGHM	4.34e-03	17	172	2	C0086438
Disease	immature platelet fraction	KIAA0232 BRF1 PDLIM1 GNAS	4.52e-03	114	172	4	EFO_0009187
Disease	Amyotrophic Lateral Sclerosis	SETX GFAP GLE1	4.75e-03	58	172	3	C0002736
Disease	Age-related macular degeneration	ERCC6 C2	4.86e-03	18	172	2	cv:C0242383
Disease	Chronic myeloproliferative disorder	CDC6 PCNT	5.41e-03	19	172	2	C1292778
Disease	psoriasis	SPHK2 ADAM19 GART BPTF ANXA10 C2	5.45e-03	273	172	6	EFO_0000676

Protein segments in the cluster

Peptide	Gene	Start	Entry
RGELCELLETTSESN	NAIP	361	Q13075
SVRNVSCSINDTLLG	BTN2A3P	211	Q96KV6
LNSRLLETFCSEIGT	FAM200B	361	P0CF97
TSGQRQLLLCETLTE	ARHGEF10L	531	Q9HCE6
RSSCGSLRLTVSIEA	CPN2	526	P22792
ICVLTDLSSLLTRGS	AIG1	56	Q9NVV5
LLKQTDECIRGESSS	ARHGEF6	756	Q15052
GTDENCLIEILASRT	ANXA10	106	Q9UJ72
RAQSSLCLRDETLAG	CCDC88B	1376	A6NC98
CLQGTILSENRISRS	ALPK2	1456	Q86TB3
ETELSSVTLSTCRGI	ADAM19	121	Q9H013
ADCLISSNGIISSRL	EFL1	36	Q7Z2Z2
TTLSTDLECGKLIRE	GRIK1	891	P39086
DTVSCLRIVLSIASG	ACVR1	301	Q04771
EELLKSRCSSIGIQD	DLGAP2	706	Q9P1A6
LCSLISGIIRASSES	GLE1	286	Q53GS7
RVLAQEVICLDSSSG	RAD54L2	176	Q9Y4B4
RSGISDEKLLNCLES	DIAPH2	171	O60879
REELGTQLRTCTTLS	DIPK1B	386	Q5VUD6
DLIQGCSESDSSVLR	BPTF	1261	Q12830
ELTTGLELVDSCIRS	CTNND2	116	Q9UQB3
LELVDSCIRSLQESG	CTNND2	121	Q9UQB3
VLDDLTSCTTSLRQI	ERCC6	136	Q03468
TLRVLESSLNCSAGD	ADAMTS13	1226	Q76LX8
LELRSEGLITEKCSS	CDK5RAP2	516	Q96SN8
ADLEIINATTGRRSC	ADARB2	646	Q9NS39
ASGALLCTRDDLRTL	INTS15	361	Q96N11
SGLRRVLDELTLCTT	KRT26	191	Q7Z3Y9
SILSDSQICLLAVEG	LRRC57	196	Q8N9N7
SELCGLSSLRDLNVR	LRCH4	176	O75427
RAIQESLLTSTEGLC	ANKRD13A	526	Q8IZ07
LRNGLDSSTEACSVS	ANKRD31	791	Q8N7Z5
VLDDLTSCTTSLRQI	ERCC6	136	P0DP91
VSLNLQSCSRITDEG	FBXL2	211	Q9UKC9
TSRINLIDLAGSERC	KIF14	596	Q15058
TQSDTLFLDCTIRGL	KIAA0100	516	Q14667
LRSNIVTIGTDSAIC	FRAS1	3286	Q86XX4
LTLTRGCEATESLTQ	LINS1	461	Q8NG48
CRRELSLSAGSLQLE	MCUR1	136	Q96AQ8
RLVLISLTCDGDTLT	MTARC1	111	Q5VT66
GCTDETLLSAIASAL	MBD3	171	O95983
FSTAIGRTCITDLQL	MFSD9	386	Q8NBP5
TVRQGESATLRCTID	NTM	46	Q9P121
ELSATLCELSLGNSA	WWC1	571	Q8IX03
LVNLRGELVTASTTC	MTUS1	961	Q9ULD2
DRTSQVCSLGSLLLD	MTMR6	341	Q9Y217
DLTTLNISGRELCSL	GABPA	211	Q06546
LENASVTLECLASGV	HMCN2	1906	Q8NDA2
RCSSNLVLTGSSERE	C2	176	P06681
SAVLGLSEESLQCRR	MESP2	136	Q0VG99
SGLRNDLAELTTLCL	HPS5	731	Q9UPZ3
IESCDLSGANRLTLE	LRP5	1136	O75197
LTVTESSRGLNLECL	LMTK3	466	Q96Q04
DQSEVKLSVLSSGCR	HLCS	276	P50747
ALASLTLDTSLGCLV	CORO7	251	P57737
RANLTSAIETLCGVD	EIF2B1	46	Q14232
LTSVSSLRGTRECSV	EZH2	71	Q15910
SLRGTRECSVTSDLD	EZH2	76	Q15910
TRARVLSLDSGTVAC	PCNX1	686	Q96RV3
CLRSASDESSGIETL	KIAA0232	116	Q92628
GLSLQESCRLIEALS	MLH3	1371	Q9UHC1
GIIREISLDSCIAQS	OR51V1	96	Q9H2C8
LRRSSSLDTEGCFQT	PCDHGB1	711	Q9Y5G3
LSRISLSRIICDNTG	EPX	666	P11678
LSRIICDNTGITTVS	EPX	671	P11678
LTALRTCELALEGLT	PRF1	236	P14222
LDVDTLASLLSSNGC	NUS1	221	Q96E22
SSRDILLCTDIASRG	DDX28	446	Q9NUL7
LERCNLTALSGESLG	LINGO3	181	P0C6S8
RIDSLGTLSDLSDCE	KMT2B	1736	Q9UMN6
SLLLGAIDSSIVSCR	ANKRD44	821	Q8N8A2
SLTCDLESLRGTNES	GFAP	291	P14136
QESLDISLCSTGSLG	HECTD4	3111	Q9Y4D8
VSDGTRCLLARQSSF	NUDT13	206	Q86X67
LIHGLQDLSITCSES	OOSP4A	16	A0A2R8YFL7
LLASTLQSTLDAGRC	PCNT	1611	O95613
RKSTLQCSSVELDGS	KIAA1328	196	Q86T90
CLDLSNLSSGEITAT	CDC25C	71	P30307
VDVSCVAGQLTRLSL	NPHP4	1236	O75161
SGQVLTSTESLCRLR	MED16	196	Q9Y2X0
QESIEGATATLRCEL	OBSCN	3371	Q5VST9
CGQERTSATLTVRAL	OBSCN	3786	Q5VST9
LGVTSLSCDDRRINS	OR56B2P	191	Q8NGI1
TVRQGESATLRCTID	OPCML	46	Q14982
SNLGVISLACDDITV	OR56B4	186	Q8NH76
ETQCTLGLTALRSDE	PHF10	131	Q8WUB8
RGTGELTQLLNSLCT	FBP1	26	P09467
DSCLLELQGSVRSVD	FAM189B	346	P81408
TSQVTRLCDLSVEGD	FZR1	216	Q9UM11
DIQSGLSDSRSGLCI	DYNC2H1	541	Q8NCM8
CSSGITLTLGNQERD	FHIP1A	446	Q05DH4
ISCTVINRLRDGDST	HTT	1706	P42858
TISNCVREDSGLILL	IGSF22	666	Q8N9C0
SNTDIECSILSRSNG	CD101	691	Q93033
IRNGSCSSDGLLDLV	HEATR5A	1426	Q86XA9
GVDSTVCTALLNRAL	GMPS	246	P49915
ILIGESTLRCTVDSQ	CR2	316	P20023
FSLIGESTIRCTSND	CR2	566	P20023
LNLRESATITCLVTG	IGHM	341	P01871
RRLLCDSGITESSSE	CPLANE1	1756	Q9H799
DLLLGSEANLTCTLT	IGHA1	136	P01876
SEANLTCTLTGLRDA	IGHA1	141	P01876
IFSTLGERECDRSSL	CCDC66	246	A2RUB6
LCEVSLTSSAQGEAR	GOLGA8J	576	A6NMD2
DQLLDTIRSLTIGCS	HAUS7	131	Q99871
VDQSECLSLSGLLEA	CDC6	501	Q99741
SLCNLEESITSAGRD	FAM98B	61	Q52LJ0
SCEETQALALRVILS	LYST	1826	Q99698
LCEVSLTSSAQGEAR	GOLGA8H	576	P0CJ92
LTQRVTSLSLDICEG	MBOAT4	126	Q96T53
LATLCGQESTDTERA	MASP2	86	O00187
ITSSGLLCEFSDRRL	MAPKBP1	251	O60336
VTGRELSSCQLLISQ	KIF5A	621	Q12840
GETLTRARDTICNDL	KLHDC9	276	Q8NEP7
LCLSSEGSEVILATS	HSPB11	6	Q9Y547
LEDLLLGSEANLTCT	IGHA2	121	P01877
NLTCTLTGLRDASGA	IGHA2	131	P01877
ILNTSDCGASSNRLE	CCDC168	3586	Q8NDH2
STLLCQLDRGLLSVT	CELSR3	1811	Q9NYQ7
FLLAARTSCSTGQRE	CELSR3	2701	Q9NYQ7
SGRQSLARLASSICD	DNAH2	2766	Q9P225
DSSGIRSLEELCLQV	SCAP	136	Q12770
TLSVECLGSRLNDIS	DOK4	106	Q8TEW6
CGLQTLSLASVELSE	NLRP6	841	P59044
DILRAISSLNGVSCE	COL6A6	1216	A6NMZ7
RCLSLSAGQTTLSRE	MCMBP	601	Q9BTE3
KGCTDNLTLTVARSE	PDLIM1	71	O00151
CREVSLVTQRSLGDL	NLRP3	261	Q96P20
REGCILDLSDSSVTR	NTMT2	226	Q5VVY1
SGDASQELIVICSTR	FREM3	1911	P0C091
VTEALIRTCLLNETG	GLUL	351	P15104
TRVLLGNESCTLTLS	MET	601	P08581
LSSLVCSNRTLLIDG	ARHGAP20	76	Q9P2F6
GTLSSLRLQCRSQSD	RSBN1	511	Q5VWQ0
ETLLNQLRSGTVACS	SZT2	276	Q5T011
GEATRDSLRVFSSLC	RGL2	371	O15211
VTSRGSSDELQCTLL	RIMBP2	371	O15034
TLGLLCESNRSTEIV	THADA	641	Q6YHU6
AAARGSELCQTALSL	SIGLEC15	96	Q6ZMC9
DSSGSLVQRASCELE	TDRG1	81	Q3Y452
LTLCIGSVVSSELTQ	IGLV3-19	11	P01714
SLETDTLLTKLCGQD	PLEKHA4	361	Q9H4M7
RLEVLGCTLSADSTL	FBXL12	206	Q9NXK8
GCTLSADSTLLAISR	FBXL12	211	Q9NXK8
SDQDLLRCRVLTSGI	GNAS	836	Q5JWF2
EALQATALRTLCTLG	NBEAL2	811	Q6ZNJ1
LCEVSLTSSAQGEAR	GOLGA8M	576	H3BSY2
SACLGLTVALSLLSD	PIGQ	376	Q9BRB3
RTDLTINCLAEGASS	SKIDA1	566	Q1XH10
CDRGIIVSTRLLTDS	SETX	736	Q7Z333
ASTCNTILESLSREG	SIPA1	936	Q96FS4
RDLQLCSETASGVDV	SUPT5H	516	O00267
EAASRADTILCLGSS	SIRT7	256	Q9NRC8
GRDLTSLRNVSCEVD	PNPT1	361	Q8TCS8
RTLEQSLLATCVGSI	ABTB2	326	Q8N961
SLLATCVGSISELSD	ABTB2	331	Q8N961
CVGSISELSDLVSRA	ABTB2	336	Q8N961
TEESLSRLLSTCGLV	RRP7A	71	Q9Y3A4
SRLLSTCGLVQSVEL	RRP7A	76	Q9Y3A4
DTTRLLRSCVQSAVG	RNF213	3531	Q63HN8
LVDCISTTSGTLLRL	STK19	351	P49842
TATLEALCGIAEATQ	XPO4	806	Q9C0E2
TLRGVCSLDAETSSR	SEMA4G	301	Q9NTN9
LDLLSVTLASGSRCF	SPHK2	316	Q9NRA0
LTVSCENRGIISLSE	SLITRK5	61	O94991
ETFTRDACSLLGLSV	RMND5B	266	Q96G75
EAELRLKGSSNTTEC	MEX3A	121	A1L020
LGSLFEDTCVTTRNS	SLCO4C1	201	Q6ZQN7
ALEICGAQRSASELT	TSPYL1	131	Q9H0U9
LGTSTDLRVFLSCLS	RFX8	361	Q6ZV50
GITSELECVTNSTLA	WASF3	21	Q9UPY6
SLFELRTCLQTGTVL	SLC4A5	161	Q9BY07
RTCLQTGTVLLDLDS	SLC4A5	166	Q9BY07
TSLCDTVGALLARQL	TMEM44	71	Q2T9K0
RDGQCTLVSSLDSTL	WDR83	201	Q9BRX9
EVIQSTLDGLLCTSL	GART	311	P22102
LGISDSIRECISSQS	BRF1	421	Q92994
STSLETSIQLCGLIR	ZNRD2	171	O60232
GDRSLSSSQLECLSR	ZDHHC23	201	Q8IYP9
VRCTLSANLVASGEL	SNRNP200	236	O75643
TCSESLCLVQTERSG	ZNF544	306	Q6NX49
SQRLASCSADGTVRI	STRN4	556	Q9NRL3
LIDTGRISEAETLCT	TTC37	1336	Q6PGP7
SSALDALLCAVTELG	ZNF407	1986	Q9C0G0
TGSLCSLEVLITRLS	TRAPPC10	1076	P48553
LESCSVSDLAILLRG	TRANK1	1511	O15050
LLTQTSEECNGILTE	ZNF396	11	Q96N95
LLTEERSRASCFTGL	SMC5	871	Q8IY18
GSTLVCTLTREDNRE	TET2	1391	Q6N021
DGRLCNSRLLSAVSS	TOPBP1	1006	Q92547
LQLTRQLVSCSSDGG	WDFY1	251	Q8IWB7
CGLLLDTRTLEVQSD	TERT	931	O14746
LLQTCSTESLISSLG	TMEM267	11	Q0VDI3
LGTADSVCSRIIQDR	ZNF805	161	Q5CZA5
DSCVSLESKDTLLGR	ZBBX	521	A8MT70
EELSCSGRDTKIQSL	ZBBX	756	A8MT70
SQGDSIRQCILTRDS	ZNF114	141	Q8NC26
ETAATCSVLRLLEQG	VAX1	171	Q5SQQ9
VLLCRSNSIDGSNVT	TRERF1	751	Q96PN7
LCEVSLTSSAQGEAR	GOLGA8IP	576	A6NC78