Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	RRM	ACIN1 RBM19 EIF4B	2.02e-03	217	22	3	SM00360
Domain	RRM_dom	ACIN1 RBM19 EIF4B	2.30e-03	227	22	3	IPR000504
Domain	-	ACIN1 RBM19 EIF4B	2.82e-03	244	22	3	3.30.70.330
Domain	Nucleotide-bd_a/b_plait	ACIN1 RBM19 EIF4B	3.30e-03	258	22	3	IPR012677
Pubmed	Rapgef2, a guanine nucleotide exchange factor for Rap1 small GTPases, plays a crucial role in adherence junction (AJ) formation in radial glial cells through ERK-mediated upregulation of the AJ-constituent protein expression.	MAPK1 RAPGEF2	1.37e-06	3	24	2	28917843
Pubmed	Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2.	TCHHL1 MAPK1	2.05e-05	10	24	2	25547114
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	DAAM2 PLEKHM1 RAPGEF2	5.02e-05	104	24	3	9205841
Pubmed	Isthmin-1 (Ism1) modulates renal branching morphogenesis and mesenchyme condensation during early kidney development.	MAPK1 ISM1	7.75e-05	19	24	2	37185772
Pubmed	DAAM1 and DAAM2 are co-required for myocardial maturation and sarcomere assembly.	DAAM2 MAPK1	1.47e-04	26	24	2	26526197
Pubmed	iRhom2 mutation leads to aberrant hair follicle differentiation in mice.	DAAM2 MAPK1	1.96e-04	30	24	2	25546423
Pubmed	The endolysosomal adaptor PLEKHM1 is a direct target for both mTOR and MAPK pathways.	PLEKHM1 MAPK1	2.38e-04	33	24	2	33452816
Pubmed	Identification of NPM-ALK interacting proteins by tandem mass spectrometry.	EIF4B MAPK1	4.84e-04	47	24	2	14968112
GeneFamily	RNA binding motif containing	RBM19 EIF4B	9.89e-03	213	13	2	725
Disease	interleukin-6 measurement	BTBD7 MAPK1	2.59e-03	112	20	2	EFO_0004810
Disease	asthma, Eczema, allergic rhinitis	TCHHL1 LAYN	3.02e-03	121	20	2	EFO_0005854, HP_0000964, MONDO_0004979
Disease	Eczema, allergic rhinitis	TCHHL1 LAYN	9.21e-03	215	20	2	EFO_0005854, HP_0000964
Disease	asthma	MED17 TCHHL1 LAYN	1.36e-02	751	20	3	MONDO_0004979
Disease	Cleft palate, cleft lip	ABCA13 EIF4B	1.51e-02	279	20	2	EFO_0003959, HP_0000175

Protein segments in the cluster

Peptide	Gene	Start	Entry
RTALHGVKWPQSNPK	ACIN1	1066	Q9UKV3
VKNPSWKFHPQNLPA	ABCA13	3501	Q86UQ4
PEWKPHQKPRTLSKS	CCDC27	81	Q2M243
PRAWSKHAQKPSQPK	RBM19	86	Q9Y4C8
KRVPQPSHPLKSFNW	DAAM2	596	Q86T65
SLPHKNKVPWNRLFP	MAPK1	266	P28482
HFRPPKTKPQRKGSW	LOXL4	291	Q96JB6
WTGRKKHELKPNNPT	KIAA0895	351	Q8NCT3
QPDPSTKKQHTIWPS	LAYN	266	Q6UX15
LPKSKPGSPHWQTKL	MED17	281	Q9NVC6
TPSRKPLPKRKNTWN	EDDM13	106	A0A1B0GTR0
LKAGWKQRPPSQHPS	BTBD7	776	Q9P203
SSPKEWRNSKKQLPP	KIAA1210	1316	Q9ULL0
WRNSKKQLPPKHSSQ	KIAA1210	1321	Q9ULL0
KDQHPENKPSWSVPS	ISM1	141	B1AKI9
SWDPKSPFKQKPAQR	LRRC72	206	A6NJI9
APPPKENAWVKRSSN	EIF4B	476	P23588
KKSAHQKPLPQPVFW	PLEKHM1	76	Q9Y4G2
KAPKRKQAFHWQPPL	NKTR	1006	P30414
IPFQGKPKPQATWTH	MYBPH	196	Q13203
IKGSHLKNWAANRPP	SYT14P1	71	Q58G82
NRVPLHKPTDWQKKI	FAM162A	56	Q96A26
HPTSSRPVNKPQWHK	RAPGEF2	1456	Q9Y4G8
RPVNKPQWHKPNESD	RAPGEF2	1461	Q9Y4G8
KSHGVKNSPWKHQPQ	TEX13C	916	A0A0J9YWL9
SPKPPHTLSRKQWRN	RRP8	176	O43159
QKSPAKKEHNSSVPW	TCHHL1	761	Q5QJ38