Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	cardiac muscle thin filament assembly	NRAP NEB	4.01e-05	3	76	2	GO:0071691
GeneOntologyBiologicalProcess	regulation of SA node cell action potential	ANK2 RYR2	4.01e-05	3	76	2	GO:0098907
GeneOntologyBiologicalProcess	mRNA splice site recognition	SETX PSIP1 CELF1 CELF2	4.03e-05	52	76	4	GO:0006376
GeneOntologyBiologicalProcess	regulation of atrial cardiac muscle cell action potential	ANK2 RYR2	8.00e-05	4	76	2	GO:0098910
GeneOntologyBiologicalProcess	regulation of locomotor rhythm	MTOR ZFHX3	8.00e-05	4	76	2	GO:1904059
GeneOntologyBiologicalProcess	regulation of AV node cell action potential	ANK2 RYR2	1.33e-04	5	76	2	GO:0098904
GeneOntologyBiologicalProcess	wound healing, spreading of epidermal cells	ARHGAP24 MTOR PHLDB2	1.47e-04	28	76	3	GO:0035313
GeneOntologyCellularComponent	Z disc	AKAP4 NRAP ANK2 XIRP2 NEB RYR2	1.85e-05	151	76	6	GO:0030018
GeneOntologyCellularComponent	I band	AKAP4 NRAP ANK2 XIRP2 NEB RYR2	3.16e-05	166	76	6	GO:0031674
GeneOntologyCellularComponent	sarcomere	AKAP4 NRAP ANK2 XIRP2 NEB RYR2	2.93e-04	249	76	6	GO:0030017
GeneOntologyCellularComponent	Flemming body	KIF23 CELF2 BIRC6	3.02e-04	36	76	3	GO:0090543
GeneOntologyCellularComponent	myofibril	AKAP4 NRAP ANK2 XIRP2 NEB RYR2	4.78e-04	273	76	6	GO:0030016
GeneOntologyCellularComponent	contractile muscle fiber	AKAP4 NRAP ANK2 XIRP2 NEB RYR2	6.56e-04	290	76	6	GO:0043292
GeneOntologyCellularComponent	autophagosome	LRRK2 RAB2B RB1CC1 RAB2A	9.34e-04	119	76	4	GO:0005776
GeneOntologyCellularComponent	autophagosome membrane	RAB2B RB1CC1 RAB2A	1.17e-03	57	76	3	GO:0000421
Domain	NEBU	NRAP NEB	9.24e-05	4	74	2	SM00227
Domain	Nebulin	NRAP NEB	9.24e-05	4	74	2	PF00880
Domain	Nebulin	NRAP NEB	9.24e-05	4	74	2	IPR013998
Domain	NEBULIN	NRAP NEB	9.24e-05	4	74	2	PS51216
Domain	Nebulin_repeat	NRAP NEB	9.24e-05	4	74	2	IPR000900
Domain	Hud_Sxl_RNA	CELF1 CELF2	6.83e-04	10	74	2	IPR002343
Domain	ATPase_dyneun-rel_AAA	MDN1 DNAH9	1.37e-03	14	74	2	IPR011704
Domain	AAA_5	MDN1 DNAH9	1.37e-03	14	74	2	PF07728
Domain	P-loop_NTPase	KIF23 SETX SAMD9 MDN1 LRRK2 RAB2B KIF3C DDX60L RAB2A DNAH9	1.82e-03	848	74	10	IPR027417
Domain	RCC1	RPGR HERC4	2.81e-03	20	74	2	PF00415
Domain	RCC1_1	RPGR HERC4	3.10e-03	21	74	2	PS00625
Domain	RCC1_2	RPGR HERC4	3.10e-03	21	74	2	PS00626
Domain	RCC1_3	RPGR HERC4	3.10e-03	21	74	2	PS50012
Domain	Reg_chr_condens	RPGR HERC4	3.40e-03	22	74	2	IPR000408
Domain	-	RPGR HERC4	3.40e-03	22	74	2	2.130.10.30
Domain	RCC1/BLIP-II	RPGR HERC4	3.71e-03	23	74	2	IPR009091
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	EPS15 KIF23 SETX LRRK2 PDS5A ZFHX3 RPGR BIRC6 GOLGA3 RYR2 DMXL1	1.29e-06	777	78	11	35844135
Pubmed	Molecular cloning and characterization of a novel human Rab ( Rab2B) gene.	RAB2B RAB2A	4.97e-06	2	78	2	12376746
Pubmed	Diversity and conservation of CELF1 and CELF2 RNA and protein expression patterns during embryonic development.	CELF1 CELF2	4.97e-06	2	78	2	23468433
Pubmed	Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy.	RAB2B RAB2A	4.97e-06	2	78	2	28063257
Pubmed	Isolation and expression of Napor/CUG-BP2 in embryo development.	CELF1 CELF2	4.97e-06	2	78	2	12763013
Pubmed	Expression of a dominant negative CELF protein in vivo leads to altered muscle organization, fiber size, and subtype.	CELF1 CELF2	4.97e-06	2	78	2	21541285
Pubmed	Loss-of-function missense variant of AKAP4 induced male infertility through reduced interaction with QRICH2 during sperm flagella development.	AKAP4 QRICH2	4.97e-06	2	78	2	34415320
Pubmed	Diminished DYRK2 sensitizes hormone receptor-positive breast cancer to everolimus by the escape from degrading mTOR.	MTOR DYRK2	4.97e-06	2	78	2	27746162
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	EPS15 KIF23 ARHGAP24 MDN1 ANK2 MTOR ARHGEF12 RAB2A UNC79 GOLGA3 PHLDB2	9.92e-06	963	78	11	28671696
Pubmed	A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.	ANK2 CELF1 CELF2 ADGRF5	1.04e-05	60	78	4	19075228
Pubmed	REV-ERBα Regulates CYP7A1 Through Repression of Liver Receptor Homolog-1.	CYP7A1 NR1D2	1.49e-05	3	78	2	29237721
Pubmed	Postmortem genetic analysis of sudden unexplained death syndrome under 50 years of age: A next-generation sequencing study.	ANK2 RYR2	1.49e-05	3	78	2	27005929
Pubmed	Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.	ARHGEF12 PLXNB2	1.49e-05	3	78	2	26627240
Pubmed	Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus.	SOX5 FOXD3 BAZ1B ZFHX3	2.80e-05	77	78	4	21525287
Pubmed	ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy.	MTOR RB1CC1	2.97e-05	4	78	2	19258318
Pubmed	FAM71F1 binds to RAB2A and RAB2B and is essential for acrosome formation and male fertility in mice.	RAB2B RAB2A	2.97e-05	4	78	2	34714330
Pubmed	Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling.	XIRP2 NEB	2.97e-05	4	78	2	23985323
Pubmed	mTORC1 phosphorylates the ULK1-mAtg13-FIP200 autophagy regulatory complex.	MTOR RB1CC1	2.97e-05	4	78	2	19690328
Pubmed	Commensal bacteria direct selective cargo sorting to promote symbiosis.	LRRK2 RAB2A	2.97e-05	4	78	2	26237551
Pubmed	TOR-mediated Ypt1 phosphorylation regulates autophagy initiation complex assembly.	MTOR RB1CC1	2.97e-05	4	78	2	37635626
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	SETX MDN1 PSIP1 POLA1 PDS5A ZZEF1 FAM186B BIRC6 QRICH2	4.02e-05	736	78	9	29676528
Pubmed	Dynamic balance between activation and repression regulates pre-mRNA alternative splicing during heart development.	CELF1 CELF2	4.94e-05	5	78	2	15830352
Pubmed	Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.	MTOR RB1CC1	4.94e-05	5	78	2	19211835
Pubmed	Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF.	ARHGEF12 PLXNB2	4.94e-05	5	78	2	12183458
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	KIF23 MTOR SAMD4B HAT1 PHLDB2	7.05e-05	190	78	5	15161933
Pubmed	The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing.	CELF1 CELF2	7.40e-05	6	78	2	11158314
Pubmed	A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator.	CELF1 CELF2	7.40e-05	6	78	2	10893231
Pubmed	ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery.	MTOR RB1CC1	7.40e-05	6	78	2	19225151
Pubmed	MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1.	CELF1 CELF2	7.40e-05	6	78	2	19720736
Pubmed	Dysregulation of NRAP degradation by KLHL41 contributes to pathophysiology in nemaline myopathy.	NRAP NEB	7.40e-05	6	78	2	30986853
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	SETX PSIP1 CELF1 PDS5A RB1CC1 BIRC6 UNC79	8.98e-05	469	78	7	27634302
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	MDN1 ARHGEF12 PLXNB2 DNAH9	9.08e-05	104	78	4	9205841
Pubmed	Exome sequencing supports a de novo mutational paradigm for schizophrenia.	CELF2 MTOR RB1CC1	1.01e-04	40	78	3	21822266
Pubmed	Small GTPase Rab2B and Its Specific Binding Protein Golgi-associated Rab2B Interactor-like 4 (GARI-L4) Regulate Golgi Morphology.	RAB2B RAB2A	1.04e-04	7	78	2	26209634
Pubmed	A single MIU motif of MINDY-1 recognizes K48-linked polyubiquitin chains.	EPS15 MINDY2	1.04e-04	7	78	2	28082312
Pubmed	miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification.	CELF1 CELF2	1.04e-04	7	78	2	27512039
Pubmed	Age of onset of RNA toxicity influences phenotypic severity: evidence from an inducible mouse model of myotonic dystrophy (DM1).	NRAP CELF1	1.04e-04	7	78	2	24039817
Pubmed	AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.	MTOR RB1CC1	1.04e-04	7	78	2	21258367
Pubmed	mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.	MTOR RB1CC1	1.38e-04	8	78	2	23524951
Pubmed	The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: subserving RPGR function and participating in disk morphogenesis.	RP1 RPGR	1.38e-04	8	78	2	12651948
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	GPR180 KIF23 SETX PSIP1 PDS5A RB1CC1 RAB2A PLXNB2 BIRC6 HERC4 SCARA3	1.46e-04	1297	78	11	33545068
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	KNTC1 SETX PSIP1 CELF1 CELF2 HAT1 PDS5A IKZF1 RAB2A CCDC7	1.76e-04	1103	78	10	34189442
Pubmed	Dynamic transcriptome changes during adipose tissue energy expenditure reveal critical roles for long noncoding RNA regulators.	CELF1 CELF2	1.77e-04	9	78	2	28763438
Pubmed	RUTBC1 protein, a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.	RAB2B RAB2A	1.77e-04	9	78	2	21808068
Pubmed	Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.	XIRP2 LRRK2 STAC	2.09e-04	51	78	3	24510904
Pubmed	SPATA7 maintains a novel photoreceptor-specific zone in the distal connecting cilium.	RP1 RPGR	2.70e-04	11	78	2	29899041
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	NEK3 MDN1 MTOR RAB2B HAT1 PDS5A	2.85e-04	400	78	6	35013556
Pubmed	Genome-wide association study of PR interval.	SOX5 ARHGAP24	3.23e-04	12	78	2	20062060
Pubmed	Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology.	ARHGEF12 PLXNB2	3.23e-04	12	78	2	12123608
Pubmed	Final stages of cytokinesis and midbody ring formation are controlled by BRUCE.	KIF23 BIRC6	3.23e-04	12	78	2	18329369
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	KNTC1 KIF23 MDN1 PSIP1 MTOR POLA1 BAZ1B HAT1 PDS5A KIF3C RAB2A	3.29e-04	1425	78	11	30948266
Pubmed	Identification of host proteins required for HIV infection through a functional genomic screen.	MDN1 ARHGEF12 KIF3C RAB2A DMXL1	3.74e-04	272	78	5	18187620
Pubmed	ULK1 inhibits the kinase activity of mTORC1 and cell proliferation.	MTOR RB1CC1	3.81e-04	13	78	2	21795849
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	KIF23 SETX PSIP1 POLA1 BAZ1B HAT1 PDS5A	4.36e-04	608	78	7	36089195
Pubmed	Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions.	CELF1 CELF2	4.44e-04	14	78	2	28826478
Pubmed	Network organization of the human autophagy system.	KIF23 XIRP2 MTOR HAT1 RB1CC1 GOLGA3	4.55e-04	437	78	6	20562859
Pubmed	Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress.	PSIP1 KIAA0825 BAZ1B PDS5A	4.61e-04	159	78	4	22751105
Pubmed	Genetic dissection of plexin signaling in vivo.	ARHGEF12 PLXNB2	5.12e-04	15	78	2	24469813
Pubmed	Huntingtin functions as a scaffold for selective macroautophagy.	MTOR RB1CC1	5.12e-04	15	78	2	25686248
Pubmed	Negative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survival.	RP1 RPGR	5.12e-04	15	78	2	21148103
Pubmed	Identification of potential protein interactors of Lrrk2.	MDN1 LRRK2	5.12e-04	15	78	2	17400507
Pubmed	Germline genomic variants associated with childhood acute lymphoblastic leukemia.	IKZF1 RYR2	5.12e-04	15	78	2	19684603
Pubmed	A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.	MDN1 MTOR POLA1 RAB2A GOLGA3	5.66e-04	298	78	5	32353859
Pubmed	Unpackaging the genetics of mammalian fertility: strategies to identify the "reproductive genome".	SETX GOLGA3	5.84e-04	16	78	2	29878059
Pubmed	KLHL40 deficiency destabilizes thin filament proteins and promotes nemaline myopathy.	NRAP NEB	5.84e-04	16	78	2	24960163
Pubmed	Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy.	NRAP CELF1	5.84e-04	16	78	2	16717059
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	KIF23 MDN1 MTOR POLA1 BAZ1B PDS5A BIRC6	6.65e-04	653	78	7	22586326
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KIF23 SETX MDN1 MTOR SAMD4B PABIR2 PHLDB2 DYRK2	6.95e-04	861	78	8	36931259
Pubmed	Proteomics characterization of abundant Golgi membrane proteins.	RAB2A GOLGA3	8.28e-04	19	78	2	11042173
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	MDN1 KIAA0825 XIRP2 CROCC2 RP1 NEB	8.90e-04	497	78	6	36774506
Pubmed	A comprehensive resource of interacting protein regions for refining human transcription factor networks.	ANK2 BAZ1B RAB2A RYR2	9.16e-04	191	78	4	20195357
Pubmed	MURF-1 and MURF-2 target a specific subset of myofibrillar proteins redundantly: towards understanding MURF-dependent muscle ubiquitination.	NRAP NEB	9.19e-04	20	78	2	15967462
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	EPS15 KIF23 SETX SAMD4B PABIR2 PHLDB2	9.47e-04	503	78	6	16964243
Pubmed	Tagging genes with cassette-exchange sites.	ARHGEF12 BAZ1B RPGR BIRC6 DMXL1	9.56e-04	335	78	5	15741177
Pubmed	Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways.	EVI5 RAB2A	1.01e-03	21	78	2	17562788
Pubmed	Inactivation of mTORC1 in the developing brain causes microcephaly and affects gliogenesis.	SOX5 MTOR	1.01e-03	21	78	2	23637172
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	MDN1 PSIP1 BAZ1B IKZF1 GOLGA3	1.02e-03	340	78	5	29478914
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	PSIP1 CELF1 POLA1 PDS5A RAB2A	1.02e-03	340	78	5	24332808
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	FOXD3 LRRK2 HAT1 NEB MINDY2 FAM186B	1.05e-03	513	78	6	25798074
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	SOX5 FOXD3 BAZ1B ZFHX3 IKZF1 BIRC6 NR1D2	1.07e-03	709	78	7	22988430
Pubmed	Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain.	EPS15 ARHGEF12	1.11e-03	22	78	2	26950368
Pubmed	Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors.	PDS5A RB1CC1 BIRC6 CCDC144A DYRK2	1.30e-03	359	78	5	35559673
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	KIF23 ARHGEF12 DNAH9 SCARA3 PHLDB2	1.33e-03	361	78	5	26167880
Pubmed	A chemical tool for blue light-inducible proximity photo-crosslinking in live cells.	MTOR GOLGA3	1.44e-03	25	78	2	35211260
Pubmed	Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.	ARHGAP24 NRAP ADGRF5 FAM186B QRICH2 PABIR2 ZNF541	1.48e-03	750	78	7	11230166
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	EVI5 ANK2 CELF2 POLA1 LRRK2 PLXNB2 PABIR2 DMXL1 DYRK2	1.58e-03	1215	78	9	15146197
Pubmed	Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome.	NEB RYR2	1.68e-03	27	78	2	18468998
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KIF23 MDN1 PSIP1 SAMD4B PARG BAZ1B PHLDB2	1.77e-03	774	78	7	15302935
Pubmed	Specification of jaw identity by the Hand2 transcription factor.	ZFHX3 RB1CC1	1.81e-03	28	78	2	27329940
Pubmed	Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation.	MTOR RP1	1.81e-03	28	78	2	32744119
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	EVI5 COL24A1 EPS15 NEK3 MDN1 MTOR CRACDL BAZ1B PLXNB2	1.84e-03	1242	78	9	30973865
Pubmed	Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.	KIF23 PSIP1 PHLDB2	1.87e-03	108	78	3	19531213
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	TSPAN12 RP1 RPGR RB1CC1	1.90e-03	233	78	4	32290105
Pubmed	Structure and evolution of the Smith-Magenis syndrome repeat gene clusters, SMS-REPs.	CCDC144CP CCDC144A	1.94e-03	29	78	2	11997339
Interaction	H3C1 interactions	KIF23 ANK2 PSIP1 XIRP2 POLA1 LRRK2 BAZ1B HAT1 PDS5A ZFHX3 NEB ZZEF1 DNAH9 EZHIP	7.00e-06	901	77	14	int:H3C1
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	ARHGAP24 MDN1 ANK2 CELF1 CELF2 LRRK2 ARHGEF12 ZFHX3 KIF3C RB1CC1 NEB UNC79 GOLGA3 RYR2 CCDC144A DYRK2	1.33e-07	1106	78	16	M39071
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	EVI5 EPS15 KIF23 SETX MDN1 PARG BAZ1B HAT1 PDS5A ZFHX3 RPGR RB1CC1 ZZEF1 HERC4	2.08e-07	856	78	14	M4500
Coexpression	ONKEN_UVEAL_MELANOMA_UP	NEK3 ANK2 CELF2 POLA1 BAZ1B PDS5A RPGR RB1CC1 RAB2A VCPKMT DMXL1	2.15e-05	790	78	11	M12490
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000	KNTC1 NEK3 SETX MDN1 MTOR POLA1 PARG HAT1 NR1D2	2.61e-06	333	75	9	gudmap_dev gonad_e13.5_M_GermCell_Oct_k1_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	KNTC1 NEK3 KIF23 MDN1 MTOR POLA1 PARG HAT1 NR1D2	5.02e-06	361	75	9	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	KNTC1 NEK3 KIF23 SETX MDN1 MTOR POLA1 PARG HAT1 CCDC172 RPGR NR1D2 DMXL1	5.34e-06	820	75	13	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#1_top-relative-expression-ranked_500	EPS15 CCDC172 BIRC6 RYR2 ZNF541 DMXL1	7.95e-06	134	75	6	gudmap_developingGonad_e18.5_ovary_500_k1
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#3_top-relative-expression-ranked_500	CCDC172 RPGR BIRC6 RYR2 DMXL1	8.83e-06	79	75	5	gudmap_developingGonad_P2_ovary_500_k3
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1	KIF23 SETX POLA1 PARG BAZ1B PDS5A EFCAB14 PABIR2 DMXL1	4.00e-05	469	75	9	Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	KNTC1 NEK3 MDN1 POLA1 PARG HAT1 NR1D2	4.30e-05	266	75	7	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k2_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_500	EPS15 CCDC172 RPGR NEB BIRC6 RYR2 ZNF541 DMXL1	6.59e-05	387	75	8	gudmap_developingGonad_e18.5_ovary_500
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#5_top-relative-expression-ranked_1000	SOX5 EPS15 RPGR RYR2 ZNF541 DMXL1	1.63e-04	230	75	6	gudmap_developingGonad_e18.5_ovary_1000_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_200	SOX5 SETX BAZ1B RYR2	1.68e-04	78	75	4	gudmap_developingLowerUrinaryTract_e14.5_ bladder_200_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#3_top-relative-expression-ranked_100	SOX5 BAZ1B RYR2	2.34e-04	34	75	3	gudmap_developingLowerUrinaryTract_e14.5_ bladder_100_k3
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#4_top-relative-expression-ranked_1000	CCDC172 RPGR BIRC6 RYR2 DMXL1	3.22e-04	168	75	5	gudmap_developingGonad_P2_ovary_1000_k4
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	SOX5 EPS15 HAT1 CCDC172 RPGR RB1CC1 BIRC6 RYR2 ZNF541 DMXL1	3.88e-04	776	75	10	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000	SOX5 EPS15 CCDC172 RPGR RB1CC1 NEB BIRC6 RYR2 ZNF541 DMXL1	3.96e-04	778	75	10	gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	SOX5 EVI5 SETX MDN1 ANK2 PSIP1 POLA1 BAZ1B HAT1 PDS5A ZFHX3 EFCAB14 RPGR	4.21e-04	1257	75	13	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL24A1 XIRP2 CYP7A1 NEB DNAH9 UNC79 RYR2	3.53e-08	184	78	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL24A1 XIRP2 CYP7A1 NEB DNAH9 UNC79 RYR2	3.53e-08	184	78	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL24A1 XIRP2 CYP7A1 NEB DNAH9 UNC79 RYR2	3.53e-08	184	78	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	NRAP ANK2 XIRP2 ARHGEF12 DDX60L RYR2 PHLDB2	4.40e-08	190	78	7	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	NRAP ANK2 XIRP2 ARHGEF12 RYR2 PHLDB2	1.01e-06	189	78	6	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	SOX5 CRACDL ARHGEF12 ADGRF5 RP1 DNAH9	1.22e-06	195	78	6	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	SOX5 CRACDL ARHGEF12 ADGRF5 RP1 DNAH9	1.22e-06	195	78	6	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TSPAN12 SETX PSIP1 ARHGEF12 ADGRF5 MINDY2	1.41e-06	200	78	6	b70b7adb7c187e6253c7f0bb4c1f09c85ef7142c
ToppCell	LA-15._Ventricular_Cardiomyocyte_III\|LA / Chamber and Cluster_Paper	TSPAN12 NRAP XIRP2 KIF3C RYR2	6.06e-06	147	78	5	8970eb6b82589f39439c61a57d999661ec8342de
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL24A1 RP1 DNAH9 UNC79 RYR2	1.19e-05	169	78	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	NRAP XIRP2 IKZF1 DDX60L RYR2	1.23e-05	170	78	5	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP XIRP2 RP1 NEB RYR2	1.30e-05	172	78	5	ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRAP XIRP2 RP1 NEB RYR2	1.30e-05	172	78	5	bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP ANK2 XIRP2 DDX60L RYR2	1.45e-05	176	78	5	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEK3 SETX TMCC2 ADGRF5 PHLDB2	1.66e-05	181	78	5	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SETX PARG BAZ1B PDS5A BIRC6	1.80e-05	184	78	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	NRAP ANK2 XIRP2 ANKRD34C RYR2	1.84e-05	185	78	5	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SOX5 COL24A1 ZFHX3 SCARA3 RYR2	2.04e-05	189	78	5	7ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCell	droplet-Lung-LUNG-30m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN12 TMCC2 ARHGEF12 ADGRF5 PHLDB2	2.04e-05	189	78	5	25db316f66cee53774bb2b286cc457b37353356c
ToppCell	droplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN12 TMCC2 ARHGEF12 ADGRF5 PHLDB2	2.10e-05	190	78	5	e64b191f928935484e2c993d7f8af0572a617a3a
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SOX5 COL24A1 ZFHX3 SCARA3 RYR2	2.15e-05	191	78	5	08042952431ca1a6fd7dfc13f36eb28643979598
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SOX5 ANK2 ZFHX3 SCARA3 RYR2	2.15e-05	191	78	5	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SOX5 COL24A1 ZFHX3 SCARA3 RYR2	2.20e-05	192	78	5	992d08092edbc68c47b945deb8708379738c239a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL24A1 ARHGAP24 ANK2 RP1 NEB	2.20e-05	192	78	5	ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	SOX5 CROCC2 CRACDL RP1 DNAH9	2.37e-05	195	78	5	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN12 TMCC2 ARHGEF12 ADGRF5 PHLDB2	2.37e-05	195	78	5	52b2bbf12e5f86c493f6634697aeb23a68cc916d
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN12 TMCC2 ARHGEF12 ADGRF5 PHLDB2	2.37e-05	195	78	5	e5f14f6015ea5e6fa065f906ad22157e3de15c68
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	COL24A1 CELF2 CRACDL IKZF1 STAC	2.37e-05	195	78	5	d70b49f6b9c6c4422adb2936c837a1af7569fb0a
ToppCell	Control-PLT_4\|Control / Disease Group and Platelet Clusters	SETX CELF2 XIRP2 RB1CC1 RYR2	2.55e-05	198	78	5	387fd3037fd52e4d4c42de0588767e58af228b59
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	SOX5 ANK2 CELF2 ARHGEF12 RYR2	2.61e-05	199	78	5	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	SOX5 ANK2 CELF2 ARHGEF12 RYR2	2.61e-05	199	78	5	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TSPAN12 SETX ARHGEF12 ADGRF5 MINDY2	2.68e-05	200	78	5	bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCell	Control_saline-Endothelial-Endothelial-Alv_Gen_Intermediate\|Control_saline / Treatment groups by lineage, cell group, cell type	TSPAN12 SETX ARHGEF12 ADGRF5 MINDY2	2.68e-05	200	78	5	041a34080120c9f613373c20dcc366292f558040
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TSPAN12 SETX ARHGEF12 ADGRF5 DDX60L	2.68e-05	200	78	5	89821a264e872ed53e08e9d3609d5cc5c314503e
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TSPAN12 SETX ARHGEF12 ADGRF5 MINDY2	2.68e-05	200	78	5	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SETX SAMD9 CELF2 DDX60L BIRC6	2.68e-05	200	78	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TSPAN12 SETX ARHGEF12 ADGRF5 MINDY2	2.68e-05	200	78	5	66f7e8ee63c828f17468e79a4b816346b33e8980
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TSPAN12 SETX ARHGEF12 ADGRF5 MINDY2	2.68e-05	200	78	5	b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TSPAN12 SETX ARHGEF12 ADGRF5 MINDY2	2.68e-05	200	78	5	7034f57e282982c19c13ee8ab78eabaffa069e30
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TSPAN12 SETX ARHGEF12 ADGRF5 MINDY2	2.68e-05	200	78	5	89a6da2bdedc6b1ad0675c8753bf2b763a99af6a
ToppCell	Control_saline-Endothelial-Endothelial-Alv_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	TSPAN12 SETX ARHGEF12 ADGRF5 MINDY2	2.68e-05	200	78	5	abf4ba5fcb54cdeada0da1a8b956a30aa47679e4
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	TSPAN12 SETX ARHGEF12 ADGRF5 MINDY2	2.68e-05	200	78	5	432384faeade8e609154fab3d96c955a8ec868dd
ToppCell	BAL-Severe-cDC_6\|Severe / Compartment, Disease Groups and Clusters	KNTC1 KIF23 UNC79 NR1D2	8.04e-05	130	78	4	4104d1e10609331b67db3b85c63537aec58b1713
ToppCell	Mild/Remission-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SOX5 ANK2 LRRK2 NEB	9.58e-05	136	78	4	1b3c6edcbe0eb674d2d9c838e83ebe2b93e3eec1
ToppCell	LA-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	NRAP XIRP2 KIF3C RYR2	1.04e-04	139	78	4	9e2a84d5ed7232b70eadbba754d9ca13f2d50fe9
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Necab1_(MGE-derived_cortical_interneurons--basket_cells)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	RP1 CCDC172 EZHIP	1.23e-04	55	78	3	ed871246b0ada07e8fe87a68584c06986977d0bd
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Necab1_(MGE-derived_cortical_interneurons--basket_cells)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	RP1 CCDC172 EZHIP	1.23e-04	55	78	3	51a76e6cb45976ce99a41fb6cd5b94c632ec7c5b
ToppCell	10x5'-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3\|bone_marrow / Manually curated celltypes from each tissue	KIF23 ZNF713 CRACDL STAC	1.59e-04	155	78	4	83430a64c2cb5ad29caa3dacba76c28dd204ac40
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SOX5 ARHGAP24 ANK2 NEB	1.62e-04	156	78	4	d81e78bec5c8a3f3ec9e1447ebab2c5805b815eb
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL24A1 DNAH9 RYR2 CCDC7	1.79e-04	160	78	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL24A1 DNAH9 RYR2 CCDC7	1.79e-04	160	78	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	PND01-03-samps\|World / Age Group, Lineage, Cell class and subclass	MDN1 TMCC2 ADGRF5 BIRC6	1.83e-04	161	78	4	1973b112d8d67aacc02751797d0148e7b53bfa66
ToppCell	390C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SOX5 ADGRF5 UNC79 CCDC144A	1.88e-04	162	78	4	45be019b50e3727fc9d3fad2ff78e74e4f2d746b
ToppCell	390C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SOX5 ADGRF5 UNC79 CCDC144A	1.88e-04	162	78	4	fbb0cc2b1434a340dc35058b77c73ea61004c252
ToppCell	Ciliated_cells-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	ZNF713 TMCC2 RP1 DNAH9	2.06e-04	166	78	4	4b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLA1 HAT1 NEB VCPKMT	2.11e-04	167	78	4	859dfe0764cb69de27e79e1c1aa65f9d538f79ea
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NRAP XIRP2 NEB FAM186B	2.11e-04	167	78	4	d78356bf0c473816dbabaee51984940bd822f84e
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL24A1 ANK2 XIRP2 SCARA3	2.11e-04	167	78	4	fe3338f99f94c0dac37e3d649dfdce82e4a56022
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FOXD3 ARHGAP24 ANK2 RPGR	2.16e-04	168	78	4	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	Int-URO-Lymphocyte-B-B_intermediate\|Int-URO / Disease, Lineage and Cell Type	TSPAN12 ARHGAP24 ANK2 NEB	2.16e-04	168	78	4	5b3fb1fc8fea810c6d4e6feb42c24fb57e8066de
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR180 LRRK2 PDS5A ZFHX3	2.16e-04	168	78	4	d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Microglia/Mac\|Myeloid_cells / Location, Cell class and cell subclass	KNTC1 COL24A1 ARHGEF12 NEB	2.21e-04	169	78	4	dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIAA0825 CROCC2 RP1 DNAH9	2.21e-04	169	78	4	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP ANK2 XIRP2 RYR2	2.26e-04	170	78	4	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	ARHGEF12 ADGRF5 RP1 PHLDB2	2.26e-04	170	78	4	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	368C-Lymphocytic-ILC\|368C / Donor, Lineage, Cell class and subclass (all cells)	MDN1 IKZF1 MINDY2 CCDC7	2.31e-04	171	78	4	3b3143e4aa6520ee9c6b6f2482206ad3d8205d14
ToppCell	368C-Lymphocytic-ILC-ILC-2\|368C / Donor, Lineage, Cell class and subclass (all cells)	MDN1 IKZF1 MINDY2 CCDC7	2.31e-04	171	78	4	fd01076574dcc82bfd4a1538812500543b16794f
ToppCell	wk_20-22-Mesenchymal-Chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SOX5 COL24A1 ZFHX3 SCARA3	2.31e-04	171	78	4	d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2-Excitatory_Neuron.Slc17a7.Neurod2-Rorb_(Nucleus_of_the_lateral_olfactory_tract_(LOT))-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	QRICH2 ZNF541 CCDC7	2.32e-04	68	78	3	6945089858778301a05ecc5895310d768768758c
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2-Excitatory_Neuron.Slc17a7.Neurod2-Rorb_(Nucleus_of_the_lateral_olfactory_tract_(LOT))\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	QRICH2 ZNF541 CCDC7	2.32e-04	68	78	3	ac9d0f473c878b96a422bbdd7088eb8125574dde
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SOX5 RAD51AP2 COL24A1 SCARA3	2.41e-04	173	78	4	1f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL24A1 ANK2 PABIR2 RYR2	2.41e-04	173	78	4	3059325901b1e5e12a1a91183f14267288b2f600
ToppCell	COVID-19-Heart-Neuronal\|Heart / Disease (COVID-19 only), tissue and cell type	FOXD3 ARHGAP24 ANK2 RPGR	2.41e-04	173	78	4	6fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL24A1 ANK2 PABIR2 RYR2	2.41e-04	173	78	4	36c8338463ee4cc432f568728d55989360f9a68d
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLA1 SCARA3 STAC RYR2	2.47e-04	174	78	4	9f2e253694eb5860c00528fda31c305c6de8a2a1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 CELF2 CRACDL ADGRF5	2.47e-04	174	78	4	3d4c05ea5719ca65e85d1f15198453034791087c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 ZFHX3 SCARA3 RYR2	2.52e-04	175	78	4	316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 ZFHX3 SCARA3 RYR2	2.52e-04	175	78	4	a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP2 PARG GOLGA3 RYR2	2.58e-04	176	78	4	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	Severe-CD4+_T_activated\|Severe / Disease group and Cell class	SAMD9 DDX60L DNAH9 RYR2	2.63e-04	177	78	4	a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP24 POLA1 PARG DMXL1	2.63e-04	177	78	4	95760841b3f085d38c4926b258a33563d93a2016
ToppCell	Severe-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SOX5 SAMD9 LRRK2 NEB	2.69e-04	178	78	4	b7374a97c51239782bed658381a02cb1b3d9bf66
ToppCell	390C-Endothelial_cells-Endothelial-E-\|390C / Donor, Lineage, Cell class and subclass (all cells)	TSPAN12 CRACDL ADGRF5 UNC79	2.69e-04	178	78	4	804ac3725c1f88e2212172bfb9aa01d97a735621
ToppCell	Severe-CD4+_T_activated\|World / Disease group and Cell class	SAMD9 DDX60L DNAH9 RYR2	2.69e-04	178	78	4	ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCell	390C-Endothelial_cells-Endothelial-E\|390C / Donor, Lineage, Cell class and subclass (all cells)	TSPAN12 CRACDL ADGRF5 UNC79	2.69e-04	178	78	4	ad6dc4a375664c919bd48c35c48a561fc5a7de8c
ToppCell	BAL-Mild-cDC_4\|Mild / Compartment, Disease Groups and Clusters	LRRK2 BAZ1B RPGR CCDC144A	2.75e-04	179	78	4	68511e87b12b8253de7771e5ccfc5869248b8450
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP ANK2 XIRP2 RYR2	2.87e-04	181	78	4	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	NRAP XIRP2 DDX60L RYR2	2.93e-04	182	78	4	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL24A1 ZFHX3 SCARA3 PHLDB2	2.93e-04	182	78	4	72e65a23cd36085bc880087d3cae92395de918a1
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL24A1 ARHGAP24 SCARA3 RYR2	2.93e-04	182	78	4	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	wk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SOX5 COL24A1 POLA1 SCARA3	2.93e-04	182	78	4	03a5a02acd48f0eb210485348bfe0cd21f486215
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL24A1 ZFHX3 SCARA3 PHLDB2	2.93e-04	182	78	4	05c167158815bf25d509df59ab386e1990712765
ToppCell	COVID-19-Heart-CM_4\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP ANK2 XIRP2 RYR2	2.99e-04	183	78	4	2902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCell	Mild/Remission-B_intermediate-10\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SOX5 ANK2 LRRK2 NEB	2.99e-04	183	78	4	278064c9f0582463b83bf156d34e77f60187613b
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SOX5 ARHGAP24 ANK2 NEB	2.99e-04	183	78	4	01664fce6b70a02c9d39d747b6a6aabc86d57bc2
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL24A1 CELF2 IKZF1 STAC	3.05e-04	184	78	4	2f9c5887635185dc1c6ec4e959b6d8a28b0bd020
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	NRAP ANK2 XIRP2 RYR2	3.05e-04	184	78	4	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP ANK2 XIRP2 RYR2	3.05e-04	184	78	4	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP ANK2 XIRP2 RYR2	3.11e-04	185	78	4	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SOX5 LRRK2 ADGRF5 RP1	3.18e-04	186	78	4	2ea5ff14861e5f91d0e6a5767c403a24045d715c
Drug	Thioguanosine [85-31-4]; Down 200; 12.6uM; HL60; HT_HG-U133A	EVI5 EPS15 SAMD9 IKZF1 EFCAB14 ZZEF1 DMXL1	4.64e-06	194	78	7	1264_DN
Drug	Nicergoline; Down 200; 8.2uM; PC3; HT_HG-U133A	EVI5 MTOR ZFHX3 EFCAB14 MINDY2 RYR2 DYRK2	5.13e-06	197	78	7	5775_DN
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	SOX5 NRAP CELF2 ZFHX3 FAM186B BIRC6 UNC79 GOLGA3 RYR2	2.15e-04	801	76	9	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	IgG bisecting N-acetyl glucosamine measurement	IKZF1 KIF3C	2.33e-04	9	76	2	EFO_0008426
Disease	cognitive function measurement	KNTC1 NEK3 SAMD9 CELF2 PDS5A KIF3C RAB2A PLXNB2 FAM186B BIRC6 STAC NR1D2	2.87e-04	1434	76	12	EFO_0008354
Disease	VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder)	ANK2 RYR2	2.91e-04	10	76	2	C1631597
Disease	Cognitive impairment	RYR2 DMXL1	3.55e-04	11	76	2	HP_0100543
Disease	hemorrhoid	SOX5 KIAA0825 BIRC6 PHLDB2	5.74e-04	147	76	4	EFO_0009552
Disease	Paroxysmal atrial fibrillation	SOX5 ZFHX3 KIF3C PHLDB2	7.17e-04	156	76	4	C0235480
Disease	familial atrial fibrillation	SOX5 ZFHX3 KIF3C PHLDB2	7.17e-04	156	76	4	C3468561
Disease	Persistent atrial fibrillation	SOX5 ZFHX3 KIF3C PHLDB2	7.17e-04	156	76	4	C2585653
Disease	smoking status measurement	SAMD9 NRAP CELF2 CRACDL RAB2B ZFHX3 BIRC6 UNC79 GOLGA3 RYR2	7.68e-04	1160	76	10	EFO_0006527
Disease	Atrial Fibrillation	SOX5 ZFHX3 KIF3C PHLDB2	7.89e-04	160	76	4	C0004238
Disease	body surface area	SOX5 KNTC1 COL24A1 MTOR ARHGEF12 ZFHX3 UNC79	1.35e-03	643	76	7	EFO_0022196
Disease	testosterone measurement	GPR180 SOX5 EVI5 ANK2 CYP7A1 BAZ1B ZFHX3 BIRC6 HERC4 NR1D2	1.56e-03	1275	76	10	EFO_0004908
Disease	mean corpuscular hemoglobin concentration	SOX5 KNTC1 SAMD9 TMCC2 ADGRF5 IKZF1 KIF3C NEB DMXL1	2.11e-03	1105	76	9	EFO_0004528

Protein segments in the cluster

Peptide	Gene	Start	Entry
QNAIKAMHQSQTMEG	CELF2	186	O95319
RHSMQIEQMKQLSDF	ANKRD34C	516	P0C6C1
FSQMNNIMSKSLHDD	BIRC6	646	Q9NR09
NSMFVHQDSVSKLQM	CCDC7	861	Q96M83
NQHLDSQKMDMSNIV	AKAP4	616	Q5JQC9
AQTAIKAMHQAQTME	CELF1	161	Q92879
SVQDHMETRQQMSAE	BAZ1B	761	Q9UIG0
FDLQMTKNMNQNSDS	CCDC144CP	396	Q8IYA2
EQMLQDQHTMNTKAS	FAM186B	196	Q8IYM0
MKSMEHDSSQLNELQ	CCDC172	151	P0C7W6
NVMMISKHADGSLNQ	DMXL1	596	Q9Y485
KTMELLQSDMNQHFL	EFCAB14	221	O75071
QDSQASNILVMDHMI	ARHGEF12	1346	Q9NZN5
VNMHSQDLNMERKQG	RAD51AP2	756	Q09MP3
LEDARQHSNSNMVIM	RAB2A	101	P61019
QHSNSNMVIMLIGNK	RAB2A	106	P61019
EVLMTKNENNSHAFM	PDS5A	1036	Q29RF7
QHSSSNMVIMLIGNK	RAB2B	106	Q8WUD1
QFDATTEQLNHMMQE	QRICH2	1336	Q9H0J4
LLQNDHNADVQSKMM	ANK2	211	Q01484
HNADVQSKMMVNRTT	ANK2	216	Q01484
DQKLLEMENIMHSQN	RB1CC1	931	Q8TDY2
MNINMNKHLVTGSVQ	VCPKMT	106	Q9H867
NHAQQQMKMTENTLL	MDN1	801	Q9NU22
KSIMGDQTSIHNQMI	KIAA0825	1056	Q8IV33
GDSQMSHSLQMSKLQ	NRAP	841	Q86VF7
MATQSDMEKEQKHQQ	EZHIP	1	Q86X51
EKLQEMQIQMSQNHL	DDX60L	1691	Q5H9U9
RNIMDHTNEQQKMLE	KIF3C	526	O14782
QMVQVSDQDMNTHLA	PLXNB2	1761	O15031
KQKMNHSITMSQEQI	PARG	616	Q86W56
RMMEMETQNQINSNH	EVI5	586	O60447
TDAVLQMQMAIDQAH	HERC4	676	Q5GLZ8
FHQMSSNIMEQKDQQ	LRRK2	676	Q5S007
KMHAMNTNNITELVN	KNTC1	2151	P50748
SKAQLTMTMNQTEHN	GPR180	96	Q86V85
TMTMNQTEHNLTVSQ	GPR180	101	Q86V85
MKSHVMDQAINNAIN	IKZF1	306	Q13422
MLSKDNTVHDLRQQM	GOLGA3	526	Q08378
LSHQNLAQSAVMMEK	CRACDL	911	Q6NV74
TMQNAKNHQNEIIAM	POLA1	546	P09884
VQHESSNQMFAMKEI	NEK3	21	P51956
FLQNETNETIHMQMS	MAS1L	51	P35410
AHEREMQTAMQISQS	PABIR2	71	Q7Z309
HQQFSMMNLDDKQSI	ARHGAP24	536	Q8N264
TRTMQIDNFMSHDKQ	CCDC82	446	Q8N4S0
ELTNQMNQIEISMQH	HAT1	381	O14929
QAQMTEMEQAHTQRL	CROCC2	1561	H7BZ55
FDLQMTKNMNQNSDS	CCDC144B	446	Q3MJ40
MNQVQSAMDESHILE	BPIFB6	31	Q8NFQ5
HALNSLTESMMENLQ	CYP7A1	136	P22680
HLQDSQQEISSMQMK	EPS15	481	P42566
KGELTMTSHMENLQN	DNAH9	4281	Q9NYC9
FDLQMTKNMNQNSDS	CCDC144A	446	A2RUR9
SQNSESMHDLVLQVM	SCARA3	291	Q6AZY7
FAHMQMKLSQDSSQI	RYR2	3951	Q92736
QDKDNTMNVIHMLEN	DYRK2	276	Q92630
QQEHLREQTALMMQS	FOXD3	241	Q9UJU5
DHKPASNMQTETVMQ	KIF23	821	Q02241
EITSQKMLEMSHNNG	RP1	551	P56715
KNMCEHSNTLVQQAM	MTOR	1996	P42345
HSNTLVQQAMMVSEE	MTOR	2001	P42345
KTMMNSQFSGHLQND	NR1D2	196	Q14995
NMTHIMSLNSNEKSL	RPGR	501	Q92834
QNMSDAMAILHKLQT	MINDY2	321	Q8NBR6
HQNEMTNLKQELASM	TMCC2	576	O75069
HLNKSQIMLDMLTEN	SAMD9	1001	Q5K651
DKQNDFMQSILHTME	SETX	261	Q7Z333
DSVVHSVENDSQNMM	PHLDB2	21	Q86SQ0
QVNSEMMTHVLSTVN	ADGRF5	786	Q8IZF2
AITANLHTNELMEMQ	COL24A1	411	Q17RW2
TMQQAQKHTEMITTL	PSIP1	386	O75475
MNKMHQSQEESAVTI	XIRP2	491	A4UGR9
EEMMTLTEQHLESQN	SAMD4B	326	Q5PRF9
FQRTNSEDMKLQAHM	STAC	61	Q99469
GTDQMMSLKNDNSQH	TSPAN12	256	O95859
MMNVTEQEHKQSLQL	ZZEF1	881	O43149
QHNTMEVDGNKVMSS	SOX5	86	P35711
SQNISDENQTHEMIM	ZNF713	116	Q8N859
SHEQMQVFQMITKSQ	ZNF541	551	Q9H0D2
LSIHMQSDKHLNNMQ	ZFHX3	741	Q15911
MSQLMKRQLEHQSSA	UNC79	1921	Q9P2D8
MKESLIMNHVLNTSQ	NEB	5846	P20929