Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglycine binding

GLRA1 GLRB GLRA3 GRIN3B

4.64e-0714954GO:0016594
GeneOntologyMolecularFunctionextracellularly glycine-gated ion channel activity

GLRA1 GLRB GLRA3

2.06e-066953GO:0016933
GeneOntologyMolecularFunctionextracellularly glycine-gated chloride channel activity

GLRA1 GLRB GLRA3

2.06e-066953GO:0016934
GeneOntologyMolecularFunctioninhibitory extracellular ligand-gated monoatomic ion channel activity

GLRA1 GLRB GLRA3

5.74e-068953GO:0005237
GeneOntologyMolecularFunctiontype I interferon receptor binding

IFNA7 IFNA14 IFNA16

6.76e-0517953GO:0005132
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

GLRA1 GLRB GLRA3 ANO3

9.36e-0550954GO:0099095
GeneOntologyMolecularFunctionDNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

TOP6BL TOP2A

1.34e-044952GO:0003918
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC12A3 GLRA1 GLRB GLRA3 ABCC11 ANO3

1.67e-04171956GO:0015103
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GLRA1 GLRB GLRA3 GRIN3B

2.61e-0465954GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GLRA1 GLRB GLRA3 GRIN3B

2.61e-0465954GO:0022824
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC12A3 GLRA1 GLRB GLRA3 ANO3

3.28e-04125955GO:0015108
GeneOntologyMolecularFunctionhistone H3K27 methyltransferase activity

EHMT1 NSD3

3.32e-046952GO:0046976
GeneOntologyMolecularFunctionlipid transporter activity

SLCO1B7 PITPNM2 SLCO1A2 ABCC11 PITPNC1 ANO3

3.49e-04196956GO:0005319
GeneOntologyMolecularFunctionamino acid binding

GLRA1 GLRB GLRA3 GRIN3B

4.07e-0473954GO:0016597
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GLRA1 GLRB GLRA3 GRIN3B

4.99e-0477954GO:0005230
GeneOntologyMolecularFunctionbile acid transmembrane transporter activity

SLCO1B7 SLCO1A2 ABCC11

5.61e-0434953GO:0015125
GeneOntologyMolecularFunctionDNA topoisomerase activity

TOP6BL TOP2A

6.16e-048952GO:0003916
GeneOntologyMolecularFunctionchloride channel activity

GLRA1 GLRB GLRA3 ANO3

7.58e-0486954GO:0005254
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC12A3 GLRA1 GLRB GLRA3 ANO3

7.76e-04151955GO:0008509
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor

BCKDHB OGDH

7.89e-049952GO:0016624
GeneOntologyMolecularFunctionexcitatory extracellular ligand-gated monoatomic ion channel activity

GLRA1 GLRB GLRA3

1.12e-0343953GO:0005231
GeneOntologyMolecularFunctionphosphatidylinositol transfer activity

PITPNM2 PITPNC1

1.20e-0311952GO:0008526
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

EHMT1 METTL23 NSD3

1.20e-0344953GO:0140938
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GLRA1 GLRB GLRA3 GRIN3B

1.33e-03100954GO:0030594
GeneOntologyMolecularFunctionmonoatomic anion channel activity

GLRA1 GLRB GLRA3 ANO3

1.48e-03103954GO:0005253
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GLRA1 GLRB GLRA3 GRIN3B ANO3

2.30e-03193955GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

GLRA1 GLRB GLRA3 GRIN3B ANO3

2.51e-03197955GO:0022834
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GLRA1 GLRB GRIN3B

2.53e-0357953GO:1904315
GeneOntologyMolecularFunctionribosome binding

NOMO2 OLA1 NOMO3 NOMO1

2.59e-03120954GO:0043022
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GLRA1 GLRB GRIN3B

2.93e-0360953GO:0099529
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLCO1B7 SLCO1A2

3.26e-0318952GO:0015347
GeneOntologyMolecularFunctionSUMO ligase activity

PIAS2 PIAS1

4.02e-0320952GO:0061665
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

PITPNM2 PITPNC1

4.02e-0320952GO:0008525
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

EHMT1 METTL23 NSD3

4.18e-0368953GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

EHMT1 METTL23 NSD3

4.36e-0369953GO:0016278
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

SLCO1B7 SLCO1A2 ABCC11

4.54e-0370953GO:1901618
GeneOntologyMolecularFunctionhistone methyltransferase activity

EHMT1 METTL23 NSD3

4.72e-0371953GO:0042054
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

SLCO1B7 SLCO1A2 ABCC11

5.10e-0373953GO:0170055
GeneOntologyMolecularFunctionphospholipid transporter activity

PITPNM2 PITPNC1 ANO3

5.30e-0374953GO:0005548
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GLRA1 GLRB GRIN3B

5.50e-0375953GO:0098960
GeneOntologyBiologicalProcessmulti-pass transmembrane protein insertion into ER membrane

NOMO2 NOMO3 NOMO1

7.55e-069943GO:0160063
GeneOntologyBiologicalProcessmonoatomic anion transport

SLC12A3 SLCO1A2 GLRA1 GLRB GLRA3 ABCC11 ANO3

2.06e-05183947GO:0006820
GeneOntologyBiologicalProcesspeptidyl-amino acid modification

DIP2B PPP2R5B ATR PDGFRA TTLL2 TRPC6 LRRK2 EHMT1 GCSH METTL23 PIAS2 PIAS1 IFNA7 IFNA14 IFNA16

3.35e-059769415GO:0018193
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

SLC12A3 GLRA1 GLRB GLRA3 ABCC11 ANO3

7.18e-05153946GO:0098656
GeneOntologyBiologicalProcessprotein insertion into membrane

NOMO2 GRIN3B NOMO3 NOMO1

7.93e-0550944GO:0051205
GeneOntologyBiologicalProcesspeptidyl-lysine modification

DIP2B EHMT1 GCSH METTL23 PIAS2 PIAS1

9.85e-05162946GO:0018205
GeneOntologyBiologicalProcesspositive regulation of peptidyl-serine phosphorylation of STAT protein

IFNA7 IFNA14 IFNA16

1.15e-0421943GO:0033141
GeneOntologyBiologicalProcessendoplasmic reticulum organization

NOMO2 LPCAT3 LRRK2 NOMO3 NOMO1

1.30e-04107945GO:0007029
GeneOntologyBiologicalProcesschloride transmembrane transport

SLC12A3 GLRA1 GLRB GLRA3 ANO3

1.61e-04112945GO:1902476
GeneOntologyBiologicalProcessregulation of peptidyl-serine phosphorylation of STAT protein

IFNA7 IFNA14 IFNA16

1.73e-0424943GO:0033139
GeneOntologyBiologicalProcesschylomicron assembly

CES1 LPCAT3

2.04e-045942GO:0034378
GeneOntologyBiologicalProcesssynaptic transmission, glycinergic

GLRA1 GLRB

2.04e-045942GO:0060012
GeneOntologyBiologicalProcessserine phosphorylation of STAT protein

IFNA7 IFNA14 IFNA16

2.76e-0428943GO:0042501
GeneOntologyBiologicalProcesschloride transport

SLC12A3 GLRA1 GLRB GLRA3 ANO3

3.00e-04128945GO:0006821
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

SLC12A3 GLRA1 GLRB GLRA3 ANO3

3.71e-04134945GO:0098661
GeneOntologyBiologicalProcessprotein insertion into ER membrane

NOMO2 NOMO3 NOMO1

3.76e-0431943GO:0045048
GeneOntologyCellularComponentmulti-pass translocon complex

NOMO2 NOMO3 NOMO1

7.49e-069953GO:0160064
GeneOntologyCellularComponentglycine-gated chloride channel complex

GLRB GLRA3

2.04e-052952GO:0016935
GeneOntologyCellularComponentER membrane insertion complex

NOMO2 NOMO3 NOMO1

3.19e-0514953GO:0072379
GeneOntologyCellularComponentglycinergic synapse

GLRA1 GLRB GLRA3

9.80e-0520953GO:0098690
DomainDUF2012

NOMO2 NOMO3 NOMO1

4.76e-074933PF09430
DomainDUF2012

NOMO2 NOMO3 NOMO1

4.76e-074933IPR019008
DomainCarb-bd-like_fold

NOMO2 NOMO3 NOMO1

6.57e-068933IPR013784
DomainCarboxyPept_regulatory_dom

NOMO2 NOMO3 NOMO1

3.30e-0513933IPR014766
Domain-

NOMO2 NOMO3 NOMO1

3.30e-05139332.60.40.1120
DomainBand_7/stomatin-like_CS

STOML3 STOM

7.33e-053932IPR018080
DomainBAND_7

STOML3 STOM

7.33e-053932PS01270
DomainInterferon_alpha/beta/delta

IFNA7 IFNA14 IFNA16

7.73e-0517933IPR000471
DomainCarboxyPept-like_regulatory

NOMO2 NOMO3 NOMO1

7.73e-0517933IPR008969
DomainInterferon

IFNA7 IFNA14 IFNA16

7.73e-0517933PF00143
DomainIFabd

IFNA7 IFNA14 IFNA16

7.73e-0517933SM00076
DomainINTERFERON_A_B_D

IFNA7 IFNA14 IFNA16

7.73e-0517933PS00252
DomainPINIT

PIAS2 PIAS1

1.46e-044932IPR023321
DomainGlycine_rcpt_A

GLRA1 GLRA3

1.46e-044932IPR008127
DomainPINIT

PIAS2 PIAS1

1.46e-044932PS51466
DomainPINIT

PIAS2 PIAS1

1.46e-044932PF14324
DomainStomatin_fam

STOML3 STOM

2.43e-045932IPR001972
DomainIP_trans

PITPNM2 PITPNC1

2.43e-045932PF02121
DomainPI_transfer

PITPNM2 PITPNC1

3.63e-046932IPR001666
DomainDDHD

PITPNM2 SEC23IP

3.63e-046932PF02862
DomainDDHD

PITPNM2 SEC23IP

3.63e-046932PS51043
DomainDDHD_dom

PITPNM2 SEC23IP

3.63e-046932IPR004177
DomainDDHD

PITPNM2 SEC23IP

3.63e-046932SM01127
DomainTGS-like

MRPL39 OLA1

5.07e-047932IPR012676
Domainzf-MIZ

PIAS2 PIAS1

5.07e-047932PF02891
DomainZF_SP_RING

PIAS2 PIAS1

5.07e-047932PS51044
DomainMan6P_isomerase_rcpt-bd_dom

ELAPOR2 ELAPOR1

6.74e-048932IPR009011
DomainTransket_pyr

BCKDHB OGDH

6.74e-048932SM00861
DomainTransket_pyr

BCKDHB OGDH

6.74e-048932PF02779
DomainZnf_MIZ

PIAS2 PIAS1

6.74e-048932IPR004181
DomainTransketolase-like_Pyr-bd

BCKDHB OGDH

6.74e-048932IPR005475
DomainHAT

UTP6 ZFC3H1

1.08e-0310932IPR003107
DomainHAT

UTP6 ZFC3H1

1.08e-0310932SM00386
DomainBand_7

STOML3 STOM

1.31e-0311932IPR001107
DomainBand_7

STOML3 STOM

1.31e-0311932PF01145
DomainPHB

STOML3 STOM

1.31e-0311932SM00244
DomainNeurotransmitter_ion_chnl_CS

GLRA1 GLRB GLRA3

1.46e-0345933IPR018000
DomainARM-type_fold

IFRD1 PPP2R5B ATR NBEAL1 LRRK2 ARFGEF2 NCAPG2

1.52e-03339937IPR016024
DomainNeur_chan_memb

GLRA1 GLRB GLRA3

1.55e-0346933PF02932
DomainOA_transporter

SLCO1B7 SLCO1A2

1.57e-0312932IPR004156
DomainOATP

SLCO1B7 SLCO1A2

1.57e-0312932PF03137
DomainNeur_chan_LBD

GLRA1 GLRB GLRA3

1.65e-0347933PF02931
DomainNEUROTR_ION_CHANNEL

GLRA1 GLRB GLRA3

1.65e-0347933PS00236
DomainNeurotrans-gated_channel_TM

GLRA1 GLRB GLRA3

1.65e-0347933IPR006029
Domain-

GLRA1 GLRB GLRA3

1.65e-03479332.70.170.10
DomainNeur_channel

GLRA1 GLRB GLRA3

1.65e-0347933IPR006201
DomainNeur_chan_lig-bd

GLRA1 GLRB GLRA3

1.65e-0347933IPR006202
Domain-

ADAMTSL1 PDGFRA MYCBP2 NOMO2 ADAMTSL3 IL1RAP IL22RA1 F13A1 NOMO3 NOMO1

1.69e-0366393102.60.40.10
DomainTHDP-binding

BCKDHB OGDH

1.85e-0313932IPR029061
Domain-

BCKDHB OGDH

1.85e-03139323.40.50.970
Domain-

IFNA7 IFNA14 IFNA16

1.98e-03509331.20.1250.10
Domain4_helix_cytokine_core

IFNA7 IFNA14 IFNA16

2.09e-0351933IPR012351
DomainKazal_dom

SLCO1B7 ACRBP SLCO1A2

2.09e-0351933IPR002350
DomainBeta-grasp_dom

MRPL39 OLA1

2.15e-0314932IPR012675
DomainPLAC

ADAMTSL1 ADAMTSL3

2.15e-0314932PF08686
Domain-

MRPL39 OLA1

2.15e-03149323.10.20.30
DomainIg-like_fold

ADAMTSL1 PDGFRA MYCBP2 NOMO2 ADAMTSL3 IL1RAP IL22RA1 F13A1 NOMO3 NOMO1

2.68e-037069310IPR013783
DomainPLAC

ADAMTSL1 ADAMTSL3

3.97e-0319932PS50900
DomainPLAC

ADAMTSL1 ADAMTSL3

3.97e-0319932IPR010909
Domain-

PIAS2 PIAS1

4.84e-03219321.10.720.30
PathwayBIOCARTA_IL1R_PATHWAY

IL1RAP IFNA7 IFNA14 IFNA16

5.80e-0541734MM1493
PathwayKEGG_MEDICUS_PATHOGEN_HIV_TAT_TO_TLR2_4_NFKB_SIGNALING_PATHWAY

IFNA7 IFNA14 IFNA16

8.60e-0517733M47564
PathwayKEGG_MEDICUS_REFERENCE_CGAS_STING_SIGNALING_PATHWAY

IFNA7 IFNA14 IFNA16

1.03e-0418733M47539
PathwayBIOCARTA_IFNA_PATHWAY

IFNA7 IFNA14 IFNA16

1.22e-0419733MM1571
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF7_SIGNALING_PATHWAY

IFNA7 IFNA14 IFNA16

1.22e-0419733M47450
PathwayKEGG_MEDICUS_REFERENCE_CONDENSIN_LOADING

PPP2R5B NCAPG2 TOP2A

1.43e-0420733M47876
PathwayKEGG_MEDICUS_REFERENCE_TLR7_9_IRF7_SIGNALING_PATHWAY

IFNA7 IFNA14 IFNA16

1.43e-0420733M47617
PathwayKEGG_JAK_STAT_SIGNALING_PATHWAY

PIAS2 IL22RA1 PIAS1 IFNA7 IFNA14 IFNA16

1.49e-04155736M17411
PathwayKEGG_MEDICUS_REFERENCE_TYPE_II_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY

IFNA7 IFNA14 IFNA16

1.66e-0421733M47909
PathwayKEGG_MEDICUS_REFERENCE_TLR7_8_9_IRF5_SIGNALING_PATHWAY

IFNA7 IFNA14 IFNA16

1.91e-0422733M47897
PathwayKEGG_MEDICUS_REFERENCE_RIG_I_NFKB_SIGNALING_PATHWAY

IFNA7 IFNA14 IFNA16

1.91e-0422733M47616
PathwayKEGG_MEDICUS_REFERENCE_TYPE_I_IFN_SIGNALING_PATHWAY

IFNA7 IFNA14 IFNA16

2.19e-0423733M47452
PathwayREACTOME_REGULATION_OF_IFNA_IFNB_SIGNALING

IFNA7 IFNA14 IFNA16

2.19e-0423733MM15634
PathwayKEGG_MEDICUS_REFERENCE_RIG_I_IRF7_3_SIGNALING_PATHWAY

IFNA7 IFNA14 IFNA16

2.49e-0424733M47576
PathwayKEGG_MEDICUS_REFERENCE_MDA5_IRF7_3_SIGNALING_PATHWAY

IFNA7 IFNA14 IFNA16

2.49e-0424733M47782
PathwayKEGG_MEDICUS_REFERENCE_TYPE_I_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY

IFNA7 IFNA14 IFNA16

2.49e-0424733M47908
PathwayREACTOME_REGULATION_OF_IFNA_IFNB_SIGNALING

IFNA7 IFNA14 IFNA16

3.18e-0426733M982
PathwayBIOCARTA_CYTOKINE_PATHWAY

IFNA7 IFNA14 IFNA16

3.98e-0428733MM1378
PathwayKEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION

PDGFRA TNFRSF19 IL1RAP IL22RA1 IFNA7 IFNA14 IFNA16

4.24e-04264737M9809
PathwayREACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION

IFNA7 IFNA14 IFNA16

4.89e-0430733M936
PathwayWP_SARS_CORONAVIRUS_AND_INNATE_IMMUNITY

IFNA7 IFNA14 IFNA16

5.40e-0431733M39897
PathwayKEGG_MEDICUS_REFERENCE_IFN_RIPK1_3_SIGNALING_PATHWAY

IFNA7 IFNA14 IFNA16

5.40e-0431733M47964
PathwayREACTOME_GLYCINE_DEGRADATION

GCSH OGDH

5.46e-047732M48229
PathwayREACTOME_GLYCINE_DEGRADATION

GCSH OGDH

5.46e-047732MM17221
PathwayBIOCARTA_INFLAM_PATHWAY

IFNA7 IFNA14 IFNA16

6.50e-0433733MM1379
PathwayREACTOME_INTERFERON_ALPHA_BETA_SIGNALING

IFNA7 IFNA14 IFNA16

7.10e-0434733MM15631
PathwayREACTOME_EVASION_BY_RSV_OF_HOST_INTERFERON_RESPONSES

IFNA7 IFNA14 IFNA16

7.74e-0435733M48246
PathwayKEGG_REGULATION_OF_AUTOPHAGY

IFNA7 IFNA14 IFNA16

7.74e-0435733M6382
PathwayWP_INTERFERONMEDIATED_SIGNALING

IFNA7 IFNA14 IFNA16

9.12e-0437733M39785
PathwayWP_CYTOKINES_AND_INFLAMMATORY_RESPONSE

IFNA7 IFNA14 IFNA16

1.07e-0339733MM15914
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RAE1 PIAS2 PIAS1

1.07e-0339733M27238
PathwayBIOCARTA_RANBP2_PATHWAY

PIAS2 PIAS1

1.41e-0311732M22027
PathwayPID_RANBP2_PATHWAY

PIAS2 PIAS1

1.41e-0311732M140
PathwayKEGG_LYSINE_DEGRADATION

EHMT1 OGDH NSD3

1.52e-0344733M13720
PathwayREACTOME_TRANSPORT_OF_ORGANIC_ANIONS

SLCO1B7 SLCO1A2

1.69e-0312732MM15476
PathwayREACTOME_STIMULI_SENSING_CHANNELS

TRPC6 STOML3 ANO3 STOM

1.72e-0399734MM14910
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RAE1 PIAS2 PIAS1

1.83e-0347733MM14939
PathwayREACTOME_STIMULI_SENSING_CHANNELS

TRPC6 STOML3 ANO3 STOM

2.21e-03106734M27200
Pubmed

Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.

NOMO2 NOMO3 NOMO1

1.97e-08395336011023
Pubmed

Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.

NOMO2 NOMO3 NOMO1

1.97e-08395325576386
Pubmed

Expression and mRNA splicing of glycine receptor subunits and gephyrin during neuronal differentiation of P19 cells in vitro, studied by RT-PCR and immunocytochemistry.

GLRA1 GLRB GLRA3

7.88e-0849539051263
Pubmed

Activation of glycine receptor phase-shifts the circadian rhythm in neuronal activity in the mouse suprachiasmatic nucleus.

GLRA1 GLRB GLRA3

7.88e-08495321486797
Pubmed

Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.

NOMO2 NOMO3 NOMO1

7.88e-08495331833031
Pubmed

Alpha subunit-dependent glycine receptor clustering and regulation of synaptic receptor numbers.

GLRA1 GLRB GLRA3

7.88e-08495328883437
Pubmed

A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.

NOMO2 NOMO3 NOMO1

7.88e-0849539267806
Pubmed

Rearrangement of genes located on homologous chromosomal segments in mouse and man: the location of genes for alpha- and beta-interferon, alpha-1 acid glycoprotein-1 and -2, and aminolevulinate dehydratase on mouse chromosome 4.

ORM2 IFNA7 IFNA14 IFNA16

9.27e-08169543100390
Pubmed

Developmental regulation of glycine receptors at efferent synapses of the murine cochlea.

GLRA1 GLRB GLRA3

1.97e-07595321850450
Pubmed

OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.

SLCO1B7 CES1 SLCO1A2

1.97e-07595324194565
Pubmed

Native glycine receptor subtypes and their physiological roles.

GLRA1 GLRB GLRA3

1.97e-07595318721822
Pubmed

Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.

NOMO2 NOMO3 NOMO1

1.09e-06895315257293
Pubmed

Substrate-driven assembly of a translocon for multipass membrane proteins.

NOMO2 NOMO3 NOMO1

1.64e-06995336261522
Pubmed

Effect of interferon-alpha on immediate early gene expression of murine cytomegalovirus.

IFNA7 IFNA14 IFNA16

3.21e-06119538389790
Pubmed

Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis.

IFNA7 IFNA14 IFNA16

3.21e-061195318835032
Pubmed

High-affinity binding of 125I-labelled mouse interferon to a specific cell surface receptor.

IFNA7 IFNA14 IFNA16

3.21e-06119536444699
Pubmed

The mouse IFN-alpha (Ifa) locus: correlation of physical and linkage maps by in situ hybridization.

IFNA7 IFNA14 IFNA16

3.21e-06119533456887
Pubmed

Mechanism of SUMOylation-Mediated Regulation of Type I IFN Expression.

IFNA7 IFNA14 IFNA16

3.21e-061195336681180
Pubmed

Type I interferon dependence of plasmacytoid dendritic cell activation and migration.

IFNA7 IFNA14 IFNA16

3.21e-061195315795237
Pubmed

Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration.

IFNA7 IFNA14 IFNA16

3.21e-06119539794439
Pubmed

An ER translocon for multi-pass membrane protein biogenesis.

NOMO2 NOMO3 NOMO1

3.21e-061195332820719
Pubmed

Structural and functional neuropathology in transgenic mice with CNS expression of IFN-alpha.

IFNA7 IFNA14 IFNA16

3.21e-061195310448195
Pubmed

Recombinant rabies virus expressing IFNα1 enhanced immune responses resulting in its attenuation and stronger immunogenicity.

IFNA7 IFNA14 IFNA16

3.21e-061195325310498
Pubmed

IFN-alpha can both protect against and promote the development of type 1 diabetes.

IFNA7 IFNA14 IFNA16

3.21e-061195319120292
Pubmed

Type I interferon production by tertiary lymphoid tissue developing in response to 2,6,10,14-tetramethyl-pentadecane (pristane).

IFNA7 IFNA14 IFNA16

4.27e-061295316565497
Pubmed

AAV2-mediated combined subretinal delivery of IFN-α and IL-4 reduces the severity of experimental autoimmune uveoretinitis.

IFNA7 IFNA14 IFNA16

4.27e-061295322685550
Pubmed

Sequence and expression of a novel murine interferon alpha gene--homology with enhancer elements in the regulatory region of the gene.

IFNA7 IFNA14 IFNA16

4.27e-06129533017340
Pubmed

Regulation of effector and memory T-cell functions by type I interferon.

IFNA7 IFNA14 IFNA16

4.27e-061295321320124
Pubmed

MAVS Deficiency Is Associated With a Reduced T Cell Response Upon Secondary RSV Infection in Mice.

IFNA7 IFNA14 IFNA16

4.27e-061295333123150
Pubmed

Interferon-alpha/beta genes are up-regulated in murine brain astrocytes after infection with Theiler's murine encephalomyelitis virus.

IFNA7 IFNA14 IFNA16

4.27e-061295320038206
Pubmed

Murine alpha/beta interferons inhibit benzo(a)pyrene activation and mutagenesis in mice.

IFNA7 IFNA14 IFNA16

4.27e-06129538304945
Pubmed

The virus-induced factor VIF differentially recognizes the virus-responsive modules of the mouse IFNA4 gene promoter.

IFNA7 IFNA14 IFNA16

4.27e-061295311846978
Pubmed

A novel anti-viral role for STAT3 in IFN-α signalling responses.

IFNA7 IFNA14 IFNA16

4.27e-061295327988795
Pubmed

Identification of distal silencing elements in the murine interferon-A11 gene promoter.

IFNA7 IFNA14 IFNA16

4.27e-06129538760352
Pubmed

Evolution of the interferon alpha gene family in eutherian mammals.

IFNA7 IFNA14 IFNA16

4.27e-061295317512142
Pubmed

IFN-alpha-mediated suppression of low-affinity FC(epsilon) receptors on Peyer's patch lymphocytes and augmentation of soluble CD23: implications for IgE responses.

IFNA7 IFNA14 IFNA16

4.27e-06129538656058
Pubmed

Repression of the murine interferon alpha 11 gene: identification of negatively acting sequences.

IFNA7 IFNA14 IFNA16

4.27e-06129531886773
Pubmed

Behavioral effects of mouse interferons-alpha and -gamma and human interferon-alpha in mice.

IFNA7 IFNA14 IFNA16

4.27e-06129531422836
Pubmed

The physical separation of Lps and Ifa loci in BXH recombinant inbred mice.

IFNA7 IFNA14 IFNA16

4.27e-06129532572648
Pubmed

Developmental control of IFN-alpha expression in murine embryos.

IFNA7 IFNA14 IFNA16

4.27e-06129537925651
Pubmed

The role of type 1 interferons in coagulation induced by gram-negative bacteria.

IFNA7 IFNA14 IFNA16

4.27e-061295332016282
Pubmed

Role of interferons in the regulation of cell proliferation, differentiation, and development.

IFNA7 IFNA14 IFNA16

4.27e-06129537530016
Pubmed

Suppression of the effector phase of inflammatory arthritis by double-stranded RNA is mediated by type I IFNs.

IFNA7 IFNA14 IFNA16

4.27e-061295317277125
Pubmed

Nonviral interferon alpha gene therapy inhibits growth of established tumors by eliciting a systemic immune response.

IFNA7 IFNA14 IFNA16

4.27e-06129539794206
Pubmed

Multiple pathways of interferon-induced gene expression in murine macrophages.

IFNA7 IFNA14 IFNA16

4.27e-06129537684767
Pubmed

Isolation and mapping of four new DNA markers from mouse chromosome 4.

IFNA7 IFNA14 IFNA16

4.27e-06129531360280
Pubmed

Structure and expression of cloned murine IFN-alpha genes.

IFNA7 IFNA14 IFNA16

4.27e-06129536188104
Pubmed

Ligation of CD180 inhibits IFN-α signaling in a Lyn-PI3K-BTK-dependent manner in B cells.

IFNA7 IFNA14 IFNA16

4.27e-061295326277892
Pubmed

Mapping of murine interferon-alpha genes to chromosome 4.

IFNA7 IFNA14 IFNA16

4.27e-06129536689487
Pubmed

Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice.

IFNA7 IFNA14 IFNA16

4.27e-061295318716002
Pubmed

Characterization of murine interferon-alpha 12 (MuIFN-alpha12): biological activities and gene expression.

IFNA7 IFNA14 IFNA16

4.27e-061295317451966
Pubmed

Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes.

IFNA7 IFNA14 IFNA16

4.27e-061295325897172
Pubmed

Negative regulation of the alpha interferon-induced antiviral response by the Ras/Raf/MEK pathway.

IFNA7 IFNA14 IFNA16

4.27e-061295316611902
Pubmed

Obesity worsens the outcome of influenza virus infection associated with impaired type I interferon induction in mice.

IFNA7 IFNA14 IFNA16

4.27e-061295330967261
Pubmed

A polymorphic trinucleotide repeat sequence mapping to distal mouse chromosome 4.

IFNA7 IFNA14 IFNA16

4.27e-06129538672140
Pubmed

Interferon-alpha subtype 11 activates NK cells and enables control of retroviral infection.

IFNA7 IFNA14 IFNA16

4.27e-061295322912583
Pubmed

The antiviral cytokines IFN-α and IFN-β modulate parietal epithelial cells and promote podocyte loss: implications for IFN toxicity, viral glomerulonephritis, and glomerular regeneration.

IFNA7 IFNA14 IFNA16

4.27e-061295323747509
Pubmed

Antiviral and myocyte protective effects of murine interferon-beta and -{alpha}2 in coxsackievirus B3-induced myocarditis and epicarditis in Balb/c mice.

IFNA7 IFNA14 IFNA16

4.27e-061295317434974
Pubmed

Mutation of the IFNAR-1 receptor binding site of human IFN-alpha2 generates type I IFN competitive antagonists.

IFNA7 IFNA14 IFNA16

4.27e-061295318937499
Pubmed

Structure and expression of a new murine interferon-alpha gene: MuIFN-alpha I9.

IFNA7 IFNA14 IFNA16

4.27e-06129533758677
Pubmed

Interferon-alpha/beta can impede development of carcinogen-induced squamous-cell tumors in the esophagus of C57B1 mice.

IFNA7 IFNA14 IFNA16

4.27e-06129537601556
Pubmed

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling.

IFNA7 IFNA14 IFNA16

4.27e-061295319406830
Pubmed

Mapping the genetic region coding for herpes simplex virus resistance to mouse interferon alpha/beta.

IFNA7 IFNA14 IFNA16

4.27e-06129538245849
Pubmed

Characterization of interferon-alpha 13, a novel constitutive murine interferon-alpha subtype.

IFNA7 IFNA14 IFNA16

5.54e-061395312930842
Pubmed

Cutting edge: IL-12 and type I IFN differentially program CD8 T cells for programmed death 1 re-expression levels and tumor control.

IFNA7 IFNA14 IFNA16

5.54e-061395323804712
Pubmed

Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses.

IFNA7 IFNA14 IFNA16

5.54e-061395322431588
Pubmed

Mouse interferon alpha and beta genes are linked at the centromere proximal region of chromosome 4.

IFNA7 IFNA14 IFNA16

5.54e-06139533973562
Pubmed

Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release.

IFNA7 IFNA14 IFNA16

5.54e-06139532014240
Pubmed

An interferon-alpha-induced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein.

IFNA7 IFNA14 IFNA16

5.54e-061395318005734
Pubmed

Differential effect of murine alpha/beta interferon transgenes on antagonization of herpes simplex virus type 1 replication.

IFNA7 IFNA14 IFNA16

5.54e-061395312050368
Pubmed

Organization, structure and expression of murine interferon alpha genes.

IFNA7 IFNA14 IFNA16

5.54e-06139532987810
Pubmed

Isolation and bacterial expression of a murine alpha leukocyte interferon gene.

IFNA7 IFNA14 IFNA16

5.54e-06139536094686
Pubmed

Segregation of restriction fragment length polymorphism in an interspecies cross of laboratory and wild mice indicates tight linkage of the murine IFN-beta gene to the murine IFN-alpha genes.

IFNA7 IFNA14 IFNA16

5.54e-06139532993652
Pubmed

Anti-retroviral effects of type I IFN subtypes in vivo.

IFNA7 IFNA14 IFNA16

5.54e-061395319130550
Pubmed

Isolation and characterization of a novel interferon-alpha-encoding gene, IFN-alpha 11, within a murine IFN cluster.

IFNA7 IFNA14 IFNA16

5.54e-06139531655578
Pubmed

Type I IFN protects against antigen-induced arthritis.

IFNA7 IFNA14 IFNA16

5.54e-061395321469099
Pubmed

Isolation and characterization of a functional murine interferon alpha gene which is not expressed in fibroblasts upon virus induction.

IFNA7 IFNA14 IFNA16

5.54e-06139532471809
Pubmed

HIV-1 Gag-virus-like particles inhibit HIV-1 replication in dendritic cells and T cells through IFN-α-dependent upregulation of APOBEC3G and 3F.

IFNA7 IFNA14 IFNA16

5.54e-061395322739040
Pubmed

IFN-α directly promotes programmed cell death-1 transcription and limits the duration of T cell-mediated immunity.

IFNA7 IFNA14 IFNA16

5.54e-061395321263073
Pubmed

Interferon alpha-mediated inhibition of human immunodeficiency virus type 1 provirus synthesis in T-cells.

IFNA7 IFNA14 IFNA16

5.54e-06139538438572
Pubmed

Interferon alpha promotes caspase-8 dependent ultraviolet light-mediated keratinocyte apoptosis via interferon regulatory factor 1.

IFNA7 IFNA14 IFNA16

5.54e-061395338660315
Pubmed

Interferon-alpha and -gamma differentially reduce rapid immature T-cell death by contact with HIV-1 carrier cell clones in vitro.

IFNA7 IFNA14 IFNA16

5.54e-06139539343822
Pubmed

Plasmacytoid dendritic cell-derived type I interferon is crucial for the adjuvant activity of Toll-like receptor 7 agonists.

IFNA7 IFNA14 IFNA16

5.54e-061395320065291
Pubmed

Effects of IFN alpha on late stages of HIV-1 replication cycle.

IFNA7 IFNA14 IFNA16

5.54e-06139539865497
Pubmed

Obstruction of HIV-1 particle release by interferon-alpha occurs before viral protease processing and is independent of envelope glycoprotein.

IFNA7 IFNA14 IFNA16

5.54e-06139539181467
Pubmed

Evidence for a different susceptibility of primate lentiviruses to type I interferons.

IFNA7 IFNA14 IFNA16

5.54e-061395323255800
Pubmed

Alveolar macrophages are the primary interferon-alpha producer in pulmonary infection with RNA viruses.

IFNA7 IFNA14 IFNA16

5.54e-061395317723216
Pubmed

Distinction of mouse interferon-alpha subtypes by polymerase chain reaction utilizing consensus primers and type-specific oligonucleotide probes.

IFNA7 IFNA14 IFNA16

5.54e-06139537523540
Pubmed

Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions.

IFNA7 IFNA14 IFNA16

5.54e-06139537510216
Pubmed

Poly I:C-induced activation of NK cells by CD8 alpha+ dendritic cells via the IPS-1 and TRIF-dependent pathways.

IFNA7 IFNA14 IFNA16

5.54e-061395319635904
Pubmed

Murine coronavirus induces type I interferon in oligodendrocytes through recognition by RIG-I and MDA5.

IFNA7 IFNA14 IFNA16

5.54e-061395320427526
Pubmed

Sequencing and bacterial expression of a novel murine alpha interferon gene.

IFNA7 IFNA14 IFNA16

5.54e-061395318726328
Pubmed

Partial inhibition of human immunodeficiency virus replication by type I interferons: impact of cell-to-cell viral transfer.

IFNA7 IFNA14 IFNA16

5.54e-061395319706714
Pubmed

Distinct signature type I interferon responses are determined by the infecting virus and the target cell.

IFNA7 IFNA14 IFNA16

5.54e-061395318572754
Pubmed

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7.

IFNA7 IFNA14 IFNA16

5.54e-061395315723075
Pubmed

Negative regulation of IFN-alpha/beta signaling by IFN regulatory factor 2 for homeostatic development of dendritic cells.

IFNA7 IFNA14 IFNA16

7.03e-061495314983024
Pubmed

Signal 3 cytokines as modulators of primary immune responses during infections: the interplay of type I IFN and IL-12 in CD8 T cell responses.

IFNA7 IFNA14 IFNA16

7.03e-061495322815848
Pubmed

Guanylate binding protein 4 negatively regulates virus-induced type I IFN and antiviral response by targeting IFN regulatory factor 7.

IFNA7 IFNA14 IFNA16

7.03e-061495322095711
Pubmed

Dual regulatory roles of phosphatidylinositol 3-kinase in IFN signaling.

IFNA7 IFNA14 IFNA16

7.03e-061495318981154
Pubmed

Cytokine gene regulation: regulatory cis-elements and DNA binding factors involved in the interferon system.

IFNA7 IFNA14 IFNA16

7.03e-06149531442307
Cytoband9p22

IFNA7 IFNA14 IFNA16

1.91e-05259539p22
GeneFamilyGlycine receptors

GLRA1 GLRB GLRA3

6.02e-075723868
GeneFamilyPhosphatidylinositol transfer proteins

PITPNM2 PITPNC1

2.32e-0467221151
GeneFamilyInterferons

IFNA7 IFNA14 IFNA16

2.76e-0432723598
GeneFamilyADAMTS like

ADAMTSL1 ADAMTSL3

3.24e-047722947
GeneFamilyZinc fingers MIZ-type

PIAS2 PIAS1

3.24e-04772285
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R5B PPP2R3B

1.59e-0315722696
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB TNFRSF19 GRIN3B DNAI3 STOML3 DNAH7

2.86e-061859565e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellPBMC-Mild-cDC_12|Mild / Compartment, Disease Groups and Clusters

ORC6 GPR153 ABCC11 CDC20 NCAPG2 PROX1

3.23e-06189956946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

MRPL39 ORC6 PPP2R3B CDC20 NCAPG2 TOP2A

3.99e-0619695636ed1918f70b6f5760bb088b15ce422998055cc7
ToppCellmedial-Epithelial-Ciliated-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADGB TNFRSF19 GRIN3B DNAI3 STOML3 DNAH7

4.35e-06199956526002f16bbf61cf086278d45a401cc0b0b757a8
ToppCellmedial-Epithelial-Ciliated|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADGB TNFRSF19 GRIN3B DNAI3 STOML3 DNAH7

4.35e-06199956a2daa42b100c422dc8c04fb7d2ebf54293eef574
ToppCellmedial-2-Epithelial-Ciliated|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADGB TNFRSF19 GRIN3B DNAI3 STOML3 DNAH7

4.35e-06199956c02f04a5aa79ee0cf427f6e94b93ceab38ebbcd7
ToppCellCOVID-19_Severe-immature_Neutrophil|COVID-19_Severe / Disease condition and Cell class

ORM2 ORC6 SYNE2 NCAPG2 TOP2A STOM

4.35e-06199956f82fa9d651e78f9ebbe6264e00a48c54b1786a69
ToppCellCOVID-19_Severe-immature_Neutrophil-|COVID-19_Severe / Disease condition and Cell class

ORM2 ORC6 SYNE2 NCAPG2 TOP2A STOM

4.35e-0619995642ea0c19c455bdb0ae89b428d09c333104c670dc
ToppCelldistal-2-Epithelial-Ciliated|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADGB TNFRSF19 GRIN3B DNAI3 STOML3 DNAH7

4.35e-0619995697b66b82c76c7bc1fcd7da7b94dd2aa2d4d70a60
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|367C / Donor, Lineage, Cell class and subclass (all cells)

PPP2R3B CDC20 NCAPG2 TOP2A F13A1

2.69e-051649550662cd9d21608efacc336e0a582859f3b9a4951d
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_1|390C / Donor, Lineage, Cell class and subclass (all cells)

ORC6 PPP2R3B NCF2 CDC20 TOP2A

3.02e-051689552082b15fc7935a211f1c61506b305af5501a21ad
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

KLHL5 ORC6 GPR153 PITPNC1 TOP2A

3.47e-0517395520889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

KLHL5 ORC6 GPR153 PITPNC1 TOP2A

3.47e-0517395546e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCellCF-Myeloid-Neutrophil|Myeloid / Disease state, Lineage and Cell class

IFRD1 SYNE2 NCF2 TRAF3IP3 IL1RAP

3.67e-051759558020c3a34f77e68e8149f87481fb1dddd2ac675e
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTSL1 LRRK2 GLRA3 IL1RAP ANO3

3.77e-0517695540993c41c1017b53039a337174fc56632b278609
ToppCellCiliated_cells-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ADGB GRIN3B DNAI3 STOML3 DNAH7

4.09e-051799550e6c22de2e3fb0ff23b3301863cf4011c5c59dff
ToppCellRSV-Healthy-0|RSV / Virus stimulation, Condition and Cluster

ORC6 SYNE2 SEC23IP TRAF3IP3 CDC20

4.20e-05180955974044056e2f7e909cb11c6f6ca89e58bf95f7e5
ToppCellAdult-Immune-natural_killer_cell-D175|Adult / Lineage, Cell type, age group and donor

EVL SYNE2 TRAF3IP3 PITPNC1 SFMBT2

4.20e-05180955fc59e28f39e7d4fb1bcc7205202cf39224b70d7b
ToppCellRSV-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

ORC6 SYNE2 SEC23IP TRAF3IP3 CDC20

4.20e-05180955703a1d0f9536af94d56757eb01221878d7b7fe61
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CES1 GRIN3B DNAI3 STOML3 DNAH7

4.42e-05182955975f6275777fc578eba528e50f69891c66ec44ad
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CES1 GRIN3B DNAI3 STOML3 DNAH7

4.42e-05182955f8c28fa76751062c4cfba0db8af1b377f947f739
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

C11orf54 ZBED6 LPCAT3 GCSH NOMO3

4.54e-05183955807d64deaf4e50dccf6f831f88578a6d903c1421
ToppCell10x5'-blood-Lymphocytic_T_CD4-Tregs|blood / Manually curated celltypes from each tissue

EVL SYNE2 TRAF3IP3 OGDH NSD3

4.66e-0518495522c15ce30171c687ab564f4383ae74d38b759272
ToppCellCOVID-cycling-|COVID / Condition, Cell_class and T cell subcluster

ORC6 GLRA3 CDC20 NCAPG2 TOP2A

4.78e-05185955eb74b8d36f7b749e04bc2ed4b36f7e1ac7bb6d5f
ToppCellControl-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

KLHL5 ADAMTSL1 TLL1 ELAPOR1 GAN

4.78e-051859556814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCellCOVID-cycling|COVID / Condition, Cell_class and T cell subcluster

ORC6 GLRA3 CDC20 NCAPG2 TOP2A

4.78e-051859555112f966735fa48f0606adcfd5c0212ad5d3d77a
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

C11orf54 ZBED6 LPCAT3 GCSH NOMO3

4.91e-0518695576cbc3610aedf8c19c17ad5faf6ef5e8980b6af5
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB GRIN3B DNAI3 STOML3 DNAH7

4.91e-0518695576033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ADGB GRIN3B DNAI3 STOML3 DNAH7

5.03e-051879552b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDC20 NCAPG2 SFMBT2 TOP2A F13A1

5.03e-0518795573931a5ea73799095daff100b5f18853c57c74dc
ToppCellCiliated_cells-B-HP_01|World / lung cells shred on cell class, cell subclass, sample id

ADGB GRIN3B DNAI3 STOML3 DNAH7

5.03e-05187955bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCell(7)_Epithelial-F_(Ciliated)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ADGB GRIN3B DNAI3 STOML3 DNAH7

5.16e-051889559a8b9f745eed9f129b6c582f48fbbaaacbebb4b3
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

ADGB GRIN3B DNAI3 STOML3 DNAH7

5.29e-05189955dc440015949a768188c67661b6be63b1ead1a0f0
ToppCellCOVID-19-T_cells-CD8+_T_cells|COVID-19 / group, cell type (main and fine annotations)

EVL SYNE2 TRAF3IP3 PITPNC1 SFMBT2

5.29e-051899552c018d6120f65f0b2704b483bc9da1c0984872e3
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLHL5 TRPC6 PITPNC1 ADAMTSL3 SFMBT2

5.29e-0518995506c44746fa4f02e6e2b3b635cdf2d8dfef3754d3
ToppCellCiliated|World / shred by cell class for parenchyma

ADGB GRIN3B DNAI3 STOML3 DNAH7

5.29e-05189955711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ADGB CES1 DNAI3 STOML3 DNAH7

5.43e-051909559ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|343B / Donor, Lineage, Cell class and subclass (all cells)

ADGB GRIN3B DNAI3 STOML3 DNAH7

5.43e-05190955169e600e95878000acf5d11f813f9028c7249646
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|343B / Donor, Lineage, Cell class and subclass (all cells)

ADGB GRIN3B DNAI3 STOML3 DNAH7

5.43e-051909550cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ADGB CES1 DNAI3 STOML3 DNAH7

5.43e-05190955833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

ADGB GRIN3B DNAI3 STOML3 DNAH7

5.43e-051909557031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellControl-T_cells-CD4+_T_cells|Control / group, cell type (main and fine annotations)

EVL SYNE2 TRAF3IP3 PITPNC1 SFMBT2

5.43e-051909550733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCellCiliated_cells-A|World / lung cells shred on cell class, cell subclass, sample id

ADGB GRIN3B DNAI3 STOML3 DNAH7

5.43e-05190955cd87731aaa7d252424f79cfce9f7931457f17bdf
ToppCellCOVID-19-T_cells|COVID-19 / group, cell type (main and fine annotations)

EVL SYNE2 TRAF3IP3 PITPNC1 TOP2A

5.56e-051919557f64add931b64b8d35836fa6bee9ebab593844d3
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PITPNM2 KLHL5 ADAMTSL1 SYNE2 PITPNC1

5.70e-0519295527ff3621e177e7932dd44dd6baa81551ea75a874
ToppCellLAM-Epithelial-AirwayEpi|LAM / Condition, Lineage and Cell class

ELAPOR1 GRIN3B DNAI3 STOML3 DNAH7

5.70e-051929557404fc65be3b7bd09447725b43fa31819004dfee
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMPRSS13 SLCO1A2 SYNE2 LRRK2 TNFRSF19

5.84e-05193955ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

DIP2B ATR NBEAL1 ZBED6 DENND4C

5.84e-05193955abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellMegakaryocytic-erythropoietic-Megakaryo-cells-Megakaryocyte|World / Lineage, cell class and subclass

ACRBP TRPC6 CDC20 F13A1 STOM

5.84e-05193955352cd442b6e62f09b6d22a139774067873644594
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ADGB CES1 DNAI3 STOML3 DNAH7

5.84e-051939550b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ADGB CES1 DNAI3 STOML3 DNAH7

5.99e-05194955b4ce60c06568123008b1081d644733cb91c28f51
ToppCellCOPD-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

EVL ADAMTSL1 SYNE2 PITPNC1 SFMBT2

5.99e-051949558dcde77767b23e75360adb316cdccf56a00e3726
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ADGB CES1 DNAI3 STOML3 DNAH7

5.99e-051949557a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADAMTSL1 TMPRSS13 TLL1 ELAPOR1 DNAH7

5.99e-051949556b286992d4bb56013c0ea5a7601d3476d806175a
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TMPRSS13 SLCO1A2 SYNE2 LRRK2 STOM

5.99e-051949558ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADGB SLCO1A2 CDC20 DNAH7 TOP2A

6.14e-05195955e525b69145059b66417589601f7109af63730f3a
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADGB GRIN3B DNAI3 STOML3 DNAH7

6.14e-05195955cfcf554b436083179dea1d6fd6e3a800ea2430fe
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB CES1 DNAI3 STOML3 DNAH7

6.14e-0519595534e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ADGB CES1 DNAI3 STOML3 DNAH7

6.14e-051959553486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ADGB CES1 DNAI3 STOML3 DNAH7

6.14e-05195955e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

PITPNM2 KLHL5 SYNE2 PITPNC1 STOM

6.14e-0519595550a193475db1bb1e05b8590225a553688c372c14
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB CES1 DNAI3 STOML3 DNAH7

6.14e-0519595507a6bcef6af93ed87df455dee624037cb75e011a
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-T4_reg-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EVL NBEAL1 SYNE2 TRAF3IP3 NSD3

6.14e-05195955911a37684c1f93d537f51ee71cb1ccec06840315
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_1|343B / Donor, Lineage, Cell class and subclass (all cells)

ORC6 CDC20 NCAPG2 TOP2A F13A1

6.14e-0519595547a01b8a92eebeb34ac7f70bf1ab4613a326e24f
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB CES1 DNAI3 STOML3 DNAH7

6.44e-0519795571fea4aa6ce96c7693fa94792d08770622873850
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ELAPOR1 CDC20 DNAI3 DNAH7 TOP2A

6.44e-05197955861e8df9bd74dc5e17bafdc1fb3fef546753c73a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB SYNE2 GRIN3B DNAI3 DNAH7

6.44e-0519795574a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellwk_20-22-Epithelial-Proximal_epithelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADGB GRIN3B DNAI3 STOML3 DNAH7

6.60e-0519895516c54b884500066ade05a406915f9569ca8abdfc
ToppCellTransverse-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

ORC6 CDC20 IL22RA1 NCAPG2 TOP2A

6.75e-051999557cfe9b2538ea008d67343f3e8bfec3bf81200de6
ToppCelldistal-Epithelial-Ciliated-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADGB GRIN3B DNAI3 STOML3 DNAH7

6.75e-051999552de1fe124737a6cca4b3805ab3056f9d9d7c16c7
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ORC6 SYNE2 CDC20 NCAPG2 TOP2A

6.75e-05199955305a9ade5bbe8e981e7c641c9a5e0c9f8ef60470
ToppCelldistal-Epithelial-Ciliated|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADGB GRIN3B DNAI3 STOML3 DNAH7

6.75e-0519995518ca031cfe702afb9bf94e03c0f3680c38e7599e
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ORC6 SYNE2 CDC20 NCAPG2 TOP2A

6.75e-05199955101f78fe6dd1bf9e2e4dd5ad8a970312b3540927
ToppCelldistal-1-Epithelial-Ciliated|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADGB GRIN3B DNAI3 STOML3 DNAH7

6.75e-051999554120e4a2bc05adebe1e1e9670ed7ea55142eb83d
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ORC6 SYNE2 CDC20 NCAPG2 TOP2A

6.75e-05199955e0fcec796afe75e42467ca86355b9fc5aa9ae0a1
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-neutrophil-neutrophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ORM2 IFRD1 SYNE2 LRRK2 NCF2

6.75e-0519995586f2857ce60fbe59375411373ff49c684fd66ad0
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ORC6 SYNE2 CDC20 NCAPG2 TOP2A

6.75e-05199955fba48342066aab41a8bcb20db40a6df0158e1cbe
ToppCellTransverse-T_cell-Tfh|T_cell / Region, Cell class and subclass

PITPNM2 RNF103 ADAMTSL3 IL1RAP NCAPG2

6.75e-0519995533ffea12b8228e0b5bd8942531c3b21d24224725
ToppCell(1)_T_cell-(18)_cycling_gd_T|(1)_T_cell / shred on Cell_type and subtype

ORC6 CDC20 IL22RA1 NCAPG2 TOP2A

6.75e-051999559369d0e4efe809e3e8757294ebebba5a47b30528
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Neuronal-Ventral_Precursors|6_mon / Sample Type, Dataset, Time_group, and Cell type.

PDGFRA ORC6 CDC20 NCAPG2 TOP2A

6.92e-05200955c8ea0db79b1521f8c90d0d749280c354d3907c3a
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell|2m / Sample Type, Dataset, Time_group, and Cell type.

ORC6 SYNE2 CDC20 NCAPG2 TOP2A

6.92e-052009550d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADGB GRIN3B DNAI3 STOML3 DNAH7

6.92e-0520095531d75c26055177d656df1fbb10b764cebd61e122
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Proliferating-Cycling_Progenitors_nGenesUnder4k|6_mon / Sample Type, Dataset, Time_group, and Cell type.

PDGFRA ORC6 CDC20 NCAPG2 TOP2A

6.92e-052009558223d2c9b9e05b1d26e3de1bc0226d175af2e7b2
ToppCellBiopsy_Other_PF-Epithelial-Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

ADGB GRIN3B DNAI3 STOML3 DNAH7

6.92e-05200955721371698bce8890853fb6b6b01a2c20293b39e9
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells|2m / Sample Type, Dataset, Time_group, and Cell type.

ORC6 SYNE2 CDC20 NCAPG2 TOP2A

6.92e-052009550675f580ccef705875854247bbfd4ee2bcf126a1
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ORC6 SYNE2 CDC20 NCAPG2 TOP2A

6.92e-05200955dd5b753bb1333fa502b9d3a6d65a53a9882b2451
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ADGB GRIN3B DNAI3 STOML3 DNAH7

6.92e-052009555abd6d81e1cc354484ae693fcd708d78926e75b5
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADGB GRIN3B DNAI3 STOML3 DNAH7

6.92e-05200955e1dce91c6c531bb212002a14705e496d77ad3490
ToppCellcontrol-gd_T|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

EVL IFRD1 SYNE2 PITPNC1 STOM

6.92e-05200955b188f2acb9bd4f5f1ad4c3d3ddb9a55854a8b74b
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ADGB GRIN3B DNAI3 STOML3 DNAH7

6.92e-052009559c9d2b0276c7b0709c2eeeb0673a2f58106fb14e
ToppCellMS-IIF-Lymphocyte-T/NK-T/NK_proliferative|IIF / Disease, condition lineage and cell class

MRPL39 ORC6 CDC20 NCAPG2 TOP2A

6.92e-05200955c7c1806a1054b2b034a26a18aac93fc3bec4dbc8
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ADGB GRIN3B DNAI3 STOML3 DNAH7

6.92e-05200955ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Ciliated|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

ADGB GRIN3B DNAI3 STOML3 DNAH7

6.92e-05200955a521cf837cadf280505ff9d7e641a205af7d6513
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADGB GRIN3B DNAI3 STOML3 DNAH7

6.92e-05200955918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Intermediate|3m / Sample Type, Dataset, Time_group, and Cell type.

PPP2R5B MYCBP2 NBEAL1 ELAPOR1 PIAS1

6.92e-05200955cbd0b9188a94778ffa539912aeb2a4378f0ab88f
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Ccnb1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PDGFRA CDC20 TOP2A STOM

1.68e-04129954ff74d159034a09f7b174da18bfb9a26936252b4c
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-9|TCGA-Brain / Sample_Type by Project: Shred V9

KLHL5 GAN ADAMTSL3 DNAH7

1.94e-041349542647453f44b0e0a8f27ef9bba750e99eb40efc8b
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

EVL CES1 GPR153 TNFRSF19

2.36e-04141954399380de5ea09e22fd128e3e55fffeffc4874c15
ToppCell356C-Epithelial_cells-Epithelial-C_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MRPL39 GCSH METTL23 RNF17

2.49e-04143954b74571d30def54a0524c8d95a3bc9d3439319eb4
ToppCell356C-Epithelial_cells-Epithelial-C_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MRPL39 GCSH METTL23 RNF17

2.49e-041439545c81b238be53f010d691d0c59c1c29cb52222ed3
ComputationalNeurotransmitter (GABA) receptor.

GLRA1 GLRB GLRA3

6.82e-0515593MODULE_215
ComputationalGenes in the cancer module 141.

SLC12A3 GLRA1 GLRB

8.36e-0516593MODULE_141
ComputationalNeighborhood of MLLT10

PPP2R5B ADAM20 TLL1 GLRA3 ARFGEF2 ADAMTSL3 PIAS2 IFNA14

2.26e-04302598MORF_MLLT10
ComputationalNeighborhood of PTPRR

ADAM20 TLL1 GLRA3 ADAMTSL3 IFNA14

2.33e-04102595MORF_PTPRR
ComputationalIon channels.

GLRA1 GLRB GLRA3

4.18e-0427593MODULE_214
ComputationalNeighborhood of CTSB

ADAM20 TLL1 GLRA3 ARFGEF2 ADAMTSL3 IFNA14

5.36e-04187596MORF_CTSB
DrugPK 8165

ORM2 GLRA1 GLRB GLRA3

9.86e-097954CID000071219
DrugGlycine

GLRA1 GLRB GLRA3 GRIN3B GCSH

1.49e-0730955DB00145
Drugiso-THAZ

GLRA1 GLRB GLRA3

2.81e-074953CID003047783
Drugprotostrychnine

GLRA1 GLRB GLRA3

2.81e-074953CID005320746
Drug7-nitroindoline

GLRA1 GLRB GLRA3

2.81e-074953CID013566747
Drug2-(phosphonomethyl)phenylalanine

GLRA1 GLRB GLRA3

2.81e-074953CID000383689
DrugSC-49648

GLRA1 GLRB GLRA3

2.81e-074953CID000195696
Drugakuammiline

GLRA1 GLRB GLRA3

2.81e-074953CID005367018
DrugNSC381080

GLRA1 GLRB GLRA3

2.81e-074953CID000165497
DrugN-methyl-THIP

GLRA1 GLRB GLRA3

2.81e-074953CID000134373
DrugSC-48981

GLRA1 GLRB GLRA3

2.81e-074953CID000126573
DrugSC-50132

GLRA1 GLRB GLRA3

2.81e-074953CID000195719
DrugSR 42641

GLRA1 GLRB GLRA3

2.81e-074953CID000129049
DrugACEA-1011

GLRA1 GLRB GLRA3 GRIN3B

3.75e-0715954CID000127872
DrugLY233536

GLRA1 GLRB GLRA3 GRIN3B

4.98e-0716954CID000126239
Drug7-Cl-Thio-Kyna

GLRA1 GLRB GLRA3 GRIN3B

6.49e-0717954CID003035668
Drugazetidine-3-carboxylic acid

GLRA1 GLRB GLRA3

6.99e-075953CID000093192
DrugLindane

GLRA1 GLRB GLRA3

6.99e-075953DB00431
DrugCao C

GLRA1 GLRB GLRA3

6.99e-075953CID000166617
Drugoxanilide

GLRA1 GLRB GLRA3

6.99e-075953CID000069288
Drugiso-THAO

GLRA1 GLRB GLRA3

6.99e-075953CID000127199
DrugALX1393

GLRA1 GLRB GLRA3

6.99e-075953CID016078939
Drugpleiocarpamine

GLRA1 GLRB GLRA3

6.99e-075953CID000558637
Drugmafoprazine

GLRA1 GLRB GLRA3

6.99e-075953CID000071241
Druggevotroline

GLRA1 GLRB GLRA3

6.99e-075953CID000060546
DrugMNQX

GLRA1 GLRB GLRA3 GRIN3B

8.32e-0718954CID000130818
DrugTHAZ

GLRA1 GLRB GLRA3

1.39e-066953CID000171289
DrugmV GABA

GLRA1 GLRB GLRA3

1.39e-066953CID000128435
Drugcaged glycine

GLRA1 GLRB GLRA3

1.39e-066953CID000192642
Drugbrometone

GLRA1 GLRB GLRA3

1.39e-066953CID000006424
Drugminaxolone

GLRA1 GLRB GLRA3

1.39e-066953CID000071960
Drugthiomuscimol

GLRA1 GLRB GLRA3

1.39e-066953CID000005448
Drugthio-THIP

GLRA1 GLRB GLRA3

1.39e-066953CID000656720
DrugAC1L90PQ

GLRA1 GLRB GLRA3

1.39e-066953CID000436036
Drugalpha-EMTBL

GLRA1 GLRB GLRA3

2.43e-067953CID000128423
DrugCID189778

GLRA1 GLRB GLRA3

2.43e-067953CID000189778
Drugpropyl methanethiosulfonate

GLRA1 GLRB GLRA3

2.43e-067953CID000529387
Drugthiocolchicoside

GLRA1 GLRB GLRA3

2.43e-067953CID000072067
DrugL-serinamide

GLRA1 GLRB GLRA3

2.43e-067953CID000101138
DrugBoc-glycine

GLRA1 GLRB GLRA3

2.43e-067953CID000078288
DrugSL 75102

ORM2 GLRA1 GLRB GLRA3

2.83e-0624954CID005751746
DrugWT702

GLRA1 GLRB GLRA3

3.88e-068953CID000089643
Drugisostrychnine

GLRA1 GLRB GLRA3

3.88e-068953CID000264626
DrugL-689,560

GLRA1 GLRB GLRA3 GRIN3B

4.64e-0627954CID000121918
DrugAtonik

GLRA1 GLRB GLRA3

5.80e-069953CID000069471
Drugnortropanol

GLRA1 GLRB GLRA3

5.80e-069953CID000068147
DrugAC1NSJX8

GLRA1 GLRB GLRA3

5.80e-069953CID005311059
DrugNSC129536

GLRA1 GLRB GLRA3

5.80e-069953CID000004815
DrugSR 57227A

GLRA1 GLRB GLRA3

5.80e-069953CID000131746
DrugDCQX

GLRA1 GLRB GLRA3

5.80e-069953CID000001845
DrugAC1NUW3V

GLRA1 GLRB GLRA3 GRIN3B

6.24e-0629954CID005462126
DrugLY235959

GLRA1 GLRB GLRA3 GRIN3B

8.21e-0631954CID000131938
DrugNPC 12626

GLRA1 GLRB GLRA3 GRIN3B

8.21e-0631954CID000108099
Drugeliprodil

GLRA1 GLRB GLRA3 GRIN3B

8.21e-0631954CID000060703
DrugTHBA

GLRA1 GLRB GLRA3

8.27e-0610953CID000130993
DrugL-cycloserine

GLRA1 GLRB GLRA3 GRIN3B OGDH

8.31e-0666955CID000000401
Drug1-aminocyclopropane-1-carboxylic acid

PDGFRA GLRA1 GLRB GLRA3 ADI1 GRIN3B

8.35e-06114956CID000000535
Drugindole-2-carboxylic acid

GLRA1 GLRB GLRA3 GRIN3B

9.35e-0632954CID000072899
Drugip 0

GLRA1 GLRB GLRA3

1.13e-0511953CID000006943
Drugcolchicoside

GLRA1 GLRB GLRA3

1.51e-0512953CID000092763
DrugC6H12NO5P

GLRA1 GLRB GLRA3 GRIN3B

1.51e-0536954CID000104962
DrugNSC-88789

GLRA1 GLRB GLRA3 GRIN3B

2.09e-0539954CID000002748
DrugHA-966

GLRA1 GLRB GLRA3 GRIN3B

2.09e-0539954CID000001232
DrugABPH

GLRA1 GLRB GLRA3

2.48e-0514953CID000092377
Drugquinoxaline-2,3-dione

GLRA1 GLRB GLRA3

2.48e-0514953CID011469229
Drugmilacemide

GLRA1 GLRB GLRA3

3.09e-0515953CID000053568
Drug7-chlorokynurenic acid

GLRA1 GLRB GLRA3 GRIN3B

3.72e-0545954CID000001884
Drugzatosetron

GLRA1 GLRB GLRA3

4.59e-0517953CID000060763
Drugavermectin

GLRA1 GLRB BCKDHB GRIN3B

4.81e-0548954CID006450460
Drugcyanotriphenylborate

GLRA1 GLRB

5.15e-053952CID000151925
Drug7-chloro-4-quinolinol

GLRA1 GLRB

5.15e-053952CID000066593
Drug5,7-dichlorokynurenic acid

GLRA1 GLRB GLRA3 GRIN3B

5.22e-0549954CID000001779
DrugAC1L1CMQ

GLRA1 GLRB GLRA3

6.50e-0519953CID000001968
DrugPNU-120596

GLRA1 GLRB GLRA3

6.50e-0519953CID000311434
Drugpropanethiol

GLRA1 GLRB GLRA3

7.62e-0520953CID000007848
Drugdi-Z

GLRA1 GLRB GLRA3

7.62e-0520953CID000656933
Drugglycine

GLRA1 GLRB GLRA3 GRIN3B GCSH PIAS1

7.71e-05169956CID000000750
Drugethyltrimethylammonium

GLRA1 GLRB GLRA3

8.86e-0521953CID000033993
Drugmeproadifen

GLRA1 GLRB GLRA3

8.86e-0521953CID000189752
DrugR 5135

GLRA1 GLRB GLRA3

8.86e-0521953CID000119544
Drugnipecotic acid

SLCO1A2 GLRA1 GLRB GLRA3

9.48e-0557954CID000004498
DrugZ-Gly

GLRA1 GLRB GLRA3

1.02e-0422953CID000014349
Drug2-hydroxysaclofen

GLRA1 GLRB GLRA3 GRIN3B

1.09e-0459954CID000001564
Drugmagnesium oxide

SLC12A3 GAN STOML3

1.17e-0423953CID000014792
DrugCGP 35348

GLRA1 GLRB GLRA3 GRIN3B

1.32e-0462954CID000107699
Drug1-chloro-1,2,2-trifluorocyclobutane

GLRA1 GLRB GLRA3

1.34e-0424953CID000079091
Drugdimethyl succinate

CES1 EHMT1 BCKDHB

1.34e-0424953CID000007820
DrugAP-7

GLRA1 GLRB GLRA3 GRIN3B

1.40e-0463954CID000003122
DrugAmpyrone [83-07-8]; Down 200; 19.6uM; PC3; HT_HG-U133A

GLRB SEC23IP ARFGEF2 BCKDHB STOM NSD3

1.64e-041949562086_DN
DrugV-X-A

GLRA1 GLRB GLRA3

1.71e-0426953CID006369389
DrugPF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A

LPCAT3 GLRB GAN BCKDHB IL1RAP IL22RA1

1.83e-041989566907_UP
DrugRanitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A

ADGB SLC12A3 GPR153 GLRA3 RNF17 PIAS2

1.83e-041989565425_UP
DrugNeomycin sulfate [1405-10-3]; Up 200; 4.2uM; HL60; HG-U133A

ORM2 PCNX4 SEC23IP NCF2 IL1RAP NSD3

1.88e-041999561383_UP
Drugenflurane

GLRA1 GLRB GLRA3 GRIN3B

1.89e-0468954CID000003226
Drugpitrazepin

GLRA1 GLRB GLRA3

1.91e-0427953CID000146222
Drugphaclofen

GLRA1 GLRB GLRA3 GRIN3B

2.11e-0470954CID000001641
Drugfelbamate

GLRA1 GLRB GLRA3 GRIN3B

2.11e-0470954CID000003331
DrugBN52020

GLRA1 GLRB GLRA3

2.14e-0428953CID000115221
Drugpentylenetetrazol

GLRA1 GLRB GLRA3 GRIN3B OGDH

2.16e-04130955CID000005917
Drugifenprodil

GLRA1 GLRB GLRA3 GRIN3B

2.23e-0471954CID000003689
DiseaseHereditary hyperekplexia

GLRA1 GLRB

9.35e-055912cv:C1835614
DiseaseX-23756 measurement

SLCO1B7 SLCO1A2

9.35e-055912EFO_0022126
Diseaseviral infectious disease (implicated_via_orthology)

PTPRQ EHMT1

9.35e-055912DOID:934 (implicated_via_orthology)
DiseaseHereditary Hyperexplexia

GLRA1 GLRB

9.35e-055912C1835614
DiseaseHyperekplexia

GLRA1 GLRB

1.40e-046912cv:C0234166
Diseasehexadecenedioate (C16:1-DC) measurement

SLCO1B7 SLCO1A2

3.34e-049912EFO_0800562
Diseaseglycochenodeoxycholate glucuronide (1) measurement

SLCO1B7 SLCO1A2

7.18e-0413912EFO_0800474
Diseasehematologic cancer (implicated_via_orthology)

PIAS2 PIAS1

7.18e-0413912DOID:2531 (implicated_via_orthology)
Diseasemyeloid leukemia (is_implicated_in)

PDGFRA NSD3

7.18e-0413912DOID:8692 (is_implicated_in)
Diseasecathepsin L1 measurement

ADGB LRRK2

1.10e-0316912EFO_0010619
Diseasespine bone size

BCKDHB ADAMTSL3

1.39e-0318912EFO_0004508
DiseaseTourette syndrome, schizophrenia

PITPNM2 NSD3

1.39e-0318912EFO_0004895, MONDO_0005090
DiseaseChronic myeloproliferative disorder

ATR ORC6

1.55e-0319912C1292778
DiseaseSeckel syndrome

ATR ORC6

2.09e-0322912C0265202
DiseaseRenal glomerular disease

SLC12A3 TRPC6

2.28e-0323912C0268731
DiseaseGlomerulopathy Assessment

SLC12A3 TRPC6

2.28e-0323912C4521256

Protein segments in the cluster

PeptideGeneStartEntry
LKYWPKTCTQKEVMF

PPP2R5B

321

Q15173
KTAMSLLWKSYPLVC

CES1

376

P23141
VIWKYPTMAKVAELK

CDC20

426

Q12834
VSKMCPSDVYRVWKR

ANKRD13D

136

Q6ZTN6
VEWLDVKYCMPTSDK

ADGB

886

Q8N7X0
IVGTTYVKCWTPDIM

ADAM20

546

O43506
TCIITPTAKAWKYME

ACRBP

336

Q8NEB7
LCIPRSDVMYTDWKK

ORM2

166

P19652
LKCMVEWSKDLYVNP

ARFGEF2

571

Q9Y6D5
EKMITCVSWHPTIYG

DNAI3

336

Q8IWG1
KKFKLPVWETIVCTM

AIP

66

O00170
MFIKIHIPWDTLCKY

ANO3

206

Q9BYT9
RLFELWMLYCTKKDP

NBEAL1

6

Q6ZS30
KTIHWIKAPNYSCVM

RAE1

131

P78406
LPGKYKISIMHEDWC

NOMO3

551

P69849
DKKTPTSIEYWFRCM

PPP2R3B

386

Q9Y5P8
SLPKVSYVKAIDIWM

GLRA3

306

O75311
PEYDIMCKVKSWVID

OLA1

181

Q9NTK5
IPDKWKCYDALRKMI

BCKDHB

376

P21953
YEIMVKCWNSEPEKR

PDGFRA

926

P16234
LPGKYKISIMHEDWC

NOMO2

551

Q5JPE7
TLYLMEKKYSPCAWE

IFNA14

151

P01570
KAMECVWKQKLYEPV

NCF2

161

P19878
VKPTITWYMGCYKIQ

IL1RAP

171

Q9NPH3
GETQLMYKWAKPKIC

ELAPOR1

346

Q6UXG2
HVTSVEEWKCMYTPK

ADAMTSL1

411

Q8N6G6
WILVQYCSKRPGMKE

PCNX4

766

Q63HM2
IAICKPLWYTMILTS

OR52E6

126

Q96RD3
VAICKPLSYTTIMNW

OR4X2

116

Q8NGF9
ASVMVYDDTSKKWVP

EVL

11

Q9UI08
MVCWPVNYRLSNAKK

GPR153

111

Q6NV75
TLYLMEKKYSPCAWE

IFNA7

151

P01567
LTCIKLIKMYTWEKP

ABCC11

346

Q96J66
LPGKYKISIMHEDWC

NOMO1

551

Q15155
YSVMKTCPLSWVQRV

DIP2B

586

Q9P265
YFVEPKWLCKIMAQI

LRRK2

1596

Q5S007
NYDIKWTMPHCVLTL

LPCAT3

136

Q6P1A2
PKCIVGKFRMYVAVW

F13A1

151

P00488
YKWDMKCVHIPLESF

METTL23

146

Q86XA0
KSCYEDGWLIKMTLS

GCSH

136

P23434
DALTVDPTMYKCLWK

GLRB

126

P48167
WIEEYKKQVFPIMCA

PITPNM2

176

Q9BZ72
VECYNPKTKTWSVMP

KLHL5

531

Q96PQ7
TPCDEEGKTQIMYKW

ELAPOR2

356

A8MWY0
IMYKWIEPKICREDL

ELAPOR2

366

A8MWY0
YIVKYKEVCPWMQTV

PTPRQ

131

Q9UMZ3
MYCAWLENPKSVHKS

OGDH

61

Q02218
KKPSVVITWMSLDFY

ATR

526

Q13535
IMKKYKDVTACLPEW

ATR

2021

Q13535
MECYDIYSKTWTKQP

GAN

391

Q9H2C0
YDTVPVMWLKPCKRA

DNAH7

3951

Q8WXX0
MWGSSVFLCYKKSVP

DENND4C

186

Q5VZ89
IKFGPERMYIDCWVK

IFRD1

356

O00458
IMICVPTWAKESAPY

IL22RA1

201

Q8N6P7
PTWAKESAPYMCRVK

IL22RA1

206

Q8N6P7
TDYIKNLPMWRFKCL

RNF103

506

O00237
PMIWATEYKHVDLVK

EHMT1

876

Q9H9B1
ALYLQMNEKKPTWIC

PIAS2

371

O75928
KWYKMVPCGKRVFAV

GRIN3B

806

O60391
SWNILCKIIMAAYPA

TAS2R40

276

P59535
AVKTLPTEAMWKCYI

UTP6

316

Q9NYH9
QPWDMYKPLTKSCEI

MRPL39

111

Q9NYK5
YNMVPPKVKCLTKIW

UBE2F

91

Q969M7
KVWKISLQGPCYMTL

TMCO3

346

Q6UWJ1
LVDWKKYHLCMIPNL

TOP6BL

276

Q8N6T0
DYRPMKECVWKITVS

TLL1

481

O43897
FWYCMEHSKPVVLSL

SYNE2

5296

Q8WXH0
TLYLMGKKYSPCAWE

IFNA16

151

P05015
ICNPLLYTVTMSWKV

OR5L1

126

Q8NGL2
SLPKVSYVKAIDIWM

GLRA1

301

P23415
DVDPSWKKAIYKVIC

PROX1

701

Q92786
HYKVTFPECVRWMTI

MYCBP2

2036

O75592
ASWMKCPLDRAYLIK

ORC6

56

Q9Y5N6
PSECTKEVKSLMWVY

SLCO1A2

146

P46721
CKEVEYKQLWMPFSV

SEC23IP

276

Q9Y6Y8
PIYFGALIDTTCMKW

SLCO1B7

541

G3V0H7
LYIQMNEKKPTWVCP

PIAS1

361

O75925
YLTCKNGEWKPAMEI

SUSD6

86

Q92537
FPISIWMCIKIIKEY

STOM

46

P27105
GILGVCKITSKYWEM

NCAPG2

396

Q86XI2
CKITSKYWEMMPPTI

NCAPG2

401

Q86XI2
AAKFWKICPMEHILV

NCAPG2

491

Q86XI2
KWLHFYEMKAPLVCL

C11orf54

236

Q9H0W9
CKLAYIEPYKRTMQW

RNF17

791

Q9BXT8
CTQKYSPWGMKKVLL

TRAF3IP3

256

Q9Y228
KVTEVLPWIYSKMEV

TMPRSS13

546

Q9BYE2
ITFPISIWMCLKIIK

STOML3

41

Q8TAV4
PSEIYPLKMASEWKC

SFMBT2

256

Q5VUG0
MCSYKLVTVKFEVWG

PITPNC1

181

Q9UKF7
RKGKCPSSLYMAWLE

SLC12A3

981

P55017
MLGTKHSYWICKPAE

TTLL2

201

Q9BWV7
MAPVSPEYWSKIKCK

NSD3

1411

Q9BZ95
MPLWYLTKEKKDELC

TOP2A

1131

P11388
QWTLMTYVCDILKPF

ZBED6

681

P86452
IYCKRQFMEKKPSWS

TNFRSF19

191

Q9NS68
ALIYWFAPCSKMGKI

TRPC6

421

Q9Y210
MFTYNIPTCLATWKI

ZFC3H1

1896

O60293
PAICKSYLKLMTELW

USP33

226

Q8TEY7
QVEEWKCMYAPKPKV

ADAMTSL3

456

P82987
YSWMDIITICKDKLP

ADI1

61

Q9BV57