Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	acetylspermidine deacetylase activity	HDAC6 HDAC10	1.01e-05	2	64	2	GO:0047611
GeneOntologyBiologicalProcess	spermidine deacetylation	HDAC6 HDAC10	9.48e-06	2	64	2	GO:0106048
GeneOntologyBiologicalProcess	polyamine deacetylation	HDAC6 HDAC10	9.48e-06	2	64	2	GO:0106047
GeneOntologyBiologicalProcess	positive regulation of synaptic transmission, glutamatergic	RELN HDAC6 EGFR GLUL	9.50e-06	43	64	4	GO:0051968
GeneOntologyBiologicalProcess	positive regulation of DNA metabolic process	UBE2B WIZ EGFR UBE2V2 SMARCA2 INO80 HDAC10	7.57e-05	333	64	7	GO:0051054
GeneOntologyBiologicalProcess	positive regulation of DNA repair	EGFR UBE2V2 SMARCA2 INO80 HDAC10	8.19e-05	143	64	5	GO:0045739
GeneOntologyBiologicalProcess	regulation of bile acid secretion	CES1 ABCB11	1.41e-04	6	64	2	GO:0120188
GeneOntologyBiologicalProcess	anatomical structure formation involved in morphogenesis	RELN COL12A1 SLC24A4 NEBL CLASP1 GLUL LRP2 RNF213 SALL4 PLCD1 FUT1 DYSF ENPEP EPHA1	1.47e-04	1483	64	14	GO:0048646
GeneOntologyBiologicalProcess	response to UV	UBE2A UBE2B EGFR INO80 CERS1	1.70e-04	167	64	5	GO:0009411
GeneOntologyBiologicalProcess	regulation of synaptic transmission, glutamatergic	RELN HDAC6 EGFR GLUL	1.92e-04	92	64	4	GO:0051966
GeneOntologyBiologicalProcess	positive regulation of nuclear cell cycle DNA replication	WIZ INO80	1.97e-04	7	64	2	GO:0010571
GeneOntologyBiologicalProcess	negative regulation of microtubule depolymerization	HDAC6 CLASP1 DYSF	2.22e-04	38	64	3	GO:0007026
GeneOntologyBiologicalProcess	postreplication repair	UBE2A UBE2B UBE2V2	2.22e-04	38	64	3	GO:0006301
GeneOntologyBiologicalProcess	protein polyubiquitination	UBE2A UBE2B HDAC6 UBE2V2 RNF213 DYSF	2.72e-04	289	64	6	GO:0000209
GeneOntologyBiologicalProcess	regulation of microtubule depolymerization	HDAC6 CLASP1 DYSF	3.00e-04	42	64	3	GO:0031114
GeneOntologyBiologicalProcess	carbon catabolite regulation of transcription from RNA polymerase II promoter	SIK2 NCOA1	3.36e-04	9	64	2	GO:0000429
GeneOntologyBiologicalProcess	spermidine metabolic process	HDAC6 HDAC10	3.36e-04	9	64	2	GO:0008216
GeneOntologyBiologicalProcess	regulation of DNA metabolic process	UBE2B WIZ EGFR UBE2V2 SMARCA2 INO80 CERS1 HDAC10	3.42e-04	564	64	8	GO:0051052
GeneOntologyBiologicalProcess	regulation of autophagy of mitochondrion	UBE2A HDAC6 CERS1	3.68e-04	45	64	3	GO:1903146
GeneOntologyBiologicalProcess	cellular catabolic process	TRHDE ERFE UBE2A HDAC6 CES1 GLUL ABCB11 RNF213 CERS1 HDAC10 ENPEP PLBD2	4.15e-04	1253	64	12	GO:0044248
GeneOntologyBiologicalProcess	carbon catabolite regulation of transcription	SIK2 NCOA1	4.20e-04	10	64	2	GO:0045990
GeneOntologyCellularComponent	ubiquitin conjugating enzyme complex	UBE2A UBE2B UBE2V2	2.27e-06	9	64	3	GO:0031371
GeneOntologyCellularComponent	HULC complex	UBE2A UBE2B	5.51e-05	4	64	2	GO:0033503
Domain	UQ_con	UBE2A UBE2B UBE2V2	2.92e-04	39	62	3	PF00179
Domain	ERAP1-like_C_dom	TRHDE ENPEP	3.00e-04	8	62	2	IPR024571
Domain	ERAP1_C	TRHDE ENPEP	3.00e-04	8	62	2	PF11838
Domain	ZINC_PROTEASE	TRHDE MMP24 ADAM21 ENPEP	3.15e-04	98	62	4	PS00142
Domain	UBIQUITIN_CONJUGAT_1	UBE2A UBE2B UBE2V2	3.15e-04	40	62	3	PS00183
Domain	UBQ-conjugat_E2	UBE2A UBE2B UBE2V2	3.39e-04	41	62	3	IPR000608
Domain	UBIQUITIN_CONJUGAT_2	UBE2A UBE2B UBE2V2	3.39e-04	41	62	3	PS50127
Domain	Hist_deacetyl	HDAC6 HDAC10	5.85e-04	11	62	2	PF00850
Domain	His_deacetylse_dom	HDAC6 HDAC10	5.85e-04	11	62	2	IPR023801
Domain	-	HDAC6 HDAC10	5.85e-04	11	62	2	3.40.800.20
Domain	His_deacetylse	HDAC6 HDAC10	5.85e-04	11	62	2	IPR000286
Domain	-	UBE2A UBE2B UBE2V2	6.48e-04	51	62	3	3.10.110.10
Domain	Peptidase_M1	TRHDE ENPEP	7.00e-04	12	62	2	IPR001930
Domain	UBQ-conjugating_enzyme/RWD	UBE2A UBE2B UBE2V2	7.25e-04	53	62	3	IPR016135
Domain	Peptidase_M1	TRHDE ENPEP	8.26e-04	13	62	2	PF01433
Domain	Peptidase_M1_N	TRHDE ENPEP	8.26e-04	13	62	2	IPR014782
Domain	VWA	COL12A1 COL6A6 VWA8	8.52e-04	56	62	3	PF00092
Domain	ATPase_dyneun-rel_AAA	DNAH10 VWA8	9.62e-04	14	62	2	IPR011704
Domain	AAA_5	DNAH10 VWA8	9.62e-04	14	62	2	PF07728
Domain	AAA+_ATPase	DNAH10 VWA8 ABCB11 RNF213	1.34e-03	144	62	4	IPR003593
Domain	AAA	DNAH10 VWA8 ABCB11 RNF213	1.34e-03	144	62	4	SM00382
Domain	fn3	LRFN1 COL12A1 ANKFN1 EPHA1	2.06e-03	162	62	4	PF00041
Domain	VWFA	COL12A1 COL6A6 VWA8	2.56e-03	82	62	3	PS50234
Domain	VWA	COL12A1 COL6A6 VWA8	2.74e-03	84	62	3	SM00327
Domain	UBQ-conjugating_AS	UBE2A UBE2B	3.10e-03	25	62	2	IPR023313
Domain	FN3	LRFN1 COL12A1 ANKFN1 EPHA1	3.32e-03	185	62	4	SM00060
Domain	FN3	LRFN1 COL12A1 ANKFN1 EPHA1	4.31e-03	199	62	4	PS50853
Domain	VWF_A	COL12A1 COL6A6 VWA8	4.36e-03	99	62	3	IPR002035
Domain	SNF2_N	SMARCA2 INO80	5.04e-03	32	62	2	IPR000330
Domain	SNF2_N	SMARCA2 INO80	5.04e-03	32	62	2	PF00176
Domain	FN3_dom	LRFN1 COL12A1 ANKFN1 EPHA1	5.12e-03	209	62	4	IPR003961
Domain	CYSTEINE_SWITCH	MMP24 ADAM21	8.18e-03	41	62	2	PS00546
Domain	Pept_M10_metallopeptidase	MMP24 ADAM21	8.97e-03	43	62	2	IPR001818
Domain	C2	SYTL4 PLCD1 DYSF	9.44e-03	131	62	3	PF00168
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	MMP24 UBE2A UBE2B DNAH10 EGFR TRPM3 CES1 ADAM21 SMARCA2 LRP2 CPD	8.75e-08	730	64	11	34857952
Pubmed	The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice.	UBE2A UBE2B	3.33e-06	2	64	2	15169909
Pubmed	Loss of HR6B ubiquitin-conjugating activity results in damaged synaptonemal complex structure and increased crossing-over frequency during the male meiotic prophase.	UBE2A UBE2B	3.33e-06	2	64	2	12556476
Pubmed	Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.	UBE2A UBE2B	3.33e-06	2	64	2	1717990
Pubmed	Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31.	UBE2A UBE2B	3.33e-06	2	64	2	1559696
Pubmed	Isolation and characterization of mammalian HDAC10, a novel histone deacetylase.	HDAC6 HDAC10	3.33e-06	2	64	2	11677242
Pubmed	The NMR structure of the class I human ubiquitin-conjugating enzyme 2b.	UBE2A UBE2B	3.33e-06	2	64	2	11885984
Pubmed	HDAC6 sustains growth stimulation by prolonging the activation of EGF receptor through the inhibition of rabaptin-5-mediated early endosome fusion in gastric cancer.	HDAC6 EGFR	3.33e-06	2	64	2	25111897
Pubmed	HDAC6-mediated EGFR stabilization and activation restrict cell response to sorafenib in non-small cell lung cancer cells.	HDAC6 EGFR	3.33e-06	2	64	2	27090797
Pubmed	The microtubule-associated histone deacetylase 6 (HDAC6) regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation.	HDAC6 EGFR	3.33e-06	2	64	2	20133936
Pubmed	Alternative Splicing of RAD6B and Not RAD6A is Selectively Increased in Melanoma: Identification and Functional Characterization.	UBE2A UBE2B	3.33e-06	2	64	2	31683936
Pubmed	High-resolution maps of the murine Chromosome 2 region containing the cholesterol gallstone locus, Lith1.	LRP2 ABCB11	3.33e-06	2	64	2	10556425
Pubmed	RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance.	UBE2A UBE2B	3.33e-06	2	64	2	28806395
Pubmed	Histone deacetylase 10 structure and molecular function as a polyamine deacetylase.	HDAC6 HDAC10	3.33e-06	2	64	2	28516954
Pubmed	New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins.	UBE2A UBE2B UBE2V2	3.97e-06	17	64	3	26489670
Pubmed	Linkage of Nat and Es-1 in the mouse and development of strains congenic for N-acetyltransferase.	NAT1 CES1	9.99e-06	3	64	2	3209851
Pubmed	The human RAD18 gene product interacts with HHR6A and HHR6B.	UBE2A UBE2B	9.99e-06	3	64	2	10908344
Pubmed	Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain.	HDAC6 HDAC10	9.99e-06	3	64	2	11861901
Pubmed	Enhanced genomic instability and defective postreplication repair in RAD18 knockout mouse embryonic stem cells.	UBE2A UBE2B	9.99e-06	3	64	2	12509447
Pubmed	UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4.	UBE2A UBE2B	9.99e-06	3	64	2	38182926
Pubmed	Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens.	UBE2A UBE2B	9.99e-06	3	64	2	10884424
Pubmed	RNF168 forms a functional complex with RAD6 during the DNA damage response.	UBE2A UBE2B	9.99e-06	3	64	2	23525009
Pubmed	Faster regeneration associated to high expression of Fam65b and Hdac6 in dysferlin-deficient mouse.	HDAC6 DYSF	9.99e-06	3	64	2	31218594
Pubmed	HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells.	HDAC6 EGFR	9.99e-06	3	64	2	23152903
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	MMP24 WIZ NEBL GLUL LRP2 ABCB11 PLCD1 CFAP70 DYSF ENPEP	1.57e-05	1016	64	10	19056867
Pubmed	A conserved RAD6-MDM2 ubiquitin ligase machinery targets histone chaperone ASF1A in tumorigenesis.	UBE2A UBE2B	2.00e-05	4	64	2	26336826
Pubmed	ZNF198 protein, involved in rearrangement in myeloproliferative disease, forms complexes with the DNA repair-associated HHR6A/6B and RAD18 proteins.	UBE2A UBE2B	2.00e-05	4	64	2	12776193
Pubmed	EGF-induced sodium influx regulates EGFR trafficking through HDAC6 and tubulin acetylation.	HDAC6 EGFR	2.00e-05	4	64	2	26382850
Pubmed	Rad6 overexpression induces multinucleation, centrosome amplification, abnormal mitosis, aneuploidy, and transformation.	UBE2A UBE2B	2.00e-05	4	64	2	11929833
Pubmed	RAD6 promotes homologous recombination repair by activating the autophagy-mediated degradation of heterochromatin protein HP1.	UBE2A UBE2B	2.00e-05	4	64	2	25384975
Pubmed	Gender-associated expression of tumor markers and a small gene set in breast carcinoma.	NAT1 EGFR	2.00e-05	4	64	2	24656773
Pubmed	RAD6 regulates the dosage of p53 by a combination of transcriptional and posttranscriptional mechanisms.	UBE2A UBE2B	2.00e-05	4	64	2	22083959
Pubmed	Mutations of Rad6 E2 ubiquitin-conjugating enzymes at alanine-126 in helix-3 affect ubiquitination activity and decrease enzyme stability.	UBE2A UBE2B	2.00e-05	4	64	2	36162503
Pubmed	A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.	UBE2A UBE2B HDAC6 UBE2V2	2.16e-05	88	64	4	27182664
Pubmed	Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination.	UBE2A UBE2B	3.32e-05	5	64	2	15359278
Pubmed	The mouse homolog to the ras-related yeast gene YPT1 maps on chromosome 11 close to the wobbler (wr) locus.	EGFR GLUL	3.32e-05	5	64	2	1643310
Pubmed	Deactylase inhibitors disrupt cellular complexes containing protein phosphatases and deacetylases.	HDAC6 HDAC10	3.32e-05	5	64	2	14670976
Pubmed	Fam65b is important for formation of the HDAC6-dysferlin protein complex during myogenic cell differentiation.	HDAC6 DYSF	3.32e-05	5	64	2	24687993
Pubmed	Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks.	UBE2A UBE2B	3.32e-05	5	64	2	18363965
Pubmed	Ubiquitin ligase Rad18Sc localizes to the XY body and to other chromosomal regions that are unpaired and transcriptionally silenced during male meiotic prophase.	UBE2A UBE2B	4.98e-05	6	64	2	15383616
Pubmed	NBS1 recruits RAD18 via a RAD6-like domain and regulates Pol η-dependent translesion DNA synthesis.	UBE2A UBE2B	4.98e-05	6	64	2	21884979
Pubmed	Role of E2-RING Interactions in Governing RNF4-Mediated Substrate Ubiquitination.	UBE2A UBE2B	4.98e-05	6	64	2	27678051
Pubmed	Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen.	UBE2A UBE2V2	4.98e-05	6	64	2	17108083
Pubmed	Human RAD18 interacts with ubiquitylated chromatin components and facilitates RAD9 recruitment to DNA double strand breaks.	UBE2A UBE2B	4.98e-05	6	64	2	21858012
Pubmed	Activation of ATP-binding cassette transporter A1 transcription by chromatin remodeling complex.	SMARCA2 NCOA1	4.98e-05	6	64	2	15774904
Pubmed	Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems.	UBE2A UBE2B	4.98e-05	6	64	2	17462990
Pubmed	Cooperation of HECT-domain ubiquitin ligase hHYD and DNA topoisomerase II-binding protein for DNA damage response.	UBE2A UBE2B	6.96e-05	7	64	2	11714696
Pubmed	Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins.	UBE2A UBE2B	6.96e-05	7	64	2	21816346
Pubmed	Silencing of unpaired chromatin and histone H2A ubiquitination in mammalian meiosis.	UBE2A UBE2B	6.96e-05	7	64	2	15657431
Pubmed	Cellular energy depletion resets whole-body energy by promoting coactivator-mediated dietary fuel absorption.	ABCB11 NCOA1	6.96e-05	7	64	2	21195347
Pubmed	A new mutation Rim3 resembling Re(den) is mapped close to retinoic acid receptor alpha (Rara) gene on mouse chromosome 11.	NCOA1 GSDMA	6.96e-05	7	64	2	9434940
Pubmed	Nucleosomal H2B ubiquitylation with purified factors.	UBE2A UBE2B	9.27e-05	8	64	2	21443952
Pubmed	Neuregulin repellent signaling via ErbB4 restricts GABAergic interneurons to migratory paths from ganglionic eminence to cortical destinations.	RELN EGFR	9.27e-05	8	64	2	22376909
Pubmed	Regulation of Connexin32 by ephrin receptors and T-cell protein-tyrosine phosphatase.	EGFR EPHA1	9.27e-05	8	64	2	30401746
Pubmed	En bloc transfer of polyubiquitin chains to PCNA in vitro is mediated by two different human E2-E3 pairs.	UBE2A UBE2V2	9.27e-05	8	64	2	22904075
Pubmed	The bZIP repressor proteins, c-Jun dimerization protein 2 and activating transcription factor 3, recruit multiple HDAC members to the ATF3 promoter.	HDAC6 HDAC10	1.19e-04	9	64	2	22989952
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	TRHDE EGFR TRPM3 GLUL ALDH7A1 EPHA1	1.24e-04	420	64	6	28065597
Pubmed	Wnt signaling mutants have decreased dentate granule cell production and radial glial scaffolding abnormalities.	RELN EPHA1	1.49e-04	10	64	2	14715945
Pubmed	Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A.	UBE2A UBE2B	1.49e-04	10	64	2	37633270
Pubmed	Histone Deacetylase 1 Is Essential for Rod Photoreceptor Differentiation by Regulating Acetylation at Histone H3 Lysine 9 and Histone H4 Lysine 12 in the Mouse Retina.	HDAC6 HDAC10	1.49e-04	10	64	2	28028172
Pubmed	Knockout mouse model and gametogenic failure.	UBE2A UBE2B	1.49e-04	10	64	2	9922113
Pubmed	A forward genetic screen in mice identifies mutants with abnormal cortical patterning.	RELN LRP2	1.81e-04	11	64	2	23968836
Pubmed	Diacylglycerol kinase delta regulates protein kinase C and epidermal growth factor receptor signaling.	EGFR DGKG	1.81e-04	11	64	2	17021016
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	HDAC6 SMARCA2 INO80 HDAC10	2.06e-04	157	64	4	30186101
Pubmed	Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human.	OR13C5 OR13C2	2.17e-04	12	64	2	12906860
Pubmed	Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by Reelin signaling mutant mice.	RELN GLUL	2.17e-04	12	64	2	23828756
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	EGFR SMARCA2 RNF213 GSDMA ALDH7A1	2.47e-04	304	64	5	32235678
Pubmed	Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor.	RELN GLUL	2.57e-04	13	64	2	25285789
Pubmed	Multifaceted actions of Zeb2 in postnatal neurogenesis from the ventricular-subventricular zone to the olfactory bulb.	RELN EGFR	2.57e-04	13	64	2	32253238
Pubmed	Histone deacetylase expression patterns in developing murine optic nerve.	HDAC6 HDAC10	2.99e-04	14	64	2	25011550
Pubmed	Localization of sequences related to the human RAD6 DNA repair gene on mouse chromosomes 11 and 13.	UBE2B EGFR	2.99e-04	14	64	2	7613042
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	TINAGL1 RELN COL12A1 COL6A6	3.11e-04	175	64	4	28071719
Pubmed	Ubc13-Mms2 cooperates with a family of RING E3 proteins in budding yeast membrane protein sorting.	UBE2B UBE2V2	3.45e-04	15	64	2	32265276
Pubmed	A fluorescent perilipin 2 knock-in mouse model reveals a high abundance of lipid droplets in the developing and adult brain.	EGFR GLUL	3.45e-04	15	64	2	38942786
Pubmed	Identification and characterization of microRNAs expressed in the mouse eye.	TRPM3 GLUL	3.93e-04	16	64	2	17251443
Pubmed	Brg1-dependent chromatin remodelling is not essentially required during oligodendroglial differentiation.	GLUL SMARCA2	3.93e-04	16	64	2	25568100
Pubmed	Functional genomics identifies a mechanism for estrogen activation of the retinoic acid receptor alpha1 gene in breast cancer cells.	HDAC6 NCOA1	3.93e-04	16	64	2	15831516
Pubmed	Functional interaction of ubiquitin ligase RNF167 with UBE2D1 and UBE2N promotes ubiquitination of AMPA receptor.	UBE2A UBE2B	4.45e-04	17	64	2	33650289
Pubmed	Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid-liquid phase separation-based method.	UBE2A UBE2B	4.45e-04	17	64	2	36563856
Pubmed	Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.	SMARCA2 NCOA1	4.45e-04	17	64	2	19183483
Pubmed	Interaction network of human early embryonic transcription factors.	ZNF536 WIZ SMARCA2 NCOA1 INO80	4.76e-04	351	64	5	38297188
Pubmed	Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6.	HDAC6 EGFR UBE2V2	4.92e-04	83	64	3	20029029
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	ZNF536 WIZ SMARCA2	4.92e-04	83	64	3	28794006
Pubmed	HDAC family: What are the cancer relevant targets?	HDAC6 HDAC10	5.00e-04	18	64	2	18824292
Pubmed	Ablation of BAF170 in Developing and Postnatal Dentate Gyrus Affects Neural Stem Cell Proliferation, Differentiation, and Learning.	GLUL SMARCA2	5.00e-04	18	64	2	27392482
Pubmed	RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells.	UBE2A UBE2B	5.00e-04	18	64	2	19410543
Pubmed	Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase.	EGFR NCOA1	5.59e-04	19	64	2	28424251
Pubmed	Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity.	UBE2A UBE2B	5.59e-04	19	64	2	27425610
Pubmed	Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.	WIZ SALL4	5.59e-04	19	64	2	30385546
Pubmed	Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels.	NEBL ABCB11	6.84e-04	21	64	2	23747249
Pubmed	Characterization of 458 single nucleotide polymorphisms of disease candidate genes in the Korean population.	EGFR LRP2	7.52e-04	22	64	2	12768436
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RELN EHBP1L1 HDAC6 WIZ CLASP1 VWA8 INO80 NDUFS2	8.09e-04	1082	64	8	38697112
Pubmed	Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells.	SMARCA2 SALL4	8.96e-04	24	64	2	18454139
Pubmed	Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity.	UBE2A UBE2B	8.96e-04	24	64	2	24647965
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TINAGL1 EHBP1L1 LRFN1 WIZ VWA8 INO80 FUT1 DYSF	9.27e-04	1105	64	8	35748872
Pubmed	Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.	EGFR EPHA1	9.73e-04	25	64	2	15254900
Pubmed	Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging.	UBE2A UBE2B	9.73e-04	25	64	2	17597759
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF536 HDAC6 WIZ VWA8 SMARCA2 LRP2 RNF213 INO80	9.88e-04	1116	64	8	31753913
Pubmed	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.	UBE2A UBE2B	1.05e-03	26	64	2	20061386
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	TINAGL1 HDAC6 EGFR VWA8 GLUL RNF213 CPD PLBD2 NDUFS2	1.30e-03	1451	64	9	30550785
Interaction	CD59 interactions	TINAGL1 UBE2A HDAC6 EGFR SIK2	7.96e-06	92	60	5	int:CD59
Interaction	EGR2 interactions	ZNF536 WIZ SMARCA2 NCOA1 INO80 NDUFS2	1.17e-05	171	60	6	int:EGR2
GeneFamily	Protein phosphatase 1 regulatory subunits\|Histone deacetylases, class IIB	HDAC6 HDAC10	6.33e-06	2	46	2	993
GeneFamily	Ubiquitin conjugating enzymes E2	UBE2A UBE2B UBE2V2	1.54e-04	41	46	3	102
GeneFamily	Fibronectin type III domain containing	LRFN1 COL12A1 ANKFN1 EPHA1	7.22e-04	160	46	4	555
GeneFamily	Olfactory receptors, family 13	OR13C5 OR13C2	1.55e-03	23	46	2	162
GeneFamily	Collagens	COL12A1 COL6A6	6.10e-03	46	46	2	490
CoexpressionAtlas	kidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_100	TINAGL1 RELN COL12A1 LRP2 ENPEP	5.11e-06	87	61	5	gudmap_kidney_P0_JuxtaGlom_Ren1_100
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE RELN COL12A1 DNAH10 TRPM3 LRP2 SALL4	8.71e-09	184	64	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE RELN COL12A1 DNAH10 TRPM3 LRP2 SALL4	8.71e-09	184	64	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE RELN COL12A1 DNAH10 TRPM3 LRP2 SALL4	8.71e-09	184	64	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 RELN COL12A1 SLC24A4 EGFR SYTL4	2.33e-07	180	64	6	c6030e725e3d86d5d74a1676330c77ffeceb324f
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-G\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	NEBL COL6A6 CES1 ENPEP EPHA1 SPX	3.96e-07	197	64	6	a21a710c824f9e5c7ef1674168d1ce5aef85bd35
ToppCell	343B-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NEBL COL6A6 CES1 GLUL ENPEP EPHA1	4.20e-07	199	64	6	212e89d097753790061310373a1fafba773488b6
ToppCell	343B-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NEBL COL6A6 CES1 GLUL ENPEP EPHA1	4.20e-07	199	64	6	14b676aa289c0578a37be32cec3ea285c79d97cc
ToppCell	TCGA-Kidney\|World / Sample_Type by Project: Shred V9	TRHDE TRPM3 LRP2 ENPEP SPX	2.59e-06	151	64	5	e31974c0d0a0c644205a0ee6013ab74a09d8a306
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE COL12A1 EGFR LRP2 SPX	3.88e-06	164	64	5	382e42701779d12a7948690b3be72d06dd75c8b4
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CLASP1 SIK2 TOP6BL PLBD2 PNPO	5.18e-06	174	64	5	a1f745962a104c6f4b86b7e482da8755384c773a
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TINAGL1 ERFE COL12A1 DGKG ENPEP	5.18e-06	174	64	5	015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCA5 RELN DNAH10 GSDMA DYSF	5.32e-06	175	64	5	0801cccec6915aefc135262fc74580280fd51aa5
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCA5 RELN DNAH10 GSDMA DYSF	5.32e-06	175	64	5	09163e7030f76d706eccabdb1d5ec45f8412aa75
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 RELN COL12A1 EGFR SYTL4	5.94e-06	179	64	5	01302505816f272243659e20d751b61a198a2fc0
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 RELN EGFR PEG10 ANKFN1	6.11e-06	180	64	5	b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 RELN SLC24A4 EGFR ABCB11	6.27e-06	181	64	5	062f00736eed96e4f4327615d093558dd7d82b20
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 RELN COL12A1 EGFR ANKFN1	6.97e-06	185	64	5	487fa382232564f075960899d50afa0edae5d258
ToppCell	21-Trachea-Epithelial-Intermediate_ciliated\|Trachea / Age, Tissue, Lineage and Cell class	DNAH10 CES1 CFAP70 CFAP161 ANKFN1	7.35e-06	187	64	5	1a2178a195d078d1963947b327c6d0d4f2f48341
ToppCell	Mesenchymal-vascular_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	TINAGL1 COL12A1 DGKG ENPEP KCNT1	8.14e-06	191	64	5	fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TINAGL1 RELN COL12A1 COL6A6 ENPEP	8.56e-06	193	64	5	cd45118ced91b10baed3b1068d4673ec99824b86
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE NEBL TRPM3 LRP2 ENPEP	8.56e-06	193	64	5	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	368C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NEBL CES1 ENPEP EPHA1 SPX	8.78e-06	194	64	5	d9eec28fa7b255c0ec023276dd955f1e276e7159
ToppCell	368C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NEBL CES1 ENPEP EPHA1 SPX	8.78e-06	194	64	5	e4d7e9709ce42d4610e44d3445927eefbcbb9eff
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M\|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.	TRPM3 GLUL LRP2 SALL4 ALDH7A1	9.23e-06	196	64	5	1e9ccbd5be7839a74108f0cd07a6d2d736bc7f1b
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|lung / Disease (COVID-19 only), tissue and cell type	EHBP1L1 SLC24A4 GLUL RNF213 DYSF	9.46e-06	197	64	5	a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EHBP1L1 SLC24A4 GLUL RNF213 DYSF	9.69e-06	198	64	5	ea34096bee852a7e996f097fa279381afa8f86ff
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL12A1 COL6A6 PEG10 SMARCA2 ENPEP	9.93e-06	199	64	5	9846d6a31635fde759d55674631c11ab9270a603
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN COL12A1 COL6A6 PEG10 ENPEP	9.93e-06	199	64	5	83383d9ae4f501754fd3da0215ce6f0e3c70562c
ToppCell	Tracheal-NucSeq-Stromal-Schwann-Schwann_Myelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF536 RELN TRPM3 PEG10 SALL4	9.93e-06	199	64	5	4e4bdcd2e8b518156d5ebd294804180acaa3566b
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-BAGE2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ZNF536 RELN EGFR PEG10 ANKFN1	1.02e-05	200	64	5	26f07d271e984f375145e4c10528fba44a5811e1
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-BAGE2-L1-2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ZNF536 RELN EGFR PEG10 ANKFN1	1.02e-05	200	64	5	c3637827ceba16b0d7956c280dd2ddbc8b1ba55e
ToppCell	Tracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TINAGL1 PSTK COL12A1 DGKG PLCD1	1.02e-05	200	64	5	410b1a31de21c57d87ca2104f61cf4a7d4dd2f30
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-CHRNA4-L1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ZNF536 RELN COL12A1 EGFR ANKFN1	1.02e-05	200	64	5	e2ced6eb1de9a526c34c7558b9c637854916e624
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-CHRNA4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ZNF536 RELN COL12A1 EGFR ANKFN1	1.02e-05	200	64	5	9bc924755e5a4c464408e6103b86bf1b4e8c58b5
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Vip_Nptx2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RELN TRPM3 PEG10 SPX	2.88e-05	122	64	4	91e338db581b36baffecc323b1909f2069b27242
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Intermediate_Fibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ERFE DNAH10 SIK2 EPHA1	4.54e-05	137	64	4	dd5364a1002650d21e0c83d8c701b5f7b09d1c19
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLC5A5 TRHDE RELN COL6A6	5.51e-05	144	64	4	71107275767a0728541a3695715c44874b3e5efc
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLC5A5 TRHDE RELN DGKG	5.97e-05	147	64	4	50e86860a94be103092c40e39a172eac92372f0d
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZNF536 RELN EGFR PEG10	6.13e-05	148	64	4	5e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCell	frontal_cortex\|World / Per Region, Lineage, Cell class, Cell type, Cell subtype	COL12A1 DNAH10 DYSF SPX	6.80e-05	152	64	4	f9c29d4568402ca07a717dbffb3ccc7f35c5fe56
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC24A4 DNAH10 CFAP161 ANKFN1	7.15e-05	154	64	4	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC24A4 DNAH10 CFAP161 ANKFN1	7.15e-05	154	64	4	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ZNF536 RELN EGFR PEG10	7.33e-05	155	64	4	105d59d8a1bb8cb37eef2c1767d737b2108ac7c5
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE COL12A1 DNAH10 LRP2	8.29e-05	160	64	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE COL12A1 DNAH10 LRP2	8.29e-05	160	64	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Otof-Lmo2_(eccentric_SPN,_dSPN-like_markers)-\|Striatum / BrainAtlas - Mouse McCarroll V32	SLC46A2 ADAM21 ANKFN1	8.43e-05	59	64	3	dbb61f03be7d2c7fa7d32c743fcff2dc91ae0d75
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Otof-Lmo2_(eccentric_SPN,_dSPN-like_markers)\|Striatum / BrainAtlas - Mouse McCarroll V32	SLC46A2 ADAM21 ANKFN1	8.43e-05	59	64	3	e6cbbe1a4961066cae8f8c03a838f37e60a5391a
ToppCell	343B-Epithelial_cells-Epithelial-H_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TINAGL1 RELN COL6A6 SPX	8.49e-05	161	64	4	da9eecf919866a9c579d7a707a996cf335213134
ToppCell	343B-Epithelial_cells-Epithelial-H_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TINAGL1 RELN COL6A6 SPX	8.49e-05	161	64	4	d431625c32f59a6b552191f3adc5198bd16ad5cf
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLC5A5 TRHDE RELN DGKG	8.49e-05	161	64	4	dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SLC5A5 TINAGL1 DGKG KCNT1	8.91e-05	163	64	4	51dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF536 RELN SLC24A4 DGKG	9.56e-05	166	64	4	f742d15b02a6f651bbd00f53e3d871f40d05a03d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF536 RELN SLC24A4 DGKG	9.56e-05	166	64	4	0f013bb5fdb72e88c2fc73d60cd01551a2db6341
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF536 RELN SLC24A4 DGKG	9.56e-05	166	64	4	e941df9a1091164edde3def8fc7d410186b2bd88
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF536 RELN SLC24A4 DGKG	9.56e-05	166	64	4	aeda46bea5d8463c24a83b98b9ed92d962d733e5
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ZNF536 TRPM3 LRP2 SPX	1.00e-04	168	64	4	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLC5A5 TRHDE RELN DGKG	1.05e-04	170	64	4	8ab67e2b6e30fdf9e9a2c02e31d4df34e751a3ed
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T\|bone_marrow / Manually curated celltypes from each tissue	TRHDE LCA5 DGKG FUT1	1.10e-04	172	64	4	a66402d15853f0c9e3d06394ff9ac08d1da128ff
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 RELN EGFR PEG10	1.12e-04	173	64	4	0ba64e5385fe714f876002520f8b5202809bf11e
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN SLC24A4 TRPM3 SYTL4	1.12e-04	173	64	4	922356a5b4c84607318ac24d7caa2e235b72b066
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	DNAH10 CFAP70 CFAP161 ANKFN1	1.15e-04	174	64	4	f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 COL12A1 EGFR SYTL4	1.17e-04	175	64	4	e78bf0c33a741bb97e987e41ac33da9e623a08ec
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LCA5 HDAC6 PEG10 DYSF	1.17e-04	175	64	4	a5db428b078938627e61b7e944c1e0c1d61ac2da
ToppCell	BAL-Control-cDC_11\|Control / Compartment, Disease Groups and Clusters	SLC24A4 TRPM3 CES1 PLCD1	1.17e-04	175	64	4	daf014e15a354956e9149c83fd89d0af0d07eb00
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	DNAH10 CFAP70 CFAP161 ANKFN1	1.17e-04	175	64	4	c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LCA5 HDAC6 PEG10 DYSF	1.17e-04	175	64	4	8b498eea1ec1c1f27b171025c3d08adf3687bafc
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	SIK2 TOP6BL PLBD2 PNPO	1.17e-04	175	64	4	78a86cac3e6c0d115c997d1c29ee0e24af54551f
ToppCell	facs-Aorta\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 LRP2 DYSF ENPEP	1.20e-04	176	64	4	0b3491451be02c18a16cdb875645be47eb867a7f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 RELN SLC24A4 EGFR	1.22e-04	177	64	4	84116796ca4c7007508c0f1a68a1135c7b922278
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NEBL COL6A6 PEG10 ENPEP	1.22e-04	177	64	4	7af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 LRP2 CFAP70 CFAP161	1.25e-04	178	64	4	58857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCell	droplet-Spleen-nan-24m-Hematologic-erythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TINAGL1 UBE2B GLUL PNPO	1.25e-04	178	64	4	9c4950357087212b2388116ba8866c359628694d
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE SLC24A4 DNAH10 CFAP161	1.25e-04	178	64	4	b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE NEBL EGFR SPX	1.25e-04	178	64	4	c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NAT1 DNAH10 CFAP70 ANKFN1	1.25e-04	178	64	4	de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 LRP2 CFAP70 CFAP161	1.25e-04	178	64	4	8b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCell	PBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_3\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	VWA8 SYTL4 CFAP161 SPX	1.25e-04	178	64	4	850fcd368c4478c57eaedc74544773ea220f41f3
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 LRP2 CFAP70 CFAP161	1.25e-04	178	64	4	b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE SLC24A4 DNAH10 CFAP161	1.25e-04	178	64	4	579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCell	PBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_3\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	VWA8 SYTL4 CFAP161 SPX	1.25e-04	178	64	4	a16857da9f2907c176213a326112a1b4cbd0e628
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 RELN COL12A1 EGFR	1.28e-04	179	64	4	cd7f0e8f4abb2a2bac366c8910c8c5fda841dbce
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NAT1 TRPM3 LRP2 ENPEP	1.28e-04	179	64	4	d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 RELN EGFR ENPEP	1.28e-04	179	64	4	c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRPM3 LRP2 ENPEP SPX	1.31e-04	180	64	4	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	facs-GAT-Fat-3m-Epithelial-epithelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 CFAP70 CFAP161 ANKFN1	1.33e-04	181	64	4	e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCell	facs-GAT-Fat-3m-Epithelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 CFAP70 CFAP161 ANKFN1	1.33e-04	181	64	4	11cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE NEBL EGFR SPX	1.33e-04	181	64	4	071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE EGFR LRP2 SPX	1.33e-04	181	64	4	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NAT1 DNAH10 CFAP70 ANKFN1	1.33e-04	181	64	4	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	facs-GAT-Fat-3m-Epithelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 CFAP70 CFAP161 ANKFN1	1.33e-04	181	64	4	5ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	NAT1 DNAH10 CFAP70 ANKFN1	1.36e-04	182	64	4	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	ASK454-Epithelial\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	TINAGL1 COL12A1 NEBL SYTL4	1.36e-04	182	64	4	ab15316cff989b61ff397a866d7ca8b49c13e981
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 RELN SLC24A4 EGFR	1.36e-04	182	64	4	d3a037268f026eb2f84428b1821022503cef7756
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TINAGL1 ZNF536 TRPM3 SPX	1.36e-04	182	64	4	d4cb23b5a974c096a0ce84b47fe351eef44894d7
ToppCell	COPD-Epithelial-ATI\|World / Disease state, Lineage and Cell class	COL12A1 NEBL EGFR PEG10	1.36e-04	182	64	4	e95d946a43b1579af199900bb0e3eacbb9d65300
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRHDE TRPM3 LRP2 SPX	1.36e-04	182	64	4	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE NEBL EGFR SPX	1.39e-04	183	64	4	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC6 TRPM3 LRP2 ENPEP	1.39e-04	183	64	4	facd6dbe0851b537d70a899ac7485714ab27d071
ToppCell	10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Megakaryocyte_early\|bone_marrow / Manually curated celltypes from each tissue	SYTL4 DGKG CFAP161 SPX	1.39e-04	183	64	4	3cc9f3dc3bc4bde1d3408b0a6ba58e135a11036d
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRHDE TRPM3 LRP2 ENPEP	1.39e-04	183	64	4	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
Computational	Genes in the cancer module 4.	UBE2A UBE2B UBE2V2	2.27e-05	21	29	3	MODULE_4
Computational	Genes in the cancer module 82.	UBE2A UBE2B UBE2V2	3.44e-05	24	29	3	MODULE_82
Drug	3,2'-dimethyl-4-aminobiphenyl	NAT1 DYSF ENPEP	8.55e-06	15	62	3	CID000025948
Drug	[(4E)-4-[(2,2-difluoroethylamino)methylene]-6-methyl-5-oxo-3-pyridyl]methyl dihydrogen phosphate	SLC5A5 ABCB11 ALDH7A1	1.27e-05	17	62	3	CID011840958
Drug	Lomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; PC3; HT_HG-U133A	TINAGL1 NEBL VWA8 GLUL SMARCA2 ALDH7A1	1.60e-05	197	62	6	3723_DN
Drug	NS-398; Down 200; 10uM; MCF7; HT_HG-U133A	EHBP1L1 HDAC6 CPD PLCD1 ENPEP EPHA1	1.60e-05	197	62	6	6897_DN
Drug	Scopolamin-N-oxide hydrobromide [6106-81-6]; Down 200; 10uM; MCF7; HT_HG-U133A	SLC5A5 EHBP1L1 WIZ EGFR PLCD1 TOP6BL	1.60e-05	197	62	6	2262_DN
Drug	Bethanechol chloride [590-63-6]; Down 200; 20.4uM; MCF7; HT_HG-U133A	HDAC6 WIZ NEBL EGFR NCOA1 ENPEP	1.69e-05	199	62	6	5539_DN
Drug	5,8,11,14-Eicosatetraynoic Acid	SLC5A5 EGFR CES1	1.81e-05	19	62	3	ctd:D015117
Drug	PCI-24781	HDAC6 HDAC10	2.18e-05	3	62	2	CID011749858
Disease	schizophrenia (is_marker_for)	RELN EGFR GLUL	1.21e-04	44	64	3	DOID:5419 (is_marker_for)
Disease	N-acetylputrescine measurement	NAT1 HDAC10	3.01e-04	12	64	2	EFO_0800127
Disease	congenital heart disease (implicated_via_orthology)	UBE2A UBE2B LRP2	4.60e-04	69	64	3	DOID:1682 (implicated_via_orthology)
Disease	syndromic intellectual disability (implicated_via_orthology)	UBE2A UBE2B	5.45e-04	16	64	2	DOID:0050888 (implicated_via_orthology)
Disease	Tourette syndrome, schizophrenia	ZNF536 DNAH10	6.93e-04	18	64	2	EFO_0004895, MONDO_0005090
Disease	temporal lobe epilepsy (is_marker_for)	RELN GLUL	8.58e-04	20	64	2	DOID:3328 (is_marker_for)
Disease	obesity (implicated_via_orthology)	HDAC6 DNAH10 GLUL NCOA1	1.24e-03	215	64	4	DOID:9970 (implicated_via_orthology)
Disease	Intrahepatic Cholangiocarcinoma	SLC5A5 EGFR	1.24e-03	24	64	2	C0345905
Disease	Extrahepatic Cholangiocarcinoma	SLC5A5 EGFR	1.24e-03	24	64	2	C3805278
Disease	response to venlafaxine	COL12A1 DYSF	1.35e-03	25	64	2	EFO_0006328
Disease	Cholangiocarcinoma	SLC5A5 EGFR	1.46e-03	26	64	2	C0206698
Disease	Myopia	TRHDE TRPM3 TOP6BL DYSF ALDH7A1	1.49e-03	385	64	5	HP_0000545
Disease	Malignant mesothelioma	COL12A1 EGFR SMARCA2	1.73e-03	109	64	3	C0345967
Disease	Child Development Disorders, Specific	LRP2 KCNT1	1.81e-03	29	64	2	C0085997
Disease	Child Development Deviations	LRP2 KCNT1	1.81e-03	29	64	2	C0085996
Disease	Developmental Disabilities	LRP2 KCNT1	1.94e-03	30	64	2	C0008073
Disease	ocular sarcoidosis	EGFR LRP2 CFAP161	2.07e-03	116	64	3	EFO_0010723

Protein segments in the cluster

Peptide	Gene	Start	Entry
WTLQMGYPVITILGN	TRHDE	591	Q9UKU6
GRSYQMWQPLELISG	NAT1	126	P18440
YMVGINKQEFGWLIP	CES1	346	P23141
WSEQQQILNGTPLYM	EPHA1	51	P21709
FPVAVYGWNNAIAMI	ALDH7A1	196	P49419
IGIEIWNQGNVFPMT	ADAM21	256	Q9UKJ8
LSGLEVQRSGPQYMW	GSDMA	406	Q96QA5
EWPYMLVGSVGAAVN	ABCB11	751	O95342
MAQNVYGPGVRIGNW	CFAP161	1	Q6P656
VPWGLQTMVVNYGST	SLC24A4	536	Q8NFF2
MNWLANLYEQGINGI	INO80	526	Q9ULG1
QEGYPMQIEQFWKGL	MMP24	411	Q9Y5R2
NPVGVGRYLNTWLME	LEXM	351	Q3ZCV2
YNNLEALPWEAVGQM	LRFN1	171	Q9P244
QEGQESPEQWQRMYG	KCNT1	521	Q5JUK3
YNVTAMNVPIAVWNG	LIPF	326	P07098
NGVLYLQMGQWTSVF	ERFE	316	Q4G0M1
GIQNPYRGTVVWMVP	EHBP1L1	61	Q8N3D4
GQGRSLYVPVMITWN	PEG10	661	Q86TG7
WETGRYQLGMYPIQN	LCA5	436	Q86VQ0
QSVVMYNIQWPLGIV	LRP2	1676	P98164
DTWTRQMGYPVLNVN	ENPEP	536	Q07075
LYPQVMEFWQGQTNR	PNPO	211	Q9NVS9
YVPMAAGSWIIGAVN	OR13C5	141	Q8NGS8
YVPMAAGSWIIGAVN	OR13C2	141	Q8NGS9
VEWAQQFGGAVMYPS	NDUFS2	41	O75306
GPILGNMWAIDNVYI	RELN	656	P78509
NYSPVEMWNGGCQIV	PLCD1	561	P51178
YAMNWVRQAPGQGLE	IGHV7-4-1	51	A0A0J9YVY3
AILNIPSMYGGTNLW	DGKG	656	P49619
PAGVMGENNTLVWKY	EGFR	596	P00533
LPWNQVGMGNADYVA	HDAC10	226	Q969S8
NIYDVGPTTMHVQWQ	COL12A1	1481	Q99715
AQMDYLNPNVWGLKG	CFAP70	956	Q5T0N1
NVPGGMQDWNYLQTN	CPD	741	O75976
MPSYAQLVQRGWGSA	CERS1	16	P27544
QGYTINVPWNQVGMR	HDAC6	301	Q9UBN7
NVPWNQVGMRDADYI	HDAC6	306	Q9UBN7
QGMGPAKESVWQYFV	DNAH10	2906	Q8IVF4
PVVWNQYTSMLNGGL	SALL4	966	Q9UJQ4
NQTRLPGGQWIYMSD	DYSF	956	O75923
QTLLEGQPWMETYLQ	COL6A6	1201	A6NMZ7
WTVYPNGRFGNQMGQ	FUT1	81	P19526
PQGEKVQAMYIWIDG	GLUL	21	P15104
MRQYPGSWAEGTLQL	SYTL4	646	Q96C24
NWTPQAMLYLKGAQG	SPX	36	Q9BT56
MIKAINQGNYGWQAG	TINAGL1	146	Q9GZM7
GLEWMVSLYNNNLNG	SMARCA2	731	P51531
AFPVQQMEIWGVYTL	TOP6BL	336	Q8N6T0
GYQSPDMKAWQQGAI	NCOA1	1276	Q15788
QQYEGPQLDIWSMGV	SIK2	191	Q9H0K1
LRQMGVTEWYVNGSP	WIZ	1066	O95785
QVSAYNMKGWGPAQT	ANKFN1	346	Q8N957
QAANPQYVWDRMLGG	CLASP1	121	Q7Z460
PMIYEGQAQLWTDLQ	RNF213	566	Q63HN8
GTLVWLSMYGVNQAQ	SLC5A5	251	Q92911
IYGQQWPVGSLEQAM	TRPM3	501	Q9HCF6
QGWAIGVVAYDDVMP	PSTK	46	Q8IV42
NNIMVWNAVIFGPEG	UBE2A	31	P49459
GYSVVMAGRNVWQPT	nan	651	Q3C1V9
DPVNSYQAWQLMARG	ZNF536	516	O15090
WTGMIIGPPRTNYEN	UBE2V2	46	Q15819
EPLGWNQVQVGYGMA	SLC46A2	311	Q9BY10
NQWMIVDYKAFIPGG	PLBD2	376	Q8NHP8
TLPEQTFMGYWTIGQ	VWA8	1041	A3KMH1
NNIMQWNAVIFGPEG	UBE2B	31	P63146
IVNVQPIDDGWMYGT	NEBL	981	O76041