Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone binding

PHF8 SRCAP TSPYL4 TONSL

1.03e-03265344GO:0042393
DomainTGFb_propeptide

BMP6 GDF6

1.11e-0328332PF00688
DomainTGF-b_N

BMP6 GDF6

1.11e-0328332IPR001111
DomainTGF-beta-rel

BMP6 GDF6

1.45e-0332332IPR015615
DomainTGFb_CS

BMP6 GDF6

1.45e-0332332IPR017948
DomainTGFB

BMP6 GDF6

1.94e-0337332SM00204
DomainTGF_BETA_2

BMP6 GDF6

1.94e-0337332PS51362
DomainTGF_beta

BMP6 GDF6

1.94e-0337332PF00019
DomainTGF-b_C

BMP6 GDF6

1.94e-0337332IPR001839
DomainTGF_BETA_1

BMP6 GDF6

1.94e-0337332PS00250
DomainLRR_6

CARMIL3 TONSL

4.24e-0355332PF13516
Domain-

BMP6 GDF6

6.23e-03673322.10.90.10
DomainCystine-knot_cytokine

BMP6 GDF6

6.23e-0367332IPR029034
DomainHelicase_C

SRCAP DHX40

1.53e-02107332PF00271
DomainHELICc

SRCAP DHX40

1.53e-02107332SM00490
DomainHelicase_C

SRCAP DHX40

1.56e-02108332IPR001650
DomainHELICASE_CTER

SRCAP DHX40

1.58e-02109332PS51194
DomainHELICASE_ATP_BIND_1

SRCAP DHX40

1.58e-02109332PS51192
DomainDEXDc

SRCAP DHX40

1.58e-02109332SM00487
DomainHelicase_ATP-bd

SRCAP DHX40

1.61e-02110332IPR014001
DomainSH2

CBLB INPP5D

1.61e-02110332SM00252
DomainSH2

CBLB INPP5D

1.64e-02111332PS50001
DomainSH2

CBLB INPP5D

1.67e-02112332IPR000980
Domain-

CBLB INPP5D

1.67e-021123323.30.505.10
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

PHF8 SRCAP G3BP1 POM121C HCFC1 DHX40

9.07e-0734134632971831
Pubmed

Dampening of death pathways by schnurri-2 is essential for T-cell development.

HIVEP2 BCL2L11

2.78e-06334221475200
Pubmed

PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression.

PHF8 HCFC1

1.39e-05634220622854
Pubmed

Neuronal differentiation of precursors in the neocortical ventricular zone is triggered by BMP.

BMP6 GDF6

1.94e-0573429786991
Pubmed

miR-155 Controls Lymphoproliferation in LAT Mutant Mice by Restraining T-Cell Apoptosis via SHIP-1/mTOR and PAK1/FOXO3/BIM Pathways.

BCL2L11 INPP5D

1.94e-05734226121028
Pubmed

CIN85 interacting proteins in B cells-specific role for SHIP-1.

CBLB INPP5D SHKBP1

2.05e-055434321725061
Pubmed

The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow.

BCL2L11 INPP5D

3.33e-05934221423172
Pubmed

The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation in Cooperation with Phosphatase PTPN22 and Dok Adaptors.

CBLB INPP5D

3.33e-05934227926878
Pubmed

Neuronal patterning by BMPs: a requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord.

BMP6 GDF6

6.08e-05123429808626
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

AKNA RIPOR1 HIVEP2 SRCAP BCL2L11 POM121C HCFC1

8.14e-05110534735748872
Pubmed

Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics.

CBLB INPP5D

1.74e-042034231591574
Pubmed

The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression.

BMP6 CBLB INPP5D

2.16e-0411934324162774
Pubmed

Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.

HIVEP2 BCL2L11 HCFC1

2.68e-0412834325332235
Pubmed

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

PHF8 HCFC1 MAML3

2.74e-0412934323022380
Pubmed

Voltage-gated ion channel Kv4.3 is associated with Rap guanine nucleotide exchange factors and regulates angiotensin receptor type 1 signaling to small G-protein Rap.

G3BP1 NDUFS2

3.21e-042734217725712
Pubmed

Deep sequencing and proteomic analysis of the microRNA-induced silencing complex in human red blood cells.

G3BP1 INPP5D

3.70e-042934225681748
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

HIVEP2 G3BP1 HCFC1 NDUFS2 DHX40 SHKBP1

3.86e-04100534619615732
Pubmed

Human transcription factor protein interaction networks.

SSBP2 PHF8 SRCAP G3BP1 POM121C HCFC1 DHX40

3.95e-04142934735140242
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

SRCAP HCFC1 TONSL

4.27e-0415034328242625
Pubmed

Tandem immunoprecipitation of phosphotyrosine-mass spectrometry (TIPY-MS) indicates C19ORF19 becomes tyrosine-phosphorylated and associated with activated epidermal growth factor receptor.

CBLB HCFC1

4.81e-043334218271526
Pubmed

Gene content of the 750-kb critical region for mouse embryonic ectoderm lethal tcl-w5.

PHF8 MYO1F

5.72e-043634215112104
CoexpressionGSE6674_ANTI_IGM_VS_CPG_STIM_BCELL_UP

BCL2L11 CBLB CCDC28B DHX40 ZC3H12D

5.72e-06200345M6927
CoexpressionGSE8515_IL1_VS_IL6_4H_STIM_MAC_DN

SNAPC2 SRCAP CDK5R2 TONSL

1.13e-04194344M5767
CoexpressionGSE28130_ACTIVATED_VS_INDUCEED_TREG_UP

BCL2L11 HCFC1 MAML3 ADCY8

1.20e-04197344M8343
CoexpressionGSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_UP

ITGA7 INPP5D IPMK MYO1F

1.28e-04200344M8955
CoexpressionGSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_DN

CBLB CCDC28B TSPYL4 DHX40

1.28e-04200344M8956
CoexpressionGSE7852_THYMUS_VS_FAT_TCONV_DN

AKNA HIVEP2 CBLB MYO1F

1.28e-04200344M5750
CoexpressionGSE20715_0H_VS_48H_OZONE_LUNG_UP

AKNA TSPYL4 DHX40 ADCY8

1.28e-04200344M4368
CoexpressionGSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_UP

DMRTB1 BMP6 SSBP2 CCDC28B

1.28e-04200344M3428
CoexpressionGSE6674_UNSTIM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_UP

RIPOR1 BCL2L11 DHX40 ZC3H12D

1.28e-04200344M6925
CoexpressionLAKE_ADULT_KIDNEY_C2_PODOCYTES

SSBP2 HIVEP2 CBLB MAML3

1.59e-04212344M39221
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RIPOR1 ITGA7 SRCAP POM121C TSPYL4 ADCY8

8.42e-0919934685bb28369e0568b7b3bda095722102fc793f60ef
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA CBLB INPP5D ZC3H12D MYO1F

3.29e-07191345d9506b88d806aadd4c2b9bf86fe994c47799e7f6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA CBLB INPP5D ZC3H12D MYO1F

3.29e-07191345b42c54308abe1241cc38ddce96b9d38d07983891
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA CBLB INPP5D ZC3H12D MYO1F

3.29e-071913459aabbc65430e2233b8f2d3fff9face7807b88b48
ToppCellAdult-Immune-natural_killer_cell-D122|Adult / Lineage, Cell type, age group and donor

AKNA CBLB CARMIL3 INPP5D

7.78e-06167344ff1ce3b1a2d91d2ad979f25899db4f4eeb865892
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

AKNA CBLB INPP5D MYO1F

9.15e-0617434433d6b81f31bfcb9c4b30206d88e20b9a94fba4a2
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKNA CBLB INPP5D MYO1F

9.58e-061763446b06da40eb97ea2db09f3a769494738b3e5fe3fa
ToppCellControl-T_cells-CD8+_T_cells|Control / group, cell type (main and fine annotations)

AKNA CBLB INPP5D MYO1F

1.17e-0518534402ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA CBLB INPP5D MYO1F

1.17e-0518534445890fa81c65a48f4fdec164a4c8d0e2831243c0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA CBLB INPP5D MYO1F

1.17e-05185344585bcfdff85bf43f5aa4cd1b39f7dcf1c78d7b02
ToppCellControl-T_cells-NK_cells|Control / group, cell type (main and fine annotations)

AKNA CBLB INPP5D MYO1F

1.17e-05185344755c0998c729f462399f1d5e88adf4bfae31be30
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

AKNA BCL2L11 CBLB MYO1F

1.22e-05187344d17352f769c3c66601b65d060626eecff41b0482
ToppCellControl-T_cells|Control / group, cell type (main and fine annotations)

AKNA CBLB INPP5D MYO1F

1.22e-05187344f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BMP6 LONRF3 ITGA7 MAML3

1.22e-0518734402105c82a9ba79d2f19e002188377fc3440770c2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CBLB CCDC28B INPP5D MYO1F

1.24e-05188344f7dc29dfec68236883469e848be5db34f5526d6b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CBLB CCDC28B INPP5D MYO1F

1.24e-051883445ae8ccdd328cf117da1d01ced2c3b7f763a5f1f1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CBLB CCDC28B INPP5D MYO1F

1.24e-051883449abd78970bbe4ed03b59a83da63bbd334712f605
ToppCellCOVID-19-T_cells-CD8+_T_cells|COVID-19 / group, cell type (main and fine annotations)

AKNA CBLB INPP5D MYO1F

1.27e-051893442c018d6120f65f0b2704b483bc9da1c0984872e3
ToppCellCOVID-19-T_cells-NK_cells|COVID-19 / group, cell type (main and fine annotations)

AKNA CBLB INPP5D MYO1F

1.27e-05189344b699152dfbb8cd8ed724e1e5a51838f29b681b62
ToppCellControl-T_cells-CD4+_T_cells|Control / group, cell type (main and fine annotations)

AKNA CBLB INPP5D MYO1F

1.29e-051903440733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AKNA CBLB INPP5D MYO1F

1.29e-05190344d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellCOVID-19-lung-CD8+_T_cells|COVID-19 / Disease (COVID-19 only), tissue and cell type

AKNA CBLB INPP5D MYO1F

1.32e-05191344543f8ae07cc2e6950c888115a5ca9445e3c0f618
ToppCellAdult-Immune-T_lymphocyte-D175|Adult / Lineage, Cell type, age group and donor

AKNA HIVEP2 INPP5D ZC3H12D

1.32e-051913440b84fd1dc68146d9f72422b102744d2847f5ecb2
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-NK|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

AKNA CBLB INPP5D MYO1F

1.35e-05192344a06d5d3c2537f8d2b1dc6b6f3e88a80b5c2a1850
ToppCellCOVID-19-lung-CD8+_T_cells|lung / Disease (COVID-19 only), tissue and cell type

AKNA CBLB INPP5D MYO1F

1.38e-05193344780e23e2705fc5c1b70e37568b79731ced5038bd
ToppCellCD8+_Memory_T_cell-CV-0|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

AKNA BCL2L11 CBLB MYO1F

1.38e-05193344995781d87a919c0380750878bafe584342bb83ad
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

AKNA CBLB INPP5D MYO1F

1.38e-051933441cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCell343B-Lymphocytic-NK_cells-NK_cell_C|343B / Donor, Lineage, Cell class and subclass (all cells)

AKNA CCDC28B INPP5D MYO1F

1.40e-05194344fe36cf5cf8ebd761d29ad23ee074128a12d32031
ToppCellT_cells-GZMK+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

AKNA CBLB INPP5D MYO1F

1.43e-05195344003ea7ddec6c1c98d2f6470bb51ebd97450eb936
ToppCellCOVID-19-kidney-T-cells-1|kidney / Disease (COVID-19 only), tissue and cell type

AKNA CBLB INPP5D MYO1F

1.49e-051973449bb7faf4ef63cca4d06c60e6c05a9616fdb6b98e
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

AKNA BCL2L11 CBLB INPP5D

1.49e-051973441ca06d6d288cb58a6e8062ebc01831e58ee5be4b
ToppCell343B-Lymphocytic-NK_cells-NK_cell_C|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

AKNA CCDC28B INPP5D MYO1F

1.49e-05197344879974aff3f887648a00b4659b46d9897c9eb467
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ITGA7 SRCAP POM121C TSPYL4

1.52e-05198344399760b6b6fef8639ded53b14f251b9fce600e81
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKNA INPP5D ZC3H12D MYO1F

1.58e-05200344d8459e45a8396a9ee063666a1928c649162c5727
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKNA CBLB INPP5D MYO1F

1.58e-0520034402c4169a23e5aaa0d4bfc78b51ba19ce8157dc3e
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKNA CBLB INPP5D MYO1F

1.58e-05200344be9a43acc2f926b9433ab3f018b911b03896a924
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_GZMK+|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKNA CBLB INPP5D MYO1F

1.58e-05200344510d84bf7a4621b079e5a7330d25e04508c84a49
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKNA CBLB INPP5D MYO1F

1.58e-052003449ef322486e46e4ff05a8cbe06cf8019e996c94b3
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|368C / Donor, Lineage, Cell class and subclass (all cells)

AKNA ZNF211 ZC3H12D

1.94e-0414834380470353e12599440f711b6e107730763376d04d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA INPP5D MYO1F

1.94e-0414834312fa2c4922f03803006c606b1b16e79441e3bb13
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|390C / Donor, Lineage, Cell class and subclass (all cells)

AKNA CARMIL3 MYO1F

2.01e-04150343fdbfc8f743cf848978cf0488493f6df60be53982
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

HIVEP2 CBLB ZC3H12D

2.26e-041563431545169694f686d28648a68b552c2ae606599d66
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|343B / Donor, Lineage, Cell class and subclass (all cells)

ZNF211 LONRF3 SRCAP

2.30e-041573430362c04b7b0b5017964b3a73ee678ae53e7238d7
ToppCell356C-Fibroblasts-Fibroblast-D-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

BMP6 SRCAP BCL2L11

2.39e-04159343299e2162a82e31196d7f3a110c2db622349edfff
ToppCell356C-Fibroblasts-Fibroblast-D|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

BMP6 SRCAP BCL2L11

2.39e-041593430a3a363b30a8c741e1a3e2525725108d03c21776
ToppCellSubstantia_nigra-Hematopoietic|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

AKNA INPP5D MYO1F

2.44e-0416034319d71d02f06f34eff37d268a78e5eed34da4ca44
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA INPP5D ZC3H12D

2.53e-0416234358fe827198c172eeaa26273b0fad7991a718b0bf
ToppCelldroplet-Pancreas-Endocrine-18m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA INPP5D MYO1F

2.57e-04163343aaff80d254131d1f1230bb12b6f43bc061ab5ab3
ToppCelldroplet-Pancreas-Endocrine-18m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA INPP5D MYO1F

2.57e-041633438b0f8a2d5b38f3bbff265211a7607acc85fa38b0
ToppCelldroplet-Pancreas-Endocrine-18m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA INPP5D MYO1F

2.57e-04163343644c8a8af6a378fced4c70dec9a0de906f8d6e69
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Lymphocytic-mature_NK_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA BCL2L11 TONSL

2.62e-0416434322f37c39fdce2cf6dc72c6db619537d4b0234839
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA GDF6 ZC3H12D

2.67e-0416534322293c6b55f44636440cd737efb786ff5de3373d
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA INPP5D ZC3H12D

2.67e-041653438a52f2dbcbd2bc1662b5e3fac381463fdcc3bf14
ToppCellCOPD-Lymphoid-ILC_B|COPD / Disease state, Lineage and Cell class

SSBP2 MAML3 INPP5D

2.71e-041663437609671e453280c6e522e9f659c06aab8be81945
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D122|Adult / Lineage, Cell type, age group and donor

INPP5D ZC3H12D MYO1F

2.71e-04166343be284e2e596390f05305c7bcfc316f87b963fc0b
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-Th1|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BCL2L11 CBLB MYO1F

2.76e-041673439c55ec8f70b86d4d3d5c2a6ecd9bff2dafe68c11
ToppCellnormal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T|normal_Pleural_Fluid / Location, Cell class and cell subclass

AKNA CBLB MYO1F

2.96e-041713436be81c20f4e962b414afcedfe478dd59c510d1e1
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

AKNA CBLB ZC3H12D

2.96e-041713432e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MOGS TONSL ZC3H12D

3.01e-04172343d824e46c8040b0bb9235f9b8a2b35386b303caa0
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MOGS TONSL ZC3H12D

3.01e-0417234310a1d1838492b8ce6dea08844353b51571432c56
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

INPP5D ZC3H12D MYO1F

3.01e-04172343ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA INPP5D MYO1F

3.01e-04172343f6b4754a7e4b3e38030316a0ae00d932bfa87e41
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA BMP6 INPP5D

3.06e-0417334362ba49c1c16760a8c6cde0cc44e068f94386946a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA INPP5D MYO1F

3.06e-0417334373f858f2c45d19b9ec8d99ac02c91551790f670c
ToppCellMild/Remission-B_naive-8|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SSBP2 CBLB MAML3

3.06e-04173343694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BMP6 LONRF3 CCDC28B

3.06e-041733434968712af1cca8c932abd3323631d7dcaffd4a66
ToppCellLV-17._Lymphocyte|World / Chamber and Cluster_Paper

AKNA INPP5D MYO1F

3.06e-04173343212f013ff761cbab24a537071739867c08c402a4
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LONRF3 SRCAP HCFC1

3.11e-04174343a1f745962a104c6f4b86b7e482da8755384c773a
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA ZC3H12D MYO1F

3.11e-04174343723848d2f8ae9cf4f15d4b4a130f9a64dab443c7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA INPP5D MYO1F

3.17e-04175343da92eb8af0c7c65fed4a1d960708240f35dd997d
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

LONRF3 SRCAP HCFC1

3.17e-0417534378a86cac3e6c0d115c997d1c29ee0e24af54551f
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP2 CCDC28B INPP5D

3.17e-04175343f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA INPP5D MYO1F

3.17e-041753432f43883d7c89f09b0579a390a7431f1f9b832582
ToppCellCOPD-Lymphoid-ILC_A|World / Disease state, Lineage and Cell class

AKNA CBLB INPP5D

3.17e-04175343e773e330de36f8a0aa9398a176ed7edb5599c582
ToppCellControl-B_cells|Control / group, cell type (main and fine annotations)

BMP6 BCL2L11 INPP5D

3.22e-041763439125caa27bf790f6b1b960a86c09b4bcb1b58641
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA BCL2L11 TSPYL4

3.22e-041763438e89471f838ea81235256cc2470f1c12c9b75f8a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA INPP5D MYO1F

3.22e-04176343926ed37e636fe4dd3a18731cea15761f0c2c285a
ToppCellCOPD-Lymphoid-ILC_A|COPD / Disease state, Lineage and Cell class

AKNA CBLB INPP5D

3.22e-04176343484452cb38fe4604f0910a068361ed461b5b0c21
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-B_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA INPP5D ZC3H12D

3.27e-04177343b07e6139618d888a9fd7cf43cad0d86a3f63e09e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-B_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA INPP5D ZC3H12D

3.27e-041773436376ec12322c04d5d37ec2fdc376700464cbc7fb
ToppCellControl-Lymphoid-ILC_B|Control / Disease state, Lineage and Cell class

SSBP2 CBLB INPP5D

3.27e-041773433d0f4b4054185ba77071efbe53df34fee84b9b24
ToppCellLA-17._Lymphocyte|World / Chamber and Cluster_Paper

AKNA INPP5D MYO1F

3.33e-0417834334ec499d03cc198cfefa19a724d4c81974052f65
ToppCellCOVID-19-kidney-Bcells|kidney / Disease (COVID-19 only), tissue and cell type

AKNA INPP5D ZC3H12D

3.44e-041803435650fc7ebcdf5e0be9a217a58d36a8386d59fd1b
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

AKNA CBLB MYO1F

3.44e-04180343f24d4cbba4cb50fce3b3d9c4629aa856d9b05358
ToppCellBronchial_Biopsy-Mesenchymal-Smooth_muscle|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

BMP6 ITGA7 CDK5R2

3.44e-041803437085a851807e6a833965e1366946db0bbc5174e2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA INPP5D MYO1F

3.44e-04180343c62417f205bcbf3b212ae177f63562ec6467c855
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA INPP5D MYO1F

3.44e-04180343bb2dbf7ed03d5ac765635b7afe738efa822841d0
ToppCellCOVID-19-kidney-NK|COVID-19 / Disease (COVID-19 only), tissue and cell type

AKNA INPP5D MYO1F

3.50e-041813438906ee8a7a1616dfe8c3b5c73988416641213629
ToppCellLV-17._Lymphocyte|LV / Chamber and Cluster_Paper

AKNA INPP5D MYO1F

3.50e-0418134381fafa69c8c240250a667a5f3b321e8be1b9a288
ToppCellLA-17._Lymphocyte|LA / Chamber and Cluster_Paper

AKNA INPP5D MYO1F

3.50e-041813433fd9f805fa46141b0fa7023ee5d8688d338635d5
ToppCellRA-17._Lymphocyte|RA / Chamber and Cluster_Paper

AKNA INPP5D MYO1F

3.55e-04182343257a7847917b6ea1d60608183d90300bfd028758
ToppCellIPF-Lymphoid-ILC_A|World / Disease state, Lineage and Cell class

AKNA CBLB INPP5D

3.55e-04182343f91bb45baaec76cb3bb26eedbcf0709b2492e93f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR1 CBLB MAML3

3.61e-041833433c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR1 CBLB MAML3

3.61e-04183343848fc6dd129150897ee339343e83c645b6e779eb
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR1 CBLB MAML3

3.61e-041833439c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellRA-17._Lymphocyte|World / Chamber and Cluster_Paper

AKNA INPP5D MYO1F

3.61e-041833436397f684a50346fc42cccb5afbe10350f4b2d9b0
ToppCellControl-APC-like-Dendritic_cells|Control / group, cell type (main and fine annotations)

BCL2L11 INPP5D MYO1F

3.61e-041833438f9c8e2436f18ea7c265b08e4e149e19cb513a16
ToppCellControl-APC-like|Control / group, cell type (main and fine annotations)

BCL2L11 INPP5D MYO1F

3.61e-04183343c313ac72cc9fa1583456d452393f61f0a4ca33a8
ToppCellIPF-Lymphoid-ILC_A|IPF / Disease state, Lineage and Cell class

AKNA CBLB INPP5D

3.61e-0418334349bfeaae13eb236f61a5486ee75c39789936bb8a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR1 CBLB MAML3

3.67e-041843437294b379ce4cb8fa75e432559082f93cd106aaf5
DrugSuxibuzone [27470-51-5]; Up 200; 9.2uM; HL60; HT_HG-U133A

RIPOR1 SSBP2 SNAPC2 PHF8 HCFC1 MAML3

4.67e-072003462503_UP
DrugNeomycin sulfate [1405-10-3]; Down 200; 4.2uM; MCF7; HT_HG-U133A

RIPOR1 HIVEP2 SNAPC2 BCL2L11 HCFC1

9.71e-061943457221_DN
DrugEthamsylate [2624-44-4]; Up 200; 15.2uM; MCF7; HT_HG-U133A

HIVEP2 SNAPC2 PHF8 SRCAP CCDC28B

1.02e-051963457335_UP
DrugLY 294002; Down 200; 10uM; MCF7; HT_HG-U133A

RIPOR1 SRCAP BCL2L11 HCFC1 MYO1F

1.05e-051973455236_DN
DrugHymecromone [90-33-5]; Down 200; 22.8uM; MCF7; HT_HG-U133A

BMP6 RIPOR1 LONRF3 BCL2L11 HCFC1

1.07e-051983455684_DN
Diseasevisceral adipose tissue measurement

SSBP2 HIVEP2 POM121C MAML3 ADCY8

2.12e-04481345EFO_0004765
DiseaseDuchenne muscular dystrophy, disease progression measurement

ADCY8 SHKBP1

1.52e-0350342EFO_0008336, MONDO_0010679
Diseaseeosinophil percentage of leukocytes

HIVEP2 BCL2L11 NDUFS2 INPP5D ZC3H12D

1.54e-03746345EFO_0007991
Diseasecolorectal health

CBLB ADCY8 IPMK

1.59e-03201343EFO_0008460
Diseasebody weight

BMP6 SSBP2 HIVEP2 BCL2L11 POM121C MAML3

2.90e-031261346EFO_0004338
DiseaseAdenoid Cystic Carcinoma

SRCAP MAML3

5.94e-03100342C0010606
Diseasegastroesophageal reflux disease

HIVEP2 MAML3

6.06e-03101342EFO_0003948
Diseaseeosinophil count

HIVEP2 BCL2L11 CBLB NDUFS2 INPP5D ZC3H12D

6.50e-031488346EFO_0004842

Protein segments in the cluster

PeptideGeneStartEntry
LGRVQPNPFILPPRR

ADCY8

1171

P40145
GRQLQPAERPPQLRP

BCL2L11

16

O43521
APPVPGGSPRRVIVQ

CDK5R2

166

Q13319
VSPGPRQQLPPRQLL

HCFC1

1506

P51610
VGQALPRPQAPPRLQ

MAML3

936

Q96JK9
VAVPRGRQPPQEPGV

CARMIL3

1281

Q8ND23
QVPLPPARRLPGENV

CBLB

866

Q13191
GTVLKQLQPPPRGPR

IPMK

71

Q8NFU5
QVLRPGAGVRLPIQP

NDUFS2

16

O75306
PRPPQGLVRVVGRPQ

MOGS

666

Q13724
RRGEQLTLPPPPQLG

POM121C

491

A8CG34
EQPPRGRNPGPRALQ

DMRTB1

121

Q96MA1
QRINIPPQRGPRPIR

G3BP1

306

Q13283
QQQLPRGEPPPGRLK

BMP6

116

P22004
QPRPTRQGRPLPRQG

AKNA

321

Q7Z591
LRRQAPGQGLPPVAP

ITGA7

646

Q13683
QPAQAPGTLRRVPVP

CCDC28B

16

Q9BUN5
QQRRIFLPPPPGIRK

DHX40

326

Q8IX18
RAQQPRAQEPPGRGP

GDF6

76

Q6KF10
RPPLRIPNQALGGVP

SSBP2

136

P81877
QLSPGLRPRPQVPGE

INPP5D

241

Q92835
VGPQQLGGRPAPVRR

SHKBP1

146

Q8TBC3
VVNNPRAPLGPVPVR

SRCAP

1011

Q6ZRS2
RVCPQVPVRLPRGPG

SPDYC

196

Q5MJ68
GPAPPPPIRVRVQVQ

TONSL

926

Q96HA7
PRRGIRGPPRQPVES

TSPYL4

391

Q9UJ04
PGRPQLPVQLRPQTR

ZNF211

6

Q13398
PPGLQLQPRGEHRPR

ZC3H12D

406

A2A288
AIVQRGRVLPPPAPL

PHF8

6

Q9UPP1
PIVLGPPNLRRGLPQ

HIVEP2

2166

P31629
QKLPRRPQPGPGEQL

RIPOR1

1026

Q6ZS17
LQGPRRREAQPPAPI

SNAPC2

86

Q13487
GARRAGQQPPPPLRV

LONRF3

211

Q496Y0
QRPVPGVGRPKPQPR

MYO1F

1026

O00160