Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transcription coregulator activity	KDM3A IL31RA ARID3A PPRC1 NACA NSD1 BCL11A DCC MED19 PIAS3 TLE2 DOT1L AJUBA TOX2 HCFC1 TRIM37	4.54e-05	562	178	16	GO:0003712
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RGPD2 ARHGEF28 TRIO RALGPS2 RAPGEF1 ARHGAP39 SIPA1 ARHGEF17 ASAP1 ARHGAP31 RALGPS1 ARHGEF1 KNDC1 ARHGAP33	1.88e-04	507	178	14	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RGPD2 ARHGEF28 TRIO RALGPS2 RAPGEF1 ARHGAP39 SIPA1 ARHGEF17 ASAP1 ARHGAP31 RALGPS1 ARHGEF1 KNDC1 ARHGAP33	1.88e-04	507	178	14	GO:0030695
Domain	PDZ	IL16 PDLIM7 SIPA1 PDLIM3 GRIP2 FRMPD3 AHNAK2 PDZD2	6.27e-05	141	178	8	PF00595
Domain	PDZ	IL16 PDLIM7 SIPA1 PDLIM3 GRIP2 FRMPD3 AHNAK2 PDZD2	8.81e-05	148	178	8	SM00228
Domain	-	IL16 PDLIM7 SIPA1 PDLIM3 GRIP2 FRMPD3 AHNAK2 PDZD2	9.68e-05	150	178	8	2.30.42.10
Domain	RASGEF	RALGPS2 RAPGEF1 RALGPS1 KNDC1	1.01e-04	26	178	4	PS00720
Domain	PDZ	IL16 PDLIM7 SIPA1 PDLIM3 GRIP2 FRMPD3 AHNAK2 PDZD2	1.01e-04	151	178	8	PS50106
Domain	PDZ	IL16 PDLIM7 SIPA1 PDLIM3 GRIP2 FRMPD3 AHNAK2 PDZD2	1.06e-04	152	178	8	IPR001478
Domain	RASGEF_CAT	RALGPS2 RAPGEF1 RALGPS1 KNDC1	1.57e-04	29	178	4	PS50009
Domain	RasGEF	RALGPS2 RAPGEF1 RALGPS1 KNDC1	1.80e-04	30	178	4	PF00617
Domain	-	RALGPS2 RAPGEF1 RALGPS1 KNDC1	1.80e-04	30	178	4	1.10.840.10
Domain	RASGEF_cat_dom	RALGPS2 RAPGEF1 RALGPS1 KNDC1	1.80e-04	30	178	4	IPR001895
Domain	RasGEF	RALGPS2 RAPGEF1 RALGPS1 KNDC1	1.80e-04	30	178	4	SM00147
Domain	Ras_GEF_dom	RALGPS2 RAPGEF1 RALGPS1 KNDC1	1.80e-04	30	178	4	IPR023578
Domain	PH_dom-like	RGPD2 ARHGEF28 TRIO RALGPS2 IRS1 ARHGEF17 ASAP1 PHLDB1 CMIP RALGPS1 ARHGEF1 TLN1 FRMPD3	2.32e-04	426	178	13	IPR011993
Domain	ZnF_DBF	DBF4B ZDBF2	2.69e-04	3	178	2	SM00586
Domain	ZF_DBF4	DBF4B ZDBF2	2.69e-04	3	178	2	PS51265
Domain	Znf_DBF	DBF4B ZDBF2	2.69e-04	3	178	2	IPR006572
Domain	REKLES	ARID3A ARID3B	2.69e-04	3	178	2	PS51486
Domain	REKLES_domain	ARID3A ARID3B	2.69e-04	3	178	2	IPR023334
Domain	muHD	SGIP1 FCHO2	2.69e-04	3	178	2	PF10291
Domain	zf-DBF	DBF4B ZDBF2	2.69e-04	3	178	2	PF07535
Domain	Muniscin_C	SGIP1 FCHO2	2.69e-04	3	178	2	IPR018808
Domain	Post-SET_dom	ASH1L NSD1 EHMT2	4.35e-04	16	178	3	IPR003616
Domain	PostSET	ASH1L NSD1 EHMT2	4.35e-04	16	178	3	SM00508
Domain	POST_SET	ASH1L NSD1 EHMT2	4.35e-04	16	178	3	PS50868
Domain	AWS	ASH1L NSD1	8.86e-04	5	178	2	SM00570
Domain	AWS	ASH1L NSD1	8.86e-04	5	178	2	PS51215
Domain	AWS_dom	ASH1L NSD1	8.86e-04	5	178	2	IPR006560
Pathway	REACTOME_RHO_GTPASE_CYCLE	SLK ARHGEF28 TRIO DSP RAPGEF1 ARHGAP39 ARHGEF17 ARHGAP31 ARHGEF1 NISCH FAM135A PHIP ARHGAP33	7.08e-05	439	117	13	MM15595
Pathway	REACTOME_RHO_GTPASE_CYCLE	SLK ARHGEF28 TRIO DSP RAPGEF1 ARHGAP39 ARHGEF17 ARHGAP31 ARHGEF1 NISCH FAM135A PHIP ARHGAP33	9.08e-05	450	117	13	M27078
Pathway	REACTOME_CHROMATIN_MODIFYING_ENZYMES	KDM3A ASH1L NSD1 KANSL3 KDM4D EHMT2 DOT1L HCFC1	1.04e-04	175	117	8	MM14941
Pathway	REACTOME_RHOA_GTPASE_CYCLE	SLK ARHGEF28 TRIO ARHGAP39 ARHGEF17 ARHGAP31 ARHGEF1	1.79e-04	142	117	7	MM15576
Pathway	WP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY	KDM3A EP400 IRS1 ARID3B TGFB1 DFFA EHMT2 DPPA4 TLE2 HCFC1	2.02e-04	301	117	10	MM15983
Pathway	REACTOME_RHOA_GTPASE_CYCLE	SLK ARHGEF28 TRIO ARHGAP39 ARHGEF17 ARHGAP31 ARHGEF1	2.41e-04	149	117	7	M41805
Pathway	REACTOME_RHOB_GTPASE_CYCLE	SLK ARHGEF28 ARHGAP39 ARHGEF17 ARHGEF1	2.66e-04	69	117	5	MM15596
Pathway	REACTOME_RHOB_GTPASE_CYCLE	SLK ARHGEF28 ARHGAP39 ARHGEF17 ARHGEF1	2.85e-04	70	117	5	M41806
Pathway	REACTOME_RHOC_GTPASE_CYCLE	SLK ARHGEF28 ARHGAP39 ARHGEF17 ARHGEF1	2.85e-04	70	117	5	MM15597
Pathway	REACTOME_RHOC_GTPASE_CYCLE	SLK ARHGEF28 ARHGAP39 ARHGEF17 ARHGEF1	3.69e-04	74	117	5	M41807
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SYNRG ARID3A EP400 TRIO LAT2 PPRC1 TMEM94 INTS1 PSMB10 NSD1 RAPGEF1 IRS1 KANSL3 PHLDB1 ZC3H11A C2CD3 ZBED4 RALGPS1 NISCH TTLL4 TLN1 PKD1 NAV2 ZFYVE26 UBE3C DOT1L HECTD1 HCFC1 ARHGAP33 AHNAK2	3.07e-13	1105	187	30	35748872
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SLK EP400 PPRC1 TMEM94 HEATR5A BCL11A ARHGEF17 VIRMA ASAP1 PHLDB1 ZC3H11A ZBED4 PHF3 NISCH TLN1 UBE3C CAMSAP2 PDZD2	1.01e-11	407	187	18	12693553
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	KDM3A SYNRG ARID3A EP400 TACC2 CTTNBP2NL ARID3B KANSL3 ZC3H11A PIAS3 SLF2 PHF3 TLN1 SUGP1 MTRR HCFC1 CCDC102A AHNAK2	4.19e-11	444	187	18	34795231
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KDM3A SYNRG SLK CEP85 EP400 TCOF1 DSP PDLIM7 NSD1 ARID3B ZC3H11A PHF3 TLN1 AMOTL1 DOT1L HCFC1 RSBN1L CUX1	1.26e-09	549	187	18	38280479
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SYNRG HIVEP1 ARHGEF28 TRIO DSP MBD1 RALGPS2 IRS1 ARHGEF17 VIRMA E2F8 PHLDB1 C2CD3 SLF2 PHF3 ARHGEF1 NAV2 CAMSAP2 HECTD1 CCDC102A AHNAK2	9.51e-09	861	187	21	36931259
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	TBRG4 TCOF1 TACC2 FCHO2 IPO4 POLR1G CTTNBP2NL PDCD4 DFFA ZC3H11A NFATC2IP EHMT2 PHF3 NAV2 BAG6 HCFC1	1.66e-08	503	187	16	16964243
Pubmed	A human MAP kinase interactome.	HIVEP1 DSP SREBF2 RAPGEF1 EVPL NCKAP5 ASAP1 TGFB1 KIAA1549L PIAS3 ARHGAP31 ARHGEF1 NAV2 CUX1 ARHGAP33	6.99e-08	486	187	15	20936779
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	SYNRG HIVEP1 CEP85 EP400 TCOF1 DSP TACC2 ZDBF2 IPO4 KANSL3 NFATC2IP SLF2 TSEN34 DOT1L FAM135A TRIM37	1.40e-07	588	187	16	38580884
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	HIVEP1 EP400 RFX5 ARID3B KANSL3 NFATC2IP EHMT2 PHF3 SUGP1 HCFC1 CUX1	2.55e-07	268	187	11	33640491
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	KDM3A CEP85 TRIO TCOF1 DSP PPRC1 MBD1 ASH1L AIRE NCKAP5 GRIN2B CMYA5 UBASH3A RFX5 PIAS3 EHMT2 SLF2 NISCH PKD1 HECTD1 TRIM37 RSBN1L CUX1	4.85e-07	1285	187	23	35914814
Pubmed	New nomenclature for chromatin-modifying enzymes.	KDM3A ASH1L NSD1 KDM4D EHMT2 DOT1L	6.44e-07	57	187	6	18022353
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	CEP85 DSP RFX5 ZC3H11A C2CD3 ARHGAP31 CAMSAP2 TRIM37 CCDC102A	7.54e-07	184	187	9	32908313
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	KDM3A HIVEP1 ARID3A ZNF280C INTS1 NSD1 RFX5 ARID3B NFATC2IP EHMT2 PHF3 DOT1L HCFC1 PHIP CUX1	1.19e-06	608	187	15	36089195
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RGPD2 SLK SGIP1 TRIO TCOF1 NHSL2 NSD1 BCL11A GRIN2B ARHGAP39 SIPA1 IPO4 VIRMA NLGN3 EHMT2 NISCH FRMPD3 CAMSAP2 CUX1	1.25e-06	963	187	19	28671696
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	SLK TCOF1 DSP PDLIM7 NACA ZDBF2 TLN1 SUGP1 HCFC1 AHNAK2	1.41e-06	256	187	10	33397691
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	PPRC1 ASH1L RALGPS2 SREBF2 NSD1 TACC2 NCSTN FCHO2 TUB E2F8 ASAP1 NLGN3 ZC3H11A ARHGEF1 VCAN TTLL4 DOT1L FAM135A TRIM37 PARP12	1.81e-06	1084	187	20	11544199
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	INTS1 ASH1L HEATR5A VIRMA CTTNBP2NL KANSL3 NAV2 FAM135A	1.91e-06	153	187	8	10718198
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	TUT4 HIVEP1 DBF4B MBD1 RABAC1 TACC2 BCL11A SIPA1 NLGN3 PHLDB1 KIAA1549L PIAS3 GRIP2 PYCR2	2.34e-06	560	187	14	21653829
Pubmed	Histone H2A ubiquitination inhibits the enzymatic activity of H3 lysine 36 methyltransferases.	ASH1L NSD1 EHMT2	3.02e-06	6	187	3	24019522
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	SYNRG SLK EP400 TCOF1 DSP ZNF280C NACA TACC2 PDCD4 ZC3H11A PDLIM3 TLN1 SUGP1 CAMSAP2 HCFC1 RSBN1L PARP12 AHNAK2	3.36e-06	934	187	18	33916271
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	HIVEP1 EP400 DSP ZNF280C NSD1 ZDBF2 RFX5 ARID3B ZC3H11A MED19 SLF2 PHF3 SUGP1 ZNF830 HCFC1 PHIP RSBN1L CUX1	4.49e-06	954	187	18	36373674
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KDM3A TBRG4 EP400 ZNF280C NACA NCSTN CTTNBP2NL KANSL3 ARHGAP31 RALGPS1 TTLL4 NAV2 CACNA1G	6.53e-06	529	187	13	14621295
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	KDM3A NSD1 KDM4D EHMT2 DOT1L	6.70e-06	49	187	5	34368113
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	TCOF1 NACA ARHGAP39 POLR1G CTTNBP2NL AMER2 PHF3 ZNF830 CAMSAP2	8.14e-06	246	187	9	15345747
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	KLF11 HIVEP1 ARID3A MLX MBD1 ZNF280C ASH1L AIRE RFX5 ARID3B ZBED4 PIAS3 ZNF830 AJUBA CUX1 PARP12	8.61e-06	808	187	16	20412781
Pubmed	Proximity labeling reveals dynamic changes in the SQSTM1 protein network.	SYNRG TBRG4 TUT4 CEP85 PDLIM7 PDLIM3 AMOTL1 FER MTRR CCDC102A	1.07e-05	322	187	10	39098523
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	TUT4 EP400 TRIO TMEM94 NACA ZDBF2 ARID3B PHF3 TTLL4 AMOTL1 SUGP1 UBE3C HECTD1 HCFC1 RSBN1L	1.13e-05	733	187	15	34672954
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	RGPD2 EP400 INTS1 ARID3B EHMT2 HCFC1 MOV10	1.50e-05	146	187	7	23892456
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	TUT4 EP400 TCOF1 DSP PPRC1 DBF4B NACA ADGB PHLDB1 NDC1 EHMT2 TNFRSF8 CACNA1G GRIP2 MOV10	1.57e-05	754	187	15	35906200
Pubmed	Modulation of gene expression in the preimplantation mouse embryo by TGF-alpha and TGF-beta.	TBRG4 TGFB1 TBRG1	1.79e-05	10	187	3	7654366
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	EP400 PDLIM7 MBD1 NACA INTS1 NSD1 ARHGAP39 IPO4 POLR1G VIRMA CTTNBP2NL BDH1 ZC3H11A MED19 MICALL2 EHMT2 PHF3 TLN1 GORAB CAMSAP2 RSBN1L MOV10	2.00e-05	1497	187	22	31527615
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	ARID3A EP400 INTS1 ZDBF2 IPO4 ARID3B ZFHX4 EHMT2 CUX1	2.40e-05	282	187	9	23667531
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	EP400 ZNF280C ARID3B ZC3H11A PHF3 SUGP1 ZNF830 HCFC1 RSBN1L	2.47e-05	283	187	9	30585729
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	SLK TCOF1 ZNF280C NACA EVPL SIPA1 EHMT2 ARHGEF1 TLN1 AHNAK2	2.79e-05	360	187	10	33111431
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	KLF11 HIVEP1 LAT2 PDLIM7 MBD1 KIAA1549L CACNA1G GRIP2 PYCR2 AJUBA CAMSAP2 BAG6 TRIM37	2.81e-05	608	187	13	16713569
Pubmed	The tumor suppressor KLF11 mediates a novel mechanism in transforming growth factor beta-induced growth inhibition that is inactivated in pancreatic cancer.	KLF11 TGFB1	2.88e-05	2	187	2	17114344
Pubmed	The hypoxia-inducible epigenetic regulators Jmjd1a and G9a provide a mechanistic link between angiogenesis and tumor growth.	KDM3A EHMT2	2.88e-05	2	187	2	25071150
Pubmed	G9a and Jhdm2a regulate embryonic stem cell fusion-induced reprogramming of adult neural stem cells.	KDM3A EHMT2	2.88e-05	2	187	2	18535151
Pubmed	TGF-β Induces Endometriotic Progression via a Noncanonical, KLF11-Mediated Mechanism.	KLF11 TGFB1	2.88e-05	2	187	2	27384304
Pubmed	A dual role for talin in NK cell cytotoxicity: activation of LFA-1-mediated cell adhesion and polarization of NK cells.	ITGAL TLN1	2.88e-05	2	187	2	19124737
Pubmed	Characterization of LILRB3 and LILRA6 allelic variants in the Japanese population.	LILRB3 LILRA6	2.88e-05	2	187	2	33526815
Pubmed	A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes.	ITGAL TLN1	2.88e-05	2	187	2	15983060
Pubmed	The protein-tyrosine kinase fer associates with signaling complexes containing insulin receptor substrate-1 and phosphatidylinositol 3-kinase.	IRS1 FER	2.88e-05	2	187	2	11006284
Pubmed	Gly972Arg of IRS-1 and Lys121Gln of PC-1 polymorphisms act in opposite way in polycystic ovary syndrome.	IRS1 PKD1	2.88e-05	2	187	2	27785750
Pubmed	Distinct frequency patterns of LILRB3 and LILRA6 allelic variants in Europeans.	LILRB3 LILRA6	2.88e-05	2	187	2	36449053
Pubmed	The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific trans-activator that describes a new DNA-binding protein family.	ARID3A ARID3B	2.88e-05	2	187	2	8543152
Pubmed	Discovering regulators of centriole biogenesis through siRNA-based functional genomics in human cells.	C2CD3 TRIM37	2.88e-05	2	187	2	23769972
Pubmed	ARID3A and ARID3B induce stem promoting pathways in ovarian cancer cells.	ARID3A ARID3B	2.88e-05	2	187	2	32061921
Pubmed	[High expression of CAMSAP2 promotes invasion and metastasis of gastric cancer cells by upregulating TGF-β signaling].	TGFB1 CAMSAP2	2.88e-05	2	187	2	37814859
Pubmed	The relationship of promoter methylation of calcium voltage-gated channel alpha 1 and interleukin-16 to primary osteoarthritis.	IL16 CACNA1G	2.88e-05	2	187	2	37259724
Pubmed	Allogeneic disparities in immunoglobulin-like transcript 5 induce potent antibody responses in hematopoietic stem cell transplant recipients.	LILRB3 LILRA6	2.88e-05	2	187	2	19617579
Pubmed	Bcl11A/CTIP1 regulates expression of DCC and MAP1b in control of axon branching and dendrite outgrowth.	BCL11A DCC	2.88e-05	2	187	2	19616629
Pubmed	High frequency of matrix attachment regions and cut-like protein x/CCAAT-displacement protein and B cell regulator of IgH transcription binding sites flanking Ig V region genes.	ARID3A CUX1	2.88e-05	2	187	2	12193717
Pubmed	Diversity of the human LILRB3/A6 locus encoding a myeloid inhibitory and activating receptor pair.	LILRB3 LILRA6	2.88e-05	2	187	2	24096970
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	EP400 ATXN7L1 ARID3B PIAS3 SLF2 SUGP1 PYCR2 HCFC1	2.91e-05	222	187	8	37071664
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	IL16 SLK SGIP1 TRIO DSP BCL11A GRIN2B ARHGAP39 SIPA1 ARHGEF17 VIRMA ASAP1 NLGN3 PHLDB1 ARHGEF1 NISCH VCAN TLN1 KNDC1 PYCR2 CAMSAP2	3.19e-05	1431	187	21	37142655
Pubmed	Proteomic profiling of Myc-associated proteins.	TUT4 EP400 PDLIM7 MICALL2 KNDC1 PDZD2	3.67e-05	114	187	6	21150319
Pubmed	USP7 Regulates Cytokinesis through FBXO38 and KIF20B.	HIVEP1 EP400 BCL11A EHMT2 BAG6 CUX1	4.05e-05	116	187	6	30804394
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	TBRG4 TUT4 HIVEP1 ARHGEF28 MLX DBF4B MBD1 ZNF280C SREBF2 C11orf24 IPO4 RFX5 ARHGEF1 TLN1 PKD1 TSEN34	4.42e-05	925	187	16	28986522
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	RGPD2 SYNRG TUT4 SGIP1 TRIO DSP NACA TACC2 ZDBF2 GRIN2B ARHGAP39 KCNB2 BDH1 ASAP1 AMER2 KNDC1 PYCR2 CAMSAP2	4.73e-05	1139	187	18	36417873
Pubmed	Extensive gene duplications and a large inversion characterize the human leukocyte receptor cluster.	LILRB3 LILRA6 TSEN34	5.33e-05	14	187	3	10941842
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	CEP85 EP400 TRIO ZNF280C NACA FCHO2 CTTNBP2NL ASAP1 KANSL3 PHF3 CUX1	5.48e-05	472	187	11	38943005
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TCOF1 DSP INTS1 NSD1 IPO4 VIRMA ZC3H11A PHF3 TLN1 HECTD1 HCFC1 PHIP MOV10	5.83e-05	653	187	13	22586326
Pubmed	Bioinformatics and cellular signaling.	IL16 HIVEP1 PPRC1 SREBF2 RAPGEF1 ARHGEF1 BAG6	6.14e-05	182	187	7	15102471
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	DSP INTS1 SREBF2 IPO4 ZC3H11A CMIP TLN1 HECTD1 BAG6	6.71e-05	322	187	9	26514267
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	MLX EP400 TCOF1 DSP MBD1 INTS1 NSD1 POLR1G RFX5 KANSL3 ZC3H11A NDC1 TBRG1 ZBED4 EHMT2 SLF2 PHF3 HCFC1 CUX1	7.68e-05	1294	187	19	30804502
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	AIRE RAPGEF1 NCKAP5 KCNB2 ASAP1 PPP1R3D EHMT2 PKD1 GRIP2	7.91e-05	329	187	9	17474147
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KDM3A SYNRG HIVEP1 EP400 TCOF1 DSP ARHGAP39 POLR1G VIRMA CTTNBP2NL KANSL3 ZC3H11A PHF3 BAG6	8.40e-05	774	187	14	15302935
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	TRIO NSD1 ZC3H11B ZC3H11A ZBED4 TLN1 AMOTL1 SHOC1 AHNAK2	8.47e-05	332	187	9	37433992
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	EP400 SPR PDCD4 ZC3H11A NFATC2IP PHF3 TLN1 HCFC1 AHNAK2	8.47e-05	332	187	9	32786267
Pubmed	A Pkd1-Fbn1 genetic interaction implicates TGF-β signaling in the pathogenesis of vascular complications in autosomal dominant polycystic kidney disease.	TGFB1 PKD1	8.60e-05	3	187	2	24071006
Pubmed	ARID proteins come in from the desert.	ARID3A ARID3B	8.60e-05	3	187	2	10838570
Pubmed	Ectopic expression of Cux1 is associated with reduced p27 expression and increased apoptosis during late stage cyst progression upon inactivation of Pkd1 in collecting ducts.	PKD1 CUX1	8.60e-05	3	187	2	21465620
Pubmed	Ursolic acid inhibits proliferation and induces apoptosis in human glioblastoma cell lines U251 by suppressing TGF-β1/miR-21/PDCD4 pathway.	PDCD4 TGFB1	8.60e-05	3	187	2	22353043
Pubmed	Cux1 promotes cell proliferation and polycystic kidney disease progression in an ADPKD mouse model.	PKD1 CUX1	8.60e-05	3	187	2	28701314
Pubmed	Immunoproteasomes Control the Homeostasis of Medullary Thymic Epithelial Cells by Alleviating Proteotoxic Stress.	PSMB10 AIRE	8.60e-05	3	187	2	29186691
Pubmed	STED nanoscopy of the centrosome linker reveals a CEP68-organized, periodic rootletin network anchored to a C-Nap1 ring at centrioles.	CEP68 DOT1L	8.60e-05	3	187	2	29463719
Pubmed	Tieg3/Klf11 induces apoptosis in OLI-neu cells and enhances the TGF-beta signaling pathway by transcriptional repression of Smad7.	KLF11 TGFB1	8.60e-05	3	187	2	18189266
Pubmed	Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin.	DSP EVPL	8.60e-05	3	187	2	9412476
Pubmed	Cloning and characterization of PHIP, a novel insulin receptor substrate-1 pleckstrin homology domain interacting protein.	IRS1 PHIP	8.60e-05	3	187	2	11018022
Pubmed	Ceramides are bound to structural proteins of the human foreskin epidermal cornified cell envelope.	DSP EVPL	8.60e-05	3	187	2	9651377
Pubmed	Heat-stable antigen is a costimulatory molecule for CD4 T cell growth.	ITGAL TGFB1	8.60e-05	3	187	2	1346270
Pubmed	Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s.	TUT4 MOV10	8.60e-05	3	187	2	30122351
Pubmed	Distinct and overlapping roles of ARID3A and ARID3B in regulating E2F‑dependent transcription via direct binding to E2F target genes.	ARID3A ARID3B	8.60e-05	3	187	2	33649863
Pubmed	CCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcription.	EHMT2 CUX1	8.60e-05	3	187	2	15269344
Pubmed	Cellular growth inhibition by TGF-beta1 involves IRS proteins.	IRS1 TGFB1	8.60e-05	3	187	2	15135063
Pubmed	Bat3 facilitates H3K79 dimethylation by DOT1L and promotes DNA damage-induced 53BP1 foci at G1/G2 cell-cycle phases.	DOT1L BAG6	8.60e-05	3	187	2	22373577
Pubmed	CRKL, AIFM3, AIF, BCL2, and UBASH3A during Human Kidney Development.	UBASH3A AIFM3	8.60e-05	3	187	2	34502088
Pubmed	DOT1L O-GlcNAcylation promotes its protein stability and MLL-fusion leukemia cell proliferation.	UBE3C DOT1L	8.60e-05	3	187	2	34551297
Pubmed	PGC-1-related coactivator complexes with HCF-1 and NRF-2beta in mediating NRF-2(GABP)-dependent respiratory gene expression.	PPRC1 HCFC1	8.60e-05	3	187	2	18343819
Pubmed	TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells.	TGFB1 VCAN	8.60e-05	3	187	2	37461061
Pubmed	The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance.	MBD1 AIRE	8.60e-05	3	187	2	24464130
Pubmed	TGF-β1 promotes osteosarcoma cell migration and invasion through the miR-143-versican pathway.	TGFB1 VCAN	8.60e-05	3	187	2	25562163
Pubmed	The ARID family transcription factor bright is required for both hematopoietic stem cell and B lineage development.	ARID3A ARID3B	8.60e-05	3	187	2	21199920
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	ARID3A EP400 NSD1 ARID3B CUX1	8.81e-05	83	187	5	28794006
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	EP400 ARID3B KANSL3 ZC3H11A SUGP1 HCFC1	9.05e-05	134	187	6	25452129
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	MARS2 SLK TBRG4 HIVEP1 TRIO TCOF1 DSP ZNF280C NACA IPO4 CMYA5 DFFA ZC3H11A NDC1 TLN1 UBE3C PYCR2 BAG6 HCFC1 PHIP	9.13e-05	1425	187	20	30948266
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	NACA GRIN2B ARHGAP39 DCC KCNB2 KNDC1 CAMSAP2	1.01e-04	197	187	7	36604605
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	RGPD2 ZC3H11A PHF3 HCFC1 PHIP	1.04e-04	86	187	5	37253089
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	MARS2 CEP85 PDLIM7 NACA RABAC1 NCSTN TGFB1 EFNB1 PDLIM3 GORAB SUGP1 ZNF830 PYCR2 FAM135A RSBN1L MOV10	1.19e-04	1007	187	16	34597346
Interaction	H3C1 interactions	ARID3A DSP ZNF280C NACA INTS1 ASH1L NSD1 AIRE IPO4 POLR1G RFX5 VIRMA PDCD4 PIEZO2 MICALL2 EHMT2 PHF3 NAV2 ZNF830 PHIP RSBN1L CUX1 MOV10 PDZD2	2.08e-06	901	182	24	int:H3C1
Interaction	PHLPP1 interactions	SLK TCOF1 DSP PDLIM7 NACA ZDBF2 FCHO2 CMYA5 VIRMA EFNB1 TLN1 SUGP1 HCFC1 AHNAK2	2.13e-06	333	182	14	int:PHLPP1
Interaction	TERF2IP interactions	KDM3A HIVEP1 ARID3A EP400 ZNF280C INTS1 NSD1 RFX5 PDCD4 KANSL3 ZC3H11A NFATC2IP PHF3 SUGP1 ZNF830 HECTD1 HCFC1 CUX1	2.81e-06	552	182	18	int:TERF2IP
Interaction	TOP3B interactions	SYNRG ARID3A EP400 TRIO LAT2 PPRC1 TMEM94 INTS1 PSMB10 NSD1 RAPGEF1 IRS1 IPO4 KANSL3 PHLDB1 ZC3H11A C2CD3 ZBED4 RALGPS1 NISCH TTLL4 TLN1 PKD1 NAV2 ZFYVE26 UBE3C DOT1L HECTD1 HCFC1 ARHGAP33 MOV10 AHNAK2	2.87e-06	1470	182	32	int:TOP3B
Interaction	FBXO38 interactions	HIVEP1 EP400 ATXN7L1 BCL11A VIRMA EHMT2 BAG6 CUX1 MOV10	6.93e-06	145	182	9	int:FBXO38
Interaction	EN1 interactions	HIVEP1 ARID3A EP400 ARID3B ZFHX4 TLE2 TRIM37 CUX1	7.09e-06	110	182	8	int:EN1
Interaction	AR interactions	KDM3A HIVEP1 EP400 DSP NSD1 IPO4 DCC RFX5 VIRMA ARID3B KANSL3 KDM4D PIAS3 NFATC2IP EHMT2 PHF3 NISCH SUGP1 TSEN34 DOT1L BAG6 HCFC1 CUX1 PARP12	1.06e-05	992	182	24	int:AR
Interaction	OTUD7A interactions	NACA GRIN2B KCNB2 VIRMA KNDC1 CAMSAP2	1.37e-05	58	182	6	int:OTUD7A
Interaction	YWHAG interactions	SYNRG SLK HIVEP1 ARHGEF28 MLX DSP NHSL2 MBD1 RALGPS2 IRS1 SIPA1 ARHGEF17 VIRMA PDCD4 E2F8 PPP1R3D DFFA PHLDB1 C2CD3 PHF3 ARHGEF1 NAV2 CAMSAP2 HECTD1 CCDC102A AHNAK2	5.78e-05	1248	182	26	int:YWHAG
Interaction	HNF1B interactions	HIVEP1 ARID3A EP400 TCOF1 ARID3B TGFB1 ZFHX4 TRIM37 CUX1	5.93e-05	190	182	9	int:HNF1B
Interaction	MCF2L interactions	SLK RABAC1 VIRMA MOV10	5.94e-05	24	182	4	int:MCF2L
Interaction	H2BC21 interactions	EP400 ATXN7L1 DBF4B ZNF280C NSD1 AIRE VIRMA PDCD4 KDM4D C2CD3 KIAA1549L EHMT2 PHF3 TLN1 FER PYCR2 HCFC1 PHIP	6.26e-05	696	182	18	int:H2BC21
GeneFamily	PDZ domain containing	IL16 PDLIM7 SIPA1 PDLIM3 GRIP2 FRMPD3 AHNAK2 PDZD2	4.71e-06	152	112	8	1220
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	ASH1L NSD1 EHMT2 DOT1L	5.61e-05	34	112	4	487
GeneFamily	Zinc fingers DBF-type	DBF4B ZDBF2	1.14e-04	3	112	2	75
GeneFamily	LIM domain containing	PDLIM7 PDLIM3 MICALL2 AJUBA	4.89e-04	59	112	4	1218
GeneFamily	EF-hand domain containing\|Plakins	DSP EVPL	1.04e-03	8	112	2	939
GeneFamily	Zinc fingers CCCH-type	ZC3H11B ZC3H11A PARP12	1.31e-03	35	112	3	73
GeneFamily	PHD finger proteins	ASH1L NSD1 AIRE PHF3	2.37e-03	90	112	4	88
GeneFamily	Fibronectin type III domain containing	IL31RA DCC CMYA5 LRRN4 USH2A	3.20e-03	160	112	5	555
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP39 ARHGAP31 ARHGAP33	3.67e-03	50	112	3	721
GeneFamily	AT-rich interaction domain containing	ARID3A ARID3B	3.79e-03	15	112	2	418
Coexpression	GSE22103_LPS_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_DN	MARS2 SLK PPRC1 MBD1 ZNF280C C11orf24 TACC2 TTLL4 TMEM65 MTRR	1.78e-06	200	186	10	M7791
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_28DY_DN	LILRB3 TUT4 MBD1 INTS1 LILRA6 AIRE RAPGEF1 NCSTN ITGAL ARID3B CMIP NFATC2IP FCGRT RALGPS1 NISCH SUGP1 ZFYVE26 HCFC1 CUX1 ARHGAP33	7.43e-06	905	186	20	M40865
Coexpression	GSE41867_DAY6_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN	RALGPS2 NSD1 RAPGEF1 ITGAL PDCD4 ZC3H11A CMIP FCGRT TLN1	1.38e-05	200	186	9	M9459
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	ARHGEF28 RAPGEF1 CTTNBP2NL PDCD4 CFAP54 CMIP ARHGAP31 TOX2 FAM135A	1.02e-07	187	187	9	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIO NCKAP5 IRS1 BDH1 E2F8 NLGN3 KIAA1549L VCAN	1.01e-06	181	187	8	4e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIO NCKAP5 IRS1 BDH1 E2F8 NLGN3 KIAA1549L VCAN	1.01e-06	181	187	8	ad30c01290fb98adbd0caed301a584761212c977
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIO NCKAP5 IRS1 BDH1 E2F8 NLGN3 KIAA1549L VCAN	1.01e-06	181	187	8	3a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PDLIM7 IRS1 TACC2 PHLDB1 PDLIM3 VCAN AMOTL1 NAV2	1.20e-06	185	187	8	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	TUT4 HIVEP1 ARHGEF28 DSP PHF3 VCAN FER PHIP	1.64e-06	193	187	8	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-suprabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF28 DSP EVPL PDCD4 PHLDB1 TMEM65 PSAPL1 CUX1	1.71e-06	194	187	8	a3adcdc8b87332e8beb9bcd70cf36424af10633d
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASH1L NSD1 FCHO2 PDCD4 ASAP1 SCUBE2 ARHGAP31 HECTD1	1.71e-06	194	187	8	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADCY10 GRIN2B SIM1 KIAA1549L DPPA4 AIFM3 USH2A	5.67e-06	162	187	7	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	CV-Healthy-4\|Healthy / Virus stimulation, Condition and Cluster	KDM3A TRIO PDLIM7 VWA7 UBASH3A AMOTL1 FRMPD3	9.05e-06	174	187	7	26544cc5f51cb4dc1251e62d9f80b6c956194d38
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	IL16 SGIP1 NHSL2 DCC PIEZO2 PDLIM3 NAV2	1.44e-05	187	187	7	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PDLIM7 IRS1 TACC2 PHLDB1 PDLIM3 AMOTL1 NAV2	1.50e-05	188	187	7	4d1e5f85342ae550086609d7680e32730b78b5d2
ToppCell	COVID-19-Epithelial-Ionocytes\|COVID-19 / Condition, Lineage and Cell class	DSP IRS1 TACC2 SCUBE2 NAV2 FUT2 PDZD2	1.50e-05	188	187	7	a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	TUT4 HIVEP1 ARHGEF28 DSP PHF3 VCAN PHIP	1.71e-05	192	187	7	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	TRIO ATXN7L1 ASH1L NCKAP5 CMIP CUX1 PDZD2	1.71e-05	192	187	7	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ADCY10 AIRE DCC ITGAL AHNAK2	1.82e-05	77	187	5	a799ccdb84014e978d9fbccf3d2fee8fbeac7b0c
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PDLIM7 IRS1 TACC2 PDLIM3 AMOTL1 TACR2 TSGA10IP	2.16e-05	199	187	7	a207b4891881149d4c50721310690fd794157723
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IL16 SGIP1 NHSL2 PIEZO2 PDLIM3 NAV2 TOX2	2.23e-05	200	187	7	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	Tracheal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SGIP1 NHSL2 NCKAP5 ARHGEF17 PHLDB1 GRIP2 PSAPL1	2.23e-05	200	187	7	9d3ae9ea47b1017adb63aa02d10e98193d478458
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LILRB3 LAT2 LILRA6 BCL11A IPO4 BDH1	4.46e-05	152	187	6	87a7116d0064a6051bdf28ce1e48bfc168273e66
ToppCell	B_cells-ABCs\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ARID3A LAT2 RALGPS2 BCL11A E2F8 TOX2	6.80e-05	164	187	6	f45013706a917f0f0d69c23f288128f252cd60c7
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TUT4 TRIO DSP RALGPS2 BCL11A ZC3H11A	7.04e-05	165	187	6	fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCell	facs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LILRB3 ARID3A LILRA6 C11orf24 KANSL3 UBE3C	7.52e-05	167	187	6	528493896aebe7d03d4b6ad2341b12927859e2e4
ToppCell	facs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LILRB3 ARID3A LILRA6 C11orf24 KANSL3 UBE3C	7.52e-05	167	187	6	a82e85caf79395baa48380786d9df32a86dfd1ce
ToppCell	P28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ARHGEF28 EVPL IRS1 POLR1G ARHGEF17 NLGN3	7.77e-05	168	187	6	8c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell	Control-B_naive-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 DSP TMEM94 VIRMA ZC3H11A SLF2	8.57e-05	171	187	6	d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 EFNB1 ARHGAP31 AMOTL1 GRIP2 TOX2	9.14e-05	173	187	6	afa6bb19df52541d8d17cbfac9cbdd18a5f3632d
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLF11 PDLIM7 SCUBE2 PDLIM3 TACR2 AHNAK2	1.00e-04	176	187	6	a8875b4ba4abf6625cdeb67bf544ce1573c59060
ToppCell	facs-Lung-Endomucin-3m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL16 LAT2 RALGPS2 BDH1 PDCD4 NFATC2IP	1.00e-04	176	187	6	9b58734017ceabe81f490dd0b9f3192bc903d455
ToppCell	COPD-Lymphoid-B_Plasma\|Lymphoid / Disease state, Lineage and Cell class	ARID3A TRIO RALGPS2 RAPGEF1 TEX14 CFAP54	1.21e-04	182	187	6	19db653fe04c5e2957eea1f4893b1c1fca4ddcbd
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TCOF1 LAT2 FCHO2 SIPA1 TGFB1 FCGRT	1.21e-04	182	187	6	16186b7a0c33caa48631962381e3ab7e5d166163
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	DSP RALGPS2 BCL11A DMXL1 DPPA4 PARP12	1.24e-04	183	187	6	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 NSD1 FCHO2 SLF2 PHF3 TLN1	1.28e-04	184	187	6	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	droplet-Mammary_Gland-nan-18m-Lymphocytic-B_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAT2 RALGPS2 BCL11A SIPA1 DMXL1 TGFB1	1.28e-04	184	187	6	73ddf9d647d61381bab1e9c0d983736b6d390c15
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	TACC2 BCL11A CMYA5 TMEM65 GRIP2 PDZD2	1.32e-04	185	187	6	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NCKAP5 BCL11A DCC SCUBE2 VCAN CACNA1G	1.32e-04	185	187	6	1ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCell	droplet-Kidney-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL16 LAT2 BCL11A SIPA1 TGFB1 ARHGEF1	1.36e-04	186	187	6	b2134215eba77aa6ec1babf5c86be1ebd7818caf
ToppCell	droplet-Tongue-nan-24m-Epithelial-suprabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP EVPL PDCD4 TMEM65 PSAPL1 CUX1	1.36e-04	186	187	6	2913b5fd0617d024d600ba7015ec7b1961dade83
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	NCKAP5 TACC2 BCL11A CMYA5 TMEM65 GRIP2	1.40e-04	187	187	6	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PDLIM7 NCKAP5 TACC2 BCL11A NAV2 TSGA10IP	1.44e-04	188	187	6	f54b063025d80de631382bf5326bc40aab7f7d00
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	TACC2 BCL11A CMYA5 TMEM65 GRIP2 PDZD2	1.48e-04	189	187	6	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	droplet-Limb_Muscle-nan-3m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGIP1 TMEM94 C2CD3 SUGP1 FUT2 TRIM37	1.48e-04	189	187	6	16a4c92dd7a0d60f3691bd3130a091a9a54730f1
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCUBE2 ARHGAP31 TLE2 VCAN GRIP2 TOX2	1.48e-04	189	187	6	979b7fa947538aa7ca4a219263da2575869a2caa
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	SYNRG SPR SLF2 PHF3 TLE2 UBE3C	1.52e-04	190	187	6	651a1d3ae286e40f9d9f60e438211c6148d24143
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-immature_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ARHGEF28 POLR1G CEP68 MED19 SCUBE2 FCGRT	1.52e-04	190	187	6	b8693567e26edb830482a60746bf3632a2bf058c
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	IL16 SGIP1 NHSL2 PIEZO2 PDLIM3 VCAN	1.52e-04	190	187	6	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	droplet-Marrow-nan-24m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCOF1 LAT2 SPR LILRA6 PSMB10 FCGRT	1.52e-04	190	187	6	e2fdbfaf08da3274b6bdda615386aa880040a90a
ToppCell	COPD-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	HIVEP1 TRIO TCOF1 RALGPS2 RAPGEF1 BCL11A	1.52e-04	190	187	6	1e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	NCKAP5 TACC2 CMYA5 TMEM65 GRIP2 PDZD2	1.52e-04	190	187	6	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDLIM7 PDLIM3 TLN1 NAV2 TACR2 AHNAK2	1.57e-04	191	187	6	de2cd94ee88a7754f86d39469e38374d668210c7
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IL16 SGIP1 NHSL2 PIEZO2 PDLIM3 NAV2	1.57e-04	191	187	6	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 TCOF1 RALGPS2 BCL11A PDCD4 DMXL1	1.61e-04	192	187	6	2de242d81dc085ae734eb7d1f091af9a542e0866
ToppCell	metastatic_Lymph_Node-Myeloid_cells-CD207+CD1a+_LCs\|Myeloid_cells / Location, Cell class and cell subclass	DSP ADGB NUTM1 KIAA1549L ZFHX4 CACNA1G	1.61e-04	192	187	6	f18da8db573e584c8b90df0814afcf020360108e
ToppCell	moderate-Lymphoid-Treg\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SYNRG IL16 ITGAL UBASH3A TGFB1 ARHGEF1	1.61e-04	192	187	6	e370ff5aaff7b7042ba9aaf93de43aa563b8b9f9
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IL16 SGIP1 NHSL2 PIEZO2 PDLIM3 NAV2	1.61e-04	192	187	6	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCUBE2 ARHGAP31 TLE2 VCAN GRIP2 TOX2	1.61e-04	192	187	6	bd3fa6c8fcb618db64d11f25cabaf08608957c35
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 TCOF1 RALGPS2 BCL11A PDCD4 DMXL1	1.61e-04	192	187	6	ba2a683472a8b785dbf666dc6e94356d879486c3
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDLIM7 IRS1 CMIP PDLIM3 TACR2 AHNAK2	1.66e-04	193	187	6	146e8c148478ab61b1c1dbaf1ee98a8cd4a0ff8a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZDBF2 BCL11A GRIN2B KCNB2 TUB KIAA1549L	1.66e-04	193	187	6	461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZDBF2 BCL11A GRIN2B KCNB2 TUB KIAA1549L	1.66e-04	193	187	6	0dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCell	droplet-Tongue-nan-3m-Epithelial-suprabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF28 DSP PDCD4 TMEM65 PSAPL1 CUX1	1.66e-04	193	187	6	a7002acf3be76b2cc6fc9364176f6b0d3bd27d9c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ASAP1 PIEZO2 EFNB1 ARHGAP31 GRIP2 TOX2	1.66e-04	193	187	6	456aa8a8f1f9cbba0bd618a5f623909079c0f56b
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IL16 SGIP1 NHSL2 PIEZO2 NAV2 TOX2	1.71e-04	194	187	6	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	SGIP1 NHSL2 PDLIM7 PIEZO2 PDLIM3 VCAN	1.71e-04	194	187	6	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PDLIM7 IRS1 TACC2 PDLIM3 AMOTL1 TSGA10IP	1.76e-04	195	187	6	4dba732c8d8ecf0ed9ece1814dc4060402199ed9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ASAP1 PIEZO2 EFNB1 ARHGAP31 GRIP2 TOX2	1.76e-04	195	187	6	23ced69fd904f1d4114b1a7f99f4b5f65ea8824b
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	IL16 SGIP1 NHSL2 PIEZO2 NAV2 TOX2	1.76e-04	195	187	6	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	SGIP1 NHSL2 PIEZO2 PDLIM3 NAV2 TOX2	1.76e-04	195	187	6	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCUBE2 ARHGAP31 TLE2 VCAN GRIP2 TOX2	1.76e-04	195	187	6	98ca9f3aa36211dde1e6f7f3817b9418c95e583e
ToppCell	(0)_NK_cells-(0)_NK_CD160pos\|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	SYNRG LAT2 MBD1 PDCD4 TLN1 TOX2	1.76e-04	195	187	6	6cbeceb52bb207f3c074e57b5b3f7cfb24fd5877
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	IL16 SGIP1 NHSL2 PIEZO2 NAV2 TOX2	1.76e-04	195	187	6	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TACC2 CMYA5 NLGN3 MICALL2 VCAN PDZD2	1.80e-04	196	187	6	f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TACC2 CMYA5 NLGN3 MICALL2 VCAN PDZD2	1.80e-04	196	187	6	671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCell	medial-Hematologic-Interstitial_Macrophage-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LILRB3 LAT2 PDLIM7 LILRA6 VCAN CACNA1G	1.85e-04	197	187	6	b90c8a41e99c87b46be699d03cd49c97a2ad51af
ToppCell	Mild\|World / Condition, Lineage, Cell class and cell subclass	SYNRG IL16 TUT4 PDCD4 PHF3 RSBN1L	1.85e-04	197	187	6	476b0d0389f9fcd4614f6bb1f494281f467f6730
ToppCell	Bronchus_Control_(B.)\|World / Sample group, Lineage and Cell type	HIVEP1 DSP RALGPS2 CMYA5 SHOC1 FUT2	1.85e-04	197	187	6	b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCell	medial-Hematologic-Interstitial_Macrophage\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LILRB3 LAT2 PDLIM7 LILRA6 VCAN CACNA1G	1.85e-04	197	187	6	13aec816e21754eac590a12c3a9c795c41108277
ToppCell	medial-2-Hematologic-Interstitial_Macrophage\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LILRB3 LAT2 PDLIM7 LILRA6 VCAN CACNA1G	1.85e-04	197	187	6	38a74eeb2a4c8d6a86b133f02f4e6c641f16a3ac
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TUT4 TCOF1 ASH1L PSMB10 PHF3 ARHGEF1	1.91e-04	198	187	6	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PDLIM7 IRS1 TACC2 PDLIM3 AMOTL1 TSGA10IP	1.91e-04	198	187	6	2d0c14f8cabab99bc6d7c27685437c78841c7245
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	IL16 SGIP1 NHSL2 PIEZO2 VCAN NAV2	1.91e-04	198	187	6	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	SGIP1 NHSL2 PIEZO2 PDLIM3 VCAN NAV2	1.91e-04	198	187	6	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	NHSL2 RAPGEF1 ASAP1 EFNB1 ARHGAP31 TOX2	1.91e-04	198	187	6	8689090bce9ab6e8f122426a404037e572c6713b
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PDLIM7 IRS1 TACC2 ARHGEF17 PDLIM3 AMOTL1	1.91e-04	198	187	6	c9c96066c7fa897b583657f0b77ea093920ae9ba
ToppCell	control-cDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NCKAP5 BCL11A CTTNBP2NL EFNB1 FCGRT ARHGAP31	1.96e-04	199	187	6	31825ba336603fe940dea6022e18ec25af110f4c
ToppCell	distal-Epithelial-Alveolar_Epithelial_Type_1-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DSP NCKAP5 TACC2 NAV2 LRRN4 PSAPL1	1.96e-04	199	187	6	c1daa481f88d5281b6b5ea8ec8bb70cc0907d613
ToppCell	mild-cDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NCKAP5 BCL11A CTTNBP2NL EFNB1 FCGRT ARHGAP31	2.01e-04	200	187	6	86f585bf9066b179bbcbc703bf43f15da4a07284
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TUT4 TRIO ASH1L NCKAP5 EFNB1 FAM135A	2.01e-04	200	187	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2--L1-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SCUBE2 ARHGAP31 TLE2 VCAN GRIP2 TOX2	2.01e-04	200	187	6	f268cb1bb047e88913a828614b0a77871f5f8814
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SLK ARHGEF28 DSP EVPL HECTD1 AHNAK2	2.01e-04	200	187	6	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IL16 SGIP1 NHSL2 PIEZO2 PDLIM3 VCAN	2.01e-04	200	187	6	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SCUBE2 ARHGAP31 TLE2 VCAN GRIP2 TOX2	2.01e-04	200	187	6	5ff9ac97ef970b3b74ebb07f62a0a1f4176a10b4
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial-Proteoglycan-expressing_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	IL16 ARHGEF28 ARID3A FCGRT NAV2 AJUBA	2.01e-04	200	187	6	aafe594c88710f8c53d59667cdac5035e08f5511
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	IRS1 KCNB2 NLGN3 PDLIM3 ZFHX4 VCAN	2.01e-04	200	187	6	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IL16 SGIP1 NHSL2 PIEZO2 PDLIM3 VCAN	2.01e-04	200	187	6	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IL16 SGIP1 NHSL2 PIEZO2 VCAN NAV2	2.01e-04	200	187	6	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	Tracheal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IL16 SGIP1 NHSL2 PIEZO2 VCAN NAV2	2.01e-04	200	187	6	c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SCUBE2 ARHGAP31 TLE2 VCAN GRIP2 TOX2	2.01e-04	200	187	6	7345cc7dc24b9174541a3e68ecac8c4c092be400
ToppCell	Tracheal-NucSeq-Stromal-Pericyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SGIP1 NHSL2 NCKAP5 ARHGEF17 PHLDB1 PSAPL1	2.01e-04	200	187	6	78cd0b7d221ef855512ee9ac9a291f61622c2e24
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IL16 SGIP1 NHSL2 PIEZO2 PDLIM3 VCAN	2.01e-04	200	187	6	311fab076f2ceb258e3970eb21e39344b894042a
Disease	Intellectual Disability	TRIO SPR TMEM94 ASH1L NSD1 BCL11A GRIN2B DCC TSEN34 CACNA1G PYCR2 PHIP	1.79e-05	447	177	12	C3714756
Disease	Profound Mental Retardation	NSD1 GRIN2B DCC TSEN34 CACNA1G PHIP	1.99e-04	139	177	6	C0020796
Disease	Mental Retardation, Psychosocial	NSD1 GRIN2B DCC TSEN34 CACNA1G PHIP	1.99e-04	139	177	6	C0025363
Disease	Mental deficiency	NSD1 GRIN2B DCC TSEN34 CACNA1G PHIP	1.99e-04	139	177	6	C0917816
Disease	osteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty	ZC3H11B TGFB1 CUX1	2.61e-04	21	177	3	EFO_0004616, EFO_0010726, EFO_1000786
Disease	chronic myeloid leukemia (implicated_via_orthology)	NCSTN SIPA1	3.54e-04	5	177	2	DOID:8552 (implicated_via_orthology)
Disease	waist-hip ratio	ATXN7L1 NSD1 ZC3H11B C11orf24 BCL11A GRIN2B SIM1 SIPA1 KCNB2 BDH1 CMIP SCUBE2 NISCH PKD1 DOT1L PHIP RSBN1L CUX1	4.38e-04	1226	177	18	EFO_0004343
Disease	leukocyte immunoglobulin-like receptor subfamily B member 3 measurement	LILRB3 LILRA6	5.28e-04	6	177	2	EFO_0802705
Disease	peripheral neuropathy, response to bortezomib	DCC CMYA5	5.28e-04	6	177	2	EFO_0003100, EFO_0007808
Disease	leukocyte immunoglobulin-like receptor subfamily A member 6 measurement	LILRB3 LILRA6	5.28e-04	6	177	2	EFO_0801767
Disease	stimulant use measurement	HIVEP1 ASAP1 FAM135A	6.23e-04	28	177	3	EFO_0600076
Disease	insulinoma (is_marker_for)	TGFB1 CUX1	9.78e-04	8	177	2	DOID:3892 (is_marker_for)
Disease	cup-to-disc ratio measurement	RAPGEF1 ZC3H11B ASAP1 KIAA1549L VCAN AMOTL1 NAV2 CUX1 PDZD2	1.21e-03	430	177	9	EFO_0006939
Disease	body fat distribution	NSD1 ZC3H11B MICALL2 RALGPS1 VCAN TSGA10IP	1.42e-03	202	177	6	EFO_0004341
Disease	Disorders of Intracellular Cobalamin Metabolism	MTRR HCFC1	1.56e-03	10	177	2	cv:CN043592
Disease	age at onset, multiple sclerosis	NCKAP5 KCNB2	1.56e-03	10	177	2	EFO_0004847, MONDO_0005301
Disease	smoking behavior, BMI-adjusted waist-hip ratio	NSD1 ZC3H11B CMIP EHMT2	1.81e-03	86	177	4	EFO_0004318, EFO_0007788
Disease	pulse pressure measurement	GDF5-AS1 SGIP1 MBD1 RALGPS2 ZC3H11B HEATR5A SIPA1 TGFB1 CEP68 PIEZO2 MALRD1 KIAA1549L ZFHX4 PKD1 FER DOT1L BAG6 HCFC1	1.85e-03	1392	177	18	EFO_0005763
Disease	brain measurement, neuroimaging measurement	GDF5-AS1 RALGPS2 RABAC1 NCKAP5 DCC RALGPS1 ARHGEF1 VCAN SUGP1 NAV2	1.88e-03	550	177	10	EFO_0004346, EFO_0004464
Disease	Takayasu arteritis	HIVEP1 VWA7 EHMT2 TSEN34 BAG6	2.03e-03	148	177	5	EFO_1001857
Disease	BMI-adjusted waist-hip ratio, sex interaction measurement	ZC3H11B SIM1 CMIP	2.20e-03	43	177	3	EFO_0007788, EFO_0008343
Disease	intracranial aneurysm (is_implicated_in)	VCAN PKD1	2.27e-03	12	177	2	DOID:10941 (is_implicated_in)
Disease	alcohol and nicotine codependence	RGPD2 HIVEP1	2.67e-03	13	177	2	EFO_0004776
Disease	hematologic cancer (implicated_via_orthology)	PIAS3 CUX1	2.67e-03	13	177	2	DOID:2531 (implicated_via_orthology)
Disease	Genetic chronic primary adrenal insufficiency	AIRE UBASH3A	2.67e-03	13	177	2	Orphanet_101960
Disease	Connective Tissue Diseases	PIEZO2 PKD1	2.67e-03	13	177	2	C0009782
Disease	unipolar depression, information processing speed, cognitive function measurement	ADCY10 C16orf82 TRIM37	2.83e-03	47	177	3	EFO_0003761, EFO_0004363, EFO_0008354
Disease	body weight	HIVEP1 C16orf82 MBD1 ZNF280C IRS1 SIM1 DCC KCNB2 POLR1G VIRMA MICALL2 PHF3 PKD1 DOT1L ITIH6 PDZD2	3.95e-03	1261	177	16	EFO_0004338
Disease	Hepatomegaly	KLF11 TGFB1 TRIM37	4.21e-03	54	177	3	C0019209
Disease	susceptibility to common cold measurement	IL16 RALGPS1 FUT2	4.21e-03	54	177	3	EFO_0008417
Disease	reticulocyte count	ARHGEF28 ARID3A ZNF280C ASH1L ZC3H11B IRS1 BCL11A SIPA1 MED19 FCGRT NISCH PKD1 CUX1 PDZD2	4.33e-03	1045	177	14	EFO_0007986
Disease	Sjogren's syndrome (implicated_via_orthology)	AIRE TGFB1	4.59e-03	17	177	2	DOID:12894 (implicated_via_orthology)
Disease	event free survival time, urinary bladder cancer	GRIN2B DCC	5.72e-03	19	177	2	EFO_0000482, MONDO_0001187
Disease	leukemia (implicated_via_orthology)	ASH1L DOT1L	5.72e-03	19	177	2	DOID:1240 (implicated_via_orthology)
Disease	glycoprotein measurement	CMIP SCUBE2 FCGRT SUGP1	5.82e-03	119	177	4	EFO_0004555
Disease	Post-Traumatic Osteoporosis	TGFB1 TLN1 GORAB	5.92e-03	61	177	3	C0751406
Disease	Osteoporosis, Senile	TGFB1 TLN1 GORAB	5.92e-03	61	177	3	C0029459
Disease	Osteoporosis, Age-Related	TGFB1 TLN1 GORAB	5.92e-03	61	177	3	C0001787

Protein segments in the cluster

Peptide	Gene	Start	Entry
SSPRISPATTLRKGD	ARID3B	376	Q8IVW6
SPCSSPVLTKRLLGS	CTTNBP2NL	426	Q9P2B4
PVLTKRLLGSSASSP	CTTNBP2NL	431	Q9P2B4
NKRLASPVAPGALTT	EP400	2651	Q96L91
TITCPLRTPGSLLKD	AMER2	591	Q8N7J2
TETAGSLKVPAPASR	ARHGEF1	756	Q92888
ATPSTLLGSRDPDLK	ASH1L	191	Q9NR48
KLLASATPVSGISLP	CFAP54	2816	Q96N23
SASSKLPPALLTTVG	VCAN	821	P13611
PRGGSLAKVSSSLEP	CEP68	216	Q76N32
GVSSGLLKTRPSLPA	CEP68	581	Q76N32
AKAAGARPLTSPESL	BAG6	1071	P46379
LSRPLSRLPGKTLSA	BDH1	6	Q02338
KLRLIGSSAPLPCLS	ADGB	1081	Q8N7X0
SKLLLAPGSSPKTLS	AIFM3	291	Q96NN9
DASKPSSPRGSLLLD	AJUBA	131	Q96IF1
LTQGSVSDLLARPKP	CUX1	1156	P39880
PASRPKLTSGKLSGI	FCHO2	466	Q0JRZ9
GGPTRLTLPSKSTDA	CMIP	636	Q8IY22
PNSIALPGTSAKRTK	DPPA4	36	Q7L190
GKTDSSSLRPARSVP	AMOTL1	781	Q8IY63
RILLGHATKSFPSSP	EHMT2	106	Q96KQ7
LRSISASKASPPGDL	DFFA	306	O00273
TPSLSAGVSPKRRAL	DOT1L	1096	Q8TEK3
LTSGVRLKNLSPPTS	ADCY10	796	Q96PN6
PFGSPLLSRSVSLLK	C2CD4C	226	Q8TF44
SSSGLHPPKKTLTRS	DMXL1	1271	Q9Y485
KAAQLRPISLPGVSS	EFCAB14	421	O75071
GVSPLSAKLEPSGRT	ATXN7L1	706	Q9ULK2
LTPRGTASPGSQLKA	AIRE	146	O43918
GSTSLLPEQLLSAPK	GORAB	56	Q5T7V8
LDKSIGAASPRPQSL	NSD1	2361	Q96L73
GTRSKSVPELLGTAP	ANKRD33	336	Q7Z3H0
LAPRLSSGALKVATL	RFX5	351	P48382
SSGALKVATLPLSSR	RFX5	356	P48382
LKRAELPGSSSPLLA	ARHGAP39	276	Q9C0H5
SSPRLVSSKEDLAGP	RALGPS1	291	Q5JS13
SRIAGLAVSLTKPSP	NCSTN	116	Q92542
DRGKPPLSSSRSITL	PCDHGB6	426	Q9Y5F9
TIAATDRGKPPLSSS	PCDHGB7	421	Q9Y5F8
DRGKPPLSSSKTITL	PCDHGB7	426	Q9Y5F8
AGRRGASLLSPKSPT	MLX	36	Q9UH92
SKPPSTLLAAGRLSD	ARHGEF28	351	Q8N1W1
ASPGTRPTLKDLTAT	ARHGEF17	526	Q96PE2
LAPLSSKVRLSSPSI	HCFC1	1211	P51610
PSDLSAIATTIKPGL	OSGEPL1	106	Q9H4B0
TASLGLAGKARSPLL	DCC	1381	P43146
KRPKLSSTPPLSALG	INTS1	76	Q8N201
NSLGKSPVATLRIPA	IL31RA	306	Q8NI17
TGEKSPNSPRTLLSL	EIF4E1B	31	A6NMX2
DSGKALAPKISISPR	MTRR	511	Q9UBK8
LLLGSPSSLSPFSKR	BCL11A	621	Q9H165
HLGPTLKPTLATRTA	MBD1	416	Q9UIS9
SLSGRGPTPSLVLSK	MICALL2	431	Q8IY33
GESLTKLRSNLPAPS	FAM135A	726	Q9P2D6
RLKARPSSPGFSVLT	FCGRT	206	P55899
RSGLTVPTSPKGRLL	PDCD4	86	Q53EL6
LSVSSKPPIGRRSSG	PDZD2	2361	O15018
SSSLPPKLLLVSFDG	ENPP4	21	Q9Y6X5
SIGSIISKSPLASPA	EVPL	1791	Q92817
RLSLQPSSGEAAKPL	IL16	861	Q14005
TLQTPAKRPLLAGTT	KDM4D	466	Q6B0I6
VGFPRLASLTLPTKA	LRRC14B	236	A6NHZ5
GSPPATRDLLLSSKV	KIAA1549L	236	Q6ZVL6
ILPSGVSRKPSLLTL	LILRA6	216	Q6PI73
ILPSGVSRKPSLLTL	LILRB3	216	O75022
ARPTRLSLGDPKAST	IRS1	856	P35568
VPLSISRLTPGGKAA	PDLIM7	26	Q9NR12
PVATLSKPSLGDRSK	NUTM1	191	Q86Y26
SKPSVTPSILLALGS	PARP12	681	Q9H0J9
LGSPVLTKLLTASTP	MALRD1	536	Q5VYJ5
SLSPKPTVGRSLCLT	NLGN3	11	Q9NZ94
ISSLTSAVPRPRGKL	ARHGAP33	271	O14559
PSGSRPDTVTLRSAK	ARHGAP33	621	O14559
CTPSPRLALTLKVTG	HECTD1	1811	Q9ULT8
GNSLIAAPLSRSIKP	IL36B	26	Q9NZH7
LLSLLNSSPGPPTRK	HEATR5A	56	Q86XA9
PPGLNRKTSRSTLSL	KCNB2	6	Q92953
SDLSKRPQGLTIKPS	KDM3A	921	Q9Y4C1
KKRGLSDISPSTSLP	C2CD3	16	Q4AC94
SKASASTRPGSLLPA	E2F8	571	A0AVK6
PSPKKDVLSLSGLSS	CACNA1G	2356	O43497
SATTLLPALPKGSRE	DBF4B	426	Q8NFT6
IIRSPKSALGSSALS	FER	431	P16591
VEASLPIALGPKSRS	FRMPD3	1461	Q5JV73
PVLASTSKALGPSQL	FUT2	46	Q10981
LLSPVKPQTLASGAS	CMYA5	2811	Q8N3K9
RLLEAASVSSKGLPS	DSP	2801	P15924
SPRLAESPQLSKGSL	CCDC102A	6	Q96A19
SKGSLLTILGSPSPE	CCDC102A	16	Q96A19
LPLSTGPASRLAAKS	CENPJ	526	Q9HC77
VGPSSSKLPLSGLAE	CEP85	111	Q6P2H3
RAAALSLSTLASPKG	EFNB1	276	P98172
VTSRLRGKAPALSPS	GDF5-AS1	226	Q5U4N7
GRLAEARASTSSPKP	C19orf67	56	A6NJJ6
STSSAKTALGPRVLP	ASAP1	881	Q9ULH1
SNSGTLLPLKPGSLS	ITIH6	731	Q6UXX5
SKLPGSPLILIASSG	KANSL3	266	Q9P2N6
KLNRIASAESPGSPL	KLF11	491	O14901
SRGPRASPTKALLST	KNDC1	251	Q76NI1
ASPTKALLSTPVRNG	KNDC1	256	Q76NI1
LPIRALPFSASSSGK	LINC02913	46	Q8NAJ2
TLLPKGRSALPPSSR	ENPP7	426	Q6UWV6
PLLPRKSGSLSETSD	GRIP2	741	Q9C0E4
KGLLPTSVSPRVSLH	SCUBE2	446	Q9NQ36
PSSPRAKELAVSALG	IPO4	491	Q8TEX9
TGVLRSCGTLTLKPP	IPO4	776	Q8TEX9
GSSLHKLLTLSRTPP	PPRC1	161	Q5VV67
IKGPPVSSLSLASLN	CAMSAP2	1281	Q08AD1
PRLSAPSTKAVIAGI	TACR2	141	P21452
SAVAPGPSALDRKVT	TBRG4	476	Q969Z0
ISAASTPLASKLLGP	LRRN4	471	Q8WUT4
LPSRSSRGSKVSPDV	PKD1	4161	P98161
SLKIEPGTSTPRSAA	RALGPS2	281	Q86X27
SLRSLIEKPPILSSS	MED19	126	A0JLT2
RGDLSLSLALKTGPT	LAT2	161	Q9GZY6
LSSRDPPGSLSAKKV	RSBN1L	31	Q6PCB5
PGTRTGLLKLLSTVS	TSGA10IP	31	Q3SY00
GGILSPLVKDRTSPS	USH2A	4516	O75445
PKPARSSVAGSLSLR	TRIM37	761	O94972
LLLPSLLGATRASPT	PSAPL1	6	Q6NUJ1
LPIPASKRASSDLSI	SLK	331	Q9H2G2
ETPPSRLTGLKRLSS	TEX14	1276	Q8IWB6
PPGCAKTTLVRALAT	SPATA5L1	506	Q9BVQ7
RKLSPFVLSAGSGSP	SYNRG	906	Q9UMZ2
LGDKEISRSSPSPAL	SYNRG	1076	Q9UMZ2
LLSGKSPRKSAEPSA	TCOF1	151	Q13428
PSSGLVTLEKSPALA	NCKAP5	826	O14513
PPSASALLGASIKLT	IGLV4-3	26	A0A075B6K6
PSKIGLLTSGTSRLE	NHSL2	471	Q5HYW2
LLQGLSKLSPSTSGP	MOV10	961	Q9HCE1
LLRPAANVTPTKGSS	RGPD2	881	P0DJD1
PKLREPSKTALGSSL	NAV2	1251	Q8IVL1
DAPTSLPKATRKALG	PTTG3P	51	Q9NZH4
PRSALAPNLLTSGKK	POLR1G	161	O15446
LEGRKSSLPSVAPTG	SH2D6	36	Q7Z4S9
ARLEPLPLTSLKGSA	RNF224	101	P0DH78
LPLTSLKGSAITRQP	RNF224	106	P0DH78
GSRAALPLTKASPES	SIM1	491	P81133
GILFVSSRKHLPTLP	SHOC1	91	Q5VXU9
GSASPKVPRTLLTLD	SIPA1	311	Q96FS4
TPSSPGKLLTRSLAL	PYCR2	301	Q96C36
PLVITRITPGSKAAA	PDLIM3	26	Q53GG5
GAKLLRTLSSPTEPV	PSMB10	221	P40306
TKLPLLSRVPSAGSS	SLF2	471	Q8IX21
LPSRQKTSLLASGAP	ITGAL	411	P20701
TELSPTATPRTLKLG	NFATC2IP	311	Q8NCF5
LVPGAKSSIGLSTIP	AHNAK2	4721	Q8IVF2
SSPKLPVSSLGLAAS	ARID3A	371	Q99856
PKSSALPRTATLATL	C11orf24	196	Q96F05
TPTPSAGKRSLLISR	SUGP1	116	Q8IWZ8
PRKTLGPSDLSLLSL	PIAS3	66	Q9Y6X2
TSAAIPALPGSKGVL	PIAS3	471	Q9Y6X2
TPAPILSGKRKASTA	PRR22	376	Q8IZ63
SPALSLSSAPTKPLL	ZFHX4	3096	Q86UP3
GSPPSIADTLFSRKL	PHIP	141	Q8WWQ0
ALLGPPRALSSLAAK	TMEM143	36	Q96AN5
PRLSPCSSIGKLSKS	RAPGEF1	346	Q13905
PPSALGLSTRKALSV	TMEM94	11	Q12767
GTSVRKTLLLCSPQP	TSEN34	281	Q9BSV6
ASIGNIALSPSPVRK	SGIP1	141	Q9BQI5
KRLLSDSLPPSTGTF	TLN1	1221	Q9Y490
RTLAPLLASLLSPGS	SPR	21	P35270
LTPGRPAAGLSTCKT	TGFB1	21	P01137
RLSSASTGKPPLSVE	ZC3H11A	756	O75152
PPLSRSSVLKSALGP	SREBF2	856	Q12772
GPLRPKTLLLTSSEI	NISCH	1366	Q9Y2I1
SRTDKLGSSILPPLT	PIEZO2	1861	Q9H5I5
GSLRVKSPSKLAVNP	ZDBF2	296	Q9HCK1
SKLTRAPDSPSSVGR	TNFRSF8	206	P28908
SAGSLTSLSLRGKPP	PHF3	1551	Q92576
PSALGSRKLGPRSLS	PPP1R3D	11	O95685
SELSAPTRQKLPALG	TACC2	931	O95359
LLSSKLERPSGGSKP	ARHGAP31	1321	Q2M1Z3
VATLGRSPSPKSALL	PHLDB1	996	Q86UU1
PVTPSLADKLLSRLG	MARS2	526	Q96GW9
DKGISVSLSLPSLPS	TBC1D29P	126	Q9UFV1
LSGTTLLPKLIPSGA	RABAC1	16	Q9UI14
RRLSSASTGKPPLSV	ZC3H11B	756	A0A1B0GTU1
ASRLGLSIPDLTPKQ	TMEM65	181	Q6PI78
SPASLARTLGSKSLL	TOX2	351	Q96NM4
ARTLGSKSLLPGLSA	TOX2	356	Q96NM4
EFIRATPSKPSGLSL	ZNF830	141	Q96NB3
TIRASLGPLQSKLPT	ZNF280C	511	Q8ND82
KSPLALETPNRVSLG	TUT4	616	Q5TAX3
SLASAISGKIPSPLS	TTLL4	196	Q14679
ASSLGSPLPRAKELI	TLE2	276	Q04725
LAPGSKVPLSLRIAS	VWA7	736	Q9Y334
GSIDPPSSLKSRLTG	C16orf82	191	Q7Z2V1
VSKPSAPVFDRLGSL	VIRMA	76	Q69YN4
LGASPRLKVSKPSLS	ZFYVE26	1321	Q68DK2
LGATRPTAPASAKRT	TUB	96	P50607
TSTPSALPTGEKALL	HIVEP1	716	P15822
GLASSPRAPLQSSKA	TBRG1	6	Q3YBR2
KLQRPLTPGSSDSLT	TRIO	511	O75962
SILSAASPGAKLPRV	nan	171	Q6ZQT7
LLKFVTSCSRPPLLG	UBE3C	1011	Q15386
LKSRSSPSLLEPLLA	UBASH3A	16	P57075
AEKSLPLPKSTSGSR	ZBED4	271	O75132
TLKGTPSSSAPLALV	NACA	126	E9PAV3
ASSKPPRISGSLVDT	NDC1	611	Q9BTX1
RSISKKPLDIGLPSS	GRIN2B	1016	Q13224