Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

BRS3 EDNRA OPRL1

4.58e-05133113GO:0008528
GeneOntologyMolecularFunctionpeptide receptor activity

BRS3 EDNRA OPRL1

5.34e-05140113GO:0001653
GeneOntologyMolecularFunctionG protein-coupled receptor activity

BRS3 OR5AK3P CCR5 EDNRA OPRL1

6.21e-05884115GO:0004930
GeneOntologyMolecularFunctionphosphatidylinositol phospholipase C activity

CCR5 EDNRA

8.90e-0526112GO:0004435
GeneOntologyMolecularFunctionphospholipase C activity

CCR5 EDNRA

1.11e-0429112GO:0004629
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

BRS3 OR5AK3P CCR5 EDNRA OPRL1

4.64e-041353115GO:0004888
GeneOntologyMolecularFunctionphosphoric diester hydrolase activity

CCR5 EDNRA

1.25e-0397112GO:0008081
GeneOntologyMolecularFunctionphospholipase activity

CCR5 EDNRA

1.72e-03114112GO:0004620
GeneOntologyMolecularFunctionlipase activity

CCR5 EDNRA

2.50e-03138112GO:0016298
GeneOntologyMolecularFunctionzinc ion binding

TRIM42 RCHY1 ZMYM4

1.12e-02891113GO:0008270
MousePhenoabnormal dorsal aorta morphology

LMO2 EDNRA

6.83e-048172MP:0004787
MousePhenoabnormal avoidance learning behavior

CCR5 OPRL1

9.19e-049472MP:0001462
MousePhenoabnormal artery development

LMO2 EDNRA

1.83e-0313372MP:0003410
MousePhenoabnormal fluid intake

BRS3 CCR5

1.91e-0313672MP:0011947
MousePhenoabnormal drinking behavior

BRS3 CCR5

2.60e-0315972MP:0001422
MousePhenoabnormal spatial learning

CCR5 OPRL1

7.64e-0327672MP:0001463
DomainGPCR_Rhodpsn_7TM

BRS3 CCR5 EDNRA OPRL1

4.43e-04670114IPR017452
Domain7tm_1

BRS3 CCR5 EDNRA OPRL1

4.61e-04677114PF00001
DomainG_PROTEIN_RECEP_F1_1

BRS3 CCR5 EDNRA OPRL1

4.82e-04685114PS00237
DomainG_PROTEIN_RECEP_F1_2

BRS3 CCR5 EDNRA OPRL1

4.98e-04691114PS50262
DomainGPCR_Rhodpsn

BRS3 CCR5 EDNRA OPRL1

5.01e-04692114IPR000276
DomainLIM

LMO2 LIMD2

7.24e-0469112PF00412
Domain-

LMO2 LIMD2

7.45e-04701122.10.110.10
DomainZnf_LIM

LMO2 LIMD2

7.66e-0471112IPR001781
DomainLIM_DOMAIN_1

LMO2 LIMD2

7.66e-0471112PS00478
DomainLIM_DOMAIN_2

LMO2 LIMD2

7.66e-0471112PS50023
DomainLIM

LMO2 LIMD2

7.66e-0471112SM00132
Domain7TM_GPCR_Srsx

BRS3 OPRL1

1.89e-03112112SM01381
Domainzf-C3HC4

TRIM42 RCHY1

7.27e-03223112PF00097
DomainZF_RING_1

TRIM42 RCHY1

1.21e-02291112PS00518
DomainZF_RING_2

TRIM42 RCHY1

1.27e-02298112PS50089
DomainRING

TRIM42 RCHY1

1.33e-02305112SM00184
DomainZnf_RING

TRIM42 RCHY1

1.51e-02326112IPR001841
DomainZnf_RING/FYVE/PHD

TRIM42 RCHY1

2.86e-02459112IPR013083
PathwayWP_GPCRS_PEPTIDE

BRS3 CCR5 EDNRA OPRL1

1.93e-087074MM15959
PathwayWP_PEPTIDE_GPCRS

BRS3 CCR5 EDNRA OPRL1

2.56e-087574M39696
PathwayREACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

BRS3 CCR5 EDNRA OPRL1

1.25e-0619774MM14970
PathwayREACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

BRS3 CCR5 EDNRA OPRL1

1.25e-0619774M12289
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

BRS3 CCR5 EDNRA OPRL1

3.79e-0626074M39397
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

BRS3 CCR5 EDNRA OPRL1

9.76e-0633074M18334
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

BRS3 CCR5 EDNRA OPRL1

1.01e-0533374MM14963
PathwayREACTOME_GPCR_LIGAND_BINDING

BRS3 CCR5 EDNRA OPRL1

2.78e-0543074MM15160
PathwayREACTOME_GPCR_LIGAND_BINDING

BRS3 CCR5 EDNRA OPRL1

3.72e-0546374M507
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

BRS3 CCR5 OPRL1

7.61e-0518673MM15994
PathwayREACTOME_SIGNALING_BY_GPCR

BRS3 CCR5 EDNRA OPRL1

1.37e-0464674MM14962
PathwayREACTOME_SIGNALING_BY_GPCR

BRS3 CCR5 EDNRA OPRL1

1.89e-0470274M746
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

BRS3 EDNRA OPRL1

2.35e-0427273M13380
PathwayWP_GPCRS_OTHER

CCR5 EDNRA

8.85e-049372M39629
PathwayWP_GPCRS_OTHER

EDNRA OPRL1

9.43e-049672MM15939
PathwayWP_GPCRS_ODORANT

BRS3 OPRL1

2.50e-0315772MM15872
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

BRS3 EDNRA

4.42e-0321072MM15043
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

BRS3 EDNRA

4.71e-0321772M18437
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

CCR5 OPRL1

8.22e-0328972MM15057
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

CCR5 OPRL1

9.65e-0331472M600
Pubmed

Association of KIR2DL5B gene with celiac disease supports the susceptibility locus on 19q13.4.

KIR2DL5B KIR2DL5A

1.29e-07213217215859
Pubmed

Some human KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B.

KIR2DL5B KIR2DL5A

1.29e-07213212185535
Pubmed

Gene structure and promoter variation of expressed and nonexpressed variants of the KIR2DL5 gene.

KIR2DL5B KIR2DL5A

1.29e-07213211086080
Pubmed

Promoter variants of KIR2DL5 add to diversity and may impact gene expression.

KIR2DL5B KIR2DL5A

3.87e-07313218461314
Pubmed

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties.

CCR5 EDNRA OPRL1

4.99e-074313323597562
Pubmed

Killer-cell immunoglobulin-like receptors (KIR) in severe A (H1N1) 2009 influenza infections.

KIR2DL5B KIR2DL5A

7.74e-07413222652695
Pubmed

KIR2DL5, a novel killer-cell receptor with a D0-D2 configuration of Ig-like domains.

KIR2DL5B KIR2DL5A

7.74e-07413210820258
Pubmed

Investigation of killer cell immunoglobulin-like receptor (KIR) gene diversity: KIR2DL2, KIR2DL5 and KIR2DS5.

KIR2DL5B KIR2DL5A

7.74e-07413218498296
Pubmed

Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.

KIR2DL5B KIR2DL5A

1.00e-051313219120281
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptors gene family in Zhejiang Han population].

KIR2DL5B KIR2DL5A

1.54e-051613216403292
Pubmed

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.

KIR2DL5B KIR2DL5A

1.75e-051713220878400
Pubmed

[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].

KIR2DL5B KIR2DL5A

1.75e-051713219218127
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.

KIR2DL5B KIR2DL5A

1.75e-051713220650299
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.

KIR2DL5B KIR2DL5A

1.75e-051713219450876
Pubmed

Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.

KIR2DL5B KIR2DL5A

1.75e-051713219761533
Pubmed

Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes.

KIR2DL5B KIR2DL5A

1.97e-051813220200544
Pubmed

HLA and KIR frequencies in Sicilian Centenarians.

KIR2DL5B KIR2DL5A

2.44e-052013220426625
Pubmed

Compound KIR-HLA genotype analyses in the Iranian population by a novel PCR-SSP assay.

KIR2DL5B KIR2DL5A

2.44e-052013220193031
Pubmed

Distribution of KIR genes in the population of unrelated individuals homozygous for ancestral haplotype AH8.1 (HLA-A1B8DR3).

KIR2DL5B KIR2DL5A

2.97e-052213220492596
Pubmed

Dissociation of heterotrimeric g proteins in cells.

CCR5 EDNRA OPRL1

3.69e-0517913318577758
Pubmed

Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.

KIR2DL5B KIR2DL5A

7.62e-053513219683555
Pubmed

Multi-locus interactions predict risk for post-PTCA restenosis: an approach to the genetic analysis of common complex disease.

CCR5 EDNRA

2.26e-046013212082592
Pubmed

Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.

CCR5 OPRL1

3.52e-04751322834384
Cytoband19p13.3

KIR2DL5B KIR2DL5A

1.99e-0323713219p13.3
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR2DL5B KIR2DL5A

6.14e-0518122620
GeneFamilyLIM domain containing

LMO2 LIMD2

6.77e-04591221218
GeneFamilyRing finger proteins

TRIM42 RCHY1

1.38e-0227512258
GeneFamilyADAM metallopeptidase domain containing|CD molecules

KIR2DL5A CCR5

2.71e-02394122471
CoexpressionGSE22886_NAIVE_VS_IGM_MEMORY_BCELL_UP

LMO2 KIR2DL5A EDNRA

8.75e-05197123M4434
CoexpressionGSE20715_0H_VS_24H_OZONE_LUNG_UP

LMO2 LIMD2 ZMYM4

9.15e-05200123M4366
CoexpressionGSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_DN

LMO2 LIMD2 ZMYM4

9.15e-05200123M8997
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2 CCR5

6.57e-061731037456a417c5c1d4ba25f9489065aae322421308a6
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2 CCR5

6.57e-0617310335586a9e5f15b41609b6224e33eb3aa3cb7e03b7
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2 CCR5

6.57e-06173103cd635751f999e12b14c0accfa1c4c1fd3c1d4540
ToppCellmetastatic_Lymph_Node-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

LMO2 LIMD2 CCR5

9.55e-06196103e1a9198bc51e01308f066323c5e089cfaf04b2ca
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-C1ql2-Excitatory_Neuron.Slc17a7.C1ql2-Cck_(Dentate_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

LIMD2 BRS3

3.62e-0412910208ecebb7f09d105dfdfd2191fc310910d3baec0f
ToppCellLymphoid-NK_cells|World / shred on cell class and cell subclass (v4)

BRS3 CCR5

3.73e-04131102b0b62392d1637601115e85f5584fdcd5dbd0c778
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

LIMD2 CCR5

4.38e-04142102d60d2a5d0876a552bc161fc4e2dfe180f88f03a5
ToppCellLymphoid-Lymphoid-NK_cells|Lymphoid / shred on cell class and cell subclass (v4)

BRS3 CCR5

4.75e-04148102d51a4b654a88d58dcdf29c2bc362c0cc1c40723a
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related|GW10 / Sample Type, Dataset, Time_group, and Cell type.

LMO2 EDNRA

4.95e-04151102edb2f59789c295838d2030b80c792cbea25eaa3d
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related-Oligodendrocyte/OPC|GW10 / Sample Type, Dataset, Time_group, and Cell type.

LMO2 EDNRA

4.95e-041511024533bccc996395f74b16af939ce79b6fe253c073
ToppCellPSB-critical-LOC-Lymphoid-NKT|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LIMD2 CCR5

5.08e-041531024d45aa5e3710d5badc13940f14095c1894dbab9d
ToppCellHealthy_Control-Myeloid-Macrophages-FCN1_high|Healthy_Control / Condition, Lineage, Cell class and cell subclass

LMO2 LIMD2

5.21e-04155102cd2ccb4632713b4def3a1064599b78207e2e44c0
ToppCelltumor_Lung-B_lymphocytes-GC_B_cells_in_the_LZ|tumor_Lung / Location, Cell class and cell subclass

LMO2 LIMD2

5.28e-04156102b5851474ba14dd2b4867415828b52dd98ecdd6d3
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LMO2 LIMD2

5.28e-04156102203ef22eb76bd2b829b027c30af0557080f4006c
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LIMD2 CCR5

5.28e-04156102fbe23876f0899853cea3c5c4f3044a9cea064d5b
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LMO2 CCR5

5.41e-04158102216b3f482daa2d0d7fcaf5a8559e3ccbdb8e110d
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LMO2 CCR5

5.41e-041581029712bb8b1bacb8a38c99a22bc2babec5d5160e2a
ToppCellcellseq2-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-Treg|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LIMD2 CCR5

5.48e-04159102048b6a97568242c8846034277680632e5de75840
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2

5.62e-041611029edcab51da01a84cfe6166ed4c1f951a4ceeac55
ToppCellImmune_cells-NK_cells|World / Lineage and Cell class

LIMD2 CCR5

5.62e-041611023ef2e15b06286d94c18b71626aed456f681cc77b
ToppCellfacs-Large_Intestine-Proximal-24m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2

5.62e-04161102cb4921da94b3355d5234b389aa3ec15939607cd5
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_P4HA3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRIM42 EDNRA

5.69e-04162102dd4a08af653095ad4f63112312715589a1d43b38
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 CCR5

5.69e-0416210258fe827198c172eeaa26273b0fad7991a718b0bf
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 CCR5

5.76e-04163102d18fee517e0daed51f89703f94f218567c83cb03
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45____NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 CCR5

5.76e-04163102f4a6e28ad3c1fcbf62ed9b2bf09f65d2ab0b31d1
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 BRS3

5.83e-041641027c016236f0cea38195c1373ebbd2c0b2b2ec81ad
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 BRS3

5.83e-0416410207d9252b267cb61c6050fbfa5b440aef1349f673
ToppCellnormal_Lymph_Node-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

LIMD2 CCR5

6.04e-04167102820472887f43b42ae7e44513ca3d5465fb4f71a7
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LMO2 LIMD2

6.12e-0416810208eb1284f9b8bd3e0e4b21bfc2bbee01d35a0bd7
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 CCR5

6.12e-041681021fabb2455ce15315f19f01ea9308bc9e453cc095
ToppCell5'-Adult-SmallIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LMO2 LIMD2

6.19e-04169102a34aff9257ae9746226ee7af595c4678a4b0c896
ToppCellfacs-Pancreas-Endocrine-18m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 CCR5

6.19e-04169102c68a305069a149d66dfdeef2a8010f460dc1da3b
ToppCellfacs-Pancreas-Endocrine-18m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 CCR5

6.19e-041691020e3d0b71fc21fd1de7034d13895608de5494fad8
ToppCellfacs-Pancreas-Endocrine-18m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 CCR5

6.19e-0416910280089dfb1f0f4d6bdf6ca161e902b38011992dfd
ToppCellMonocytes-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

LMO2 LIMD2

6.26e-041701024e93b66b3033e6e4d5f6d2f41974623a53108f5e
ToppCelldroplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LIMD2 CCR5

6.33e-04171102834b39b48bf3135dc41e787f5e20ebb234b5d97a
ToppCelldroplet-Limb_Muscle-nan-18m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 CCR5

6.33e-041711024198e7fef1aaee3d85722094f3e444655d393e9e
ToppCelldroplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LIMD2 CCR5

6.41e-04172102fdf54ab7ec002d831d8cce2ce5956d644176ca00
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EDNRA CLUL1

6.41e-0417210280b565f6e37f38629f4cf89d5b053b3b8517244e
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 CCR5

6.41e-04172102adf016e5856bc85e7bed58aee09ade483b9dcb00
ToppCelldroplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LIMD2 CCR5

6.41e-04172102a749f4ab4048d806a83f1f71a197584b8db833ad
ToppCell5'-Adult-LargeIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LMO2 LIMD2

6.48e-04173102b7e0193fd4983cb38d1bee441f608f73ee8743b9
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 CCR5

6.56e-04174102785be49a2dbbb1dff0fbced1b48b942c2f4a508d
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-CD8+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 CCR5

6.56e-04174102986e591d3d46009e53548dfa1f2126cf31063ef4
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LMO2 LIMD2

6.56e-04174102fde40c5d51f5380088360dc5a583eb04e518deb6
ToppCelldroplet-Heart-HEART-1m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 CCR5

6.63e-04175102a2fed97cf8d28f9936fe791e5e8c43d2430330c9
ToppCelldroplet-Heart-HEART-1m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 CCR5

6.63e-0417510243b9cfd7c47d57244565c641e57f3256b5900804
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2

6.71e-04176102e29a13b8152ee84ca82fd1158d96d3f112e3cde3
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LIMD2 CCR5

6.71e-04176102dca70f309af24421f8dc708cbd88512814b8e79e
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2

6.71e-0417610200510bf8ede0945dfcbd58cc8f34fddf914b6e49
ToppCelldroplet-Heart-HEART-1m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 CCR5

6.71e-041761021df640f88667e2dad30e65279d6d33bba75024c1
ToppCellfacs-Trachea-3m-Hematologic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LIMD2 CCR5

6.78e-04177102c9d235fc518b291ed98088a1206d14d6692bc7fd
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LIMD2 CCR5

6.78e-04177102d6b7d387e7485ff52ce27f51df8b8050f49fd941
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 CCR5

6.86e-0417810293bd3205081b97e00e7a1bbaf4a311075b9cbfe8
ToppCellBAL-Control-Myeloid-MoAM-MoAM2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LIMD2 CCR5

6.94e-041791022fca4117c58824562ec80c7713fe15689a28efb3
ToppCellBAL-Control-Myeloid-MoAM-MoAM2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LIMD2 CCR5

6.94e-04179102898425fa81526a2e00fca7a25085229ff1f31069
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR-_ILC3|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LIMD2 CCR5

7.01e-041801023f0a692ad2823951e0ec23d0452f436c5f5c09c0
ToppCellfacs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EDNRA OPRL1

7.01e-0418010263a6d532b16b8b15c7c9102148d7297ee3afd641
ToppCellfacs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EDNRA OPRL1

7.01e-04180102a37cc885fe3f6cb9df69d43358064c83c18412e7
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EDNRA OPRL1

7.09e-04181102395cf5aa2d89b05328ab516b8c89401020b6d830
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EDNRA OPRL1

7.09e-04181102429df38438d5a7ff490c9ede34b69e2970c7ded2
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-CD45____T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 CCR5

7.09e-04181102e8a68214930a6d15c47207656601b2209e283aae
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2

7.09e-04181102852115eff9a68a6f657aada2386ee4a1e50a4d5b
ToppCellmetastatic_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_LZ|metastatic_Lymph_Node / Location, Cell class and cell subclass

LMO2 LIMD2

7.25e-0418310230db83f600e2c4ad3af68a8a946673f4352a2807
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LIMD2 CCR5

7.25e-04183102d1bf3abf42eb9d7facf775becf1338d1faadd647
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 CCR5

7.25e-0418310282b84ee065fb573688d59da97a327152a1ba294c
ToppCelldroplet-Mammary_Gland-nan-21m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2

7.25e-04183102e7038532a6e159bb3e383cdd9c44b3b7f21c0c01
ToppCellfacs-Brain_Non-Myeloid-Striatum_|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 CCR5

7.25e-04183102824ecda1219fb596a01bf5cfeee29a6daa462098
ToppCellHSPCs-LMPPs|HSPCs / Lineage and Cell class

LMO2 LIMD2

7.25e-04183102f7392645d38da7285e797aa0e4625751af83ebd7
ToppCellHSPCs-LMPPs|World / Lineage and Cell class

LMO2 LIMD2

7.25e-04183102e401f06843528a75693ce455bbeff2a98b8c24e5
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LIMD2 CCR5

7.25e-04183102bd78e5c2670e67b4363078e3ca5a5b7081d24b7e
ToppCelldroplet-Mammary_Gland-nan-3m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2

7.41e-041851023d035bb453a5942411da4eb8b3a1ca0961a089b2
ToppCellfacs-Brain_Myeloid-Hippocampus_-18m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2

7.48e-04186102f3345fad9559ec222062a6f516b9d3f815d98acf
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2

7.48e-041861026b2d15e2756d4d4d68ad600e4a6c074edc3488f2
ToppCellfacs-Brain_Myeloid-Hippocampus_-18m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2

7.48e-0418610206e6e805f90d92c870f36b79fa0749988a4595bb
ToppCellfacs-Brain_Myeloid-Hippocampus_-18m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2

7.48e-0418610277baa0075e53ccb654a561e3289eba41deab8561
ToppCellControl-Myeloid-MoAM3,_VCAN|Myeloid / Condition, Lineage and Cell class

LIMD2 CCR5

7.48e-041861020bf16ac48931b62bb3c33d63ff4279654148e293
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-Treg|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LIMD2 CCR5

7.48e-041861022a9daf96c2a47f1ed5421130f32f17bd33e644a7
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2

7.48e-04186102a8fcb440d88770f95678c5d28413fc4d847f42a8
ToppCellfacs-Brain_Myeloid-Hippocampus_|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2

7.48e-04186102eb1d1941cd6e4d9f0655aff3ba8df3c29c06b3a2
ToppCellfacs-Brain_Myeloid-Hippocampus_-18m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2

7.48e-0418610228699e3574d3a183190bdb6c5db2219167d41579
ToppCelldroplet-Mammary_Gland-nan-21m-Lymphocytic-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 LIMD2

7.56e-0418710216b2fddf2c23a29f173102f117876c9df5544ae4
ToppCellCOVID_non-vent-Myeloid-Dendritic-cDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

LMO2 CCR5

7.56e-0418710255fe4e8b4f301876716c1af15c34d42164f2358e
ToppCellCOVID_non-vent-Myeloid-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

LMO2 CCR5

7.56e-04187102936aaca144b79a809617cbe3058bf434a4b3d46a
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO2 OPRL1

7.56e-041871022c145e9d11424939dd99012a8cedf5d998b966e9
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EDNRA OPRL1

7.56e-04187102dba4924d914a7dcd4901142684ba920c2404860b
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EDNRA OPRL1

7.56e-041871029688141beef4f62613d7a810c5872ccb9afc1a71
ToppCellnormal_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_LZ|B_lymphocytes / Location, Cell class and cell subclass

LMO2 LIMD2

7.56e-04187102457eb3791a8c5458d81833e0701ac5a9bfdee2bf
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-B_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LMO2 LIMD2

7.65e-041881027c542b226240adcb7797be0ded6523e5732f0078
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-B_cell-B_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LMO2 LIMD2

7.65e-041881029526d9e035eadbb0dcd4ad6e79a3a2b7f7845d74
ToppCellmetastatic_Lymph_Node-B_lymphocytes-Undetermined|metastatic_Lymph_Node / Location, Cell class and cell subclass

LMO2 LIMD2

7.65e-041881020ddc5dbe2fd905fee20c33d9845629e259faacd9
ToppCell3'-Airway_Nasal-Immune_Lymphocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LIMD2 CCR5

7.73e-041891022424e4dc9e8c7f5b3b31272405c6c1d4c8af6d9e
ToppCellBAL-Control-Myeloid-MoAM-MoAM1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LIMD2 CCR5

7.73e-04189102ebb5e069fdca7cf8ffac16a57572e92d2593c86a
ToppCellControl-Myeloid-MoAM1|Control / Disease group,lineage and cell class (2021.01.30)

LIMD2 CCR5

7.73e-0418910255d5c2fb9e6ab556d42c83a1e985ee66e4cf9dba
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LIMD2 CCR5

7.73e-04189102a010f3e4da6e9bb23b0b9a7f82ad5cee4e607ecd
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 CCR5

7.73e-0418910243d8264b763ef6c82368c1d67d63ff0a25861c45
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LIMD2 CCR5

7.73e-04189102637f26503e4bd7b4e5642ec1a722ffabcda4fac7
ToppCellBAL-Control-Myeloid-MoAM-MoAM1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LIMD2 CCR5

7.73e-04189102a59e4eaff430a443f9fa7edabe64e66a15b6bffb
ToppCelltumor_Lung-B_lymphocytes-GC_B_cells_in_the_LZ|B_lymphocytes / Location, Cell class and cell subclass

LMO2 LIMD2

7.81e-04190102bfb16efb23add53eebabc8e48f20c96994ec01da
ToppCell10x5'-GI_large-bowel-Lymphocytic_B-GC_B_(II)|GI_large-bowel / Manually curated celltypes from each tissue

LMO2 LIMD2

7.81e-04190102fee64bacbb330d04dc1dc63909838f2c605d9f1f
ComputationalGenes in the cancer module 134.

CCR5 EDNRA

2.68e-043092MODULE_134
ComputationalGenes in the cancer module 288.

CCR5 EDNRA

4.09e-043792MODULE_288
ComputationalGPCR signaling pathways (immune and neuro).

CCR5 EDNRA

2.40e-039092MODULE_375
ComputationalGenes in the cancer module 27.

BRS3 CCR5 EDNRA

2.59e-0335593MODULE_27
ComputationalGenes in the cancer module 128.

LMO2 CCR5

2.78e-039792MODULE_128
ComputationalGenes in the cancer module 79.

LMO2 CCR5

2.90e-039992MODULE_79
ComputationalImmune response.

LMO2 CCR5

2.96e-0310092MODULE_170
ComputationalGenes in the cancer module 146.

CCR5 EDNRA

3.07e-0310292MODULE_146
ComputationalGenes in the cancer module 289.

CCR5 EDNRA

4.51e-0312492MODULE_289
DrugFoliosidine [2520-38-9]; Up 200; 13uM; PC3; HT_HG-U133A

LMO2 RCHY1 EDNRA OPRL1

3.81e-061991344295_UP
Drugpiperidine

BRS3 CCR5 OPRL1

4.99e-05130133CID000008082
DrugS-oxide

CCR5 EDNRA

1.39e-0431132CID011949597
Drugrosiglitazone; Up 200; 10uM; HL60; HT_HG-U133A

BRS3 EDNRA OPRL1

1.74e-041981336192_UP
DrugMyosmine [532-12-7]; Up 200; 27.4uM; HL60; HT_HG-U133A

LIMD2 BRS3 EDNRA

1.76e-041991332199_UP
DrugMidodrine hydrochloride [3092-17-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A

LMO2 RCHY1 EDNRA

1.76e-041991336804_DN
DrugSR140333

EDNRA OPRL1

3.21e-0447132CID000108166
Drugnalmefene HCl

EDNRA OPRL1

3.93e-0452132CID000004422
DrugAC1L1KRB

EDNRA OPRL1

4.24e-0454132CID000005621
DrugAC1LAJDX

EDNRA OPRL1

5.76e-0463132CID000469496
DrugAC1L1KS5

BRS3 EDNRA OPRL1

8.02e-04334133CID000005631
Drugthiorphan

EDNRA OPRL1

1.12e-0388132CID000003132
Drug2-Naphthylamine

CCR5 EDNRA

1.28e-0394132ctd:D015081
Drugmeclofenamate

EDNRA OPRL1

1.28e-0394132CID000004036
Drugnitrendipine

BRS3 EDNRA

1.39e-0398132CID000004507
DrugDinoprost

CCR5 EDNRA

2.17e-03123132ctd:D015237
DrugMonocrotaline

LIMD2 EDNRA

2.21e-03124132ctd:D016686
DiseaseAntithrombotic agent use measurement

EDNRA OPRL1

1.52e-0455102EFO_0009925
Diseasesciatic neuropathy (biomarker_via_orthology)

RCHY1 OPRL1

4.93e-0499102DOID:11446 (biomarker_via_orthology)
Diseasehypertension (is_implicated_in)

CCR5 EDNRA

7.35e-04121102DOID:10763 (is_implicated_in)
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

CCR5 EDNRA

1.08e-03147102DOID:9352 (biomarker_via_orthology)
DiseaseDisease Exacerbation

RCHY1 EDNRA

1.36e-03165102C0235874
Diseasehypertension (biomarker_via_orthology)

CCR5 EDNRA

2.55e-03227102DOID:10763 (biomarker_via_orthology)
DiseaseMalignant neoplasm of breast

LIMD2 EDNRA CLUL1

4.76e-031074103C0006142

Protein segments in the cluster

PeptideGeneStartEntry
FVSKKFKNCFQSCLC

EDNRA

371

P25101
FFQKHIAKRFCKCCS

CCR5

311

P51681
HLECFKCAACQKHFC

LMO2

116

P25791
FFFLLHCCCSNKKNA

KIR2DL5A

256

Q8N109
DKLIFHNSCFCCKHC

LIMD2

56

Q9BT23
FFFLLHCCCSNKKNA

KIR2DL5B

256

Q8NHK3
LSFCKSNKINHFFCD

OR5AK3P

166

Q8NH89
FLDENFKACFRKFCC

OPRL1

321

P41146
NKLLCTFCKFSFHNG

TRIM42

306

Q8IWZ5
SFQKHFKAQLFCCKA

BRS3

336

P32247
NLSRCFKFHEKCQKC

CLUL1

311

Q15846
FFHCLKCNLCLAMNL

RCHY1

116

Q96PM5
KHFCNLLCILMFCNQ

ZMYM4

836

Q5VZL5