Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of postsynaptic actin cytoskeleton	POTEF ACTB ACTG1 POTEE POTEI	1.81e-09	11	107	5	GO:0098973
GeneOntologyMolecularFunction	structural constituent of postsynapse	POTEF ACTB ACTG1 POTEE POTEI	7.22e-07	32	107	5	GO:0099186
GeneOntologyMolecularFunction	structural constituent of synapse	POTEF ACTB ACTG1 POTEE POTEI	2.92e-06	42	107	5	GO:0098918
GeneOntologyMolecularFunction	structural constituent of cytoskeleton	POTEF ACTB ACTG1 POTEE TLN1 POTEI	7.16e-05	130	107	6	GO:0005200
GeneOntologyMolecularFunction	disaccharide binding	LGALS9C LGALS1	5.87e-04	7	107	2	GO:0048030
GeneOntologyBiologicalProcess	postsynaptic actin cytoskeleton organization	POTEF ACTB ACTG1 POTEE POTEI	5.72e-07	31	109	5	GO:0098974
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	LGALS9C SDK2 PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2 DAB1 CLSTN2 LGALS1 CDH24 CX3CL1	8.44e-07	313	109	11	GO:0098742
GeneOntologyBiologicalProcess	postsynaptic cytoskeleton organization	POTEF ACTB ACTG1 POTEE POTEI	1.08e-06	35	109	5	GO:0099188
GeneOntologyBiologicalProcess	maintenance of protein location	LGALS9C CCDC22 LGALS1 HNRNPU PFN4 ANKRD13C TACC3	2.18e-06	112	109	7	GO:0045185
GeneOntologyBiologicalProcess	cell-cell adhesion	LGALS9C SDK2 PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2 ICAM3 ACTB DAB1 ACTG1 TSC2 CLSTN2 ADGRV1 LGALS1 CDH24 TLN1 CTSG CX3CL1	1.33e-05	1077	109	18	GO:0098609
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	SDK2 PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2 CLSTN2 CDH24	6.15e-05	187	109	7	GO:0007156
GeneOntologyBiologicalProcess	synapse organization	DAB2IP SDK2 POTEF ACTB DAB1 ACTG1 TSC2 CLSTN2 DCTN1 POTEE POTEI CX3CL1 PICK1	6.67e-05	685	109	13	GO:0050808
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	SEMA6B PLXNA3 POTEF TPRN ACTB DAB1 ACTG1 TSC2 POTEE PTPRQ POTEI TBR1 LGI1	1.60e-04	748	109	13	GO:0048667
GeneOntologyBiologicalProcess	regulation of transepithelial transport	ACTB ACTG1	1.65e-04	4	109	2	GO:0150111
GeneOntologyBiologicalProcess	cell morphogenesis	DAB2IP SEMA6B PLXNA3 POTEF TPRN ACTB DAB1 ACTG1 TSC2 SIPA1 KIF20B POTEE CDH24 PTPRQ POTEI TBR1 LGI1	1.71e-04	1194	109	17	GO:0000902
GeneOntologyBiologicalProcess	cell junction organization	DAB2IP SDK2 POTEF ACTB DAB1 ACTG1 TSC2 CLSTN2 DCTN1 POTEE CDH24 TLN1 POTEI CX3CL1 PICK1	1.85e-04	974	109	15	GO:0034330
GeneOntologyBiologicalProcess	axonogenesis	SEMA6B PLXNA3 POTEF ACTB DAB1 ACTG1 TSC2 POTEE POTEI TBR1 LGI1	2.04e-04	566	109	11	GO:0007409
GeneOntologyBiologicalProcess	neuron development	DAB2IP SEMA6B PLXNA3 POTEF TPRN ACTB DAB1 ACTG1 TSC2 ADGRV1 KIF20B LGALS1 POTEE PTPRQ POTEI TBR1 CX3CL1 PICK1 LGI1	2.24e-04	1463	109	19	GO:0048666
GeneOntologyBiologicalProcess	maintenance of location	LGALS9C CCDC22 LGALS1 HNRNPU LIME1 PFN4 ANKRD13C TACC3 CX3CL1	2.55e-04	396	109	9	GO:0051235
GeneOntologyBiologicalProcess	neuron projection morphogenesis	DAB2IP SEMA6B PLXNA3 POTEF ACTB DAB1 ACTG1 TSC2 KIF20B POTEE POTEI TBR1 LGI1	3.15e-04	802	109	13	GO:0048812
GeneOntologyCellularComponent	NuA4 histone acetyltransferase complex	POTEF ACTB ACTG1 POTEE POTEI	6.04e-07	32	108	5	GO:0035267
GeneOntologyCellularComponent	H4/H2A histone acetyltransferase complex	POTEF ACTB ACTG1 POTEE POTEI	6.04e-07	32	108	5	GO:0043189
GeneOntologyCellularComponent	H4 histone acetyltransferase complex	POTEF ACTB ACTG1 POTEE POTEI	3.48e-06	45	108	5	GO:1902562
GeneOntologyCellularComponent	RAVE complex	DMXL2 DMXL1	7.91e-05	3	108	2	GO:0043291
GeneOntologyCellularComponent	blood microparticle	POTEF ACTB ACTG1 POTEE C4A C4B	1.03e-04	144	108	6	GO:0072562
GeneOntologyCellularComponent	actin filament	POTEF ACTB ACTG1 POTEE MICAL2 POTEI	1.12e-04	146	108	6	GO:0005884
GeneOntologyCellularComponent	histone acetyltransferase complex	POTEF ACTB ACTG1 POTEE POTEI	1.28e-04	94	108	5	GO:0000123
GeneOntologyCellularComponent	protein acetyltransferase complex	POTEF ACTB ACTG1 POTEE POTEI	2.05e-04	104	108	5	GO:0031248
GeneOntologyCellularComponent	acetyltransferase complex	POTEF ACTB ACTG1 POTEE POTEI	2.56e-04	109	108	5	GO:1902493
GeneOntologyCellularComponent	dense body	ACTB ACTG1	5.46e-04	7	108	2	GO:0097433
GeneOntologyCellularComponent	axon	DAB2IP POTEF ACTB ACTG1 TSC2 DCTN1 KIF20B POTEE C4A C4B POTEI GABBR1 LGI1	6.85e-04	891	108	13	GO:0030424
GeneOntologyCellularComponent	symbiont cell surface	C4A C4B	7.26e-04	8	108	2	GO:0106139
GeneOntologyCellularComponent	stereocilium base	TPRN PTPRQ	7.26e-04	8	108	2	GO:0120044
GeneOntologyCellularComponent	other organism part	C4A C4B	9.30e-04	9	108	2	GO:0044217
GeneOntologyCellularComponent	cluster of actin-based cell projections	TPRN ACTB DAB1 ADGRV1 NPC1L1 PTPRQ	1.07e-03	223	108	6	GO:0098862
HumanPheno	Subcortical cerebral atrophy	MAN2B1 ACTB ACTG1 POGZ ADGRV1	1.10e-06	27	37	5	HP:0012157
MousePheno	decreased cochlear hair cell stereocilia number	TPRN ACTB ACTG1 ADGRV1 PTPRQ	4.66e-07	26	86	5	MP:0004523
MousePheno	decreased outer hair cell stereocilia number	TPRN ACTB ACTG1 ADGRV1	3.83e-06	18	86	4	MP:0004529
MousePheno	increased susceptibility to age-related hearing loss	ACTB ACTG1 ADGRV1 PTPRQ	1.08e-05	23	86	4	MP:0004748
MousePheno	abnormal outer hair cell stereociliary bundle morphology	TPRN ACTB ACTG1 ADGRV1 PTPRQ	6.02e-05	68	86	5	MP:0004527
MousePheno	abnormal susceptibility to hearing loss	ACTB ACTG1 ADGRV1 PTPRQ	8.40e-05	38	86	4	MP:0006334
MousePheno	cryptophthalmos	FRAS1 FREM2	1.12e-04	3	86	2	MP:0005242
MousePheno	fetal bleb	FRAS1 FREM2	2.23e-04	4	86	2	MP:0008856
MousePheno	abnormal cochlear hair cell stereociliary bundle morphology	TPRN ACTB ACTG1 ADGRV1 PTPRQ	2.41e-04	91	86	5	MP:0004521
MousePheno	decreased spleen germinal center size	C4A C4B ABCC10	3.18e-04	22	86	3	MP:0008484
MousePheno	audiogenic seizures	ADGRV1 GABBR1 LGI1	3.18e-04	22	86	3	MP:0001496
MousePheno	abnormal somatic sensory system morphology	MAN2B1 TPRN ACTB DAB1 ACTG1 ADGRV1 NXNL2 LGALS1 RHO PTPRQ NOTO TBR1 GABBR1	3.39e-04	702	86	13	MP:0000959
MousePheno	short outer hair cell stereocilia	ACTB PTPRQ	3.70e-04	5	86	2	MP:0004531
MousePheno	abnormal outer hair cell stereocilia length	ACTB PTPRQ	3.70e-04	5	86	2	MP:0014411
Domain	Actin_CS	POTEF ACTB ACTG1 POTEE POTEI	2.23e-08	16	106	5	IPR004001
Domain	ACTINS_2	POTEF ACTB ACTG1 POTEE POTEI	3.14e-08	17	106	5	PS00432
Domain	Actin/actin-like_CS	POTEF ACTB ACTG1 POTEE POTEI	4.33e-08	18	106	5	IPR020902
Domain	ACTINS_ACT_LIKE	POTEF ACTB ACTG1 POTEE POTEI	5.84e-08	19	106	5	PS01132
Domain	Actin	POTEF ACTB ACTG1 POTEE POTEI	8.09e-07	31	106	5	IPR004000
Domain	Actin	POTEF ACTB ACTG1 POTEE POTEI	8.09e-07	31	106	5	PF00022
Domain	ACTIN	POTEF ACTB ACTG1 POTEE POTEI	8.09e-07	31	106	5	SM00268
Domain	CA	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2 CLSTN2 FREM2 CDH24	4.12e-06	115	106	7	SM00112
Domain	Cadherin	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2 CLSTN2 FREM2 CDH24	4.88e-06	118	106	7	IPR002126
Domain	MacrogloblnA2_thiol-ester-bond	CD109 C4A C4B	9.75e-06	8	106	3	IPR019565
Domain	Calx_beta	FRAS1 ADGRV1 FREM2	9.75e-06	8	106	3	SM00237
Domain	Thiol-ester_cl	CD109 C4A C4B	9.75e-06	8	106	3	PF10569
Domain	MacrogloblnA2_CS	CD109 C4A C4B	9.75e-06	8	106	3	IPR019742
Domain	Calx_beta	FRAS1 ADGRV1 FREM2	1.46e-05	9	106	3	IPR003644
Domain	Calx-beta	FRAS1 ADGRV1 FREM2	1.46e-05	9	106	3	PF03160
Domain	A2M	CD109 C4A C4B	2.07e-05	10	106	3	PF00207
Domain	A2M_N_2	CD109 C4A C4B	2.07e-05	10	106	3	IPR011625
Domain	A2M_comp	CD109 C4A C4B	2.07e-05	10	106	3	IPR011626
Domain	A2M_recep	CD109 C4A C4B	2.07e-05	10	106	3	PF07677
Domain	A2M_comp	CD109 C4A C4B	2.07e-05	10	106	3	PF07678
Domain	A2M_N	CD109 C4A C4B	2.07e-05	10	106	3	PF01835
Domain	A2M_N	CD109 C4A C4B	2.07e-05	10	106	3	IPR002890
Domain	A-macroglobulin_rcpt-bd	CD109 C4A C4B	2.07e-05	10	106	3	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	CD109 C4A C4B	2.07e-05	10	106	3	PS00477
Domain	A2M_N_2	CD109 C4A C4B	2.07e-05	10	106	3	PF07703
Domain	Macroglobln_a2	CD109 C4A C4B	2.07e-05	10	106	3	IPR001599
Domain	Rav1p_C	DMXL2 DMXL1	3.19e-05	2	106	2	IPR022033
Domain	Rav1p_C	DMXL2 DMXL1	3.19e-05	2	106	2	PF12234
Domain	CADHERIN_1	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2 CLSTN2 CDH24	4.48e-05	113	106	6	PS00232
Domain	Cadherin	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2 CLSTN2 CDH24	4.48e-05	113	106	6	PF00028
Domain	CADHERIN_2	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2 CLSTN2 CDH24	4.71e-05	114	106	6	PS50268
Domain	-	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2 CLSTN2 CDH24	4.71e-05	114	106	6	2.60.40.60
Domain	Cadherin-like	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2 CLSTN2 CDH24	5.19e-05	116	106	6	IPR015919
Domain	Cadherin_tail	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2	5.60e-05	37	106	4	PF15974
Domain	Cadherin_CBD	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2	5.60e-05	37	106	4	IPR031904
Domain	Cadherin_C	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2	9.29e-05	42	106	4	IPR032455
Domain	Cadherin_C_2	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2	9.29e-05	42	106	4	PF16492
Domain	Terpenoid_cyclase/PrenylTrfase	CD109 C4A C4B	1.36e-04	18	106	3	IPR008930
Domain	Anaphylatoxin_comp_syst	C4A C4B	3.16e-04	5	106	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	3.16e-04	5	106	2	IPR001840
Domain	Cadherin_CS	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2 CDH24	3.92e-04	109	106	5	IPR020894
Domain	EPTP	ADGRV1 LGI1	4.72e-04	6	106	2	PF03736
Domain	EPTP	ADGRV1 LGI1	4.72e-04	6	106	2	IPR005492
Domain	PEROXIDASE_1	MPO EPX	4.72e-04	6	106	2	PS00435
Domain	Cadherin_2	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2	5.09e-04	65	106	4	PF08266
Domain	Cadherin_N	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2	5.09e-04	65	106	4	IPR013164
Domain	ANATO	C4A C4B	6.58e-04	7	106	2	SM00104
Domain	ANAPHYLATOXIN_2	C4A C4B	6.58e-04	7	106	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	6.58e-04	7	106	2	PS01177
Domain	EAR	ADGRV1 LGI1	6.58e-04	7	106	2	IPR009039
Domain	ANATO	C4A C4B	6.58e-04	7	106	2	PF01821
Domain	EAR	ADGRV1 LGI1	6.58e-04	7	106	2	PS50912
Domain	Anaphylatoxin/fibulin	C4A C4B	6.58e-04	7	106	2	IPR000020
Domain	ACTINS_1	ACTB ACTG1	8.74e-04	8	106	2	PS00406
Domain	A2M_N_2	CD109 C4A	8.74e-04	8	106	2	SM01359
Domain	-	CD109 C4A	8.74e-04	8	106	2	2.60.40.690
Domain	A2M_recep	CD109 C4A	8.74e-04	8	106	2	SM01361
Domain	A2M	CD109 C4A	8.74e-04	8	106	2	SM01360
Domain	An_peroxidase	MPO EPX	1.39e-03	10	106	2	PF03098
Domain	Haem_peroxidase_animal	MPO EPX	1.39e-03	10	106	2	IPR019791
Domain	Rap_GAP	TSC2 SIPA1	1.39e-03	10	106	2	PF02145
Domain	Haem_peroxidase	MPO EPX	1.39e-03	10	106	2	IPR010255
Domain	PEROXIDASE_3	MPO EPX	1.39e-03	10	106	2	PS50292
Domain	-	MPO EPX	1.39e-03	10	106	2	1.10.640.10
Domain	Rap_GAP_dom	TSC2 SIPA1	1.70e-03	11	106	2	IPR000331
Domain	RAPGAP	TSC2 SIPA1	1.70e-03	11	106	2	PS50085
Domain	-	CD109 C4A	2.03e-03	12	106	2	1.50.10.20
Domain	-	LGALS9C CLSTN2 ADGRV1 LGALS1	2.10e-03	95	106	4	2.60.120.200
Domain	Znf_RING_CS	PHRF1 RNF212 CUL9 TRIM24 SH3RF2	2.38e-03	163	106	5	IPR017907
Domain	Galectin_CRD	LGALS9C LGALS1	3.19e-03	15	106	2	IPR001079
Domain	Gal-bind_lectin	LGALS9C LGALS1	3.19e-03	15	106	2	PF00337
Domain	Gal-bind_lectin	LGALS9C LGALS1	3.19e-03	15	106	2	SM00908
Domain	GALECTIN	LGALS9C LGALS1	3.19e-03	15	106	2	PS51304
Domain	GLECT	LGALS9C LGALS1	3.19e-03	15	106	2	SM00276
Domain	ANK_REPEAT	POTEF BCORL1 MUC16 POTEE ANKRD13C POTEI	3.22e-03	253	106	6	PS50088
Domain	ANK_REP_REGION	POTEF BCORL1 MUC16 POTEE ANKRD13C POTEI	3.28e-03	254	106	6	PS50297
Domain	-	DAB2IP PLXNA3	3.64e-03	16	106	2	1.10.506.10
Domain	Gal_mutarotase_SF_dom	MAN2B1 LGI1	4.10e-03	17	106	2	IPR011013
Domain	C345C	C4A C4B	4.10e-03	17	106	2	SM00643
Domain	RasGAP_dom	DAB2IP PLXNA3	4.60e-03	18	106	2	IPR001936
Domain	NTR	C4A C4B	5.12e-03	19	106	2	PF01759
Domain	Cyclophilin-type_PPIase_CS	PPID PPIH	5.12e-03	19	106	2	IPR020892
Domain	Netrin_module_non-TIMP	C4A C4B	5.12e-03	19	106	2	IPR018933
Pathway	KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAB_C_D_TO_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY	ACTB ACTG1 TLN1	1.29e-05	9	77	3	M47725
Pathway	REACTOME_CELL_CELL_JUNCTION_ORGANIZATION	SDK2 ACTB ACTG1 CDH24	1.33e-04	48	77	4	MM15069
Pathway	REACTOME_IRE1ALPHA_ACTIVATES_CHAPERONES	DCTN1 PLA2G4B TLN1 MYDGF	1.57e-04	50	77	4	M27282
Pubmed	Identification of a novel actin isoform in hepatocellular carcinoma.	POTEF ACTB ACTG1 POTEE POTEI	8.07e-10	15	109	5	16824795
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DAB2IP SEMA6B PLXNA3 FRAS1 MAN2B1 CUL9 TSC2 WRAP53 NUBPL DCTN1 PPP1R26 LIME1 MROH1 MTHFR PLA2G4B TLN1 ABCC10 PICK1	1.04e-08	1105	109	18	35748872
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DCDC1 TPRN PHRF1 CUL9 CLSTN2 POGZ SIPA1 NUBPL TRIM24 TUBGCP5 SIRT5 PRPF3 SV2A MTHFR NFRKB PPIH SPATC1L	7.30e-08	1116	109	17	31753913
Pubmed	Critical role of TPRN rings in the stereocilia for hearing.	TPRN ACTB PTPRQ	1.20e-07	4	109	3	37952086
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	MPO DDAH2 MAN2B1 POTEF ACTB ACTG1 EPX LGALS1 POTEE FREM2 TLN1 NID1 C4A C4B POTEI CTSG	2.36e-07	1070	109	16	23533145
Pubmed	Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies.	MPO C4A C4B	2.98e-07	5	109	3	17200182
Pubmed	Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.	FRAS1 FREM2 NID1	2.98e-07	5	109	3	17596926
Pubmed	Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice.	COL6A2 FRAS1 NID1	1.66e-06	8	109	3	12766770
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PLXNA3 PCDHGB2 PCDHGA9 RBBP8 PCDHGA3 POTEF PCDHGA2 ACO2 ACTB ACTG1 PTPN21 EPX DCTN1 HNRNPU POTEE POTEI PICK1	2.54e-06	1442	109	17	35575683
Pubmed	The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.	COL6A2 FRAS1 FREM2	3.54e-06	10	109	3	15345741
Pubmed	Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.	POTEF ACTB ACTG1 POTEE C4A C4B	6.22e-06	143	109	6	22516433
Pubmed	Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.	DMXL2 POTEF ACTB POTEE LIME1 POTEI	7.87e-06	149	109	6	22664934
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	9.73e-06	2	109	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	9.73e-06	2	109	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	9.73e-06	2	109	2	15998580
Pubmed	Beta- and gamma-cytoplasmic actins are required for meiosis in mouse oocytes.	ACTB ACTG1	9.73e-06	2	109	2	21778137
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	9.73e-06	2	109	2	19062096
Pubmed	Uncovering a new role for peroxidase enzymes as drivers of angiogenesis.	MPO EPX	9.73e-06	2	109	2	26386352
Pubmed	De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome.	ACTB ACTG1	9.73e-06	2	109	2	22366783
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	9.73e-06	2	109	2	19933335
Pubmed	TACC3-TSC2 maintains nuclear envelope structure and controls cell division.	TSC2 TACC3	9.73e-06	2	109	2	20237422
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	9.73e-06	2	109	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	9.73e-06	2	109	2	17645767
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	9.73e-06	2	109	2	12207352
Pubmed	Prenatal presentation and diagnosis of Baraitser-Winter syndrome using exome sequencing.	ACTB ACTG1	9.73e-06	2	109	2	32588558
Pubmed	A C-terminal dimerization motif is required for focal adhesion targeting of Talin1 and the interaction of the Talin1 I/LWEQ module with F-actin.	ACTG1 TLN1	9.73e-06	2	109	2	17722883
Pubmed	Identification of two novel CAKUT-causing genes by massively parallel exon resequencing of candidate genes in patients with unilateral renal agenesis.	FRAS1 FREM2	9.73e-06	2	109	2	21900877
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	9.73e-06	2	109	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	9.73e-06	2	109	2	22387014
Pubmed	Baraitser-Winter cerebrofrontofacial syndrome.	ACTB ACTG1	9.73e-06	2	109	2	27625340
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	9.73e-06	2	109	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	9.73e-06	2	109	2	23918728
Pubmed	Inflammatory peroxidases promote breast cancer progression in mice via regulation of the tumour microenvironment.	MPO EPX	9.73e-06	2	109	2	28260049
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	9.73e-06	2	109	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	9.73e-06	2	109	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	9.73e-06	2	109	2	4216347
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	9.73e-06	2	109	2	6950384
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	9.73e-06	2	109	2	8660986
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	9.73e-06	2	109	2	8428773
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	9.73e-06	2	109	2	24638111
Pubmed	A primate-specific POTE-actin fusion protein plays a role in apoptosis.	POTEF POTEE	9.73e-06	2	109	2	19669888
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	9.73e-06	2	109	2	21345967
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	9.73e-06	2	109	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	9.73e-06	2	109	2	2302180
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	9.73e-06	2	109	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	9.73e-06	2	109	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	9.73e-06	2	109	2	29080553
Pubmed	Isolation of cDNA clones for mouse cytoskeletal gamma-actin and differential expression of cytoskeletal actin mRNAs in mouse cells.	ACTB ACTG1	9.73e-06	2	109	2	3221869
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	9.73e-06	2	109	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	9.73e-06	2	109	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	9.73e-06	2	109	2	17728371
Pubmed	Structure and organization of the C4 genes.	C4A C4B	9.73e-06	2	109	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	9.73e-06	2	109	2	6149581
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	9.73e-06	2	109	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	9.73e-06	2	109	2	3542363
Pubmed	Crystal structure of the human U4/U6 small nuclear ribonucleoprotein particle-specific SnuCyp-20, a nuclear cyclophilin.	PRPF3 PPIH	9.73e-06	2	109	2	10713041
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	9.73e-06	2	109	2	2387317
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	9.73e-06	2	109	2	16908004
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	9.73e-06	2	109	2	7365238
Pubmed	Molecular study of 33 families with Fraser syndrome new data and mutation review.	FRAS1 FREM2	9.73e-06	2	109	2	18671281
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	9.73e-06	2	109	2	7391573
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	9.73e-06	2	109	2	17971360
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	9.73e-06	2	109	2	29928053
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	9.73e-06	2	109	2	17971229
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	9.73e-06	2	109	2	6881182
Pubmed	Novel loss of function variants in FRAS1 AND FREM2 underlie renal agenesis in consanguineous families.	FRAS1 FREM2	9.73e-06	2	109	2	32643034
Pubmed	Partial C4 deficiency in juvenile idiopathic arthritis patients.	C4A C4B	9.73e-06	2	109	2	17921792
Pubmed	Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.	C4A C4B	9.73e-06	2	109	2	21880985
Pubmed	Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.	C4A C4B	9.73e-06	2	109	2	6978711
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	9.73e-06	2	109	2	35898513
Pubmed	Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.	C4A C4B	9.73e-06	2	109	2	28873507
Pubmed	Measurements of spatiotemporal changes in G-actin concentration reveal its effect on stimulus-induced actin assembly and lamellipodium extension.	ACTB ACTG1	9.73e-06	2	109	2	21502360
Pubmed	The evolution and complexity of the genes encoding the cytoskeletal proteins of human epidermal cells.	ACTB ACTG1	9.73e-06	2	109	2	6686106
Pubmed	Actin amino-acid sequences. Comparison of actins from calf thymus, bovine brain, and SV40-transformed mouse 3T3 cells with rabbit skeletal muscle actin.	ACTB ACTG1	9.73e-06	2	109	2	213279
Pubmed	The First Korean Case of Baraitser-Winter Cerebro-Fronto-Facial Syndrome with a Novel Mutation in ACTB Diagnosed Via Targeted Gene Panel Sequencing and Literature Review.	ACTB ACTG1	9.73e-06	2	109	2	33334799
Pubmed	Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.	C4A C4B	9.73e-06	2	109	2	276882
Pubmed	Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.	C4A C4B	9.73e-06	2	109	2	6832377
Pubmed	Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.	C4A C4B	9.73e-06	2	109	2	3794341
Pubmed	β-Actin specifically controls cell growth, migration, and the G-actin pool.	ACTB ACTG1	9.73e-06	2	109	2	21900491
Pubmed	Hereditary eosinophil peroxidase deficiency: immunochemical and spectroscopic studies and evidence for a compound heterozygosity of the defect.	MPO EPX	9.73e-06	2	109	2	7809065
Pubmed	Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.	C4A C4B	9.73e-06	2	109	2	22785613
Pubmed	Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.	C4A C4B	9.73e-06	2	109	2	32691186
Pubmed	The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.	C4A C4B	9.73e-06	2	109	2	8390682
Pubmed	Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).	C4A C4B	9.73e-06	2	109	2	3902619
Pubmed	Beta and gamma-cytoplasmic actins display distinct distribution and functional diversity.	ACTB ACTG1	9.73e-06	2	109	2	19638415
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	9.73e-06	2	109	2	7373044
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	9.73e-06	2	109	2	3696167
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	9.73e-06	2	109	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	9.73e-06	2	109	2	16098595
Pubmed	Botulinum C2 toxin ADP-ribosylates cytoplasmic beta/gamma-actin in arginine 177.	ACTB ACTG1	9.73e-06	2	109	2	3335520
Pubmed	Association of human immunodeficiency virus Nef protein with actin is myristoylation dependent and influences its subcellular localization.	ACTB ACTG1	9.73e-06	2	109	2	9288906
Pubmed	High level expression of transfected beta- and gamma-actin genes differentially impacts on myoblast cytoarchitecture.	ACTB ACTG1	9.73e-06	2	109	2	1577857
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	9.73e-06	2	109	2	15787745
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	9.73e-06	2	109	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	9.73e-06	2	109	2	6559257
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	9.73e-06	2	109	2	34299197
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	9.73e-06	2	109	2	20506482
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	9.73e-06	2	109	2	12480675
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	9.73e-06	2	109	2	26800705
Pubmed	Baraitser-Winter Cerebrofrontofacial Syndrome	ACTB ACTG1	9.73e-06	2	109	2	26583190
Interaction	IL5RA interactions	SEMA6B PLXNA3 COL6A2 FRAS1 MAN2B1 POTEF KREMEN2 C4A	3.21e-07	124	107	8	int:IL5RA
Interaction	LOC254896 interactions	COL6A2 POTEF ADGRV1 NUBPL FREM2	3.15e-06	43	107	5	int:LOC254896
Interaction	ACTG2 interactions	POTEF ACTB ACTG1 POTEE POTEI	6.08e-06	49	107	5	int:ACTG2
Interaction	POTEJ interactions	ACTB ACTG1 CUL9 POTEE POTEI	8.18e-06	52	107	5	int:POTEJ
Interaction	IFNE interactions	FRAS1 CD109 ADGRV1 POTEE	1.20e-05	27	107	4	int:IFNE
Interaction	ALKAL2 interactions	CD109 ADGRV1 POTEE	2.33e-05	11	107	3	int:ALKAL2
Interaction	PCDHGA9 interactions	PDXDC1 PCDHGB2 PCDHGA9 PCDHGA3	2.73e-05	33	107	4	int:PCDHGA9
Interaction	CEACAM8 interactions	PLXNA3 FRAS1 SDK2 MAN2B1 ADGRV1 FREM2	4.15e-05	119	107	6	int:CEACAM8
Interaction	GGH interactions	PDXDC1 PLXNA3 COL6A2 FRAS1 MAN2B1 ACO2 ADGRV1 TRIM24	4.65e-05	243	107	8	int:GGH
Interaction	LYPD4 interactions	SEMA6B PLXNA3 COL6A2 MAN2B1 POTEF WRAP53	5.00e-05	123	107	6	int:LYPD4
Interaction	DEFB135 interactions	PLXNA3 COL6A2 CD109 ADGRV1	7.20e-05	42	107	4	int:DEFB135
Interaction	SCGB1D1 interactions	PLXNA3 FRAS1 CD109 ADGRV1 FREM2 C4A	7.73e-05	133	107	6	int:SCGB1D1
Interaction	TOP3B interactions	DAB2IP SEMA6B PLXNA3 FRAS1 MAN2B1 ACTG1 CUL9 TSC2 WRAP53 NUBPL DCTN1 HNRNPU PPP1R26 LIME1 MROH1 MTHFR PLA2G4B TLN1 ABCC10 PICK1	8.32e-05	1470	107	20	int:TOP3B
Interaction	ST8SIA4 interactions	PLXNA3 FRAS1 CD109 ADGRV1 FREM2	8.50e-05	84	107	5	int:ST8SIA4
Interaction	CMA1 interactions	FRAS1 CD109 ADGRV1 FREM2	1.03e-04	46	107	4	int:CMA1
Interaction	TAFA5 interactions	SDK2 ADGRV1 FREM2	1.12e-04	18	107	3	int:TAFA5
Interaction	TAFAZZIN interactions	PLXNA3 COL6A2 FRAS1 CD109 ADGRV1 FREM2 NID1	1.19e-04	207	107	7	int:TAFAZZIN
Interaction	HOXC5 interactions	PPID SIRT5 TLN1 C4A	1.22e-04	48	107	4	int:HOXC5
Interaction	HS1BP3 interactions	MPO PDXDC1 DMXL2 CTSG	1.32e-04	49	107	4	int:HS1BP3
Interaction	MAGEA10 interactions	POTEF ACTB CUL9 TRIM24	1.43e-04	50	107	4	int:MAGEA10
Interaction	CTSG interactions	COL6A2 FRAS1 FREM2 CTSG PICK1	1.52e-04	95	107	5	int:CTSG
Cytoband	5q31	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2	1.76e-04	115	110	4	5q31
Cytoband	2q21.1	POTEF POTEE POTEI	3.75e-04	58	110	3	2q21.1
Cytoband	17q23.1	MPO EPX	6.68e-04	16	110	2	17q23.1
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	CD109 C4A C4B	6.37e-06	9	78	3	1234
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEF POTEE POTEI	2.14e-05	13	78	3	685
GeneFamily	Clustered protocadherins	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2	1.67e-04	64	78	4	20
GeneFamily	Actins	ACTB ACTG1	2.73e-04	6	78	2	929
GeneFamily	Galectins	LGALS9C LGALS1	1.86e-03	15	78	2	629
GeneFamily	Cathepsins	CTSE CTSG	1.86e-03	15	78	2	470
GeneFamily	Cyclophilin peptidylprolyl isomerases	PPID PPIH	3.00e-03	19	78	2	909
GeneFamily	Ankyrin repeat domain containing	POTEF BCORL1 POTEE ANKRD13C POTEI	3.94e-03	242	78	5	403
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PHRF1 TSC2 PPP1R26 SH3RF2	7.80e-03	181	78	4	694
GeneFamily	CD molecules\|Tetraspanins	UPK1A TSPAN33	8.90e-03	33	78	2	768
ToppCell	10x5'v1-week_12-13\|World / cell types per 3 fetal stages;per 3',per 5'	MPO MAN2B1 ACTB ACTG1 LGALS1 MYDGF CTSG	6.03e-07	197	110	7	4b107359f2d703a1d0348932a6b64eb447d30b3d
ToppCell	Parenchymal-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A2 UPK1A PCDHGA2 CLSTN2 CDH24 NID1 C4B	6.24e-07	198	110	7	0dc5806714fb3d3983e9d19fa7a108e93a8090ed
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A2 GPR162 LGALS1 AGBL3 PLA2G4B C4A	5.20e-06	177	110	6	ac90e4ce5be304a5a7473736397327010f2d1999
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 MUC16 LGALS1 FREM2 SV2A C4B	5.37e-06	178	110	6	bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 MUC16 LGALS1 FREM2 SV2A C4B	5.37e-06	178	110	6	c413861148129be1ee94f2ceb5999840217eebe5
ToppCell	Smart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	POTEF ACTB TSPAN33 POTEE TLN1 POTEI	5.72e-06	180	110	6	fb3d549c2a69b2157a486786ddd775ca16699ed0
ToppCell	Smart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic-platelet\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	POTEF ACTB TSPAN33 POTEE TLN1 POTEI	5.72e-06	180	110	6	beb4d777e0c5fa0a59672dbc3dbb7732498605ff
ToppCell	facs-Skin-Anagen-24m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A2 SIPA1 LGALS1 NALCN DIO2 C4B	7.12e-06	187	110	6	908df5520142d65fe32a003d26be14965082a1ea
ToppCell	facs-Skin-Anagen-24m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A2 SIPA1 LGALS1 NALCN DIO2 C4B	7.12e-06	187	110	6	c1dfab0b0d7f519b9f13f4e0365ab41c4b2ae1ec
ToppCell	facs-Skin-Anagen-24m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A2 SIPA1 LGALS1 NALCN DIO2 C4B	7.12e-06	187	110	6	b486cc5ac678051fea9d4c7db53b26a5a8427e60
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN2B1 ACTB ACTG1 NXNL2 HNRNPU LIME1	7.80e-06	190	110	6	d85b34d19af43d83ebe728f3c7bbefd3792df4a6
ToppCell	Parenchymal-10x5prime-Stromal-Mesofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 DAB1 MUC16 PTPRQ C4A C4B	9.58e-06	197	110	6	88a86286b9c3ea3b076d7464faec42d0392ee7f8
ToppCell	Parenchymal-10x5prime-Stromal-Mesofibroblastic-Mesothelia\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 DAB1 MUC16 PTPRQ C4A C4B	9.58e-06	197	110	6	2773d2eb5f232a7e49da116efffcb6bf5eb90810
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A2 NALCN DIO2 NID1 C4A C4B	9.86e-06	198	110	6	7a0c4dbc8c99968d42af00a718f4fedc544599ec
ToppCell	10x5'v1-week_14-16-Myeloid_monocytic\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MPO DMXL2 ICAM3 ACTB ACTG1 LGALS1	1.01e-05	199	110	6	5caaf66b6cddcc8f0d0aee3c9ba80d02075e87e5
ToppCell	10x5'v1-week_14-16-Myeloid_monocytic-monocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MPO DMXL2 ICAM3 ACTB ACTG1 LGALS1	1.01e-05	199	110	6	7f5d47e49776114d9f4a42017fead9eeb415a94c
ToppCell	COVID-19-Fibroblasts-Vascular_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	COL6A2 ACTB ACTG1 LGALS1 NID1 CX3CL1	1.04e-05	200	110	6	c7f82196a0768ad96b1df8b8915bc541fb118a76
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MPO ADGRV1 RHO RECQL4 CTSG	1.54e-05	126	110	5	69b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MPO ADGRV1 RHO RECQL4 CTSG	1.54e-05	126	110	5	6cb89754010d64875e115da6c5805efac7a4a82d
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SDK2 ICAM3 NXNL2 SIPA1 TACC3	4.29e-05	156	110	5	f5889a6899904dfb7f596600b3a76857cf9d5378
ToppCell	facs-Brain_Myeloid-Cerebellum\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO UPK1A LGALS1 CTSE CTSG	4.29e-05	156	110	5	28c4fb4d2c6c47696c3a6722998f9da5a8923323
ToppCell	Severe-Lymphoid-NK-Proliferating_T\|Severe / Condition, Lineage, Cell class and cell subclass	DCDC1 AGBL3 KIR3DX1 PVRIG NID1	4.84e-05	160	110	5	cb2276d9bd78508644420e9580d3c17b914224cb
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Tem/emra_CD8\|GI_small-bowel / Manually curated celltypes from each tissue	MPO ACTB ACTG1 NPC1L1 CTSG	5.29e-05	163	110	5	1a8c79903ed416f286ebe8a9922233affbc55d82
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DAB2IP CLSTN2 TSPAN33 CDH24 RECQL4	5.44e-05	164	110	5	cdb8cd2d6b369189ea77e4946738e2816d502e03
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAN2B1 KREMEN2 ACTB TSPAN33 CLCA2	5.44e-05	164	110	5	5638d95c7cc5e59c4a7bda30268a904a01861a5f
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DAB2IP CLSTN2 TSPAN33 CDH24 RECQL4	5.44e-05	164	110	5	5dbfcdd450f652b16d97da53b528d4584b0eabcf
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DAB2IP CLSTN2 TSPAN33 CDH24 RECQL4	5.44e-05	164	110	5	f1423f4434af4af9c60c8a5b0b0abec4a7df9401
ToppCell	facs-Trachea-nan-18m-Epithelial-mucus_secreting_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPRN CLSTN2 TSPAN33 CDH24 RECQL4	5.60e-05	165	110	5	7e7643834ed483aec04f513cca38d6367fda9ff8
ToppCell	Monocytes-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	KREMEN2 ACTB LGALS1 TLN1 TACC3	5.60e-05	165	110	5	83d06210a50073fbb7082eabd8298dd355c40416
ToppCell	facs-Spleen-nan-24m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO FRAS1 UPK1A LGALS1 CTSG	5.60e-05	165	110	5	966ed14d479e0f1a507f46d08408aa99bd7682ae
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	FRAS1 MUC16 NXNL2 POTEE PTPRQ	5.76e-05	166	110	5	4d63c758d46e73311b864148c646bf081498dee7
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|368C / Donor, Lineage, Cell class and subclass (all cells)	FRAS1 MUC16 NXNL2 POTEE PTPRQ	5.76e-05	166	110	5	4160ccf9291072a6e2782f9ad141bc9a9747f3ad
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A2 FRAS1 MUC16 SH3RF2 C4B	5.93e-05	167	110	5	c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 MUC16 FREM2 SH3RF2 C4B	5.93e-05	167	110	5	7abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCell	facs-Spleen-nan-24m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO FRAS1 UPK1A LGALS1 CTSG	5.93e-05	167	110	5	9a8e291c082d7c26bab21df77bd36ce927032a70
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 MUC16 FREM2 SH3RF2 C4B	5.93e-05	167	110	5	d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A2 FRAS1 MUC16 SH3RF2 C4B	5.93e-05	167	110	5	351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCell	10x5'v1-week_17-19-Myeloid_DC-DC-DC1\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ACTB CLSTN2 ADGRV1 TSPAN33 SH3RF2	6.27e-05	169	110	5	488ba50631a64cb9e0d69219491c66ac824c9e7d
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 UPK1A ADGRV1 NALCN C4B	6.27e-05	169	110	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_2\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	ACTB ACTG1 GPR162 TBR1	6.73e-05	88	110	4	3a92f76e4db86486cb265301e6056af791a11a63
ToppCell	PND03-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MPO MAN2B1 ACTB LGALS1 CTSG	7.01e-05	173	110	5	8ca650542655c27516029e5bace97ff1b9dcc256
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Lymphocytic-B_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO KREMEN2 VWA7 CDH24 CTSG	7.01e-05	173	110	5	a693772987f1baee533dd0bd285a3c7b5619a73b
ToppCell	10x3'2.3-week_14-16-Myeloid_DC-DC-DC_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ACTB ACTG1 KHDC1L PLA2G4B POTEI	7.01e-05	173	110	5	a361474ad6f058bb3d3f9671bae697205535090b
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DDAH2 COL6A2 ACTB ACTG1 LGALS1	7.20e-05	174	110	5	9d22a554617a93701d0945de63cc3e7b24322c40
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A2 ACTB ACTG1 LGALS1 SV2A	7.60e-05	176	110	5	fcf324e6402819683f95e0dd94bf1f777c7f4c76
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DMXL2 TSC2 NUBPL MROH1 SH3RF2	7.81e-05	177	110	5	e1e45956887371b1c18f1eb479dd930031497520
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A2 ACTB ACTG1 LGALS1 SV2A	8.23e-05	179	110	5	68ccfe66474d049a926afc21bffa231446becc69
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NXNL2 VWA7 LIME1 GABBR1 SPATC1L	8.45e-05	180	110	5	81c7086399256260e59424b7410feec514ce8027
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF20B PACRGL TACC3 PPIH CTSE	8.45e-05	180	110	5	87347af8f28cf7c486c19f3f98c0afb022c323b5
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-FCRL4+_Memory_B\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KREMEN2 ACTB ACTG1 MUC16 TSPAN33	8.45e-05	180	110	5	eedb6d89680f968167afb1dcd132c9de9096b50f
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO TSPAN33 DIO2 C4B CTSG	8.45e-05	180	110	5	54e3f289a37d4cfbfca4fb284c3b52e9c7d9da97
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO TSPAN33 DIO2 C4B CTSG	8.45e-05	180	110	5	bfc8568d57034dd9c9e07edae94479a48ca0706d
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NXNL2 VWA7 LGALS1 LIME1 SPATC1L	8.67e-05	181	110	5	c7ad10a696d94b9ee91cd7e62761d356d5106eda
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NXNL2 VWA7 LGALS1 LIME1 SPATC1L	8.67e-05	181	110	5	eaa3a2c268cce527004ae656d35e037b984fb4c7
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A2 CLSTN2 NALCN MICAL2 NID1	8.90e-05	182	110	5	44764676ed3f51ba171ce63f669390392fa50a43
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A2 CLSTN2 NALCN MICAL2 NID1	8.90e-05	182	110	5	d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell	IPF-Epithelial-Mesothelial\|World / Disease state, Lineage and Cell class	COL6A2 MUC16 PTPRQ C4A C4B	9.13e-05	183	110	5	7df20e3172a1220ff427f30181f4f0c3b7fe2d42
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|lymph-node_spleen / Manually curated celltypes from each tissue	MPO CD109 LGALS1 NID1 CTSG	9.37e-05	184	110	5	f93373fcde5c31f4ffe67ca0f3ea7f4e906dc88b
ToppCell	COPD-Epithelial-Mesothelial\|World / Disease state, Lineage and Cell class	COL6A2 MUC16 PTPRQ C4A C4B	9.61e-05	185	110	5	23579988036fc1925992c31919750f9b3fe9f790
ToppCell	10x5'v1-week_17-19-Myeloid_monocytic-monocyte-MOP\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MPO PCDHGB2 LGALS1 RECQL4 CTSG	9.61e-05	185	110	5	d1c4fc794c2bd8187abf8f45dc76ba474c40daae
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ACTB ACTG1 KIF20B LGALS1 TACC3	9.61e-05	185	110	5	6aeae77a087d695b1e58c5f63265e7113aa2e343
ToppCell	HSPCs-Eo/Baso_prog.\|World / Lineage and Cell class	MPO MAN2B1 EPX LGALS1 CTSG	9.61e-05	185	110	5	b40ea11f5e536438b400ca5fddfd4559789036bd
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDAH2 COL6A2 LGALS1 NID1 C4B	9.86e-05	186	110	5	ff6ccfdf2509f96caa10281c29a95b432f6c6dcc
ToppCell	facs-Lung-24m-Hematologic-myeloid-leukocyte\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MPO UPK1A CTSG ABCC10 PICK1	1.04e-04	188	110	5	61b6047affa18c5e71210fcce449e2bbe7cf141b
ToppCell	facs-Lung-24m-Hematologic-myeloid-leukocyte-proliferating_myeloid_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MPO UPK1A CTSG ABCC10 PICK1	1.04e-04	188	110	5	797ce39602f0f78081eb44a21da0d9443f7fd9cf
ToppCell	COPD-Epithelial-Mesothelial\|COPD / Disease state, Lineage and Cell class	COL6A2 MUC16 PTPRQ C4A C4B	1.06e-04	189	110	5	79bb2593ad5d17f94b17972884241f03a0f43770
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A2 ACTB ACTG1 LGALS1 NID1	1.06e-04	189	110	5	9e1a51997ef9b6999d9b40cf0a55e561e3b4a84c
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD109 LGALS1 MICAL2 DIO2 C4B	1.06e-04	189	110	5	562f8bf5a7d38afb4a8f2415d617d5f79cfb7e3f
ToppCell	facs-Marrow-KLS-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO MAN2B1 LGALS1 TSPAN33 CTSG	1.06e-04	189	110	5	b28a0e2d5a5f512f9b137b162b195bdc3d5ee9ba
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD109 LGALS1 MICAL2 DIO2 C4B	1.06e-04	189	110	5	270dd4a0fc5260288fe6829837942c78b40ecec4
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDAH2 COL6A2 LGALS1 NID1 C4B	1.09e-04	190	110	5	d13fd234caa3fc69d8a59bc0060cdacdf716ee55
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A2 ACTB ACTG1 LGALS1 NID1	1.09e-04	190	110	5	7f6dafd5418764d67f6d5ec2153233b791910e81
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A2 FRAS1 NXNL2 LGALS1 C4B	1.12e-04	191	110	5	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDAH2 COL6A2 LGALS1 NID1 C4B	1.14e-04	192	110	5	fc940f91ff8e051631dbf25e6e8d73cf8337eccb
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDAH2 COL6A2 LGALS1 NID1 C4B	1.14e-04	192	110	5	7a2e79490e4f7058bb76b46c45b5df9f729e3146
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDAH2 COL6A2 LGALS1 NID1 C4B	1.17e-04	193	110	5	25248b8e65d558b1a96a87c93e3e5b4c0ba168fe
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDAH2 COL6A2 LGALS1 NID1 C4B	1.17e-04	193	110	5	f1f1097204e07a7bed416425b8256942038a734f
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTB CLSTN2 LGALS1 CLCA2 NID1	1.17e-04	193	110	5	7386fadc13a437f3b0c99b5d116cd3c5f893529c
ToppCell	normal_Lung-Myeloid_cells-CD141+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	ICAM3 CLSTN2 NUBPL TSPAN33 SH3RF2	1.20e-04	194	110	5	d21461682fa755f588afe073abb6a777f339c4cc
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDAH2 COL6A2 LGALS1 NID1 C4B	1.20e-04	194	110	5	889c6e231bdd5b59902c7d2afdc077360b1d3256
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDAH2 COL6A2 LGALS1 NID1 C4B	1.23e-04	195	110	5	773728703bc8969bff0e1de58fe3e1631add0a0a
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	RNF212 ACTG1 TSPAN33 MICAL2 MYDGF	1.23e-04	195	110	5	a04ddf1f191fd814e67fb28503096e1a07ccb79a
ToppCell	facs-Trachea-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDAH2 COL6A2 LGALS1 NID1 C4B	1.23e-04	195	110	5	0d1876f6fdc1eafeb60d6fd7da5bce737d2b4a5a
ToppCell	distal-Hematologic-Natural_Killer_T-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ICAM3 LGALS1 LIME1 KIR3DX1 PVRIG	1.26e-04	196	110	5	05d2a15ba702b07ef59c55891a06da02cdd15f7f
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDAH2 COL6A2 LGALS1 NID1 C4B	1.26e-04	196	110	5	d4676a6b0d9e417795fc9a6bcb1762d3dd656ca9
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	COL6A2 CD109 MICAL2 DIO2 LGI1	1.26e-04	196	110	5	24d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCell	Basal_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	FRAS1 SDK2 CD109 CLCA2 CX3CL1	1.26e-04	196	110	5	3b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCell	Macrophages-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	DDAH2 DMXL2 ACTB CD109 LGALS1	1.26e-04	196	110	5	861c402ed8b8fde3582cc777c1357b45f5a2489b
ToppCell	10x5'v1-week_14-16-Myeloid_DC-DC-DC3\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MAN2B1 ACTB ACTG1 LGALS1 MYDGF	1.26e-04	196	110	5	d4e5b55a32d9c04c6b2ca7806a0d96231918761f
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	FRAS1 CLCA2 NPC1L1 CTSE CX3CL1	1.29e-04	197	110	5	751f19b00f92e1334f653b870d3f7c0c149ff41a
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A2 LGALS1 NALCN NID1 C4B	1.29e-04	197	110	5	2cb1f557ce1400398975de94638126b4522567f3
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)-DC2_L.1.2.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA6B MAN2B1 ACTB TSPAN33 TLN1	1.29e-04	197	110	5	515a2d0ee2bd3fc0a5a0c315e2b0c752e6af7406
ToppCell	Caecum-B_cell-B_cell_IgG_Plasma\|B_cell / Region, Cell class and subclass	DAB2IP LGALS9C KHDC1L SV2A MYDGF	1.29e-04	197	110	5	40c8ff067e8242e2ca083ea04cd6026168191a97
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA6B MAN2B1 ACTB TSPAN33 TLN1	1.29e-04	197	110	5	bfa04e5f4156a01df4217b1f59676edb0a7563e1
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Basal_1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	FRAS1 CLCA2 NPC1L1 CTSE CX3CL1	1.29e-04	197	110	5	2701864e49878c5f323f5133e2c4b0a5a7fff7f5
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A2 KIF20B LGALS1 NID1 TACC3	1.29e-04	197	110	5	29b0a5927f80455eef7b793feabef69fba1a3df1
ToppCell	3'-Broncho-tracheal-Immune_Myeloid\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA6B DMXL2 ACTB LGALS1 TLN1	1.29e-04	197	110	5	d568354aff89ac84dd06360f19100ef578a041ed
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTB CLSTN2 NXNL2 LGALS1 NID1	1.29e-04	197	110	5	e132f4b9deef6a565262c0aa0863cafe28f248e6
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA6B MAN2B1 ACTB TSPAN33 TLN1	1.29e-04	197	110	5	4fccdc69ab4b966de6465f06677435e6f6e6abcd
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FRAS1 CLCA2 NPC1L1 CTSE CX3CL1	1.29e-04	197	110	5	58d809ccb8cc4b1e76acf0b8f996cd0e2637290c
Disease	mental development measurement	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2	1.81e-06	25	105	4	EFO_0008230
Disease	Baraitser-Winter syndrome	ACTB ACTG1	1.25e-05	2	105	2	cv:C1853623
Disease	Iris Coloboma with Ptosis, Hypertelorism, and Mental Retardation	ACTB ACTG1	1.25e-05	2	105	2	C1855722
Disease	Fryns-Aftimos Syndrome	ACTB ACTG1	1.25e-05	2	105	2	C1853623
Disease	Cryptophthalmos syndrome	FRAS1 FREM2	3.75e-05	3	105	2	C0265233
Disease	FRASER SYNDROME 1	FRAS1 FREM2	3.75e-05	3	105	2	C4551480
Disease	Morbilliform Drug Reaction	MPO MTHFR C4B	7.36e-05	23	105	3	C0406537
Disease	Sarcosine measurement	PCDHGB2 PCDHGA3 PCDHGA2	7.36e-05	23	105	3	EFO_0021668
Disease	Drug Eruptions	MPO MTHFR C4B	7.36e-05	23	105	3	C0011609
Disease	Fraser syndrome (implicated_via_orthology)	FRAS1 FREM2	7.49e-05	4	105	2	DOID:0090001 (implicated_via_orthology)
Disease	Macrostomia	FRAS1 ACTG1	7.49e-05	4	105	2	C0024433
Disease	childhood trauma measurement, alcohol consumption measurement	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2	1.22e-04	71	105	4	EFO_0007878, EFO_0007979
Disease	Uveoretinal Coloboma	ACTB ACTG1	2.60e-04	7	105	2	C4554007
Disease	Moyamoya disease (implicated_via_orthology)	ACTB ACTG1	3.46e-04	8	105	2	DOID:13099 (implicated_via_orthology)
Disease	Unilateral agenesis of kidney	FRAS1 FREM2	3.46e-04	8	105	2	C0266294
Disease	autosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)	ACTB ACTG1	3.46e-04	8	105	2	DOID:0110550 (implicated_via_orthology)
Disease	Baraitser-Winter syndrome 1 (implicated_via_orthology)	ACTB ACTG1	3.46e-04	8	105	2	DOID:0081112 (implicated_via_orthology)
Disease	thoracic aortic aneurysm (implicated_via_orthology)	ACTB ACTG1	3.46e-04	8	105	2	DOID:14004 (implicated_via_orthology)
Disease	Autistic Disorder	DAB1 TSC2 MTHFR C4B TBR1 GABBR1	3.50e-04	261	105	6	C0004352
Disease	Graves' disease (is_implicated_in)	MTHFR C4A C4B	3.65e-04	39	105	3	DOID:12361 (is_implicated_in)
Disease	Congenital ocular coloboma (disorder)	ACTB ACTG1	4.44e-04	9	105	2	C0009363
Disease	intestinal atresia (implicated_via_orthology)	ACTB ACTG1	5.54e-04	10	105	2	DOID:10486 (implicated_via_orthology)
Disease	Congenital neurologic anomalies	ACTB ACTG1	5.54e-04	10	105	2	C0497552
Disease	Cranioschisis	ACTB ACTG1	5.54e-04	10	105	2	C0265541
Disease	patent ductus arteriosus (implicated_via_orthology)	ACTB ACTG1	5.54e-04	10	105	2	DOID:13832 (implicated_via_orthology)
Disease	Pulmonary Thromboembolisms	DAB2IP MTHFR	8.09e-04	12	105	2	C0524702
Disease	Pulmonary Embolism	DAB2IP MTHFR	8.09e-04	12	105	2	C0034065
Disease	motor neuron disease (implicated_via_orthology)	WRAP53 DCTN1	8.09e-04	12	105	2	DOID:231 (implicated_via_orthology)
Disease	DEAFNESS, AUTOSOMAL RECESSIVE (disorder)	DMXL2 PTPRQ	9.54e-04	13	105	2	C1846647
Disease	Disorder of eye	FRAS1 ADGRV1 RHO FREM2 PRPF3	9.85e-04	212	105	5	C0015397
Disease	mean platelet volume	PCDHGB2 PCDHGA9 PCDHGA3 PCDHGA2 BCORL1 EPX VWA7 TMEM174 MTHFR NID1 PICK1	1.03e-03	1020	105	11	EFO_0004584
Disease	cystitis (biomarker_via_orthology)	MPO CX3CL1	1.85e-03	18	105	2	DOID:1679 (biomarker_via_orthology)
Disease	response to ketamine	DAB1 PACRGL DIO2	1.93e-03	69	105	3	EFO_0009748
Disease	renal cell carcinoma (is_implicated_in)	MTHFR C4A C4B	1.93e-03	69	105	3	DOID:4450 (is_implicated_in)
Disease	cortical thickness	DCDC1 DAB1 CUL9 ADGRV1 PPID KIF20B MTHFR FBXO42 TACC3 ABCC10 PICK1	2.05e-03	1113	105	11	EFO_0004840
Disease	lymphocyte count	FRAS1 PCDHGB2 PCDHGA9 RBBP8 PCDHGA3 POTEF PCDHGA2 ICAM3 ACTB EPX NUBPL PPID TLN1	2.09e-03	1464	105	13	EFO_0004587
Disease	metabolite measurement, diet measurement	PDXDC1 PDXDC2P GABBR1	2.10e-03	71	105	3	EFO_0004725, EFO_0008111
Disease	Lupus Erythematosus, Systemic	PHRF1 C4A C4B	2.10e-03	71	105	3	C0024141
Disease	autism spectrum disorder (implicated_via_orthology)	TSC2 POGZ SH3RF2 TBR1	2.16e-03	152	105	4	DOID:0060041 (implicated_via_orthology)
Disease	cardiovascular system disease (is_implicated_in)	MPO MTHFR	2.52e-03	21	105	2	DOID:1287 (is_implicated_in)
Disease	Nonsyndromic genetic hearing loss	TPRN ACTG1 PTPRQ	2.55e-03	76	105	3	cv:C5680182
Disease	Lung Neoplasms	DAB2IP MPO ACTB CLCA2 MTHFR	2.62e-03	265	105	5	C0024121
Disease	Malignant neoplasm of lung	DAB2IP MPO ACTB CLCA2 MTHFR	2.66e-03	266	105	5	C0242379
Disease	renal system measurement, blood urea nitrogen measurement	DCDC1 TMEM174	2.77e-03	22	105	2	EFO_0004741, EFO_0004742
Disease	myeloperoxidase (MPO)-DNA complex measurement	MPO EPX	2.77e-03	22	105	2	EFO_0011039
Disease	Sensorineural Hearing Loss (disorder)	DMXL2 ACTB	3.02e-03	23	105	2	C0018784
Disease	Nonsyndromic Deafness	TPRN ACTG1 ADGRV1	3.05e-03	81	105	3	C3711374

Protein segments in the cluster

Peptide	Gene	Start	Entry
SVRNAVTQEFGPVPD	ACO2	631	Q99798
VTPAVLGFRSQAPSE	BHLHB9	226	Q6PI77
TRFVVDPSIFTAQPN	BTBD10	176	Q9BSF8
TADSFGDPFFPRTTQ	AGBL3	41	Q8NEM8
GELPNTFFTTPSAVR	CDX4	256	O14627
TFFTTPSAVRGFQPI	CDX4	261	O14627
PDSPITAFSFSGVNR	RBBP8	161	Q99708
VSQRPGATVPTDFAT	DCTN1	1211	Q14203
AGSARPVAFSVVPTA	C4B	891	P0C0L5
FAGDDAPRAVFPSIV	ACTB	21	P60709
FAGDDAPRAVFPSIV	ACTG1	21	P63261
GSTSSPFVIFPEIVR	BCORL1	681	Q5H9F3
QGAPIRPTSVVSEFS	BCORL1	856	Q5H9F3
VVSPDFTQDVFPVQG	ADGRV1	931	Q8WXG9
PVFPTITATVTFQEF	ANKRD13C	501	Q8N6S4
SFSSRIPVAFPSGDA	DMXL2	541	Q8TDJ6
GTAVPPDVQTLRAFT	CCDC22	16	O60826
PAAQFESARGVTLFP	CLSTN2	646	Q9H4D0
FVSRIPVAFPTGDAN	DMXL1	526	Q9Y485
SSPVNPVVFFDVSIG	PPIH	6	O43447
IPENNPRGASVFSVT	PCDHGA2	461	Q9Y5H1
VPFSNATGVVRSPFE	RHO	11	P08100
EPSAATPFRVTGFLS	DAB2IP	66	Q5VWQ8
VVVFSQAPSGRAPLS	FBXO42	351	Q6P3S6
STPGFFETSRIQTEP	MUC16	8101	Q8WXI7
APVTFFNATPTGRIL	ABCC10	1011	Q5T3U5
FAGDDAPRAVFPSIV	POTEF	721	A5A3E0
PVSAPVGQLRVAEFS	DCDC1	136	M0R2J8
SLEFFPPRTAEGAVN	MTHFR	61	P42898
DFASPERPLVVNFGS	DIO2	116	Q92813
GARSPFETITDNTPF	FRAS1	3236	Q86XX4
TEQREAVFPFQPGSV	LGALS1	71	P09382
GESRAVPSSFSPFVE	NFRKB	436	Q6P4R8
ETNIFSTPREPGSFL	GPR162	416	Q16538
EITFRQSFFSDPAVP	GABBR1	336	Q9UBS5
RAVPVQPAFSTVPFS	LGALS9C	151	Q6DKI2
LFSGSQTPRVEVAAP	ATXN1L	311	P0C7T5
AASPGPRVTFNIQDT	KIAA1109	3651	Q2LD37
HSPGPVTDQFTFRVQ	FREM2	661	Q5SZK8
TISIGSPPQNFTVIF	CTSE	81	P14091
LPFFSVDPQTGVVRT	CDH24	196	Q86UP0
SFVTPTFDQVSPSRG	PLXNA3	931	P51805
SLFSPVREDAPQGTV	PCDHGA9	351	Q9Y5G4
PPGFFVLQVTATDRD	PCDHGB2	256	Q9Y5G2
DFSPESPARVAFTAG	EPX	236	P11678
TPEPAARASFVTGVN	MPO	266	P05164
SSPVVVFRFFQELPG	PDXDC1	386	Q6P996
SPVVVFRFFQELPGS	PDXDC2P	386	Q6P474
GFPEISFQPSSAVVV	NID1	141	P14543
TSLFAVTVAPPGARQ	HNRNPU	191	Q00839
VFSADPIARPSEINF	KIF20B	16	Q96Q89
APGRFESPFSVEAIL	NOTO	41	A8MTQ0
VAPTGVRQVFSELPF	PHRF1	1441	Q9P1Y6
PPAAIGARVFSTVTA	KREMEN2	361	Q8NCW0
FSTGVAEVPPDTRNV	TUBGCP5	416	Q96RT8
PPSTAGRIAEFFTDL	PLA2G4B	546	P0C869
SVANAFGVVPFLPSV	MROH1	151	Q8NDA8
FQANFSVGRATPVPG	KIR3DX1	276	Q9H7L2
SREVPVGIPFFVNVT	ICAM3	441	P32942
TRSNIISFQTPEGAP	PTPRQ	976	Q9UMZ3
PRAVSVGSQPSVFTE	PTPN21	666	Q16825
IPENNPRGASIFSVT	PCDHGA3	461	Q9Y5H0
FGPFFRTNQVILTAP	NPC1L1	401	Q9UHC9
FAGDDAPRAVFPSIV	POTEE	721	Q6S8J3
PGFNVTPSDVRTLVN	PFN4	36	Q8NHR9
SFSFPPNTVTGSERV	CD109	881	Q6YHK3
ADVFSSVPFGTAAVP	DAB1	316	O75553
FSDQVEVFSPPGSDR	COL6A2	101	P12110
NGRTVPSDVVIFPSS	MAN2B1	541	O00754
FTATGQTRVTVVGPP	KHDC1L	61	Q5JSQ8
PAQPTGAFIRAIVSS	CUL9	2121	Q8IWT3
SGVPPEVFTRVSSFL	CTSG	221	P08311
FRDFAVSTVPVSGPS	DDAH2	156	O95865
VFVGEAVPTAAPRNV	SDK2	1616	Q58EX2
AGSARPVAFSVVPTA	C4A	891	P0C0L4
ESNTFFDPRVSIAPS	PRPF3	306	O43395
REASDTGQPIVFSQP	NUBPL	281	Q8TB37
FDVAEREFGIPPVTT	MICAL2	581	O94851
TINPFGEQSRVPSAF	PACRGL	66	Q8N7B6
DFLFSPPEVTGRSSV	TACC3	21	Q9Y6A5
LATASGQRVFPEPTE	WRAP53	476	Q9BUR4
SQPGRVQTFTFPETQ	TBR1	351	Q16650
AFQEVSIRVGSPQPS	RECQL4	241	O94761
SPVASQPIFITTQGF	POGZ	141	Q7Z3K3
SNPSNPRVFFDVDIG	PPID	11	Q08752
AVSRTQDTPAFGPAL	SIPA1	476	Q96FS4
FSAFREAQAGPSPVF	PPP1R26	1116	Q5T8A7
FAGDDAPRAVFPSIV	POTEI	721	P0CG38
PDFGRFTSVADTPSQ	SPATC1L	66	Q9H0A9
FAIGALTTQPESPRF	SV2A	346	Q7L0J3
RASNSAVPPATVEAF	CLCA2	596	Q9UQC9
PFQQAEGTLDTFRTP	RNF212	266	Q495C1
RAPAASGEEFSFVSP	TSPAN33	6	Q86UF1
GRPVVLAVFSTPSNS	SEMA6B	316	Q9H3T3
TRPESIFVPTAQDGA	nan	96	Q9BRP9
EAVGVTSQRPVFCPF	TRIM24	211	O15164
RPAPFEVVFVSADGS	NXNL2	61	Q5VZ03
FSSIPAQISPEGRAA	TLN1	1581	Q9Y490
FTSAFRAATPEVVFP	UPK1A	171	O00322
TIQSVPIPGFSEFRE	TAS1R2	326	Q8TE23
IGIPFNVDVSSFPSR	ZNF33A	121	Q06730
GRLEDFPVNVFSVTP	TMEM174	6	Q8WUU8
AELQPRGSNTFTVVP	TPRN	491	Q4KMQ1
FVPTAIVNPVRSTAG	SH3RF2	486	Q8TEC5
ARGVPVAEFNTETTP	SIRT5	266	Q9NXA8
FSVIGVREPQPAASE	PICK1	191	Q9NRD5
STPIPARGSFVSVEN	PVRIG	276	Q6DKI7
TPAFSPFTLVTQGRA	VWA7	851	Q9Y334
SNFTAVPKRSPVGEF	TSC2	1036	P49815
VGTELFRVPPVSTAA	CX3CL1	181	P78423
VTGTPPAEFVQRLQS	MAPK12	241	P53778
AVSEPTTVAFDVRPG	MYDGF	31	Q969H8
PPDVISLSFVRSGFT	LGI1	66	O95970
VSRDITGPQAAPSAF	LIME1	106	Q9H400
QSSRVEAQPVTDFGP	NALCN	6	Q8IZF0