Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

MYH9 ATP8A1 CENPE SMCHD1 SMARCAL1 PSMC1 ABCC2 MORC2 SMC2 DNAH5 ABCB4

4.11e-056148211GO:0140657
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ATP8A1 GBP7 EIF2S3 SMCHD1 PSMC1 EIF2S3B ABCC2 MORC2 SMC2 DNAH5 ABCB4

3.18e-047758211GO:0017111
GeneOntologyMolecularFunctionATP hydrolysis activity

ATP8A1 SMCHD1 PSMC1 ABCC2 MORC2 SMC2 DNAH5 ABCB4

4.54e-04441828GO:0016887
GeneOntologyMolecularFunctionpyrophosphatase activity

ATP8A1 GBP7 EIF2S3 SMCHD1 PSMC1 EIF2S3B ABCC2 MORC2 SMC2 DNAH5 ABCB4

6.20e-048398211GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ATP8A1 GBP7 EIF2S3 SMCHD1 PSMC1 EIF2S3B ABCC2 MORC2 SMC2 DNAH5 ABCB4

6.26e-048408211GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ATP8A1 GBP7 EIF2S3 SMCHD1 PSMC1 EIF2S3B ABCC2 MORC2 SMC2 DNAH5 ABCB4

6.26e-048408211GO:0016818
GeneOntologyMolecularFunctionprotein-membrane adaptor activity

MYH9 SYNE1 ATG14

8.36e-0445823GO:0043495
GeneOntologyCellularComponenteukaryotic translation initiation factor 2 complex

EIF2S3 EIF2S3B

2.31e-046832GO:0005850
GeneOntologyCellularComponent9+0 motile cilium

ENKUR DNAH5

2.31e-046832GO:0097728
DomainSMC_hinge

SMCHD1 SMC2

2.76e-046812PF06470
DomainSMC_hinge

SMCHD1 SMC2

2.76e-046812SM00968
DomainSMC_hinge

SMCHD1 SMC2

2.76e-046812IPR010935
DomainP-loop_NTPase

MYH9 GBP7 CENPE EIF2S3 SMARCAL1 APAF1 PSMC1 ABCC2 SMC2 DNAH5 ABCB4

1.05e-038488111IPR027417
DomainZnf_C2H2_matrin

ZNF385D ZNF638

1.19e-0312812IPR000690
DomainZF_MATRIN

ZNF385D ZNF638

2.72e-0318812PS50171
Domain-

SMCHD1 MORC2

3.36e-03208123.30.565.10
DomainAAA+_ATPase

PSMC1 ABCC2 DNAH5 ABCB4

3.56e-03144814IPR003593
DomainAAA

PSMC1 ABCC2 DNAH5 ABCB4

3.56e-03144814SM00382
DomainHATPase_C

SMCHD1 MORC2

3.70e-0321812IPR003594
DomainZnf_C2H2_jaz

ZNF385D ZNF638

4.06e-0322812IPR022755
Domainzf-C2H2_jaz

ZNF385D ZNF638

4.06e-0322812PF12171
DomainPWWP

PWWP3B HDGFL2

4.82e-0324812PS50812
DomainABC_membrane

ABCC2 ABCB4

4.82e-0324812PF00664
Domain-

GBP7 EIF2S3 SMARCAL1 APAF1 PSMC1 ABCC2 SMC2 DNAH5 ABCB4

4.94e-037468193.40.50.300
DomainTransl_B-barrel

AARS1 EIF2S3

6.08e-0327812IPR009000
DomainABC_TM1F

ABCC2 ABCB4

6.53e-0328812PS50929
DomainABC1_TM_dom

ABCC2 ABCB4

6.53e-0328812IPR011527
DomainZnF_U1

ZNF385D ZNF638

6.99e-0329812SM00451
DomainZnf_U1

ZNF385D ZNF638

6.99e-0329812IPR003604
DomainIQ_motif_EF-hand-BS

MYH9 ENKUR RASGRF2

7.04e-0390813IPR000048
DomainIQ

MYH9 ENKUR RASGRF2

7.71e-0393813PS50096
Domain-

LYVE1 CLEC3B PKD1L3

8.65e-03978133.10.100.10
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ERLIN2 EIF2S3 PSMC1 EIF2S3B ABCC2 ABCB4

1.61e-0699526MM14986
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ERLIN2 EIF2S3 PSMC1 ABCC2 ABCB4

3.74e-05103525M758
PathwayBIOCARTA_IGF1MTOR_PATHWAY

PIK3CA EIF2S3 EIF2S3B

5.16e-0520523MM1496
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYH9 ERLIN2 PDE6A SLC22A14 SYNE1 SMCHD1 UGGT1 KTN1 NFXL1 MAP7D2 MPHOSPH10 ZFC3H1 ABCC2 SMC2 PNISR CEP128 CAMSAP2 HDGFL2 HNRNPC ABCB4 ZNF292

2.18e-111442842135575683
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

RPL10A NCOR2 MYH9 VRK3 CELF1 BAZ2B SMCHD1 ZNF644 KTN1 ANKRD11 ZNF638 NFXL1 ZFC3H1 SMC2 PNISR HDGFL2 ESCO1 HNRNPC NOL8

2.02e-101294841930804502
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

RPL10A NCOR2 BAZ2B UTP11 EIF2S3 SMCHD1 ZNF644 KTN1 ANKRD11 ZNF638 SGO2 EIF2S3B MPHOSPH10 HDGFL2 HNRNPC NOL8

1.01e-09954841636373674
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

RPL10A ANK3 UBR5 EIF2S3 SYNE1 ZNF644 UGGT1 KTN1 APAF1 ANKRD11 NFXL1 MAP7D2 NUMB ZFC3H1 CACYBP TIMM44 HDGFL2 ARMC1 NOL8

2.03e-091487841933957083
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

NCOR2 MYH9 UBR5 EIF2S3 SYNE1 SMCHD1 ZNF638 PSMC1 EIF2S3B MPHOSPH10 CACYBP MORC2 FSCB

3.21e-08754841335906200
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

RPL10A AARS1 MYH9 UBR5 EIF2S3 SMCHD1 UGGT1 KTN1 ZNF638 PSMC1 EIF2S3B CACYBP CPS1 SMC2 TIMM44 HDGFL2 HNRNPC

4.03e-081415841728515276
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

RPL10A NCOR2 AARS1 RESF1 VRK3 ORC6 GON4L TIMM44 ZNF518A ZNF292

4.48e-08398841035016035
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NCOR2 AARS1 RESF1 CELF1 UBR5 BAZ2B ORC6 EIF2S3 SMCHD1 ZNF644 PSMC1 CACYBP MORC2 SMC2 ZNF292

5.75e-081103841534189442
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

RPL10A NCOR2 MYH9 UBR5 EIF2S3 KTN1 PSMC1 EIF2S3B SMC2 HDGFL2 HNRNPC

7.36e-08538841128524877
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RPL10A AARS1 MYH9 ERLIN2 EIF2S3 SYNE1 SMCHD1 UGGT1 KTN1 PSMC1 SGO2 CACYBP SMC2 TIMM44 DNAH5 HNRNPC

2.67e-071425841630948266
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

RPL10A CENPE EIF2S3 SMCHD1 KTN1 SGO2 ATG14 MPHOSPH10 ZFC3H1 SMC2 MTCH1 NOL8

2.88e-07759841235915203
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

AARS1 ERLIN2 ANK3 RASGRF2 CENPE KTN1 ANKRD11 MORC2 HDGFL2 ZNF292

3.48e-07497841036774506
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

RPL10A MYH9 CELF1 EIF2S3 SMCHD1 KTN1 APAF1 SMC2 CEP128 HNRNPC

3.55e-07498841036634849
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

UBR5 EIF2S3 APAF1 PSMC1 ACAA2 CPS1 MORC2 SMC2 TIMM44 DNAH5 HNRNPC

1.05e-06704841129955894
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

RESF1 BAZ2B ZNF644 ZFC3H1 MORC2 ZNF518A NOL8

1.17e-0622284737071664
Pubmed

Lysosomal Signaling Licenses Embryonic Stem Cell Differentiation via Inactivation of Tfe3.

RPL10A AARS1 VRK3 BAZ2B ZNF638 ZFC3H1 HNRNPC ZNF292

1.47e-0633284830595499
Pubmed

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.

ZNF638 SGO2 MPHOSPH10 HDGFL2 HNRNPC NOL8

1.66e-0614884632538781
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

RPL10A MYH9 UTP11 EIF2S3 SMCHD1 UGGT1 ZNF638 PSMC1 MPHOSPH10 ZFC3H1 CACYBP SMC2 HNRNPC NOL8

1.81e-061257841436526897
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

MYH9 VRK3 RASGRF2 UBR5 EIF2S3 UGGT1 PSMC1 SGO2 CLEC3B CACYBP SMC2 PKD1L3 HDGFL2 HNRNPC

2.31e-061284841417353931
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RPL10A AARS1 MYH9 EIF2S3 SMCHD1 KTN1 ZNF638 NUMB CACYBP CAMSAP2 HDGFL2 NOL8

2.51e-06934841233916271
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

VRK3 EIF2S3 SYNE1 KTN1 ANKRD11 PSMC1 GON4L NUMB MPHOSPH10 ZFC3H1 MORC2 PNISR CAMSAP2 HDGFL2 NOL8

2.72e-061497841531527615
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

ANK3 CENPE GCC2 SMCHD1 ZFC3H1 PNISR FCHO1 HNRNPC

2.74e-0636184826167880
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

RPL10A AARS1 MYH9 ERLIN2 ANK3 EIF2S3 SYNE1 UGGT1 KTN1 CACYBP HNRNPC

3.91e-06807841130575818
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RPL10A NCOR2 AARS1 MYH9 UBR5 SMCHD1 KTN1 ZNF638 PSMC1 NFXL1 ACAA2 SMC2 TIMM44 HNRNPC

4.23e-061353841429467282
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

RPL10A MYH9 ERLIN2 UBR5 GCC2 EIF2S3 PSMC1 CACYBP SMC2 MTCH1

4.25e-06657841036180527
Pubmed

Defining the membrane proteome of NK cells.

RPL10A NCOR2 AARS1 MYH9 ATP8A1 CELF1 CENPE UBR5 ORC6 GCC2 KTN1 PSMC1 NFXL1

4.44e-061168841319946888
Pubmed

ERLIN1 mutations cause teenage-onset slowly progressive ALS in a large Turkish pedigree.

ERLIN2 ABCC2

5.76e-06284229453415
Pubmed

The E3 ubiquitin ligase UBR5 interacts with TTC7A and may be associated with very early onset inflammatory bowel disease.

TTC7A UBR5

5.76e-06284233122718
Pubmed

Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease.

TTC7A UBR5

5.76e-06284224417819
Pubmed

Sexually dimorphic expression of the X-linked gene Eif2s3x mRNA but not protein in mouse brain.

EIF2S3 EIF2S3B

5.76e-06284216325480
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

RPL10A MYH9 ERLIN2 KTN1 ZNF638 MPHOSPH10 ZFC3H1 CPS1 SMC2 HNRNPC NOL8

6.17e-06847841135850772
Pubmed

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.

MYH9 ATP8A1 CELF1 EIF2S3 KTN1 PSMC1 SMC2 HNRNPC

7.08e-0641184836652389
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

RPL10A MYH9 ANK3 EIF2S3 KTN1 PSMC1 NUMB CACYBP SMC2 TIMM44

8.17e-06708841039231216
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

RPL10A NCOR2 MYH9 ERLIN2 VRK3 PIK3CA EIF2S3 KTN1 MPHOSPH10 CACYBP SMC2 CAMSAP2 HNRNPC

8.95e-061247841327684187
Pubmed

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

NCOR2 UBR5 ZNF644 SGO2 ZFC3H1

9.47e-0611684530804394
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

ERLIN2 CELF1 KTN1 NFXL1 MPHOSPH10 ZFC3H1 CACYBP MORC2 NOL8 ZNF292

9.92e-06724841036232890
Pubmed

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.

ZNF385D ANK3 SYNE1

1.28e-051984318711365
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

RPL10A ERLIN2 CENPE UTP11 SYNE1 ZNF644 KTN1 PSMC1 ACAA2 MPHOSPH10 CACYBP TIMM44 MTCH1 HNRNPC

1.32e-051496841432877691
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

RPL10A AARS1 MYH9 EIF2S3 KTN1 NFXL1 TIMM44 HDGFL2 HNRNPC

1.51e-0560184933658012
Pubmed

A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells.

RESF1 MORC2

1.73e-05384229728365
Pubmed

Proinflammatory signals and the loss of lymphatic vessel hyaluronan receptor-1 (LYVE-1) in the early pathogenesis of laminin alpha2-deficient skeletal muscle.

LYVE1 LAMA2

1.73e-05384220876525
Pubmed

Selected ABCB1, ABCB4 and ABCC2 polymorphisms do not enhance the risk of drug-induced hepatotoxicity in a Spanish cohort.

ABCC2 ABCB4

1.73e-05384224732756
Pubmed

ENKUR Is Involved in the Regulation of Cellular Biology in Colorectal Cancer Cells via PI3K/Akt Signaling Pathway.

ENKUR PIK3CA

1.73e-05384230947633
Pubmed

Knockdown of CEACAM19 suppresses human gastric cancer through inhibition of PI3K/Akt and NF-κB.

CEACAM19 PIK3CA

1.73e-05384230217308
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

TDRD15 MYH9 ERLIN2 ANK3 UBR5 CCDC146 GCC2 EIF2S3 ZNF638 NOL8

1.82e-05777841035844135
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

RPL10A AARS1 MYH9 ANK3 UBR5 EIF2S3 UGGT1 PSMC1 CACYBP SMC2 HDGFL2 HNRNPC

2.02e-051149841235446349
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

RPL10A MYH9 VRK3 EIF2S3 SMARCAL1 PSMC1 ACAA2 MORC2 HNRNPC

2.08e-0562684933644029
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

MYH9 UBR5 BAZ2B UGGT1 SGO2 SMC2

2.34e-0523584630258100
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCOR2 PDE6A ORC6 GCC2 SMARCAL1 KTN1 ATG14 MPHOSPH10 ZNF227

2.41e-0563884931182584
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

RPL10A MYH9 CELF1 UTP11 SYNE1 ZNF638 MPHOSPH10 PNISR HNRNPC NOL8

2.51e-05807841022681889
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

RPL10A AARS1 MYH9 EIF2S3 SMCHD1 KTN1 MAP7D2 CACYBP SMC2 HNRNPC

2.57e-05809841032129710
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

RESF1 NFXL1 LAMA2 ZNF292

2.72e-057184433541421
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

RPL10A MYH9 ERLIN2 SMCHD1 ZNF638 PSMC1 SGO2 SMC2 HNRNPC

2.85e-0565284931180492
Pubmed

P300 Interacted With N-Myc and Regulated Its Protein Stability via Altering Its Post-Translational Modifications in Neuroblastoma.

UBR5 PSMC1 SMC2

3.01e-052584336708875
Pubmed

Shugoshin-2 is essential for the completion of meiosis but not for mitotic cell division in mice.

CENPE SGO2

3.45e-05484218765791
Pubmed

PSAP induces a unique Apaf-1 and Smac-dependent mitochondrial apoptotic pathway independent of Bcl-2 family proteins.

APAF1 MTCH1

3.45e-05484223207240
Pubmed

Suppression of MEHMO Syndrome Mutation in eIF2 by Small Molecule ISRIB.

EIF2S3 EIF2S3B

3.45e-05484231836389
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

RPL10A MYH9 ERLIN2 ATP8A1 ANK3 EIF2S3 SYNE1 KTN1 PSMC1 MAP7D2 EIF2S3B CAMSAP2 HNRNPC

3.78e-051431841337142655
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

NCOR2 VRK3 UBR5 ZNF644 SMARCAL1 KTN1 NFXL1 CPS1 MORC2 SMC2

4.17e-05857841025609649
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

RPL10A AARS1 EIF2S3 SMCHD1 KTN1 NUMB TIMM44 HDGFL2 HNRNPC

5.57e-0571184933022573
Pubmed

Chemically synthesized cinobufagin suppresses nasopharyngeal carcinoma metastasis by inducing ENKUR to stabilize p53 expression.

MYH9 ENKUR

5.74e-05584235114328
Pubmed

ENKUR expression induced by chemically synthesized cinobufotalin suppresses malignant activities of hepatocellular carcinoma by modulating β-catenin/c-Jun/MYH9/USP7/c-Myc axis.

MYH9 ENKUR

5.74e-05584235414777
Pubmed

ENKUR recruits FBXW7 to ubiquitinate and degrade MYH9 and further suppress MYH9-induced deubiquitination of β-catenin to block gastric cancer metastasis.

MYH9 ENKUR

5.74e-05584236448053
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UBR5 STXBP5 GCC2 SYNE1 ZNF644 GON4L CAMSAP2

5.96e-0540784712693553
Pubmed

Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.

RPL10A MYH9 ERLIN2 UBR5 GCC2 EIF2S3 PSMC1

6.05e-0540884733766124
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

NCOR2 BAZ2B EIF2S3 ZNF638 TRIM71 CPS1 SMC2

6.34e-0541184735182466
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

RPL10A MYH9 ERLIN2 EIF2S3 UGGT1 KTN1 CPS1 SMC2 HNRNPC

6.47e-0572584927025967
Pubmed

Nucleolar proteome dynamics.

RPL10A MYH9 UTP11 EIF2S3 MPHOSPH10 SMC2 HNRNPC

7.15e-0541984715635413
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

RPL10A MYH9 VRK3 CELF1 EIF2S3 SMCHD1 PSMC1 MPHOSPH10 CACYBP SMC2 TIMM44 HNRNPC

7.59e-051318841230463901
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

RPL10A SMCHD1 KTN1 ANKRD11 ZNF638 PSMC1 ACAA2 MPHOSPH10 PNISR HNRNPC

7.66e-05922841027609421
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

NCOR2 MYH9 ORC6 SMCHD1 ZNF638 PSMC1 SMC2 HNRNPC

8.37e-0558284820467437
Pubmed

UTP11 deficiency suppresses cancer development via nucleolar stress and ferroptosis.

UTP11 MPHOSPH10

8.59e-05684237087976
Pubmed

The small molecule chemical compound cinobufotalin attenuates resistance to DDP by inducing ENKUR expression to suppress MYH9-mediated c-Myc deubiquitination in lung adenocarcinoma.

MYH9 ENKUR

8.59e-05684235296779
Pubmed

Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes.

SYNE1 HNRNPC

8.59e-05684221738484
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

MYH9 UBR5 UTP11 GCC2 UGGT1 MPHOSPH10 CEP128 MTCH1 NOL8

8.72e-0575484933060197
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

RPL10A MYH9 UTP11 EIF2S3 SYNE1 NUMB EIF2S3B MPHOSPH10 CPS1 HNRNPC

9.72e-05949841036574265
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

VRK3 BAZ2B SMCHD1 ZNF644 SGO2 MORC2 HDGFL2 ZNF292

1.13e-0460884836089195
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

RPL10A UBR5 UTP11 EIF2S3 SMCHD1 PSMC1 CACYBP SMC2 TIMM44 HNRNPC

1.17e-04971841033306668
Pubmed

Association of the X-chromosomal genes TIMP1 and IL9R with rheumatoid arthritis.

EIF2S3 CD40LG

1.20e-04784219723899
Pubmed

Boundaries between chromosomal domains of X inactivation and escape bind CTCF and lack CpG methylation during early development.

EIF2S3 EIF2S3B

1.20e-04784215669143
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

RPL10A AARS1 ERLIN2 UBR5 SMCHD1 UGGT1 PSMC1 EIF2S3B CACYBP SMC2

1.20e-04974841028675297
Pubmed

Functional specialization of beta-arrestin interactions revealed by proteomic analysis.

MYH9 UBR5 STXBP5 KTN1 HDGFL2 HNRNPC

1.22e-0431784617620599
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

MYH9 SMCHD1 UGGT1 ZNF638 ZFC3H1

1.34e-0420284524639526
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

RPL10A NCOR2 MYH9 UTP11 EIF2S3 SMCHD1 ZNF638 MPHOSPH10 HNRNPC NOL8

1.36e-04989841036424410
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

RPL10A AARS1 MYH9 EIF2S3 SYNE1 PSMC1 EIF2S3B SMC2 HNRNPC

1.40e-0480384936517590
Pubmed

Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.

RPL10A SMCHD1 SMC2 HNRNPC

1.45e-0410984429511296
Pubmed

Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling.

MYH9 ERLIN2 UBR5 EIF2S3B TIMM44 HNRNPC

1.57e-0433284629053956
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

RPL10A ERLIN2 CELF1 STXBP5 UGGT1 KTN1 NFXL1 MAP7D2 NUMB CACYBP

1.57e-041007841034597346
Pubmed

Sequential assembly of centromeric proteins in male mouse meiosis.

CENPE SGO2

1.60e-04884219283064
Pubmed

Regulation of membrane traffic by phosphoinositide 3-kinases.

PIK3CA ATG14

1.60e-04884216467569
Pubmed

Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study.

NUMB DNAH5

1.60e-04884217903303
Pubmed

Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism.

ABCC2 ABCB4

1.60e-04884211279518
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

CENPE UBR5 ZNF638 SGO2 MORC2

1.60e-0421084516565220
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

NCOR2 AARS1 MYH9 UBR5 SMCHD1 SMARCAL1 CACYBP MORC2 SMC2 HDGFL2

1.67e-041014841032416067
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

RPL10A MYH9 UTP11 EIF2S3 ZNF638 MPHOSPH10 NOL8

1.72e-0448384736912080
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RPL10A AARS1 MYH9 UBR5 SMCHD1 UGGT1 ZNF638 MPHOSPH10

1.84e-0465384822586326
Pubmed

N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.

ZNF644 SMARCAL1 ANKRD11 CAMSAP2 ZNF292

1.87e-0421784534048709
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

AARS1 MYH9 UGGT1 CPS1 SMC2 HNRNPC

1.91e-0434484630333137
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

BAZ2B KTN1 ATG14 ZFC3H1 MORC2 FCHO1 ESCO1

1.95e-0449384715368895
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

MYH9 ERLIN2 SMCHD1 ZNF644 PSMC1 ZNF518A ZNF292

2.00e-0449584727705803
InteractionDHX40 interactions

CELF1 UBR5 ZNF644 KTN1 ANKRD11 ZNF638 MPHOSPH10 ZFC3H1 PNISR HNRNPC NOL8

6.89e-092498411int:DHX40
InteractionSMC5 interactions

RPL10A NCOR2 MYH9 BAZ2B UTP11 EIF2S3 SMCHD1 ZNF644 KTN1 ANKRD11 ZNF638 SGO2 EIF2S3B MPHOSPH10 HDGFL2 HNRNPC NOL8

6.44e-0710008417int:SMC5
InteractionCEBPA interactions

NCOR2 AARS1 MYH9 RESF1 CELF1 UBR5 BAZ2B ORC6 EIF2S3 SMCHD1 ZNF644 PSMC1 CACYBP MORC2 SMC2 HDGFL2 HNRNPC ZNF292 NAA16

6.51e-0712458419int:CEBPA
InteractionCEBPB interactions

RPL10A NCOR2 AARS1 MYH9 VRK3 CELF1 EIF2S3 SMCHD1 ZNF644 KTN1 ZNF638 PSMC1 ACAA2 MPHOSPH10 CACYBP SMC2 TIMM44 HDGFL2 HNRNPC ZNF292

1.41e-0614438420int:CEBPB
InteractionDNAJC17 interactions

ZNF644 ANKRD11 ZFC3H1 HDGFL2 HNRNPC ARMC1 NOL8

1.45e-06134847int:DNAJC17
InteractionNUP43 interactions

NCOR2 ATP8A1 RESF1 UBR5 BAZ2B ZNF644 ANKRD11 GON4L MPHOSPH10 ZFC3H1 MORC2 ZNF518A ZNF292

1.80e-066258413int:NUP43
InteractionH3C1 interactions

RPL10A MYH9 ANK3 GCC2 SYNE1 SMCHD1 ZNF644 ZNF638 LAMA2 PWWP3B MORC2 TIMM44 HDGFL2 ESCO1 ZNF292

4.19e-069018415int:H3C1
InteractionBIRC3 interactions

RPL10A NCOR2 AARS1 MYH9 ERLIN2 EIF2S3 SYNE1 SMCHD1 UGGT1 KTN1 CD40LG PSMC1 SGO2 CACYBP SMC2 TIMM44 DNAH5 HNRNPC

7.66e-0613348418int:BIRC3
InteractionSNRNP40 interactions

NCOR2 UBR5 BAZ2B ZNF644 SMARCAL1 GON4L MPHOSPH10 ZFC3H1 PNISR HDGFL2 HNRNPC NOL8

1.27e-056378412int:SNRNP40
InteractionFBXO22 interactions

NCOR2 AARS1 ERLIN2 ANK3 RASGRF2 CENPE KTN1 ANKRD11 MORC2 HDGFL2 ZNF292

1.46e-055408411int:FBXO22
InteractionPOLR1G interactions

BAZ2B SMCHD1 ZNF644 ANKRD11 SGO2 MPHOSPH10 ZFC3H1 MORC2 NOL8 ZNF292

3.57e-054898410int:POLR1G
InteractionMYCN interactions

RPL10A MYH9 UTP11 EIF2S3 SYNE1 SMCHD1 UGGT1 KTN1 ZNF638 PSMC1 NUMB MPHOSPH10 ZFC3H1 CACYBP SMC2 HDGFL2 HNRNPC

4.31e-0513738417int:MYCN
InteractionMAPT interactions

RPL10A TTC7A AARS1 ERLIN2 ANK3 PIK3CA EIF2S3 KTN1 PSMC1 NUMB ACAA2 CACYBP CEP128 HNRNPC ARMC1

5.36e-0511198415int:MAPT
InteractionH2BC12 interactions

MYH9 CENPE SMCHD1 ANKRD11 ZNF638 MAP7D2 TIMM44 NOL8

5.92e-05322848int:H2BC12
InteractionAPEX1 interactions

MYH9 SMCHD1 ZNF644 SMARCAL1 KTN1 APAF1 ANKRD11 ZNF638 NUMB MORC2 SPOCD1 HDGFL2 FCHO1 HNRNPC NOL8 ZNF292

6.18e-0512718416int:APEX1
InteractionCAMSAP2 interactions

CELF1 ZNF638 MAP7D2 CEP128 CAMSAP2 HNRNPC

7.53e-05169846int:CAMSAP2
InteractionCASP4 interactions

MYH9 EIF2S3 APAF1 SMC2

7.58e-0554844int:CASP4
InteractionTFE3 interactions

RPL10A AARS1 VRK3 BAZ2B ZNF638 ZFC3H1 HNRNPC ZNF292

9.38e-05344848int:TFE3
InteractionH2BC4 interactions

MYH9 CENPE SMCHD1 ANKRD11 ZNF638 TIMM44 NOL8

1.04e-04259847int:H2BC4
InteractionPOLR1E interactions

BAZ2B UTP11 ZNF644 SGO2 MPHOSPH10 ZFC3H1 NOL8 ZNF292

1.06e-04350848int:POLR1E
InteractionSLX4 interactions

RESF1 UBR5 BAZ2B EIF2S3 SMCHD1 ZNF644 ZFC3H1 MORC2 ZNF518A NOL8

1.31e-045728410int:SLX4
InteractionZNF280D interactions

SMCHD1 ZNF644 ZNF292

1.33e-0424843int:ZNF280D
InteractionH2BC21 interactions

VRK3 SMCHD1 ZNF644 SMARCAL1 ZNF638 SGO2 SMC2 DNAH5 ESCO1 ZNF292 NAA16

1.45e-046968411int:H2BC21
InteractionDDX23 interactions

UBR5 SYNE1 ANKRD11 ZNF638 MPHOSPH10 MORC2 PNISR HDGFL2 NOL8

1.73e-04480849int:DDX23
InteractionCENPA interactions

SMCHD1 ZNF644 ANKRD11 SGO2 MORC2 HDGFL2 NOL8 ZNF292

1.76e-04377848int:CENPA
InteractionHECTD1 interactions

RPL10A CENPE EIF2S3 SMCHD1 KTN1 ANKRD11 SGO2 ATG14 MPHOSPH10 ZFC3H1 SMC2 MTCH1 NOL8

2.07e-049848413int:HECTD1
InteractionCDC5L interactions

MYH9 UBR5 ORC6 SYNE1 SMCHD1 SMARCAL1 ZNF638 PSMC1 SMC2 PNISR HNRNPC NOL8

2.14e-048558412int:CDC5L
InteractionRNF2 interactions

RPL10A ANK3 UBR5 EIF2S3 SYNE1 SMCHD1 ZNF638 NFXL1 SGO2 ATG14 MPHOSPH10 HNRNPC

2.41e-048668412int:RNF2
InteractionKCNA3 interactions

RPL10A MYH9 ANK3 EIF2S3 KTN1 PSMC1 NUMB CACYBP MORC2 SMC2 TIMM44 DNAH5

2.54e-048718412int:KCNA3
InteractionEGLN3 interactions

NCOR2 UBR5 ZNF644 UGGT1 ANKRD11 PSMC1 NFXL1 MAP7D2 NUMB SGO2 CACYBP SMC2 TIMM44 CAMSAP2 MTCH1

2.72e-0412968415int:EGLN3
InteractionEFTUD2 interactions

RPL10A MYH9 UBR5 EIF2S3 SMCHD1 UGGT1 KTN1 ZNF638 PSMC1 CACYBP CPS1 SMC2 TIMM44 ANKRD55 HDGFL2 HNRNPC

2.82e-0414498416int:EFTUD2
InteractionSRF interactions

NCOR2 RESF1 VRK3 ZNF518A ZNF292

2.90e-04139845int:SRF
InteractionMEN1 interactions

RPL10A MYH9 UBR5 SMCHD1 ZNF644 SMARCAL1 KTN1 ZNF638 MPHOSPH10 ZFC3H1 SMC2 HNRNPC NOL8

3.19e-0410298413int:MEN1
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

RESF1 CENPE BAZ2B PIK3CA GCC2 SMCHD1 ZNF644 KTN1 ZNF638 MPHOSPH10 SMC2 PNISR ARMC1

1.65e-076568413M18979
CoexpressionGSE17721_PAM3CSK4_VS_CPG_4H_BMDC_UP

NCOR2 AARS1 KATNBL1 SMARCAL1 ZNF638 CPS1 FCHO1

3.74e-06200847M3860
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

RPL10A MYH9 ATP8A1 RESF1 CELF1 UBR5 SYNE1 SMCHD1 ZNF644 KTN1 ANKRD11 ZNF638 ZFC3H1 CACYBP PNISR ZNF292

1.81e-0514928416M40023
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

CENPE UBR5 BAZ2B SMCHD1 ZNF638 NUMB PNISR CAMSAP2 ZNF292

1.86e-05466849M13522
CoexpressionTBK1.DF_DN

ERLIN2 KATNBL1 UGGT1 KTN1 ANKRD11 PNISR ARMC1

3.78e-05286847M2864
CoexpressionGSE18804_SPLEEN_MACROPHAGE_VS_BRAIN_TUMORAL_MACROPHAGE_DN

AARS1 ERLIN2 ORC6 ANKRD11 CACYBP ARMC1

4.17e-05197846M10015
CoexpressionGSE15659_RESTING_VS_ACTIVATED_TREG_DN

TTC7A ZNF385D UBR5 UGGT1 SGO2 ZFC3H1

4.29e-05198846M3563
CoexpressionGSE18804_SPLEEN_MACROPHAGE_VS_TUMORAL_MACROPHAGE_DN

AARS1 ERLIN2 ORC6 ANKRD11 LAMA2 MAP7D2

4.29e-05198846M10020
CoexpressionGSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_DN

ATP8A1 PIK3CA GCC2 SYNE1 ZFC3H1 PNISR

4.41e-05199846M7607
CoexpressionKIM_GERMINAL_CENTER_T_HELPER_UP

RESF1 ANKRD11 ZNF638 ZNF518A

5.39e-0564844M1405
CoexpressionBUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP

AARS1 RESF1 CELF1 BAZ2B PIK3CA ORC6 CDKL3 GON4L NUMB ATG14 PNISR

6.23e-058228411M6782
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

NCOR2 CENPE UBR5 BAZ2B GCC2 SMCHD1 ZNF638 NUMB PNISR CAMSAP2 ZNF292

8.94e-058568411M4500
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

CENPE UBR5 KTN1 ANKRD11 ZNF638 MAP7D2 SGO2 MPHOSPH10 SMC2 ESCO1 ZNF518A NOL8

1.04e-065328312Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

CENPE ANKRD11 ZNF638 SGO2 MPHOSPH10 SMC2 PNISR ZNF518A NOL8 ZNF292 NAA16

2.09e-064698311Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500_K1

RESF1 ANK3 CENPE ORC6 GCC2 SMCHD1 ZNF644 CDKL3 SGO2 PWWP3B MPHOSPH10 CACYBP SMC2 ZNF518A NOL8 ZNF292 NAA16

5.03e-0612418317facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_1000

MYH9 ANK3 PIK3CA ZNF644 APAF1 SMC2 PNISR CAMSAP2 ZNF292

1.58e-05375839gudmap_developingKidney_e15.5_cortic collect duct_1000_k4
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

RESF1 VRK3 CENPE ORC6 GCC2 ZNF644 ZNF638 SGO2 PWWP3B MPHOSPH10 CACYBP SMC2 CEP128 ZNF518A ZNF292 NAA16

2.36e-0512528316facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

CENPE ORC6 GCC2 SMCHD1 ZNF644 KTN1 SGO2 PWWP3B MPHOSPH10 CACYBP SMC2 PNISR CEP128 NOL8 ZNF292 NAA16

2.48e-0512578316facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

ATP8A1 CENPE UBR5 GCC2 EIF2S3 KTN1 MAP7D2 TRIM71 MPHOSPH10 CACYBP PNISR ZNF518A NOL8 ZNF292

2.71e-059898314Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_500

KATNBL1 ATP8A1 RESF1 CENPE ANKRD11 TRIM71 SMC2 PNISR ESCO1

2.78e-05403839gudmap_developingGonad_e12.5_epididymis_500
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500

RESF1 ANK3 CENPE ORC6 GCC2 SMCHD1 ZNF644 CDKL3 SGO2 PWWP3B MPHOSPH10 CACYBP SMC2 ZNF518A NOL8 ZNF292 NAA16

4.42e-0514688317facebase_RNAseq_e10.5_MandArch_2500
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_1000

MYH9 RESF1 ANK3 RASGRF2 CENPE ANKRD11 SMC2 CAMSAP2

5.41e-05339838gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

ATP8A1 CENPE UBR5 STXBP5 KTN1 GON4L MAP7D2 MPHOSPH10 PNISR ZNF518A NOL8 ZNF292

8.98e-058318312Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5

CENPE GCC2 ZNF638 MAP7D2 SGO2 SMC2

8.99e-05186836Facebase_RNAseq_e10.5_Mandibular Arch_500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3

CENPE UBR5 KTN1 MAP7D2 MPHOSPH10 NOL8

1.07e-04192836Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

CENPE ORC6 GCC2 SMCHD1 ZNF644 KTN1 SGO2 PWWP3B MPHOSPH10 CACYBP SMC2 PNISR CEP128 NOL8 ZNF292 NAA16

1.46e-0414598316facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_1000

MYH9 ATP8A1 ANK3 RASGRF2 PIK3CA ZNF644 APAF1 SMC2 PNISR CAMSAP2 ZNF292

2.08e-047748311gudmap_developingKidney_e15.5_cortic collect duct_1000
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000

KATNBL1 ATP8A1 RESF1 CENPE ANKRD11 ZNF638 TRIM71 SMC2 PNISR ESCO1 NOL8

2.94e-048068311gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_500

KATNBL1 CENPE ANKRD11 SMC2 PNISR

3.07e-04150835gudmap_developingGonad_e12.5_epididymis_k5_500
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#5_top-relative-expression-ranked_1000

MYH9 BAZ2B MPHOSPH10 SMC2 CAMSAP2

3.26e-04152835gudmap_developingKidney_e15.5_S-shaped body_1000_k5
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

RESF1 ANK3 GCC2 EIF2S3 SMCHD1 ANKRD11 ZNF638 ZFC3H1 PNISR ANKRD55 NAA16

1.08e-131958411d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANK3 GCC2 SYNE1 SMCHD1 ANKRD11 ZFC3H1 PNISR ZNF292

3.84e-0919784857ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANK3 SYNE1 SMCHD1 ZNF644 ANKRD11 ZFC3H1 PNISR ZNF292

4.16e-09199848f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYVE1 MYH9 RESF1 KTN1 NFXL1 NUMB ZFC3H1

3.88e-08173847869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYVE1 MYH9 RESF1 KTN1 NFXL1 NUMB ZFC3H1

3.88e-081738470672bd8a4a9d18af343d01f09253fb3388896c10
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYVE1 MYH9 RESF1 KTN1 NFXL1 NUMB ZFC3H1

3.88e-08173847870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCellnormal-na-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

RPL10A LYVE1 RESF1 GCC2 SMCHD1 CD40LG PNISR

4.72e-08178847fa3585383a1e7da460c88a802aaa81246d681b6b
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated|bone_marrow / Manually curated celltypes from each tissue

ANK3 RASGRF2 EIF2S3 CD40LG CACYBP MORC2 ANKRD55

6.38e-081868475108d9b7a081876ca34594b110d58df56063f542
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH9 RESF1 CENPE SMCHD1 CD40LG SGO2 SMC2

7.65e-08191847912e2d10d3423aa7f708fcf2b11da1845f12d7d3
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH9 RESF1 CENPE SMCHD1 CD40LG SGO2 SMC2

7.65e-0819184777a2746b6d9c53b08d4405411c16fcc5a6c734ce
ToppCellnormal-na-Lymphocytic_T-T4_naive-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

RPL10A RESF1 ANK3 GCC2 EIF2S3 SMCHD1 PNISR

9.12e-08196847feb1c768cf66c64b6c892905d2d865946e70812f
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ATP8A1 RESF1 ANK3 GCC2 SMCHD1 CD40LG ZNF292

9.12e-081968474a880a5d2c7047c050c7d6dd62186f35dc5c01f7
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

CCDC146 BAZ2B GCC2 KTN1 ANKRD11 DNAH5 ZNF292

1.01e-07199847fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RESF1 SMCHD1 ZNF644 ANKRD11 ZFC3H1 PNISR ZNF292

1.05e-0720084712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD4+_T_activated|COVID-19_Severe / Disease, condition lineage and cell class

RPL10A RESF1 ANK3 RASGRF2 GCC2 SMCHD1 CD40LG

1.05e-07200847deeed668b129e66156b5f6abe1a07a9bf842a14d
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH9 RESF1 KTN1 NFXL1 NUMB ZFC3H1

1.00e-061758461ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LYVE1 CENPE ORC6 SGO2 SMC2 ABCB4

1.07e-061778468a74f5e72de605774111057bd87a7e7e4a6385cd
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-CD4-positive_helper_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RPL10A ANK3 GCC2 EIF2S3 CD40LG ANKRD55

1.52e-06188846f7dd01084ad14d2a2d8adf552e811b84eebf5514
ToppCellCOVID-19-T_cells-CD4+_T_cells|COVID-19 / group, cell type (main and fine annotations)

ATP8A1 RESF1 ANK3 RASGRF2 SMCHD1 CD40LG

1.67e-061918460646cca78e24aeb6baa9934d3c439b797c567997
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

UBR5 GCC2 ZNF638 ZFC3H1 PNISR ZNF292

1.72e-06192846916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPL10A RESF1 ANK3 GCC2 SMCHD1 CD40LG

1.77e-061938462901d7a9672a8cf70c9f1c752685b45e4d79ac70
ToppCellHealthy/Control-CD4+_T_naive|Healthy/Control / Disease group and Cell class

RPL10A ANK3 RASGRF2 GCC2 CD40LG ANKRD55

1.77e-06193846f5face746df3517c86d72e31ba8f1b78c4c6b481
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPL10A RESF1 ANK3 GCC2 SMCHD1 CD40LG

1.77e-06193846f4310faa13fc8ce99a217e2d1c9cc733683797a1
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

UBR5 GCC2 ZNF638 ZFC3H1 PNISR ZNF292

1.77e-06193846e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RPL10A RESF1 ANK3 GCC2 SMCHD1 CD40LG

1.77e-06193846f8af695457d2a0a911a5ac491742465864ebda37
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

RPL10A RESF1 ANK3 GCC2 SMCHD1 CD40LG

1.77e-06193846089aece40130034a89a5213be778f10b0787eeba
ToppCellsevere-CD4+_Tcm|severe / disease stage, cell group and cell class

RPL10A ANK3 GCC2 CD40LG PNISR ANKRD55

1.83e-06194846380fbd19b72af6767f98bbf50329686b76d59c54
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RPL10A RESF1 ANK3 GCC2 CD40LG ANKRD55

1.88e-0619584607035a5972a78b98e4ab2167e3a5000f9f3b0826
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RPL10A RESF1 ANK3 GCC2 CD40LG ANKRD55

1.88e-061958465001e68df2ad5df9dc93ae235f984ffafea6b521
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH9 ANK3 SYNE1 SMCHD1 ZNF227 CACYBP

1.94e-06196846ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

CENPE ZNF638 ZFC3H1 PNISR NOL8 ZNF292

2.00e-061978460fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

RESF1 CCDC146 GCC2 ZNF644 KTN1 ANKRD11

2.12e-0619984661b1ed2db71b96157b92b7535d1955a4033098da
ToppCellmild-CD4+_T_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RESF1 ANK3 RASGRF2 GCC2 PNISR ANKRD55

2.12e-061998463e4baaf4ee23f257d821194468102c00a8ad2f21
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

BAZ2B GCC2 ZNF644 KTN1 ANKRD11 ZNF292

2.12e-06199846c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

ATP8A1 RESF1 GCC2 SYNE1 SMCHD1 PNISR

2.12e-06199846952fac67588ad5676f5939e3c7f8bac803c27064
ToppCell10x5'-Liver-Lymphocytic_T_CD4-Tfh|Liver / Manually curated celltypes from each tissue

ERLIN2 ANK3 CD40LG CAMSAP2 ANKRD55

1.16e-0515684585bc34ff507f9a66c6e3ba7a3ffd5416d0073ccf
ToppCelldroplet-Heart-nan-3m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 GCC2 CDKL3 NUMB ESCO1

1.20e-05157845d85a2f56ae313baa9738e81d2756ce1fe1ba50db
ToppCellnormal-na-Lymphocytic_T-T4_em-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

RESF1 ANK3 GCC2 SMCHD1 CD40LG

1.81e-0517184561318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell356C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LYVE1 ANK3 ORC6 SGO2 SMC2

1.81e-05171845b113fbebb89056af0b9c775d2fb6552206a80467
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF385D ATP8A1 ANK3 CPXM2 PNISR

1.92e-051738450c74bdb40e635d906fd180412c23bf7fed61621e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF385D CENPE SGO2 SMC2 CEP128

2.02e-05175845876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCellCOVID-19-kidney-PCT-S3-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

TDRD15 GBP7 ABCC2 CPS1 ABCB4

2.08e-05176845b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EIF2S3 SYNE1 CD40LG ANKRD55 FCHO1

2.14e-0517784564b8f665fdaf975558af2ad7d9b54d206de8350c
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 SYNE1 SMCHD1 KTN1 ANKRD11

2.20e-0517884501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF385D CENPE ORC6 SGO2 SMC2

2.38e-0518184573b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE SYNE1 SGO2 SMC2 CEP128

2.44e-051828459025178ede571e3808d4657ad4892152f336c9b4
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE SYNE1 SGO2 SMC2 CEP128

2.44e-05182845c075756cd4bb484ede1be2bcdb9eac60eab0573a
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL10A BAZ2B SMCHD1 KTN1 ESCO1

2.51e-0518384528cbf909424f3be4491d49832f0aca0386560814
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL10A BAZ2B SMCHD1 KTN1 ESCO1

2.51e-051838453fa608aa6b119869ec3280dc388dfee57160e63a
ToppCellnormal-na-Lymphocytic_T-T8_naive-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

RESF1 GCC2 EIF2S3 PNISR NAA16

2.57e-051848454a81190b36d197736663e6177d3b76c1cb6282d6
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCC2 SMCHD1 KTN1 ANKRD11 ZNF638

2.57e-051848451154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANK3 RASGRF2 GCC2 CD40LG ANKRD55

2.57e-051848455350b58aa9979631228835d11eb45ddf81d08bff
ToppCellCOVID-CD4-naive_CD4|COVID / Condition, Cell_class and T cell subcluster

ANK3 SMCHD1 CD40LG ABCC2 ANKRD55

2.57e-0518484500db55970d336a301035efe43a4ab4db62627f38
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL10A MYH9 CENPE ANKRD11 CPS1

2.71e-0518684515ab6666748a641226e42e6ca6eeaf186a501c95
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL10A MYH9 CENPE ANKRD11 CPS1

2.71e-051868454ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CENPE ORC6 SGO2 SMC2 CEP128

2.78e-05187845057569c9437219ecc396aa6e673b1178a2273837
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

RESF1 ANK3 GCC2 CD40LG ANKRD55

2.85e-05188845b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCell(04)_Pre-ciliated-(3)_72hpi|(04)_Pre-ciliated / shred by cell type and Timepoint

ENKUR CCDC146 CEP128 DNAH5 HDGFL2

2.85e-05188845f911dc61b008b60aaa2a1e9354085f480a669e2c
ToppCelldroplet-Tongue-nan-24m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RESF1 CENPE ORC6 CLEC3B SMC2

2.93e-05189845258ef4a52f90236dbed92f325ca033c8fa6156a5
ToppCellIPF-Lymphoid-T|IPF / Disease state, Lineage and Cell class

MYH9 ATP8A1 ANK3 SMCHD1 CD40LG

3.00e-05190845d57df208aaf7a5554899bb9107c80b443fd0cf93
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RPL10A GCC2 CD40LG PNISR ANKRD55

3.08e-05191845f398344aaa79fc93d792e241b634a6afe4aff33d
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

PIK3CA SMCHD1 ZNF644 MTCH1 ZNF292

3.08e-051918451ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCellCOVID-19-kidney-Proliferating_T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

CENPE ORC6 SGO2 SMC2 CEP128

3.08e-05191845bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPL10A GCC2 CD40LG PNISR ANKRD55

3.08e-0519184511da47d96f44ba629e3299667495e7daddbbe86c
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RPL10A GCC2 CD40LG PNISR ANKRD55

3.08e-05191845ffcb2c8dbcf40281b439f4b719b5b341972ffb9a
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPL10A GCC2 CD40LG PNISR ANKRD55

3.08e-05191845ffe88d1ad676c745c76db89f766062fd365329f4
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CENPE CD40LG PSMC1 CACYBP SMC2

3.16e-05192845694626965faee8b7c4e5bb78d554f62ba8dbc423
ToppCellCOPD-Lymphoid-T|World / Disease state, Lineage and Cell class

MYH9 ATP8A1 ANK3 SMCHD1 CD40LG

3.16e-05192845eb4909574fb5fc91399463523e2737095773200a
ToppCellCOVID-19_Convalescent-Lymphoid_T/NK-CD4+_T_naive|COVID-19_Convalescent / Disease group, lineage and cell class

RPL10A GCC2 CD40LG PNISR ANKRD55

3.16e-05192845ad7207810116e73d461242e42071901b6a9f48c6
ToppCellremission-CD4+_T_naive|remission / disease stage, cell group and cell class

RPL10A GCC2 CD40LG PNISR ANKRD55

3.16e-05192845d96b2122e28c735d8002ad6eb2d3d52c8e9ccf2b
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RESF1 ANK3 GCC2 SMCHD1 CD40LG

3.16e-05192845e07b6892276c81c1227e94ca942f6820d89a7ca3
ToppCellremission-CD4+_T_naive|World / disease stage, cell group and cell class

RPL10A GCC2 CD40LG PNISR ANKRD55

3.16e-051928454bd94ce876d70f93dbdfad1dcd09e1468213cf57
ToppCellHealthy/Control-CD4+_T_naive|World / Disease group and Cell class

RPL10A ANK3 RASGRF2 GCC2 CD40LG

3.23e-051938456218e6cbe44d92bb98d42ef2f5e18ab7a683b100
ToppCellCOVID-19_Severe-Lymphoid_T/NK-CD4+_T_activated|COVID-19_Severe / Disease group, lineage and cell class

RPL10A RESF1 ANK3 GCC2 CD40LG

3.23e-05193845beb862d38b88572836b0a797c8efef7a2492e0b9
ToppCellmild_COVID-19-CD4+_T_naive|World / disease group, cell group and cell class (v2)

RPL10A ANK3 GCC2 CD40LG ANKRD55

3.23e-0519384542ddacc55658ea6ba4248ac19c9c3709f342b4f5
ToppCelldroplet-Tongue-nan-24m-Epithelial-proliferating|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE ORC6 SGO2 CLEC3B SMC2

3.23e-05193845f20b90e3f3f5c9a1ae51c5ebe6d3adb954a142f2
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CENPE ORC6 SGO2 ACAA2 SMC2

3.32e-0519484517af04acd54dd6a895a966cbb4422de25dc4f1e6
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CENPE ORC6 SGO2 ACAA2 SMC2

3.32e-051948453c385d93c5fe1a7817813c492f79fdb94d887357
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RESF1 ANK3 GCC2 SMCHD1 CD40LG

3.32e-051948450b0042b6a356a49a059fb64a1e1abb25c82d48cf
ToppCellHealthy_donor-CD4+_T_naive|Healthy_donor / disease group, cell group and cell class (v2)

RPL10A ANK3 GCC2 CD40LG ANKRD55

3.32e-05194845a8a0368a4e0eb5654fdffc8a779b08ad402aa2eb
ToppCellsevere_COVID-19-CD4+_T_naive|severe_COVID-19 / disease group, cell group and cell class (v2)

RPL10A ANK3 RASGRF2 GCC2 ANKRD55

3.32e-051948454b86f3cc173ea779399d5b3598b45b25f60a4395
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

RPL10A GCC2 CD40LG PNISR ANKRD55

3.32e-0519484531a98ce929ee6cf6a9747e384f9a06336af49fd5
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CENPE ORC6 SGO2 ACAA2 SMC2

3.32e-05194845635d0e88f9c542a1d9363066c6cdbc6e44db76c1
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LYVE1 CENPE ORC6 SGO2 SMC2

3.32e-051948453a49c7c86036e09a8cd0114988380d04ad1a26fb
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPL10A GCC2 CD40LG PNISR ANKRD55

3.32e-0519484589e30624e389ff7b4a3b6e02d2b77cdeae263ded
ToppCellCOVID-19_Mild-Lymphoid_T/NK-CD4+_T_naive|COVID-19_Mild / Disease group, lineage and cell class

RPL10A ANK3 GCC2 CD40LG ANKRD55

3.40e-051958458aec807b24bcebf1a8011d676d2143b6fc570f1d
ToppCellCOVID-19-kidney-Proliferating_T_cell|kidney / Disease (COVID-19 only), tissue and cell type

CENPE ORC6 CD40LG SGO2 SMC2

3.40e-051958457e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPL10A ANK3 GCC2 CD40LG ANKRD55

3.40e-05195845d9965223430aba1ec0b1b77b5bd40d3a01e42e95
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RPL10A ANK3 GCC2 CD40LG ANKRD55

3.40e-05195845d056c806c7ad38ca425bdaa44385424a7f43f915
ToppCellCOVID-19_Moderate-CD4+_T_naive|World / disease group, cell group and cell class

RPL10A ANK3 GCC2 CD40LG ANKRD55

3.40e-0519584538d65cf0895f7a99d789ec3dcbd56a7506706d38
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CENPE ORC6 SGO2 SMC2 CEP128

3.40e-05195845926eb3fc5d028be936885bea0654a77db3107234
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LYVE1 CENPE GCC2 SGO2 SMC2

3.40e-05195845eca24039bde02f4677f1f89a373f501c649ec2a5
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPL10A ANK3 GCC2 CD40LG ANKRD55

3.40e-051958451d3c51a3be5ad1fbc465c5f684565ec4c6f35f54
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CENPE ORC6 SGO2 SMC2 CEP128

3.40e-051958451a5e814e12fe37287dbfc58189e1958e2c76b5da
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

RESF1 ANK3 GCC2 SMCHD1 CD40LG

3.40e-0519584522191d361af136942508f1553ff41a626ed982ad
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RPL10A RESF1 SMCHD1 CD40LG ANKRD55

3.40e-051958458ae2886dd4cfc70c58b61fbb6994f0a22f8c9127
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

RPL10A ANK3 GCC2 CD40LG ANKRD55

3.40e-051958456421d949bfebcd985bea7efc5731a1ca79350b61
ToppCell367C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MYH9 RESF1 SMCHD1 CD40LG ANKRD55

3.48e-0519684585684b881655e47f06f0cf00721183825fa00913
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

RPL10A ANK3 GCC2 CD40LG ANKRD55

3.48e-05196845ffc2728663a72ec62fa2e5b1054368fb56d18c62
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CENPE ORC6 SGO2 SMC2 CEP128

3.48e-051968451d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

MYH9 RESF1 GCC2 SYNE1 SMCHD1 ANKRD11 ZNF292

4.50e-0949557GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
DrugClorgyline

BAZ2B GCC2 SMCHD1 ZNF644 KTN1 ZNF638 ESCO1 ZNF292

1.83e-07168838ctd:D003010
DrugTolnaftate [2398-96-1]; Up 200; 13uM; HL60; HG-U133A

ERLIN2 CELF1 KTN1 APAF1 CAMSAP2 ZNF292 NAA16

8.30e-061998372001_UP
Diseaseosteoarthritis, knee, body mass index

AARS1 CPS1 PKD1L3 HNRNPC

5.19e-0641824EFO_0004340, EFO_0004616
DiseaseMEHMO syndrome (implicated_via_orthology)

EIF2S3 EIF2S3B

7.63e-062822DOID:0060801 (implicated_via_orthology)
Diseasecolon adenocarcinoma (is_implicated_in)

UBR5 PIK3CA SMC2

5.14e-0526823DOID:234 (is_implicated_in)
DiseaseTesticular Germ Cell Tumor

RESF1 CENPE ZNF638 ATG14

5.21e-0573824EFO_1000566
Diseasehypopituitarism (implicated_via_orthology)

EIF2S3 EIF2S3B

1.14e-046822DOID:9406 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

MYH9 RASGRF2 PIK3CA SYNE1 ZNF644 SMARCAL1 KTN1 LAMA2 MAP7D2 SPOCD1 FSCB

1.86e-0410748211C0006142
DiseaseCholestasis of pregnancy

ABCC2 ABCB4

2.11e-048822C0268318
Diseasefibrinogen measurement, tissue plasminogen activator measurement

STXBP5 CPS1 PKD1L3

2.70e-0445823EFO_0004623, EFO_0004791
Diseaseleukodystrophy (implicated_via_orthology)

EIF2S3 EIF2S3B

2.71e-049822DOID:10579 (implicated_via_orthology)
Diseasecholestasis (implicated_via_orthology)

ABCC2 ABCB4

2.71e-049822DOID:13580 (implicated_via_orthology)
DiseaseX-21467 measurement

ABCC2 CPS1

2.71e-049822EFO_0020007
Diseasefactor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement

STXBP5 CPS1 PKD1L3

5.16e-0456823EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
DiseaseFetal Alcohol Spectrum Disorders

ANK3 PIK3CA

5.83e-0413822C2985290
DiseaseX-24588 measurement

NUMB ABCC2

5.83e-0413822EFO_0800898
Diseaselean body mass

NCOR2 KTN1 ZNF638 LAMA2 CPS1 HNRNPC

6.65e-04379826EFO_0004995
DiseaseColorectal Carcinoma

ZNF385D RASGRF2 PIK3CA SYNE1 ABCC2 CAMSAP2 ABCB4 ZNF292

7.48e-04702828C0009402
Diseasemyopia (is_implicated_in)

ZNF644 LAMA2

8.93e-0416822DOID:11830 (is_implicated_in)
DiseaseBenign neoplasm of stomach

UBR5 PIK3CA

1.01e-0317822C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

UBR5 PIK3CA

1.01e-0317822C0496905
Diseasemuscular dystrophy (is_implicated_in)

SYNE1 LAMA2

1.01e-0317822DOID:9884 (is_implicated_in)
DiseaseCarcinoma in situ of stomach

UBR5 PIK3CA

1.01e-0317822C0154060
DiseaseFetal Alcohol Syndrome

ANK3 PIK3CA

1.01e-0317822C0015923
Diseasetissue plasminogen activator measurement, coronary artery disease

TDRD15 STXBP5 FCHO1

1.03e-0371823EFO_0001645, EFO_0004791
DiseaseColorectal Neoplasms

PIK3CA SYNE1 ABCC2 ABCB4 ZNF292

1.06e-03277825C0009404
DiseaseChronic myeloproliferative disorder

CENPE ORC6

1.27e-0319822C1292778
Diseasefatty acid measurement

ZNF385D TDRD15 ACAA2 CEP128 ESCO1 HNRNPC

1.37e-03436826EFO_0005110
DiseaseStomach Carcinoma

UBR5 PIK3CA

1.55e-0321822C0699791
DiseaseSeckel syndrome

CENPE ORC6

1.70e-0322822C0265202
DiseaseNasopharyngeal carcinoma

PIK3CA SYNE1

1.70e-0322822C2931822
Diseasecholesteryl ester measurement, high density lipoprotein cholesterol measurement

TDRD15 NCOR2 CELF1 CPS1 HNRNPC

1.80e-03312825EFO_0004612, EFO_0010351
Diseasefree cholesterol measurement, high density lipoprotein cholesterol measurement

TDRD15 NCOR2 CELF1 CPS1 HNRNPC

1.87e-03315825EFO_0004612, EFO_0008591
Diseasetotal cholesterol measurement, high density lipoprotein cholesterol measurement

TDRD15 NCOR2 CELF1 CPS1 HNRNPC

1.87e-03315825EFO_0004574, EFO_0004612
Diseasephospholipid measurement, high density lipoprotein cholesterol measurement

TDRD15 NCOR2 CELF1 ACAA2 CPS1

2.03e-03321825EFO_0004612, EFO_0004639
Diseaseapolipoprotein L1 measurement

MYH9 PKD1L3

2.20e-0325822EFO_0021854
Diseasepain

LAMA2 CPS1 PKD1L3 HNRNPC

2.20e-03196824EFO_0003843
Diseaselipid measurement, high density lipoprotein cholesterol measurement

TDRD15 NCOR2 CELF1 ACAA2 CPS1

2.29e-03330825EFO_0004529, EFO_0004612
DiseaseAlzheimer disease

VRK3 ANK3 CELF1 CLEC3B CPS1 ANKRD55

2.34e-03485826MONDO_0004975
Diseaseergothioneine measurement

CPS1 DNAH5

2.37e-0326822EFO_0021163
Diseaseosteoarthritis (is_implicated_in)

NCOR2 CLEC3B

2.75e-0328822DOID:8398 (is_implicated_in)
Diseaseglucose metabolism disease (implicated_via_orthology)

EIF2S3 EIF2S3B

2.75e-0328822DOID:4194 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
LEAMKNKQKSVTAKD

ZNF385D

111

Q9H6B1
KTDAVAEMKAVSKNK

BHLHB9

51

Q6PI77
TKKVCKNSAVMLKQE

APAF1

911

O14727
KKQSKIQSQMKVEKA

CEP128

596

Q6ZU80
MVEKQTGKKDKDKVS

ANKRD11

21

Q6UB99
NKEETKKENSFEMQK

CD40LG

101

P29965
KSKQEEFQKEVLKAM

ATG14

86

Q6ZNE5
MVVKFADTQKDKEQK

CELF1

181

Q92879
KQQAIMAAEEKRKQK

BAZ2B

921

Q9UIF8
IQSKDTKGMEVKQIK

CDKL3

531

Q8IVW4
ASTKVMKAQQVVKSE

ARMC1

201

Q9NVT9
VAMVEFKKKTSDNSK

ANKRD55

401

Q3KP44
KSEVVEMVKKQVKVV

ATP8A1

781

Q9Y2Q0
NKKVMRTKSSEKAAN

CPXM2

106

Q8N436
TSQKEMDKAETKTKK

FCHO1

156

O14526
KLTESNSAMVKSKKQ

NCOR2

2271

Q9Y618
NSAMVKSKKQEINKK

NCOR2

2276

Q9Y618
RKKISNFTNKNMKEV

KATNBL1

26

Q9H079
KIEKEQSKQAVEMKN

HNRNPC

216

P07910
EQVEMKAKVVQSEVK

TRIM71

351

Q2Q1W2
KNQQKEMIETKVVKE

LYVE1

271

Q9Y5Y7
MSQKKFEEIKKANQA

NFXL1

81

Q6ZNB6
KAMIEKQKEAAETKA

MAP7D2

501

Q96T17
MVGKSQQTDVIEKKK

FSCB

1

Q5H9T9
KKRTMFQKIVDQSKT

PDE6A

676

P16499
KVLSQEMQKIFVKKD

NAA16

731

Q6N069
AEKSKIETEIKNKMQ

CACYBP

31

Q9HB71
VKSSFEKRQEKMNEK

MPHOSPH10

356

O00566
TEKMLQDKVNKTSKE

KTN1

1046

Q86UP2
SQEFQKKLVDTMEKK

GBP7

376

Q8N8V2
VNQKNMTALEKKKEA

LAMA2

1806

P24043
STKSKTIQVKNMKNK

ABCC2

481

Q92887
KATDKSFVEKVMQEQ

MYH9

536

P35579
TDEIIAMKKNVAKVK

NOL8

381

Q76FK4
AMKKNVAKVKNSTEF

NOL8

386

Q76FK4
VAKVKNSTEFSQMEK

NOL8

391

Q76FK4
EAVQKVNKAGMEKEK

HDGFL2

556

Q7Z4V5
QEKKDETQKVQMKFL

PIK3CA

721

P42336
QKVMEKETEKKISEI

ERLIN2

231

O94905
NVTMDEIKKAVKEAN

ABCB4

496

P21439
RKDMKTQEEKQKQLT

MORC2

551

Q9Y6X9
SQAVKAMKEENVKTV

CPS1

446

P31327
KKENIKMKQEVEDSV

GCC2

96

Q8IWJ2
MKKSSAKQLQEVEKV

GON4L

656

Q3T8J9
SIKEKVKAFQMKASS

ANK3

2211

Q12955
ASKMKQVSQSEKTKA

ANK3

3886

Q12955
TMKAKTEVQVAEKNK

CEACAM19

131

Q7Z692
FKATVKDDMQKAKTA

ENKUR

31

Q8TC29
VKKESSQMESVKEEK

ESCO1

321

Q5FWF5
KAAKVQKLSKNEVLM

EIF2S3B

391

Q2VIR3
QIRNKVKDMKTKETS

SLC22A14

576

Q9Y267
EAQKKKMEAAFTKQR

CAMSAP2

776

Q08AD1
ENTKEIVAKMKESQE

CENPE

1611

Q02224
KKDVNETQKKVSEME

CENPE

1836

Q02224
ETQKKVSEMEQLKKQ

CENPE

1841

Q02224
TMKAQAAEKVKAEVQ

DNAH5

3246

Q8TE73
KQMQDAKKAETDKIV

NUMB

211

P49757
VSNKDDMKTSLKKVV

MTCH1

181

Q9NZJ7
MDKTQKVKVKKETVN

UTP11

226

Q9Y3A2
DVKKQQQMAALTKEK

SMCHD1

1616

A6NHR9
MVSQVKDFVKKLQSK

SYNE1

4171

Q8NF91
MLNSESKNKVNIKKV

TDRD15

681

B5MCY1
KENKNKIDISAVMSV

PWWP3B

206

Q5H9M0
SKQTKALMDKLQKTV

RASGRF2

1116

O14827
KEKMVSNTKSVDTKA

RESF1

1421

Q9HCM1
AKEMTTKDKTKQQQK

SMARCAL1

681

Q9NZC9
KDQADMQKVKVTVLA

PKD1L3

721

Q7Z443
ECQVKKVNKMTSKSK

SGO2

1066

Q562F6
VDKNKMVATSGVKKA

ORC6

156

Q9Y5N6
RMKVTNEDFKKSKEN

PSMC1

411

P62191
EQKMNNFIEKVKTKS

STXBP5

726

Q5T5C0
MTQIKIDEKEQKSKD

CCDC146

461

Q8IYE0
IVSKLQEMKEKKEAQ

CCDC146

591

Q8IYE0
IEVKTKKGKQTMQVD

ACAA2

206

P42765
KKCLSVMEAKVKAQT

AARS1

771

P49588
IVNAKKDVVNTKMFE

CLEC3B

31

P05452
GKVQKMVSFNSKVEK

SPOCD1

1031

Q6ZMY3
KKQLAMTEENKKESQ

ZNF292

2006

O60281
NTEDIMKQKQKFVDK

VRK3

396

Q8IV63
QVLKKMNKTQTKSED

ZNF518A

346

Q6AHZ1
AKVDEVKSTIKFQMK

RPL10A

146

P62906
DASSKKMKEKQQEVE

SMC2

806

O95347
VMAAEVAKNKESVNK

SMC2

856

O95347
IAQRKTQKKTFMKDS

ZNF644

561

Q9H582
NVKQELAKNKEMKES

TIMM44

66

O43615
VETKATQNFKVMAAK

TTC7A

271

Q9ULT0
KKQEKMTKFQEAVTF

ZNF227

11

Q86WZ6
MEQQRSQLSKKEKKA

PNISR

256

Q8TF01
QQVMKESKEKLTKTK

ZFC3H1

391

O60293
MVTKQVTDAESKLKK

ZFC3H1

821

O60293
TEKFMAKQRKEKEQN

ZNF638

1956

Q14966
KVKVQKKADMVNEDL

UGGT1

1206

Q9NYU2
KKKAAVIIMAVEKQT

UBR5

861

O95071
KAAKVQKLSKNEVLM

EIF2S3

391

P41091