Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionNADH oxidase H202-forming activity

DUOX1 DUOX2

6.91e-062532GO:0106293
GeneOntologyMolecularFunctionNADPH oxidase H202-forming activity

DUOX1 DUOX2

6.88e-055532GO:0106294
GeneOntologyMolecularFunctionglyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity

ALDH2 ALDH1B1

2.46e-049532GO:0043878
GeneOntologyMolecularFunctionNAD(P)H oxidase H2O2-forming activity

DUOX1 DUOX2

4.49e-0412532GO:0016174
GeneOntologyMolecularFunctionsuperoxide-generating NAD(P)H oxidase activity

DUOX1 DUOX2

4.49e-0412532GO:0016175
GeneOntologyMolecularFunctionaldehyde dehydrogenase (NAD+) activity

ALDH2 ALDH1B1

7.10e-0415532GO:0004029
GeneOntologyMolecularFunctionaldehyde dehydrogenase [NAD(P)+] activity

ALDH2 ALDH1B1

9.16e-0417532GO:0004030
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPRG PTPRZ1

9.16e-0417532GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPRG PTPRZ1

9.16e-0417532GO:0019198
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, oxygen as acceptor

DUOX1 DUOX2

1.27e-0320532GO:0050664
GeneOntologyMolecularFunctioncalcium ion binding

SNED1 DUOX1 SCUBE1 HMCN1 DUOX2 ZZEF1 SVEP1

3.49e-03749537GO:0005509
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-19 ERVK-21

4.34e-0337532GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-19 ERVK-21

4.57e-0338532GO:0070001
GeneOntologyBiologicalProcesscuticle development

DUOX1 DUOX2

2.01e-053542GO:0042335
GeneOntologyCellularComponentextracellular matrix

SNED1 ANGPTL6 ADAMTSL1 HMCN1 PTPRZ1 PAPLN LRRN2 PCOLCE2 SVEP1

4.20e-05656549GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

SNED1 ANGPTL6 ADAMTSL1 HMCN1 PTPRZ1 PAPLN LRRN2 PCOLCE2 SVEP1

4.30e-05658549GO:0030312
DomainIg_I-set

ADAMTSL1 HMCN1 ROR2 IGDCC3 ROBO1 PAPLN LRRN2 IGDCC4

4.34e-08190518IPR013098
DomainI-set

ADAMTSL1 HMCN1 ROR2 IGDCC3 ROBO1 PAPLN LRRN2 IGDCC4

4.34e-08190518PF07679
Domain-

SNED1 ADAMTSL1 HMCN1 PTPRG PTPRZ1 ROR2 GPCPD1 IGDCC3 ROBO1 PAPLN LRRN2 IGDCC4

1.62e-0766351122.60.40.10
DomainIGc2

ADAMTSL1 HMCN1 ROR2 IGDCC3 ROBO1 PAPLN LRRN2 IGDCC4

2.23e-07235518SM00408
DomainIg_sub2

ADAMTSL1 HMCN1 ROR2 IGDCC3 ROBO1 PAPLN LRRN2 IGDCC4

2.23e-07235518IPR003598
DomainIg-like_fold

SNED1 ADAMTSL1 HMCN1 PTPRG PTPRZ1 ROR2 GPCPD1 IGDCC3 ROBO1 PAPLN LRRN2 IGDCC4

3.18e-077065112IPR013783
Domainfn3

SNED1 PTPRG PTPRZ1 IGDCC3 ROBO1 IGDCC4

5.06e-06162516PF00041
DomainDUOX1

DUOX1 DUOX2

7.31e-062512IPR029595
DomainFN3

SNED1 PTPRG PTPRZ1 IGDCC3 ROBO1 IGDCC4

1.08e-05185516SM00060
DomainFN3

SNED1 PTPRG PTPRZ1 IGDCC3 ROBO1 IGDCC4

1.64e-05199516PS50853
DomainIG

ADAMTSL1 HMCN1 ROR2 IGDCC3 ROBO1 PAPLN LRRN2 IGDCC4

1.70e-05421518SM00409
DomainIg_sub

ADAMTSL1 HMCN1 ROR2 IGDCC3 ROBO1 PAPLN LRRN2 IGDCC4

1.70e-05421518IPR003599
DomainFN3_dom

SNED1 PTPRG PTPRZ1 IGDCC3 ROBO1 IGDCC4

2.16e-05209516IPR003961
DomainIG_LIKE

ADAMTSL1 HMCN1 ROR2 IGDCC3 ROBO1 PAPLN LRRN2 IGDCC4

5.08e-05491518PS50835
DomainIg-like_dom

ADAMTSL1 HMCN1 ROR2 IGDCC3 ROBO1 PAPLN LRRN2 IGDCC4

6.02e-05503518IPR007110
DomainEGF_Ca-bd_CS

SNED1 SCUBE1 HMCN1 SVEP1

1.42e-0497514IPR018097
DomainNAD_binding_6

DUOX1 DUOX2

1.52e-047512PF08030
DomainFAD_binding_8

DUOX1 DUOX2

1.52e-047512PF08022
DomainFAD-bd_8

DUOX1 DUOX2

1.52e-047512IPR013112
DomainFe_red_NAD-bd_6

DUOX1 DUOX2

1.52e-047512IPR013121
DomainEGF_CA

SNED1 SCUBE1 HMCN1 SVEP1

1.53e-0499514PS01187
DomainASX_HYDROXYL

SNED1 SCUBE1 HMCN1 SVEP1

1.59e-04100514PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

SNED1 SCUBE1 HMCN1 SVEP1

1.99e-04106514IPR000152
DomainHaem_peroxidase

DUOX1 DUOX2

3.24e-0410512IPR010255
DomainAn_peroxidase

DUOX1 DUOX2

3.24e-0410512PF03098
DomainPEROXIDASE_3

DUOX1 DUOX2

3.24e-0410512PS50292
DomainHaem_peroxidase_animal

DUOX1 DUOX2

3.24e-0410512IPR019791
Domain-

DUOX1 DUOX2

3.24e-04105121.10.640.10
DomainEGF_CA

SNED1 SCUBE1 HMCN1 SVEP1

3.42e-04122514SM00179
DomainEGF-like_Ca-bd_dom

SNED1 SCUBE1 HMCN1 SVEP1

3.63e-04124514IPR001881
Domain-

SCUBE1 PCOLCE2 ZZEF1

3.86e-04525132.60.120.290
Domain-

HMCN1 SVEP1

3.96e-04115122.40.155.10
DomainGFP-like

HMCN1 SVEP1

3.96e-0411512IPR023413
DomainEphrin_rec_like

SCUBE1 SVEP1

3.96e-0411512PF07699
DomainCCP

SNED1 CR1 SVEP1

4.31e-0454513SM00032
DomainFerric_reduct

DUOX1 DUOX2

4.74e-0412512PF01794
DomainFe3_Rdtase_TM_dom

DUOX1 DUOX2

4.74e-0412512IPR013130
DomainSUSHI

SNED1 CR1 SVEP1

4.80e-0456513PS50923
DomainSushi_SCR_CCP_dom

SNED1 CR1 SVEP1

5.06e-0457513IPR000436
DomainCUB_dom

SCUBE1 PCOLCE2 ZZEF1

5.06e-0457513IPR000859
DomainPLAC

ADAMTSL1 PAPLN

6.51e-0414512PF08686
DomainTSP_1

ADAMTSL1 HMCN1 PAPLN

6.79e-0463513PF00090
DomainTSP1

ADAMTSL1 HMCN1 PAPLN

7.44e-0465513SM00209
DomainTSP1_rpt

ADAMTSL1 HMCN1 PAPLN

7.44e-0465513IPR000884
DomainTSP1

ADAMTSL1 HMCN1 PAPLN

7.44e-0465513PS50092
DomainAld_DH_CS_GLU

ALDH2 ALDH1B1

8.56e-0416512IPR029510
DomainALPHA_CA_2

PTPRG PTPRZ1

9.68e-0417512PS51144
DomainAld_DH_CS_CYS

ALDH2 ALDH1B1

9.68e-0417512IPR016160
DomainCarb_anhydrase

PTPRG PTPRZ1

9.68e-0417512PF00194
DomainCarb_anhydrase

PTPRG PTPRZ1

9.68e-0417512SM01057
Domain-

PTPRG PTPRZ1

9.68e-04175123.10.200.10
DomainCarbonic_anhydrase_a

PTPRG PTPRZ1

9.68e-0417512IPR001148
DomainALDEHYDE_DEHYDR_GLU

ALDH2 ALDH1B1

1.09e-0318512PS00687
DomainALDEHYDE_DEHYDR_CYS

ALDH2 ALDH1B1

1.09e-0318512PS00070
DomainIGv

HMCN1 ROBO1 PAPLN

1.13e-0375513SM00406
DomainFd_Rdtase_FAD-bd

DUOX1 DUOX2

1.21e-0319512IPR017927
DomainPLAC

ADAMTSL1 PAPLN

1.21e-0319512PS50900
DomainFAD_FR

DUOX1 DUOX2

1.21e-0319512PS51384
DomainAld_DH_C

ALDH2 ALDH1B1

1.21e-0319512IPR016163
DomainAld_DH_N

ALDH2 ALDH1B1

1.21e-0319512IPR016162
DomainAld_DH/histidinol_DH

ALDH2 ALDH1B1

1.21e-0319512IPR016161
Domain-

ALDH2 ALDH1B1

1.21e-03195123.40.605.10
DomainAldedh

ALDH2 ALDH1B1

1.21e-0319512PF00171
DomainPLAC

ADAMTSL1 PAPLN

1.21e-0319512IPR010909
DomainAldehyde_DH_dom

ALDH2 ALDH1B1

1.21e-0319512IPR015590
Domain-

ALDH2 ALDH1B1

1.21e-03195123.40.309.10
DomainRiboflavin_synthase-like_b-brl

DUOX1 DUOX2

1.21e-0319512IPR017938
DomainEGF_CA

SCUBE1 HMCN1 SVEP1

1.67e-0386513PF07645
DomainPeptidase_M12B_ADAM-TS

ADAMTSL1 PAPLN

1.94e-0324512IPR013273
DomainEphrin_rec_like

SCUBE1 SVEP1

2.11e-0325512SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

SCUBE1 SVEP1

2.11e-0325512IPR011641
DomaincEGF

SCUBE1 HMCN1

2.28e-0326512IPR026823
DomaincEGF

SCUBE1 HMCN1

2.28e-0326512PF12662
DomainhEGF

SNED1 SVEP1

2.64e-0328512PF12661
PathwayREACTOME_THYROXINE_BIOSYNTHESIS

DUOX1 DUOX2

2.39e-049372MM14833
PathwayREACTOME_THYROXINE_BIOSYNTHESIS

DUOX1 DUOX2

2.98e-0410372M27120
PathwayKEGG_LIMONENE_AND_PINENE_DEGRADATION

ALDH2 ALDH1B1

2.98e-0410372M17395
PathwayREACTOME_ETHANOL_OXIDATION

ALDH2 ALDH1B1

3.63e-0411372MM15405
PathwayREACTOME_ETHANOL_OXIDATION

ALDH2 ALDH1B1

4.35e-0412372M14663
Pubmed

Digenic DUOX1 and DUOX2 Mutations in Cases With Congenital Hypothyroidism.

DUOX1 DUOX2

2.37e-06254228633507
Pubmed

Genomic structure and chromosomal localization of the mouse gene Punc.

IGDCC3 IGDCC4

2.37e-0625429922388
Pubmed

Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity.

DUOX1 DUOX2

2.37e-06254215972824
Pubmed

Congenital Hypothyroidism due to Oligogenic Mutations in Two Sudanese Families.

DUOX1 DUOX2

2.37e-06254230375286
Pubmed

Comparative genomics, molecular evolution and computational modeling of ALDH1B1 and ALDH2.

ALDH2 ALDH1B1

2.37e-06254223247008
Pubmed

The extracellular A-loop of dual oxidases affects the specificity of reactive oxygen species release.

DUOX1 DUOX2

2.37e-06254225586178
Pubmed

Conserved cysteine residues provide a protein-protein interaction surface in dual oxidase (DUOX) proteins.

DUOX1 DUOX2

2.37e-06254223362256
Pubmed

Activation of dual oxidases Duox1 and Duox2: differential regulation mediated by camp-dependent protein kinase and protein kinase C-dependent phosphorylation.

DUOX1 DUOX2

2.37e-06254219144650
Pubmed

Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.

DUOX1 DUOX2

2.37e-06254210806195
Pubmed

Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox.

DUOX1 DUOX2

2.37e-06254211514595
Pubmed

Synergistic association between two alcohol metabolism relevant genes and coronary artery disease among Chinese hypertensive patients.

ALDH2 ALDH1B1

2.37e-06254225047496
Pubmed

Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium.

DUOX1 DUOX2

2.37e-06254216111680
Pubmed

Role of aldehyde dehydrogenases, alcohol dehydrogenase 1B genotype, alcohol consumption, and their combination in breast cancer in East-Asian women.

ALDH2 ALDH1B1

2.37e-06254232300124
Pubmed

Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling.

DUOX1 DUOX2

2.37e-06254224161126
Pubmed

Reactive oxygen species regulate the levels of dual oxidase (Duox1-2) in human neuroblastoma cells.

DUOX1 DUOX2

2.37e-06254222523549
Pubmed

Expression of nicotinamide adenine dinucleotide phosphate oxidase flavoprotein DUOX genes and proteins in human papillary and follicular thyroid carcinomas.

DUOX1 DUOX2

2.37e-06254211762710
Pubmed

Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system.

DUOX1 DUOX2

2.37e-06254211822874
Pubmed

Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases.

DUOX1 DUOX2

2.37e-06254211753072
Pubmed

Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis.

DUOX1 DUOX2

2.37e-06254223281318
Pubmed

Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer.

DUOX1 DUOX2

2.37e-06254218281478
Pubmed

Structural and functional characterization of the two human ThOX/Duox genes and their 5'-flanking regions.

DUOX1 DUOX2

2.37e-06254215062544
Pubmed

Dual oxidase 1 and NADPH oxidase 2 exert favorable effects in cervical cancer patients by activating immune response.

DUOX1 DUOX2

2.37e-06254231706280
Pubmed

Regulated hydrogen peroxide production by Duox in human airway epithelial cells.

DUOX1 DUOX2

2.37e-06254215677770
Pubmed

Expression of reduced nicotinamide adenine dinucleotide phosphate oxidase (ThoX, LNOX, Duox) genes and proteins in human thyroid tissues.

DUOX1 DUOX2

2.37e-06254211443211
Pubmed

Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cdnas.

DUOX1 DUOX2

2.37e-06254210601291
Pubmed

Dual oxidase 1 and 2 expression in airway epithelium of smokers and patients with mild/moderate chronic obstructive pulmonary disease.

DUOX1 DUOX2

2.37e-06254218177232
Pubmed

Telomere shortening in the esophagus of Japanese alcoholics: relationships with chromoendoscopic findings, ALDH2 and ADH1B genotypes and smoking history.

ALDH2 ALDH1B1

2.37e-06254223667679
Pubmed

Mucosal reactive oxygen species are required for antiviral response: role of Duox in influenza a virus infection.

DUOX1 DUOX2

2.37e-06254224128054
Pubmed

Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense.

DUOX1 DUOX2

2.37e-06254212824283
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

HMCN1 ROR2 IGDCC3 LRRN2 IGDCC4

5.42e-0616254525826454
Pubmed

The association of ADH and ALDH gene variants with alcohol drinking habits and cardiovascular disease risk factors.

ALDH2 ALDH1B1

7.09e-06354218782342
Pubmed

NADPH oxidase DUOX1 and DUOX2 but not NOX4 are independent predictors in hepatocellular carcinoma after hepatectomy.

DUOX1 DUOX2

7.09e-06354221915726
Pubmed

Molecular genetics of human aldehyde dehydrogenase.

ALDH2 ALDH1B1

7.09e-0635421306115
Pubmed

Contribution of the alcohol dehydrogenase-1B genotype and oral microorganisms to high salivary acetaldehyde concentrations in Japanese alcoholic men.

ALDH2 ALDH1B1

7.09e-06354217471563
Pubmed

NADPH oxidase-dependent acid production in airway epithelial cells.

DUOX1 DUOX2

7.09e-06354215210697
Pubmed

Protein tyrosine phosphatase zeta/RPTPbeta interacts with PSD-95/SAP90 family.

PTPRG PTPRZ1

7.09e-06354210521598
Pubmed

Novel RPTPĪ³ and RPTPĪ¶ splice variants from mixed neuron-astrocyte hippocampal cultures as well as from the hippocampi of newborn and adult mice.

PTPRG PTPRZ1

7.09e-06354238952869
Pubmed

Role of nicotinamide adenine dinucleotide phosphate oxidase in mediating vesicant-induced interleukin-6 secretion in human airway epithelial cells.

DUOX1 DUOX2

7.09e-06354224164541
Pubmed

Lipogenic signalling modulates prostate cancer cell adhesion and migration via modification of Rho GTPases.

FASN RHOU

7.09e-06354232139877
Pubmed

Crystal structure of eta-crystallin: adaptation of a class 1 aldehyde dehydrogenase for a new role in the eye lens.

ALDH2 ALDH1B1

7.09e-06354212693930
Pubmed

Mitochondrial NAD dependent aldehyde dehydrogenase either from yeast or human replaces yeast cytoplasmic NADP dependent aldehyde dehydrogenase for the aerobic growth of yeast on ethanol.

ALDH2 ALDH1B1

7.09e-06354223454351
Pubmed

DUOX enzyme activity promotes AKT signalling in prostate cancer cells.

DUOX1 DUOX2

7.09e-06354223225414
Pubmed

Association of duoxes with thyroid peroxidase and its regulation in thyrocytes.

DUOX1 DUOX2

7.09e-06354219952225
Pubmed

MiR-486-3p was downregulated at microRNA profiling of adrenals of multiple endocrine neoplasia type 1 mice, and inhibited human adrenocortical carcinoma cell lines.

FASN MEN1

1.42e-05454234285285
Pubmed

Genetic determinants of both ethanol and acetaldehyde metabolism influence alcohol hypersensitivity and drinking behaviour among Scandinavians.

ALDH2 ALDH1B1

1.42e-05454220205700
Pubmed

Cloning and expression of nope, a new mouse gene of the immunoglobulin superfamily related to guidance receptors.

IGDCC3 IGDCC4

1.42e-05454210708514
Pubmed

Nox4 and Duox1/2 Mediate Redox Activation of Mesenchymal Cell Migration by PDGF.

DUOX1 DUOX2

1.42e-05454227110716
Pubmed

The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules.

PTPRG PTPRZ1

1.42e-05454220133774
Pubmed

The type of DUOX-dependent ROS production is dictated by defined sequences in DUOXA.

DUOX1 DUOX2

1.42e-05454222814254
Pubmed

Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells.

DUOX1 DUOX2

1.42e-05454219339556
Pubmed

Expression of TPO and ThOXs in human thyrocytes is downregulated by IL-1alpha/IFN-gamma, an effect partially mediated by nitric oxide.

DUOX1 DUOX2

2.36e-05554216478776
Pubmed

Complement modulation in the retinal pigment epithelium rescues photoreceptor degeneration in a mouse model of Stargardt disease.

ABCA4 CR1

2.36e-05554228348233
Pubmed

The association of alcohol and alcohol metabolizing gene variants with diabetes and coronary heart disease risk factors in a white population.

ALDH2 ALDH1B1

2.36e-05554220700531
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-19 ERVK-21

2.36e-05554212629516
Pubmed

Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation.

DUOX1 DUOX2

2.36e-05554234784249
Pubmed

Identification of a novel partner of duox: EFP1, a thioredoxin-related protein.

DUOX1 DUOX2

2.36e-05554215561711
Pubmed

Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain.

PTPRG PTPRZ1

2.36e-0555422169617
Pubmed

Structural diversity and evolution of human receptor-like protein tyrosine phosphatases.

PTPRG PTPRZ1

3.54e-0565422170109
Pubmed

Gatm, a creatine synthesis enzyme, is imprinted in mouse placenta.

DUOX1 DUOX2

3.54e-05654212671064
Pubmed

Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult.

DUOX1 DUOX2

3.54e-05654217332529
Pubmed

APX-115, a first-in-class pan-NADPH oxidase (Nox) inhibitor, protects db/db mice from renal injury.

DUOX1 DUOX2

3.54e-05654228165467
Pubmed

BBS mutations modify phenotypic expression of CEP290-related ciliopathies.

ABCA4 BBS7

4.94e-05754223943788
Pubmed

Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase.

DUOX1 DUOX2

4.94e-05754219005069
Pubmed

Maternal aldehyde elimination during pregnancy preserves the fetal genome.

ALDH2 ALDH1B1

4.94e-05754225155611
Pubmed

Genetic polymorphisms and susceptibility to lung disease.

DUOX1 DUOX2

1.06e-041054216608528
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-19 ERVK-21

1.06e-041054212970426
Pubmed

Mitochondrial reactive oxygen species enable proinflammatory signaling through disulfide linkage of NEMO.

DUOX1 DUOX2

1.29e-041154230755476
Pubmed

ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools.

ALDH2 ALDH1B1

1.29e-041154223142317
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

ADAMTSL1 HMCN1 PAPLN PCOLCE2

1.34e-0416754422159717
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-19 ERVK-21

1.55e-041254214557543
Pubmed

A Pellino-2 variant is associated with constitutive NLRP3 inflammasome activation in a family with ocular pterygium-digital keloid dysplasia.

ROBO1 NDUFAF6

2.13e-041454236776133
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTSL1 HMCN1 PAPLN

2.21e-047554320637190
Pubmed

Identification and initial characterization of 5000 expressed sequenced tags (ESTs) each from adult human normal and osteoarthritic cartilage cDNA libraries.

SCUBE1 PCOLCE2

2.45e-041554211597177
Pubmed

Genome-wide association study of recurrent early-onset major depressive disorder.

PTPRG PCARE

2.80e-041654220125088
Pubmed

Receptor protein tyrosine phosphatases are expressed by cycling retinal progenitor cells and involved in neuronal development of mouse retina.

PTPRG PTPRZ1

2.80e-041654218308476
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FASN KIF26A NICN1 PAPLN LARS2 ZZEF1 SH2B2 WNK2

2.88e-04110554835748872
Pubmed

GATA-like protein-1 (GLP-1) is required for normal germ cell development during embryonic oogenesis.

REC8 ZGLP1

3.56e-041854221123517
Pubmed

Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems.

ALDH2 ALDH1B1

5.86e-042354218971422
Pubmed

Centrosome anchoring regulates progenitor properties and cortical formation.

PTPRZ1 ODF2

6.94e-042554232238932
Pubmed

Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice.

DUOX1 DUOX2

7.51e-042654233905568
Pubmed

Molecular profiling of the vestibular lamina highlights a key role for Hedgehog signalling.

SNED1 SCUBE1

1.07e-033154236971701
Pubmed

Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction.

KIF26A ROBO1

1.07e-033154222282597
Pubmed

Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate.

ROR2 ROBO1

1.21e-033354218480165
Pubmed

HSP90 Shapes the Consequences of Human Genetic Variation.

REC8 MEN1

1.44e-033654228215707
Pubmed

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.

NDUFAF6 CR1

1.52e-033754224162737
Cytoband3p21.31

NICN1 INKA1 TMEM89

2.17e-041005333p21.31
Cytoband15q15.3

DUOX1 DUOX2

3.86e-042553215q15.3
CytobandEnsembl 112 genes in cytogenetic band chr3p21

NICN1 LARS2 INKA1 TMEM89

4.94e-04316534chr3p21
CytobandEnsembl 112 genes in cytogenetic band chr9q22

ROR2 ERCC6L2 WNK2

1.63e-03200533chr9q22
Cytoband2q37.3

SNED1 ESPNL

3.62e-03775322q37.3
CytobandEnsembl 112 genes in cytogenetic band chr1q32

ADORA1 LRRN2 CR1

4.63e-03290533chr1q32
Cytoband1q32.1

ADORA1 LRRN2

6.99e-031085321q32.1
CytobandEnsembl 112 genes in cytogenetic band chr15q22

IGDCC3 IGDCC4

1.03e-02132532chr15q22
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

ADAMTSL1 HMCN1 ROR2 IGDCC3 ROBO1 PAPLN LRRN2 IGDCC4

1.03e-09161378593
GeneFamilyFibronectin type III domain containing

SNED1 PTPRG PTPRZ1 IGDCC3 ROBO1 IGDCC4

8.10e-07160376555
GeneFamilyADAMTS like

ADAMTSL1 PAPLN

8.50e-057372947
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SNED1 CR1 SVEP1

2.14e-04573731179
GeneFamilyAldehyde dehydrogenases

ALDH2 ALDH1B1

6.82e-0419372398
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRG PTPRZ1

8.35e-0421372813
GeneFamilyEF-hand domain containing

DUOX1 DUOX2 ZZEF1

1.01e-02219373863
CoexpressionNABA_MATRISOME_PRIMARY_METASTATIC_COLORECTAL_TUMOR

ADAMTSL1 HMCN1 PAPLN SVEP1

5.78e-0659524M47989
CoexpressionNABA_ECM_GLYCOPROTEINS

SNED1 HMCN1 PAPLN PCOLCE2 SVEP1

3.84e-05191525MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

SNED1 HMCN1 PAPLN PCOLCE2 SVEP1

4.34e-05196525M3008
CoexpressionGSE360_L_DONOVANI_VS_T_GONDII_MAC_DN

SNED1 FASN RAB33A ACD MEN1

4.78e-05200525M5234
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2

SNED1 FASN SCUBE1 ADAMTSL1 ABCA4 HMCN1 NICN1 GPCPD1 ALDH2 LARS2 SVEP1 IGDCC4

2.57e-0512285112facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2
CoexpressionAtlasECTO UCB CD34+Z_vs_ECTO blastocyst-Confounder_removed-fold2.0_adjp0.05

SCUBE1 KIF26A PTPRZ1 PAPLN PCOLCE2 ALDH2

8.28e-05302516PCBC_ratio_ECTO UCB CD34+Z_vs_ECTO blastocyst_cfr-2X-p05
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

SCUBE1 ADAMTSL1 HMCN1 ROBO1 ALDH1B1 RHOU SVEP1 INKA1 IGDCC4

8.60e-05777519gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

HMCN1 PTPRG ROR2 ROBO1 LRRN2 SVEP1

8.26e-08187526e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

SNED1 HMCN1 PTPRG ROR2 ROBO1 SVEP1

9.96e-08193526acad568621ed677031797b8c2e34dafea798d681
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

SNED1 HMCN1 PTPRG ROR2 ROBO1 SVEP1

1.06e-07195526603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

SNED1 HMCN1 PTPRG ROR2 ROBO1 SVEP1

1.12e-07197526f1c8936986123a3151140c374fcd62d6705c530b
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

SNED1 HMCN1 PTPRG ROR2 ROBO1 SVEP1

1.12e-07197526fb847f2277609c31fffcdf49517243ce0684facf
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

SNED1 HMCN1 PTPRG ROR2 ROBO1 SVEP1

1.16e-07198526df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

SNED1 HMCN1 PTPRG ROR2 ROBO1 SVEP1

1.19e-071995264bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SNED1 SCUBE1 PTPRG NICN1 PAPLN SVEP1

1.19e-071995263835452e4848d7f7dd8651c17b746b271ef39688
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SNED1 SCUBE1 PTPRG NICN1 PAPLN SVEP1

1.19e-071995269c2db0bb94cba71a3cc1827844da090e213e0258
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZGLP1 PCOLCE2 WNK2 TFF2 IGDCC4

1.63e-06170525a121e10099faaeb60251eec162f38caf7c4238c2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 ROBO1 PCARE PCOLCE2 CR1

1.73e-061725256c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HMCN1 PTPRG ROR2 ROBO1 PAPLN

1.88e-061755251799a7be623dc3bf53ba580a7c47d2619969d708
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZGLP1 PCOLCE2 WNK2 TFF2 IGDCC4

1.88e-06175525f7cd2ef79d91d64976fcdb5f1e7343b24ba27456
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADORA1 GPCPD1 PCARE PCOLCE2 ALDH2

2.22e-06181525166ff44fcc0a2943b7f485ea8a9c314964e013bb
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

SNED1 ADAMTSL1 ROR2 SVEP1 IGDCC4

2.47e-06185525fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCellCOVID-19-Fibroblasts-Adventitial_FB|COVID-19 / group, cell type (main and fine annotations)

SNED1 ADAMTSL1 PTPRG ROR2 SVEP1

2.47e-06185525a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ROR2 PCOLCE2 SVEP1 IGDCC4

2.54e-0618652594d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs|metastatic_Lymph_Node / Location, Cell class and cell subclass

HMCN1 ROR2 ROBO1 PAPLN SVEP1

2.61e-06187525e04fb35f2f5b120659d06b5ae427ab1ec56d5c36
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

HMCN1 PTPRG ROR2 ROBO1 SVEP1

2.61e-06187525bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SNED1 ADAMTSL1 ROR2 SVEP1 IGDCC4

2.75e-06189525d531399749409d614adca13d181830c6e3287508
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ROR2 ROBO1 PAPLN SVEP1 IGDCC4

2.82e-0619052545df8fee00f8949937863159d7aa042e72748d9b
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

HMCN1 PTPRG ROR2 ROBO1 SVEP1

2.82e-061905253a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SNED1 ROR2 ROBO1 SVEP1 IGDCC4

2.89e-06191525b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

SNED1 PTPRG ROBO1 PCOLCE2 SVEP1

2.89e-06191525d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HMCN1 PTPRG ROR2 ROBO1 SVEP1

2.89e-061915256688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ROR2 ROBO1 PAPLN SVEP1 IGDCC4

2.97e-06192525df1545670370fb1010c567cd059c2783eab315f7
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HMCN1 PTPRG ROR2 ROBO1 SVEP1

2.97e-0619252599ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

SNED1 ADAMTSL1 ROR2 SVEP1 IGDCC4

2.97e-06192525d21f0f577156f17c899b08871046a26b88aea011
ToppCellFibroblasts-CD55+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SNED1 ADAMTSL1 PTPRG PAPLN PCOLCE2

3.04e-061935258f4bf9a2fbedae35432dad96730b00c70185874c
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

HMCN1 PTPRG ROR2 ROBO1 SVEP1

3.04e-0619352599525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

SNED1 HMCN1 PTPRG ROR2 ROBO1

3.04e-06193525e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-FDC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HMCN1 ROBO1 PAPLN PCOLCE2 CR1

3.12e-06194525f9fbb043411546d8c9e0321a64165d411f44aeb7
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SNED1 HMCN1 PTPRG ROR2 SVEP1

3.12e-06194525011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SNED1 ROR2 ROBO1 SVEP1 IGDCC4

3.12e-0619452560622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SNED1 ROR2 ROBO1 SVEP1 IGDCC4

3.12e-0619452589b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SNED1 ADAMTSL1 PTPRG ROR2 SVEP1

3.20e-06195525ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 PCOLCE2 ALDH2 RHOU SVEP1

3.20e-06195525598b69032a8441a23749b27863d80f7a1fc82a96
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HMCN1 ROBO1 PAPLN PCOLCE2 CR1

3.20e-061955251be9502577267ca2a04656a99d57e3e2f124d92e
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

SNED1 PTPRG ROBO1 PCOLCE2 SVEP1

3.20e-061955256a02ebbeb3199447ddce64d92d8809436e040eba
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 PCOLCE2 ALDH2 RHOU SVEP1

3.20e-061955258aa753934debffe5ae4b5eecb6b50c46d17cc3ec
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HMCN1 PTPRG ROR2 ROBO1 SVEP1

3.28e-061965257d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SNED1 PTPRG ROR2 ROBO1 SVEP1

3.36e-0619752573a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 ADAMTSL1 ROR2 ROBO1 SVEP1

3.36e-061975259b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

SNED1 HMCN1 ROR2 ROBO1 SVEP1

3.45e-061985253ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCUBE1 HMCN1 ROR2 ROBO1 SVEP1

3.45e-06198525300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 ADAMTSL1 ROR2 ROBO1 SVEP1

3.45e-06198525a860246bcea847249a78fd2e86ed8e04371060db
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HMCN1 PTPRG ROR2 ROBO1 SVEP1

3.45e-061985258f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

ANGPTL6 ADAMTSL1 HMCN1 ROR2 SVEP1

3.45e-06198525bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCellFetal_29-31_weeks-Mesenchymal|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SNED1 HMCN1 PTPRG ROR2 SVEP1

3.45e-0619852521cf4d81386761d09d0f6829c01c198e5524176d
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SNED1 SCUBE1 ADAMTSL1 PAPLN LRRN2

3.53e-06199525fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCellE16.5-Mesenchymal-Mesenchymal_structural|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 PCOLCE2 ALDH2 RHOU SVEP1

3.53e-061995252cec0e370ee9bb3c88a7acb5519e9ea8ddb399bc
ToppCellPSB-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HMCN1 PTPRG PTPRZ1 ALDH2 INKA1

3.53e-061995252add64c3e4cb6384ec381f34c3f1f77e13e3f27c
ToppCellPCW_10-12-Mesenchymal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SNED1 PTPRG ROR2 ROBO1 SVEP1

3.53e-06199525a09292de4c4447b8eee55d401808e43b817321cc
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 PCOLCE2 ALDH2 RHOU SVEP1

3.53e-061995259e87b64e16d595701c3beb07aa835afe3330bd10
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SNED1 ADAMTSL1 PTPRG PCOLCE2 SVEP1

3.62e-062005250c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellControl-Fibroblasts-Mesothelial_FB|Control / group, cell type (main and fine annotations)

ADAMTSL1 ROBO1 PAPLN CR1

2.10e-05139524e769beb031b262dd92c9605b07dbf3c29fb82520
ToppCellControl-NK|World / Disease group and Cell class

DUOX1 ZGLP1 FOLR1 IGDCC4

2.35e-05143524fe08adc9472dfd4242497d6c614d0490713261da
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCUBE1 HMCN1 NICN1 ALDH1B1

3.56e-051595247cda111bb98f1241989e49d490bdf51a712ea589
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 PTPRG PTPRZ1 SVEP1

3.65e-05160524c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 PTPRG PTPRZ1 SVEP1

3.65e-0516052425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Trachea-nan-18m-Epithelial-mucus_secreting_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA1 KIF26A FOLR1 TMEM89

4.12e-051655247e7643834ed483aec04f513cca38d6367fda9ff8
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 PTPRZ1 ROBO1 TMEM89

4.31e-051675242184c2760b6142e62124a2454a552723e20d4f61
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3|TCGA-Stomach / Sample_Type by Project: Shred V9

SNED1 HMCN1 CR1 SVEP1

4.31e-05167524d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCOLCE2 ALDH2 CR1 SH2B2

4.42e-05168524eba865465feb0f42055bb8f98946050eeb03d177
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 ROBO1 PCOLCE2 CR1

4.42e-05168524315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

PAPLN ALDH2 SVEP1 WNK2

4.52e-0516952484b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-stromal_related-FDC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ROBO1 PAPLN PCOLCE2 CR1

4.52e-0516952449a54fb2ea9db5c45e107f304838c536908308bb
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 PCARE PCOLCE2 CR1

4.62e-0517052460bbd738c12e64e483485586c30057304884f5a6
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA1 FOLR1 SH2B2 WNK2

4.62e-05170524c638dfde9ce30190abbe0caea1c3eb874af09857
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 FASN ROR2 SVEP1

4.73e-05171524972fab891135bd755d5526cbc5a963200067b0a6
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANGPTL6 HMCN1 GPATCH2L ZNF248

4.73e-05171524e852d0e8589eecf4a2e5fea039b52a67c5d58dbd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 FASN ROR2 SVEP1

4.73e-051715242a77ed79c6f2e700e789c80451a70ecb31639719
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 PCARE PCOLCE2 CR1

4.84e-05172524381ae1c3c07d0a424f43455ec571653b192a946a
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte-3|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA1 IGDCC3 ROBO1 RHOU

5.06e-0517452476310c0af1d7df6a4de3816838b2ac2892f68746
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 PCARE PCOLCE2 CR1

5.06e-05174524dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN1 PTPRZ1 ROR2 SVEP1

5.29e-051765249bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN1 PTPRZ1 ROR2 SVEP1

5.29e-051765243f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCelldroplet-Limb_Muscle-nan-21m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR1 ROR2 WNK2 INKA1

5.41e-05177524291231b1520c135e92739e201495fe1935efa927
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF26A ZNF273 ALDH2 TFF2

5.41e-051775246248c0dcad302de61a66163ee84b3b79096150d7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 PCARE PCOLCE2 CR1

5.65e-051795247394e77e665bf16d3733df91bb12907be460ab44
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

SNED1 PTPRG ROBO1 PCOLCE2

5.65e-05179524dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SNED1 ROR2 SVEP1 IGDCC4

5.77e-0518052408ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA1 FOLR1 RHOU WNK2

5.77e-05180524d67d3196e6cc3dcd31023a4dc69310226181d583
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SCUBE1 PTPRG ROR2 ROBO1

5.77e-0518052401f2e5d96016823482f89ba503d007d4bd88eeac
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA1 FOLR1 RHOU WNK2

5.77e-05180524573308d43425d9fba20787abdb7f8efefc48efb5
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 PCARE PCOLCE2 CR1

5.90e-051815245bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 PCARE PCOLCE2 CR1

5.90e-051815248e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PTPRZ1 FOLR1 PCOLCE2 IGDCC4

6.03e-05182524ba066ff9029cc052b76e2330ec168cb2e9b7e498
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

HMCN1 FOLR1 PCOLCE2 ALDH2

6.03e-05182524a035d45fd512bee8dac38eb387dbf39f5a8a1fed
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA1 ADAMTSL1 PTPRZ1 ROR2

6.16e-051835240e8fb371d8eac777451c76f41d53577f5dfb740d
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PTPRZ1 FOLR1 ROR2 PCOLCE2

6.16e-0518352427a57cd8ea924420e182f3d72f5b29b00dea8fa0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 ROBO1 PCOLCE2 CR1

6.16e-05183524848fc6dd129150897ee339343e83c645b6e779eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 ROBO1 PCOLCE2 CR1

6.16e-051835247c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA1 ADAMTSL1 PTPRZ1 ROR2

6.16e-05183524cbc3b00faa7e4e0dbbbc8ee105467c65241c7470
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

HMCN1 PTPRG ROBO1 SVEP1

6.29e-0518452467164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 ROBO1 PCOLCE2 SVEP1

6.29e-051845243bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCelldroplet-Kidney-nan-21m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 ROBO1 PCOLCE2 SVEP1

6.42e-0518552433cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 KIF26A PTPRZ1 IGDCC3

6.42e-05185524f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SNED1 ROBO1 PCOLCE2 SVEP1

6.42e-051855248f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 ROBO1 PCOLCE2 SVEP1

6.42e-051855249954fc85b183c1cc45c3c24e3dadc7984ee6f649
ComputationalMetal ion (zinc) binding.

FASN PTPRG PTPRZ1

3.75e-0445343MODULE_280
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

FOLR1 DUOX2 TFF2

5.12e-0450343GAVISH_3CA_METAPROGRAM_EPITHELIAL_PDAC_RELATED_1
Diseasephenylketonuria (implicated_via_orthology)

DUOX1 DUOX2

1.75e-054512DOID:9281 (implicated_via_orthology)
DiseaseVentricular Dysfunction

ADORA1 ALDH2

8.15e-058512C0242973
Diseaseprimary bacterial infectious disease (implicated_via_orthology)

DUOX1 DUOX2

1.05e-049512DOID:0050338 (implicated_via_orthology)
Diseasehypothyroidism (implicated_via_orthology)

DUOX1 DUOX2

2.26e-0413512DOID:1459 (implicated_via_orthology)
Diseasecongenital hypothyroidism (implicated_via_orthology)

DUOX1 DUOX2

2.63e-0414512DOID:0050328 (implicated_via_orthology)
DiseaseAge-related macular degeneration

ABCA4 HMCN1

4.40e-0418512cv:C0242383
DiseaseAge related macular degeneration

ABCA4 HMCN1

1.24e-0330512C0242383
Diseasepresubiculum volume

ADAMTSL1 WNK2

1.32e-0331512EFO_0009400

Protein segments in the cluster

PeptideGeneStartEntry
VRHFQCPKWPNPDAP

PTPRG

1311

P23470
HSWVVFCLPEVPEKP

BBS7

521

Q8IWZ6
VWVPGPTDDHCPAKP

ERVK-19

131

O71037
HLCGPGPVRAWKNPE

CXorf49;

161

A8MYA2
EHPGWVPGVCVKNLV

ABCA4

921

P78363
EPGRPPDWFSQKHCA

BRD8

51

Q9H0E9
KIWNDHFRCQPAPPI

ADORA1

301

P30542
TRHEPVGVCGQIIPW

ALDH1B1

171

P30837
LHWCPPTEPNGEIVE

IGDCC4

866

Q8TDY8
WTHCAQPPPKALRRE

REC8

366

O95072
WIQECNGHAVPPLVP

RAB33A

131

Q14088
CKWEEGSPTPVLHVG

MEN1

426

O00255
VFVWHKGDPCPQPRQ

DUOX1

556

Q9NRD9
EVAPGVQPLPFWCSH

ESPNL

581

Q6ZVH7
PRPKSTPDACLEHWQ

INKA1

151

Q96EL1
CQAQGEPPPHVTWLK

IGDCC3

351

Q8IVU1
ATAAVPVVPWHVPCP

LRRN2

16

O75325
QPNVFVWHKGAPCPQ

DUOX2

556

Q9NRD8
KAVPEHLCSWGPRPA

ADAMTSL1

1701

Q8N6G6
CDNPPHQPVAIELWK

NDUFAF6

126

Q330K2
DTHQGTPEPCKAIVW

KIF26A

906

Q9ULI4
PAGVTCVWHIVAPKN

PCOLCE2

176

Q9UKZ9
LEVRHFQCPKWPNPD

PTPRZ1

2181

P23471
CEVTGNPVPEITWHK

HMCN1

2501

Q96RW7
PKTIGGPCQVIVHKW

GPCPD1

76

Q9NPB8
AAHWSTKPPICQRIP

CR1

601

P17927
TAHWSTKPPICQRIP

CR1

1051

P17927
HPAVPTKPVGPWQDC

ANGPTL6

246

Q8NI99
WVHGPIDDRCPAKPE

ERVK-21

131

P61565
TVPNLLPKWAPDHCS

GPATCH2L

261

Q9NWQ4
KDIWHPGERCLAPSP

ERCC6L2

26

Q5T890
SWEECKQRCPPGVVP

FASN

626

P49327
NAECVWHIAPPPKRR

SCUBE1

821

Q8IWY4
KPGPEDKLHEQCRPW

FOLR1

46

P15328
RIKFVPVPCGHQDWS

PCARE

551

A6NGG8
KWENPPHCLEITPPS

ODF2

81

Q5BJF6
RQRYWGTPIPIVHCP

LARS2

451

Q15031
TFPKWLSHPVPCEQP

NICN1

146

Q9BSH3
LHCKVAGNPPPNVRW

ROR2

81

Q01974
ENGTWSHPVPLCKPN

SVEP1

3341

Q4LDE5
IRVCQPHGVWSEPPQ

SNED1

736

Q8TER0
QEPCSVWEPPKRHRD

ACD

396

Q96AP0
TRHEPVGVCGQIIPW

ALDH2

171

P05091
EKWVPEIRCHCPKAP

RHOU

141

Q7L0Q8
KPPVVCSHFAQDLWP

ZNF273

106

Q14593
NLHPCPETKRWKAGP

PAPLN

356

O95428
PWRQPERRHPKGGEC

RNF25

346

Q96BH1
VPWCFHPLPKQESDQ

TFF2

66

Q03403
VPVPVPDWRQFCELH

SH2B2

16

O14492
CQPPRGHPEPTISWK

ROBO1

191

Q9Y6N7
SSPLWKPVFRHQVCP

ZZEF1

1246

O43149
KGEHPQVTTEPCGPW

TMEM89

96

A2RUT3
RWFIICPVAEHPAPE

WNK2

1311

Q9Y3S1
CPRVHKEPAQVGTPW

ZGLP1

11

P0C6A0
PWILEKGFPSQCHPE

ZNF248

66

Q8NDW4
RPHKCSIPWVPGRNH

ZNF683

376

Q8IZ20