Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	nuclear DNA replication	DONSON WRN DACH1 MCM3	1.33e-05	46	65	4	GO:0033260
GeneOntologyBiologicalProcess	cell cycle DNA replication	DONSON WRN DACH1 MCM3	2.01e-05	51	65	4	GO:0044786
GeneOntologyCellularComponent	replication fork	DONSON WRN MCM3 TP53BP1	9.72e-05	77	65	4	GO:0005657
Domain	SH3	SHANK1 PALS1 SORBS2 TRIO MYO7A ARHGEF38 MACF1	9.90e-06	216	65	7	PS50002
Domain	SH3_domain	SHANK1 PALS1 SORBS2 TRIO MYO7A ARHGEF38 MACF1	1.12e-05	220	65	7	IPR001452
Domain	SH3	SHANK1 PALS1 SORBS2 TRIO MYO7A ARHGEF38	1.04e-04	216	65	6	SM00326
Domain	SH3_2	SHANK1 PALS1 SORBS2 ARHGEF38	2.29e-04	86	65	4	IPR011511
Domain	SH3_2	SHANK1 PALS1 SORBS2 ARHGEF38	2.29e-04	86	65	4	PF07653
Domain	DH_1	TRIO ARHGEF38 ARHGEF18	1.38e-03	63	65	3	PS00741
Domain	RhoGEF	TRIO ARHGEF38 ARHGEF18	1.72e-03	68	65	3	SM00325
Domain	RhoGEF	TRIO ARHGEF38 ARHGEF18	1.86e-03	70	65	3	PF00621
Domain	DH_2	TRIO ARHGEF38 ARHGEF18	1.86e-03	70	65	3	PS50010
Domain	DH-domain	TRIO ARHGEF38 ARHGEF18	1.94e-03	71	65	3	IPR000219
Domain	-	TRIO ARHGEF38 ARHGEF18	1.94e-03	71	65	3	1.20.900.10
Domain	-	ACIN1 SF3B2	2.40e-03	21	65	2	1.10.720.30
Domain	SAP	ACIN1 SF3B2	2.63e-03	22	65	2	PF02037
Domain	SAP	ACIN1 SF3B2	2.88e-03	23	65	2	SM00513
Domain	Spectrin	TRIO MACF1	2.88e-03	23	65	2	PF00435
Domain	SAP	ACIN1 SF3B2	3.40e-03	25	65	2	PS50800
Domain	SAP_dom	ACIN1 SF3B2	3.40e-03	25	65	2	IPR003034
Domain	Spectrin_repeat	TRIO MACF1	4.56e-03	29	65	2	IPR002017
Domain	Spectrin/alpha-actinin	TRIO MACF1	5.53e-03	32	65	2	IPR018159
Domain	SPEC	TRIO MACF1	5.53e-03	32	65	2	SM00150
Domain	Znf_C2H2	SORBS2 ZFAT ARID2 ZSCAN9 ZFHX2 ZNF322 ZNF208 ZNF761	6.62e-03	805	65	8	IPR007087
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	ARID2 NAP1L1 ACIN1 MCM3 TAF1 HUWE1 EDC4 SF3B2 TP53BP1 HDLBP	8.41e-10	332	67	10	32786267
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	PALS1 ARID2 NAP1L1 DACH1 ACIN1 MCM3 TAF1 HUWE1 EDC4 TP53BP1 HDLBP	7.94e-09	549	67	11	38280479
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	TRIO MYO7A POLR2E ACIN1 MACF1 TRIM21 TAF1 HUWE1	4.48e-07	358	67	8	32460013
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 PALS1 SORBS2 TRIO ARHGEF18 MACF1 MCM3 TRIM21 HUWE1 EDC4 TP53BP1	2.16e-06	963	67	11	28671696
Pubmed	CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism.	PALS1 TRIM26 PPP1R15B POLR2E OTUB1 NAP1L1	2.57e-06	201	67	6	34917906
Pubmed	Protease Activity Profiling via Programmable Phage Display of Comprehensive Proteome-Scale Peptide Libraries.	CASP1 HUWE1	3.66e-06	2	67	2	33099407
Pubmed	SPP1 overexpression is associated with poor outcomes in ALK fusion lung cancer patients without receiving targeted therapy.	SPP1 ALK	3.66e-06	2	67	2	34234236
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	POLR2E NMRAL1 NAP1L1 RCN1 TRIM21 HUWE1 SF3B2 TP53BP1 TNS3	4.13e-06	647	67	9	26618866
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	PALS1 POLR2E ACIN1 EDC4 SF3B2 HDLBP	4.33e-06	220	67	6	24550385
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NAP1L1 ACIN1 MACF1 MPHOSPH10 HUWE1 EDC4 SF3B2 TP53BP1 HDLBP	4.45e-06	653	67	9	22586326
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	CDK5RAP3 CYB5R3 HLCS MACF1 MCM3 CACHD1 MPHOSPH9 SF3B2 HDLBP	8.51e-06	708	67	9	39231216
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	TRIM26 POLR2E NAP1L1 MPHOSPH10 HUWE1 SF3B2	9.19e-06	251	67	6	28077445
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	SHANK1 RELCH SORBS2 TRIO CYB5R3 MACF1 HUWE1 EDC4 ATP1A2 TP53BP1 HDLBP	1.06e-05	1139	67	11	36417873
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	PHKA2 PALS1 OTUB1 NAP1L1 RCN1 MACF1 MCM3 TRIM21 HUWE1 SF3B2 HDLBP	1.15e-05	1149	67	11	35446349
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ARID2 CYB5R3 NAP1L1 HLCS ACIN1 MACF1 EDC4 SF3B2 TP53BP1 HDLBP	1.15e-05	934	67	10	33916271
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	ARID2 DACH1 ACIN1 MCM3 MPHOSPH10 TAF1 ALK SF3B2 TP53BP1 HDLBP	1.39e-05	954	67	10	36373674
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	ACIN1 MCM3 MPHOSPH10 SF3B2 HDLBP	1.62e-05	163	67	5	22113938
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	SHANK1 SORBS2 TRIO NMRAL1 ARHGEF18 MACF1	1.74e-05	281	67	6	28706196
Pubmed	Proteomic analysis identifies novel binding partners of BAP1.	POLR2E NAP1L1 HUWE1 SF3B2	1.78e-05	80	67	4	34591877
Pubmed	Functional proteomics mapping of a human signaling pathway.	PHKA2 PPP1R15B OTUB1 MACF1 MPHOSPH10 HUWE1 CCDC181 HDLBP	1.79e-05	591	67	8	15231748
Pubmed	A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.	POLR2E OTUB1 CYB5R3 NAP1L1 ACIN1 MCM3 HUWE1 EDC4 HDLBP	1.95e-05	786	67	9	29128334
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	TRIM26 OTUB1 NAP1L1 RCN1 MACF1 TRIM21 SF3B2 HDLBP	2.02e-05	601	67	8	33658012
Pubmed	TRIM26 promotes non-small cell lung cancer survival by inducing PBX1 degradation.	TRIM26 HUWE1	2.19e-05	4	67	2	37324936
Pubmed	Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.	PHKA2 ACIN1 TRIM21 TP53BP1	2.26e-05	85	67	4	16051665
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	POLR2E NAP1L1 RCN1 ACIN1 MACF1 MCM3 HUWE1 EDC4 SF3B2 HDLBP	2.54e-05	1024	67	10	24711643
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	PALS1 TRIM26 POLR2E NAP1L1 ACIN1 MCM3 TRIM21 MPHOSPH10 EDC4 SF3B2 HDLBP	2.64e-05	1257	67	11	36526897
Pubmed	Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event.	ARID2 ACIN1 MCM3 TRIM21 SF3B2	2.76e-05	182	67	5	26527279
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SHANK1 SORBS2 TRIO NAP1L1 HLCS MACF1 CACHD1 TAF1 HUWE1 ATP1A2 SF3B2	3.23e-05	1285	67	11	35914814
Pubmed	Functional specialization of beta-arrestin interactions revealed by proteomic analysis.	PHKA2 POLR2E NAP1L1 MCM3 SF3B2 HDLBP	3.42e-05	317	67	6	17620599
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ORAI1 CDK5RAP3 TRIM26 ACIN1 ARHGEF18 MACF1 MPHOSPH10 HUWE1 ACVR2A TP53BP1	4.11e-05	1084	67	10	11544199
Pubmed	A human MAP kinase interactome.	SHANK1 ARID2 MACF1 TRIM21 MPHOSPH9 TAF1 HDLBP	4.20e-05	486	67	7	20936779
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	DONSON TRIO SPP1 MACF1 HUWE1 TNS3	4.42e-05	332	67	6	37433992
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	STON1 TRIO MACF1 EDC4 TNS3	5.33e-05	209	67	5	36779422
Pubmed	The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3.	CDK5RAP3 CYB5R3	5.46e-05	6	67	2	36543799
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	SHANK1 TRIO MYO7A LRRK2 NAP1L1 MCM3 SF3B2	5.91e-05	513	67	7	25798074
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	CDK5RAP3 ALG5 POLR2E NAP1L1 MCM3 HUWE1 ATP1A2 TP53BP1	6.17e-05	704	67	8	29955894
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	ARID2 OTUB1 ACIN1 MCM3 SF3B2	6.79e-05	220	67	5	35785414
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	SORBS2 ACIN1 MACF1 TRIM21 SF3B2 TP53BP1	6.92e-05	360	67	6	33111431
Pubmed	The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.	CDK5RAP3 ZFAT NAP1L1 HUWE1 HDLBP	7.55e-05	225	67	5	25277244
Pubmed	Defining the membrane proteome of NK cells.	ORAI1 CDK5RAP3 ALG5 CYB5R3 NAP1L1 PAM MCM3 MPHOSPH9 HUWE1 EDC4	7.65e-05	1168	67	10	19946888
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	TRIO RCN1 HLCS ARHGEF18 MPHOSPH9 HUWE1 SF3B2 TNS3	8.17e-05	733	67	8	34672954
Pubmed	The role of Rho-GEF Trio in regulating tooth root development through the p38 MAPK pathway.	TRIO SPP1	1.02e-04	8	67	2	30268758
Pubmed	Fgf8 genetic labeling reveals the early specification of vestibular hair cell type in mouse utricle.	MYO7A SPP1	1.02e-04	8	67	2	33046506
Pubmed	Identification of novel M phase phosphoproteins by expression cloning.	MPHOSPH9 MPHOSPH10	1.02e-04	8	67	2	8885239
Pubmed	Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.	TRIM26 ARID2 POLR2E ARHGEF18 TAF1 SF3B2	1.07e-04	390	67	6	17643375
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	ARID2 POLR2E NAP1L1 TAF1 EDC4 TP53BP1	1.13e-04	394	67	6	27248496
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	OTUB1 NAP1L1 RCN1 ACIN1 MCM3 MPHOSPH10 HUWE1 SF3B2 TP53BP1	1.14e-04	989	67	9	36424410
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	STON1 PPP1R15B LRRK2 WRN CYB5R3 MCM3 MPHOSPH9 HUWE1	1.22e-04	777	67	8	35844135
Pubmed	Werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain.	OTUB1 NAP1L1 HUWE1	1.26e-04	50	67	3	17550899
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ORAI1 CDK5RAP3 TRIM26 ARID2 POLR2E WRN NAP1L1 MACF1 MPHOSPH10 EDC4 HDLBP	1.27e-04	1497	67	11	31527615
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	ACIN1 MACF1 TRIM21 HUWE1 EDC4 SF3B2 HDLBP	1.29e-04	582	67	7	20467437
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	ACIN1 MCM3 TRIM21 TAF1 HUWE1 SF3B2 TP53BP1	1.31e-04	583	67	7	29844126
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	PALS1 POLR2E RCN1 ACIN1 MCM3 MPHOSPH10 HUWE1 SF3B2 TNS3 HDLBP	1.31e-04	1247	67	10	27684187
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	TRIM26 ARID2 MACF1 MCM3 HUWE1 TP53BP1 HDLBP	1.38e-04	588	67	7	38580884
Pubmed	Proteomic analysis of the NOS2 interactome in human airway epithelial cells.	NAP1L1 RCN1 TRIM21 HUWE1	1.50e-04	138	67	4	23438482
Pubmed	HSCARG negatively regulates the cellular antiviral RIG-I like receptor signaling pathway by inhibiting TRAF3 ubiquitination via recruiting OTUB1.	OTUB1 NMRAL1	1.63e-04	10	67	2	24763515
Pubmed	EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.	POLR2E TAF1	1.63e-04	10	67	2	9488465
Pubmed	SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.	CYB5R3 ACIN1 MCM3 HUWE1 EDC4 SF3B2 HDLBP	1.67e-04	607	67	7	39147351
Pubmed	Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.	OTUB1 MACF1 MCM3 HUWE1	1.72e-04	143	67	4	30397336
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RELCH TRIO POLR2E RCN1 CACHD1 MPHOSPH9 HUWE1 TNS3 HDLBP	1.78e-04	1049	67	9	27880917
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	WRN ACIN1 SF3B2 TP53BP1 HDLBP	1.80e-04	271	67	5	32433965
Pubmed	Novel cell types and developmental lineages revealed by single-cell RNA-seq analysis of the mouse crista ampullaris.	MYO7A SPP1 RCN1	1.86e-04	57	67	3	34003106
Pubmed	BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein.	SHANK1 RELCH LRRK2	1.86e-04	57	67	3	27433848
Pubmed	Chromatin accessibility complex subunit 1 enhances tumor growth by regulating the oncogenic transcription of YAP in breast and cervical cancer.	MCM3 HUWE1 SF3B2	1.86e-04	57	67	3	38223760
Pubmed	USP7 controls NGN3 stability and pancreatic endocrine lineage development.	SPP1 MACF1 HUWE1	1.95e-04	58	67	3	37117185
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	ALG5 POLR2E WRN NAP1L1 HLCS ACIN1 MCM3 MPHOSPH10 HUWE1 SF3B2	2.05e-04	1318	67	10	30463901
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	CDK5RAP3 TRIO MACF1 MLLT10	2.12e-04	151	67	4	17043677
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	WRN DACH1 ACIN1 TAF1 SF3B2	2.20e-04	283	67	5	30585729
Pubmed	BMPR-II is dispensable for formation of the limb skeleton.	SPP1 ACVR2A	2.38e-04	12	67	2	21538804
Pubmed	Characterization of spatial and temporal development of Type I and Type II hair cells in the mouse utricle using new cell-type-specific markers.	MYO7A SPP1	2.38e-04	12	67	2	30455179
Pubmed	Retinoic acid degradation shapes zonal development of vestibular organs and sensitivity to transient linear accelerations.	MYO7A SPP1	2.38e-04	12	67	2	31896743
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	RELCH TRIM21 HUWE1 TP53BP1 HDLBP	2.39e-04	288	67	5	23383273
Pubmed	BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62.	MCM3 EDC4 TNS3 HDLBP	2.40e-04	156	67	4	32850835
Pubmed	Direct and indirect control of mitogen-activated protein kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/RAF1 kinase, by the deubiquitylating enzyme USP15.	TRIM26 OTUB1 TRIM21	2.50e-04	63	67	3	23105109
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	POLR2E NAP1L1 ACIN1 MACF1 MCM3 HUWE1 SF3B2 TP53BP1 TNS3 HDLBP	2.53e-04	1353	67	10	29467282
Pubmed	A novel LZAP-binding protein, NLBP, inhibits cell invasion.	CDK5RAP3 HUWE1	2.81e-04	13	67	2	20164180
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	SPP1 NAP1L1 ACIN1 TRIM21 HUWE1 TP53BP1	2.90e-04	469	67	6	27634302
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	OTUB1 ACIN1 MCM3 HUWE1 EDC4 ATP1A2 HDLBP	2.92e-04	665	67	7	30457570
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	TRIO ARID2 MACF1 MPHOSPH10 TP53BP1 TNS3	3.00e-04	472	67	6	38943005
Pubmed	Aberrant cochlear hair cell attachments caused by Nectin-3 deficiency result in hair bundle abnormalities.	PALS1 MYO7A	3.28e-04	14	67	2	24381198
Pubmed	Quantitative Trait Locus Mapping of Macrophage Cholesterol Metabolism and CRISPR/Cas9 Editing Implicate an ACAT1 Truncation as a Causal Modifier Variant.	SPP1 CASP1	3.28e-04	14	67	2	29097366
Pubmed	LINKIN, a new transmembrane protein necessary for cell adhesion.	ALG5 POLR2E NAP1L1 RCN1 TRIM21 HDLBP	3.28e-04	480	67	6	25437307
Pubmed	The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer.	NAP1L1 MCM3 HUWE1	3.56e-04	71	67	3	29346117
Pubmed	Phosphorylation of the RAP74 subunit of TFIIF correlates with Tat-activated transcription of the HIV-1 long terminal repeat.	POLR2E TAF1	3.78e-04	15	67	2	10704353
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	TRIO OTUB1 CYB5R3 NAP1L1 ACIN1 MCM3 HUWE1 EDC4 SF3B2 HDLBP	3.82e-04	1425	67	10	30948266
Pubmed	Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations.	OTUB1 HUWE1	4.31e-04	16	67	2	25723849
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	RELCH POLR2E NAP1L1 RCN1 MACF1 MCM3 HUWE1 EDC4 TNS3 HDLBP	4.50e-04	1455	67	10	22863883
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	TRIM26 ACIN1 MPHOSPH10 HUWE1 EDC4	4.58e-04	332	67	5	25693804
Pubmed	Tagging genes with cassette-exchange sites.	RELCH ZFAT OTUB1 CYB5R3 MACF1	4.77e-04	335	67	5	15741177
Pubmed	RBM4 dictates ESCC cell fate switch from cellular senescence to glutamine-addiction survival through inhibiting LKB1-AMPK-axis.	TRIM26 HUWE1	4.88e-04	17	67	2	37080995
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	POLR2E ACIN1 EDC4 SF3B2 TP53BP1	5.17e-04	341	67	5	32971831
Pubmed	TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity.	TRIM26 TRIM21	5.48e-04	18	67	2	23077300
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	ALG5 POLR2E TRIM21 MPHOSPH10 EDC4 SF3B2 HDLBP	6.16e-04	754	67	7	35906200
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	ACIN1 EDC4 ATP1A2 HDLBP	6.36e-04	202	67	4	24639526
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	TRIM26 ARID2 POLR2E WRN ACIN1 MACF1 MPHOSPH10	6.41e-04	759	67	7	35915203
Pubmed	The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.	PHKA2 ACIN1 TRIM21 HDLBP	6.48e-04	203	67	4	35012549
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	SORBS2 PPP1R15B POLR2E NAP1L1 ACIN1	6.68e-04	361	67	5	30344098
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	SORBS2 MACF1	6.79e-04	20	67	2	21689717
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	PALS1 POLR2E OTUB1 WRN TRIM21 MPHOSPH9 HUWE1 TP53BP1	6.83e-04	1005	67	8	19615732
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SORBS2 ACIN1 MCM3 HUWE1 SF3B2 TP53BP1 HDLBP	7.19e-04	774	67	7	15302935
Interaction	SUMO2 interactions	TRIM26 ARID2 LRRK2 WRN NAP1L1 ACIN1 MCM3 TAF1 HUWE1 EDC4 SF3B2 TP53BP1 HDLBP	4.22e-08	591	65	13	int:SUMO2
Interaction	TNIK interactions	SHANK1 PALS1 SORBS2 TRIO MACF1 HUWE1 EDC4 TP53BP1 HDLBP	3.53e-06	381	65	9	int:TNIK
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	TRIO ARHGEF38 ARHGEF18	4.82e-04	66	42	3	722
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STON1 PAM MACF1 ATP1A2 HDLBP	6.87e-06	176	67	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	Healthy/Control-pDC\|World / Disease group and Cell class	ZFAT DACH1 ATP1A2 CASC2 FAM221B	8.08e-06	182	67	5	97e0eee10905f2cf2bebb09e474629fc224f4397
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	STON1 ARID2 PPP1R15B EDC4	6.96e-05	146	67	4	1bf67a9416f52198931b912a31be4bab09fefd19
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PHKA2 ZFAT NMRAL1 MCM3	9.22e-05	157	67	4	eea53cf8d8a607264e1ee00b7a97c94bcf2ac80d
ToppCell	10x5'-blood-Myeloid_Dendritic-pDC\|blood / Manually curated celltypes from each tissue	ZFAT DACH1 CDH13 FAM221B	1.25e-04	170	67	4	59cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NAP1L1 MACF1 MCM3 ATP1A2	1.25e-04	170	67	4	e20568c8f3f17d94de78229617eb2f7e4c5af2bc
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 SPP1 LRRK2 ATP1A2	1.37e-04	174	67	4	667035a11b68745fa8446d6c68214713be42710f
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MACF1 MCM3 ATP1A2 TNS3	1.43e-04	176	67	4	cb8fd56a4f935cdda19d7ab43382cdda7c307667
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PHKA2 ORAI1 CASP1 HLCS	1.43e-04	176	67	4	90f8bb11f339f67f08692a0c33dd420f5cda2861
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	ARID2 PPP1R15B PAM HUWE1	1.43e-04	176	67	4	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	ARID2 PPP1R15B PAM HUWE1	1.46e-04	177	67	4	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	Healthy/Control-pDC\|Healthy/Control / Disease group and Cell class	ZFAT DACH1 ATP1A2 FAM221B	1.49e-04	178	67	4	072b346c6bbd63f00efaceda486400a669b3ec48
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORBS2 STON1 CACHD1 CDH13	1.53e-04	179	67	4	a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCell	5'-Adult-SmallIntestine-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 SPP1 ATP1A2 ALK	1.56e-04	180	67	4	5e6e38ee0758ef2342a6a821c78ed24b57bb7b11
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRK2 RCN1 PAM MACF1	1.56e-04	180	67	4	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	5'-Adult-SmallIntestine-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 SPP1 ATP1A2 ALK	1.56e-04	180	67	4	b88cd7ae922782176c057342d1b9eb9b8e5e7204
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRK2 RCN1 PAM MACF1	1.56e-04	180	67	4	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	5'-Adult-SmallIntestine-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 SPP1 ATP1A2 ALK	1.56e-04	180	67	4	ebd6e719a03f25155fa8181be19469d04d6d10a6
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 SPP1 ATP1A2 TNS3	1.56e-04	180	67	4	38490017dd590e3fcfa7e88d8d15235d55f90cf1
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CRYBB2 DACH1 CACHD1 ATP1A2	1.59e-04	181	67	4	fc51468c74534b60b4e786bd512d0f1c5dc05de7
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SORBS2 LRRK2 ARHGEF38 CACHD1	1.66e-04	183	67	4	6847c1252d6bb105524f812658112517fd351eab
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	SORBS2 LRRK2 ARHGEF38 CACHD1	1.70e-04	184	67	4	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	SORBS2 TRIO PAM MACF1	1.70e-04	184	67	4	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	SORBS2 PAM ATP1A2 CDH13	1.70e-04	184	67	4	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	5'-Adult-LargeIntestine-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 SPP1 ATP1A2 ALK	1.73e-04	185	67	4	f607b6ee579562e2f92103fa5c7053df0170a229
ToppCell	5'-Adult-LargeIntestine-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 SPP1 ATP1A2 ALK	1.73e-04	185	67	4	317f2c854f00aa5957319b818c85eeed7d72ec7f
ToppCell	5'-Adult-LargeIntestine-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 SPP1 ATP1A2 ALK	1.73e-04	185	67	4	7bb8fdfe04f85d25056380ec58222366de323a21
ToppCell	Control-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	TRIO LRRK2 ARHGEF18 TNS3	1.81e-04	187	67	4	4e64be635f445276e71f2937f33f041c3a4204ab
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ARID2 MACF1 HUWE1 TP53BP1	1.84e-04	188	67	4	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RELCH ARID2 LRRK2 CDH13	1.84e-04	188	67	4	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RELCH ARID2 LRRK2 CDH13	1.84e-04	188	67	4	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RELCH ARID2 LRRK2 CDH13	1.84e-04	188	67	4	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SPP1 LRRK2 ARHGEF38 TNS3	1.84e-04	188	67	4	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SORBS2 STX3 TRIO LRRK2	1.88e-04	189	67	4	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAM MACF1 ATP1A2 TNS3	1.96e-04	191	67	4	44a9a6768084dafc641ad455b65862bfd4cc0cb9
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SORBS2 LRRK2 ARHGEF38 CACHD1	1.96e-04	191	67	4	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	ARID2 PPP1R15B MACF1 HUWE1	1.96e-04	191	67	4	9454f642c3621370fa23640b631301346b300950
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRIO RCN1 PAM ATP1A2	1.96e-04	191	67	4	9f478f36a0b895e607e3bb77fa0f9f03cc0f33fc
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SORBS2 LRRK2 ARHGEF38 CACHD1	1.96e-04	191	67	4	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	SORBS2 LRRK2 ARHGEF38 CACHD1	2.00e-04	192	67	4	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	COVID-19-kidney-CNT\|kidney / Disease (COVID-19 only), tissue and cell type	SPP1 ARHGEF38 DACH1 ZNF208	2.00e-04	192	67	4	d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	SORBS2 LRRK2 ARHGEF38 CACHD1	2.00e-04	192	67	4	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	SORBS2 TRIO DACH1 MACF1	2.00e-04	192	67	4	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	NAP1L1 MACF1 CDH13 TNS3	2.00e-04	192	67	4	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	DACH1 MACF1 CDH13 TNS3	2.04e-04	193	67	4	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRIO RCN1 PAM ATP1A2	2.04e-04	193	67	4	051f61156b0e2e95292b2d8377faf3190b50f264
ToppCell	PND01-03-samps-Mesenchymal\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	NAP1L1 MACF1 ATP1A2 TNS3	2.08e-04	194	67	4	4f9bd0ded0dde1df885850714f29e73e992539a5
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature-Adult_Glia\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 SPP1 ATP1A2 ALK	2.08e-04	194	67	4	d429bb5e422a07bd92f0dc48cd51528e8b7d9a72
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 SPP1 ATP1A2 ALK	2.08e-04	194	67	4	bffdf6db0bf3fb338e7bb0789ae7dcde1fce0094
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 SPP1 ATP1A2 ALK	2.08e-04	194	67	4	408dfc7060095972a54ae37ae8105521df6fbbee
ToppCell	PND01-Mesenchymal-Mesenchymal_structural\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NAP1L1 MACF1 ATP1A2 TNS3	2.12e-04	195	67	4	6bb6349d6ec8da094fe1c7c590021989337aeb0b
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NAP1L1 MACF1 ATP1A2 TNS3	2.12e-04	195	67	4	a3b468125e48f072255cede7645f6692298ecf54
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	NAP1L1 MACF1 ATP1A2 TNS3	2.16e-04	196	67	4	54f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NAP1L1 MACF1 ATP1A2 TNS3	2.20e-04	197	67	4	06a0d7062dadda656decaf77dcef9a10b5f2698d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SPP1 LRRK2 ARHGEF38 TNS3	2.20e-04	197	67	4	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon\|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.	NAP1L1 RCN1 DACH1 MCM3	2.20e-04	197	67	4	b59369f78bf99a4154a46c331d4dad737d8a5f38
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NAP1L1 MACF1 ATP1A2 TNS3	2.20e-04	197	67	4	d35c7a36135b5ed6a7bf2f934849678eba2a0177
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 SPP1 ATP1A2 TNS3	2.25e-04	198	67	4	52ddc1f1ed4ac4c3bac794c90b8feb03e3c221c4
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	RCN1 DACH1 MCM3 ATP1A2	2.29e-04	199	67	4	75ff9a5df156c6632883eab79573f1c02c985803
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW10\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	CRYBB2 NAP1L1 DACH1 MCM3	2.29e-04	199	67	4	8e72efcd421639ac36ed036ee13f13de070d361f
ToppCell	Non-neuronal\|World / Primary Cells by Cluster	RCN1 DACH1 MCM3 ATP1A2	2.29e-04	199	67	4	165d9de6cedc79e13bb6fa244e8898a5dacc54ff
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ORAI1 CYB5R3 DACH1 ZNF322	2.33e-04	200	67	4	7034f57e282982c19c13ee8ab78eabaffa069e30
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	PALS1 RCN1 DACH1 ATP1A2	2.33e-04	200	67	4	792fef1f3e47ce5c131fedfad55075fc254aeead
Disease	chemotherapy-induced alopecia, methylcobalamin deficiency type cblE	TRIO CDH13	1.29e-04	8	64	2	EFO_0005400, MONDO_0009354
Disease	Papillary Renal Cell Carcinoma	SHANK1 LRRK2 MLLT10 ALK	1.75e-04	128	64	4	C1306837
Disease	Renal Cell Carcinoma	SHANK1 LRRK2 MLLT10 ALK	1.75e-04	128	64	4	C0007134
Disease	Sarcomatoid Renal Cell Carcinoma	SHANK1 LRRK2 MLLT10 ALK	1.75e-04	128	64	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	SHANK1 LRRK2 MLLT10 ALK	1.75e-04	128	64	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	SHANK1 LRRK2 MLLT10 ALK	1.75e-04	128	64	4	C1266044
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	SHANK1 LRRK2 MLLT10 ALK	3.06e-04	148	64	4	C0279702
Disease	response to olanzapine	ATP1A2 CDH13	4.77e-04	15	64	2	GO_0097333
Disease	BMI-adjusted adiponectin measurement	ALK CDH13	4.77e-04	15	64	2	EFO_0007737
Disease	amyloid-beta measurement, Alzheimer's disease biomarker measurement	RELCH CCDC181	5.45e-04	16	64	2	EFO_0005194, EFO_0006514
Disease	lung carcinoma	ZFAT STON1 TRIM26 ZNF322 TRIM21 TP53BP1	6.20e-04	482	64	6	EFO_0001071
Disease	chronic obstructive pulmonary disease	STON1 TRIM26 ARHGEF38 ZSCAN9 MCM3 MPHOSPH9 HDLBP	7.13e-04	688	64	7	EFO_0000341
Disease	Meningioma	WRN MLLT10	7.73e-04	19	64	2	C0025286
Disease	Uterine leiomyoma	STON1 ZNF208 MLLT10	1.03e-03	91	64	3	HP_0000131
Disease	Ovarian Serous Adenocarcinoma	LRRK2 ALK	1.14e-03	23	64	2	C1335177
Disease	serum albumin measurement	ZFAT TRIM26 MACF1 MLLT10 TP53BP1 HDLBP	1.78e-03	592	64	6	EFO_0004535
Disease	unipolar depression, bipolar disorder, seasonality measurement	HLCS CDH13	1.94e-03	30	64	2	EFO_0003761, EFO_0006876, MONDO_0004985
Disease	upper aerodigestive tract neoplasm	TRIM26 ZSCAN9 ZNF322 TRIM21	2.02e-03	246	64	4	EFO_0004284

Protein segments in the cluster

Peptide	Gene	Start	Entry
RIHHTVEEKEEVTMD	ACIN1	761	Q9UKV3
VLECMEKDHVEPDHV	ARHGEF18	186	Q6ZSZ5
KMEIIDDDVPSFHAH	CRYBB2	121	P43320
ATKMPALHRHEEEKF	ALG5	31	Q9Y673
VAETLTPEEEHHMKR	ARHGEF38	76	Q9NXL2
QHPSLEDMQEVVVHK	ACVR2A	421	P27037
LHVHERKIEVMENPS	ARID2	1256	Q68CP9
YEHLSQPETKRMVEH	CACHD1	666	Q5VU97
RKHFDMPHDIVASED	PAM	776	P19021
VHARTPHAEDMAELV	CDH13	96	P55290
HESKRMHIEKDETPL	DACH1	566	Q9UI36
HPEEFEHMKEIVVLE	RCN1	196	Q15293
IRAIMKDPDDHTVCH	CYB5R3	191	P00387
HEFHSHEDMLVVDPK	SPP1	276	P10451
EEAVMHLDHSDPITR	EDC4	1341	Q6P2E9
LSDMVQEHDEPILKH	NAP1L1	181	P55209
LRTDMEHLSPEHEVI	RELCH	1141	Q9P260
HTRKVVHDAKMTPED	NMRAL1	231	Q9HBL8
HLENEDKDRMIVHVP	HLCS	306	P50747
KESPHERMHRHIELA	ORAI1	161	Q96D31
IIEEPHITMDAEKHP	FAM221B	6	A6H8Z2
DMHHSLPETLEKTFI	MPHOSPH9	221	Q99550
MPEESREDTEFHHKL	LRRK2	516	Q5S007
HFDHAVRMAPVITEE	MPHOSPH10	406	O00566
EVEHMTRHLEESEKA	LRRC45	436	Q96CN5
HIIEDPCTLRHTMEK	HUWE1	1826	Q7Z6Z7
RDEHDSHIKSQPREM	MACF1	3011	Q9UPN3
VDLASPEEHQKHREM	PALS1	21	Q8N3R9
PEQDREISDHVLRMH	MCM3	491	P25205
QEVEPMCKESDHIHI	OTUB1	206	Q96FW1
ETVMEHTKRHSDPDK	CCDC181	56	Q5TID7
HEREDSPQSHVLVMK	ATP1A2	491	P50993
MTTELEAFAHRPEHK	CASP1	211	P29466
EEPSAHHNSIDIKRM	CASC2	41	Q6XLA1
MEDHQHVPIDIQTSK	CDK5RAP3	1	Q96JB5
KEKHEVQMDHRPESV	DONSON	386	Q9NYP3
REMTPHEIKFAVHVE	PHKA2	1111	P46019
EHELVPEHVVMTKEE	POLR2E	141	P19388
TEHEPVIKSRMIEEF	TAF1	371	P21675
SISEEVMDLAKHLPH	WRN	256	Q14191
KDRETDILDDEMPHH	TNS3	471	Q68CZ2
EEEHSLLRMDPKHCR	PPP1R15B	326	Q5SWA1
VMHTVDHVEKARDET	STX3	236	Q13277
MLKHERARHENTEEP	SORBS2	671	O94875
SDKDIELLPTDMRHH	PVALEF	21	A0A1B0GWK0
VTRHPDMDEAVHKKA	SHANK1	756	Q9Y566
EVDECHMDPESHKVI	ALK	991	Q9UM73
RPVSLEDEVSHSMKE	MLLT10	6	P55197
HMDRDTVKACLPDEH	TEPP	106	Q6URK8
EMHDVTAQDPKLLVH	SF3B2	476	Q13435
ELLSHVSEKHMEEGV	ZFAT	26	Q9P243
SHLPEMHIFQTEEKI	ZNF761	146	Q86XN6
QTLDVHMREKHPESN	ZFHX2	466	Q9C0A1
HSKTEVVHEPDIEQM	STON1	361	Q9Y6Q2
EHELVHVMERSLSPS	FSBP	181	O95073
SDLIVHQRIHMEEKP	ZNF322	306	Q6U7Q0
RKRMPHEVTHSMEEI	UBE2U	236	Q5VVX9
HEVTHSMEEIKLCPT	UBE2U	241	Q5VVX9
VLDQEEAMEIKEHHP	TP53BP1	641	Q12888
ESREHRPHTAVLMEK	TRIM26	126	Q12899
QSRKHRDHAMVPLEE	TRIM21	116	P19474
KRHEMVEESPVICSH	ZNF208	66	O43345
PHVEARAASMETTEK	TEX13A	226	Q9BXU3
EEMDVREKGPLVFHH	PRR29	96	P0C7W0
VEKLSTHHLRDFMDP	TBC1D20	166	Q96BZ9
ERELDEPQHEMVAHR	ZSCAN9	131	O15535
VEDSMLVDPKHHRHF	HDLBP	801	Q00341
SETDHVTPMISKHLE	TRIO	1051	O75962
RARHEPVNHSDMVDK	MYO7A	931	Q13402