Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR5P2 ADGRG5 OR2B2 OR2T27 F2RL3 OR9I1 OR13C3 OR13C4 ADGRV1 OR14C36 OR2T10 OR2T34 GRM1 S1PR1 OR14A16 OR8B3 OR2T3 OR2K2 ADRA2A OR13A1 MRGPRG OR8B2

2.84e-108849922GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR5P2 ADGRG5 OR2B2 OR2T27 F2RL3 OR9I1 OR13C3 C17orf99 OR13C4 SOSTDC1 ADGRV1 OR14C36 OR2T10 OR2T34 GRM1 S1PR1 OR14A16 OR8B3 OR2T3 OR2K2 ADRA2A OR13A1 MRGPRG OR8B2 UNC5D PLXNA1

1.34e-0913539926GO:0004888
GeneOntologyMolecularFunctionolfactory receptor activity

OR5P2 OR2B2 OR2T27 OR9I1 OR13C3 OR13C4 OR14C36 OR2T10 OR2T34 OR14A16 OR8B3 OR2T3 OR2K2 OR13A1 OR8B2

3.32e-094319915GO:0004984
GeneOntologyMolecularFunctionalpha-1B adrenergic receptor binding

ADRA2A ARRB1 ARRB2

1.18e-073993GO:0031692
GeneOntologyMolecularFunctionodorant binding

OR5P2 OR9I1 OR14C36 OR14A16 OR8B3 OR13A1 OR8B2

3.27e-06127997GO:0005549
GeneOntologyMolecularFunctionadrenergic receptor binding

NEDD4 ADRA2A ARRB1 ARRB2

5.60e-0624994GO:0031690
GeneOntologyMolecularFunctionalpha-1A adrenergic receptor binding

ARRB1 ARRB2

2.43e-052992GO:0031691
GeneOntologyMolecularFunctionfollicle-stimulating hormone receptor binding

ARRB1 ARRB2

7.28e-053992GO:0031762
GeneOntologyMolecularFunctionangiotensin receptor binding

ARRB1 ARRB2

1.07e-0310992GO:0031701
GeneOntologyMolecularFunctionthioesterase binding

ADRA2A CDC42

1.07e-0310992GO:0031996
GeneOntologyMolecularFunctionarrestin family protein binding

ARRB1 ARRB2

1.55e-0312992GO:1990763
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR5P2 ADGRG5 OR2B2 OR2T27 F2RL3 OR9I1 OR13C3 OR13C4 ADGRV1 OR14C36 OR2T10 OR2T34 GRM1 S1PR1 OR14A16 GSK3A OR8B3 OR2T3 OR2K2 ADRA2A ARRB1 ARRB2 OR13A1 MRGPRG AKAP13 OR8B2 CDC42 DNM2 PLCE1

2.46e-1213959529GO:0007186
GeneOntologyBiologicalProcessdetection of stimulus

OR5P2 OR2B2 OR2T27 OR9I1 OR13C3 OR13C4 ADGRV1 OR14C36 OR2T10 OR2T34 PKD1L2 OR14A16 OR8B3 OR2T3 OR2K2 ARRB1 ARRB2 OR13A1 OR8B2

6.40e-107229519GO:0051606
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR5P2 OR2B2 OR2T27 OR9I1 OR13C3 OR13C4 ADGRV1 OR14C36 OR2T10 OR2T34 OR14A16 OR8B3 OR2T3 OR2K2 ARRB2 OR13A1 OR8B2

1.20e-095829517GO:0050906
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR5P2 OR2B2 OR2T27 OR9I1 OR13C3 OR13C4 OR14C36 OR2T10 OR2T34 OR14A16 OR8B3 OR2T3 OR2K2 OR13A1 OR8B2

1.23e-094329515GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR5P2 OR2B2 OR2T27 OR9I1 OR13C3 OR13C4 OR14C36 OR2T10 OR2T34 OR14A16 OR8B3 OR2T3 OR2K2 OR13A1 OR8B2

3.34e-094659515GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR5P2 OR2B2 OR2T27 OR9I1 OR13C3 OR13C4 OR14C36 OR2T10 OR2T34 OR14A16 OR8B3 OR2T3 OR2K2 OR13A1 OR8B2

5.90e-094859515GO:0050907
GeneOntologyBiologicalProcesssensory perception

OR5P2 OR2B2 OR2T27 OR9I1 OR13C3 OR13C4 ADGRV1 OR14C36 OR2T10 OR2T34 GRM1 TECTA OR14A16 OR8B3 OR2T3 OR2K2 ADRA2A ARRB1 ARRB2 OR13A1 OR8B2

1.37e-0810729521GO:0007600
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR5P2 OR2B2 OR2T27 OR9I1 OR13C3 OR13C4 OR14C36 OR2T10 OR2T34 OR14A16 OR8B3 OR2T3 OR2K2 OR13A1 OR8B2

1.66e-085249515GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR5P2 OR2B2 OR2T27 OR9I1 OR13C3 OR13C4 OR14C36 OR2T10 OR2T34 OR14A16 OR8B3 OR2T3 OR2K2 OR13A1 OR8B2

2.92e-085479515GO:0007606
GeneOntologyBiologicalProcesssmall GTPase-mediated signal transduction

F2RL3 RALGAPB USP8 ADRA2A ARRB1 SSX2IP AKAP13 CDC42 DNM2 CDON PLCE1

3.71e-055389511GO:0007264
GeneOntologyBiologicalProcessG protein-coupled receptor internalization

ARRB1 ARRB2 DNM2

1.19e-0421953GO:0002031
GeneOntologyBiologicalProcessregulation of protein catabolic process at postsynapse, modulating synaptic transmission

NEDD4 USP8

2.08e-045952GO:0099576
GeneOntologyCellularComponentneuron spine

GRM1 NEDD4 USP8 ARRB1 ARRB2 CNTNAP2 CDC42 ATP2B1

2.14e-05247988GO:0044309
GeneOntologyCellularComponentdendritic spine

GRM1 NEDD4 USP8 ARRB1 ARRB2 CDC42 ATP2B1

1.44e-04242987GO:0043197
GeneOntologyCellularComponentglutamatergic synapse

NPTX1 GRM1 NEDD4 USP8 ADRA2A ARRB2 CNTNAP2 DIXDC1 CDC42 ATP2B1 PLXNA1 DNM2

4.36e-048179812GO:0098978
DomainGPCR_Rhodpsn_7TM

OR5P2 OR2B2 OR2T27 F2RL3 OR9I1 OR13C3 OR13C4 OR14C36 OR2T10 OR2T34 S1PR1 OR14A16 OR8B3 OR2T3 OR2K2 ADRA2A OR13A1 MRGPRG OR8B2

9.45e-106709519IPR017452
Domain7tm_1

OR5P2 OR2B2 OR2T27 F2RL3 OR9I1 OR13C3 OR13C4 OR14C36 OR2T10 OR2T34 S1PR1 OR14A16 OR8B3 OR2T3 OR2K2 ADRA2A OR13A1 MRGPRG OR8B2

1.12e-096779519PF00001
DomainOlfact_rcpt

OR5P2 OR2B2 OR2T27 OR9I1 OR13C3 OR13C4 OR14C36 OR2T10 OR2T34 OR14A16 OR8B3 OR2T3 OR2K2 OR13A1 OR8B2

1.28e-093939515IPR000725
DomainG_PROTEIN_RECEP_F1_1

OR5P2 OR2B2 OR2T27 F2RL3 OR9I1 OR13C3 OR13C4 OR14C36 OR2T10 OR2T34 S1PR1 OR14A16 OR8B3 OR2T3 OR2K2 ADRA2A OR13A1 MRGPRG OR8B2

1.36e-096859519PS00237
DomainG_PROTEIN_RECEP_F1_2

OR5P2 OR2B2 OR2T27 F2RL3 OR9I1 OR13C3 OR13C4 OR14C36 OR2T10 OR2T34 S1PR1 OR14A16 OR8B3 OR2T3 OR2K2 ADRA2A OR13A1 MRGPRG OR8B2

1.57e-096919519PS50262
DomainGPCR_Rhodpsn

OR5P2 OR2B2 OR2T27 F2RL3 OR9I1 OR13C3 OR13C4 OR14C36 OR2T10 OR2T34 S1PR1 OR14A16 OR8B3 OR2T3 OR2K2 ADRA2A OR13A1 MRGPRG OR8B2

1.61e-096929519IPR000276
DomainArrestin_N

ARRB1 ARRB2

1.53e-044952IPR014753
DomainArrestin

ARRB1 ARRB2

1.53e-044952IPR000698
Domain-

ARRB1 ARRB2

1.53e-0449522.60.40.840
DomainArrestin_CS

ARRB1 ARRB2

1.53e-044952IPR017864
DomainARRESTINS

ARRB1 ARRB2

1.53e-044952PS00295
Domain-

ARRB1 ARRB2

5.29e-0479522.60.40.640
DomainGPS

ADGRG5 ADGRV1 PKD1L2

6.80e-0434953SM00303
DomainCalx_beta

ADGRV1 FREM3

7.03e-048952SM00237
DomainArrestin_C

ARRB1 ARRB2

7.03e-048952IPR014752
DomainGPS

ADGRG5 ADGRV1 PKD1L2

7.42e-0435953PF01825
DomainGPS

ADGRG5 ADGRV1 PKD1L2

8.06e-0436953PS50221
DomainGPS

ADGRG5 ADGRV1 PKD1L2

8.74e-0437953IPR000203
DomainCalx_beta

ADGRV1 FREM3

9.00e-049952IPR003644
DomainCalx-beta

ADGRV1 FREM3

9.00e-049952PF03160
DomainArrestin-like_N

ARRB1 ARRB2

1.12e-0310952IPR011021
DomainArrestin_C-like

ARRB1 ARRB2

1.12e-0310952IPR011022
DomainArrestin_C

ARRB1 ARRB2

1.12e-0310952PF02752
DomainArrestin_N

ARRB1 ARRB2

1.12e-0310952PF00339
DomainArrestin_C

ARRB1 ARRB2

1.12e-0310952SM01017
Domain7TM_GPCR_Srsx

OR2T34 S1PR1 OR2T3 ADRA2A

2.57e-03112954SM01381
DomainPI3/4_kinase_CS

SMG1 PIK3C2G

2.57e-0315952IPR018936
Domain-

SMG1 PIK3C2G

2.93e-03169521.10.1070.11
DomainPI3Kc

SMG1 PIK3C2G

2.93e-0316952SM00146
DomainHEAT_type_2

PIK3R4 MROH1

3.31e-0317952IPR021133
DomainPI3/4_kinase_cat_dom

SMG1 PIK3C2G

3.71e-0318952IPR000403
DomainPI3_PI4_kinase

SMG1 PIK3C2G

3.71e-0318952PF00454
DomainPI3_4_KINASE_3

SMG1 PIK3C2G

3.71e-0318952PS50290
DomainPI3_4_KINASE_1

SMG1 PIK3C2G

3.71e-0318952PS00915
DomainPI3_4_KINASE_2

SMG1 PIK3C2G

3.71e-0318952PS00916
DomainUSP_CS

USP17L7 USP29 USP8

4.63e-0366953IPR018200
DomainHEAT_REPEAT

SMG1 PIK3R4 MROH1

5.46e-0370953PS50077
DomainUSP_1

USP17L7 USP29 USP8

5.46e-0370953PS00972
DomainUCH

USP17L7 USP29 USP8

5.68e-0371953PF00443
DomainUSP_2

USP17L7 USP29 USP8

5.68e-0371953PS00973
DomainUSP_3

USP17L7 USP29 USP8

5.90e-0372953PS50235
DomainUSP_dom

USP17L7 USP29 USP8

5.90e-0372953IPR028889
DomainPeptidase_C19_UCH

USP17L7 USP29 USP8

5.90e-0372953IPR001394
DomainC2

WWC3 NEDD4 PIK3C2G PLCE1

5.98e-03142954PS50004
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR5P2 OR2B2 OR2T27 OR9I1 OR13C3 OR13C4 OR14C36 OR2T10 OR2T34 OR14A16 OR8B3 OR2T3 OR2K2 OR13A1 OR8B2

5.97e-094177715M4072
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR5P2 OR2B2 OR2T27 OR9I1 OR13C3 OR13C4 OR14C36 OR2T10 OR2T34 OR14A16 OR2T3 OR2K2 ARRB2 OR13A1

2.03e-083897714M14091
PathwayREACTOME_SENSORY_PERCEPTION

OR5P2 OR2B2 OR2T27 OR9I1 OR13C3 OR13C4 OR14C36 OR2T10 OR2T34 GRM1 OR14A16 OR8B3 OR2T3 OR2K2 OR13A1 OR8B2 ATP2B1

4.19e-086367717M41834
PathwayREACTOME_ACTIVATION_OF_SMO

ARRB1 ARRB2 CDON

5.46e-0514773MM15228
PathwayREACTOME_ACTIVATION_OF_SMO

ARRB1 ARRB2 CDON

1.21e-0418773M27500
Pubmed

The human olfactory receptor gene family.

OR5P2 OR2B2 OR2T27 OR9I1 OR13C3 OR13C4 OR14C36 OR2T10 OR2T34 OR14A16 OR8B3 OR2K2 OR13A1 OR8B2

4.66e-10541991414983052
Pubmed

Agonist-stimulated and tonic internalization of metabotropic glutamate receptor 1a in human embryonic kidney 293 cells: agonist-stimulated endocytosis is beta-arrestin1 isoform-specific.

GRM1 ARRB1 ARRB2

2.24e-08399311723231
Pubmed

Distinct roles for β-arrestin2 and arrestin-domain-containing proteins in β2 adrenergic receptor trafficking.

NEDD4 ARRB1 ARRB2

4.45e-07699323208550
Pubmed

Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor.

NEDD4 ARRB1 ARRB2

4.45e-07699318544533
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR5P2 OR2B2 OR9I1 OR13C3 OR14C36 OR8B3 OR2K2 OR13A1 OR8B2

5.87e-0734099911875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR5P2 OR2B2 OR9I1 OR13C3 OR14C36 OR8B3 OR2K2 OR13A1 OR8B2

5.87e-0734099911802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR5P2 OR2B2 OR9I1 OR13C3 OR14C36 OR8B3 OR2K2 OR13A1 OR8B2

6.31e-0734399932295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR5P2 OR2B2 OR9I1 OR13C3 OR14C36 OR8B3 OR2K2 OR13A1 OR8B2

6.79e-0734699914611657
Pubmed

MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors.

NEDD4 ARRB1 ARRB2

7.77e-07799323166351
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RALGAPB LYST GSK3A NEDD4 PIK3R4 USP8 SSX2IP ZBTB21 AKAP13 CKAP2 ATP2B1 UTRN PCM1

1.04e-06861991336931259
Pubmed

An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior.

GSK3A ARRB1 ARRB2

1.24e-06899316051150
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

NBAS SMG7 SSX2IP CKAP2 CEP97 PCM1 DNM2

7.94e-0625199729778605
Pubmed

Agonist-selective, receptor-specific interaction of human P2Y receptors with beta-arrestin-1 and -2.

ARRB1 ARRB2

8.02e-06299218703513
Pubmed

Msd1/SSX2IP-dependent microtubule anchorage ensures spindle orientation and primary cilia formation.

SSX2IP PCM1

8.02e-06299224397932
Pubmed

Beta-arrestins 1 and 2 are associated with nicotine dependence in European American smokers.

ARRB1 ARRB2

8.02e-06299217579607
Pubmed

Beta-arrestin 1 regulation of reward-motivated behaviors and glutamatergic function.

ARRB1 ARRB2

8.02e-06299228973019
Pubmed

β-Arrestin1 enhances hepatocellular carcinogenesis through inflammation-mediated Akt signalling.

ARRB1 ARRB2

8.02e-06299226077142
Pubmed

Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo.

ARRB1 ARRB2

8.02e-06299217426148
Pubmed

β-Arrestin-dependent ERK signaling reduces anxiety-like and conditioned fear-related behaviors in mice.

ARRB1 ARRB2

8.02e-06299234344831
Pubmed

Beta-arrestin-1 protein represses diet-induced obesity.

ARRB1 ARRB2

8.02e-06299221543334
Pubmed

LSD-stimulated behaviors in mice require β-arrestin 2 but not β-arrestin 1.

ARRB1 ARRB2

8.02e-06299234480046
Pubmed

ARRB2 (β-Arrestin-2) Deficiency Alters Fluid Homeostasis and Blood Pressure Regulation.

ARRB1 ARRB2

8.02e-06299236215165
Pubmed

Critical regulation of CD4+ T cell survival and autoimmunity by beta-arrestin 1.

ARRB1 ARRB2

8.02e-06299217618287
Pubmed

Specificity of arrestin subtypes in regulating airway smooth muscle G protein-coupled receptor signaling and function.

ARRB1 ARRB2

8.02e-06299226103985
Pubmed

β-Arrestin 1 and 2 similarly influence μ-opioid receptor mobility and distinctly modulate adenylyl cyclase activity.

ARRB1 ARRB2

8.02e-06299234450275
Pubmed

G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization.

ARRB1 ARRB2

8.02e-0629929668034
Pubmed

Metabolic effects of skeletal muscle-specific deletion of beta-arrestin-1 and -2 in mice.

ARRB1 ARRB2

8.02e-06299231622341
Pubmed

Beta-arrestin1 and beta-arrestin2 are differentially required for phosphorylation-dependent and -independent internalization of delta-opioid receptors.

ARRB1 ARRB2

8.02e-06299216181421
Pubmed

LAPTM4α is targeted from the Golgi to late endosomes/lysosomes in a manner dependent on the E3 ubiquitin ligase Nedd4-1 and ESCRT proteins.

LAPTM4A NEDD4

8.02e-06299233836347
Pubmed

Increased expression of beta-arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation.

ARRB1 ARRB2

8.02e-06299221855149
Pubmed

Beta-arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration.

ARRB1 ARRB2

8.02e-06299218519945
Pubmed

Regulation of mitochondrial oxidative stress by β-arrestins in cultured human cardiac fibroblasts.

ARRB1 ARRB2

8.02e-06299226449263
Pubmed

The role of beta-arrestins in the formyl peptide receptor-like 1 internalization and signaling.

ARRB1 ARRB2

8.02e-06299217594911
Pubmed

Light-dependent regulation of the transcriptional activity of the mammalian gene for arrestin.

ARRB1 ARRB2

8.02e-0629927932878
Pubmed

Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference.

ARRB1 ARRB2

8.02e-06299212582207
Pubmed

Contributions of protein kinases and β-arrestin to termination of protease-activated receptor 2 signaling.

ARRB1 ARRB2

8.02e-06299226927499
Pubmed

β-Arrestin prevents cell apoptosis through pro-apoptotic ERK1/2 and p38 MAPKs and anti-apoptotic Akt pathways.

ARRB1 ARRB2

8.02e-06299222699970
Pubmed

beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice.

ARRB1 ARRB2

8.02e-06299219349687
Pubmed

β-arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix.

ARRB1 ARRB2

8.02e-06299221411739
Pubmed

The Two β-Arrestins Regulate Distinct Metabolic Processes: Studies with Novel Mutant Mouse Models.

ARRB1 ARRB2

8.02e-06299235008921
Pubmed

Deficiency of β-Arrestin 2 in Dendritic Cells Contributes to Autoimmune Diseases.

ARRB1 ARRB2

8.02e-06299230541881
Pubmed

β-Arrestins regulate human cardiac fibroblast transformation and collagen synthesis in adverse ventricular remodeling.

ARRB1 ARRB2

8.02e-06299225134464
Pubmed

beta-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking.

ARRB1 ARRB2

8.02e-06299211171997
Pubmed

Regulation of lipopolysaccharide-induced inflammatory response and endotoxemia by beta-arrestins.

ARRB1 ARRB2

8.02e-06299220589830
Pubmed

β-Arrestin2 mediates the initiation and progression of myeloid leukemia.

ARRB1 ARRB2

8.02e-06299222773819
Pubmed

Beta-arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression.

ARRB1 ARRB2

8.02e-06299217418896
Pubmed

β-Arrestin2 mediates progression of murine primary myelofibrosis.

ARRB1 ARRB2

8.02e-06299229263312
Pubmed

β-Arrestins Regulate Stem Cell-Like Phenotype and Response to Chemotherapy in Bladder Cancer.

ARRB1 ARRB2

8.02e-06299230787175
Pubmed

beta-Arrestins modulate Adenovirus-vector-induced innate immune responses: differential regulation by beta-arrestin-1 and beta-arrestin-2.

ARRB1 ARRB2

8.02e-06299219896992
Pubmed

Unique Roles of β-Arrestin in GPCR Trafficking Revealed by Photoinducible Dimerizers.

ARRB1 ARRB2

8.02e-06299229330504
Pubmed

β-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy.

ARRB1 ARRB2

8.02e-06299227054338
Pubmed

Transduction of group I mGluR-mediated synaptic plasticity by β-arrestin2 signalling.

ARRB1 ARRB2

8.02e-06299227886171
Pubmed

Hepatic β-arrestin 2 is essential for maintaining euglycemia.

ARRB1 ARRB2

8.02e-06299228650340
Pubmed

Molecular analysis of human beta-arrestin-1: cloning, tissue distribution, and regulation of expression. Identification of two isoforms generated by alternative splicing.

ARRB1 ARRB2

8.02e-0629928486659
Pubmed

Scaffolding mechanism of arrestin-2 in the cRaf/MEK1/ERK signaling cascade.

ARRB1 ARRB2

8.02e-06299234507982
Pubmed

β-arrestin expression in corticotroph tumor cells is modulated by glucocorticoids.

ARRB1 ARRB2

8.02e-06299232027601
Pubmed

Arrestin-2 differentially regulates PAR4 and ADP receptor signaling in platelets.

F2RL3 ARRB2

8.02e-06299221106537
Pubmed

β-arrestins negatively control human adrenomedullin type 1-receptor internalization.

ARRB1 ARRB2

8.02e-06299228427767
Pubmed

Mammalian α arrestins link activated seven transmembrane receptors to Nedd4 family e3 ubiquitin ligases and interact with β arrestins.

NEDD4 ARRB1 ARRB2

9.93e-061599323236378
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ST7 RALGAPB ADGRV1 TECTA PPARGC1B ARRB1 ARRB2 SMG7 AKAP13 PHF14 CKAP2 ATP2B1 UTRN KDM6A PCM1

2.03e-051489991528611215
Pubmed

The ATP-gated P2X1 receptor plays a pivotal role in activation of aspirin-treated platelets by thrombin and epinephrine.

F2RL3 ADRA2A

2.40e-05399218480058
Pubmed

Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation.

ARRB1 ARRB2

2.40e-05399218787115
Pubmed

Identification of receptor binding-induced conformational changes in non-visual arrestins.

ARRB1 ARRB2

2.40e-05399224867953
Pubmed

Neuronal pentraxin 1 induction in hypoxic-ischemic neuronal death is regulated via a glycogen synthase kinase-3α/β dependent mechanism.

NPTX1 GSK3A

2.40e-05399221130869
Pubmed

β-Arrestin scaffolds and signaling elements essential for the obestatin/GPR39 system that determine the myogenic program in human myoblast cells.

ARRB1 ARRB2

2.40e-05399226211463
Pubmed

β-Arrestin signal complex plays a critical role in adipose differentiation.

ARRB1 ARRB2

2.40e-05399223557604
Pubmed

The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42.

ARRB2 CDC42

2.40e-05399219416857
Pubmed

β-Arrestin1 and 2 differentially regulate PACAP-induced PAC1 receptor signaling and trafficking.

ARRB1 ARRB2

2.40e-05399229734363
Pubmed

Essential requirement for β-arrestin2 in mouse intestinal tumors with elevated Wnt signaling.

ARRB1 ARRB2

2.40e-05399222315403
Pubmed

Increased susceptibility to light damage in an arrestin knockout mouse model of Oguchi disease (stationary night blindness).

ARRB1 ARRB2

2.40e-05399210549660
Pubmed

Subcellular localization of beta-arrestins is determined by their intact N domain and the nuclear export signal at the C terminus.

ARRB1 ARRB2

2.40e-05399212538596
Pubmed

Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins.

ARRB1 ARRB2

2.40e-05399217272726
Pubmed

Beta-arrestins regulate a Ral-GDS Ral effector pathway that mediates cytoskeletal reorganization.

ARRB1 ARRB2

2.40e-05399212105416
Pubmed

GSK3α phosphorylates dynamin-2 to promote GLUT4 endocytosis in muscle cells.

GSK3A DNM2

2.40e-05399236445308
Pubmed

Distinct functional outputs of PTEN signalling are controlled by dynamic association with β-arrestins.

ARRB1 ARRB2

2.40e-05399221642958
Pubmed

Agonist-Specific Recruitment of Arrestin Isoforms Differentially Modify Delta Opioid Receptor Function.

ARRB1 ARRB2

2.40e-05399227013682
Pubmed

Extracellular α-synuclein induces sphingosine 1-phosphate receptor subtype 1 uncoupled from inhibitory G-protein leaving β-arrestin signal intact.

S1PR1 ARRB2

2.40e-05399228300069
Pubmed

Beta-arrestin 2 is required for lysophosphatidic acid-induced NF-kappaB activation.

ARRB1 ARRB2

2.40e-05399218952848
Pubmed

beta-Arrestins scaffold cofilin with chronophin to direct localized actin filament severing and membrane protrusions downstream of protease-activated receptor-2.

ARRB1 ARRB2

2.40e-05399220207744
Pubmed

Bradykinin-activated contractile signalling pathways in human myometrial cells are differentially regulated by arrestin proteins.

ARRB1 ARRB2

2.40e-05399225766502
Pubmed

Arrestin serves as a molecular switch, linking endogenous alpha2-adrenergic receptor to SRC-dependent, but not SRC-independent, ERK activation.

ADRA2A ARRB2

2.40e-05399216809338
Pubmed

Promyogenic function of Integrin/FAK signaling is mediated by Cdo, Cdc42 and MyoD.

CDC42 CDON

2.40e-05399221397010
Pubmed

β-Arrestin2 is a critical component of the GPCR-eNOS signalosome.

ARRB1 ARRB2

2.40e-05399232404425
Pubmed

Preferential β-arrestin signalling at low receptor density revealed by functional characterization of the human FSH receptor A189 V mutation.

ARRB1 ARRB2

2.40e-05399220801186
Pubmed

The transient receptor potential vanilloid 4 channel modulates uterine tone during pregnancy.

ARRB1 ARRB2

2.40e-05399226702092
Pubmed

The unique amino-terminal region of the PDE4D5 cAMP phosphodiesterase isoform confers preferential interaction with beta-arrestins.

ARRB1 ARRB2

2.40e-05399214500724
Pubmed

A family of retinal S-antigens (arrestins) and their genes: comparative analysis of human, mouse, rat, bovine and Drosophila.

ARRB1 ARRB2

2.40e-0539921458825
Pubmed

Beta-arrestin-1 protein represses adipogenesis and inflammatory responses through its interaction with peroxisome proliferator-activated receptor-gamma (PPARgamma).

ARRB1 ARRB2

2.40e-05399221700709
Pubmed

beta-Arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha.

ARRB1 ARRB2

2.40e-05399215173580
Pubmed

β-arrestin is critical for early shear stress-induced Akt/eNOS activation in human vascular endothelial cells.

ARRB1 ARRB2

2.40e-05399228062183
Pubmed

Quantification of beta adrenergic receptor subtypes in beta-arrestin knockout mouse airways.

ARRB1 ARRB2

2.40e-05399225658948
Pubmed

KISS1R signals independently of Gαq/11 and triggers LH secretion via the β-arrestin pathway in the male mouse.

ARRB1 ARRB2

2.40e-05399225147978
Pubmed

Functional antagonism of β-arrestin isoforms balance IGF-1R expression and signalling with distinct cancer-related biological outcomes.

ARRB1 ARRB2

2.40e-05399228581517
Pubmed

β-Arrestin 1 and 2 and G protein-coupled receptor kinase 2 expression in pituitary adenomas: role in the regulation of response to somatostatin analogue treatment in patients with acromegaly.

ARRB1 ARRB2

2.40e-05399224169548
Pubmed

Distinct roles of β-arrestin 1 and β-arrestin 2 in ORG27569-induced biased signaling and internalization of the cannabinoid receptor 1 (CB1).

ARRB1 ARRB2

2.40e-05399223449980
Pubmed

Beneficial metabolic role of β-arrestin-1 expressed by AgRP neurons.

ARRB1 ARRB2

2.40e-05399232537493
Pubmed

Opposing effects of beta-arrestin1 and beta-arrestin2 on activation and degradation of Src induced by protease-activated receptor 1.

ARRB1 ARRB2

2.40e-05399216580177
Pubmed

Arrestin/clathrin interaction. Localization of the arrestin binding locus to the clathrin terminal domain.

ARRB1 ARRB2

2.40e-0539929169477
Pubmed

Direct binding of beta-arrestins to two distinct intracellular domains of the delta opioid receptor.

ARRB1 ARRB2

2.40e-05399211259507
Pubmed

Beta-arrestin-dependent parathyroid hormone-stimulated extracellular signal-regulated kinase activation and parathyroid hormone type 1 receptor internalization.

ARRB1 ARRB2

2.40e-05399217525124
Cytoband1q44

OR2T27 OR14C36 OR2T10 OR2T34 OR14A16 OR2T3

1.54e-071109961q44
CytobandEnsembl 112 genes in cytogenetic band chr1q44

OR2T27 OR14C36 OR2T10 OR2T34 OR14A16 OR2T3

3.78e-07128996chr1q44
Cytoband6q24

GRM1 UTRN

1.28e-0489926q24
GeneFamilyOlfactory receptors, family 2

OR2B2 OR2T27 OR2T10 OR2T34 OR2T3 OR2K2

5.37e-06113716149
GeneFamilyClassical arrestins

ARRB1 ARRB2

9.08e-0547121312
GeneFamilyOlfactory receptors, family 13

OR13C3 OR13C4 OR13A1

9.71e-0523713162
GeneFamilyOlfactory receptors, family 14

OR14C36 OR14A16

3.15e-047712163
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 LYST USP8 STXBP6 ATP2B1 KDM6A PCM1

1.72e-07182997f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 PKD1L2 GRM1 PIK3C2G DNAH9 UNC5D PLCE1

1.85e-071849972cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 PKD1L2 GRM1 PIK3C2G DNAH9 UNC5D PLCE1

1.85e-07184997ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 PKD1L2 GRM1 PIK3C2G DNAH9 UNC5D PLCE1

1.85e-071849972b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 LYST USP8 STXBP6 ATP2B1 KDM6A PCM1

1.92e-071859977adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 TECTA PIK3C2G SPHKAP CNTNAP2 DNAH9

1.57e-06160996c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 TECTA PIK3C2G SPHKAP CNTNAP2 DNAH9

1.57e-0616099625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECM2 LYST NEDD4 STXBP6 KDM6A PCM1

2.73e-06176996749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 LYST USP8 UTRN KDM6A PCM1

3.52e-061849961154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellNS-critical-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ST7 STXBP6 SSX2IP ZBTB21 CNTNAP2 PLCE1

4.24e-061909967be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

TRAPPC11 S1PR1 ADRA2A STXBP6 UTRN CDON

5.53e-06199996358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellPND07-28-samps-Mesenchymal-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ADRA2A NAPRT FHIP1A CDON PLCE1

2.58e-05156995574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCellPND07-28-samps-Mesenchymal-Mesothelial-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ADRA2A NAPRT FHIP1A CDON PLCE1

2.58e-05156995605d95a900e1443d3f6aae163ef2e893d3293203
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

USP29 ADGRV1 TECTA DNAH9 UNC5D

3.10e-05162995bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 PRSS23 ADRA2A CNTNAP2 PLCE1

3.38e-05165995b1bbf5acdfc52bd8c7c7eb356d73b812eb6b908c
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 PRSS23 ADRA2A CNTNAP2 PLCE1

3.38e-0516599528f8297ec7b781149cc7ac2f5e441771083b8ee3
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADRA2A PIK3C2G SPHKAP UTRN FHIP1A

3.79e-051699951c9e54e7b14eb99996590fb93b257cf881a9f184
ToppCellLymphoid-Lymphoid-T_cells_(Cd8+_T_cell)|Lymphoid / shred on cell class and cell subclass (v4)

ADGRG5 EMB EYA2 SSX2IP PLCE1

3.90e-0517099520fd1a312c81c1bf3c5d2d6caf9b578e6b7a4171
ToppCell10x5'-GI_small-bowel-Lymphocytic_NK|GI_small-bowel / Manually curated celltypes from each tissue

ADGRG5 F2RL3 PRSS23 LYST S1PR1

4.35e-0517499509b216f07cffd3ea2149ea95ffb5cd7219b3a98c
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 CNTNAP2 G6PC2 DNAH9 WDR72

4.47e-05175995887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

SMG1 LYST NBAS ZMYM1 PCM1

4.72e-0517799582fdd6185b368f54f03de389427cbe3071d21a99
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMG1 ECM2 DIXDC1 CEP97 PLXNA1

4.85e-05178995c87945146b2734141f07b39d268e0d8086ee0364
ToppCellEndothelial-A-HP_01|World / lung cells shred on cell class, cell subclass, sample id

F2RL3 SOSTDC1 PRSS23 S1PR1 STXBP6

5.12e-051809954c3376169770ee9f9283daae44c17f35e46bfd19
ToppCell10x5'v1-week_12-13-Myeloid_neutrophil-granulo-neutrophil-myelocyte|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TRPM6 WWC3 EMB NAPRT ADAMTS17

5.39e-0518299552eac2f892ea7f26731e0b21c578fd2665a1657a
ToppCelldroplet-Marrow-nan-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMB LYST USP8 STXBP6 PCM1

5.39e-05182995bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS17 G6PC2 UTRN UNC5D PLCE1

5.68e-051849957d41784eac0935e77d6bc701f20c693adf998730
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRV1 SPHKAP ADAMTS17 FHIP1A CDON

5.82e-051859950d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP29 GRM1 SPHKAP CNTNAP2 UNC5D

5.82e-0518599570de48988c1f8e0809afc8092b663aa439d8e528
ToppCellControl-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

F2RL3 SOSTDC1 S1PR1 NEDD4 STXBP6

5.82e-05185995a28187c2fd23564314b35759479ff2ca21f61485
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PRSS23 STXBP6 SSX2IP ADAMTS17 CDON

5.98e-051869954d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCelldroplet-Spleen-nan-3m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 LYST S1PR1 PIK3R4 UTRN

5.98e-0518699526f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP29 GRM1 SPHKAP CNTNAP2 UNC5D

5.98e-05186995d6c8ce2a32c218dcc63d861cc247152430ed3c8c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 PRSS23 PIK3C2G ADAMTS17 FHIP1A

6.13e-05187995f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellControl-Endothelial-VE_Capillary_A|Control / Disease state, Lineage and Cell class

F2RL3 SOSTDC1 S1PR1 NEDD4 STXBP6

6.13e-0518799554d7588172ac145ff5045ad9771636729ca3f0ca
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 PRSS23 PIK3C2G ADAMTS17 FHIP1A

6.44e-05189995e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellControl-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

F2RL3 PRSS23 S1PR1 NEDD4 STXBP6

6.77e-05191995c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMB ADRA2A SPHKAP CNTNAP2 G6PC2

6.94e-051929955b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 PRSS23 ADRA2A CNTNAP2 PLCE1

6.94e-051929958ad6678df89175c5a4a835c8566f1552df3c996e
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 PRSS23 ADRA2A CNTNAP2 PLCE1

6.94e-051929952f5378ea0b2fb2f672a36585d375f675983363a1
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 PRSS23 ADRA2A CNTNAP2 PLCE1

7.11e-05193995f27e2be497745098b5269aa799dd3d5f62d78ba7
ToppCellControl-Fibroblasts-Vascular_smooth_muscle|Control / group, cell type (main and fine annotations)

F2RL3 PRSS23 S1PR1 STXBP6 UNC5D

7.11e-0519399560e44aac8be0430ad35e20eb98b1b700d76a0427
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 PRSS23 ADRA2A CNTNAP2 PLCE1

7.11e-051939954ccf984baebbb13ae916727137ce593fda7514a2
ToppCellLAM-Endothelial|LAM / Condition, Lineage and Cell class

F2RL3 SOSTDC1 PRSS23 S1PR1 STXBP6

7.29e-051949951241e3e75414b619abc9431627619f5c194ec930
ToppCellASK440-Endothelial-Endothelium|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

F2RL3 SOSTDC1 PRSS23 S1PR1 STXBP6

7.47e-05195995304f0dc91bb57e98b0ca31d6bfb3ff9364e4da56
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA2A SPHKAP G6PC2 ATP2B1 PCM1

7.47e-051959953e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA2A SPHKAP G6PC2 ATP2B1 PCM1

7.47e-051959957796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS23 EYA2 STXBP6 PLCE1 WDR72

7.65e-05196995b07db4a53ab9be9aad6fae5e45f9547db829d096
ToppCellCOVID-19-lung-Capillary_Aerocytes|COVID-19 / Disease (COVID-19 only), tissue and cell type

WWC3 F2RL3 S1PR1 NEDD4 STXBP6

7.65e-0519699549cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCellnucseq-Endothelial-Endothelial_Vascular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

F2RL3 PRSS23 S1PR1 NEDD4 STXBP6

7.65e-05196995686533fd3fba8e4df96b9dd1307e870e89db4332
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS23 EYA2 STXBP6 PLCE1 WDR72

7.65e-05196995c366f980cc04abfe1c0c14746c11810c812a42c0
ToppCellCOVID-19-lung-Capillary_Aerocytes|lung / Disease (COVID-19 only), tissue and cell type

F2RL3 SOSTDC1 S1PR1 NEDD4 STXBP6

7.65e-051969954ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCellT_cells-CTLs|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

ADGRG5 PRSS23 LYST S1PR1 ARRB2

7.84e-0519799528117cf300e169182571fbad0de1681a484a435a
ToppCellnucseq-Endothelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

F2RL3 PRSS23 S1PR1 NEDD4 STXBP6

7.84e-05197995ebf9be068eaa658493fa7884fd19f34642922acb
ToppCellPCW_10-12|World / Celltypes from embryonic and fetal-stage human lung

LAPTM4A S1PR1 STXBP6 NAPRT CNTNAP2

7.84e-0519799547fd8b0d596c5db1a722473c8efbb17a6bbe7538
ToppCellParenchyma_COVID-19-Endothelial-TX-Endothelial-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

F2RL3 SOSTDC1 PRSS23 S1PR1 STXBP6

8.22e-05199995edb68a4f622a494f22fd7b25bc40ae0d58456cdb
ToppCellwk_08-11-Mesenchymal-Fibroblast-intermediate_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LAPTM4A SOSTDC1 S1PR1 STXBP6 CNTNAP2

8.22e-05199995f9e3fb974ba8fe1b6d99892577549ef143df9e08
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Endothelial-2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

F2RL3 SOSTDC1 PRSS23 S1PR1 STXBP6

8.22e-05199995448dd5a27d57627468c6b8347f1b6b1005aea004
ToppCelldistal-2-Endothelial-Capillary_Aerocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAPTM4A F2RL3 SOSTDC1 S1PR1 STXBP6

8.22e-05199995bf70c8bfe932bccac5014e55f82019c5148627e7
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Endothelial-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

F2RL3 SOSTDC1 PRSS23 S1PR1 STXBP6

8.22e-0519999545f9c03d2ed2d98d66086fb0251bd24e30c6f775
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-MIR548F2--L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

NEDD4 STXBP6 CNTNAP2 ADAMTS17 PLCE1

8.41e-052009953cbb01039d1e7635ec4dcdf0223587f7ea3c7b34
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-MIR548F2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

NEDD4 STXBP6 CNTNAP2 ADAMTS17 PLCE1

8.41e-0520099597a010a1b6d551239cf6ea5a43319fb413ff180e
ToppCelldistal-2-Endothelial-Capillary|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

F2RL3 PRSS23 S1PR1 PPARGC1B STXBP6

8.41e-052009958daf09d63c2fda6da6e5b66f96e7449ee8b17029
ToppCelldistal-1-Endothelial|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

F2RL3 SOSTDC1 PRSS23 S1PR1 STXBP6

8.41e-052009958f25b27c10e89cf9d0091bd53c24ce63ed7d6222
ToppCelldistal-Endothelial-Capillary|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

F2RL3 PRSS23 S1PR1 PPARGC1B STXBP6

8.41e-052009950ee29b2bd9cd3a1c80e0535017814f752c3eb1fa
ToppCelldistal-Endothelial|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

F2RL3 SOSTDC1 PRSS23 S1PR1 STXBP6

8.41e-05200995b17c9607d4986f8f1facc6b564d4c15c48e58915
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-MIR548F2|Neuronal / cells hierarchy compared to all cells using T-Statistic

NEDD4 STXBP6 CNTNAP2 ADAMTS17 PLCE1

8.41e-052009958ccf2dbbe34b26fbf2bbef1e64b4ae636edd6672
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2-SCUBE1|Neuronal / cells hierarchy compared to all cells using T-Statistic

ADRA2A PIK3C2G SPHKAP UTRN FHIP1A

8.41e-05200995012dd2180f6f596d6e55e864be2e62b53c15edb2
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

F2RL3 SOSTDC1 S1PR1 PPARGC1B STXBP6

8.41e-052009956567683f8f534310fecb44a6721909183fdc15ca
ToppCellParenchymal-10x3prime_v2-Endothelial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

F2RL3 SOSTDC1 PRSS23 S1PR1 STXBP6

8.41e-052009953b07cf1a4dff2e868f52382681a2030c1248caed
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2-SCUBE1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ADRA2A PIK3C2G SPHKAP UTRN FHIP1A

8.41e-0520099506f949c81eecba00203f0716d0c5854724871184
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2|Neuronal / cells hierarchy compared to all cells using T-Statistic

ADRA2A PIK3C2G SPHKAP UTRN FHIP1A

8.41e-05200995d31e26387d879ee30731c497cea6aaf4746e40d9
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

F2RL3 SOSTDC1 S1PR1 NEDD4 STXBP6

8.41e-05200995105c67e4f5eff036013d655c8e8ac577d32dae2e
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2-SCUBE1--L6|Neuronal / cells hierarchy compared to all cells using T-Statistic

ADRA2A PIK3C2G SPHKAP UTRN FHIP1A

8.41e-0520099557e8aea2c2f736ce37940dceb36224552dc33da1
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH4 GRM1 STXBP6 UTRN

1.97e-04129994f83187c0bb06528127b8d2d56674ab1946846951
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EMB TASL ARRB2 AKAP13

2.99e-041449941efa434e577d1f87e02df01667782f414d63bd60
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EMB TASL ARRB2 AKAP13

2.99e-04144994c0c5f254a960ba5e5f1354599d54e77360e6c2ac
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ST7 CLEC20A UNC5D PLCE1

3.15e-041469942ac9b487a7991fdc15444aeb93533030e09825bb
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH4 USP29 GRM1 UTRN

3.24e-0414799450e86860a94be103092c40e39a172eac92372f0d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRM1 STXBP6 CNTNAP2 UTRN

3.96e-041559945c7b68b59244525e3714806c205a57a2daebf423
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH4 USP29 STXBP6 UTRN

4.15e-04157994741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH4 USP29 GRM1 UTRN

4.46e-041609940bfdaf979e6f128cba2928ce16bca4d3deff8ac9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 OR13C4 PIK3C2G ADAMTS17

4.46e-041609948bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

NPTX1 EYA2 STXBP6 PLXNA1

4.46e-0416099458ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 OR13C4 PIK3C2G ADAMTS17

4.46e-041609942d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH4 GRM1 STXBP6 UTRN

4.57e-04161994dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NPTX1 EMB PRSS23 ADRA2A

4.67e-041629944d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPHKAP HERC6 FHIP1A UNC5D

4.78e-041639941e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPHKAP HERC6 FHIP1A UNC5D

4.78e-04163994431221a41d396b09170476179590eaf8a55266d8
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma-3|TCGA-Uterus / Sample_Type by Project: Shred V9

LYST S1PR1 SLC35D1 ADRA2A

4.78e-04163994d64dd39b077105c73e570ccef70f0e74a2c586ac
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG5 C17orf99 TASL ADRA2A

5.01e-041659942477b0f1a0ea26184cf3cc4a9ffcdfa825cbc615
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 SLC35D1 ADRA2A ATP2B1

5.01e-04165994ce79d217df88035457cd58f679e72dd98722ae22
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBCC|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADRA2A PIK3C2G SPHKAP FHIP1A

5.01e-041659947978eefcfc40175e933f7a8b64a5dd1c661dd1ac
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM3 ARRB1 SPHKAP UNC5D

5.12e-04166994ec7bd549bda5f18aca8aebce5ba479a81abbbeda
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADRA2A PIK3C2G SPHKAP FHIP1A

5.12e-04166994a907d39ca5cf023de633fe5f2b28759b7af4eebc
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 SLC35D1 ADRA2A ATP2B1

5.12e-0416699422b31acbbef1936ce19b393cf880c63ea2fa0f1b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

F2RL3 S1PR1 GSK3A ZBTB21

5.12e-04166994c11dcf9705b85ac3da6ae86358f5ffd64ae8327e
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN4|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG5 S1PR1 ARRB2 UTRN

5.24e-0416799410c9fab3573c2948081aac2cec1798e46e59e38a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADRA2A PIK3C2G UTRN FHIP1A

5.24e-04167994a6ff7a3d9b80839c0efa91658836812e868561fa
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH4 NPTX1 SPHKAP CNTNAP2

5.24e-041679943dfec2fcc36caa6e394efae5e540a6fa28759977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH4 NPTX1 SPHKAP CNTNAP2

5.24e-0416799495b3b5ba3414729f0460a26a0deca48de0cbe33e
DiseaseUnipolar Depression

GRM1 FREM3 GSK3A ARRB1 CNTNAP2 DIXDC1

2.07e-04259966C0041696
DiseaseDepressive disorder

GRM1 GSK3A ADRA2A ARRB2 ALG8 DIXDC1

3.71e-04289966C0011581
Diseaseresponse to beta blocker

ADRA2A SPHKAP ATP2B1

4.29e-0445963EFO_0007766
Diseasemaleate measurement, Alpha ketoglutarate measurement, fumarate measurement

EMB PHF14

5.65e-0411962EFO_0010457, EFO_0010480, EFO_0010509
Diseasemiddle temporal gyrus volume measurement

OR13C3 OR13C4

5.65e-0411962EFO_0010316
DiseaseEpilepsy, Cryptogenic

GRM1 ADRA2A CNTNAP2

2.45e-0382963C0086237
DiseaseAwakening Epilepsy

GRM1 ADRA2A CNTNAP2

2.45e-0382963C0751111
DiseaseAura

GRM1 ADRA2A CNTNAP2

2.45e-0382963C0236018
Diseasethalamus volume

NPTX1 ADGRV1 SLC35D1

2.72e-0385963EFO_0006935
Diseasepeptic ulcer disease, Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement, gastroesophageal reflux disease

OR2B2 CNTNAP2

2.76e-0324962EFO_0003948, EFO_0009923, MONDO_0004247

Protein segments in the cluster

PeptideGeneStartEntry
LCISLSSSAYIAVPT

nan

66

Q9N2J8
SSLYSQQVLCSSIPL

SSX2IP

31

Q9Y2D8
QSSPTVSSTCTKVLY

DIXDC1

591

Q155Q3
TPYSSKLLKSCLETV

MASTL

261

Q96GX5
YCTSAISSPLTKSIS

AKAP13

1676

Q12802
SKTILDSCPYLSILA

ADGRV1

5736

Q8WXG9
YLPGLQSCQKSVSST

C8orf89

61

P0DMQ9
SRPQYKTSCGISSLI

BIVM

206

Q86UB2
PERYISSSCVLTSIL

BVES-AS1

51

Q5T3Y7
TVAPSSTFCKVYTLT

ARRB1

261

P49407
SSTFCKVYTITPLLS

ARRB2

266

P32121
TGISVNCAYTSKILP

ATP2B1

516

P20020
TITSPRLAALTYKCT

ADAMTS17

1036

Q8TE56
TSCLIKYNVSTTPYL

CKAP2

586

Q8WWK9
ACSYFTSNALPLKIT

PIK3C2G

891

O75747
LTPGEVYNLATCSTK

NPTX1

386

Q15818
LSLLDACYTSVITPQ

OR9I1

66

Q8NGQ6
ACYTSVITPQILATL

OR9I1

71

Q8NGQ6
ICYTTSSIPSTLVSL

OR13C4

71

Q8NGS5
PTSLCTLLSKGSYQT

NEDD4

281

P46934
VLSCLVAISSLTYLP

LAPTM4A

121

Q15012
SVSIYPSSAEVLKAC

KDM6A

886

O15550
TLSCLLQTLLTGPYS

PCM1

1026

Q15154
LNYTVLIGSTPCTLT

PLXNA1

1186

Q9UIW2
YISVTVPTSCVNSLL

OR14C36

71

Q8NHC7
TSITCHNILSLPKYS

HERC6

981

Q8IVU3
ACYLKISQILTTSPS

NLRP5

881

P59047
KTCLLISYTTNKFPS

CDC42

16

P60953
VPALLKLSCTDTSAY

OR2T27

181

Q8NH04
TPALLKLSCSDVSLY

OR2T34

186

Q8NGX1
TPALLKLSCSDVSLY

OR2T3

186

Q8NH03
ILPLLQLSCTSTYVN

OR8B3

181

Q8NGG8
PLVLKTLACTHSSAY

MROH1

1321

Q8NDA8
INTVRQCTSKLSSYP

DNM2

436

P50570
QSPTCYKQSTKLLGL

NBAS

1251

A2RRP1
QKTSTLPAVLYSCGI

PHF14

716

O94880
LLSPYIGNLSCIIST

PKD1L2

276

Q7Z442
VPAVLKLSCSDTSLY

OR2T10

181

Q8NGZ9
TLLACVNSSSKPLIY

MRGPRG

236

Q86SM5
AYVPSLALSTLNSCV

F2RL3

321

Q96RI0
AICSPLLYSTKMSTQ

OR5P2

121

Q8WZ92
ISPVTSTYCLSPRQK

CCDC181

326

Q5TID7
YSVSAAKLLALTPVC

FHIP1A

431

Q05DH4
LNLIRYTATTKCSPS

FBH1

291

Q8NFZ0
NVTLKSSPDLLTYFC

C17orf99

86

Q6UX52
AIALCSSLLEYTPSS

GSK3A

376

P49840
LVQYLATVCPLTSTL

CEP97

266

Q8IW35
LTILCSSVSSDLAPY

CDON

16

Q4KMG0
YVLSFCKSASIPLTV

G6PC2

321

Q9NQR9
TFSCIRSYSSIVLKP

ECM2

681

O94769
SLFVCKPYSILISVS

LYST

3621

Q99698
SLLCSPCKTTYSGSL

KRTAP13-2

86

Q52LG2
STTKAPCILLYISSF

CNTNAP2

1056

Q9UHC6
KPLISYVGDSTVLTC

EMB

166

Q6PCB8
TPLTDRCYITLTQSL

DNAH9

1846

Q9NYC9
LKRYQSSALTVCSEP

ETV2

206

O00321
FTLIAKPTTTSCYLQ

GRM1

646

Q13255
SALSSCSTVLPLYHK

S1PR1

186

P21453
LSLLDLCYTTSTVPQ

OR2B2

66

Q9GZK3
ICYTSSSVPSTLVSL

OR13C3

101

Q8NGS6
PLLLLSCSSTYVNGV

OR13A1

201

Q8NGR1
ILPLLQLSCTSTYVN

OR8B2

181

Q96RD0
ICYTSASVPTLLVNL

OR2K2

71

Q8NGT1
IPSTEGQSKAYSICL

OR14A16

226

Q8NHC5
SICPSPLSTSTYVLQ

EYA2

191

O00167
LCTVTSQPASGYLEK

FREM3

1106

P0C091
LLSVPDVINCLTTTY

UTRN

2901

P46939
SSLLPSCYSTKDTVV

SPHKAP

426

Q2M3C7
PTTSLSAIIRTPKCY

PLCE1

1741

Q9P212
LNYPFSTSVKLSTGC

PRSS23

146

O95084
TSAIVKPQSSSCSYI

SMG7

136

Q92540
LPVLSTLQLYCSSAL

SMG1

1346

Q96Q15
LQKLLLATSYPTSSS

PPARGC1B

156

Q86YN6
TSLNSADLLKSLCYP

MYH4

391

Q9Y623
KSVLTNYRFPSSLCV

SLC35D1

61

Q9NTN3
ISLPKSATICYTAAL

ST7

361

Q9NRC1
TPYSLQVTLTLVCLA

ADRA2A

41

P08913
LLSLSVKSSVYGPCT

ADGRG5

371

Q8IZF4
VTLLKCLLIPTYHST

ALG8

21

Q9BVK2
TYSPKVYSVNCSSLL

CLEC20A

256

Q6ZU45
STILPSTYQIRITTC

PIK3R4

926

Q99570
THLILTLNKCYATPT

TECTA

1971

O75443
TYICLSVTNKKPTQA

STXBP6

46

Q8NFX7
SVCSSSETPYLLKET

ZBTB21

281

Q9ULJ3
LLTSVLTTALKCSYL

TRAPPC11

491

Q7Z392
CLYQTLDNPLSKLTT

TRPM6

226

Q9BX84
ASRETYLVPSSCKSI

TASL

106

Q9HAI6
AQSCYLLTKTAVSRP

PSTK

131

Q8IV42
VIQTKSTQCLSYPLT

SLC50A1

151

Q9BRV3
STQCLSYPLTIATLL

SLC50A1

156

Q9BRV3
KETIYPHLLCSTSVQ

WDR72

301

Q3MJ13
IPKSLSLSSYCNEST

USP29

531

Q9HBJ7
SICLPLLSVYQLSTN

NUP188

1361

Q5SRE5
TPLLCLVSYASLVAT

NAPRT

136

Q6XQN6
SLERYTPTTTQLSCK

UNC5D

791

Q6UXZ4
SPCSLVNETTLIKYS

RALGAPB

921

Q86X10
TKYISDGQCTSISPL

SOSTDC1

81

Q6X4U4
NYPLSAALTCAKLTT

EMG1

221

Q92979
VNVSLQCLTYTLPLS

USP17L7

91

P0C7H9
SNIPCLSKLLYIALS

ZMYM1

1061

Q5SVZ6
SFSTLPRLKTYLCNT

ZMYM1

1086

Q5SVZ6
YLSLPLASTSKCTLQ

USP8

951

P40818
LTLKSLQLYVCSVTP

WWC3

681

Q9ULE0
CYETLSKTNPSVSSL

GEMIN4

1011

P57678