Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity	NANOGP8 NANOG	4.79e-05	4	57	2	GO:0001010
GeneOntologyMolecularFunction	extracellular matrix constituent, lubricant activity	MUC3A MUC4	4.79e-05	4	57	2	GO:0030197
GeneOntologyMolecularFunction	3-hydroxyacyl-CoA dehydratase activity	EHHADH HACD2	2.22e-04	8	57	2	GO:0018812
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA5 ATP2B2 ATP2B3 ABCA8	2.66e-04	109	57	4	GO:0042626
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	GABRG2 NPBWR2 OR10A7 MCHR2 OR1D5 NTSR2 GRIA1 OR7G3 OR1D4 ADGRG4 FCRL6 MUSK	3.64e-04	1353	57	12	GO:0004888
GeneOntologyMolecularFunction	PDZ domain binding	GRIA1 ATP2B2 ATP2B3 MUSK	4.21e-04	123	57	4	GO:0030165
GeneOntologyMolecularFunction	P-type calcium transporter activity	ATP2B2 ATP2B3	4.33e-04	11	57	2	GO:0005388
GeneOntologyMolecularFunction	enoyl-CoA hydratase activity	EHHADH HACD2	5.19e-04	12	57	2	GO:0004300
GeneOntologyBiologicalProcess	negative regulation of endodermal cell fate specification	NANOGP8 NANOG	4.33e-05	4	56	2	GO:0042664
GeneOntologyBiologicalProcess	regulation of cardiac conduction	ATP2B2 ATP2B3 TBX5	6.59e-05	29	56	3	GO:1903779
GeneOntologyBiologicalProcess	regulation of endodermal cell fate specification	NANOGP8 NANOG	7.20e-05	5	56	2	GO:0042663
GeneOntologyBiologicalProcess	negative regulation of endodermal cell differentiation	NANOGP8 NANOG	1.08e-04	6	56	2	GO:1903225
GeneOntologyBiologicalProcess	cell junction assembly	GABRG2 MAP1B LRRTM2 GRIA1 SLITRK6 MUSK CDH12 TBX5	1.41e-04	569	56	8	GO:0034329
GeneOntologyBiologicalProcess	synapse assembly	GABRG2 MAP1B LRRTM2 GRIA1 SLITRK6 MUSK	1.83e-04	308	56	6	GO:0007416
GeneOntologyBiologicalProcess	negative regulation of cell fate specification	NANOGP8 NANOG	2.01e-04	8	56	2	GO:0009996
GeneOntologyCellularComponent	ATF4-CREB1 transcription factor complex	ATF1 CREM	4.37e-05	4	57	2	GO:1990589
GeneOntologyCellularComponent	excitatory synapse	LRRTM2 GRIA1 ATP2B2 ATP2B3	2.08e-04	107	57	4	GO:0060076
GeneOntologyCellularComponent	dendrite membrane	GABRG2 GRIA1 ATP2B2	4.81e-04	56	57	3	GO:0032590
GeneOntologyCellularComponent	GABA-ergic synapse	GABRG2 LRRTM2 ATP2B2 ATP2B3	1.04e-03	164	57	4	GO:0098982
GeneOntologyCellularComponent	dendritic spine membrane	GRIA1 ATP2B2	1.09e-03	18	57	2	GO:0032591
Domain	SEA	IMPG1 MUC16 MUC3A	8.60e-06	14	55	3	SM00200
Domain	KID	ATF1 CREM	2.55e-05	3	55	2	PS50953
Domain	Coactivator_CBP_pKID	ATF1 CREM	2.55e-05	3	55	2	IPR003102
Domain	pKID	ATF1 CREM	2.55e-05	3	55	2	PF02173
Domain	SEA	IMPG1 MUC16 MUC3A	4.10e-05	23	55	3	PS50024
Domain	SEA_dom	IMPG1 MUC16 MUC3A	4.10e-05	23	55	3	IPR000082
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B3	5.09e-05	4	55	2	IPR022141
Domain	Leuzip_CREB	ATF1 CREM	5.09e-05	4	55	2	IPR001630
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B3	5.09e-05	4	55	2	PF12424
Domain	P-type_ATPase_IIB	ATP2B2 ATP2B3	5.09e-05	4	55	2	IPR006408
Domain	Hydrolase_3	ATP2B2 ATP2B3	3.77e-04	10	55	2	PF08282
Domain	ABC_A	ABCA5 ABCA8	5.51e-04	12	55	2	IPR026082
Domain	EGF-like_dom	SCUBE1 IMPG1 C1S MUC3A MUC4	8.17e-04	249	55	5	IPR000742
Domain	-	IMPG1 MUC16	8.72e-04	15	55	2	3.30.70.960
Domain	-	ATP2B2 ATP2B3	9.95e-04	16	55	2	1.20.1110.10
Domain	ATPase_P-typ_TM_dom	ATP2B2 ATP2B3	9.95e-04	16	55	2	IPR023298
Domain	ATPase_P-typ_cation-transptr_C	ATP2B2 ATP2B3	1.13e-03	17	55	2	IPR006068
Domain	Cation_ATPase_C	ATP2B2 ATP2B3	1.13e-03	17	55	2	PF00689
Domain	Cation_ATPase_N	ATP2B2 ATP2B3	1.26e-03	18	55	2	PF00690
Domain	Cation_ATPase_N	ATP2B2 ATP2B3	1.26e-03	18	55	2	SM00831
Domain	ATPase_P-typ_cation-transptr_N	ATP2B2 ATP2B3	1.41e-03	19	55	2	IPR004014
Domain	SEA	IMPG1 MUC16	1.89e-03	22	55	2	PF01390
Domain	7tm_1	NPBWR2 OR10A7 MCHR2 OR1D5 NTSR2 OR7G3 OR1D4	3.57e-03	677	55	7	PF00001
Domain	G_PROTEIN_RECEP_F1_1	NPBWR2 OR10A7 MCHR2 OR1D5 NTSR2 OR7G3 OR1D4	3.81e-03	685	55	7	PS00237
Domain	G_PROTEIN_RECEP_F1_2	NPBWR2 OR10A7 MCHR2 OR1D5 NTSR2 OR7G3 OR1D4	3.99e-03	691	55	7	PS50262
Domain	GPCR_Rhodpsn	NPBWR2 OR10A7 MCHR2 OR1D5 NTSR2 OR7G3 OR1D4	4.02e-03	692	55	7	IPR000276
Domain	bZIP_1	ATF1 CREM	4.50e-03	34	55	2	PF00170
Domain	ATPase_P-typ_cyto_domN	ATP2B2 ATP2B3	4.76e-03	35	55	2	IPR023299
Domain	P_typ_ATPase	ATP2B2 ATP2B3	5.03e-03	36	55	2	IPR001757
Domain	ATPase_P-typ_P_site	ATP2B2 ATP2B3	5.03e-03	36	55	2	IPR018303
Domain	ATPASE_E1_E2	ATP2B2 ATP2B3	5.03e-03	36	55	2	PS00154
Domain	EGF_3	SCUBE1 C1S MUC3A MUC4	5.04e-03	235	55	4	PS50026
Domain	ATPase_P-typ_transduc_dom_A	ATP2B2 ATP2B3	5.31e-03	37	55	2	IPR008250
Domain	E1-E2_ATPase	ATP2B2 ATP2B3	5.31e-03	37	55	2	PF00122
Domain	TF_DNA-bd	ATF1 CREM	5.31e-03	37	55	2	IPR008917
Domain	EGF_1	SCUBE1 C1S MUC3A MUC4	6.71e-03	255	55	4	PS00022
Domain	EGF-like_CS	SCUBE1 C1S MUC3A MUC4	7.27e-03	261	55	4	IPR013032
Domain	EGF_2	SCUBE1 C1S MUC3A MUC4	7.67e-03	265	55	4	PS01186
Domain	AAA+_ATPase	ABCA5 GPN1 ABCA8	8.79e-03	144	55	3	IPR003593
Domain	AAA	ABCA5 GPN1 ABCA8	8.79e-03	144	55	3	SM00382
Domain	ABC_tran	ABCA5 ABCA8	8.81e-03	48	55	2	PF00005
Domain	ABC_TRANSPORTER_2	ABCA5 ABCA8	8.81e-03	48	55	2	PS50893
Domain	ABC_TRANSPORTER_1	ABCA5 ABCA8	9.16e-03	49	55	2	PS00211
Domain	CUB	SCUBE1 C1S	9.16e-03	49	55	2	PF00431
Domain	CUB	SCUBE1 C1S	9.53e-03	50	55	2	SM00042
Domain	ABC_transporter-like	ABCA5 ABCA8	9.53e-03	50	55	2	IPR003439
Domain	BRLZ	ATF1 CREM	1.03e-02	52	55	2	SM00338
Domain	-	SCUBE1 C1S	1.03e-02	52	55	2	2.60.120.290
Domain	CUB	SCUBE1 C1S	1.07e-02	53	55	2	PS01180
Domain	BZIP	ATF1 CREM	1.07e-02	53	55	2	PS50217
Domain	BZIP_BASIC	ATF1 CREM	1.07e-02	53	55	2	PS00036
Domain	bZIP	ATF1 CREM	1.10e-02	54	55	2	IPR004827
Pathway	REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC	MUC16 MUC3A MUC4	1.77e-05	16	46	3	M27410
Pathway	REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS	MUC16 MUC3A MUC4	2.14e-05	17	46	3	M27412
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC16 MUC3A MUC4	5.50e-05	23	46	3	M556
Pathway	REACTOME_DECTIN_2_FAMILY	MUC16 MUC3A MUC4	8.02e-05	26	46	3	M27483
Pubmed	TET1 Interacts Directly with NANOG via Independent Domains Containing Hydrophobic and Aromatic Residues.	NANOGP8 NANOG TET1	1.67e-08	4	57	3	33058869
Pubmed	Endogenous epitope-tagging of Tet1, Tet2 and Tet3 identifies TET2 as a naïve pluripotency marker.	NANOGP8 NANOG TET1	4.16e-08	5	57	3	31582397
Pubmed	Nanog, Oct4 and Tet1 interplay in establishing pluripotency.	NANOGP8 NANOG TET1	8.32e-08	6	57	3	27146218
Pubmed	Identification of Oct4-activating compounds that enhance reprogramming efficiency.	NANOGP8 NANOG TET1	1.45e-07	7	57	3	23213213
Pubmed	Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis.	NANOGP8 NANOG TET1	2.32e-07	8	57	3	26199412
Pubmed	ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1.	NANOGP8 NANOG TET1	3.48e-07	9	57	3	38237590
Pubmed	Localization of two genes encoding plasma membrane Ca2+ ATPases isoforms 2 (ATP2B2) and 3 (ATP2B3) to human chromosomes 3p26-->p25 and Xq28, respectively.	ATP2B2 ATP2B3	2.64e-06	2	57	2	8187550
Pubmed	Functional evidence that the self-renewal gene NANOG regulates human tumor development.	NANOGP8 NANOG	2.64e-06	2	57	2	19415763
Pubmed	Nanog1 in NTERA-2 and recombinant NanogP8 from somatic cancer cells adopt multiple protein conformations and migrate at multiple M.W species.	NANOGP8 NANOG	2.64e-06	2	57	2	24598770
Pubmed	Differential expression of nanog1 and nanogp8 in colon cancer cells.	NANOGP8 NANOG	2.64e-06	2	57	2	22079639
Pubmed	Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.	MUC16 MUC4	2.64e-06	2	57	2	23544943
Pubmed	Expression of NANOG and NANOGP8 in a variety of undifferentiated and differentiated human cells.	NANOGP8 NANOG	2.64e-06	2	57	2	21136380
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC16 MUC3A MUC4	3.35e-06	18	57	3	18834073
Pubmed	Oct4 Methylation-Mediated Silencing As an Epigenetic Barrier Preventing Müller Glia Dedifferentiation in a Murine Model of Retinal Injury.	NANOGP8 NANOG TET1	3.35e-06	18	57	3	27895551
Pubmed	Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.	NANOGP8 NANOG	7.91e-06	3	57	2	19447925
Pubmed	The pluripotency factor NANOG controls primitive hematopoiesis and directly regulates Tal1.	NANOGP8 NANOG	7.91e-06	3	57	2	30814124
Pubmed	The molecular logic of Nanog-induced self-renewal in mouse embryonic stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	30846691
Pubmed	Generation of germline-competent induced pluripotent stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	17554338
Pubmed	Multiple phases in regulation of Nanog expression during pre-implantation development.	NANOGP8 NANOG	7.91e-06	3	57	2	26660234
Pubmed	Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.	MUC16 MUC4	7.91e-06	3	57	2	23053434
Pubmed	Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog.	NANOGP8 NANOG	7.91e-06	3	57	2	18177668
Pubmed	Expression of Nanog gene promotes NIH3T3 cell proliferation.	NANOGP8 NANOG	7.91e-06	3	57	2	16259959
Pubmed	A novel NK-type homeobox gene, ENK (early embryo specific NK), preferentially expressed in embryonic stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	12609610
Pubmed	Cutting edge: Hypoxia-induced Nanog favors the intratumoral infiltration of regulatory T cells and macrophages via direct regulation of TGF-β1.	NANOGP8 NANOG	7.91e-06	3	57	2	24227785
Pubmed	Nanog co-regulated by Nodal/Smad2 and Oct4 is required for pluripotency in developing mouse epiblast.	NANOGP8 NANOG	7.91e-06	3	57	2	24929238
Pubmed	Nanog and transcriptional networks in embryonic stem cell pluripotency.	NANOGP8 NANOG	7.91e-06	3	57	2	17211451
Pubmed	The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis.	NANOGP8 NANOG	7.91e-06	3	57	2	23770853
Pubmed	The stem cell pluripotency factor NANOG activates transcription with two unusually potent subdomains at its C terminus.	NANOGP8 NANOG	7.91e-06	3	57	2	15502159
Pubmed	Nanog variability and pluripotency regulation of embryonic stem cells--insights from a mathematical model analysis.	NANOGP8 NANOG	7.91e-06	3	57	2	20574542
Pubmed	lincRNAs act in the circuitry controlling pluripotency and differentiation.	NANOGP8 NANOG	7.91e-06	3	57	2	21874018
Pubmed	Cell signalling regulates dynamics of Nanog distribution in embryonic stem cell populations.	NANOGP8 NANOG	7.91e-06	3	57	2	23054952
Pubmed	Nanog-independent reprogramming to iPSCs with canonical factors.	NANOGP8 NANOG	7.91e-06	3	57	2	24527385
Pubmed	Aromatic residues in the C-terminal domain 2 are required for Nanog to mediate LIF-independent self-renewal of mouse embryonic stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	18086680
Pubmed	Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.	MUC16 MUC4	7.91e-06	3	57	2	30236127
Pubmed	Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	17204467
Pubmed	CrxOS maintains the self-renewal capacity of murine embryonic stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	19800316
Pubmed	Chromatin decondensation and nuclear softening accompany Nanog downregulation in embryonic stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	23200040
Pubmed	Selenium Augments microRNA Directed Reprogramming of Fibroblasts to Cardiomyocytes via Nanog.	NANOGP8 NANOG	7.91e-06	3	57	2	26975336
Pubmed	Nanog suppresses cell migration by downregulating thymosin β4 and Rnd3.	NANOGP8 NANOG	7.91e-06	3	57	2	23329853
Pubmed	NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers.	NANOGP8 NANOG	7.91e-06	3	57	2	26751055
Pubmed	Epigenetic regulation of Nanog gene in embryonic stem and trophoblast stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	17352742
Pubmed	OCT4/SOX2-independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells.	NANOGP8 NANOG	7.91e-06	3	57	2	23178592
Pubmed	Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency.	NANOGP8 NANOG	7.91e-06	3	57	2	25005472
Pubmed	Roles of the Nanog protein in murine F9 embryonal carcinoma cells and their endoderm-differentiated counterparts.	NANOGP8 NANOG	7.91e-06	3	57	2	16773043
Pubmed	Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.	NANOGP8 NANOG	7.91e-06	3	57	2	23665121
Pubmed	Ectopic overexpression of Nanog induces tumorigenesis in non-tumorous fibroblasts.	NANOGP8 NANOG	7.91e-06	3	57	2	26733157
Pubmed	mNanog possesses dorsal mesoderm-inducing ability by modulating both BMP and Activin/nodal signaling in Xenopus ectodermal cells.	NANOGP8 NANOG	7.91e-06	3	57	2	23071603
Pubmed	Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features.	NANOGP8 NANOG	7.91e-06	3	57	2	16501172
Pubmed	Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone.	MUC16 MUC4	7.91e-06	3	57	2	17592322
Pubmed	Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	19582141
Pubmed	NANOG induction of fetal liver kinase-1 (FLK1) transcription regulates endothelial cell proliferation and angiogenesis.	NANOGP8 NANOG	7.91e-06	3	57	2	21119109
Pubmed	Pluripotency factor NANOG promotes germ cell maintenance in vitro without triggering dedifferentiation of spermatogonial stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	32145514
Pubmed	Nanog is the gateway to the pluripotent ground state.	NANOGP8 NANOG	7.91e-06	3	57	2	19703398
Pubmed	Nanog safeguards pluripotency and mediates germline development.	NANOGP8 NANOG	7.91e-06	3	57	2	18097409
Pubmed	Nanog Fluctuations in Embryonic Stem Cells Highlight the Problem of Measurement in Cell Biology.	NANOGP8 NANOG	7.91e-06	3	57	2	28636920
Pubmed	Heterogeneities in Nanog Expression Drive Stable Commitment to Pluripotency in the Mouse Blastocyst.	NANOGP8 NANOG	7.91e-06	3	57	2	25753417
Pubmed	A distinct expression pattern in mammalian testes indicates a conserved role for NANOG in spermatogenesis.	NANOGP8 NANOG	7.91e-06	3	57	2	20539761
Pubmed	Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes.	NANOGP8 NANOG	7.91e-06	3	57	2	18584034
Pubmed	Alternative splicing produces Nanog protein variants with different capacities for self-renewal and pluripotency in embryonic stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	21969378
Pubmed	Activating transcription factor 1 and cyclic AMP response element modulator can modulate the activity of the immunoglobulin kappa 3' enhancer.	ATF1 CREM	7.91e-06	3	57	2	7730336
Pubmed	The phosphoinositide-3-kinase/Akt pathway mediates the transient increase in Nanog expression during differentiation of F9 cells.	NANOGP8 NANOG	7.91e-06	3	57	2	20661723
Pubmed	NANOG restores the impaired myogenic differentiation potential of skeletal myoblasts after multiple population doublings.	NANOGP8 NANOG	7.91e-06	3	57	2	29245050
Pubmed	Cancer vaccination drives Nanog-dependent evolution of tumor cells toward an immune-resistant and stem-like phenotype.	NANOGP8 NANOG	7.91e-06	3	57	2	22337995
Pubmed	The pluripotency rheostat Nanog functions as a dimer.	NANOGP8 NANOG	7.91e-06	3	57	2	18290762
Pubmed	Reprogramming of mouse fibroblasts into induced pluripotent stem cells with Nanog.	NANOGP8 NANOG	7.91e-06	3	57	2	23333380
Pubmed	Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation.	NANOGP8 NANOG	7.91e-06	3	57	2	15494369
Pubmed	Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	25825768
Pubmed	Epithelial cell senescence induces pulmonary fibrosis through Nanog-mediated fibroblast activation.	NANOGP8 NANOG	7.91e-06	3	57	2	31891567
Pubmed	Identification of two distinct transactivation domains in the pluripotency sustaining factor nanog.	NANOGP8 NANOG	7.91e-06	3	57	2	14728807
Pubmed	Isolation and characterization of the murine Nanog gene promoter.	NANOGP8 NANOG	7.91e-06	3	57	2	15916719
Pubmed	Nanog retrotransposed genes with functionally conserved open reading frames.	NANOGP8 NANOG	7.91e-06	3	57	2	16845474
Pubmed	DNA cytosine methylation in the bovine leukemia virus promoter is associated with latency in a lymphoma-derived B-cell line: potential involvement of direct inhibition of cAMP-responsive element (CRE)-binding protein/CRE modulator/activation transcription factor binding.	ATF1 CREM	7.91e-06	3	57	2	20413592
Pubmed	Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions.	NANOGP8 NANOG	7.91e-06	3	57	2	21194951
Pubmed	Identification and regulation of a stage-specific stem cell niche enriched by Nanog-positive spermatogonial stem cells in the mouse testis.	NANOGP8 NANOG	7.91e-06	3	57	2	22388986
Pubmed	NANOG changes in mouse kidneys with age.	NANOGP8 NANOG	7.91e-06	3	57	2	16313224
Pubmed	Nanog promotes transfer of pluripotency after cell fusion.	NANOGP8 NANOG	7.91e-06	3	57	2	16791199
Pubmed	Effect of Nanog overexpression on the metastatic potential of a mouse melanoma cell line B16-BL6.	NANOGP8 NANOG	7.91e-06	3	57	2	33665763
Pubmed	Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	18024963
Pubmed	The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	27125671
Pubmed	Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain.	NANOGP8 NANOG	7.91e-06	3	57	2	22028025
Pubmed	Context-Dependent Functions of NANOG Phosphorylation in Pluripotency and Reprogramming.	NANOGP8 NANOG	7.91e-06	3	57	2	28457890
Pubmed	Requirement of Nanog dimerization for stem cell self-renewal and pluripotency.	NANOGP8 NANOG	7.91e-06	3	57	2	18436640
Pubmed	Stochastic promoter activation affects Nanog expression variability in mouse embryonic stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	25410303
Pubmed	Genome editing demonstrates that the -5 kb Nanog enhancer regulates Nanog expression by modulating RNAPII initiation and/or recruitment.	NANOGP8 NANOG	7.91e-06	3	57	2	33334884
Pubmed	NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation.	NANOGP8 NANOG	7.91e-06	3	57	2	21499299
Pubmed	Phosphorylation of NANOG by casein kinase I regulates embryonic stem cell self-renewal.	NANOGP8 NANOG	7.91e-06	3	57	2	33107035
Pubmed	Forced expression of Nanog in hematopoietic stem cells results in a gammadeltaT-cell disorder.	NANOGP8 NANOG	7.91e-06	3	57	2	17360937
Pubmed	H3K9 tri-methylation at Nanog times differentiation commitment and enables the acquisition of primitive endoderm fate.	NANOGP8 NANOG	7.91e-06	3	57	2	35976266
Pubmed	Nanog dynamics in single embryonic stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	26760119
Pubmed	Nanog is dispensable for the generation of induced pluripotent stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	24461999
Pubmed	Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.	MUC16 MUC4	7.91e-06	3	57	2	35879412
Pubmed	Locating and Characterizing a Transgene Integration Site by Nanopore Sequencing.	NANOGP8 NANOG	7.91e-06	3	57	2	30837263
Pubmed	Nanog induces hyperplasia without initiating tumors.	NANOGP8 NANOG	7.91e-06	3	57	2	25173648
Pubmed	Distinct Contributions of Tryptophan Residues within the Dimerization Domain to Nanog Function.	NANOGP8 NANOG	7.91e-06	3	57	2	27939294
Pubmed	Cell-permeant recombinant Nanog protein promotes pluripotency by inhibiting endodermal specification.	NANOGP8 NANOG	7.91e-06	3	57	2	24681518
Pubmed	Transient Activation of Mitoflashes Modulates Nanog at the Early Phase of Somatic Cell Reprogramming.	NANOGP8 NANOG	7.91e-06	3	57	2	26549484
Pubmed	Identification of genes regulated by nanog which is involved in ES cells pluripotency and early differentiation.	NANOGP8 NANOG	7.91e-06	3	57	2	18442017
Pubmed	Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).	MUC16 MUC4	7.91e-06	3	57	2	27483328
Pubmed	MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.	MUC16 MUC4	7.91e-06	3	57	2	24204560
Pubmed	Mapping dynamic histone acetylation patterns to gene expression in nanog-depleted murine embryonic stem cells.	NANOGP8 NANOG	7.91e-06	3	57	2	21187909
Cytoband	20q11.21	DUSP15 BPIFB2	1.58e-03	47	57	2	20q11.21
GeneFamily	CD molecules\|Mucins	MUC16 MUC3A MUC4	1.51e-05	21	42	3	648
GeneFamily	ATPases Ca2+ transporting	ATP2B2 ATP2B3	1.88e-04	9	42	2	1209
GeneFamily	ATP binding cassette subfamily A	ABCA5 ABCA8	4.71e-04	14	42	2	805
GeneFamily	Olfactory receptors, family 1	OR1D5 OR1D4	3.89e-03	40	42	2	147
GeneFamily	Basic leucine zipper proteins	ATF1 CREM	5.78e-03	49	42	2	506
GeneFamily	NKL subclass homeoboxes and pseudogenes	NANOGP8 NANOG	1.06e-02	67	42	2	519
CoexpressionAtlas	FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#4	IGSF10 NANOG INSIG2 GRIA1 C1S DUSP15 SLITRK6 MUC4	3.01e-05	529	50	8	Facebase_RNAseq_e10.5_Olfactory Pit_2500_K4
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	A2M IGSF10 GRIA1 C1S ABCA8 MUSK	1.66e-07	195	56	6	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	A2M IGSF10 GRIA1 ABCA8 MUSK TBX5	1.66e-07	195	56	6	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	A2M IGSF10 GRIA1 C1S ABCA8 MUSK	1.66e-07	195	56	6	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	A2M IGSF10 GRIA1 C1S ABCA8 MUSK	1.71e-07	196	56	6	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	A2M IGSF10 GRIA1 C1S ABCA8 MUSK	1.71e-07	196	56	6	cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	A2M IGSF10 GRIA1 C1S ABCA8 MUSK	1.71e-07	196	56	6	9737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	A2M GRIA1 C1S ABCA8 MUSK TBX5	1.71e-07	196	56	6	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	A2M IGSF10 GRIA1 C1S ABCA8 MUSK	1.77e-07	197	56	6	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	A2M IGSF10 GRIA1 C1S ABCA8 MUSK	1.77e-07	197	56	6	13896ec65ccda0b928c91d41112dc01b480036b7
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	A2M GRIA1 C1S ABCA8 MUSK TBX5	1.82e-07	198	56	6	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	A2M IGSF10 GRIA1 C1S ABCA8 MUSK	1.82e-07	198	56	6	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	distal-mesenchymal-Alveolar_Fibroblast-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	A2M IGSF10 GRIA1 C1S ABCA8 MUSK	1.88e-07	199	56	6	28c1722deef3b8347371c7359be7c64b95780de3
ToppCell	343B-Fibroblasts-Fibroblast-G\|343B / Donor, Lineage, Cell class and subclass (all cells)	A2M IGSF10 GRIA1 C1S ABCA8 TBX5	1.88e-07	199	56	6	f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell	343B-Fibroblasts-Fibroblast-G-\|343B / Donor, Lineage, Cell class and subclass (all cells)	A2M IGSF10 GRIA1 C1S ABCA8 TBX5	1.88e-07	199	56	6	9c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCell	distal-2-mesenchymal-Alveolar_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	A2M IGSF10 GRIA1 C1S ABCA8 MUSK	1.93e-07	200	56	6	12b705dabec1b3752a488a891eda1a5123fcdc41
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	A2M GRIA1 C1S ABCA8 ADGRG4 TBX5	1.93e-07	200	56	6	3dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	A2M IGSF10 GRIA1 C1S ABCA8 MUSK	1.93e-07	200	56	6	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	A2M IGSF10 GRIA1 C1S ABCA8 MUSK	1.93e-07	200	56	6	a510deaada669e690329183e18df02870bd204b3
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	A2M IGSF10 GRIA1 C1S ABCA8 MUSK	1.93e-07	200	56	6	dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	A2M PTPRQ GRIA1 C1S TBX5	2.89e-06	177	56	5	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	A2M PTPRQ GRIA1 C1S TBX5	2.89e-06	177	56	5	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	IGSF10 GRIA1 C1S ABCA8 TBX5	3.05e-06	179	56	5	10fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCell	Ciliated_cells-A-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	MAP1B MUC16 BPIFB2 TUBA4B MUC4	3.14e-06	180	56	5	d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	A2M IGSF10 GRIA1 ABCA8 MUSK	3.22e-06	181	56	5	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	A2M MAP1B SVIL LRRTM2 C1S	3.40e-06	183	56	5	af8d86f15a549064530d94bd47081daf59d58ecd
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	A2M SCUBE1 MAP1B C1S SLITRK6	3.68e-06	186	56	5	d3509a579871ba6a8c4edd6137b28f271c9dbe70
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	A2M IGSF10 C1S ABCA8 MUSK	3.68e-06	186	56	5	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUP62CL GRIA1 C1S MUSK TBX5	3.78e-06	187	56	5	976b74d081b7fba8620768613cc26f9262cd7b16
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	A2M GRIA1 ABCA8 MUSK TBX5	3.78e-06	187	56	5	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	A2M GRIA1 ABCA8 MUSK TBX5	4.09e-06	190	56	5	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	ASK440-Mesenchymal-Fibroblast\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	A2M IGSF10 GRIA1 C1S ABCA8	4.19e-06	191	56	5	387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCell	ASK440-Mesenchymal\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	A2M IGSF10 GRIA1 C1S ABCA8	4.19e-06	191	56	5	f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	A2M GRIA1 ABCA8 MUSK TBX5	4.19e-06	191	56	5	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	A2M GRIA1 ABCA8 MUSK TBX5	4.30e-06	192	56	5	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGSF10 GRIA1 C1S ABCA8 TBX5	4.30e-06	192	56	5	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	A2M IGSF10 MAP1B C1S ABCA8	4.30e-06	192	56	5	c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	A2M MAP1B SVIL LRRTM2 C1S	4.41e-06	193	56	5	146e8c148478ab61b1c1dbaf1ee98a8cd4a0ff8a
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	A2M GRIA1 C1S ABCA8 TBX5	4.41e-06	193	56	5	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGSF10 GRIA1 C1S ABCA8 TBX5	4.52e-06	194	56	5	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	Control-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	A2M GRIA1 C1S ABCA8 TBX5	4.52e-06	194	56	5	3c2266772c5b56e8e02a461e5193e29588028ee9
ToppCell	(5)_Fibroblast-C_(Myofibroblast)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	A2M IGSF10 C1S ABCA8 TBX5	4.52e-06	194	56	5	29a72e565c19407bbd198cfbc2a78106fe830d05
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGSF10 GRIA1 C1S ABCA8 TBX5	4.52e-06	194	56	5	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	Control-Stromal-Myofibroblast\|Control / Disease state, Lineage and Cell class	A2M GRIA1 C1S ABCA8 TBX5	4.64e-06	195	56	5	ffcf76cd72e43d8cf1058a49c76e0956065038bc
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	A2M GRIA1 ABCA8 MUSK TBX5	4.64e-06	195	56	5	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SCUBE1 MAP1B SVIL SLITRK6 TBX5	4.64e-06	195	56	5	4dba732c8d8ecf0ed9ece1814dc4060402199ed9
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRG2 MAP1B ABCA5 GRIA1 ATP2B2	4.75e-06	196	56	5	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	A2M IGSF10 GRIA1 ABCA8 TBX5	4.75e-06	196	56	5	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	IPF-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	A2M MAP1B C1S ABCA8 TBX5	4.75e-06	196	56	5	7fc9894ceb79dab9f0495acc84e2d6d0d1c69bb7
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	A2M MAP1B C1S ATP2B3 TBX5	4.87e-06	197	56	5	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	A2M GRIA1 ABCA8 ADGRG4 TBX5	4.87e-06	197	56	5	0dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	A2M SCUBE1 MAP1B C1S ABCA8	4.87e-06	197	56	5	2cb1f557ce1400398975de94638126b4522567f3
ToppCell	COPD-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	A2M C1S ABCA8 MUSK TBX5	4.87e-06	197	56	5	d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCell	normal_Lung-Fibroblasts-COL13A1+_matrix_FBs\|normal_Lung / Location, Cell class and cell subclass	A2M IGSF10 GRIA1 C1S ABCA8	4.87e-06	197	56	5	6c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRG2 MAP1B ABCA5 GRIA1 ATP2B2	5.00e-06	198	56	5	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|367C / Donor, Lineage, Cell class and subclass (all cells)	A2M IGSF10 C1S ABCA8 TBX5	5.00e-06	198	56	5	a9afedbc0556faf4a46f7bf28f4a9adb3bc859d8
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRG2 MAP1B ABCA5 GRIA1 ATP2B2	5.00e-06	198	56	5	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRG2 MAP1B ABCA5 GRIA1 ATP2B2	5.00e-06	198	56	5	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	A2M GRIA1 C1S ABCA8 TBX5	5.00e-06	198	56	5	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	A2M IGSF10 C1S ABCA8 TBX5	5.00e-06	198	56	5	7b5350768f306ec528e271d2ac4470bf668ec6f0
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRG2 MAP1B ABCA5 GRIA1 ATP2B2	5.00e-06	198	56	5	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	proximal-mesenchymal-Alveolar_Fibroblast\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	A2M IGSF10 GRIA1 C1S ABCA8	5.12e-06	199	56	5	7f4840ae6a888380feca722543e5e52783f3e35d
ToppCell	distal-mesenchymal-Alveolar_Fibroblast-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	A2M IGSF10 GRIA1 C1S ABCA8	5.12e-06	199	56	5	fb23ecce41e31e2cc01814e3c0add756f489561f
ToppCell	ILEUM-inflamed-(8)_Fibroblasts\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	A2M C1S SLITRK6 ABCA8 MUSK	5.12e-06	199	56	5	3a3e2bb21cd0293622b1a975263e918d9ba24265
ToppCell	proximal-3-mesenchymal-Alveolar_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	A2M IGSF10 GRIA1 C1S ABCA8	5.12e-06	199	56	5	301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	IGSF10 C1S SLITRK6 ABCA8 TBX5	5.12e-06	199	56	5	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	A2M IGSF10 GRIA1 C1S ABCA8	5.12e-06	199	56	5	66a79732caf2f04c09b4d9832377aa01ca477677
ToppCell	proximal-mesenchymal-Alveolar_Fibroblast-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	A2M IGSF10 GRIA1 C1S ABCA8	5.12e-06	199	56	5	9a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCell	distal-mesenchymal-Alveolar_Fibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	A2M IGSF10 GRIA1 C1S ABCA8	5.12e-06	199	56	5	655d07cf9a2fd9b945a2ed4f824cba0297de72a8
ToppCell	(5)_Fibroblast-G\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	A2M IGSF10 GRIA1 C1S ABCA8	5.12e-06	199	56	5	b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCell	cellseq-Mesenchymal-Fibroblastic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	A2M IGSF10 GRIA1 C1S ABCA8	5.25e-06	200	56	5	8978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCell	cellseq-Mesenchymal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	A2M MAP1B C1S ABCA8 TBX5	5.25e-06	200	56	5	238285fc372ce2e5e4341fc3084a3a833bf4a0a6
ToppCell	medial-mesenchymal-Alveolar_Fibroblast-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	A2M IGSF10 GRIA1 C1S ABCA8	5.25e-06	200	56	5	5c0716bf375c8158f7dc2c82bf5eaf37af594dd0
ToppCell	Parenchyma_Control_(B.)-Stromal-TX\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	A2M IGSF10 MAP1B C1S ABCA8	5.25e-06	200	56	5	0a86656d48e4238d0e4d592d477d29f7ba7c2ec0
ToppCell	medial-mesenchymal-Alveolar_Fibroblast\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	A2M IGSF10 GRIA1 C1S ABCA8	5.25e-06	200	56	5	c22cbfecee00183dd4be678f116ab9fd9ad0a4dd
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	A2M IGSF10 MAP1B C1S ABCA8	5.25e-06	200	56	5	3fa7d9ea67f9cc55478d085da53babd03dbe9bb1
ToppCell	5'-Adult-SmallIntestine-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	A2M IGSF10 MAP1B C1S ABCA8	5.25e-06	200	56	5	a637281d91e95734ee4f8510b3780e0272b16fda
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	A2M GRIA1 C1S ABCA8 TBX5	5.25e-06	200	56	5	cb31cfcfa8e6d6cc610c4c22e97bc009dd8a9e7c
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA5 TET1 MUC16 BPIFB2 CDH12	5.25e-06	200	56	5	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	A2M MAP1B GRIA1 ABCA8 TBX5	5.25e-06	200	56	5	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	A2M IGSF10 GRIA1 C1S ABCA8	5.25e-06	200	56	5	8c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCell	3'-Parenchyma_lung-Mesenchymal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	A2M MAP1B C1S ABCA8 TBX5	5.25e-06	200	56	5	ba5ed66b05caa1be0bbf8d54c4e72a782b8d9833
ToppCell	Parenchymal-10x5prime-Stromal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	A2M MAP1B C1S ABCA8 TBX5	5.25e-06	200	56	5	2e525c0d9684e7a2275edb04e1addb6fc6a872e5
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	GABRG2 MAP1B ABCA5 GRIA1 ATP2B2	5.25e-06	200	56	5	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	medial-2-mesenchymal-Alveolar_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	A2M IGSF10 GRIA1 C1S ABCA8	5.25e-06	200	56	5	cc6062dac07916c29091fc6bee2b864d29e6525b
ToppCell	wk_08-11-Mesenchymal\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	A2M C1S SLITRK6 ABCA8 TBX5	5.25e-06	200	56	5	91416639e69621c5b36eebf061d81bccfe66f135
ToppCell	Lung_Parenchyma-Control-Mesenchymal\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	A2M IGSF10 MAP1B C1S ABCA8	5.25e-06	200	56	5	1e75d1302c22e1b1666c19c0c9259d5cc8be16d5
ToppCell	Biopsy_Other_PF-Mesenchymal\|Biopsy_Other_PF / Sample group, Lineage and Cell type	A2M MAP1B C1S ABCA8 TBX5	5.25e-06	200	56	5	d6fcdd48858b53b5a8d18ae14b2dc4d9af41b070
ToppCell	distal-3-mesenchymal-Alveolar_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	A2M IGSF10 GRIA1 C1S ABCA8	5.25e-06	200	56	5	20112be28f80baffad92641c9cfd7c3718967dbb
ToppCell	Mild/Remission-B_naive-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MCHR2 IQCN OGA ADGRG4	1.64e-05	121	56	4	68940a552233d255b90ce5a081339c0d9d46ab02
ToppCell	facs-Marrow-KLS-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCUBE1 ATP2B2 FCRL6 MUSK	4.22e-05	154	56	4	37765512dfae557b9f6eb30a29463b93682a4404
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA5 AFF1 SLITRK6 MUC4	4.33e-05	155	56	4	441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M TCEA2 NUP62CL CREM	4.90e-05	160	56	4	529034a1101d7772d82f86beb5c6fa9c9dd97067
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABCA5 PTPRQ ATP2B3 CDH12	5.14e-05	162	56	4	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	A2M SCUBE1 SLITRK6 TBX5	5.39e-05	164	56	4	e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell	-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	A2M GRIA1 C1S TBX5	6.06e-05	169	56	4	8ebe9a88111c53a09c25a7b6a164a0a17880458d
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	A2M C1S ABCA8 MUSK	6.06e-05	169	56	4	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	A2M MAP1B C1S ABCA8	6.49e-05	172	56	4	1ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	A2M MAP1B C1S ABCA8	6.49e-05	172	56	4	ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	A2M SCUBE1 SLITRK6 TBX5	6.63e-05	173	56	4	1f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EHHADH MUC16 BPIFB2 MUC4	6.78e-05	174	56	4	42f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2B2 ATP2B3	5.28e-05	6	56	2	DOID:0050429 (implicated_via_orthology)
Disease	cholesteryl esters to total lipids in medium HDL percentage	AFF1 ABCA8 MUSK	1.67e-04	56	56	3	EFO_0022251
Disease	autosomal dominant nonsyndromic deafness (is_implicated_in)	MAP1B ATP2B2	1.92e-04	11	56	2	DOID:0050564 (is_implicated_in)
Disease	colon cancer (implicated_via_orthology)	NANOGP8 NANOG	1.92e-04	11	56	2	DOID:219 (implicated_via_orthology)
Disease	cholangiocarcinoma (is_marker_for)	MUC16 MUC3A MUC4	2.49e-04	64	56	3	DOID:4947 (is_marker_for)
Disease	hepatic encephalopathy (biomarker_via_orthology)	GABRG2 GRIA1	3.66e-04	15	56	2	DOID:13413 (biomarker_via_orthology)
Disease	lip morphology measurement	RBBP6 MUC4 DNAH1 TBX5	4.62e-04	189	56	4	EFO_0007845
Disease	triglycerides:total lipids ratio, high density lipoprotein cholesterol measurement	AFF1 ABCA8 MUSK DNAH1	6.38e-04	206	56	4	EFO_0004612, EFO_0020947
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	TCEA2 AFF1 MUSK DNAH1	8.72e-04	224	56	4	EFO_0004530, EFO_0008317
Disease	urate measurement, bone density	GABRG2 CASP8AP2 ATP2B2 ABCA8 CDH12 DNAH1	1.11e-03	619	56	6	EFO_0003923, EFO_0004531
Disease	cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement	AFF1 ABCA8 MUSK DNAH1	1.18e-03	243	56	4	EFO_0004612, EFO_0020944
Disease	dihomo-gamma-linolenic acid measurement	NANOGP8 MUSK	1.20e-03	27	56	2	EFO_0007763
Disease	response to aromatase inhibitor	SVIL MUC16	1.69e-03	32	56	2	GO_0061477
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	AFF1 ABCA8 MUSK DNAH1	1.88e-03	276	56	4	EFO_0004612, EFO_0020943

Protein segments in the cluster

Peptide	Gene	Start	Entry
YTPVTNITSSIMQKV	ABCA5	81	Q8WWZ7
ETMLSSTITGRVYTQ	ADGRG4	596	Q8IZF6
SSMQVKTVAYVPSIS	CASP8AP2	596	Q9UKL3
RTTIAAMETISVPSY	TP53BP2	756	Q13625
TGTLTTNRMTVVQAY	ATP2B2	501	Q01814
GTLTTNRMTVVQSYL	ATP2B3	476	Q16720
TTNVMGTSLTVRVNY	A2M	411	P01023
VSVTLPQTYPASTMT	IQCN	346	Q9H0B3
STPISTFSRVQRMSI	MUC16	3671	Q8WXI7
SPSYSVTQMIKTATS	MUC4	581	Q99102
VTVTSVDLALQTPMY	OR10A7	46	Q8NGE5
TVTVMATTYRDPTTE	LRRTM2	366	O43300
QVSPVSEMTSTSLYQ	MAP1B	1441	P46821
MVTNTLFYVSSAVTP	NTSR2	341	O95665
TPVSALQYITTSSMT	IMPG1	551	Q17R60
QVMYIPQTFTQTSET	FCRL6	86	Q6DN72
IPSQYSSPTTIATVM	EHHADH	446	Q08426
VYTVSNMSARPTTVI	MUC3A	846	Q02505
LTSVYTVSSMSARPT	MUC3A	1596	Q02505
PTSISIQTTLTTYMD	MUC3A	2816	Q02505
LVQIPVSMYQTVVTS	NRF1	451	Q16656
VIQQTTRYFSTPQTM	NANOG	276	Q9H9S0
PYISSVTSQSVNLMI	INSIG2	16	Q9Y5U4
TPLVISMSYVITSLS	NPBWR2	291	P48146
SFPTVVIYVMDTSRS	GPN1	146	Q9HCN4
VIYVMDTSRSTNPVT	GPN1	151	Q9HCN4
TYVISRTEPAMATTK	RBBP6	86	Q7Z6E9
TTYTSPVTRIVTTNV	PTPRQ	81	Q9UMZ3
YQTASVVDTVILPSM	MCHR2	26	Q969V1
TIMVYATITSQLLPT	DNAH1	2416	Q9P2D7
TEISQVTPTGAVMTY	IGSF10	1131	Q6WRI0
TTVTSMTTPRCYVGA	KLHL12	501	Q53G59
SVTQQSPAAVSMETY	C2CD2L	166	O14523
PTMIYTVSSFSIKQT	CAPN7	271	Q9Y6W3
RSTTIVTAYVMTVTG	DUSP15	91	Q9H1R2
PSSVVLTSFQVMSRV	HACD2	101	Q6Y1H2
SSVYSTPVFSQKMTV	GABRG2	11	P18507
REPTMYVGSTSVQTS	C1S	481	P09871
YPVQSSTNTMTIRVC	CDH12	576	P55289
TTINFSRMPIVTRSS	FAM172BP	341	A6NC97
TYMKSAEPSVFVRTT	GRIA1	686	P42261
SIATMAVPTSIYQTS	CREM	151	Q03060
VMRKSASPTSITTYE	SCUBE1	856	Q8IWY4
MYQPSSVRVPSVTSV	PIAS2	506	O75928
TSYVRIVRTILQMPS	OR1D4	216	P47884
TSYVRIVRTILQMPS	OR1D5	216	P58170
PTQTSYLMVTTPATT	SLITRK6	576	Q9H5Y7
NTSVSTVASTVAPMY	SVIL	876	O95425
SYSSCTVTTVQPMDR	TBX5	406	Q99593
TTVVTTVYQEPIMSQ	OGA	426	O60502
VIQQTTRYFSTPQTM	NANOGP8	276	Q6NSW7
FSYTRIVSSVMKIPS	OR7G3	216	Q8NG95
VSTAMVQPYNSILTT	TUBA4B	116	Q9H853
VPMVSTSSSSYTTLL	TET1	566	Q8NFU7
SVVYTPVTNTTQQIM	ABCA8	76	O94911
SQIRYSMVSVPTVTS	BPIFB2	201	Q8N4F0
SMVSVPTVTSDYISL	BPIFB2	206	Q8N4F0
TISTPVTIQNMTSSY	AFF1	1131	P51825
AVTSMSVPTPIYQTS	ATF1	91	P18846
YTQVQTRSSDEPMTT	TCEA2	271	Q15560
FSVSPTYSMTVIISI	MUSK	486	O15146
TSTVSVVATPVMTYG	NUP62CL	61	Q9H1M0