Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein decrotonylase activity

HDAC3 HDAC1 HDAC2

3.05e-085303GO:0160008
GeneOntologyMolecularFunctionhistone decrotonylase activity

HDAC3 HDAC1 HDAC2

3.05e-085303GO:0160009
GeneOntologyMolecularFunctionprotein de-2-hydroxyisobutyrylase activity

HDAC3 HDAC2

2.18e-062302GO:0160010
GeneOntologyMolecularFunctionhistone deacetylase activity

HDAC3 HDAC1 HDAC2

6.06e-0624303GO:0004407
GeneOntologyMolecularFunctionKrueppel-associated box domain binding

HDAC1 HDAC2

6.54e-063302GO:0035851
GeneOntologyMolecularFunctionprotein lysine deacetylase activity

HDAC3 HDAC1 HDAC2

6.88e-0625303GO:0033558
GeneOntologyMolecularFunctionNF-kappaB binding

HDAC3 HDAC1 HDAC2

2.11e-0536303GO:0051059
GeneOntologyMolecularFunctiondeacetylase activity

HDAC3 HDAC1 HDAC2

2.91e-0540303GO:0019213
GeneOntologyMolecularFunctiontranscription corepressor binding

HDAC3 HDAC1 HDAC2

9.40e-0559303GO:0001222
GeneOntologyMolecularFunctionpore-forming activity

DEFA1 DEFA3

9.75e-0510302GO:0140911
GeneOntologyMolecularFunctioncollagen binding

COL6A1 MMP9 SRGN

2.41e-0481303GO:0005518
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

HDAC3 HDAC1 HDAC2

2.41e-0481303GO:0016811
GeneOntologyMolecularFunctionhistone modifying activity

JAK2 HDAC3 HDAC1 HDAC2

3.65e-04229304GO:0140993
GeneOntologyMolecularFunctiontranscription coregulator binding

HDAC3 HDAC1 HDAC2

1.19e-03140303GO:0001221
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

HDAC3 HDAC1 HDAC2

1.35e-03146303GO:0016810
GeneOntologyMolecularFunctionhistone deacetylase binding

HDAC3 HDAC1 HDAC2

1.37e-03147303GO:0042826
GeneOntologyMolecularFunctionchromatin DNA binding

HDAC3 HDAC1 HDAC2

1.98e-03167303GO:0031490
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

HDAC3 STING1 HDAC1 HDAC2

3.34e-03417304GO:0061629
GeneOntologyMolecularFunctionnucleosomal DNA binding

HDAC1 HDAC2

4.54e-0367302GO:0031492
GeneOntologyMolecularFunctionpromoter-specific chromatin binding

HDAC1 HDAC2

6.89e-0383302GO:1990841
GeneOntologyMolecularFunctionprotein domain specific binding

JAK2 CTNND1 HDAC1 L1CAM HDAC2

9.15e-03875305GO:0019904
GeneOntologyMolecularFunctionnucleosome binding

HDAC1 HDAC2

9.48e-0398302GO:0031491
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

HDAC3 STING1 HDAC1 HDAC2

1.07e-02582304GO:0140297
GeneOntologyBiologicalProcessfungiform papilla formation

HDAC1 HDAC2

1.58e-054342GO:0061198
GeneOntologyBiologicalProcesspositive regulation of signaling receptor activity

JAK2 HDAC1 HDAC2

2.16e-0533343GO:2000273
GeneOntologyBiologicalProcessdisruption of plasma membrane integrity in another organism

DEFA1 DEFA3

3.94e-056342GO:0051673
GeneOntologyBiologicalProcesshair follicle placode formation

HDAC1 HDAC2

3.94e-056342GO:0060789
GeneOntologyBiologicalProcessfungiform papilla morphogenesis

HDAC1 HDAC2

3.94e-056342GO:0061197
GeneOntologyBiologicalProcessdisruption of cellular anatomical structure in another organism

DEFA1 DEFA3

3.94e-056342GO:0140975
GeneOntologyBiologicalProcessfungiform papilla development

HDAC1 HDAC2

5.51e-057342GO:0061196
GeneOntologyBiologicalProcessprotein deacetylation

HDAC3 HDAC1 HDAC2

6.31e-0547343GO:0006476
GeneOntologyBiologicalProcessnuclear receptor-mediated steroid hormone signaling pathway

DEFA1 DEFA3 JAK2 HDAC1

7.19e-05136344GO:0030518
GeneOntologyBiologicalProcessresponse to bacterium

DEFA1 DEFA3 JAK2 COL6A1 RASGRP4 MMP9 DEFB123 HDAC2

9.51e-05916348GO:0009617
GeneOntologyBiologicalProcessresponse to lipopolysaccharide

DEFA1 DEFA3 JAK2 COL6A1 MMP9 HDAC2

9.89e-05464346GO:0032496
GeneOntologyBiologicalProcessprotein deacylation

HDAC3 HDAC1 HDAC2

1.19e-0458343GO:0035601
GeneOntologyBiologicalProcesssteroid hormone receptor signaling pathway

DEFA1 DEFA3 JAK2 HDAC1

1.19e-04155344GO:0043401
GeneOntologyBiologicalProcessresponse to molecule of bacterial origin

DEFA1 DEFA3 JAK2 COL6A1 MMP9 HDAC2

1.35e-04491346GO:0002237
GeneOntologyBiologicalProcessmacromolecule deacylation

HDAC3 HDAC1 HDAC2

1.52e-0463343GO:0098732
GeneOntologyBiologicalProcessskin epidermis development

HDAC3 COL6A1 HDAC1 HDAC2

1.55e-04166344GO:0098773
GeneOntologyBiologicalProcesstongue morphogenesis

HDAC1 HDAC2

1.72e-0412342GO:0043587
GeneOntologyBiologicalProcesspositive regulation of tyrosine phosphorylation of STAT protein

JAK2 HDAC2 HPX

1.99e-0469343GO:0042531
GeneOntologyBiologicalProcesscircadian regulation of gene expression

HDAC3 HDAC1 HDAC2

2.55e-0475343GO:0032922
GeneOntologyBiologicalProcesspositive regulation of peptidyl-tyrosine phosphorylation

JAK2 CTNND1 HDAC2 HPX

2.77e-04193344GO:0050731
GeneOntologyBiologicalProcessectodermal placode morphogenesis

HDAC1 HDAC2

3.12e-0416342GO:0071697
GeneOntologyBiologicalProcesseyelid development in camera-type eye

HDAC1 HDAC2

3.12e-0416342GO:0061029
GeneOntologyBiologicalProcessectodermal placode formation

HDAC1 HDAC2

3.12e-0416342GO:0060788
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

DEFA1 DEFA3 JAK2 HDAC1

3.29e-04202344GO:0141193
GeneOntologyBiologicalProcessregulation of tyrosine phosphorylation of STAT protein

JAK2 HDAC2 HPX

3.69e-0485343GO:0042509
GeneOntologyBiologicalProcessresponse to steroid hormone

DEFA1 DEFA3 JAK2 AGL HDAC1

3.75e-04381345GO:0048545
GeneOntologyBiologicalProcessresponse to lipid

DEFA1 DEFA3 JAK2 COL6A1 MMP9 AGL HDAC1 HDAC2

3.91e-041126348GO:0033993
GeneOntologyBiologicalProcessectodermal placode development

HDAC1 HDAC2

3.97e-0418342GO:0071696
GeneOntologyBiologicalProcesscellular response to organic cyclic compound

DEFA1 DEFA3 JAK2 STING1 HDAC1 HDAC2

4.15e-04605346GO:0071407
GeneOntologyBiologicalProcesstyrosine phosphorylation of STAT protein

JAK2 HDAC2 HPX

4.36e-0490343GO:0007260
GeneOntologyBiologicalProcessepithelial cell differentiation

COL6A1 CRYGD CTNND1 MMP9 CNMD HDAC1 HDAC2

4.60e-04870347GO:0030855
GeneOntologyBiologicalProcessepithelium development

JAK2 HDAC3 COL6A1 CRYGD CTNND1 MMP9 CNMD HDAC1 HDAC2

4.73e-041469349GO:0060429
GeneOntologyBiologicalProcessregulation of MHC class II biosynthetic process

JAK2 HDAC2

5.43e-0421342GO:0045346
GeneOntologyBiologicalProcessnegative regulation of myotube differentiation

HDAC3 HDAC1

5.43e-0421342GO:0010832
GeneOntologyBiologicalProcessintracellular receptor signaling pathway

DEFA1 DEFA3 JAK2 STING1 HDAC1

5.60e-04416345GO:0030522
GeneOntologyBiologicalProcessMHC class II biosynthetic process

JAK2 HDAC2

5.97e-0422342GO:0045342
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

DEFA1 DEFA3 JAK2 HDAC1

6.20e-04239344GO:0071383
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

DEFA1 DEFA3 JAK2 HDAC1

6.70e-04244344GO:0009755
GeneOntologyBiologicalProcessresponse to reactive oxygen species

COL6A1 CRYGD MMP9 HDAC2

6.91e-04246344GO:0000302
GeneOntologyBiologicalProcesscircadian rhythm

HDAC3 COL6A1 HDAC1 HDAC2

7.12e-04248344GO:0007623
GeneOntologyBiologicalProcessinterferon-mediated signaling pathway

JAK2 STING1 HPX

8.25e-04112343GO:0140888
GeneOntologyBiologicalProcessnegative regulation of stem cell population maintenance

HDAC1 HDAC2

8.36e-0426342GO:1902455
GeneOntologyBiologicalProcesstype II interferon-mediated signaling pathway

JAK2 HPX

9.02e-0427342GO:0060333
GeneOntologyBiologicalProcesstongue development

HDAC1 HDAC2

9.02e-0427342GO:0043586
GeneOntologyBiologicalProcessdefense response to Gram-negative bacterium

DEFA1 DEFA3 DEFB123

9.83e-04119343GO:0050829
GeneOntologyBiologicalProcessregulation of peptidyl-tyrosine phosphorylation

JAK2 CTNND1 HDAC2 HPX

1.00e-03272344GO:0050730
GeneOntologyBiologicalProcessregulation of cell fate specification

HDAC1 HDAC2

1.04e-0329342GO:0042659
GeneOntologyBiologicalProcessresponse to oxidative stress

JAK2 COL6A1 CRYGD MMP9 HDAC2

1.05e-03478345GO:0006979
GeneOntologyBiologicalProcesspositive regulation of protein phosphorylation

JAK2 HDAC3 CTNND1 MMP9 HDAC2 HPX

1.06e-03724346GO:0001934
GeneOntologyBiologicalProcesshair follicle development

COL6A1 HDAC1 HDAC2

1.08e-03123343GO:0001942
GeneOntologyBiologicalProcessinnate immune response in mucosa

DEFA1 DEFA3

1.11e-0330342GO:0002227
GeneOntologyBiologicalProcessmolting cycle process

COL6A1 HDAC1 HDAC2

1.16e-03126343GO:0022404
GeneOntologyBiologicalProcesshair cycle process

COL6A1 HDAC1 HDAC2

1.16e-03126343GO:0022405
GeneOntologyBiologicalProcessnegative regulation of intrinsic apoptotic signaling pathway

MMP9 HDAC1 HDAC2

1.19e-03127343GO:2001243
GeneOntologyBiologicalProcesscellular response to lipid

DEFA1 DEFA3 JAK2 MMP9 HDAC1 HDAC2

1.26e-03748346GO:0071396
GeneOntologyBiologicalProcessregulation of signaling receptor activity

JAK2 HDAC1 HDAC2

1.30e-03131343GO:0010469
GeneOntologyBiologicalProcessresponse to organic cyclic compound

DEFA1 DEFA3 JAK2 STING1 AGL HDAC1 HDAC2

1.38e-031048347GO:0014070
GeneOntologyBiologicalProcesspositive regulation of oligodendrocyte differentiation

HDAC1 HDAC2

1.43e-0334342GO:0048714
GeneOntologyBiologicalProcesspositive regulation of smooth muscle cell proliferation

JAK2 MMP9 HDAC1

1.51e-03138343GO:0048661
GeneOntologyBiologicalProcesspositive regulation of phosphorylation

JAK2 HDAC3 CTNND1 MMP9 HDAC2 HPX

1.56e-03780346GO:0042327
GeneOntologyBiologicalProcessresponse to xenobiotic stimulus

DEFA1 DEFA3 COL6A1 MMP9 HDAC2

1.58e-03525345GO:0009410
GeneOntologyBiologicalProcessinnate immune response

DEFA1 DEFA3 JAK2 RASGRP4 STING1 DEFB123 HPX

1.75e-031092347GO:0045087
GeneOntologyBiologicalProcesscellular response to lipopolysaccharide

DEFA1 DEFA3 JAK2 MMP9

1.79e-03318344GO:0071222
GeneOntologyBiologicalProcesscollagen metabolic process

COL6A1 MMP9 HDAC2

1.84e-03148343GO:0032963
GeneOntologyBiologicalProcessmolting cycle

COL6A1 HDAC1 HDAC2

1.91e-03150343GO:0042303
GeneOntologyBiologicalProcesshair cycle

COL6A1 HDAC1 HDAC2

1.91e-03150343GO:0042633
GeneOntologyBiologicalProcesspeptidyl-tyrosine phosphorylation

JAK2 CTNND1 HDAC2 HPX

1.98e-03327344GO:0018108
GeneOntologyBiologicalProcesspeptidyl-tyrosine modification

JAK2 CTNND1 HDAC2 HPX

2.02e-03329344GO:0018212
GeneOntologyBiologicalProcessmuscle cell proliferation

JAK2 MMP9 HDAC1 HDAC2

2.02e-03329344GO:0033002
GeneOntologyBiologicalProcessnegative regulation of canonical Wnt signaling pathway

CTNND1 HDAC1 HDAC2

2.06e-03154343GO:0090090
GeneOntologyBiologicalProcesscellular response to molecule of bacterial origin

DEFA1 DEFA3 JAK2 MMP9

2.09e-03332344GO:0071219
GeneOntologyBiologicalProcesscanonical Wnt signaling pathway

COL6A1 CTNND1 HDAC1 HDAC2

2.38e-03344344GO:0060070
GeneOntologyBiologicalProcessresponse to antibiotic

JAK2 HDAC2

2.39e-0344342GO:0046677
GeneOntologyBiologicalProcessmyotube differentiation

HDAC3 COL6A1 HDAC1

2.46e-03164343GO:0014902
GeneOntologyBiologicalProcessregulation of interleukin-1 production

JAK2 HDAC3 HDAC2

2.51e-03165343GO:0032652
GeneOntologyBiologicalProcessinterleukin-1 production

JAK2 HDAC3 HDAC2

2.77e-03171343GO:0032612
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

JAK2 COL6A1 MMP9 ATXN7 CNMD HDAC1 HDAC2

2.79e-031186347GO:0007167
GeneOntologyBiologicalProcessrhythmic process

HDAC3 COL6A1 HDAC1 HDAC2

2.80e-03360344GO:0048511
GeneOntologyBiologicalProcessintrinsic apoptotic signaling pathway

JAK2 MMP9 HDAC1 HDAC2

2.83e-03361344GO:0097193
GeneOntologyBiologicalProcessmucosal immune response

DEFA1 DEFA3

2.84e-0348342GO:0002385
GeneOntologyBiologicalProcesspositive regulation of phosphate metabolic process

JAK2 HDAC3 CTNND1 MMP9 HDAC2 HPX

2.85e-03879346GO:0045937
GeneOntologyBiologicalProcesspositive regulation of phosphorus metabolic process

JAK2 HDAC3 CTNND1 MMP9 HDAC2 HPX

2.85e-03879346GO:0010562
GeneOntologyBiologicalProcesscell morphogenesis

COL6A1 FRYL TENM2 CNMD BTBD3 LRATD1 L1CAM

2.90e-031194347GO:0000902
GeneOntologyBiologicalProcesscellular response to biotic stimulus

DEFA1 DEFA3 JAK2 MMP9

2.91e-03364344GO:0071216
GeneOntologyBiologicalProcesscellular response to reactive oxygen species

CRYGD MMP9 HDAC2

3.11e-03178343GO:0034614
GeneOntologyBiologicalProcessskin development

HDAC3 COL6A1 HDAC1 HDAC2

3.18e-03373344GO:0043588
GeneOntologyCellularComponentsite of polarized growth

GDPD5 FRYL CTNND1 TENM2 L1CAM

5.21e-05253345GO:0030427
GeneOntologyCellularComponentsecretory granule lumen

A1BG DEFA1 DEFA3 SRGN AGL

1.69e-04325345GO:0034774
GeneOntologyCellularComponentsecretory granule

A1BG DEFA1 DEFA3 STING1 FCAR MMP9 SRGN AGL

1.75e-041014348GO:0030141
GeneOntologyCellularComponentcytoplasmic vesicle lumen

A1BG DEFA1 DEFA3 SRGN AGL

1.82e-04330345GO:0060205
GeneOntologyCellularComponentvesicle lumen

A1BG DEFA1 DEFA3 SRGN AGL

1.87e-04332345GO:0031983
GeneOntologyCellularComponentcollagen-containing extracellular matrix

A1BG DEFA1 COL6A1 MMP9 L1CAM HPX

1.90e-04530346GO:0062023
GeneOntologyCellularComponentficolin-1-rich granule

A1BG FCAR MMP9 AGL

2.24e-04185344GO:0101002
GeneOntologyCellularComponentCHD-type complex

HDAC1 HDAC2

3.44e-0417342GO:0090545
GeneOntologyCellularComponentNuRD complex

HDAC1 HDAC2

3.44e-0417342GO:0016581
GeneOntologyCellularComponenthistone deacetylase complex

HDAC3 HDAC1 HDAC2

3.54e-0485343GO:0000118
GeneOntologyCellularComponenttranscription repressor complex

HDAC3 HDAC1 HDAC2

3.80e-0487343GO:0017053
GeneOntologyCellularComponentmidbody

DEFA1 DEFA3 CTNND1 EML3

4.47e-04222344GO:0030496
GeneOntologyCellularComponentSin3-type complex

HDAC1 HDAC2

5.81e-0422342GO:0070822
GeneOntologyCellularComponentextracellular matrix

A1BG DEFA1 COL6A1 MMP9 L1CAM HPX

5.93e-04656346GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

A1BG DEFA1 COL6A1 MMP9 L1CAM HPX

6.02e-04658346GO:0030312
GeneOntologyCellularComponentgrowth cone

GDPD5 CTNND1 TENM2 L1CAM

6.48e-04245344GO:0030426
GeneOntologyCellularComponentsecretory vesicle

A1BG DEFA1 DEFA3 STING1 FCAR MMP9 SRGN AGL

7.03e-041246348GO:0099503
GeneOntologyCellularComponentficolin-1-rich granule lumen

A1BG MMP9 AGL

1.07e-03124343GO:1904813
GeneOntologyCellularComponentextrinsic component of plasma membrane

JAK2 CTNND1 TENM2

1.42e-03137343GO:0019897
GeneOntologyCellularComponentvacuole

DEFA1 DEFA3 COL6A1 STING1 SRGN ABCC10

3.22e-03913346GO:0005773
GeneOntologyCellularComponentdistal axon

GDPD5 CTNND1 TENM2 L1CAM

5.23e-03435344GO:0150034
GeneOntologyCellularComponentplatelet alpha granule lumen

A1BG SRGN

5.31e-0367342GO:0031093
GeneOntologyCellularComponentextrinsic component of membrane

JAK2 CTNND1 TENM2

6.12e-03230343GO:0019898
DomainHis_deacetylse_1

HDAC3 HDAC1 HDAC2

2.20e-084343IPR003084
DomainHis_deacetylse_dom

HDAC3 HDAC1 HDAC2

9.00e-0711343IPR023801
DomainHist_deacetyl

HDAC3 HDAC1 HDAC2

9.00e-0711343PF00850
Domain-

HDAC3 HDAC1 HDAC2

9.00e-07113433.40.800.20
DomainHis_deacetylse

HDAC3 HDAC1 HDAC2

9.00e-0711343IPR000286
DomainDefensin_propep

DEFA1 DEFA3

3.21e-055342PF00879
DomainPHR

BTBD6 BTBD3

3.21e-055342PF08005
DomainAlpha-defensin_pro

DEFA1 DEFA3

3.21e-055342IPR016327
DomainPHR

BTBD6 BTBD3

3.21e-055342IPR012983
DomainDEFENSIN

DEFA1 DEFA3

3.21e-055342PS00269
DomainAlpha-defensin

DEFA1 DEFA3

3.21e-055342IPR006081
DomainDefensin_propep

DEFA1 DEFA3

3.21e-055342IPR002366
DomainDefensin_1

DEFA1 DEFA3

3.21e-055342PF00323
DomainDefensin_beta/alpha

DEFA1 DEFA3

8.95e-058342IPR006080
DomainDEFSN

DEFA1 DEFA3

8.95e-058342SM00048
DomainHemopexin_CS

MMP9 HPX

4.30e-0417342IPR018486
DomainHemopexin-like_dom

MMP9 HPX

7.95e-0423342IPR000585
DomainHemopexin

MMP9 HPX

7.95e-0423342PF00045
DomainHEMOPEXIN

MMP9 HPX

7.95e-0423342PS00024
Domain-

MMP9 HPX

7.95e-04233422.110.10.10
DomainHEMOPEXIN_2

MMP9 HPX

7.95e-0423342PS51642
DomainHemopexin-like_repeat

MMP9 HPX

7.95e-0423342IPR018487
DomainHX

MMP9 HPX

7.95e-0423342SM00120
DomainBACK

BTBD6 BTBD3

5.33e-0360342SM00875
DomainBACK

BTBD6 BTBD3

5.50e-0361342PF07707
DomainBACK

BTBD6 BTBD3

5.50e-0361342IPR011705
PathwayREACTOME_P75NTR_NEGATIVELY_REGULATES_CELL_CYCLE_VIA_SC1

HDAC3 HDAC1 HDAC2

1.11e-076263M27072
PathwayKEGG_MEDICUS_VARIANT_TEL_AML1_FUSION_TO_TRANSCRIPTIONAL_REPRESSION

DEFA3 HDAC1 HDAC2

9.10e-0711263M47438
PathwayREACTOME_STAT3_NUCLEAR_EVENTS_DOWNSTREAM_OF_ALK_SIGNALING

HDAC3 HDAC1 HDAC2

9.10e-0711263M42523
PathwayBIOCARTA_CARM_ER_PATHWAY

HDAC3 HDAC1 HDAC2

1.41e-0526263M2499
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

HDAC3 HDAC1 HDAC2

1.77e-0528263M6177
PathwayREACTOME_SIGNALING_BY_ALK

HDAC3 HDAC1 HDAC2

2.19e-0530263M42517
PathwayWP_ETHANOL_EFFECTS_ON_HISTONE_MODIFICATIONS

HDAC3 HDAC1 HDAC2

2.42e-0531263M39714
PathwayREACTOME_DEFENSINS

DEFA1 DEFA3 DEFB123

2.42e-0531263MM14568
PathwayWP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR

HDAC3 HDAC1 HDAC2

2.67e-0532263M39521
PathwayREACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY

HDAC3 HDAC1 HDAC2

2.67e-0532263M27900
PathwayWP_HISTONE_MODIFICATIONS

HDAC1 HDAC2

3.26e-055262MM15874
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

JAK2 HDAC3 COL6A1 CTNND1 MMP9 HDAC1 HDAC2

3.69e-05532267M27870
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_REST_MEDIATED_TRANSCRIPTIONAL_REPRESSION

HDAC1 HDAC2

6.83e-057262M47673
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

JAK2 HDAC3 COL6A1 CTNND1 MMP9 HDAC1

9.12e-05418266MM15587
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

HDAC3 HDAC1 HDAC2

9.12e-0548263M611
PathwayREACTOME_INNATE_IMMUNE_SYSTEM

A1BG DEFA1 DEFA3 RASGRP4 STING1 FCAR MMP9 AGL DEFB123

1.17e-041128269M1036
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

JAK2 HDAC3 ATXN7 HDAC1 HDAC2

1.22e-04272265M29619
PathwayREACTOME_DEFENSINS

DEFA1 DEFA3 DEFB123

1.23e-0453263M557
PathwayREACTOME_ALPHA_DEFENSINS

DEFA1 DEFA3

1.46e-0410262M26955
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

HDAC3 HDAC1 HDAC2

1.61e-0458263M29616
PathwayREACTOME_ALPHA_DEFENSINS

DEFA1 DEFA3

1.78e-0411262MM14569
PathwayWP_NOTCH_SIGNALING_WP61

JAK2 HDAC1 HDAC2

1.87e-0461263M39540
PathwayREACTOME_REGULATION_OF_PTEN_GENE_TRANSCRIPTION

HDAC3 HDAC1 HDAC2

1.87e-0461263M27811
PathwayREACTOME_NEUTROPHIL_DEGRANULATION

A1BG DEFA1 STING1 FCAR MMP9 AGL

1.90e-04478266M27620
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2

HDAC3 HDAC1 HDAC2

2.06e-0463263M27862
PathwayPID_HDAC_CLASSI_PATHWAY

HDAC3 HDAC1 HDAC2

2.36e-0466263M101
PathwayREACTOME_LOSS_OF_FUNCTION_OF_MECP2_IN_RETT_SYNDROME

HDAC3 HDAC1

2.52e-0413262M29766
PathwayREACTOME_NEUTROPHIL_DEGRANULATION

A1BG DEFA1 DEFA3 STING1 MMP9 AGL

2.73e-04511266MM15330
PathwayREACTOME_ANTIMICROBIAL_PEPTIDES

DEFA1 DEFA3 DEFB123

2.81e-0470263MM15332
PathwayBIOCARTA_PRC2_PATHWAY

HDAC1 HDAC2

2.94e-0414262M22025
PathwayREACTOME_SIGNALING_BY_NOTCH1

HDAC3 HDAC1 HDAC2

3.31e-0474263M616
PathwayWP_ESTROGEN_SIGNALING

HDAC3 HDAC1 HDAC2

3.72e-0477263MM15934
PathwayPID_BETA_CATENIN_NUC_PATHWAY

MMP9 HDAC1 HDAC2

4.16e-0480263M223
PathwayREACTOME_SIGNALING_BY_ALK

HDAC3 HDAC1

4.37e-0417262MM14790
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

JAK2 HDAC1 HDAC2

4.48e-0482263MM15922
PathwayWP_TRANSCRIPTION_COFACTORS_SKI_AND_SKIL_PROTEIN_PARTNERS

HDAC3 HDAC1

4.91e-0418262M39825
PathwayBIOCARTA_MEF2D_PATHWAY

HDAC1 HDAC2

4.91e-0418262M5290
PathwayREACTOME_MECP2_REGULATES_NEURONAL_RECEPTORS_AND_CHANNELS

HDAC1 HDAC2

4.91e-0418262M27901
PathwayWP_CALCIUM_MEDIATED_TCELL_APOPTOSIS_INVOLVED_IN_INCLUSION_BODY_MYOSITIS

HDAC1 HDAC2

6.09e-0420262M48330
PathwayREACTOME_HDACS_DEACETYLATE_HISTONES

HDAC3 HDAC1 HDAC2

6.68e-0494263M27230
PathwayWP_NEURAL_CREST_DIFFERENTIATION

HDAC3 HDAC1 HDAC2

7.32e-0497263MM15926
PathwayREACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING

HDAC3 HDAC1 HDAC2

7.32e-0497263M9400
PathwayREACTOME_ANTIMICROBIAL_PEPTIDES

DEFA1 DEFA3 DEFB123

7.54e-0498263M27627
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

HDAC3 HDAC1

8.08e-0423262MM14954
PathwayWP_NEURAL_CREST_DIFFERENTIATION

HDAC3 HDAC1 HDAC2

8.23e-04101263M39448
PathwayPID_IL3_PATHWAY

JAK2 HDAC1

1.03e-0326262M182
PathwayREACTOME_ADIPOGENESIS

HDAC3 HDAC1 HDAC2

1.05e-03110263M48259
PathwayKEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119_IN_GERMLINE_GENES

HDAC1 HDAC2

1.12e-0327262M47941
PathwayREACTOME_HEMOSTASIS

A1BG JAK2 SRGN HDAC1 L1CAM HDAC2

1.23e-03679266M8395
PathwayPID_RETINOIC_ACID_PATHWAY

HDAC3 HDAC1

1.38e-0330262M207
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION

HDAC1 HDAC2

1.38e-0330262M27637
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_OXIDATIVE_STRESS_METABOLIC_AND_NEURONAL_GENES

HDAC1 HDAC2

1.38e-0330262M27941
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_BROWN_AND_BEIGE_ADIPOCYTE_DIFFERENTIATION

HDAC1 HDAC2

1.47e-0331262M48258
PathwayREACTOME_INNATE_IMMUNE_SYSTEM

A1BG DEFA1 DEFA3 STING1 MMP9 AGL DEFB123

1.71e-03995267MM14661
PathwayWP_FATTY_ACID_BETAOXIDATION

LIPF CHKB

1.77e-0334262M39596
PathwayWP_FATTY_ACID_BETAOXIDATION

LIPF CHKB

1.77e-0334262MM15937
PathwayREACTOME_PTEN_REGULATION

HDAC3 HDAC1 HDAC2

2.07e-03139263M27646
PathwayWP_EFFECT_OF_PROGERIN_ON_GENES_INVOLVED_IN_PROGERIA

HDAC1 HDAC2

2.09e-0337262M39756
PathwayREACTOME_SIGNALING_BY_SCF_KIT

JAK2 MMP9

2.09e-0337262MM14564
PathwayWP_TNFRELATED_WEAK_INDUCER_OF_APOPTOSIS_TWEAK_SIGNALING

MMP9 HDAC1

2.69e-0342262M39452
PathwayREACTOME_DEATH_RECEPTOR_SIGNALING

HDAC3 HDAC1 HDAC2

2.76e-03154263M27697
PathwayREACTOME_POTENTIAL_THERAPEUTICS_FOR_SARS

JAK2 HDAC1 HDAC2

2.76e-03154263M39007
PathwayWP_IL6_SIGNALING

JAK2 HDAC1

2.82e-0343262M39656
PathwayREACTOME_SIGNALING_BY_SCF_KIT

JAK2 MMP9

2.82e-0343262M508
PathwayWP_NOTCH_SIGNALING_WP268

HDAC1 HDAC2

3.08e-0345262M39571
PathwayPID_SYNDECAN_1_PATHWAY

COL6A1 MMP9

3.22e-0346262M198
PathwayWP_NOTCH_SIGNALING_PATHWAY

HDAC1 HDAC2

3.22e-0346262MM15971
PathwayWP_IL26_SIGNALING

JAK2 MMP9

3.36e-0347262M48074
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

HDAC1 HDAC2

3.36e-0347262M7946
PathwayREACTOME_RNA_POLYMERASE_I_TRANSCRIPTION_INITIATION

HDAC1 HDAC2

3.36e-0347262M1095
PathwayPID_HEDGEHOG_GLI_PATHWAY

HDAC1 HDAC2

3.50e-0348262M219
PathwayPID_HES_HEY_PATHWAY

JAK2 HDAC1

3.50e-0348262M288
PathwayREACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION

JAK2 HDAC1 HDAC2

3.65e-03170263M941
PathwayWP_OSTEOARTHRITIC_CHONDROCYTE_HYPERTROPHY

JAK2 CNMD

3.79e-0350262M48087
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL6A1 MMP9

3.79e-0350262MM14796
PathwayREACTOME_COLLAGEN_DEGRADATION

COL6A1 MMP9

4.25e-0353262MM14566
PathwayREACTOME_HDACS_DEACETYLATE_HISTONES

HDAC3 HDAC1

4.57e-0355262MM14932
PathwayPID_FGF_PATHWAY

CTNND1 MMP9

4.57e-0355262M276
PathwayWP_EGFR1_SIGNALING_PATHWAY

JAK2 CTNND1 HDAC1

4.84e-03188263MM15828
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL6A1 MMP9

5.60e-0361262M27103
PathwayWP_CIRCADIAN_RHYTHM_GENES

HDAC3 HDAC1 HDAC2

5.83e-03201263M39605
PathwayPID_MYC_REPRESS_PATHWAY

HDAC3 HDAC1

5.96e-0363262M254
PathwayREACTOME_COLLAGEN_DEGRADATION

COL6A1 MMP9

6.15e-0364262M26953
PathwayPID_RB_1PATHWAY

HDAC3 HDAC1

6.34e-0365262M279
PathwayWP_AGERAGE_PATHWAY

JAK2 MMP9

6.53e-0366262M39420
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION

HDAC1 HDAC2

6.53e-0366262M27938
Pubmed

Class I histone deacetylases 1, 2 and 3 are highly expressed in renal cell cancer.

HDAC3 HDAC1 HDAC2

8.54e-10334319099586
Pubmed

Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy.

HDAC3 HDAC1 HDAC2

8.54e-10334318212746
Pubmed

Combination of polymorphisms within the HDAC1 and HDAC3 gene predict tumor recurrence in hepatocellular carcinoma patients that have undergone transplant therapy.

HDAC3 HDAC1 HDAC2

8.54e-10334320731616
Pubmed

The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB.

HDAC3 HDAC1 HDAC2

8.54e-10334323087373
Pubmed

Retinoic acid and histone deacetylases regulate epigenetic changes in embryonic stem cells.

HDAC3 HDAC1 HDAC2

8.54e-10334324821725
Pubmed

Histone deacetylase 1 (HDAC1) regulates histone acetylation, development, and gene expression in preimplantation mouse embryos.

HDAC3 HDAC1 HDAC2

8.54e-10334318501342
Pubmed

HDAC inhibition activates the apoptosome via Apaf1 upregulation in hepatocellular carcinoma.

HDAC3 HDAC1 HDAC2

8.54e-10334327342975
Pubmed

Expression of histone deacetylases 1, 2 and 3 in histological subtypes of testicular germ cell tumours.

HDAC3 HDAC1 HDAC2

8.54e-10334321972094
Pubmed

Downregulation of Cell Cycle and Checkpoint Genes by Class I HDAC Inhibitors Limits Synergism with G2/M Checkpoint Inhibitor MK-1775 in Bladder Cancer Cells.

HDAC3 HDAC1 HDAC2

8.54e-10334333670166
Pubmed

Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone acetylation and crotonylation in vivo.

HDAC3 HDAC1 HDAC2

8.54e-10334330279482
Pubmed

HDAC1/2 and HDAC3 play distinct roles in controlling adult Meibomian gland homeostasis.

HDAC3 HDAC1 HDAC2

8.54e-10334338679196
Pubmed

Frequent amplification of HDAC genes and efficacy of HDAC inhibitor chidamide and PD-1 blockade combination in soft tissue sarcoma.

HDAC3 HDAC1 HDAC2

8.54e-10334333637599
Pubmed

Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: specific role of class I histone deacetylases in vitro and in vivo.

HDAC3 HDAC1 HDAC2

8.54e-10334318347167
Pubmed

Expression patterns of histone deacetylases in bovine oocytes and early embryos, and the effect of their inhibition on embryo development.

HDAC3 HDAC1 HDAC2

8.54e-10334311358320
Pubmed

Class I HDAC inhibition blocks cocaine-induced plasticity by targeted changes in histone methylation.

HDAC3 HDAC1 HDAC2

8.54e-10334323475113
Pubmed

Class I histone deacetylases 1, 2 and 3 are highly expressed in classical Hodgkin's lymphoma.

HDAC3 HDAC1 HDAC2

8.54e-10334320415600
Pubmed

Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family.

HDAC3 HDAC1 HDAC2

3.41e-0943439346952
Pubmed

Histone deacetylases specifically down-regulate p53-dependent gene activation.

HDAC3 HDAC1 HDAC2

3.41e-09434310777477
Pubmed

HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury.

HDAC3 HDAC1 HDAC2

3.41e-09434333907245
Pubmed

Class I HDAC activity is required for renal protection and regeneration after acute kidney injury.

HDAC3 HDAC1 HDAC2

3.41e-09434324808536
Pubmed

Ovol1 represses its own transcription by competing with transcription activator c-Myb and by recruiting histone deacetylase activity.

HDAC3 HDAC1 HDAC2

3.41e-09434317311813
Pubmed

The growth suppressor PML represses transcription by functionally and physically interacting with histone deacetylases.

HDAC3 HDAC1 HDAC2

3.41e-09434311259576
Pubmed

Histone deacetylase 3 binds to and regulates the multifunctional transcription factor TFII-I.

HDAC3 HDAC1 HDAC2

3.41e-09434312393887
Pubmed

Class I histone deacetylase activity is required for proliferation of renal epithelial cells.

HDAC3 HDAC1 HDAC2

3.41e-09434323698124
Pubmed

High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo.

HDAC3 HDAC1 HDAC2

3.41e-09434319912635
Pubmed

Histone acetylation regulates prostate ductal morphogenesis through a bone morphogenetic protein-dependent mechanism.

HDAC3 HDAC1 HDAC2

3.41e-09434326283270
Pubmed

Expression profile of class I histone deacetylases in human cancer tissues.

HDAC3 HDAC1 HDAC2

3.41e-09434317786334
Pubmed

The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E.

HDAC3 HDAC1 HDAC2

3.41e-09434315051733
Pubmed

Expression of class I histone deacetylases during chick and mouse development.

HDAC3 HDAC1 HDAC2

3.41e-09434320979029
Pubmed

Sequestration and inhibition of Daxx-mediated transcriptional repression by PML.

HDAC3 HDAC1 HDAC2

8.52e-09534310669754
Pubmed

Class I HDACs specifically regulate E-cadherin expression in human renal epithelial cells.

HDAC3 HDAC1 HDAC2

8.52e-09534327420561
Pubmed

GATA3 acetylation at K119 by CBP inhibits cell migration and invasion in lung adenocarcinoma.

HDAC3 HDAC1 HDAC2

8.52e-09534329453984
Pubmed

Histone deacetylases activate hepatocyte growth factor signaling by repressing microRNA-449 in hepatocellular carcinoma cells.

HDAC3 HDAC1 HDAC2

8.52e-09534322641068
Pubmed

Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.

HDAC3 HDAC1 HDAC2

8.52e-09534326447190
Pubmed

Histone deacetylase-3 activation promotes tumor necrosis factor-alpha (TNF-alpha) expression in cardiomyocytes during lipopolysaccharide stimulation.

HDAC3 HDAC1 HDAC2

8.52e-09534320097764
Pubmed

Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation.

HDAC3 HDAC1 HDAC2

8.52e-09534310581039
Pubmed

Expression of nuclear receptor corepressors and class I histone deacetylases in astrocytic gliomas.

HDAC3 HDAC1 HDAC2

8.52e-09534321143702
Pubmed

Histone cross-talk connects protein phosphatase 1α (PP1α) and histone deacetylase (HDAC) pathways to regulate the functional transition of bromodomain-containing 4 (BRD4) for inducible gene expression.

HDAC3 HDAC1 HDAC2

8.52e-09534324939842
Pubmed

Cytoplasmic IkappaBalpha increases NF-kappaB-independent transcription through binding to histone deacetylase (HDAC) 1 and HDAC3.

HDAC3 HDAC1 HDAC2

8.52e-09534312972430
Pubmed

N-Myc-interacting protein (NMI) negatively regulates epithelial-mesenchymal transition by inhibiting the acetylation of NF-κB/p65.

HDAC3 HDAC1 HDAC2

8.52e-09534327012186
Pubmed

Immediate effects of a single exercise bout on protein O-GlcNAcylation and chromatin regulation of cardiac hypertrophy.

HDAC3 HDAC1 HDAC2

8.52e-09534323624624
Pubmed

HDAC3 selectively represses CREB3-mediated transcription and migration of metastatic breast cancer cells.

HDAC3 HDAC1 HDAC2

8.52e-09534320473547
Pubmed

LZAP, a putative tumor suppressor, selectively inhibits NF-kappaB.

HDAC3 HDAC1 HDAC2

8.52e-09534317785205
Pubmed

Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription.

HDAC3 HDAC1 HDAC2

8.52e-09534328497810
Pubmed

Identification and mapping of human histone acetylation modifier gene homologues.

HDAC3 HDAC1 HDAC2

8.52e-0953439722949
Pubmed

HDAC3 Deficiency Promotes Liver Cancer through a Defect in H3K9ac/H3K9me3 Transition.

HDAC3 HDAC1 HDAC2

8.52e-09534331097476
Pubmed

WDR5 facilitates EMT and metastasis of CCA by increasing HIF-1α accumulation in Myc-dependent and independent pathways.

HDAC3 HDAC1 HDAC2

8.52e-09534333601056
Pubmed

Autoacetylation regulates P/CAF nuclear localization.

HDAC3 HDAC1 HDAC2

8.52e-09534319015268
Pubmed

Recruitment of chromatin-modifying enzymes by CTIP2 promotes HIV-1 transcriptional silencing.

HDAC3 HDAC1 HDAC2

8.52e-09534317245431
Pubmed

Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment.

HDAC3 HDAC1 HDAC2

8.52e-09534315713663
Pubmed

Role of NonO-histone interaction in TNFalpha-suppressed prolyl-4-hydroxylase alpha1.

HDAC3 HDAC1 HDAC2

8.52e-09534318439917
Pubmed

EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin.

HDAC3 HDAC1 HDAC2

1.70e-08634321685935
Pubmed

RBP1 recruits both histone deacetylase-dependent and -independent repression activities to retinoblastoma family proteins.

HDAC3 HDAC1 HDAC2

1.70e-08634310490602
Pubmed

Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein.

HDAC3 HDAC1 HDAC2

1.70e-08634315927959
Pubmed

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity.

HDAC3 HDAC1 HDAC2

1.70e-08634311641274
Pubmed

Functional and physical interaction between the histone methyl transferase Suv39H1 and histone deacetylases.

HDAC3 HDAC1 HDAC2

1.70e-08634311788710
Pubmed

Human class I histone deacetylase complexes show enhanced catalytic activity in the presence of ATP and co-immunoprecipitate with the ATP-dependent chaperone protein Hsp70.

HDAC3 HDAC1 HDAC2

1.70e-08634311777905
Pubmed

HIV-1 Vpr Protein Induces Proteasomal Degradation of Chromatin-associated Class I HDACs to Overcome Latent Infection of Macrophages.

HDAC3 HDAC1 HDAC2

1.70e-08634326679995
Pubmed

Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene.

HDAC3 HDAC1 HDAC2

1.70e-08634314633989
Pubmed

Control of the cell cycle by neurotrophins: lessons from the p75 neurotrophin receptor.

HDAC3 HDAC1 HDAC2

1.70e-08634312371150
Pubmed

TBX3 is overexpressed in breast cancer and represses p14 ARF by interacting with histone deacetylases.

HDAC3 HDAC1 HDAC2

1.70e-08634318245468
Pubmed

The balance between acetylation and deacetylation controls Smad7 stability.

HDAC3 HDAC1 HDAC2

1.70e-08634315831498
Pubmed

SAP30L interacts with members of the Sin3A corepressor complex and targets Sin3A to the nucleolus.

HDAC3 HDAC1 HDAC2

1.70e-08634316820529
Pubmed

Homo-oligomerisation and nuclear localisation of mouse histone deacetylase 1.

HDAC3 HDAC1 HDAC2

1.70e-08634311302704
Pubmed

Stat3 dimerization regulated by reversible acetylation of a single lysine residue.

HDAC3 HDAC1 HDAC2

1.70e-08634315653507
Pubmed

Histone deacetylase-associating Atrophin proteins are nuclear receptor corepressors.

HDAC3 HDAC1 HDAC2

2.98e-08734316481466
Pubmed

Class I histone deacetylases in retinal progenitors and differentiating ganglion cells.

HDAC3 HDAC1 HDAC2

2.98e-08734330179675
Pubmed

Sumoylation of p68 and p72 RNA helicases affects protein stability and transactivation potential.

HDAC3 HDAC1 HDAC2

2.98e-08734319995069
Pubmed

HDAC4 mediates transcriptional repression by the acute promyelocytic leukaemia-associated protein PLZF.

HDAC3 HDAC1 HDAC2

2.98e-08734315467736
Pubmed

A calcium-dependent switch in a CREST-BRG1 complex regulates activity-dependent gene expression.

HDAC3 HDAC1 HDAC2

2.98e-08734319081374
Pubmed

Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth.

HDAC3 HDAC1 HDAC2

2.98e-08734317182846
Pubmed

The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling.

HDAC3 HDAC1 HDAC2

2.98e-08734311867749
Pubmed

Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65.

HDAC3 HDAC1 HDAC2

2.98e-08734312419806
Pubmed

NF-kappaB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK.

HDAC3 HDAC1 HDAC2

2.98e-08734318241676
Pubmed

Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases.

HDAC3 HDAC1 HDAC2

2.98e-08734317956988
Pubmed

Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor.

HDAC3 HDAC1 HDAC2

2.98e-08734311022042
Pubmed

Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR.

HDAC3 HDAC1 HDAC2

2.98e-08734311804585
Pubmed

Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow.

HDAC3 HDAC1 HDAC2

2.98e-08734322308472
Pubmed

HDAC3 Is a Master Regulator of mTEC Development.

HDAC3 HDAC1 HDAC2

4.76e-08834327068467
Pubmed

ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain.

HDAC3 HDAC1 HDAC2

4.76e-08834311533236
Pubmed

Pleiotropic effects of p300-mediated acetylation on p68 and p72 RNA helicase.

HDAC3 HDAC1 HDAC2

4.76e-08834320663877
Pubmed

Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression.

HDAC3 HDAC1 HDAC2

4.76e-08834312032080
Pubmed

Transcription repressor activity of spleen tyrosine kinase mediates breast tumor suppression.

HDAC3 HDAC1 HDAC2

4.76e-08834316288017
Pubmed

Identification of a nuclear domain with deacetylase activity.

HDAC3 HDAC1 HDAC2

7.14e-08934310984530
Pubmed

The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor.

HDAC3 HDAC1 HDAC2

7.14e-08934311641275
Pubmed

PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells.

HDAC3 HDAC1 HDAC2

7.14e-08934316537907
Pubmed

The effects of trichostatin A on mRNA expression of chromatin structure-, DNA methylation-, and development-related genes in cloned mouse blastocysts.

HDAC3 HDAC1 HDAC2

7.14e-08934318241125
Pubmed

Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo.

HDAC3 HDAC1 HDAC2

7.14e-08934311466315
Pubmed

Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development.

HDAC3 HDAC1 HDAC2

7.14e-08934315367668
Pubmed

Histone deacetylase 10 regulates DNA mismatch repair and may involve the deacetylation of MutS homolog 2.

HDAC3 HDAC1 HDAC2

7.14e-08934326221039
Pubmed

The bZIP repressor proteins, c-Jun dimerization protein 2 and activating transcription factor 3, recruit multiple HDAC members to the ATF3 promoter.

HDAC3 HDAC1 HDAC2

7.14e-08934322989952
Pubmed

NFATc1 mediates HDAC-dependent transcriptional repression of osteocalcin expression during osteoblast differentiation.

HDAC3 HDAC1 HDAC2

7.14e-08934319463978
Pubmed

Proto-oncogene FBI-1 represses transcription of p21CIP1 by inhibition of transcription activation by p53 and Sp1.

HDAC3 HDAC1 HDAC2

7.14e-08934319244234
Pubmed

Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis.

HDAC3 HDAC1 HDAC2

1.02e-071034311923873
Pubmed

Class II histone deacetylases: versatile regulators.

HDAC3 HDAC1 HDAC2

1.02e-071034312711221
Pubmed

Histone Deacetylase 1 Is Essential for Rod Photoreceptor Differentiation by Regulating Acetylation at Histone H3 Lysine 9 and Histone H4 Lysine 12 in the Mouse Retina.

HDAC3 HDAC1 HDAC2

1.02e-071034328028172
Pubmed

Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells.

HDAC3 HDAC1 HDAC2

1.02e-071034315619633
Pubmed

Histone deacetylase 1 and p300 can directly associate with chromatin and compete for binding in a mutually exclusive manner.

HDAC3 HDAC1 HDAC2

1.87e-071234324722339
Pubmed

Transcriptional regulation by the repressor of estrogen receptor activity via recruitment of histone deacetylases.

HDAC3 HDAC1 HDAC2

1.87e-071234315140878
Pubmed

A molecular dissection of the repression circuitry of Ikaros.

HDAC3 HDAC1 HDAC2

3.08e-071434312015313
InteractionOVOL1 interactions

HDAC3 HDAC1 HDAC2

9.55e-0712343int:OVOL1
InteractionARID4A interactions

HDAC3 FRYL HDAC1 HDAC2

6.77e-0673344int:ARID4A
InteractionTKFC interactions

DEFA1 STING1 AGL HDAC2

1.77e-0593344int:TKFC
InteractionSAP30L interactions

HDAC3 HDAC1 HDAC2

2.31e-0533343int:SAP30L
InteractionC22orf31 interactions

HDAC1 HDAC2

2.75e-055342int:C22orf31
InteractionTNFSF10 interactions

HDAC3 HDAC1 HDAC2

2.77e-0535343int:TNFSF10
InteractionMAFK interactions

HDAC3 HDAC1 HDAC2

3.28e-0537343int:MAFK
InteractionNR2E1 interactions

HDAC3 HDAC1 HDAC2

3.55e-0538343int:NR2E1
InteractionDEFA3 interactions

DEFA1 DEFA3

4.13e-056342int:DEFA3
InteractionZNF521 interactions

HDAC3 HDAC1 HDAC2

4.48e-0541343int:ZNF521
InteractionJDP2 interactions

HDAC3 HDAC1 HDAC2

4.81e-0542343int:JDP2
InteractionSNAI3 interactions

HDAC1 HDAC2

7.69e-058342int:SNAI3
InteractionHR interactions

HDAC3 HDAC1 HDAC2

8.15e-0550343int:HR
InteractionPRDM4 interactions

HDAC3 HDAC1 HDAC2

9.16e-0552343int:PRDM4
InteractionNRP2 interactions

DEFA1 STING1 L1CAM

1.34e-0459343int:NRP2
InteractionINSM1 interactions

HDAC3 HDAC1

1.51e-0411342int:INSM1
InteractionSMYD1 interactions

HDAC3 HDAC1 HDAC2

1.55e-0462343int:SMYD1
InteractionSPI1 interactions

HDAC3 HDAC1 HDAC2

1.95e-0467343int:SPI1
InteractionDTX3L interactions

JAK2 STING1 HDAC2

2.04e-0468343int:DTX3L
InteractionTBX3 interactions

HDAC3 HDAC1 HDAC2

2.13e-0469343int:TBX3
InteractionH2AC1 interactions

HDAC3 HDAC1 HDAC2

2.32e-0471343int:H2AC1
InteractionAPPL1 interactions

HDAC3 AGL HDAC1 HDAC2

2.41e-04182344int:APPL1
InteractionCCDC71 interactions

FRYL HDAC1 HDAC2

2.42e-0472343int:CCDC71
InteractionBCL11B interactions

HDAC3 HDAC1 HDAC2

2.62e-0474343int:BCL11B
InteractionPPP4R1 interactions

HDAC3 CTNND1 HDAC1

2.84e-0476343int:PPP4R1
InteractionHDAC9 interactions

HDAC3 HDAC1 HDAC2

3.06e-0478343int:HDAC9
InteractionCBFA2T3 interactions

HDAC3 HDAC1 HDAC2

3.06e-0478343int:CBFA2T3
InteractionFRY interactions

FRYL STING1

3.27e-0416342int:FRY
InteractionCCN5 interactions

HDAC3 HDAC1

3.27e-0416342int:CCN5
InteractionMIER1 interactions

HDAC3 HDAC1 HDAC2

3.30e-0480343int:MIER1
InteractionNR2C1 interactions

HDAC3 HDAC1 HDAC2

3.81e-0484343int:NR2C1
Cytoband8p23.1

DEFA1 DEFA3

5.85e-031543428p23.1
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

HDAC3 HDAC1 HDAC2

8.21e-094243989
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

HDAC1 HDAC2

6.05e-0592421306
GeneFamilyPHD finger proteins|NuRD complex

HDAC1 HDAC2

1.11e-04122421305
GeneFamilyDefensins, alpha

DEFA1 DEFA3

1.11e-0412242502
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

HDAC1 HDAC2

1.11e-04122421243
GeneFamilyBasic leucine zipper proteins|BTB domain containing

BTBD6 BTBD3

1.35e-02134242861
CoexpressionAtlasbone marrow

DEFA1 DEFA3 RASGRP4 FCAR MMP9 SRGN

6.25e-06292346bone marrow
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Hpgd|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL6A1 RASGRP4 ACP7 MMP9 LRATD1

4.15e-081263459b04ca8a46cc30119baf6ef27711a0b2a6b4a0c9
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GDPD5 STING1 ATXN7 L1CAM

6.90e-061623446ffcf369d954c20ce036aa1d072cee4e205f728e
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GDPD5 STING1 ATXN7 L1CAM

6.90e-06162344bcbf7f80a2a1c80def795e345f16cf16e8b9d03b
ToppCellMonocytes-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

JAK2 FCAR SRGN

7.09e-0649343bf67f5dee042fd680c661db637fde715e48b14c5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Neutrophil|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RASGRP4 FCAR MMP9 SRGN

8.95e-06173344dfa56753319c92ae5b337793c4d6d5f70afce546
ToppCellwk_15-18-Hematologic-Myeloid-Myelocyte-like|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DEFA1 FCAR MMP9 SRGN

1.17e-0518534492b9ec18ff7c53a52b87e2c2012d0b719a7ad20a
ToppCellPBMC-Severe-Myeloid-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DEFA1 DEFA3 MMP9 SRGN

1.29e-05190344cb62ece5929896dfba30a4f563c6ba5a5712b71e
ToppCellPBMC-Severe-Myeloid-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DEFA1 DEFA3 MMP9 SRGN

1.29e-05190344fedd266198d294d8da8c9e217e5e0cb8b2e1b566
ToppCellCOVID-19_Severe-Myeloid_G|COVID-19_Severe / Disease group, lineage and cell class

DEFA1 DEFA3 MMP9 SRGN

1.29e-051903448a81cb90273c361e9fdfaa0a31806da253fa1388
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DEFA3 JAK2 CRYGD MMP9

1.35e-05192344072281344d58e85c9a290750b488d0c101f75d54
ToppCellCOVID_vent-Myeloid-Monocytic-Developing_Neutrophil|COVID_vent / Disease condition, Lineage, Cell class and subclass

DEFA1 DEFA3 FCAR MMP9

1.43e-05195344de23409b1b4146b8ae286850b829ec8dceed0117
ToppCellcontrol-Myeloid-Non-resident_Macrophage|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RASGRP4 FCAR MMP9 SRGN

1.46e-05196344646a8d47dddffdfd2d8a62245ea6cd49f9510a1a
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-neutrophil-promyelocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

DEFA1 CRYGD STING1 SRGN

1.49e-05197344cfc9decbfa9ebadafda8b620ec529d3fcdd15dcd
ToppCellCOVID-19_Severe-immature_Neutrophil|COVID-19_Severe / Disease condition and Cell class

DEFA1 DEFA3 MMP9 AGL

1.55e-05199344f82fa9d651e78f9ebbe6264e00a48c54b1786a69
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CCL|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RASGRP4 FCAR MMP9 SRGN

1.55e-0519934451be0e3a91d1f25454b56d55ef6342ef8e8df4e8
ToppCellCOVID-19_Severe-immature_Neutrophil-|COVID-19_Severe / Disease condition and Cell class

DEFA1 DEFA3 MMP9 AGL

1.55e-0519934442ea0c19c455bdb0ae89b428d09c333104c670dc
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DEFA1 DEFA3 MMP9

1.20e-04126343730fc6dc740613b55e40e85334fa30330aa81c3b
ToppCellControl-Myeloid_G-Neutrophil|Control / Disease group, lineage and cell class

DEFA1 DEFA3 MMP9

1.23e-04127343d4af23d621b546785a077c367c3a66c59749fc15
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DEFA1 DEFA3 MMP9

1.26e-041283439b3c57d559a5ed8d590dd89b64a57a3227d8c684
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DEFA1 DEFA3 MMP9

1.26e-0412834358639cfdc70ff6764adcc5c1ce9eba9d033b8209
ToppCellPBMC-Control-Myeloid-Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DEFA1 DEFA3 MMP9

1.29e-041293435578a9ef85706ab6a204ff31716e781ec3893b75
ToppCellPBMC-Control-Myeloid-Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DEFA1 DEFA3 MMP9

1.32e-04130343124f76067a2d4448ce06158a769d0d11b0297110
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DEFA1 DEFA3 MMP9

1.32e-04130343cd6d8d646345b01ff0f04f776330a05b82e63bc9
ToppCellPBMC-Mild-Myeloid-Neutrophil|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DEFA1 DEFA3 MMP9

1.35e-04131343fdec4e31ffeb02615ccb7097758a8218dd1f8c1c
ToppCellControl-Myeloid_G|Control / Disease group, lineage and cell class

DEFA1 DEFA3 MMP9

1.35e-04131343d5a53431f1f1b283fb9338b8561e6381f0227c62
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MMP9 AGL

1.41e-04133343f6e9a1301a3379847b215303a9b0c028841e2cc0
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MMP9 AGL

1.41e-04133343292ecfcadbaf15e0d34a3ab9bf511ab1065888bd
ToppCellCOVID-19_Mild-Myeloid_G|COVID-19_Mild / Disease group, lineage and cell class

DEFA1 DEFA3 MMP9

1.71e-04142343c8aeb747ed836197265d269aa131fae172b45aec
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP9 SRGN L1CAM

1.71e-04142343bf3537bec0eca9f90c00df9ba840c371f1c9856e
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DEFA1 DEFA3 MMP9

1.75e-041433434622c221b5d2d4cd4f37e4f81662e073924e1507
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DEFA1 DEFA3 MMP9

1.75e-041433439836a040a2ebcf6f05431e658a7b8fd566621452
ToppCellPBMC-Mild-Myeloid-Neutrophil|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

DEFA1 DEFA3 MMP9

1.75e-04143343974260c25dad599eea83a33e83117f7307b92a42
ToppCellMyeloid-E_(Neutrophils)|World / shred on cell class and cell subclass (v4)

RASGRP4 MMP9 SRGN

1.82e-041453436ae7dbc62116b4d0610fb55703679488e8da4733
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Cortical_neuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

TULP4 L1CAM HDAC2

1.94e-04148343a1269312903fc27830c1835dabf660c659a711be
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASGRP4 MMP9 SRGN

1.98e-041493432a2a5673ce4f376e7b25f2bc8127fb7e260f37af
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASGRP4 MMP9 SRGN

1.98e-04149343c9f02ec62a658a751e591699f9395fe597e22a2e
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP9 SRGN L1CAM

1.98e-04149343c9334f319a0c943268e54b6f0c9446736172c3a9
ToppCellMyeloid-Myeloid-E_(Neutrophils)|Myeloid / shred on cell class and cell subclass (v4)

RASGRP4 MMP9 SRGN

2.01e-041503431bffb8d86b737ac43be902d9468041aef3542f1f
ToppCellMonocytes-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

RASGRP4 FCAR SRGN

2.01e-04150343b580b06795973fec16ea6f7f5b6b9d580bf7fcf5
ToppCelldroplet-Lung-3m-Hematologic-myeloid-neutrophil-neutrophil|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 MMP9 SRGN

2.14e-04153343ce6e462ce4dbaf9d265f1f9e2f791efbba8c1dd0
ToppCelldroplet-Lung-3m-Hematologic-myeloid-neutrophil|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 MMP9 SRGN

2.14e-041533439dba38574908f31a1194b8a339868f5e4be1be71
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-lymphocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MMP9 SRGN

2.18e-04154343ad6cfd7fc02f4201863dc8e12e353395c86c5fdb
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP9 SRGN L1CAM

2.18e-04154343f92d83c5f8b532fe5624f1cd352632f543d96ea9
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GDPD5 ABCC10 BTBD3

2.22e-0415534351f6447945389649d99dcf7603b396195c631ead
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GDPD5 ABCC10 BTBD3

2.22e-0415534323dc71cab28094ca0ac4d2baf4e24871ed107781
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASGRP4 MMP9 SRGN

2.22e-041553433f31f3c37eb40d5467def8506e349fa4b4695833
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

JAK2 CTNND1 MYADML2

2.30e-04157343e9d0300361b06aec3c216f8af15f09e14b12a4da
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

JAK2 CTNND1 MYADML2

2.35e-04158343e9657d8960d499832f9f9b45b5a6f4388551b7e1
ToppCellfacs-MAT-Fat-18m-Myeloid-myeloid_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MMP9 SRGN

2.44e-04160343bd5fa7959bfe81011b8d798535b73ea1eee008b3
ToppCellnormal_Lymph_Node-T/NK_cells-CD8+/CD4+_Mixed_Th|normal_Lymph_Node / Location, Cell class and cell subclass

GDPD5 BTBD6 SRGN

2.53e-0416234312bd0b99aee13da60d0684a5e2a705824db1899c
ToppCellfacs-Liver-Non-hepatocytes-24m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MMP9 L1CAM

2.57e-04163343abec4389cd88252449f110fe95416d67424b403a
ToppCelldroplet-Spleen-nan-18m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MMP9 CNMD

2.57e-04163343bc37c5d9f48b16096d5313657563f3ec84028c8c
ToppCelldroplet-Fat-Scat-21m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 DEFB123 CNMD

2.67e-041653433f0c2486ea357d10dad0b703cf75cc29bdd5b5cf
ToppCellfacs-MAT-Fat-18m-Myeloid|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MMP9 SRGN

2.71e-041663439116be2805c34881debb999d8417e43832fcf2f2
ToppCellLAM-Myeloid-Mast|LAM / Condition, Lineage and Cell class

CRYGD ACP7 SRGN

2.71e-04166343e0ce973cc2a091b832c67b3b32dc153379daa2ef
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Neutrophil|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FCAR MMP9 SRGN

2.71e-041663436a65dff1333f39ec8c584e6df04b8c1e7f1c8946
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP|bone_marrow / Manually curated celltypes from each tissue

DEFA1 CRYGD CNMD

2.71e-041663439788486582cc2c5f28b9ea015e235732f9fefb1e
ToppCellfacs-MAT-Fat-18m-Myeloid-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MMP9 SRGN

2.71e-041663435c2667da79935f3d4b1edbfe7a10e7dbc2fa3ad0
ToppCelldroplet-Lung-18m-Hematologic-myeloid-neutrophil-neutrophil|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 MMP9 SRGN

2.81e-04168343b0376e3687fa85f091654196403eecedc219d0cd
ToppCelldroplet-Lung-18m-Hematologic-myeloid-neutrophil|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 MMP9 SRGN

2.81e-04168343937332580a522826b820e0b09080013f19f58479
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Spindle_Cell-1|TCGA-Uvea / Sample_Type by Project: Shred V9

GDPD5 COL6A1 EML3

2.81e-04168343b427746929bb40e3d1b5f1c40d302b792d6b32a5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RASGRP4 MMP9 SRGN

2.91e-04170343be2a34c70665d8d11332b1a70eda03d77cb7f7dd
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic-Basophil|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JAK2 SRGN L1CAM

2.91e-04170343bca78719c17355772ad6c53ee75e459faf1d089f
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JAK2 SRGN L1CAM

2.91e-0417034340d863554ec98ae43f76511c1112859688846613
ToppCelldroplet-Marrow-nan-24m-Hematologic-proerythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MMP9 SRGN

2.96e-04171343b3ea26d181f91ea07074f403e7dca9b6b671b1a2
ToppCelldroplet-Marrow-nan-21m-Hematologic-proerythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MMP9 SRGN

2.96e-04171343d6ae456e88ec49a8609a5e5e3af9f51921e66744
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Neutrophil|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RASGRP4 MMP9 SRGN

2.96e-04171343ef9397cec7f5c217d34583f26270af7ed7fbcebf
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRP4 FCAR SRGN

3.01e-04172343cf46810dd1072b6f2171e5d9530351ddc79a055b
ToppCellfacs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

JAK2 RASGRP4 SRGN

3.01e-04172343eaba10a4d4eaab42ad2e2da65ebb20b50edaf815
ToppCellwk_15-18-Hematologic-Myeloid-Mast|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CRYGD RASGRP4 SRGN

3.01e-04172343a7146c255031207e64682ef767884b11c96e0d59
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRYGD RASGRP4 SRGN

3.01e-041723432ab720a4c96073339a1f8b95ec7699682df98acf
ToppCelldroplet-Lung-3m-Hematologic-myeloid-Basophil/Mast_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

JAK2 SRGN L1CAM

3.06e-04173343b2c55084ef6dac0e329c2e65c24cfe0045859c30
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRYGD RASGRP4 SRGN

3.06e-04173343b9dc42d629d13e63aada5ae49ba0cbb0952c5fe9
ToppCelldroplet-Lung-3m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

JAK2 SRGN L1CAM

3.06e-04173343120dd20e8a71f9169a1596b6171df7aa0b96dd15
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Basophil|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP9 SRGN L1CAM

3.06e-041733432cba41c3d9d3076f703115d19729073a3ac3feb6
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP9 SRGN L1CAM

3.06e-0417334311d69a4ab4a87b8820cd3bd204de8c4124450a90
ToppCelldroplet-Marrow-nan-18m-Hematologic-proerythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MMP9 SRGN

3.06e-0417334303cee3d24bc433e91a867ce951589de64a0538af
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CTNND1 SRGN BTBD3

3.11e-04174343cb0109661e8c9ca04d67d33f2d926f0e649bf67d
ToppCellNS-control-d_0-4-Myeloid-Mast_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

A1BG RASGRP4 SRGN

3.11e-041743432d1f5c17b1551f32f49618ec1bf68eafbfd02ace
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRYGD RASGRP4 SRGN

3.11e-0417434336080fa12497faa752ff07ae52cd3864053eafef
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAK2 CHKB SRGN

3.11e-04174343ce9bdd02dc8eb45ba9c1481619c0089b465e6442
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Neutrophil|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RASGRP4 MMP9 SRGN

3.22e-04176343676839d07450b313222622e0ffd305c732cbad6d
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRYGD RASGRP4 SRGN

3.27e-041773434a222234ca6cf28a34205c4bd675cd49d92b5b2e
ToppCelldroplet-Marrow-nan-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MMP9 SRGN

3.27e-041773435d70fe2b0592362d664b3b4c84eb450ec2335957
ToppCelldroplet-Marrow-nan-18m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MMP9 SRGN

3.27e-0417734348bcf603ec9593eedd81f3831cf9fde89fad368f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Neutrophil|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FCAR MMP9 SRGN

3.27e-04177343ed44b1bf2ffae97f94e944d1b6060d5163eba6a6
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRYGD RASGRP4 SRGN

3.27e-0417734315553c7cd7826c80086daa76af4224f32dde53a6
ToppCelldroplet-Skin-nan-18m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 STING1 SRGN

3.33e-04178343e0769ad06f92423a3cb6c78a61da3ba5bd9b4eae
ToppCelldroplet-Skin-nan-18m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 STING1 SRGN

3.33e-0417834311c2ce093b7538518c8d4497dc5b0b4da22bf1a8
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-Mast_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRYGD RASGRP4 SRGN

3.33e-04178343c6704fcd21a9d2fe45679a1d998f04213b3bf224
ToppCelldroplet-Skin-nan-18m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 STING1 SRGN

3.33e-0417834312d5c6be6cfbf733e3cb02780606b3725eda7d2b
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DEFA1 DEFA3 CRYGD

3.44e-04180343f598bb9df0d784120847fada2d9a2a88b8b68cd1
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DEFA1 DEFA3 CRYGD

3.44e-04180343b4fa047f271c7b56940bdc85c912f50aa5b5ca82
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRP4 MMP9 SRGN

3.50e-0418134308bc6fe2a11d31a7e5e4a4552b04c0ebc2aefc59
ToppCellMonocytes-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

RASGRP4 FCAR SRGN

3.50e-04181343d8b98c3d9bef026a0a35948219027f27718ffbee
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FCAR MMP9 SRGN

3.50e-041813433457c1d431db4282be5a6243119e48960748ede7
ToppCellLPS_only-Myeloid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FCAR MMP9 SRGN

3.55e-04182343666ac86ee5f6fa9241ae8d80340743707e54b278
ToppCellcellseq2-Immune-Hematopoietic-Granulocytic-Neutrophil|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FCAR MMP9 SRGN

3.55e-041823431932d77491d6d46278f01fd70eb469ef1b356619
ToppCellcellseq2-Immune-Hematopoietic-Granulocytic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FCAR MMP9 SRGN

3.61e-04183343cfbf8539104cef9ca830ad4f6bb278746f7078f7
ToppCellPCW_05-06-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_neutrophils_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DEFA3 FCAR SRGN

3.61e-04183343aed12b743334f3813db0c70d4fe7df90e0673f54
DrugVorinostat

HDAC3 HDAC1 HDAC2

3.04e-085343DB02546
DrugAC1NRC7S

A1BG DEFA1 DEFA3 MMP9

3.60e-0823344CID005288867
DrugCI-994

HDAC3 HDAC1 HDAC2

3.62e-0710343CID000002746
Drug15-deoxy-delta(12,14)-prostaglandin J2

JAK2 HDAC3 MMP9 HDAC1 HDAC2

7.14e-07114345ctd:C097240
DrugFingolimod Hydrochloride

HDAC3 MMP9 HDAC1 HDAC2

1.34e-0655344ctd:D000068876
DrugAC1NV99J

HDAC3 HDAC1 HDAC2

1.68e-0616343CID005474719
Drugpolyphenon E

HDAC3 HDAC1 HDAC2

2.04e-0617343ctd:C472086
DrugRodeo

HDAC3 HDAC1 HDAC2

2.04e-0617343CID000038078
Drug2-methoxyethoxy)acetic acid

DEFA1 DEFA3

2.16e-062342CID000027642
Drugp-sulfobenzyl alcohol

DEFA1 DEFA3

2.16e-062342CID000441138
DrugPimelic Acids

HDAC3 HDAC1

2.16e-062342ctd:D010867
Drug1,2,5,6-tetramethylnaphthalene

DEFA1 DEFA3

2.16e-062342CID006427081
Drug1,4,5-trimethylnaphthalene

DEFA1 DEFA3

2.16e-062342CID000016478
DrugAC1L1EXH

HDAC3 HDAC1 HDAC2

2.44e-0618343CID000002992
DrugNSC3852

HDAC3 HDAC1 HDAC2

3.41e-0620343CID000019103
DrugAC1L1EA5

HDAC3 HDAC1 HDAC2

6.03e-0624343CID000002706
Drugtrapoxin B

HDAC3 HDAC1

6.49e-063342ctd:C067071
Drug4-ethylbenzoate

DEFA1 DEFA3

6.49e-063342CID000012086
DrugUF010 compound

HDAC3 HDAC1 HDAC2

6.84e-0625343ctd:C000602704
Drugtopanol A

DEFA1 DEFA3

1.30e-054342CID000015884
Drug4-fluorobenzoyl chloride

DEFA1 DEFA3

1.30e-054342CID000067879
Drugxenognosin B

DEFA1 DEFA3

1.30e-054342CID005280551
DrugAC1L3OZP

DEFA1 DEFA3

1.30e-054342CID000092862
Drugsperabillin A

DEFA1 DEFA3

1.30e-054342CID006441177
DrugAC1L1G8B

HDAC3 HDAC1 HDAC2

1.47e-0532343CID000003571
Drugtriglyme

LIPF DEFA1 DEFA3

1.47e-0532343CID000008189
DrugAC1OC6D1

HDAC3 HDAC1 L1CAM HDAC2

1.71e-05104344CID006368594
DrugAC1OAH4D

HDAC3 HDAC1 HDAC2

2.10e-0536343CID006857719
DrugAC1O5T5C

DEFA1 DEFA3

2.16e-055342CID006440182
Drugdipropylacetal

DEFA1 DEFA3

2.16e-055342CID000066929
Drug4-carbethoxyhexafluorobutyryl chloride

DEFA1 DEFA3

2.16e-055342CID000161251
Drugtanshinone

HDAC3 COL6A1 MMP9 HDAC1

2.64e-05116344ctd:C021751
DrugBT-B

HDAC3 BTBD6 CTNND1 HDAC1 HDAC2

2.87e-05243345CID000081462
Drugflufenacet

DEFA1 DEFA3

3.23e-056342CID000086429
Drugtestosterone acetate

DEFA1 DEFA3

3.23e-056342CID000092145
DrugAR-L57

DEFA1 DEFA3

3.23e-056342CID000156890
DrugTMSI

DEFA1 DEFA3

4.52e-057342CID000028925
Drug4-sulfobenzoate

DEFA1 DEFA3

4.52e-057342CID000069469
Drug4-amino-5-chloro-2-methoxybenzoate

HDAC3 HDAC2

4.52e-057342CID000081626
Drug3-bromopropionate

DEFA1 DEFA3

4.52e-057342CID000011553
DrugAC 695

HDAC3 SRGN HDAC2

4.72e-0547343CID000004885
DrugTaifun

DEFA1 DEFA3

6.03e-058342CID000047937
DrugAC1L2CQC

DEFA1 DEFA3

6.03e-058342CID000018756
Drug2,6-DMN

DEFA1 DEFA3

6.03e-058342CID000011387
Drugtraumatin

DEFA1 DEFA3

6.03e-058342CID005312889
DrugNSC-364372

HDAC3 CTNND1 MMP9 HDAC1 HDAC2 HPX

7.26e-05484346CID000435143
Drugmyxoxanthophyll

DEFA1 DEFA3

7.74e-059342CID005319993
Drugginsenoside Rh2

HDAC1 HDAC2

7.74e-059342ctd:C055305
DrugI82-2

DEFA1 DEFA3

7.74e-059342CID000007899
Drugdithiopyr

DEFA1 DEFA3

7.74e-059342CID000091757
DrugBuPdG

DEFA1 DEFA3

7.74e-059342CID003036311
Drugtrapoxin

HDAC3 HDAC1 HDAC2

8.88e-0558343CID000121875
DrugSNAG

HDAC3 HDAC1 HDAC2

9.34e-0559343CID000177324
DrugS 14297

HDAC3 HDAC2

9.67e-0510342CID000115007
Drug1-methylnaphthalene

DEFA1 DEFA3

9.67e-0510342CID000007002
DrugAC1Q4I4X

DEFA1 DEFA3

9.67e-0510342CID000122085
DrugN-methylpyrrolidine

DEFA1 DEFA3

9.67e-0510342CID000008454
Drug1,3-glyceryl dinitrate

DEFA1 DEFA3

9.67e-0510342CID000012200
Drugvorinostat

HDAC3 ATXN7 HDAC1 HDAC2 HPX

9.68e-05314345CID000005311
DrugDB08184

HDAC3 MMP9 HDAC1 HDAC2

1.09e-04167344CID009547945
DrugAC1L3UED

DEFA1 DEFA3

1.18e-0411342CID000122332
Drugbornane

DEFA1 DEFA3

1.18e-0411342CID000092108
DrugAC1L9IH9

HDAC3 HDAC2

1.18e-0411342CID000445730
Drugiodosulpride

HDAC3 HDAC2

1.42e-0412342CID000122245
Drugtetrahydronaphthalen-1-ol

HDAC3 HDAC2

1.42e-0412342CID000001240
DrugUh 232

HDAC3 HDAC2

1.42e-0412342CID000123696
DrugP 14

DEFA1 DEFA3

1.67e-0413342CID000056603
Drug4-tert-butylcatechol

DEFA1 DEFA3

1.67e-0413342CID000007381
Drugrhodotorulic acid

DEFA1 DEFA3

1.67e-0413342CID000029337
Drugdimethyltin

DEFA1 DEFA3

1.67e-0413342CID000031651
Drugfuculose

DEFA1 DEFA3

1.67e-0413342CID000000841
Drug2-propylpentanoic acid; Up 200; 500uM; HL60; HT_HG-U133A

COL6A1 CRYGD FCAR HPX

1.79e-041903446199_UP
DrugGo 6976

JAK2 CTNND1 MMP9

1.91e-0475343ctd:C081021
DrugAC1L9LVP

DEFA1 DEFA3

1.95e-0414342CID000448357
Drugdinitroglycerol

DEFA1 DEFA3

1.95e-0414342CID000079076
Drug6-.beta.-Naltrexol

DEFA1 DEFA3

1.95e-0414342CID000631219
DrugNifedipine [21829-25-4]; Up 200; 11.6uM; HL60; HT_HG-U133A

CTNND1 MMP9 EML3 CNMD

2.02e-041963441856_UP
DrugAltretamine [654-05-6]; Up 200; 19uM; HL60; HT_HG-U133A

GDPD5 FCAR CTNND1 CNMD

2.06e-041973443090_UP
Drugcis-4,7,10,13,16,19-Docosahexaenoic acid ethyl ester; Down 200; 100uM; MCF7; HT_HG-U133A_EA

JAK2 GDPD5 COL6A1 MMP9

2.10e-04198344881_DN
DrugThiethylperazine malate [52239-63-1]; Up 200; 6uM; MCF7; HT_HG-U133A

JAK2 COL6A1 SRGN HPX

2.14e-041993443576_UP
DrugThalidomide [50-35-1]; Up 200; 15.4uM; PC3; HT_HG-U133A

CRYGD MMP9 ATXN7 HPX

2.14e-041993442095_UP
DrugGabapentin [60142-96-3]; Down 200; 23.4uM; HL60; HT_HG-U133A

JAK2 GDPD5 FCAR CTNND1

2.14e-041993442731_DN
DrugFelbinac [5728-52-9]; Up 200; 18.8uM; MCF7; HT_HG-U133A

JAK2 GDPD5 COL6A1 FCAR

2.18e-042003445700_UP
Drugnafadotride

HDAC3 HDAC2

2.25e-0415342CID003408722
DrugAC1L2RBE

DEFA1 DEFA3

2.25e-0415342CID000101675
Drug13-HpOTrE

DEFA1 DEFA3

2.25e-0415342CID005282866
DrugTAM67

HDAC3 HDAC2

2.25e-0415342CID000005626
Drugpentafluorobenzoyl chloride

DEFA1 DEFA3

2.56e-0416342CID000075256
Drug3-hydroxy-9-methoxypterocarpan

DEFA1 DEFA3

2.56e-0416342CID000073067
Drug3-HPA

DEFA1 DEFA3

2.90e-0417342CID000013401
DrugS 15535

HDAC3 HDAC2

2.90e-0417342CID000132787
DrugPFPA

DEFA1 DEFA3

3.26e-0418342CID000067742
Drughexamethyldisiloxane

DEFA1 DEFA3

3.26e-0418342CID000024764
Drugnaphtho(1,2-b)furan-4,5-dione

JAK2 MMP9

3.26e-0418342ctd:C073873
Drugchondroitin sulfate

COL6A1 MMP9 SRGN L1CAM HPX

3.46e-04413345CID000024766
DrugAC1O4WK7

DEFA1 DEFA3

3.64e-0419342CID006420129
DrugGp54

DEFA1 DEFA3

3.64e-0419342CID003002999
Drugmetrizamide

COL6A1 MMP9

4.04e-0420342CID000035734
Drug3-methylcatechol

HDAC3 HDAC1 HDAC2

4.20e-0498343CID000000340
Drugtrifluoroacetamide

DEFA1 DEFA3

4.47e-0421342CID000067717
Diseasepulmonary hypertension (is_marker_for)

HDAC3 MMP9 HDAC1 HDAC2

6.91e-0764324DOID:6432 (is_marker_for)
Diseasetoll-like receptor 2 measurement

ABCC10 HPX

6.83e-064322EFO_0020777
Diseasepulmonary emphysema (biomarker_via_orthology)

MMP9 HDAC2

1.70e-056322DOID:9675 (biomarker_via_orthology)
Diseasecolorectal cancer (is_marker_for)

HDAC3 MMP9 HDAC1 L1CAM

2.47e-05157324DOID:9256 (is_marker_for)
Diseasepancreatic ductal carcinoma (is_marker_for)

MMP9 HDAC1 L1CAM

4.00e-0561323DOID:3587 (is_marker_for)
Diseasealopecia areata (is_marker_for)

HDAC1 HDAC2

5.10e-0510322DOID:986 (is_marker_for)
Diseasetype 1 diabetes mellitus (is_marker_for)

HDAC3 HDAC1 HDAC2

6.57e-0572323DOID:9744 (is_marker_for)
Diseasepulmonary hypertension (biomarker_via_orthology)

CTNND1 MMP9 HDAC1

8.99e-0580323DOID:6432 (biomarker_via_orthology)
Diseasethrombosis (is_implicated_in)

JAK2 MMP9

1.19e-0415322DOID:0060903 (is_implicated_in)
Diseaseendometriosis (biomarker_via_orthology)

MMP9 HDAC2

1.35e-0416322DOID:289 (biomarker_via_orthology)
Diseaseglaucoma (is_marker_for)

MMP9 HDAC1

2.14e-0420322DOID:1686 (is_marker_for)
Diseasetemporal lobe epilepsy (is_marker_for)

MMP9 HDAC2

2.14e-0420322DOID:3328 (is_marker_for)
Diseaseprostate carcinoma (is_marker_for)

HDAC3 HDAC2

2.84e-0423322DOID:10286 (is_marker_for)
DiseaseSquamous cell carcinoma

MMP9 HDAC1 HDAC2

3.29e-04124323C0007137
Diseasecolon adenocarcinoma (is_marker_for)

JAK2 MMP9

3.37e-0425322DOID:234 (is_marker_for)
Diseaseovarian carcinoma (is_marker_for)

HDAC3 L1CAM

4.23e-0428322DOID:4001 (is_marker_for)
Diseasechronic obstructive pulmonary disease (biomarker_via_orthology)

MMP9 HDAC2

4.23e-0428322DOID:3083 (biomarker_via_orthology)
Diseasestomach cancer (is_marker_for)

JAK2 MMP9 HDAC2

4.89e-04142323DOID:10534 (is_marker_for)
DiseaseChronic Obstructive Airway Disease

MMP9 HDAC2

5.89e-0433322C0024117
DiseaseChronic Airflow Obstruction

MMP9 HDAC2

5.89e-0433322C1527303
Diseaseacute lymphoblastic leukemia (is_marker_for)

HDAC1 HDAC2

6.25e-0434322DOID:9952 (is_marker_for)
Diseaseendometrial carcinoma (is_marker_for)

HDAC3 MMP9

6.25e-0434322DOID:2871 (is_marker_for)
Diseaseneutrophil measurement

DEFA1 DEFA3 SRGN

9.26e-04177323EFO_0803548
DiseaseCalcinosis

JAK2 MMP9

9.55e-0442322C0006663
DiseaseMicrocalcification

JAK2 MMP9

9.55e-0442322C0521174
DiseaseTumoral calcinosis

JAK2 MMP9

9.55e-0442322C0263628
Diseasecervix uteri carcinoma in situ (is_marker_for)

HDAC1 HDAC2

9.55e-0442322DOID:8991 (is_marker_for)
Diseaseglioblastoma (is_marker_for)

MMP9 L1CAM

1.05e-0344322DOID:3068 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
SSAYRSNQWRYRGRC

BTBD6

396

Q96KE9
CAYRSNQWRYRGRCD

BTBD3

381

Q9Y2F9
ERRAYQWCREYLGGA

CHKB

46

Q9Y259
PRWYCSGSNRAYRHG

JAK2

121

O60674
QYVYRCGSAQGWSRR

ACP7

106

Q6ZNF0
GPQHAGNYRCRYRSW

A1BG

461

P04217
GRSDGYRWCATTANY

MMP9

306

P14780
ARLWRALYGAFGRCY

ABCC10

271

Q5T3U5
SRYGRYVATQWCVAV

MYADML2

186

A6NDP7
GGYTIRNVARCWTYE

HDAC1

301

Q13547
NVSGIYRCYGWYNRS

FCAR

186

P24071
GNSRGNTWARRNLYY

LIPF

116

P07098
YWAVDRCYTGSGRVA

FRYL

1171

O94915
NNYARYRRTWAGCAG

RASGRP4

331

Q8TDF6
AANVGRVVNSWYRYR

LRATD1

171

Q96KN4
RGYNVTYWREGSQRK

L1CAM

846

P32004
GIYGCRWKRYQRSHD

GDPD5

21

Q8WTR4
RGYYVFDSRWNRLRC

ATXN7

531

O15265
GGYTVRNVARCWTYE

HDAC3

296

O15379
YRRYQDWGATNARVG

CRYGD

151

P07320
GERRYGTCIYQGRLW

DEFA1

76

P59665
GERRYGTCIYQGRLW

DEFA3

76

P59666
RYYRCDRNLVWNAGA

COL6A1

76

P12109
DWVYGYRGRDSRSNL

EML3

251

Q32P44
GTQRCWNLYGKCRYR

DEFB123

21

Q8N688
GGGYTIRNVARCWTY

HDAC2

301

Q92769
LCAGRWTYGRYIRSA

CTNND1

691

O60716
GNCSSALRWLGRYYC

HPX

186

P02790
RYRGSYWRTVRACLG

STING1

76

Q86WV6
WSVQYRYDGVGRRAS

TENM2

2296

Q9NT68
WPYNYQGCRSACRVI

CNMD

306

O75829
CRRRYYEEGWLATGN

TULP4

36

Q9NRJ4
QGYPTRRARYQWVRC

SRGN

26

P10124
GEGIYARYNCRDAVW

AGL

1141

P35573