Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptidase activity

ADAMTS12 ADAMTS18 KLK10 PCSK4 AGBL1 USP17L8

7.41e-04654346GO:0008233
GeneOntologyMolecularFunctionABC-type transporter activity

ABCG1 ABCA13

3.15e-0349342GO:0140359
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCG1 ANO8

3.41e-0351342GO:0140303
DomainIPNS-like

ASPHD2 ASPHD1

9.64e-063342IPR027443
DomainAsp_Arg_Hydrox

ASPHD2 ASPHD1

9.64e-063342PF05118
DomainAsp/Arg/Pro-Hydrxlase

ASPHD2 ASPHD1

9.64e-063342IPR007803
Domain-

ASPHD2 ASPHD1

9.64e-0633422.60.120.330
DomainFurin_repeat

FRAS1 PCSK4

4.83e-0418342IPR006212
DomainFU

FRAS1 PCSK4

4.83e-0418342SM00261
DomainPLAC

ADAMTS12 ADAMTS18

5.39e-0419342IPR010909
DomainPLAC

ADAMTS12 ADAMTS18

5.39e-0419342PS50900
DomainADAM_spacer1

ADAMTS12 ADAMTS18

7.95e-0423342IPR010294
DomainADAM_spacer1

ADAMTS12 ADAMTS18

7.95e-0423342PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS12 ADAMTS18

8.66e-0424342IPR013273
DomainPeptidase_M12B_N

ADAMTS12 ADAMTS18

2.29e-0339342IPR002870
DomainPep_M12B_propep

ADAMTS12 ADAMTS18

2.29e-0339342PF01562
DomainDISINTEGRIN_1

ADAMTS12 ADAMTS18

2.40e-0340342PS00427
DomainADAM_MEPRO

ADAMTS12 ADAMTS18

2.40e-0340342PS50215
DomainDISINTEGRIN_2

ADAMTS12 ADAMTS18

2.40e-0340342PS50214
DomainReprolysin

ADAMTS12 ADAMTS18

2.40e-0340342PF01421
DomainPeptidase_M12B

ADAMTS12 ADAMTS18

2.40e-0340342IPR001590
DomainCYSTEINE_SWITCH

ADAMTS12 ADAMTS18

2.52e-0341342PS00546
DomainDisintegrin_dom

ADAMTS12 ADAMTS18

2.52e-0341342IPR001762
DomainPept_M10_metallopeptidase

ADAMTS12 ADAMTS18

2.77e-0343342IPR001818
DomainABC_TRANSPORTER_2

ABCG1 ABCA13

3.44e-0348342PS50893
DomainABC_tran

ABCG1 ABCA13

3.44e-0348342PF00005
DomainABC_TRANSPORTER_1

ABCG1 ABCA13

3.59e-0349342PS00211
DomainABC_transporter-like

ABCG1 ABCA13

3.73e-0350342IPR003439
DomainTSP_1

ADAMTS12 ADAMTS18

5.86e-0363342PF00090
DomainTSP1

ADAMTS12 ADAMTS18

6.23e-0365342SM00209
DomainTSP1_rpt

ADAMTS12 ADAMTS18

6.23e-0365342IPR000884
DomainTSP1

ADAMTS12 ADAMTS18

6.23e-0365342PS50092
Pubmed

Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.

ADAMTS12 ADAMTS18

6.08e-051234225770910
Pubmed

Effect of expression alteration in flanking genes on phenotypes of St8sia2-deficient mice.

RGMA AGBL1

1.41e-041834231541165
Pubmed

A global genomic transcriptional code associated with CNS-expressed genes.

SNPH ITGA2 FBXO3 USH2A

2.56e-0431834416919269
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

ADAMTS18 SF3B1 DDX50 ABCA13

4.14e-0436134426167880
Pubmed

Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans.

LYPD1 TACR1

7.07e-044034233238113
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS12 ADAMTS18

2.17e-041921250
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Slco2a1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RGMA ADAMTS18 FRAS1 LYPD1

3.56e-061333549d7a08170d38ae9b2ff10a0fa505aeb3aae2824d
ToppCellwk_15-18-Epithelial-Proximal_epithelial-SMG_basal_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADAMTS18 XDH KLK10 ITGA2

1.08e-05176354045b12c90f7dd49a9778dadcdf8f18125b380531
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ITGA2 AGBL1 ABCA13 KCNV2

1.20e-05181354576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ITGA2 AGBL1 ABCA13 KCNV2

1.34e-05186354acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FRAS1 KLK10 ITGA2 KCNV2

1.65e-05196354c5adab88140a465698abcbedc6505a43cae7bfd1
ToppCellBasal_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 LYPD1 KLK10 ITGA2

1.65e-051963543b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Basal_1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

FRAS1 LYPD1 KLK10 ITGA2

1.68e-051973542701864e49878c5f323f5133e2c4b0a5a7fff7f5
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FRAS1 LYPD1 KLK10 ITGA2

1.68e-05197354751f19b00f92e1334f653b870d3f7c0c149ff41a
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FRAS1 KLK10 ITGA2 KCNV2

1.68e-05197354de772bd2b4cda843777ac879b1087e6444199dfb
ToppCellBasal_cells|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 LYPD1 KLK10 ITGA2

1.68e-0519735424360b660000bdfb999d58fbf4e29585a97e1785
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FRAS1 LYPD1 KLK10 ITGA2

1.68e-0519735458d809ccb8cc4b1e76acf0b8f996cd0e2637290c
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS12 FRAS1 ITGA2 PTGIR

1.78e-052003548c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

ADAMTS12 FRAS1 ITGA2 PTGIR

1.78e-05200354aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS12 FRAS1 ITGA2 PTGIR

1.78e-0520035434f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ADAMTS12 FRAS1 ITGA2 PTGIR

1.78e-05200354a510deaada669e690329183e18df02870bd204b3
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAMTS12 FRAS1 ITGA2 PTGIR

1.78e-05200354dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RGMA ADAMTS18 FRAS1

1.58e-04134353cb676d5bbc468bd3ce1b6712d41c986ee9221ac5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 USH2A PCSK4

1.79e-041403535e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CMPK2 ABCG1 SLC12A7

1.91e-04143353ce045ec7c311a1797ae562bec114f9e90604d063
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 USH2A ABCA13

1.99e-0414535396712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PLCD3 ABCG1 SLC12A7

2.03e-04146353bb7bf20245d93c8812920dd0debbf1ed00add378
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

USH2A AGBL1 ABCA13

2.03e-04146353c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYPD1 PTGIR KCNV2

2.11e-04148353dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CMPK2 LYPD1 LRRTM2

2.24e-04151353cba0939a6dd3519f6890695f5b237266ca1a7941
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CMPK2 LYPD1 LRRTM2

2.24e-04151353a937e3e5a63bfeb37d2cabb3177760ec583dbf11
ToppCellPBMC-Control-cDC_8|Control / Compartment, Disease Groups and Clusters

LYPD1 NR1I3 LRRTM2

2.33e-04153353db1a6914f2033fb0748e0523cffe5d6dc4e901be
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_CCDC184|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LYPD1 KLK10 USP17L8

2.42e-041553530d7410092b2e8bab7aa9181b9780b9331e483b17
ToppCellBasal_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

RGMA FRAS1 KLK10

2.42e-0415535330accc72a6a914ae0c4d52b373ea1c9a98efbf22
ToppCellPND07-28-samps-Mesenchymal-Mesothelial-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CMPK2 FRAS1 PCSK4

2.47e-04156353605d95a900e1443d3f6aae163ef2e893d3293203
ToppCellPND07-28-samps-Mesenchymal-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CMPK2 FRAS1 PCSK4

2.47e-04156353574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

LYPD1 KLK10 ITGA2

2.51e-04157353dd08dc19d434e94a194076c462ee273c682abf55
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCD3 SNPH ITGA2

2.51e-04157353fc127e7720649e746f3d3f5c2e9e63784767106a
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

LYPD1 KLK10 ITGA2

2.51e-0415735370fd6c46db4250c7de5c4686a9500689402737f6
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCD3 SNPH ITGA2

2.51e-0415735366a191cef4aa00811bb04462310d012610006f85
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 USH2A KCNV2

2.66e-04160353c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 USH2A KCNV2

2.66e-0416035325c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRAS1 USH2A ABCA13

2.76e-04162353bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellAdult-Epithelial-lung_goblet_cell-D175|Adult / Lineage, Cell type, age group and donor

TACR1 ABCA13 KCNV2

2.86e-041643536e6aedb61f8e195d52e028fdda750a29bb14e57e
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

RGMA XDH FRAS1

2.91e-04165353f6887c64af0f26e33316bc5587487e24d76ece2a
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|368C / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 KLK10 ASPHD1

2.96e-041663534d63c758d46e73311b864148c646bf081498dee7
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|368C / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 KLK10 ASPHD1

2.96e-041663534160ccf9291072a6e2782f9ad141bc9a9747f3ad
ToppCellFetal_29-31_weeks-Epithelial-basal_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FRAS1 ITGA2 ABCA13

3.07e-041683536521bead9789d626b86cbd08692c621c5a5aef33
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 KLK10 ASPHD1

3.07e-04168353e870d2e69316406f45112ed0bf324b24f902a99e
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SNPH SLC12A7 ABCA13

3.07e-041683538f0c4dfad9f6fed9dcc31795abfe77758ceb46a1
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS12 ASPHD1 PTGIR

3.07e-04168353a8958b94ffc3423d56c250796dd253884b46f9d9
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 KLK10 ASPHD1

3.07e-04168353403aba73a0f9ffb32252288d075fad8a588ca440
ToppCellFetal_29-31_weeks-Epithelial-basal_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FRAS1 ITGA2 ABCA13

3.12e-04169353c3ee781735a9288ce1822b230d39bb91c1415589
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TACR1 KLK10 ABCA13

3.12e-0416935308ac28c5ad8f5c5f9f54af341bf39e8f9417636e
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 USH2A ABCA13

3.12e-0416935312bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TACR1 KLK10 ABCA13

3.12e-04169353e5abd41db1e6724ad900e37658fa063b8e522908
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

FRAS1 ITGA2 ABCA13

3.23e-041713533965ced4be6db14265a90673502fceee425837ca
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|367C / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 KLK10 ASPHD1

3.34e-04173353e05cddf5bf63cf419343ff229453327519765be8
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|367C / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 KLK10 ASPHD1

3.34e-0417335374ad5ed33821b8816c9c8e67c50ee4496ba18e2f
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

FRAS1 TACR1 KLK10

3.40e-041743537d2f802f493f19a068e097b2909a9000e2160266
ToppCell10x_5'_v1-Neoplastic-Differentiated-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GBE1 LYPD1 GDF1

3.45e-041753533c3cbaeec6ef2f61e6b177c95b999752c2d83ddb
ToppCell10x_5'_v1-Neoplastic-Differentiated-like-MES-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GBE1 LYPD1 GDF1

3.45e-041753532dcb5145835c3872d0f92f3ece23730cf65487bd
ToppCell10x_5'_v1-Neoplastic|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GBE1 LYPD1 GDF1

3.45e-04175353379f595be2273f662064c920d195a30491aa88d6
ToppCellwk_20-22-Hematologic_Lymphocytic-B-Pro-B/Pre-B_transition|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ABCG1 SLC8B1 SF3B1

3.45e-04175353f86d2d212f8314b2410d5d84ef092b0b38607ea4
ToppCellMonocytes-IFN-activated_Monocytes|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CMPK2 ITGA2 USH2A

3.51e-041763536a4b403ee3e4dc4f23fbd7a154011e41fd429a9e
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XDH ABCA13 PTGIR

3.57e-04177353065bebd22031f143e90a407f952b444a3f8818c7
ToppCell10x_5'_v1-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GBE1 LYPD1 GDF1

3.57e-04177353f7a2e6b5e82f0565f8030696944f33c544233b94
ToppCellfacs-Marrow-Granulocytes-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XDH ABCA13 PTGIR

3.57e-04177353eb304f20aab075bd17aa3aef819386c0e1a235bd
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLCD3 KLK10 SLC12A7

3.57e-04177353d68132e145bd413404fdbe215b5dbe520e756e50
ToppCell10x_5'_v1-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GBE1 LYPD1 GDF1

3.57e-04177353ef02ee75db36a92dda889efb6fad1193efbc4be4
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PLCD3 KLK10 ITGA2

3.63e-041783539a3ef66814dfca7b37024e7f79e86ea8c72ae10f
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PLCD3 KLK10 ITGA2

3.63e-0417835319b5432aa1d7f616d58a106543c18cf2d7ca840c
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS12 RGMA AGBL1

3.63e-0417835309a215a0d6e98e4bb920cabda12af08ff4de3c98
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLCD3 KLK10 ITGA2

3.63e-04178353b413a634283550fa224db7d0d05956e3f64694a1
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLCD3 KLK10 ITGA2

3.63e-0417835349a2271718637522f74334068d252963ee13b1ce
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-1|TCGA-Liver / Sample_Type by Project: Shred V9

ADAMTS12 PLCD3 FRAS1

3.63e-0417835351c59dabf2d7aef1b1964f6f766d5ec07ef90f5a
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ASPHD1 GDF1 PTGIR

3.63e-04178353aa9f68a66e292f331faef881bbd0d028f0f2b0c5
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 TACR1 ITGA2

3.69e-0417935304ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_Erythro-Mega|lymph-node_spleen / Manually curated celltypes from each tissue

ASPHD2 PCSK4 ABCA13

3.69e-04179353957c08ad4b46eb4cc1717c45056fc3db50015fdc
ToppCell390C-Fibroblasts-Fibroblast-G|390C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS12 FRAS1 PTGIR

3.75e-04180353137fc14859c89e1ecd98bee388bb58c04b835847
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

XDH FRAS1 KLK10

3.75e-04180353b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell390C-Fibroblasts-Fibroblast-G-|390C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS12 FRAS1 PTGIR

3.75e-04180353cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCell5'-Adult-LargeIntestine-Mesenchymal-mesothelial_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS18 FRAS1 ASPHD1

3.81e-0418135365eaa9bc1022bcf0c5f0f92c07a2cbbf11f9b59c
ToppCell18-Airway-Epithelial-Submucosal_gland_basal|Airway / Age, Tissue, Lineage and Cell class

ADAMTS18 XDH ITGA2

3.81e-0418135333938e6521712058312879f84f4ae381c2bfc379
ToppCell5'-Adult-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(PRG4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS18 FRAS1 ASPHD1

3.81e-04181353eaac7d58117eddfff06b25521efc431c1351d592
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

XDH FRAS1 KLK10

3.87e-04182353215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 USH2A ABCA13

4.00e-04184353ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 USH2A ABCA13

4.00e-041843532cbed6462fea2622871bb7e49b0df3d984239281
ToppCellCV-Moderate-4|CV / Virus stimulation, Condition and Cluster

GBE1 ITGA2 ASPHD1

4.00e-0418435390f5b447064743246b09a6c47bf561efafa15e1f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 USH2A ABCA13

4.00e-041843532b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCV-Moderate-4|Moderate / Virus stimulation, Condition and Cluster

GBE1 ITGA2 ASPHD1

4.06e-041853534a3ce0c603c2ffe11f0f00775b6af4f6d9a6070a
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLCD3 RGMA SLC8B1

4.06e-0418535387151ab95530e70d61328b336518df58db584acb
ToppCellCD8+_Memory_T_cell-CV-4|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

GBE1 ITGA2 ASPHD1

4.19e-041873539c2fc2f259fa7d3a65fb99c295ac378e03d9aa6c
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Striatum / BrainAtlas - Mouse McCarroll V32

FRAS1 LYPD1 ASPHD1

4.26e-04188353e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CMPK2 ABCG1 PTGIR

4.26e-041883532c4e791df69a9df29922f9117e5cac7787c129ce
ToppCellSevere_COVID-19-Epithelial-undefined_Epi|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

PLCD3 KLK10 ITGA2

4.33e-041893538cbd35320c7e7ff013ef0c0f13f8d875db1c53cd
ToppCell15-Airway-Epithelial-Basal_cell|Airway / Age, Tissue, Lineage and Cell class

FRAS1 KLK10 ITGA2

4.33e-04189353f128c2fc37f232d193de18a922c47fdd70e1982d
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

ADAMTS12 FRAS1 ITGA2

4.39e-0419035371e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

TACR1 KLK10 ABCA13

4.39e-0419035351ca9ef4df3220487152fcf684147730637c7cc1
ToppCellBL-critical-LOC-Epithelial-Squamous|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

XDH KLK10 ITGA2

4.46e-041913533f9b8c4fb72ae6f3167b187e6715c4dcb3159f98
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

XDH FRAS1 KLK10

4.46e-0419135323776c7302cead3881b39127398f3b3e0d27885e
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

XDH KLK10 ITGA2

4.46e-04191353fbd8d337b4444fba8527a614e4a8bfb516ce0f66
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

XDH KLK10 ABCA13

4.46e-04191353529068029fb461df766135576dd0d8b5980f9bc0
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAMTS12 FRAS1 ITGA2

4.46e-041913536688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAMTS12 FRAS1 ITGA2

4.53e-0419235399ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

ADAMTS12 FRAS1 ITGA2

4.53e-0419235362904f94dfce430456f05066522cbf9bd29f4d7e
Drugpentafluorobenzoic acid

ITGA2 FBXO3

6.88e-063352CID000011770
Drughexylamine

GBE1 XDH PTGIR

7.48e-0625353CID000008102
Drug8-bromoxanthine

XDH ITGA2

1.37e-054352CID000025198
Drugoxomolybdenum

XDH ITGA2

2.29e-055352CID000139765
Drugbenzylthiourea

TACR1 ITGA2

3.43e-056352CID000737375
DrugD-4-acetylphe

TACR1 ITGA2

1.03e-0410352CID002763150
Drugmethylglucamine

SLC8B1 ITGA2 PTGIR

1.18e-0462353CID000004049
Drug1-hexene

LYPD1 ITGA2

2.07e-0414352CID000011597
Drug2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A

ABCG1 LYPD1 SLC8B1 ASPHD1

2.09e-041923541634_UP
Drug2-naphthylalanine amide

TACR1 ITGA2

2.38e-0415352CID000098159
DrugPropafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; PC3; HT_HG-U133A

XDH TACR1 ITGA2 ASPHD1

2.40e-041993546336_UP
DrugIsosorbide dinitrate [87-33-2]; Up 200; 17uM; MCF7; HT_HG-U133A

TACR1 KLK10 SNPH SLC8B1

2.44e-042003546038_UP
DrugHBED

XDH ITGA2

2.72e-0416352CID000037336
Drugdesmethoxyverapamil

TACR1 PTGIR

3.08e-0417352CID000065832
Drugpentafluorobenzyl bromide

ITGA2 FBXO3

3.08e-0417352CID000074484
Drugalaninamide

TACR1 PCSK4

3.08e-0417352CID000350287
DrugSupramid

RGMA ABCG1

3.08e-0417352CID000005326
DrugAC1L1IMV

ITGA2 PTGIR ICAM3

3.12e-0486353CID000004646
Drug1,2-benzenedithiol

XDH ITGA2

3.86e-0419352CID000069370
DrugNpc 17731

TACR1 PTGIR

3.86e-0419352CID003081308
DrugDuP-697

TACR1 PTGIR

4.29e-0420352CID000003177
DrugHgBr2

RGMA ITGA2

5.20e-0422352CID000024612
DrugAC1O44ID

ITGA2 PTGIR

5.69e-0423352CID006324632
DrugN1-methylnicotinamide

XDH PTGIR

5.69e-0423352CID000000457
DrugCID439354

GBE1 ICAM3

6.74e-0425352CID000439354
DrugDETCA

XDH ITGA2

6.74e-0425352CID000151422
DrugAC1NRBOH

RGMA ITGA2

8.46e-0428352CID005288550
DrugAC1Q5SG4

RGMA XDH ITGA2

8.46e-04121353CID000001129
Drugkadsurenone

ITGA2 PTGIR

9.08e-0429352CID000122159
Drugmaya

ITGA2 FBXO3

1.04e-0331352CID000063022
DrugSA446

KLK10 PTGIR

1.04e-0331352CID000071244
Drugaurin

LYPD1 ITGA2

1.11e-0332352CID000005100
DrugCH2OH

ITGA2 PTGIR

1.18e-0333352CID000137654
DrugRhodium

SNPH ITGA2

1.25e-0334352CID000023948
DrugNSC344479

XDH PCSK4

1.25e-0334352CID000023850
Drug1H-pyrazol

XDH ITGA2 PTGIR

1.32e-03141353CID000001048
Drugbimatoprost

RGMA PTGIR

1.32e-0335352CID005311027
Drugchlorpheniramine

TACR1 PTGIR

1.48e-0337352CID000002725
DrugL-365,260

RGMA TACR1

1.48e-0337352CID000104929
DiseaseHeart Diseases

XDH PTGIR

1.29e-0346342C0018799
Diseasecholestasis (biomarker_via_orthology)

XDH NR1I3

1.46e-0349342DOID:13580 (biomarker_via_orthology)
Diseasefemoral neck bone mineral density

PDXDC1 RGMA ADAMTS18

1.48e-03196343EFO_0007785
DiseaseDisorder of eye

FRAS1 USH2A KCNV2

1.86e-03212343C0015397
Diseasemetabolite measurement, diet measurement

PDXDC1 PDXDC2P

3.05e-0371342EFO_0004725, EFO_0008111
Diseasenucleotide measurement

TACR1 ITGA2

3.22e-0373342EFO_0010513
DiseaseMechanical Allodynia

TACR1 ITGA2

4.23e-0384342C2936719
DiseaseAllodynia

TACR1 ITGA2

4.23e-0384342C0458247
DiseaseHyperalgesia, Secondary

TACR1 ITGA2

4.23e-0384342C0751212
DiseaseHyperalgesia, Primary

TACR1 ITGA2

4.23e-0384342C0751211
DiseaseHyperalgesia, Thermal

TACR1 ITGA2

4.23e-0384342C0751214
DiseaseTactile Allodynia

TACR1 ITGA2

4.23e-0384342C0751213

Protein segments in the cluster

PeptideGeneStartEntry
VCNLVPYLRDLGLNC

ABCG1

301

P45844
PQFCLGQGLVELCYN

ABCA13

4616

Q86UQ4
AQLLNFGALCYGRQP

ADAMTS12

16

P58397
LFCPGSSRIYQLCNI

ADAMTS18

626

Q8TE60
GCNQGPYQCTQRLLE

AGBL1

991

Q96MI9
CYLIGQCGQLQRLFP

ANO8

821

Q9HCE9
CLQTQNFLCGPLRYT

NR1I3

211

Q14994
IIINGYGQCKCQQLP

LRRTM2

496

O43300
LGFYQAGSLCLACQP

FRAS1

456

Q86XX4
APGCYQLLLYQAGRC

ASPHD1

246

Q5U4P2
IAPRGFLANYCQGQC

GDF1

286

P27539
QRQGLKYCLPLTFCI

FBXO3

186

Q9UK99
QACDGPAYILGQLCL

PCSK4

606

Q6UW60
LGQYLCNQLGLPFPC

PDXDC1

186

Q6P996
LGQYLCNQLGLPFPC

PDXDC2P

186

Q6P474
QGILNCCLAYNVGLP

ITGA2

21

P17301
LQCQARGNPYPELRC

ICAM3

421

P32942
FYLVNQGVCVPRNCR

ASPHD2

231

Q6ICH7
QLLRLLCYCPGGQAG

CMPK2

111

Q5EBM0
CNVLPRIKGLGYNCI

GBE1

221

Q04446
GICICFYQPRERGQL

DDX50

486

Q9BQ39
CGLFLLPGFALQIQC

LYPD1

11

Q8N2G4
FIGVYLPCLQNILGV

SLC12A7

121

Q9Y666
PLQCFQLSRVYGFCL

SLC8B1

546

Q6J4K2
RQGRRCNQCQPGFYI

USH2A

926

O75445
NPIIYCCLNDRFRLG

TACR1

301

P25103
GFTLRQCYQQVGCLL

KCNV2

401

Q8TDN2
GQPIYNISSLLRGCC

SNPH

451

O15079
GLYLCLRGCPLNQQI

RGMA

311

Q96B86
CALPLLGLGQHQQYC

PTGIR

151

P43119
NGQCGYVLKPACLRQ

PLCD3

631

Q8N3E9
IGPCRMLQYCLQGLF

SF3B1

1241

O75533
NLCRCTGYRPILQGF

XDH

146

P47989
LNGENAYPCGLCLQR

USP17L8

246

P0C7I0
LQLPYRCAQPGDQCQ

KLK10

156

O43240