Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	kinase activity	CDK9 CDK16 MET CERK CMPK1 IGF2R RIPK1 PIK3R1 CSNK2A1 BAZ1B ATM GSK3B EPHA5	6.51e-06	764	77	13	GO:0016301
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	CDK9 CDK16 MET CERK IGF2R RIPK1 PIK3R1 CSNK2A1 BAZ1B ATM GSK3B EPHA5	1.62e-05	709	77	12	GO:0016773
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	CDK9 CDK16 MET CERK CMPK1 IGF2R RIPK1 PIK3R1 CSNK2A1 BAZ1B ATM GSK3B EPHA5	5.62e-05	938	77	13	GO:0016772
GeneOntologyMolecularFunction	protein kinase activity	CDK9 CDK16 MET IGF2R RIPK1 CSNK2A1 BAZ1B ATM GSK3B EPHA5	9.99e-05	600	77	10	GO:0004672
GeneOntologyMolecularFunction	histone H2AX kinase activity	BAZ1B ATM	1.46e-04	5	77	2	GO:0141003
GeneOntologyMolecularFunction	cytoskeletal protein binding	SNX6 RMDN1 CEP290 SPIRE1 TTLL1 MTCL1 NEB DYSF USH1C FMNL2 JAKMIP2 FKBP4 GSK3B	2.72e-04	1099	77	13	GO:0008092
GeneOntologyMolecularFunction	lipid kinase activity	CERK PIK3R1 ATM	5.29e-04	41	77	3	GO:0001727
GeneOntologyMolecularFunction	1-phosphatidylinositol-3-kinase activity	PIK3R1 ATM	7.89e-04	11	77	2	GO:0016303
GeneOntologyMolecularFunction	dynactin binding	SNX6 GSK3B	9.45e-04	12	77	2	GO:0034452
GeneOntologyMolecularFunction	phosphoprotein binding	IGF2R RB1 PIK3R1 FKBP4	1.09e-03	117	77	4	GO:0051219
GeneOntologyMolecularFunction	microtubule binding	RMDN1 CEP290 SPIRE1 MTCL1 DYSF JAKMIP2	1.21e-03	308	77	6	GO:0008017
GeneOntologyMolecularFunction	tubulin binding	RMDN1 CEP290 SPIRE1 TTLL1 MTCL1 DYSF JAKMIP2	1.31e-03	428	77	7	GO:0015631
GeneOntologyMolecularFunction	protein kinase A catalytic subunit binding	AKAP11 GSK3B	1.70e-03	16	77	2	GO:0034236
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	MET MNS1 RMDN1 CEP290 SPIRE1 TTLL1 ODAD4 MTCL1 SPAG17 DYSF DNAI3 FKBP4 GSK3B	2.79e-06	720	78	13	GO:0000226
GeneOntologyBiologicalProcess	cilium assembly	RPGRIP1 MNS1 GALNT11 CEP290 CEP41 TTLL1 ODAD4 SPAG17 DNAI3 GSK3B	6.58e-06	444	78	10	GO:0060271
GeneOntologyBiologicalProcess	cilium organization	RPGRIP1 MNS1 GALNT11 CEP290 CEP41 TTLL1 ODAD4 SPAG17 DNAI3 GSK3B	1.21e-05	476	78	10	GO:0044782
GeneOntologyBiologicalProcess	microtubule bundle formation	MNS1 TTLL1 ODAD4 MTCL1 SPAG17 DNAI3	1.84e-05	145	78	6	GO:0001578
GeneOntologyBiologicalProcess	negative regulation of organelle organization	MET SWAP70 GCLC PIK3R1 BAZ1B ATM DYSF DNAI3 FKBP4	2.97e-05	421	78	9	GO:0010639
GeneOntologyBiologicalProcess	regulation of organelle organization	MET MNS1 SWAP70 RB1 GCLC PIK3R1 BAZ1B SPIRE1 SMARCE1 ATM NEB DYSF DNAI3 FKBP4 GSK3B EPHA5	3.48e-05	1342	78	16	GO:0033043
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection assembly	RPGRIP1 MNS1 GALNT11 PIK3R1 CEP290 CEP41 TTLL1 ODAD4 SPAG17 DNAI3 GSK3B	4.21e-05	670	78	11	GO:0120031
GeneOntologyBiologicalProcess	cell projection assembly	RPGRIP1 MNS1 GALNT11 PIK3R1 CEP290 CEP41 TTLL1 ODAD4 SPAG17 DNAI3 GSK3B	5.14e-05	685	78	11	GO:0030031
GeneOntologyBiologicalProcess	supramolecular fiber organization	MET RIPK1 SWAP70 RB1 PIK3R1 KRT85 SPIRE1 NEB DYSF USH1C KRT87P DNAI3 FKBP4	5.70e-05	957	78	13	GO:0097435
GeneOntologyBiologicalProcess	axoneme assembly	MNS1 TTLL1 ODAD4 SPAG17 DNAI3	5.84e-05	109	78	5	GO:0035082
GeneOntologyBiologicalProcess	negative regulation of cytoskeleton organization	MET SWAP70 PIK3R1 DYSF DNAI3 FKBP4	9.38e-05	194	78	6	GO:0051494
GeneOntologyBiologicalProcess	negative regulation of supramolecular fiber organization	MET SWAP70 PIK3R1 DYSF DNAI3 FKBP4	1.02e-04	197	78	6	GO:1902904
GeneOntologyBiologicalProcess	negative regulation of protein modification process	MET SWAP70 SNX6 RB1 GCLC RTRAF CMYA5 DYSF GSK3B	1.33e-04	512	78	9	GO:0031400
GeneOntologyBiologicalProcess	regulation of autophagy	CDK16 MET SNX6 SUPT5H CSNK2A1 MTCL1 ATM GSK3B	1.34e-04	400	78	8	GO:0010506
GeneOntologyBiologicalProcess	microtubule-based process	MET MNS1 RMDN1 CEP290 SPIRE1 TTLL1 ODAD4 MTCL1 SPAG17 DYSF DNAI3 FKBP4 GSK3B	1.56e-04	1058	78	13	GO:0007017
GeneOntologyBiologicalProcess	peptidyl-amino acid modification	MET ARL2BP RIPK1 SNX6 GALNT11 ENPP2 CSNK2A1 CEP41 TTLL1 ATM FKBP4 GSK3B	2.86e-04	976	78	12	GO:0018193
GeneOntologyBiologicalProcess	parallel actin filament bundle assembly	SPIRE1 USH1C	2.93e-04	7	78	2	GO:0030046
GeneOntologyBiologicalProcess	organelle assembly	RPGRIP1 MNS1 GALNT11 RC3H1 CEP290 CEP41 TTLL1 ODAD4 ATM NEB SPAG17 DNAI3 GSK3B	3.18e-04	1138	78	13	GO:0070925
GeneOntologyBiologicalProcess	regulation of cytoskeleton organization	MET SWAP70 PIK3R1 NEB DYSF DNAI3 FKBP4 GSK3B EPHA5	3.31e-04	579	78	9	GO:0051493
GeneOntologyBiologicalProcess	chromosome segregation	RB1 RMDN1 CSNK2A1 BAZ1B SMARCE1 MTCL1 ATM TOP2B	3.70e-04	465	78	8	GO:0007059
GeneOntologyBiologicalProcess	regulation of protein modification process	MET ARL2BP FBN1 RIPK1 SWAP70 SNX6 RB1 GCLC PIK3R1 ENPP2 RTRAF AKAP11 CMYA5 DYSF GSK3B	4.02e-04	1488	78	15	GO:0031399
GeneOntologyBiologicalProcess	sister chromatid segregation	RB1 RMDN1 BAZ1B SMARCE1 ATM TOP2B	4.03e-04	254	78	6	GO:0000819
GeneOntologyBiologicalProcess	regulation of cellular response to stress	CDK9 MET PIK3R1 CSNK2A1 SPIRE1 SMARCE1 ATM TOP2B GSK3B	4.19e-04	598	78	9	GO:0080135
GeneOntologyBiologicalProcess	cilium movement	MET MNS1 TTLL1 ODAD4 SPAG17 DNAI3	4.65e-04	261	78	6	GO:0003341
GeneOntologyBiologicalProcess	chromatin remodeling	CDK9 RB1 SUPT5H SMARCA1 BAZ1B SMARCE1 CHD6 ATM NAA50 GSK3B	4.67e-04	741	78	10	GO:0006338
GeneOntologyBiologicalProcess	response to nitrosative stress	GCLC ATM	5.00e-04	9	78	2	GO:0051409
GeneOntologyBiologicalProcess	peptidyl-serine autophosphorylation	RIPK1 ATM	5.00e-04	9	78	2	GO:0036289
GeneOntologyCellularComponent	photoreceptor distal connecting cilium	RPGRIP1 CEP290	2.85e-04	7	78	2	GO:0120206
GeneOntologyCellularComponent	serine/threonine protein kinase complex	CDK9 CDK16 RB1 CSNK2A1 IFIT5	3.04e-04	157	78	5	GO:1902554
GeneOntologyCellularComponent	spindle	ARL2BP TTC28 RB1 RMDN1 RTRAF MTCL1 ATM GSK3B	3.69e-04	471	78	8	GO:0005819
GeneOntologyCellularComponent	supramolecular fiber	FBN1 MNS1 RMDN1 KRT85 TTLL1 MTCL1 CMYA5 NEB SPAG17 DYSF KRT87P FKBP4 GSK3B	3.93e-04	1179	78	13	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	FBN1 MNS1 RMDN1 KRT85 TTLL1 MTCL1 CMYA5 NEB SPAG17 DYSF KRT87P FKBP4 GSK3B	4.19e-04	1187	78	13	GO:0099081
GeneOntologyCellularComponent	protein kinase complex	CDK9 CDK16 RB1 CSNK2A1 IFIT5	4.38e-04	170	78	5	GO:1902911
GeneOntologyCellularComponent	SWI/SNF superfamily-type complex	RB1 SMARCA1 BAZ1B SMARCE1	4.59e-04	96	78	4	GO:0070603
GeneOntologyCellularComponent	cilium	RPGRIP1 MET ARL2BP MNS1 CEP290 CEP41 TTLL1 ODAD4 SPAG17 USH1C DNAI3	4.84e-04	898	78	11	GO:0005929
GeneOntologyCellularComponent	cyclin/CDK positive transcription elongation factor complex	CDK9 RB1	4.86e-04	9	78	2	GO:0008024
GeneOntologyCellularComponent	microtubule	MNS1 RMDN1 TTLL1 MTCL1 SPAG17 DYSF FKBP4 GSK3B	8.31e-04	533	78	8	GO:0005874
GeneOntologyCellularComponent	axoneme	RPGRIP1 MNS1 ODAD4 SPAG17 DNAI3	1.07e-03	207	78	5	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	RPGRIP1 MNS1 ODAD4 SPAG17 DNAI3	1.09e-03	208	78	5	GO:0097014
GeneOntologyCellularComponent	transcription elongation factor complex	CDK9 RB1 SUPT5H	1.20e-03	56	78	3	GO:0008023
GeneOntologyCellularComponent	ISWI-type complex	SMARCA1 BAZ1B	1.21e-03	14	78	2	GO:0031010
GeneOntologyCellularComponent	PML body	CDK9 RB1 CSNK2A1 ZMYM2	1.24e-03	125	78	4	GO:0016605
GeneOntologyCellularComponent	ATPase complex	RB1 SMARCA1 BAZ1B SMARCE1	1.39e-03	129	78	4	GO:1904949
GeneOntologyCellularComponent	cyclin-dependent protein kinase holoenzyme complex	CDK9 CDK16 RB1	1.54e-03	61	78	3	GO:0000307
GeneOntologyCellularComponent	transferase complex, transferring phosphorus-containing groups	CDK9 CDK16 RB1 PIK3R1 CSNK2A1 IFIT5	1.58e-03	335	78	6	GO:0061695
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	MNS1 RMDN1 KRT85 TTLL1 MTCL1 SPAG17 DYSF KRT87P FKBP4 GSK3B	1.83e-03	899	78	10	GO:0099513
GeneOntologyCellularComponent	nuclear cyclin-dependent protein kinase holoenzyme complex	CDK9 RB1	2.02e-03	18	78	2	GO:0019908
GeneOntologyCellularComponent	microtubule organizing center	ARL2BP TTC28 RTRAF CEP290 CEP41 AKAP11 TTLL1 ATM DYSF GSK3B	2.15e-03	919	78	10	GO:0005815
GeneOntologyCellularComponent	centrosome	ARL2BP TTC28 RTRAF CEP290 CEP41 AKAP11 ATM DYSF GSK3B	2.24e-03	770	78	9	GO:0005813
HumanPheno	High hypermetropia	RPGRIP1 PIK3R1 ZMYM2 BAZ1B HARS1 USH1C	5.11e-06	82	29	6	HP:0008499
HumanPheno	Abdominal situs inversus	RPGRIP1 ARL2BP MNS1 CEP290 CEP41 ODAD4 CHD6	1.05e-05	142	29	7	HP:0003363
HumanPheno	Situs inversus totalis	RPGRIP1 ARL2BP MNS1 CEP290 CEP41 ODAD4 CHD6	1.05e-05	142	29	7	HP:0001696
HumanPheno	Abnormal spatial orientation of the cardiac segments	RPGRIP1 ARL2BP MNS1 CEP290 CEP41 ODAD4 CHD6	1.05e-05	142	29	7	HP:0011534
HumanPheno	Abnormality of abdominal situs	RPGRIP1 ARL2BP MNS1 CEP290 CEP41 ODAD4 CHD6	1.05e-05	142	29	7	HP:0011620
HumanPheno	Heterotaxy	RPGRIP1 ARL2BP MNS1 CEP290 CEP41 ODAD4 CHD6	1.21e-05	145	29	7	HP:0030853
HumanPheno	Dextrocardia	RPGRIP1 ARL2BP MNS1 CEP290 CEP41 ODAD4 CHD6	2.21e-05	159	29	7	HP:0001651
HumanPheno	Abnormal anatomic location of the heart	RPGRIP1 ARL2BP MNS1 CEP290 CEP41 ODAD4 CHD6	2.31e-05	160	29	7	HP:0004307
Domain	TPR_REGION	TTC28 RMDN1 IFIT5 ODAD4 FKBP4	5.64e-04	165	76	5	PS50293
Domain	TPR	TTC28 RMDN1 IFIT5 ODAD4 FKBP4	5.64e-04	165	76	5	PS50005
Domain	TPR_2	TTC28 IFIT5 FKBP4	1.11e-03	50	76	3	PF07719
Domain	TPR_2	TTC28 IFIT5 FKBP4	1.11e-03	50	76	3	IPR013105
Domain	TPR_8	TTC28 IFIT5 ODAD4	1.31e-03	53	76	3	PF13181
Domain	-	TTC28 RMDN1 IFIT5 ODAD4 FKBP4	1.56e-03	207	76	5	1.25.40.10
Domain	Kinase-like_dom	CDK9 CDK16 MET RIPK1 CSNK2A1 ATM GSK3B EPHA5	1.59e-03	542	76	8	IPR011009
Domain	TPR	TTC28 IFIT5 ODAD4 FKBP4	1.90e-03	129	76	4	SM00028
Domain	TPR_repeat	TTC28 IFIT5 ODAD4 FKBP4	2.12e-03	133	76	4	IPR019734
Domain	TPR-like_helical_dom	TTC28 RMDN1 IFIT5 ODAD4 FKBP4	2.61e-03	233	76	5	IPR011990
Domain	TPR-contain_dom	TTC28 IFIT5 ODAD4 FKBP4	3.28e-03	150	76	4	IPR013026
Domain	Prot_kinase_dom	CDK9 CDK16 MET RIPK1 CSNK2A1 GSK3B EPHA5	3.73e-03	489	76	7	IPR000719
Domain	PROTEIN_KINASE_DOM	CDK9 CDK16 MET RIPK1 CSNK2A1 GSK3B EPHA5	3.89e-03	493	76	7	PS50011
Domain	Protein_kinase_ATP_BS	CDK9 CDK16 MET CSNK2A1 GSK3B EPHA5	4.45e-03	379	76	6	IPR017441
Domain	TPR_1	TTC28 IFIT5 FKBP4	5.90e-03	90	76	3	PF00515
Domain	TPR_1	TTC28 IFIT5 FKBP4	5.90e-03	90	76	3	IPR001440
Domain	TIG	MET EXOC2	7.04e-03	31	76	2	PF01833
Domain	ATP_grasp_subdomain_2	TTLL1 SUCLG2	7.04e-03	31	76	2	IPR013816
Domain	SNF2_N	SMARCA1 CHD6	7.49e-03	32	76	2	IPR000330
Domain	IPT	MET EXOC2	7.49e-03	32	76	2	IPR002909
Domain	SNF2_N	SMARCA1 CHD6	7.49e-03	32	76	2	PF00176
Pathway	WP_ANDROGEN_RECEPTOR_SIGNALING	RB1 PIK3R1 SMARCE1 FKBP4 GSK3B	3.22e-05	91	57	5	M39700
Pathway	BIOCARTA_VDR_PATHWAY	BAZ1B SMARCE1 TOP2B	9.14e-05	22	57	3	MM1370
Pathway	WP_CILIOPATHIES	RPGRIP1 ARL2BP GALNT11 CEP290 CEP41 ODAD4	9.52e-05	184	57	6	M39880
Pathway	BIOCARTA_VDR_PATHWAY	BAZ1B SMARCE1 TOP2B	1.19e-04	24	57	3	M13404
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FBN1 TTC28 SNX6 SUPT5H PIK3R1 ENPP2 RTRAF CEP290 ZMYM2 IFIT5 SMARCE1 CHD6 ATM HARS1 CMYA5 SEC31B FMNL2	2.99e-09	1285	78	17	35914814
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	GBA3 IGF2R CACNA2D2 GCLC SUPT5H CSNK2A1 RTRAF SMARCA1 NUP133 BAZ1B SMARCE1 ATM HARS1 CMYA5 FKBP4 TOP2B	9.06e-08	1425	78	16	30948266
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	ZCWPW2 TTC28 SUPT5H CEP290 SMARCA1 NUP133 CHD6 UNC79 CDCA7L TOP2B	1.00e-07	469	78	10	27634302
Pubmed	Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.	CDK9 MET RB1 PIK3R1 ATM	5.78e-07	71	78	5	28319113
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	MET CCDC82 PIK3R1 CSNK2A1 KRT85 NUP133 SPIRE1 AKAP11 ODAD4 CMYA5 APRT UNC79 FKBP4 GSK3B	9.17e-07	1284	78	14	17353931
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	RPGRIP1 ARL2BP RB1 PIK3R1 CEP290 USH1C TOP2B	9.76e-07	233	78	7	32290105
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	CDK16 RPGRIP1 ARL2BP MNS1 RB1 SUPT5H PIK3R1 CSNK2A1 CEP290 NUP133 SPIRE1 EXOC2 USH1C FMNL2	1.28e-06	1321	78	14	27173435
Pubmed	Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor.	ARHGAP22 CSNK2A1 RC3H1 APRT GSK3B	2.10e-06	92	78	5	20368287
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	CDK9 CMPK1 RB1 SUPT5H CSNK2A1 NUP133 BAZ1B SMARCE1 ATM CDCA7L FKBP4 TOP2B	2.62e-06	1014	78	12	32416067
Pubmed	Receptor tyrosine kinase EphA5 is a functional molecular target in human lung cancer.	ATM EPHA5	4.97e-06	2	78	2	25623065
Pubmed	Phosphorylation of the immunosuppressant FK506-binding protein FKBP52 by casein kinase II: regulation of HSP90-binding activity of FKBP52.	CSNK2A1 FKBP4	4.97e-06	2	78	2	9405642
Pubmed	ATM Regulated PTEN Degradation Is XIAP E3 Ubiquitin Ligase Mediated in p85α Deficient Cancer Cells and Influence Platinum Sensitivity.	PIK3R1 CSNK2A1	4.97e-06	2	78	2	31635307
Pubmed	Glycogen synthase kinase-3beta regulates post-myocardial infarction remodeling and stress-induced cardiomyocyte proliferation in vivo.	A1CF GSK3B	4.97e-06	2	78	2	20360256
Pubmed	Linking ATM Promoter Methylation to Cell Cycle Protein Expression in Brain Tumor Patients: Cellular Molecular Triangle Correlation in ATM Territory.	RB1 ATM	4.97e-06	2	78	2	25159481
Pubmed	Solid tissues removed from ATM homozygous deficient mice do not exhibit a mutator phenotype for second-step autosomal mutations.	ATM APRT	4.97e-06	2	78	2	10519383
Pubmed	Ionizing radiation can induce GSK-3beta phosphorylation and NF-kappaB transcriptional transactivation in ATM-deficient fibroblasts.	ATM GSK3B	4.97e-06	2	78	2	18243662
Pubmed	Both variants of A1CF and BAZ1B genes are associated with gout susceptibility: a replication study and meta-analysis in a Japanese population.	A1CF BAZ1B	4.97e-06	2	78	2	33517564
Pubmed	Identification of the molecular basis of doxorubicin-induced cardiotoxicity.	A1CF TOP2B	4.97e-06	2	78	2	23104132
Pubmed	ATM-activated autotaxin (ATX) propagates inflammation and DNA damage in lung epithelial cells: a new mode of action for silica-induced DNA damage?	ENPP2 ATM	4.97e-06	2	78	2	28968864
Pubmed	Proteomic analysis of DZIP3 interactome and its role in proliferation and metastasis in gastric cancer cells.	RB1 CSNK2A1 SMARCA1 SMARCE1	6.30e-06	53	78	4	36841324
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	CMPK1 RC3H1 RTRAF NUP133 BAZ1B SMARCE1 FKBP4 GSK3B	8.77e-06	457	78	8	32344865
Pubmed	A protein interaction landscape of breast cancer.	CDK16 IGF2R TTC28 RB1 SUPT5H PIK3R1 SMARCE1 FKBP4 TOP2B	1.25e-05	634	78	9	34591612
Pubmed	Genetic mutations associated with cigarette smoking in pancreatic cancer.	MET RB1 PIK3R1 ATM	1.26e-05	63	78	4	19351817
Pubmed	A human MAP kinase interactome.	ARL2BP RIPK1 PIK3R1 CEP290 ZMYM2 CHD6 NEB FMNL2	1.37e-05	486	78	8	20936779
Pubmed	CECR2 is involved in spermatogenesis and forms a complex with SNF2H in the testis.	MET SMARCA1 BAZ1B	1.40e-05	21	78	3	22154806
Pubmed	Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element.	CDK9 SUPT5H	1.49e-05	3	78	2	14701750
Pubmed	Wnt signaling in hepatocellular carcinoma: analysis of mutation and expression of beta-catenin, T-cell factor-4 and glycogen synthase kinase 3-beta genes.	FKBP4 GSK3B	1.49e-05	3	78	2	12603528
Pubmed	Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcription.	CDK9 SUPT5H	1.49e-05	3	78	2	15564463
Pubmed	A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family.	MET PIK3R1	1.49e-05	3	78	2	7513258
Pubmed	Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy.	A1CF GSK3B	1.49e-05	3	78	2	26976650
Pubmed	Hepatocyte growth factor, a determinant of airspace homeostasis in the murine lung.	MET FBN1	1.49e-05	3	78	2	23459311
Pubmed	Dysferlin deficiency enhances monocyte phagocytosis: a model for the inflammatory onset of limb-girdle muscular dystrophy 2B.	IGF2R DYSF	1.49e-05	3	78	2	18276788
Pubmed	High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients.	MET PIK3R1	1.49e-05	3	78	2	25746038
Pubmed	Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro.	CDK9 SUPT5H	1.49e-05	3	78	2	9857195
Pubmed	The N-terminal 24 amino acids of the p55 gamma regulatory subunit of phosphoinositide 3-kinase binds Rb and induces cell cycle arrest.	RB1 PIK3R1	1.49e-05	3	78	2	12588990
Pubmed	ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53.	MET ATM	1.49e-05	3	78	2	22660439
Pubmed	Protein Kinase A Opposes the Phosphorylation-dependent Recruitment of Glycogen Synthase Kinase 3β to A-kinase Anchoring Protein 220.	AKAP11 GSK3B	1.49e-05	3	78	2	26088133
Pubmed	The CDC2-related kinase PITALRE is the catalytic subunit of active multimeric protein complexes.	CDK9 RB1	1.49e-05	3	78	2	8870681
Pubmed	[CK2α Regulates the Metastases and Migration of Lung Adenocarcinoma  A549 Cell Line through PI3K/Akt/GSK-3β Signal Pathway].	CSNK2A1 GSK3B	1.49e-05	3	78	2	28442011
Pubmed	Casein Kinase II (CK2), Glycogen Synthase Kinase-3 (GSK-3) and Ikaros mediated regulation of leukemia.	CSNK2A1 GSK3B	1.49e-05	3	78	2	28623166
Pubmed	A novel ninein-interaction protein, CGI-99, blocks ninein phosphorylation by GSK3beta and is highly expressed in brain tumors.	RTRAF GSK3B	1.49e-05	3	78	2	15147888
Pubmed	Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta.	CSNK2A1 GSK3B	1.49e-05	3	78	2	16107342
Pubmed	Binding of CDK9 to TRAF2.	CDK9 RB1	1.49e-05	3	78	2	9827693
Pubmed	pRb-dependent cyclin D3 protein stabilization is required for myogenic differentiation.	RB1 GSK3B	1.49e-05	3	78	2	17709384
Pubmed	Clinical and molecular findings in a cohort of 152 Brazilian severe early onset inherited retinal dystrophy patients.	RPGRIP1 CEP290	1.49e-05	3	78	2	32865313
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	IGF2R SNX6 SUPT5H PIK3R1 CSNK2A1 CEP290 NUP133 NAA50 HARS1 FKBP4 GSK3B	2.19e-05	1049	78	11	27880917
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	SUPT5H CSNK2A1 SMARCA1 ZMYM2 SMARCE1	2.29e-05	150	78	5	28242625
Pubmed	Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.	CDK9 CDK16 MET GSK3B	2.94e-05	78	78	4	17192257
Pubmed	The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.	RB1 ATM	2.97e-05	4	78	2	17562874
Pubmed	Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1.	CDK16 RB1	2.97e-05	4	78	2	19524571
Pubmed	Phosphorylation and SCF-mediated degradation regulate CREB-H transcription of metabolic targets.	CSNK2A1 GSK3B	2.97e-05	4	78	2	26108621
Pubmed	Arsenic impairs insulin signaling in differentiated neuroblastoma SH-SY5Y cells.	PIK3R1 GSK3B	2.97e-05	4	78	2	29526746
Pubmed	Casein kinase II phosphorylation of E-cadherin increases E-cadherin/beta-catenin interaction and strengthens cell-cell adhesion.	CSNK2A1 GSK3B	2.97e-05	4	78	2	10671552
Pubmed	Ganglioside GM3 promotes HGF-stimulated motility of murine hepatoma cell through enhanced phosphorylation of cMet at specific tyrosine sites and PI3K/Akt-mediated migration signaling.	MET PIK3R1	2.97e-05	4	78	2	23749170
Pubmed	Quantification of Oxygen Consumption in Retina Ex Vivo Demonstrates Limited Reserve Capacity of Photoreceptor Mitochondria.	RPGRIP1 CEP290	2.97e-05	4	78	2	26747773
Pubmed	Targeted disruption of glycogen synthase kinase-3β in cardiomyocytes attenuates cardiac parasympathetic dysfunction in type 1 diabetic Akita mice.	A1CF GSK3B	2.97e-05	4	78	2	30978208
Pubmed	Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer.	RB1 ATM	2.97e-05	4	78	2	26928463
Pubmed	The peptidyl-prolyl isomerase Pin1 interacts with hSpt5 phosphorylated by Cdk9.	CDK9 SUPT5H	2.97e-05	4	78	2	11575923
Pubmed	ATM regulates ionizing radiation-induced disruption of HDAC1:PP1:Rb complexes.	RB1 ATM	2.97e-05	4	78	2	17008050
Pubmed	Autoinhibition of the ligand-binding site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif.	IGF2R CSNK2A1	2.97e-05	4	78	2	12060753
Pubmed	Cdk9 phosphorylates p53 on serine 392 independently of CKII.	CDK9 CSNK2A1	2.97e-05	4	78	2	16741955
Pubmed	Akt-independent GSK3 inactivation downstream of PI3K signaling regulates mammalian axon regeneration.	PIK3R1 GSK3B	2.97e-05	4	78	2	24333443
Pubmed	Silencing glycogen synthase kinase-3beta inhibits acetaminophen hepatotoxicity and attenuates JNK activation and loss of glutamate cysteine ligase and myeloid cell leukemia sequence 1.	GCLC GSK3B	2.97e-05	4	78	2	20061376
Pubmed	Physical interaction between pRb and cdk9/cyclinT2 complex.	CDK9 RB1	2.97e-05	4	78	2	12037672
Pubmed	Insulin-stimulated kinase from rat fat cells that phosphorylates initiation factor 4E-binding protein 1 on the rapamycin-insensitive site (serine-111).	CSNK2A1 ATM	2.97e-05	4	78	2	9806882
Pubmed	PITALRE, a nuclear CDC2-related protein kinase that phosphorylates the retinoblastoma protein in vitro.	CDK9 RB1	2.97e-05	4	78	2	8170997
Pubmed	ATM regulates NF-κB-dependent immediate-early genes via RelA Ser 276 phosphorylation coupled to CDK9 promoter recruitment.	CDK9 ATM	2.97e-05	4	78	2	24957606
Pubmed	Activation of casein kinase II and inhibition of phosphatase and tensin homologue deleted on chromosome 10 phosphatase by nerve growth factor/p75NTR inhibit glycogen synthase kinase-3beta and stimulate axonal growth.	CSNK2A1 GSK3B	2.97e-05	4	78	2	16723502
Pubmed	CK2 forms a stable complex with TFIIIB and activates RNA polymerase III transcription in human cells.	RB1 CSNK2A1	2.97e-05	4	78	2	11997511
Pubmed	Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1.	CSNK2A1 ATM	2.97e-05	4	78	2	11146653
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	MET CMPK1 IGF2R SWAP70 SNX6 CSNK2A1 RTRAF MTCL1 HARS1 APRT FKBP4 GSK3B	3.07e-05	1297	78	12	33545068
Pubmed	Hepatocyte growth factor (Hgf) stimulates low density lipoprotein receptor-related protein (Lrp) 5/6 phosphorylation and promotes canonical Wnt signaling.	MET GSK3B	4.94e-05	5	78	2	24692544
Pubmed	Synergistic inhibition of cell migration by tetraspanin CD82 and gangliosides occurs via the EGFR or cMet-activated Pl3K/Akt signalling pathway.	MET PIK3R1	4.94e-05	5	78	2	23968914
Pubmed	A Japanese-specific allele in the GALNT11 gene.	FBN1 GALNT11	4.94e-05	5	78	2	20547088
Pubmed	Lack of Rb and p53 delays cerebellar development and predisposes to large cell anaplastic medulloblastoma through amplification of N-Myc and Ptch2.	RB1 ATM	4.94e-05	5	78	2	16707443
Pubmed	The chromatin remodeler CHD6 promotes colorectal cancer development by regulating TMEM65-mediated mitochondrial dynamics via EGF and Wnt signaling.	CHD6 GSK3B	4.94e-05	5	78	2	36473865
Pubmed	Differential regulation of NF-kappaB by elongation factors is determined by core promoter type.	CDK9 SUPT5H	4.94e-05	5	78	2	17502349
Pubmed	Functional expression of O-linked GlcNAc transferase. Domain structure and substrate specificity.	CSNK2A1 GSK3B	4.94e-05	5	78	2	10753899
Pubmed	PIDD death-domain phosphorylation by ATM controls prodeath versus prosurvival PIDDosome signaling.	RIPK1 ATM	4.94e-05	5	78	2	22854598
Pubmed	ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage.	CSNK2A1 ATM	4.94e-05	5	78	2	22361354
Pubmed	CDC2-related kinase PITALRE phosphorylates pRb exclusively on serine and is widely expressed in human tissues.	CDK9 RB1	4.94e-05	5	78	2	9258347
Pubmed	Cdc42 and phosphoinositide 3-kinase drive Rac-mediated actin polymerization downstream of c-Met in distinct and common pathways.	MET PIK3R1	4.94e-05	5	78	2	17682062
Pubmed	The A-Kinase Anchoring Protein (AKAP) Glycogen Synthase Kinase 3β Interaction Protein (GSKIP) Regulates β-Catenin through Its Interactions with Both Protein Kinase A (PKA) and GSK3β.	AKAP11 GSK3B	4.94e-05	5	78	2	27484798
Pubmed	Methylation of SPT5 regulates its interaction with RNA polymerase II and transcriptional elongation properties.	CDK9 SUPT5H	4.94e-05	5	78	2	12718890
Pubmed	Novel mechanism by which histone deacetylase inhibitors facilitate topoisomerase IIα degradation in hepatocellular carcinoma cells.	CSNK2A1 GSK3B	4.94e-05	5	78	2	21254166
Pubmed	Inactivation of nuclear GSK3β by Ser(389) phosphorylation promotes lymphocyte fitness during DNA double-strand break response.	ATM GSK3B	4.94e-05	5	78	2	26822034
Pubmed	Knockdown of Fbxo7 reveals its regulatory role in proliferation and differentiation of haematopoietic precursor cells.	RB1 CSNK2A1	4.94e-05	5	78	2	21652635
Pubmed	Consensus nomenclature for dyneins and associated assembly factors.	ODAD4 DNAI3	4.94e-05	5	78	2	35006274
Pubmed	Chromatin loop organization of the junb locus in mouse dendritic cells.	CDK9 SUPT5H	4.94e-05	5	78	2	23921639
Pubmed	Autotaxin stimulates urokinase-type plasminogen activator expression through phosphoinositide 3-kinase-Akt-nuclear [corrected] factor kappa B signaling cascade in human melanoma cells.	PIK3R1 ENPP2	4.94e-05	5	78	2	17013094
Pubmed	A PACS-1, GGA3 and CK2 complex regulates CI-MPR trafficking.	IGF2R CSNK2A1	4.94e-05	5	78	2	16977309
Pubmed	Positive transcription elongation factor B phosphorylates hSPT5 and RNA polymerase II carboxyl-terminal domain independently of cyclin-dependent kinase-activating kinase.	CDK9 SUPT5H	4.94e-05	5	78	2	11145967
Pubmed	Protein kinase CKII regulates the interaction of beta-catenin with alpha-catenin and its protein stability.	CSNK2A1 GSK3B	4.94e-05	5	78	2	12432063
Pubmed	Phosphorylation of Grb14 BPS domain by GSK-3 correlates with complex forming of Grb14 and insulin receptor.	CSNK2A1 GSK3B	4.94e-05	5	78	2	24535599
Pubmed	FACT relieves DSIF/NELF-mediated inhibition of transcriptional elongation and reveals functional differences between P-TEFb and TFIIH.	CDK9 SUPT5H	4.94e-05	5	78	2	10912001
Pubmed	GSK-3beta acts downstream of PP2A and the PI 3-kinase-Akt pathway, and upstream of caspase-2 in ceramide-induced mitochondrial apoptosis.	PIK3R1 GSK3B	4.94e-05	5	78	2	17666435
Pubmed	Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells.	RB1 SUPT5H ZMYM2 SMARCE1 GSK3B	5.18e-05	178	78	5	27637333
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	RB1 CSNK2A1 SMARCA1 ZMYM2 BAZ1B SMARCE1 CHD6 TOP2B	6.67e-05	608	78	8	36089195
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	CDK9 SUPT5H CSNK2A1 RC3H1 RTRAF SMARCA1 SMARCE1 TOP2B	7.22e-05	615	78	8	31048545
Pubmed	SCFβ-TrCP-mediated degradation of TOP2β promotes cancer cell survival in response to chemotherapeutic drugs targeting topoisomerase II.	ATM TOP2B	7.40e-05	6	78	2	32015321
Interaction	SNX32 interactions	IGF2R MNS1 SNX6 PIK3R1	2.47e-06	25	78	4	int:SNX32
Interaction	H2AZ1 interactions	RIPK1 SUPT5H RC3H1 SMARCA1 ZMYM2 BAZ1B SMARCE1 AKAP11 TOP2B	1.31e-05	371	78	9	int:H2AZ1
Interaction	H2BC21 interactions	CDK9 SUPT5H SMARCA1 NUP133 ZMYM2 BAZ1B SMARCE1 AKAP11 NEB FMNL2 CDCA7L TOP2B	1.41e-05	696	78	12	int:H2BC21
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	TTC28 IFIT5 ODAD4 FKBP4	1.73e-04	115	44	4	769
GeneFamily	Cyclin dependent kinases	CDK9 CDK16	1.81e-03	26	44	2	496
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	AKAP11 CMYA5	2.25e-03	29	44	2	396
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	IGF2R TTC28 SWAP70 RB1 CSNK2A1 SMARCA1 NUP133 ZMYM2 BAZ1B AKAP11 MTCL1 GSK3B SEC14L1	1.36e-06	856	78	13	M4500
Coexpression	GSE17186_MEMORY_VS_CD21HIGH_TRANSITIONAL_BCELL_UP	RPGRIP1 ARHGAP22 NUP133 CHD6 CMYA5 NEB DYSF	2.12e-06	198	78	7	M7200
Coexpression	GSE3982_DC_VS_MAC_LPS_STIM_UP	CEP41 NUP133 BAZ1B PCDHA2 MTCL1 HARS1 SEC14L1	2.27e-06	200	78	7	M5387
Coexpression	GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_UP	ZCWPW2 SWAP70 GALNT11 ZMYM2 SPIRE1 SMARCE1	2.74e-05	197	78	6	M3133
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FBN1 TTC28 SWAP70 RAPGEF5 ENPP2 SEC14L1	7.39e-07	179	78	6	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DUOXA1 MNS1 CACNA2D2 ODAD4 SPAG17 DNAI3	1.15e-06	193	78	6	bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	IGF2R TTC28 MTG2 BAZ1B SPIRE1	1.94e-05	187	78	5	689b3cc76f1e04bd35a7d3ce19e9f08744a7835b
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IGF2R TTC28 MTG2 BAZ1B SPIRE1	1.94e-05	187	78	5	4527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	MET SWAP70 RAPGEF5 ENPP2 SEC14L1	1.94e-05	187	78	5	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MNS1 CEP290 ODAD4 SPAG17 DNAI3	2.15e-05	191	78	5	bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MNS1 CEP290 ODAD4 SPAG17 DNAI3	2.15e-05	191	78	5	6880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MNS1 GCLC CEP290 SPIRE1 HARS1	2.15e-05	191	78	5	24ebc8d4a9fc3782510162e04fe586f7cb371eed
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MNS1 CEP290 ODAD4 SPAG17 DNAI3	2.20e-05	192	78	5	b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCell	PND03-Epithelial-Epithelial_Airway\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MNS1 CEP290 ODAD4 SPAG17 DNAI3	2.20e-05	192	78	5	2d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MET DUOXA1 CACNA2D2 RAPGEF5 SPIRE1	2.26e-05	193	78	5	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MET DUOXA1 CACNA2D2 RAPGEF5 SPIRE1	2.26e-05	193	78	5	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MET DUOXA1 CACNA2D2 RAPGEF5 SPIRE1	2.32e-05	194	78	5	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TTC28 RAPGEF5 ENPP2 DYSF SEC14L1	2.43e-05	196	78	5	b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TTC28 RAPGEF5 ENPP2 DYSF SEC14L1	2.43e-05	196	78	5	145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TTC28 RAPGEF5 ENPP2 DYSF SEC14L1	2.43e-05	196	78	5	d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MET SWAP70 RAPGEF5 ENPP2 SEC14L1	2.49e-05	197	78	5	61b1b10a017cbeb17f8529fcae66cba77ee2f115
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MNS1 CEP290 ODAD4 SPAG17 DNAI3	2.49e-05	197	78	5	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SWAP70 RAPGEF5 ENPP2 DYSF SEC14L1	2.49e-05	197	78	5	c29ed0e706999d4c2b93e6e3bf46c42aeceb4813
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MET DUOXA1 CACNA2D2 RAPGEF5 SPIRE1	2.55e-05	198	78	5	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MET DUOXA1 CACNA2D2 RAPGEF5 SPIRE1	2.55e-05	198	78	5	2e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	MNS1 GALNT11 CEP290 SMARCE1 SPAG17	2.61e-05	199	78	5	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	COVID-19_Convalescent-PLT_3\|World / Disease Group and Platelet Clusters	CHD6 ATM HARS1 FKBP4	9.85e-05	137	78	4	bb54bb81b450462ad521b57e1a07a80ce1678e67
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CCDC83 FBN1 PIK3R1 TTLL1	1.23e-04	145	78	4	42dd36c1bc2c43cfea7196e89f901e4ea2a403c7
ToppCell	368C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DUOXA1 RIPK1 CEP290 NUP133	1.36e-04	149	78	4	f53151d9e5e724a61be0ee6a8c740d1990f28d5f
ToppCell	368C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DUOXA1 RIPK1 CEP290 NUP133	1.36e-04	149	78	4	9286bc56ff2e245630537a0bda5f1a1e17be863a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CERK RMDN1 FAM186A FMNL2	1.51e-04	153	78	4	ee6f4770c6e35d59bdeec5b0ecb10119fa8c3ca5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CERK RMDN1 FAM186A FMNL2	1.51e-04	153	78	4	a35149a0c8b4ec9ad27cc4b3d34fba3b8714a6a2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CERK RMDN1 FAM186A FMNL2	1.51e-04	153	78	4	90cd6efda83c0b4b80eae2c90e7ff45dfd936dc2
ToppCell	5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RPGRIP1 SWAP70 RAPGEF5 ATM	1.62e-04	156	78	4	203ef22eb76bd2b829b027c30af0557080f4006c
ToppCell	368C-Fibroblasts-Fibroblast-F\|368C / Donor, Lineage, Cell class and subclass (all cells)	FBN1 RIPK1 CEP290 NUP133	1.67e-04	157	78	4	74038192f016f95f80e0189035ee8ccc22ceb1b8
ToppCell	368C-Fibroblasts-Fibroblast-F-\|368C / Donor, Lineage, Cell class and subclass (all cells)	FBN1 RIPK1 CEP290 NUP133	1.67e-04	157	78	4	982e6ea78c7dabdb7c07c4a5fb2425d5e45b5b94
ToppCell	lung-Ciliated_Epithelia\|lung / shred on tissue and cell subclass	MNS1 ODAD4 SPAG17 DNAI3	2.11e-04	167	78	4	26cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	TTC28 DNAJC25 NEB FMNL2	2.11e-04	167	78	4	b5d15773be32cd277125fd3b4056a8fefaefa5ec
ToppCell	Int-URO-Lymphocyte-B-B_intermediate\|Int-URO / Disease, Lineage and Cell Type	SWAP70 FAM186A MTCL1 NEB	2.16e-04	168	78	4	5b3fb1fc8fea810c6d4e6feb42c24fb57e8066de
ToppCell	Ciliated_cells-A-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	MNS1 ODAD4 SPAG17 DNAI3	2.26e-04	170	78	4	3d3a03979014df3a05c49be18010c6b94d786707
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SWAP70 RAPGEF5 MTCL1 CDCA7L	2.31e-04	171	78	4	c3e3ea09c73050372314a89b282e36ba5f339d73
ToppCell	droplet-Liver-nan-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP290 MTCL1 DYSF FMNL2	2.36e-04	172	78	4	1f335ccb92b22d0412954e8fc3af212f96410b67
ToppCell	3'_v3-blood-Lymphocytic_B-Naive_B_cells\|blood / Manually curated celltypes from each tissue	MNS1 SWAP70 RAPGEF5 MTCL1	2.36e-04	172	78	4	f16f90d17feac1ee52fd513907b28456865fd31d
ToppCell	droplet-Liver-nan-3m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP290 MTCL1 DYSF FMNL2	2.36e-04	172	78	4	bb96c896d125e10b71e94e2bdad243899045af5c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 DYSF FMNL2 SEC14L1	2.36e-04	172	78	4	c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIK3R1 CEP41 ATM DNAI3	2.41e-04	173	78	4	79d11f94a8f6a420c18c2fef0da77e9af3204765
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MNS1 ODAD4 SPAG17 DNAI3	2.63e-04	177	78	4	3cfde67b93f3986312f5e74e42504214d966e7dc
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MNS1 ODAD4 SPAG17 DNAI3	2.63e-04	177	78	4	12a52a12a87a31e501ced611f46a90d172ca7e35
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MET SWAP70 RAPGEF5 SEC14L1	2.75e-04	179	78	4	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	facs-Trachea-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MNS1 ODAD4 SPAG17 DNAI3	2.81e-04	180	78	4	cf6e9f757afeb342c5023f6e6152a1b4d0d164b4
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RB1 RAPGEF5 DYSF SEC14L1	2.81e-04	180	78	4	97e0dcb7cfbba60a782824c5e23995058609fcd4
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	TTC28 MTG2 BAZ1B SPIRE1	2.87e-04	181	78	4	b193f3606554adc55c5906219d114288bb1f978a
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SMARCA1 PCDHA2 CDCA7L EPHA5	3.05e-04	184	78	4	a6dee97ee4ef9d89e11d17339e0dadaea1210ce5
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEB SPAG17 UNC79 EPHA5	3.05e-04	184	78	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Lung-EPCAM-24m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MNS1 ODAD4 SPAG17 DNAI3	3.05e-04	184	78	4	afb11ab301ef9801333dbb53ccff4bd0d44f1677
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SWAP70 RAPGEF5 MTCL1 CDCA7L	3.05e-04	184	78	4	d18e94839a62fca536ae1630c154e5d0aafc44c5
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	MET DUOXA1 CACNA2D2 RAPGEF5	3.05e-04	184	78	4	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	facs-Lung-EPCAM-24m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MNS1 ODAD4 SPAG17 DNAI3	3.05e-04	184	78	4	a411c0bcb283534a1c15f22473c46b7d87e01294
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEB SPAG17 UNC79 EPHA5	3.05e-04	184	78	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEB SPAG17 UNC79 EPHA5	3.05e-04	184	78	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	TTC28 RAPGEF5 ENPP2 SEC14L1	3.05e-04	184	78	4	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4\|TCGA-Thryoid / Sample_Type by Project: Shred V9	CDK16 MET IGF2R SPIRE1	3.05e-04	184	78	4	d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCell	Control-Lymphoid-ILC_A\|Lymphoid / Disease state, Lineage and Cell class	GALNT11 PIK3R1 MTCL1 SEC14L1	3.11e-04	185	78	4	520795866d44def5be3910ce8e728045c716a24d
ToppCell	Ciliated_cells-A-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	MNS1 ODAD4 SPAG17 DNAI3	3.11e-04	185	78	4	d77ca57b02125a3a57a37f4aed20c89803b7d551
ToppCell	normal-na-Lymphocytic_T-CytoT_GZMH+-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	CACNA2D2 PIK3R1 FAM186A JAKMIP2	3.11e-04	185	78	4	097d628f92e13250c15b550f2fd1f4225fc07558
ToppCell	COVID-19_Convalescent-PLT_4\|World / Disease Group and Platelet Clusters	CDK9 GALNT11 NUP133 ZMYM2	3.18e-04	186	78	4	5954a1e3ffafb33f2a9bc87af3343f304fda4c92
ToppCell	Substantia_nigra-Neuronal-Inhibitory\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CACNA2D2 UNC79 GSK3B EPHA5	3.18e-04	186	78	4	9d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MNS1 ODAD4 SPAG17 DNAI3	3.18e-04	186	78	4	903af26a63ec4b1755ab5cb81dfeb8dbd14bc5db
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MNS1 ODAD4 SPAG17 DNAI3	3.24e-04	187	78	4	04dba2ed09ee4180830bdf0191921696697ea234
ToppCell	PND28-Epithelial-Epithelial_Airway\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MNS1 CEP290 SPAG17 DNAI3	3.24e-04	187	78	4	f777dd5eb5ccd554ebe1ed60a738b5dd45e18bb9
ToppCell	tumor_Lung-Epithelial_cells-tS3\|Epithelial_cells / Location, Cell class and cell subclass	MNS1 ODAD4 SPAG17 DNAI3	3.24e-04	187	78	4	3cea677279e71fdb9879530dea10a5e6393beacd
ToppCell	Ciliated_cells-B-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	MNS1 ODAD4 SPAG17 DNAI3	3.24e-04	187	78	4	2b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MET DUOXA1 CACNA2D2 RAPGEF5	3.24e-04	187	78	4	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DNAJC25 RC3H1 CEP41 SEC14L1	3.24e-04	187	78	4	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DNAJC25 RC3H1 CEP41 SEC14L1	3.24e-04	187	78	4	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	facs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MNS1 ODAD4 SPAG17 DNAI3	3.24e-04	187	78	4	805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCell	Monocytes-M2-like_CD16+_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	SNX6 RB1 SPIRE1 NEB	3.24e-04	187	78	4	59e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCell	Ciliated_cells-B-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	MNS1 ODAD4 SPAG17 DNAI3	3.24e-04	187	78	4	bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	CMYA5 NEB DYSF EPHA5	3.31e-04	188	78	4	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CSNK2A1 ZMYM2 FMNL2 SEC14L1	3.31e-04	188	78	4	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	tumor_Lung-Epithelial_cells-tS3\|tumor_Lung / Location, Cell class and cell subclass	MNS1 ODAD4 SPAG17 DNAI3	3.31e-04	188	78	4	26326b4e298e33f9ba393fc632238aa8c54b1ea3
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CSNK2A1 ZMYM2 FMNL2 SEC14L1	3.31e-04	188	78	4	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	TTC28 RAPGEF5 ENPP2 SEC14L1	3.31e-04	188	78	4	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CSNK2A1 ZMYM2 FMNL2 SEC14L1	3.31e-04	188	78	4	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MNS1 ODAD4 SPAG17 DNAI3	3.31e-04	188	78	4	82c006f43c93f4a867953a446864f02b44536a23
ToppCell	Epithelial-Epithelial-D_(Ciliated)\|Epithelial / shred on cell class and cell subclass (v4)	MNS1 CEP290 ODAD4 SPAG17	3.31e-04	188	78	4	8f30535a32968a81a304315a49c0d90a77d36948
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	FBN1 IGF2R ZMYM2 CHD6	3.31e-04	188	78	4	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MNS1 ODAD4 SPAG17 DNAI3	3.31e-04	188	78	4	da59b5c0a4b11690a39a964c1a0a83e66aa0972b
ToppCell	droplet-Marrow-BM-30m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MNS1 GCLC SPIRE1 HARS1	3.31e-04	188	78	4	f1a9d8ea174a4bef0fae8188e3bd96b7ac1a39bb
ToppCell	Ciliated_cells-B-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	MNS1 GCLC SPAG17 DNAI3	3.31e-04	188	78	4	606907c865bd2f11bb6474932716550f7723d858
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-naive_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CERK SUCLG2 CDCA7L FKBP4	3.31e-04	188	78	4	1b349618f77260564486586b7f5a47a77d12859c
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	MNS1 ODAD4 SPAG17 DNAI3	3.31e-04	188	78	4	5ba5cbb403518026e9040379fb5d99339ea977d8
ToppCell	Striatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chodl_(Low-threshold_spiking_interneuron,_Npy+/Sst+)--\|Striatum / BrainAtlas - Mouse McCarroll V32	CCDC83 DUOXA1 NT5C1B	3.34e-04	77	78	3	7bb18406d404c51ee938cc577c155dc51868ddb9
ToppCell	Striatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chodl_(Low-threshold_spiking_interneuron,_Npy+/Sst+)\|Striatum / BrainAtlas - Mouse McCarroll V32	CCDC83 DUOXA1 NT5C1B	3.34e-04	77	78	3	ac311740424ff75b478b3c19fa0fae93776eb54e
ToppCell	Striatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chodl_(Low-threshold_spiking_interneuron,_Npy+/Sst+)-\|Striatum / BrainAtlas - Mouse McCarroll V32	CCDC83 DUOXA1 NT5C1B	3.34e-04	77	78	3	9f2dbf922acb905d636427a766a217c0db9671d2
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MNS1 ODAD4 SPAG17 DNAI3	3.38e-04	189	78	4	b55de812043b670cbde810d7d42f45909b6d66ef
ToppCell	PND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MNS1 CEP290 SPAG17 DNAI3	3.38e-04	189	78	4	fa1ff8b7fa53f3148d9117d6e598097f03af5eb2
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	MNS1 ODAD4 SPAG17 DNAI3	3.38e-04	189	78	4	dc440015949a768188c67661b6be63b1ead1a0f0
ToppCell	facs-Lung-24m-Epithelial-airway_epithelial-lung_ciliated_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MNS1 ODAD4 SPAG17 DNAI3	3.38e-04	189	78	4	1c28ad1263891d963e483b6847d8e89cc1b2d07e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MET TTC28 MTCL1 USH1C	3.38e-04	189	78	4	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	facs-Lung-24m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MNS1 ODAD4 SPAG17 DNAI3	3.38e-04	189	78	4	00b20c2ed7876486c8e42e3a5b13023f44987a34
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MNS1 GCLC CEP290 SPIRE1	3.38e-04	189	78	4	16dfc37d8d390ed7f927bc844c47c9c5a89a0928
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TTC28 RAPGEF5 ENPP2 DYSF	3.38e-04	189	78	4	6463890d8dbee4bc198f91628a5f784970de786a
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MNS1 GCLC CEP290 SPIRE1	3.38e-04	189	78	4	3ade3fa9369e85304b20d7233b581f18ad5ecc89
Drug	Salsolinol hydrobromide [38221-21-5]; Down 200; 15.4uM; MCF7; HT_HG-U133A	MET SWAP70 CEP41 BAZ1B IFIT5 ATM NEB JAKMIP2	2.87e-07	195	76	8	2791_DN
Drug	AC1NDTNH	RPGRIP1 GCLC ENPP2 CEP290 SMARCA1 NUP133 EXOC2 NAA50 SUCLG2	2.11e-06	343	76	9	CID004631409
Drug	Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; MCF7; HT_HG-U133A	A1CF SWAP70 RB1 ENPP2 KRT85 BAZ1B NEB	3.64e-06	192	76	7	2219_UP
Drug	pentachloronitrobenzene	MET GCLC FKBP4	1.27e-05	14	76	3	CID000006720
Drug	monomethyl phthalate	GBA3 CERK IGF2R SWAP70 SUPT5H CEP290 SMARCA1 NUP133 BAZ1B IFIT5 SMARCE1 TOP2B GSK3B	1.54e-05	957	76	13	ctd:C517284
Drug	ecdysone	MET FBN1 DUOXA1 RB1 NAA50 SEC14L1	2.92e-05	178	76	6	CID000019212
Drug	Phosphoaminophosphonic Acid-Adenylate Ester	CSNK2A1 TOP2B GSK3B	3.33e-05	19	76	3	DB04395
Drug	Dipyrone [5907-38-0]; Down 200; 12uM; PC3; HT_HG-U133A	MET CSNK2A1 ZMYM2 BAZ1B ATM SEC14L1	3.96e-05	188	76	6	4310_DN
Drug	Mepenzolate bromide [76-90-4]; Down 200; 9.6uM; PC3; HT_HG-U133A	MET CSNK2A1 ZMYM2 BAZ1B ATM SEC14L1	4.08e-05	189	76	6	4304_DN
Drug	Piracetam [7491-74-9]; Down 200; 28.2uM; MCF7; HT_HG-U133A	MET TTC28 PIK3R1 ZMYM2 BAZ1B SEC14L1	4.33e-05	191	76	6	2861_DN
Drug	Norgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; PC3; HT_HG-U133A	MET PIK3R1 CSNK2A1 CEP290 ZMYM2 SEC14L1	4.33e-05	191	76	6	4269_DN
Drug	Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; PC3; HT_HG-U133A	MET CEP290 ZMYM2 BAZ1B ATM SEC14L1	4.33e-05	191	76	6	4283_DN
Drug	Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; PC3; HT_HG-U133A	MET A1CF PIK3R1 ZMYM2 ATM SEC14L1	4.45e-05	192	76	6	4268_DN
Drug	aspirin, USP; Down 200; 100uM; HL60; HT_HG-U133A	RB1 PIK3R1 CSNK2A1 ZMYM2 BAZ1B ATM	4.45e-05	192	76	6	6164_DN
Drug	Sulmazole [73384-60-8]; Up 200; 14uM; MCF7; HT_HG-U133A	MET RAPGEF5 CSNK2A1 CEP290 ZMYM2 BAZ1B	5.00e-05	196	76	6	4127_UP
Drug	Yohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; MCF7; HT_HG-U133A	MET A1CF CACNA2D2 IFIT5 TTLL1 ATM	5.00e-05	196	76	6	2755_DN
Drug	Bambuterol hydrochloride [81732-46-9]; Down 200; 10uM; PC3; HT_HG-U133A	A1CF RAPGEF5 SUPT5H PIK3R1 ZMYM2 BAZ1B	5.29e-05	198	76	6	5885_DN
Drug	Proguanil hydrochloride [637-32-1]; Up 200; 13.8uM; MCF7; HT_HG-U133A	SWAP70 RB1 PIK3R1 ATM NEB JAKMIP2	5.29e-05	198	76	6	3505_UP
Drug	Etofylline [519-37-9]; Down 200; 17.8uM; MCF7; HT_HG-U133A	CACNA2D2 PIK3R1 CEP290 ZMYM2 BAZ1B IFIT5	5.29e-05	198	76	6	2256_DN
Drug	Levocabastine hydrochloride [79547-78-7]; Down 200; 8.8uM; MCF7; HT_HG-U133A	MET SWAP70 GALNT11 CEP290 TTLL1 MTCL1	5.44e-05	199	76	6	7009_DN
Drug	Acetopromazine maleate salt [3598-37-6]; Down 200; 9uM; MCF7; HT_HG-U133A	A1CF TTC28 SWAP70 BAZ1B IFIT5 TTLL1	5.44e-05	199	76	6	2769_DN
Drug	NSC226080	MET FBN1 IGF2R RB1 PIK3R1 CSNK2A1 ATM NAA50 HARS1 FKBP4 GSK3B	5.47e-05	782	76	11	CID000005040
Drug	3,5-dichloroaniline	ATM FKBP4	6.57e-05	4	76	2	CID000012281
Drug	gypenoside XVII	GBA3 RB1	6.57e-05	4	76	2	CID010373670
Drug	mixture of stereoisomers	GBA3 FKBP4	6.57e-05	4	76	2	CID000491684
Drug	dehydroilludin M	NAA50 TOP2B	6.57e-05	4	76	2	CID000168782
Drug	NSC105327	CDK9 GBA3 CDK16 GSK3B	8.89e-05	70	76	4	CID005318433
Drug	SU11274	MET RB1 GCLC	9.87e-05	27	76	3	CID009549297
Drug	dicyclohexyl phthalate	CDK9 GBA3 CERK IGF2R SWAP70 RC3H1 SMARCA1 IFIT5 SMARCE1 TOP2B GSK3B	9.93e-05	836	76	11	ctd:C036042
Drug	Akt inhibitor X	MET GSK3B	1.09e-04	5	76	2	CID010521421
Disease	glycocholate measurement	GCLC DYSF FMNL2	6.85e-05	30	78	3	EFO_0010491
Disease	Adenocarcinoma of large intestine	MET RIPK1 PIK3R1 ATM	1.25e-04	96	78	4	C1319315
Disease	Hereditary retinal dystrophy	ARL2BP USH1C	1.44e-04	7	78	2	C0154860
Disease	Usher syndrome	HARS1 USH1C	1.44e-04	7	78	2	cv:C0271097
Disease	hepatocellular carcinoma (biomarker_via_orthology)	MET RB1 PIK3R1 APRT	1.97e-04	108	78	4	DOID:684 (biomarker_via_orthology)
Disease	Ciliopathies	RPGRIP1 CEP290 CEP41 USH1C	2.11e-04	110	78	4	C4277690
Disease	Prostatic Neoplasms	MET IGF2R RB1 PIK3R1 SMARCA1 CHD6 ATM GSK3B	2.24e-04	616	78	8	C0033578
Disease	Malignant neoplasm of prostate	MET IGF2R RB1 PIK3R1 SMARCA1 CHD6 ATM GSK3B	2.24e-04	616	78	8	C0376358
Disease	HEPATOCELLULAR CARCINOMA	MET IGF2R	2.45e-04	9	78	2	114550
Disease	Hepatocellular carcinoma	MET IGF2R	2.45e-04	9	78	2	cv:C2239176
Disease	Disorder of eye	RPGRIP1 CEP290 CEP41 HARS1 USH1C	2.52e-04	212	78	5	C0015397
Disease	Major Depressive Disorder	RAPGEF5 CMYA5 APRT FKBP4 GSK3B	4.70e-04	243	78	5	C1269683
Disease	Coffin-Siris syndrome	SMARCA1 SMARCE1	5.28e-04	13	78	2	C0265338
Disease	Unipolar Depression	RAPGEF5 CMYA5 APRT FKBP4 GSK3B	6.28e-04	259	78	5	C0041696
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	MET ATM HARS1 APRT	6.50e-04	148	78	4	C0279702
Disease	Meckel-Gruber syndrome	RPGRIP1 CEP290	7.08e-04	15	78	2	C0265215
Disease	Neoplasm of uncertain or unknown behavior of bladder	RB1 ATM	7.08e-04	15	78	2	C0496930
Disease	Benign neoplasm of bladder	RB1 ATM	7.08e-04	15	78	2	C0154017
Disease	Carcinoma in situ of bladder	RB1 ATM	7.08e-04	15	78	2	C0154091
Disease	central nervous system disease (implicated_via_orthology)	SMARCA1 SEC31B	8.08e-04	16	78	2	DOID:331 (implicated_via_orthology)
Disease	Leber congenital amaurosis	RPGRIP1 CEP290	8.08e-04	16	78	2	cv:C0339527
Disease	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	ATM GSK3B	8.08e-04	16	78	2	C0334634
Disease	myeloid white cell count	MET TTC28 SWAP70 SUPT5H RC3H1 AKAP11 SPAG17 FMNL2 CDCA7L	8.11e-04	937	78	9	EFO_0007988
Disease	Benign neoplasm of stomach	MET ATM	9.14e-04	17	78	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	MET ATM	9.14e-04	17	78	2	C0496905
Disease	Carcinoma in situ of stomach	MET ATM	9.14e-04	17	78	2	C0154060
Disease	Carcinoma of bladder	RB1 ATM	1.03e-03	18	78	2	C0699885
Disease	Meckel syndrome type 1	RPGRIP1 CEP290	1.03e-03	18	78	2	C3714506
Disease	late-onset Alzheimers disease	RAPGEF5 CSNK2A1 ATM DYSF CDCA7L	1.07e-03	292	78	5	EFO_1001870
Disease	Familial aplasia of the vermis	CEP290 CEP41	1.27e-03	20	78	2	cv:C0431399
Disease	Stomach Carcinoma	MET ATM	1.40e-03	21	78	2	C0699791
Disease	Leber Congenital Amaurosis	RPGRIP1 CEP290	1.54e-03	22	78	2	C0339527
Disease	Neoplasm of the genitourinary tract	MET RB1	1.83e-03	24	78	2	cv:C0042065
Disease	Myocardial Infarction	GCLC ATM GSK3B	2.07e-03	95	78	3	C0027051
Disease	Hodgkins lymphoma, multiple myeloma, non-Hodgkins lymphoma	MNS1 EXOC2	2.49e-03	28	78	2	EFO_0000183, EFO_0001378, EFO_0005952
Disease	anterior thigh muscle fat infiltration measurement	PIK3R1 DYSF	2.49e-03	28	78	2	EFO_0020936
Disease	lung small cell carcinoma (is_implicated_in)	PIK3R1 ATM	2.49e-03	28	78	2	DOID:5409 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LIENDAEKDYLYDVL	USH1C	16	Q9Y6N9
VDGRKIYEQEGLEKY	NT5C1B	321	Q96P26
EEYLGKEEYLKEEEY	ERICH6B	71	Q5W0A0
KEEYLKEEEYLGKEE	ERICH6B	76	Q5W0A0
GKEGYLEKEDYIEEV	ERICH6B	141	Q5W0A0
LEKEDYIEEVDYLGK	ERICH6B	146	Q5W0A0
YIEEVDYLGKKAYLE	ERICH6B	151	Q5W0A0
DYLGKKAYLEEEEYL	ERICH6B	156	Q5W0A0
EEEYLGKKSYLEEEK	ERICH6B	166	Q5W0A0
QDNIKEEDIVYYDAK	CACNA2D2	151	Q9NY47
YQVKGDKREDKLYDI	A1CF	411	Q9NQ94
LHLIAYYKENKDRED	BAZ1B	476	Q9UIG0
NGIILEYEIKYFEKD	EPHA5	496	P54756
DLKKIEYYLEEEQGP	CEP41	306	Q9BYV8
YADGDEDYKVEEKLD	AKAP11	1291	Q9UKA4
DKYYLEFEDTEENKL	ARL2BP	46	Q9Y2Y0
ELLLVYDKDFKYGLN	DNAI3	101	Q8IWG1
LLYEDEKDFKDYVNL	CCDC83	351	Q8IWF9
YSLEYGKAELEIQKD	APRT	101	P07741
YEEIYLKNKDLDARL	RB1	321	P06400
YEEAKKCVEELALYL	RC3H1	96	Q5TC82
DELEQELQKYKSLYG	MTCL1	531	Q9Y4B5
GKLDYEEAKSYEIQV	PCDHA2	306	Q9Y5H9
YDFKKALDLLEYIDE	NUP133	1046	Q8WUM0
GYLEEELDYRKQALD	JAKMIP2	696	Q96AA8
QEVLEGYKKKYEEEV	KRT85	201	P78386
LYDLAKDAVEALYKV	CPA5	346	Q8WXQ8
YNDKFYKDVLEVGEL	NAA50	31	Q9GZZ1
YKDVLEVGELAKLAY	NAA50	36	Q9GZZ1
KGDYDVVINDYEKAK	EXOC2	296	Q96KP1
DDLKGELDEYVQKYL	GALNT11	196	Q8NCW6
EKYNDIDLTIDKEIY	GCLC	341	P48506
QEVLEGYKKKYEEEV	KRT87P	16	A6NCN2
YDNVKEYLESLQKEL	CDCA7L	436	Q96GN5
LYDYKKEREEDIDLH	PIK3R1	11	P27986
NIKGKEYGEEERLYI	DNAJC25	271	Q9H1X3
ILSVYLKGLDYENKD	ATM	2076	Q13315
KEKYGQLEEYLNFAD	CCDC82	521	Q8N4S0
KLEGEKRQAAEYYEK	IFIT5	446	Q13325
GIDYYNKIIDDLLKN	GBA3	96	Q9H227
LYYLKAEILGEAAEK	CHD6	1236	Q8TD26
EYLDKDLKQYLDDCG	CDK16	241	Q00536
KLDEKEQALYYARLE	CEP290	1241	O15078
ELNQLEDKYDKDYLS	FBN1	2841	P35555
AKETLYEINIDKYDG	CERK	176	Q8TCT0
FLYKDLYEEAVGEKK	CMYA5	3191	Q8N3K9
EKKDEVYLNLVLDYV	GSK3B	121	P49841
AKVLGTEDLYDYIDK	CSNK2A1	246	P68400
QYEFTKLGLDEYLDK	FMNL2	341	Q96PY5
DSQYGELIEKYIKEG	CMPK1	46	P30085
LLGELKYDFNEKDEF	FAM172BP	16	A6NC97
LKKGDFYQEDETDEY	FAM186A	441	A6NE01
EVALEGYYKDKLFDQ	FKBP4	171	Q02790
VDNYELYEKLELVKG	CDK9	256	P50750
ENYAEEYAKALEKGL	DUOXA1	136	Q1HG43
DDKLDADYIKRYLGD	SEC14L1	236	Q92503
TLYDYDLLSKDEKIG	DYSF	1646	O75923
KYGEDSKLIYDLKDQ	HARS1	106	P12081
YDYDGLHDTEDKIKQ	ENPP2	741	Q13822
YVLNEEDLQKVAEYK	MET	71	P08581
QYYLDLEKQLEEQEK	MNS1	186	Q8NEH6
DKTKYYLQDGDLDVV	IGF2R	2211	P11717
LAVRLEYGDNAEKYK	RTRAF	86	Q9Y224
LDEEKKECEEVGYAY	RPGRIP1	1216	Q96KN7
LYKFEGEDYREKQKL	SMARCA1	726	P28370
YVDLYVKDKLDETGV	TOP2B	291	Q02880
EKQEYLNEYEAEKIE	SMARCE1	111	Q969G3
LGELYVDKEYLEKLL	ODAD4	191	Q96NG3
DDVYEYPILEKELKE	RAPGEF5	181	Q92565
VDDLKYELEMYEKGL	MTG2	321	Q9H4K7
LKRGIYKDDIAQVDY	SUPT5H	281	O00267
KLEEAAQRLEYLYEK	SEC31B	1101	Q9NQW1
DHDYERDGLKEKVYQ	RIPK1	616	Q13546
IVKKEEKGDYYLEEE	SPAG17	1081	Q6Q759
LRGDQLFYYKDKDEI	ARHGAP22	61	Q7Z5H3
ENEAAKYDLKYIGLD	SUCLG2	286	Q96I99
EEEKKLLVYEALEYA	RMDN1	136	Q96DB5
IIIYKALDYGLKENE	SPIRE1	131	Q08AE8
ADEDLKLSDLLKYYL	SNX6	286	Q9UNH7
VKDIYDKDNYELDED	ZMYM2	1361	Q9UBW7
YYEQDLALAKDLHDK	TTC28	656	Q96AY4
YYVSEDLKDKKGDIL	SWAP70	241	Q9UH65
DYLDGKAVDYIEKAL	TTC37	686	Q6PGP7
YEEDYLVIDGIKLKA	ZCWPW2	321	Q504Y3
AEKDENGKYLYLDFV	TTLL1	96	O95922
RYSEKEKGEIELAEY	UNC79	1456	Q9P2D8
VNYSEKLYKLGLEEA	NEB	2751	P20929
LYKLALEESKKEGYD	NEB	3486	P20929