Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	RLF ZNF12 ZNF17 ZNF630 CTCFL SATB2 ZNF146 FEZF2 FEZF1 ZNF587 ZNF283 ZNF721 ZNF749 ZNF417 NKRF ZNF260 ZNF331 OVOL2	7.44e-07	1412	68	18	GO:0000981
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF12 ZNF17 ZNF630 CTCFL SATB2 ZNF146 FEZF2 FEZF1 MTOR ZNF587 ZNF283 ZNF721 ZNF417 NKRF ZNF260 ZNF331 OVOL2	8.40e-07	1271	68	17	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF12 ZNF17 ZNF630 CTCFL SATB2 ZNF146 FEZF2 FEZF1 ZNF587 ZNF283 ZNF721 ZNF417 NKRF ZNF260 ZNF331 OVOL2	3.15e-06	1244	68	16	GO:0000978
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF12 ZNF17 ZNF630 CTCFL SATB2 ZNF146 FEZF2 FEZF1 ZNF587 ZNF283 ZNF721 ZNF749 ZNF417 NKRF ZNF260 ZNF331 OVOL2	5.51e-06	1459	68	17	GO:0000977
GeneOntologyMolecularFunction	telomeric repeat-containing RNA binding	HNRNPA1L2 HNRNPA1	3.42e-05	3	68	2	GO:0061752
GeneOntologyMolecularFunction	RNA strand annealing activity	HNRNPA1L2 HNRNPA1	1.14e-04	5	68	2	GO:0033592
GeneOntologyMolecularFunction	miRNA binding	ZNF346 HNRNPA1L2 HNRNPA1	5.85e-04	48	68	3	GO:0035198
GeneOntologyMolecularFunction	G-rich strand telomeric DNA binding	HNRNPA1L2 HNRNPA1	6.16e-04	11	68	2	GO:0098505
GeneOntologyMolecularFunction	DNA/DNA annealing activity	HNRNPA1L2 HNRNPA1	6.16e-04	11	68	2	GO:1990814
GeneOntologyMolecularFunction	single-stranded telomeric DNA binding	HNRNPA1L2 HNRNPA1	8.70e-04	13	68	2	GO:0043047
GeneOntologyMolecularFunction	annealing activity	HNRNPA1L2 HNRNPA1	1.01e-03	14	68	2	GO:0140666
GeneOntologyMolecularFunction	sequence-specific single stranded DNA binding	HNRNPA1L2 HNRNPA1	1.17e-03	15	68	2	GO:0098847
GeneOntologyMolecularFunction	regulatory RNA binding	ZNF346 HNRNPA1L2 HNRNPA1	1.24e-03	62	68	3	GO:0061980
GeneOntologyMolecularFunction	sequence-specific mRNA binding	HNRNPA1L2 HNRNPA1	1.88e-03	19	68	2	GO:1990825
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	RLF CTCFL SATB2 FEZF2 ZNF721 NKRF OVOL2	2.90e-03	560	68	7	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	RLF CTCFL SATB2 FEZF2 ZNF721 NKRF OVOL2	3.08e-03	566	68	7	GO:0001216
GeneOntologyCellularComponent	nucleoplasmic periphery of the nuclear pore complex	HNRNPA1L2 HNRNPA1	1.60e-04	6	69	2	GO:1990826
GeneOntologyCellularComponent	catalytic step 2 spliceosome	HNRNPA3 HNRNPA1L2 HNRNPA1 HNRNPA1L3	2.99e-04	97	69	4	GO:0071013
MousePheno	tongue muscle hypoplasia	HNRNPA1L2 HNRNPA1	1.31e-05	2	51	2	MP:0030421
Domain	Znf_C2H2-like	RLF ZNF12 ZMAT3 ZNF17 ZNF346 ZNF630 CTCFL ZNF146 PHF20 ZNF608 FEZF2 FEZF1 ZNF587 ZNF283 ZNF721 ZNF749 ZMAT4 ZNF318 ZNF417 ZNF260 ZNF331 OVOL2	1.14e-14	796	65	22	IPR015880
Domain	ZnF_C2H2	RLF ZNF12 ZMAT3 ZNF17 ZNF346 ZNF630 CTCFL ZNF146 PHF20 ZNF608 FEZF2 FEZF1 ZNF587 ZNF283 ZNF721 ZNF749 ZMAT4 ZNF318 ZNF417 ZNF260 ZNF331 OVOL2	1.55e-14	808	65	22	SM00355
Domain	Znf_C2H2	RLF ZNF12 ZNF17 ZNF346 ZNF630 CTCFL ZNF146 PHF20 ZNF608 FEZF2 FEZF1 ZNF587 ZNF283 ZNF721 ZNF749 ZMAT4 ZNF417 ZNF260 ZNF331 OVOL2	1.76e-12	805	65	20	IPR007087
Domain	ZINC_FINGER_C2H2_2	RLF ZNF12 ZNF17 ZNF630 CTCFL ZNF146 PHF20 ZNF608 FEZF2 FEZF1 ZNF587 ZNF283 ZNF721 ZNF749 ZNF417 ZNF260 ZNF331 OVOL2	8.70e-11	775	65	18	PS50157
Domain	ZINC_FINGER_C2H2_1	RLF ZNF12 ZNF17 ZNF630 CTCFL ZNF146 PHF20 ZNF608 FEZF2 FEZF1 ZNF587 ZNF283 ZNF721 ZNF749 ZNF417 ZNF260 ZNF331 OVOL2	9.08e-11	777	65	18	PS00028
Domain	zf-C2H2	RLF ZNF12 ZNF17 ZNF630 CTCFL ZNF146 PHF20 FEZF2 FEZF1 ZNF587 ZNF283 ZNF721 ZNF749 ZNF417 ZNF260 ZNF331 OVOL2	1.39e-10	693	65	17	PF00096
Domain	-	RLF ZNF12 ZNF17 ZNF630 CTCFL ZNF146 FEZF2 FEZF1 ZNF587 ZNF283 ZNF721 ZNF749 ZNF417 ZNF260 ZNF331 OVOL2	9.63e-10	679	65	16	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	RLF ZNF12 ZNF17 ZNF630 CTCFL ZNF146 FEZF2 FEZF1 ZNF587 ZNF283 ZNF721 ZNF749 ZNF417 ZNF260 ZNF331 OVOL2	1.32e-09	694	65	16	IPR013087
Domain	zf-C2H2_6	ZNF12 ZNF17 FEZF2 FEZF1 ZNF587 ZNF283 ZNF721 ZNF749 ZNF417 ZNF260 ZNF331	1.02e-08	314	65	11	PF13912
Domain	ZF_MATRIN	ZMAT3 ZNF346 ZMAT4 ZNF318	3.94e-07	18	65	4	PS50171
Domain	ZnF_U1	ZMAT3 ZNF346 ZMAT4 ZNF318	2.97e-06	29	65	4	SM00451
Domain	Znf_U1	ZMAT3 ZNF346 ZMAT4 ZNF318	2.97e-06	29	65	4	IPR003604
Domain	KRAB	ZNF12 ZNF17 ZNF630 ZNF587 ZNF283 ZNF749 ZNF417 ZNF331	3.28e-05	358	65	8	PS50805
Domain	KRAB	ZNF12 ZNF17 ZNF630 ZNF587 ZNF283 ZNF749 ZNF417 ZNF331	3.28e-05	358	65	8	PF01352
Domain	HnRNPA1	HNRNPA1L2 HNRNPA1	3.57e-05	3	65	2	PF11627
Domain	HnRNPA1	HNRNPA1L2 HNRNPA1	3.57e-05	3	65	2	IPR021662
Domain	KRAB	ZNF12 ZNF17 ZNF630 ZNF587 ZNF283 ZNF749 ZNF417 ZNF331	4.07e-05	369	65	8	SM00349
Domain	KRAB	ZNF12 ZNF17 ZNF630 ZNF587 ZNF283 ZNF749 ZNF417 ZNF331	4.15e-05	370	65	8	IPR001909
Domain	Znf_C2H2_matrin	ZNF346 ZNF318	7.70e-04	12	65	2	IPR000690
Domain	Znf_C2H2_jaz	ZMAT3 ZMAT4	2.63e-03	22	65	2	IPR022755
Domain	zf-C2H2_jaz	ZMAT3 ZMAT4	2.63e-03	22	65	2	PF12171
Domain	Myosin_head_motor_dom	MYO1A MYO15A	7.73e-03	38	65	2	IPR001609
Domain	MYOSIN_MOTOR	MYO1A MYO15A	7.73e-03	38	65	2	PS51456
Domain	Myosin_head	MYO1A MYO15A	7.73e-03	38	65	2	PF00063
Domain	MYSc	MYO1A MYO15A	7.73e-03	38	65	2	SM00242
Domain	-	RC3H2 ZC3H6	8.54e-03	40	65	2	4.10.1000.10
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	RLF ZNF12 ZNF146 LMAN2L ZNF608 ZNF283 HNRNPA3 LRPAP1 NSMCE2 RAB21 ZNF417 HNRNPA1 ZNF260	6.08e-07	1203	69	13	29180619
Pubmed	Fez family transcription factors: controlling neurogenesis and cell fate in the developing mammalian nervous system.	FEZF2 FEZF1	3.88e-06	2	69	2	24913420
Pubmed	Post-translational modifications of hnRNP A1 differentially modulate retroviral IRES-mediated translation initiation.	HNRNPA1L2 HNRNPA1	3.88e-06	2	69	2	32960212
Pubmed	siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.	HNRNPA1L2 HNRNPA1	3.88e-06	2	69	2	15215364
Pubmed	Phosphorylation of hnRNP A1-Serine 199 Is Not Required for T Cell Differentiation and Function.	HNRNPA1L2 HNRNPA1	3.88e-06	2	69	2	38334757
Pubmed	Retroviral insertions downstream of the heterogeneous nuclear ribonucleoprotein A1 gene in erythroleukemia cells: evidence that A1 is not essential for cell growth.	HNRNPA1L2 HNRNPA1	3.88e-06	2	69	2	1406633
Pubmed	dFezf/Earmuff maintains the restricted developmental potential of intermediate neural progenitors in Drosophila.	FEZF2 FEZF1	3.88e-06	2	69	2	20152183
Pubmed	Heterogeneous nuclear ribonucleoprotein A1 regulates rhythmic synthesis of mouse Nfil3 protein via IRES-mediated translation.	HNRNPA1L2 HNRNPA1	3.88e-06	2	69	2	28220845
Pubmed	The zinc finger-only protein Zfp260 is a novel cardiac regulator and a nuclear effector of alpha1-adrenergic signaling.	ZNF146 ZNF260	3.88e-06	2	69	2	16166646
Pubmed	An Hdac1/Rpd3-Poised Circuit Balances Continual Self-Renewal and Rapid Restriction of Developmental Potential during Asymmetric Stem Cell Division.	FEZF2 FEZF1	3.88e-06	2	69	2	28245922
Pubmed	Novel Pathological Role of hnRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1) in Vascular Smooth Muscle Cell Function and Neointima Hyperplasia.	HNRNPA1L2 HNRNPA1	3.88e-06	2	69	2	28912364
Pubmed	hnRNP A1 dysfunction in oligodendrocytes contributes to the pathogenesis of multiple sclerosis.	HNRNPA1L2 HNRNPA1	3.88e-06	2	69	2	36382566
Pubmed	mTOR Activation Underlies Enhanced B Cell Proliferation and Autoimmunity in PrkcdG510S/G510S Mice.	MTOR PRKCD	3.88e-06	2	69	2	36961448
Pubmed	Zfp312 is required for subcortical axonal projections and dendritic morphology of deep-layer pyramidal neurons of the cerebral cortex.	FEZF2 FEZF1	3.88e-06	2	69	2	16314561
Pubmed	Loss of hnRNP A1 in murine skeletal muscle exacerbates high-fat diet-induced onset of insulin resistance and hepatic steatosis.	HNRNPA1L2 HNRNPA1	3.88e-06	2	69	2	31169879
Pubmed	Regulation of mouse hepatitis virus RNA synthesis by heterogeneous nuclear ribonucleoprotein A1.	HNRNPA1L2 HNRNPA1	3.88e-06	2	69	2	11774503
Pubmed	Role of hnRNP A1 in coronavirus RNA synthesis.	HNRNPA1L2 HNRNPA1	3.88e-06	2	69	2	11774505
Pubmed	Cloning, characterization, and chromosome assignment of Zfp146 the mouse ortholog of human ZNF146, a gene amplified and overexpressed in pancreatic cancer, and Zfp260 a closely related gene.	ZNF146 ZNF260	3.88e-06	2	69	2	10449921
Pubmed	The A1 and A1B proteins of heterogeneous nuclear ribonucleoparticles modulate 5' splice site selection in vivo.	HNRNPA1L2 HNRNPA1	3.88e-06	2	69	2	8041722
Pubmed	Interplay between hnRNP A1 and a cis-acting element in the 3' UTR of CYP2A5 mRNA is central for high expression of the gene.	HNRNPA1L2 HNRNPA1	3.88e-06	2	69	2	12560094
Pubmed	Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs.	HNRNPA3 HNRNPA1L2 HNRNPA1	1.12e-05	22	69	3	12456657
Pubmed	Analysis of hnRNPA1, A2/B1, and A3 genes in patients with amyotrophic lateral sclerosis.	HNRNPA3 HNRNPA1	1.16e-05	3	69	2	23827524
Pubmed	Heterogeneous Nuclear Ribonucleoprotein A1 Improves the Intestinal Injury by Regulating Apoptosis Through Trefoil Factor 2 in Mice with Anti-CD3-induced Enteritis.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	25901972
Pubmed	Phosphomimetic substitution of heterogeneous nuclear ribonucleoprotein A1 at serine 199 abolishes AKT-dependent internal ribosome entry site-transacting factor (ITAF) function via effects on strand annealing and results in mammalian target of rapamycin complex 1 (mTORC1) inhibitor sensitivity.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	21454539
Pubmed	PRMT5 regulates IRES-dependent translation via methylation of hnRNP A1.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	28115626
Pubmed	Adipocyte-Specific Hnrnpa1 Knockout Aggravates Obesity-Induced Metabolic Dysfunction via Upregulation of CCL2.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	38320300
Pubmed	HnRNP A1 Suppresses the Odontogenic Differentiation and the Inclusion of RUNX2 Exon 5 of Dental Mesenchymal Cells.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	37525910
Pubmed	Lipid signalling drives proteolytic rewiring of mitochondria by YME1L.	LPIN1 MTOR	1.16e-05	3	69	2	31695197
Pubmed	HuR-regulated mRNAs associated with nuclear hnRNP A1-RNP complexes.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	24152440
Pubmed	Relative amounts of antagonistic splicing factors, hnRNP A1 and ASF/SF2, change during neoplastic lung growth: implications for pre-mRNA processing.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	15390079
Pubmed	HNRNPA1-mediated exosomal sorting of miR-483-5p out of renal tubular epithelial cells promotes the progression of diabetic nephropathy-induced renal interstitial fibrosis.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	33692334
Pubmed	The Splicing Factor hnRNPA1 Regulates Alternate Splicing of the MYLK Gene.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	29077485
Pubmed	Molecular cloning of the genes suppressed in RVC lymphoma cells by topoisomerase inhibitors.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	8912629
Pubmed	A widespread sequence-specific mRNA decay pathway mediated by hnRNPs A1 and A2/B1.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	27151978
Pubmed	Resveratrol limits epithelial to mesenchymal transition through modulation of KHSRP/hnRNPA1-dependent alternative splicing in mammary gland cells.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	28088441
Pubmed	eIF2alpha phosphorylation tips the balance to apoptosis during osmotic stress.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	20338999
Pubmed	Stimulation of signal transducer and activator of transcription-1 (STAT1)-dependent gene transcription by lipopolysaccharide and interferon-gamma is regulated by mammalian target of rapamycin.	MTOR PRKCD	1.16e-05	3	69	2	12807916
Pubmed	Quaking regulates Hnrnpa1 expression through its 3' UTR in oligodendrocyte precursor cells.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	21253564
Pubmed	LncRNAH19 improves insulin resistance in skeletal muscle by regulating heterogeneous nuclear ribonucleoprotein A1.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	33115498
Pubmed	hnRNP A1 and secondary structure coordinate alternative splicing of Mag.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	23704325
Pubmed	Phosphorylation of lipin 1 and charge on the phosphatidic acid head group control its phosphatidic acid phosphatase activity and membrane association.	LPIN1 MTOR	1.16e-05	3	69	2	23426360
Pubmed	Norovirus genome circularization and efficient replication are facilitated by binding of PCBP2 and hnRNP A1.	HNRNPA1L2 HNRNPA1	1.16e-05	3	69	2	23946460
Pubmed	Involvement of hnRNP A1 in the matrix metalloprotease-3-dependent regulation of Rac1 pre-mRNA splicing.	HNRNPA1L2 HNRNPA1	2.32e-05	4	69	2	22345078
Pubmed	Irisin ameliorates endoplasmic reticulum stress and liver fibrosis through inhibiting PERK-mediated destabilization of HNRNPA1 in hepatic stellate cells.	HNRNPA1L2 HNRNPA1	2.32e-05	4	69	2	33951764
Pubmed	ALS-linked mutations in ubiquilin-2 or hnRNPA1 reduce interaction between ubiquilin-2 and hnRNPA1.	HNRNPA3 HNRNPA1	2.32e-05	4	69	2	25616961
Pubmed	m6A-Induced lncRNA MEG3 Promotes Cerebral Ischemia-Reperfusion Injury Via Modulating Oxidative Stress and Mitochondrial Dysfunction by hnRNPA1/Sirt2 Axis.	HNRNPA1L2 HNRNPA1	2.32e-05	4	69	2	38358439
Pubmed	Analysis of RNA-protein interactions of mouse liver cytochrome P4502A5 mRNA.	HNRNPA1L2 HNRNPA1	2.32e-05	4	69	2	10215609
Pubmed	hnRNP Q and hnRNP A1 Regulate the Translation of Cofilin in Response to Transient Oxygen-Glucose Deprivation in Hippocampal Neurons.	HNRNPA1L2 HNRNPA1	2.32e-05	4	69	2	34944075
Pubmed	Synthetic modified Fezf2 mRNA (modRNA) with concurrent small molecule SIRT1 inhibition enhances refinement of cortical subcerebral/corticospinal neuron identity from mouse embryonic stem cells.	SATB2 FEZF2	2.32e-05	4	69	2	34473715
Pubmed	Decrease in hnRNP A/B expression during erythropoiesis mediates a pre-mRNA splicing switch.	HNRNPA1L2 HNRNPA1	2.32e-05	4	69	2	12426391
Pubmed	hnRNPA1 SUMOylation promotes cold hypersensitivity in chronic inflammatory pain by stabilizing TRPA1 mRNA.	HNRNPA1L2 HNRNPA1	2.32e-05	4	69	2	37943660
Pubmed	Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation.	MTOR PRKCD	2.32e-05	4	69	2	10698949
Pubmed	Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice.	MTOR HNRNPA1L2 HNRNPA1	2.92e-05	30	69	3	28077597
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZMAT3 ZNF346 SATB2 PHF20 ZNF721 ZNF318 ZC3H6 ZNF260 OVOL2	3.08e-05	808	69	9	20412781
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF17 ZNF587 ZNF721 ZNF749 ZNF417	3.10e-05	181	69	5	37372979
Pubmed	Impact of heterogeneous nuclear ribonucleoprotein A/B subtype overexpression on the expression of cancer stem cell markers CD133 and CD44 and cellular proliferation capacity.	HNRNPA1L2 HNRNPA1	3.86e-05	5	69	2	38279469
Pubmed	cDNA cloning of human hnRNP protein A1 reveals the existence of multiple mRNA isoforms.	HNRNPA1 HNRNPA1L3	3.86e-05	5	69	2	2836799
Pubmed	Heterogeneous nuclear ribonucleoprotein A1 regulates cyclin D1 and c-myc internal ribosome entry site function through Akt signaling.	HNRNPA1L2 HNRNPA1	3.86e-05	5	69	2	18562319
Pubmed	The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism.	HNRNPA1L2 HNRNPA1	3.86e-05	5	69	2	20133837
Pubmed	Caveolin1 Identifies a Specific Subpopulation of Cerebral Cortex Callosal Projection Neurons (CPN) Including Dual Projecting Cortical Callosal/Frontal Projection Neurons (CPN/FPN).	SATB2 FEZF2	3.86e-05	5	69	2	29379878
Pubmed	7SK small nuclear ribonucleoprotein complex is recruited to the HIV-1 promoter via short viral transcripts.	HNRNPA1L2 HNRNPA1	3.86e-05	5	69	2	24607481
Pubmed	Identification of novel cellular genes transcriptionally suppressed by v-src.	HNRNPA1L2 HNRNPA1	5.79e-05	6	69	2	7832805
Pubmed	Stella is a maternal effect gene required for normal early development in mice.	HNRNPA1L2 HNRNPA1	5.79e-05	6	69	2	14654002
Pubmed	Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1.	MTOR LRPAP1	8.09e-05	7	69	2	16798736
Pubmed	HNRNPA1-induced spliceopathy in a transgenic mouse model of myotonic dystrophy.	HNRNPA1L2 HNRNPA1	8.09e-05	7	69	2	32086392
Pubmed	Myosins: a diverse superfamily.	MYO1A MYO15A	8.09e-05	7	69	2	10722873
Pubmed	Comparative proteomic analysis to study molecular events during gonad development in mice.	HNRNPA1L2 HNRNPA1	8.09e-05	7	69	2	16604525
Pubmed	Protein kinase C-delta and phosphatidylinositol 3-kinase/Akt activate mammalian target of rapamycin to modulate NF-kappaB activation and intercellular adhesion molecule-1 (ICAM-1) expression in endothelial cells.	MTOR PRKCD	8.09e-05	7	69	2	19074768
Pubmed	Isolation of epiblast-specific cDNA clones by differential hybridization with polymerase chain reaction-amplified probes derived from single embryos.	HNRNPA1L2 HNRNPA1	8.09e-05	7	69	2	1497882
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	LPIN1 RESF1 FEZF1 AZIN2 NKRF	1.02e-04	233	69	5	37704626
Pubmed	hnRNP A1B, a Splice Variant of HNRNPA1, Is Spatially and Temporally Regulated.	HNRNPA1L2 HNRNPA1	1.08e-04	8	69	2	34630013
Pubmed	Inactivation of mammalian target of rapamycin increases STAT1 nuclear content and transcriptional activity in alpha4- and protein phosphatase 2A-dependent fashion.	MTOR PRKCD	1.08e-04	8	69	2	19553685
Pubmed	Genome-wide target analysis of NEUROD2 provides new insights into regulation of cortical projection neuron migration and differentiation.	SATB2 FEZF2	1.08e-04	8	69	2	26341353
Pubmed	RNA association and nucleocytoplasmic shuttling by ataxin-1.	HNRNPA1L2 HNRNPA1	1.08e-04	8	69	2	15615787
Pubmed	Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells.	RC3H2 MTOR	1.08e-04	8	69	2	29246441
Pubmed	Neurog2 Acts as a Classical Proneural Gene in the Ventromedial Hypothalamus and Is Required for the Early Phase of Neurogenesis.	SATB2 FEZF1	1.08e-04	8	69	2	32273485
Pubmed	Association of atypical protein kinase C isotypes with the docker protein FRS2 in fibroblast growth factor signaling.	PRKCD HNRNPA1	1.08e-04	8	69	2	10383403
Pubmed	Human transcription factor protein interaction networks.	RLF SATB2 ZNF146 RESF1 ZNF608 DLD ZNF721 ZNF318 HERC1 NKRF ZNF260	1.11e-04	1429	69	11	35140242
Pubmed	Distinct class of putative "non-conserved" promoters in humans: comparative studies of alternative promoters of human and mouse genes.	RESF1 ZNF749 RFWD3	1.29e-04	49	69	3	17567985
Pubmed	Fezf1 and Fezf2 are required for olfactory development and sensory neuron identity.	FEZF2 FEZF1	1.38e-04	9	69	2	21452247
Pubmed	A network of genetic repression and derepression specifies projection fates in the developing neocortex.	SATB2 FEZF2	1.38e-04	9	69	2	23144223
Pubmed	Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins.	ZNF17 AZIN2 ZNF721	1.45e-04	51	69	3	11853319
Pubmed	Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network.	HNRNPA3 HNRNPA1L2 HNRNPA1	1.54e-04	52	69	3	26265008
Pubmed	The RNA recognition motif protein RBM11 is a novel tissue-specific splicing regulator.	HNRNPA1L2 HNRNPA1	1.73e-04	10	69	2	21984414
Pubmed	Mutual regulation between Satb2 and Fezf2 promotes subcerebral projection neuron identity in the developing cerebral cortex.	SATB2 FEZF2	1.73e-04	10	69	2	26324926
Pubmed	Dynamics of cortical progenitors and production of subcerebral neurons are altered in embryos of a maternal inflammation model for autism.	SATB2 FEZF2	1.73e-04	10	69	2	31740755
Pubmed	PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12.	MTOR PRKCD	1.73e-04	10	69	2	22609986
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RLF SATB2 RESF1 KIF15 ZNF608 ZNF318	1.84e-04	418	69	6	34709266
Pubmed	Aerocyte specification and lung adaptation to breathing is dependent on alternative splicing changes.	HNRNPA1L2 HNRNPA1	2.11e-04	11	69	2	36220570
Pubmed	Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.	ZNF608 CCDC146 GNPDA2	2.13e-04	58	69	3	20935630
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	PHF20 MTOR HNRNPA3 DLD PRKCD HNRNPA1L2 HNRNPA1	2.32e-04	621	69	7	22794259
Pubmed	Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.	MTOR WNK3	2.53e-04	12	69	2	27782176
Pubmed	A novel SR-related protein is required for the second step of Pre-mRNA splicing.	HNRNPA1L2 HNRNPA1	2.53e-04	12	69	2	15798186
Pubmed	Satb2 Regulates the Differentiation of Both Callosal and Subcerebral Projection Neurons in the Developing Cerebral Cortex.	SATB2 FEZF2	2.53e-04	12	69	2	25037921
Pubmed	The activity of the spinal muscular atrophy protein is regulated during development and cellular differentiation.	HNRNPA1L2 HNRNPA1	2.53e-04	12	69	2	16236758
Pubmed	The biogenesis of the coiled body during early mouse development.	HNRNPA1L2 HNRNPA1	2.53e-04	12	69	2	7768196
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	LMAN2L HNRNPA3 HERC1 NKRF RFWD3	2.61e-04	285	69	5	32838362
Pubmed	Zbtb20 defines a hippocampal neuronal identity through direct repression of genes that control projection neuron development in the isocortex.	SATB2 FEZF2	2.98e-04	13	69	2	23283686
Pubmed	Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.	HNRNPA1L2 HNRNPA1	2.98e-04	13	69	2	28024152
Pubmed	The zinc finger gene Fezf2 is required for the development of excitatory neurons in the basolateral complex of the amygdala.	FEZF2 FEZF1	2.98e-04	13	69	2	24723342
Interaction	OR9Q2 interactions	HNRNPA3 HNRNPA1L2 HNRNPA1	3.50e-07	5	67	3	int:OR9Q2
Interaction	FCMR interactions	HNRNPA3 HNRNPA1L2 HNRNPA1	5.69e-06	11	67	3	int:FCMR
Interaction	LTBP2 interactions	ZNF12 ZNF17 ZNF749 ZNF417 ZNF260	9.32e-06	85	67	5	int:LTBP2
Interaction	EPX interactions	HNRNPA3 HNRNPA1L2 HNRNPA1	1.91e-05	16	67	3	int:EPX
Cytoband	19q13.43	ZNF587 ZNF749 ZNF417	3.15e-04	87	69	3	19q13.43
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF17 ZNF146 ZNF587 ZNF283 ZNF749 ZNF417 ZNF260 ZNF331	4.15e-04	1192	69	8	chr19q13
Cytoband	1p35.1	AZIN2 TMEM39B	1.07e-03	32	69	2	1p35.1
Cytoband	Ensembl 112 genes in cytogenetic band chrXp11	EFHC2 ZNF630 ITIH6 WNK3	2.54e-03	377	69	4	chrXp11
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	RLF ZNF12 ZNF17 ZNF630 CTCFL ZNF146 ZNF608 FEZF2 FEZF1 ZNF587 ZNF283 ZNF721 ZNF749 ZNF318 ZNF417 ZNF260 ZNF331 OVOL2	1.17e-13	718	48	18	28
GeneFamily	Zinc fingers CCCH-type\|Zinc fingers matrin-type	ZMAT3 ZMAT4	6.87e-05	5	48	2	84
GeneFamily	Zinc fingers CCCH-type	RC3H2 ZC3H6	3.88e-03	35	48	2	73
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000	SATB2 SYCP2 LMAN2L ZNF318 HERC1 ZC3H6	2.35e-07	85	65	6	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k1_1000
CoexpressionAtlas	ratio_EmbryoidBody-blastocyst_vs_EmbryoidBody-fibro_top-relative-expression-ranked_2500_k-means-cluster#2	TLCD3B RESF1 ZNF608 FEZF1 ZMAT4 WNK3 RFWD3 ZNF331 OVOL2	2.63e-06	387	65	9	ratio_EB-blastocyst_vs_EB-fibro_2500_K2
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_1000	SATB2 SYCP2 ZNF318 HERC1 ZC3H6	2.20e-05	110	65	5	gudmap_dev gonad_e13.5_M_GermCell_Oct_k4_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	SATB2 SYCP2 LMAN2L LACC1 MTOR ZNF318 HERC1 ZC3H6 NKRF WNK3 RFWD3	3.54e-05	820	65	11	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
Disease	myopathy (implicated_via_orthology)	HNRNPA3 HNRNPA1L2 HNRNPA1 HNRNPA1L3	3.42e-06	48	63	4	DOID:423 (implicated_via_orthology)
Disease	neurodegenerative disease (implicated_via_orthology)	HNRNPA3 HNRNPA1L2 HNRNPA1 HNRNPA1L3 MTMR10	1.49e-05	145	63	5	DOID:1289 (implicated_via_orthology)
Disease	dihydrolipoyl dehydrogenase, mitochondrial measurement	FAM3A DLD	2.68e-05	4	63	2	EFO_0802466
Disease	autosomal dominant limb-girdle muscular dystrophy type 3 (implicated_via_orthology)	HNRNPA3 HNRNPA1	6.69e-05	6	63	2	DOID:0110306 (implicated_via_orthology)
Disease	behavior	FAM3A DLD ZMAT4	2.25e-04	55	63	3	GO_0007610
Disease	Toxic Encephalitis	MTOR PRKCD	1.76e-03	29	63	2	C0154659
Disease	Neurotoxicity Syndromes	MTOR PRKCD	1.76e-03	29	63	2	C0235032
Disease	Encephalopathy, Toxic	MTOR PRKCD	1.76e-03	29	63	2	C0149504
Disease	Large cell carcinoma of lung	MTOR WNK3	2.14e-03	32	63	2	C0345958
Disease	sensorineural hearing loss (is_implicated_in)	MYO1A MYO15A	2.27e-03	33	63	2	DOID:10003 (is_implicated_in)
Disease	Antihypertensive use measurement	PLEKHG1 LRPAP1 PRKCD ZNF318	2.50e-03	265	63	4	EFO_0009927
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	LMAN2L MTOR WNK3	3.94e-03	148	63	3	C0279702

Protein segments in the cluster

Peptide	Gene	Start	Entry
DHQNFVKVRNKHKGK	CCDC112	171	Q8NEF3
YALIQHQKTHKNEKR	CTCFL	471	Q8NI51
KQIAQIKYAAKHGIQ	AZIN2	116	Q96A70
KLCAHYQQSGKHNKK	GPR15	221	P49685
QIQTFFHKHLNGKKS	ACOT6	401	Q3I5F7
AKIEKHNHYQKQLEI	LRPAP1	286	P30533
HQSIKLSNLGENKHY	RC3H2	81	Q9HBD1
KIVIQKYHTVKGHNC	HNRNPA1L2	161	Q32P51
KIVIQKYHTVNGHNC	HNRNPA1L3	116	A0A2R8Y4L2
AKHYHTSAKQNKGIE	RAB21	156	Q9UL25
PSSQGQHKHKYHFQK	RFWD3	426	Q6PCD5
GKLVGHQNLHQKIQY	KIF15	1341	Q9NS87
VGKKYHNSANKINGI	MTMR10	181	Q9NXD2
GAIKQAKIHYIKNHE	PRKCD	146	Q05655
GKVTYQVHKFLDKNH	MYO15A	1706	Q9UKN7
KLNQLFSKHGHYESK	MYO1A	471	Q9UBC5
YHDKGKVKQQQHSPE	HERC1	121	Q15751
FNRNVGKEKFHKSQH	EFHC2	11	Q5JST6
NHYVKAVQSTINHVK	NSMCE2	76	Q96MF7
KTLNAVQYHHAAKAK	LACC1	26	Q8IV20
THQGIAKLYHKVSQN	LPIN1	701	Q14693
LQVHFKIHGQGKKNL	LMAN2L	111	Q9H0V9
ESHLKKIHGVQQQYA	OVOL2	191	Q9BRP0
PFEQHVKNSKHSNKY	FAM3A	196	P98173
YNEKHHQQKVKLQKV	CCDC30	501	Q5VVM6
LFKQNKVVHVNGYGK	DLD	141	P09622
HKNGHLSFKYVKTFN	GNPDA2	56	Q8TDQ7
HQAKKIYEEAHQQGK	ITIH6	101	Q6UXX5
HQKGNYKNHKLTHSG	FEZF2	371	Q8TBJ5
KQYVIKHQNTHTGEK	ZNF146	56	Q15072
GQKKYLIKHQNIHTG	ZNF146	166	Q15072
YSHQNAKKIVATHQL	PHF20	731	Q9BVI0
VLHYKHQNQARDEKK	MTOR	1801	P42345
IHQIAQKYGLKSKSH	NKRF	636	O15226
QKGYHHRTELNKKIF	RPL3L	271	Q92901
GKNLKIHHSQESKTY	RESF1	1516	Q9HCM1
KGFHQKGNYKNHKLT	FEZF1	351	A0PJY2
QQKKIESYLHNHFIG	TENT5D	276	Q8NEK8
KFFQNQRYHVKHHGK	SATB2	661	Q9UPW6
QHYFGQKDQQHTKSK	SEMG2	46	Q02383
YAGHQLQQIMEHKKS	SNUPN	301	O95149
NKFVNLLHKAHQKVN	CCDC146	526	Q8IYE0
GHDQKKKYVFQLTHD	CNKSR1	461	Q969H4
AAGNMVHVKQKLYHN	TMEM240	151	Q5SV17
NQHTVEHKGKQICKY	ZC3H6	266	P61129
GKAFSLKHNVVQHLK	ZNF749	416	O43361
KQYLIKHQNIHTGKK	ZNF260	176	Q3ZCT1
YKNKHQIGSDRATHK	RLF	1191	Q13129
KKHNQQQNHPKYSGQ	SYCP2	691	Q9BX26
HQHQKQHIGEKFYRK	ZNF587	136	Q96SQ5
YTALNQHKKIHTGEK	ZNF721	361	Q8TF20
HQHQKQHIGEKFYRK	ZNF417	136	Q8TAU3
VNYLTQHQKIHTGEK	ZNF331	311	Q9NQX6
DKIVVQKYHTINGHN	HNRNPA3	181	P51991
QKYHTINGHNCEVKK	HNRNPA3	186	P51991
HKQAHVQYKKFQARE	ZNF630	246	Q2M218
SQKLAHYQSKKHANK	ZNF346	86	Q9UL40
QQHYVGKKHRKQETK	ZNF346	201	Q9UL40
NKKYKHINGLRYHQA	ZNF608	561	Q9ULD9
YKQQHTLLHKVNGAL	TLCD3B	181	Q71RH2
QAHYQGKNHGKKLRN	ZMAT3	86	Q9HA38
VAQAHYQGKNHAKRL	ZMAT3	161	Q9HA38
LNDHQKIHTGVKLYK	ZNF12	396	P17014
HYKNPKLQHTVQAKS	PLEKHG1	386	Q9ULL1
KIVIQKYHTVNGHNC	HNRNPA1	161	P09651
GEQHVKGHQHNEKYK	ZNF318	1151	Q5VUA4
QQHYDGKKHKKNAAR	ZMAT4	161	Q9H898
SLKYNVVQHQKIHTG	ZNF17	256	P17021
KHSKNVYKAVGHYNV	TMEM39B	386	Q9GZU3
LTQHQKIHTGVKSYK	ZNF283	306	Q8N7M2
QLTQHQKIHTGKKPY	ZNF283	361	Q8N7M2
VGHYQQVSGLQKHSK	WNK3	621	Q9BYP7
DAKTIQTIKHHNKNY	LRRCC1	356	Q9C099
HHKGNAVLQSQVKYK	NEBL	326	O76041